thromboplastin and benzoylarginine-ethyl-ester

thromboplastin has been researched along with benzoylarginine-ethyl-ester* in 1 studies

Other Studies

1 other study(ies) available for thromboplastin and benzoylarginine-ethyl-ester

Article	Year
Activation of prothrombin as measured by the conversion of Nalpha-benzoylarginine ethyl ester. Biological chemistry Hoppe-Seyler, 1986, Volume: 367, Issue:5 The activation of prothrombin has been studied by using highly purified preparations of activated factor X1 and activated factor X2, factor V and prothrombin. The rate of prothrombin activation was followed using an esterase assay involving the conversion of N alpha-benzoylarginine ethyl ester (BAEE) by thrombin generated in the course of prothrombin activation. The rate of thrombin generation increased by about 26000-fold when factor V and phospholipid were added to prothrombin, factor Xa and calcium. A comparison of the rates of thrombin formation obtained with activated factor X1 and activated factor X2 showed that activated factor X1 had only 70% of the biological activity of activated factor X2. Attempts to explain the rate of prothrombin activation and the difference between the activity of activated factor X1 and activated factor X2 are discussed. Topics: Animals; Arginine; Calcium; Cattle; Enzyme Activation; Factor V; Factor X; In Vitro Techniques; Kinetics; Phospholipids; Prothrombin; Thromboplastin	1986

Article

Year

Activation of prothrombin as measured by the conversion of Nalpha-benzoylarginine ethyl ester.

Biological chemistry Hoppe-Seyler, 1986, Volume: 367, Issue:5

The activation of prothrombin has been studied by using highly purified preparations of activated factor X1 and activated factor X2, factor V and prothrombin. The rate of prothrombin activation was followed using an esterase assay involving the conversion of N alpha-benzoylarginine ethyl ester (BAEE) by thrombin generated in the course of prothrombin activation. The rate of thrombin generation increased by about 26000-fold when factor V and phospholipid were added to prothrombin, factor Xa and calcium. A comparison of the rates of thrombin formation obtained with activated factor X1 and activated factor X2 showed that activated factor X1 had only 70% of the biological activity of activated factor X2. Attempts to explain the rate of prothrombin activation and the difference between the activity of activated factor X1 and activated factor X2 are discussed.

Topics: Animals; Arginine; Calcium; Cattle; Enzyme Activation; Factor V; Factor X; In Vitro Techniques; Kinetics; Phospholipids; Prothrombin; Thromboplastin

1986