threonine has been researched along with transforming growth factor beta in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (25.00) | 18.2507 |
| 2000's | 12 (42.86) | 29.6817 |
| 2010's | 6 (21.43) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Attisano, L; Cárcamo, J; Doody, J; Laiho, M; Massagué, J; Wang, XF; Wrana, JL; Zentella, A | 1 |
| Asplund, T; Heldin, P; Laurent, TC; Thelin, S; Ytterberg, D | 1 |
| Amagasa, T; Ichijo, H; Miyazono, K; Nishitoh, H; Saitoh, M; Takagi, M | 1 |
| Fujisawa, K; Funabiki, R; Ishizuka, S; Miura, Y; Yagasaki, K | 1 |
| Doré, JJ; Edens, M; Garamszegi, N; Leof, EB | 1 |
| Bennett, K; Dota, A; Kawasaki, S; Kinoshita, S; Nishida, K; Quantock, AJ | 1 |
| Dowdy, SF; Ezhevsky, SA; Kaldis, P; Nagahara, H; Solomon, MJ; Vocero-Akbani, AM | 1 |
| Cress, WD; Hu, X; Zhong, Q; Zuckerman, KS | 1 |
| Chang, NS | 1 |
| Ewton, DZ; Friedman, E; Jin, K; Kim, GY; Mercer, SE; Yan, Z | 1 |
| Burmester, JK; Polga, D; Salzman, SA; Zhang, KQ | 1 |
| McKeown-Longo, PJ; Zheng, M | 1 |
| Beniston, R; Catzavelos, C; Ciarallo, S; Connor, MK; Franssen, E; Han, K; Kotchetkov, R; Lee, JH; Liang, J; Petrocelli, T; Slingerland, JM; Zubovitz, J | 1 |
| Alessandrini, AA; Chadee, DN; Cohen, OS; Kyriakis, JM; Lin, HY; Raychowdhury, MK; Roelen, BA; Zhang, Y | 1 |
| Dubinett, SM; Huang, M; Keane, MP; Rozengurt, E; Sharma, S; Strieter, RM; Zhang, L; Zhu, LX | 1 |
| Chen, L; Ge, Z; Gu, Y; Guo, L; Qi, M; Si, J; Yan, X; Yang, Y; Yu, P | 1 |
| Ge, C; Haltiwanger, RS; Hou, X; Luo, Y; Shi, S; Stanley, P | 1 |
| Guo, X; Li, Z; Liu, X; Ramirez, A; Waddell, DS; Wang, XF | 1 |
| He, D; Liu, F; Matsuura, I; Wang, G | 1 |
| Chiang, KN; He, D; Lai, CY; Liu, F; Lu, K; Matsuura, I; Ramkumar, R; Ryo, A; Uchida, T; Wang, G | 1 |
| Heldin, CH; Morén, A; Moustakas, A; Raja, E | 1 |
| Chen, Q; Du, L; He, L; Hu, J; Liu, Y; Ni, B; Zhao, X; Zhu, D | 1 |
| Ji, YW; Kim, EK; Kim, TI; Lee, J; Park, SY; Seo, KY | 1 |
| Gao, S; Huang, J; Sixt, KM; Tripathi, V; Weigert, R; Xu, X; Zhang, YE; Zhou, M | 1 |
| Chiu, SY; Chung, HJ; Huang, CC; Huang, MS; Lin, Y; Liu, F; Matsuura, I; Yadav, P | 1 |
| Cho, JW; Ji, S; Kang, MJ; Kim, E; Kim, YJ; Kweon, TH; Park, YS; Yang, WH; Yi, EC | 1 |
| Jimenez, SA; Mendoza, FA | 1 |
| Birkou, M; Delegkou, GN; Episkopou, V; Fragkaki, N; Marousis, KD; Spyroulias, GA; Toro, T | 1 |
1 review(s) available for threonine and transforming growth factor beta
| Article | Year |
|---|---|
Serine/threonine kinase inhibition as antifibrotic therapy: transforming growth factor-β and Rho kinase inhibitors.
Topics: Fibrosis; Humans; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases; Serine; Threonine; Transforming Growth Factor beta; Transforming Growth Factors | 2022 |
27 other study(ies) available for threonine and transforming growth factor beta
| Article | Year |
|---|---|
TGF beta signals through a heteromeric protein kinase receptor complex.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cell Line; Mink; Models, Biological; Molecular Sequence Data; Multienzyme Complexes; Protein Kinases; Receptors, Cell Surface; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta | 1992 |
Characterization of the molecular mechanism involved in the activation of hyaluronan synthetase by platelet-derived growth factor in human mesothelial cells.
Topics: Cell Membrane; Cells, Cultured; Cycloheximide; Enzyme Activation; Epithelial Cells; Epithelium; Glucuronosyltransferase; Glycosyltransferases; Humans; Hyaluronan Synthases; Kinetics; Membrane Proteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Biosynthesis; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Threonine; Transferases; Transforming Growth Factor beta; Tyrosine; Vanadates; Xenopus Proteins | 1992 |
Identification of important regions in the cytoplasmic juxtamembrane domain of type I receptor that separate signaling pathways of transforming growth factor-beta.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Division; Cells, Cultured; Cytoplasm; DNA Primers; Epithelial Cells; Epithelium; Lung; Mink; Molecular Sequence Data; Mutagenesis; Phosphorylation; Receptors, Transforming Growth Factor beta; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta | 1996 |
Reduction of renal transforming growth factor-beta activity without aggravation of growth retardation in nephritic rats by a methionine-threonine-supplemented low-casein diet.
