thrombin-aptamer and anthracene

thrombin-aptamer has been researched along with anthracene* in 1 studies

Other Studies

1 other study(ies) available for thrombin-aptamer and anthracene

Article	Year
Light-controlled thrombin catalysis and clot formation using a photoswitchable G-quadruplex DNA aptamer. Chemical communications (Cambridge, England), 2019, May-09, Volume: 55, Issue:39 The reversible photocontrol of an enzyme governing blood coagulation is demonstrated. The thrombin binding aptamer (TBA), was rendered photochromic by modification with two anthracene groups. Light-triggered anthracene photodimerisation distorts its structure, inhibiting binding of the enzyme thrombin, which in turn triggers catalysis and the resulting clotting process. Topics: Anthracenes; Aptamers, Nucleotide; Biocatalysis; Blood Coagulation; Circular Dichroism; Dimerization; G-Quadruplexes; Humans; Protein Binding; Temperature; Thrombin; Ultraviolet Rays	2019

Article

Year

Light-controlled thrombin catalysis and clot formation using a photoswitchable G-quadruplex DNA aptamer.

Chemical communications (Cambridge, England), 2019, May-09, Volume: 55, Issue:39

The reversible photocontrol of an enzyme governing blood coagulation is demonstrated. The thrombin binding aptamer (TBA), was rendered photochromic by modification with two anthracene groups. Light-triggered anthracene photodimerisation distorts its structure, inhibiting binding of the enzyme thrombin, which in turn triggers catalysis and the resulting clotting process.

Topics: Anthracenes; Aptamers, Nucleotide; Biocatalysis; Blood Coagulation; Circular Dichroism; Dimerization; G-Quadruplexes; Humans; Protein Binding; Temperature; Thrombin; Ultraviolet Rays

2019