Topics: Animals; Caseins; Cell Line; Dietary Proteins; Eating; Food, Fortified; Growth Disorders; Humans; Kidney; Kidney Glomerulus; Male; Methionine; Mink; Nephritis; Rats; Rats, Wistar; Threonine; Transforming Growth Factor beta | 1997 |
Heteromeric and homomeric transforming growth factor-beta receptors show distinct signaling and endocytic responses in epithelial cells.
Topics: Activin Receptors, Type I; Amino Acid Substitution; Animals; Cell Division; Cell Line; Cell Membrane; Endocytosis; Epithelial Cells; Extracellular Matrix Proteins; Kinetics; Lung; Macromolecular Substances; Mink; Mutagenesis, Site-Directed; Point Mutation; Protein Multimerization; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Transfection; Transforming Growth Factor beta | 1998 |
Amyloid and Pro501 Thr-mutated (beta)ig-h3 gene product colocalize in lattice corneal dystrophy type IIIA.
Topics: Aged; Amyloid; Congo Red; Corneal Dystrophies, Hereditary; DNA; Exons; Extracellular Matrix Proteins; Humans; Immunoenzyme Techniques; Male; Neoplasm Proteins; Point Mutation; Polymerase Chain Reaction; Proline; Threonine; Transforming Growth Factor beta | 1999 |
Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity.
Topics: CDC2-CDC28 Kinases; Cyclin E; Cyclin H; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Cyclins; Down-Regulation; Enzyme Activation; G1 Phase; Humans; Models, Biological; Phosphorylation; Protein Serine-Threonine Kinases; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured | 1999 |
Transforming growth factor beta inhibits the phosphorylation of pRB at multiple serine/threonine sites and differentially regulates the formation of pRB family-E2F complexes in human myeloid leukemia cells.
Topics: Blotting, Western; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line; DNA; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; E2F3 Transcription Factor; E2F4 Transcription Factor; Gene Expression Regulation; Humans; Leukemia, Myeloid; Macromolecular Substances; Myeloid Cells; Nuclear Proteins; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Proteins; Retinoblastoma Protein; Retinoblastoma-Binding Protein 1; Retinoblastoma-Like Protein p107; Retinoblastoma-Like Protein p130; Serine; Threonine; Time Factors; Transcription Factor DP1; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured | 2000 |
The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression.
Topics: Animals; Ankyrins; Apoptosis; Cell Division; Cell Line; Cell Nucleus; COS Cells; Cytosol; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Dominant; Humans; Hyaluronoglucosaminidase; Hypoxia; I-kappa B Proteins; Liver; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Spleen; Staurosporine; Threonine; Time Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays | 2002 |
The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation.
Topics: Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Imidazoles; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Up-Regulation | 2002 |
Amino acids 67 and 68 of transforming growth factor-beta regulate binding to a glycosyl phosphatidyl inositol-linked membrane protein on vascular endothelial cells.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Cross-Linking Reagents; Cysteine; Endothelium, Vascular; Isoleucine; Ligands; Models, Molecular; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Swine; Threonine; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2 | 2002 |
Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cell Adhesion; Cell Division; Cell Line; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; Substrate Specificity; Thiazoles; Thiazolidines; Threonine; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine; Up-Regulation | 2002 |
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.
Topics: Active Transport, Cell Nucleus; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Line; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; Female; G1 Phase; Humans; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Survival Rate; Threonine; Transforming Growth Factor beta; Tumor Suppressor Proteins | 2002 |
Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Nucleus; Consensus Sequence; DNA-Binding Proteins; Genetic Linkage; LLC-PK1 Cells; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutation; Phosphoproteins; Phosphorylation; Protein Structure, Tertiary; Swine; Threonine; Trans-Activators; Transcription, Genetic; Transforming Growth Factor beta | 2003 |
Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis.
Topics: Blotting, Northern; Blotting, Western; Cell Line, Tumor; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Interleukin-7; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta; Up-Regulation | 2004 |
A clinical and molecular-genetic analysis of Chinese patients with lattice corneal dystrophy and novel Thr538Pro mutation in the TGFBI (BIGH3) gene.
Topics: China; Corneal Dystrophies, Hereditary; Female; Humans; Male; Mutation; Pedigree; Polymerase Chain Reaction; Proline; Threonine; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
The threonine that carries fucose, but not fucose, is required for Cripto to facilitate Nodal signaling.
Topics: Amino Acid Substitution; Animals; Cell Differentiation; Cell Line; Embryonic Stem Cells; Epidermal Growth Factor; Fucose; Fucosyltransferases; GPI-Linked Proteins; Humans; Intercellular Signaling Peptides and Proteins; Membrane Glycoproteins; Mice; Mutation, Missense; Myocytes, Cardiac; Neoplasm Proteins; Nodal Protein; Protein Modification, Translational; Receptor, Notch1; Signal Transduction; Threonine; Transforming Growth Factor beta | 2007 |
Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling.
Topics: Axin Protein; Cells, Cultured; Glycogen Synthase Kinase 3; Humans; Phosphorylation; Polyubiquitin; Proteasome Endopeptidase Complex; Repressor Proteins; Signal Transduction; Smad3 Protein; Threonine; Transforming Growth Factor beta; Ubiquitin-Protein Ligases; Wnt Proteins | 2008 |
Transforming growth factor-{beta}-inducible phosphorylation of Smad3.
Topics: Animals; Cell Line, Tumor; Fibroblasts; Flavonoids; Humans; Ligands; Mice; Mink; Models, Biological; Mutation; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Smad3 Protein; Threonine; Transforming Growth Factor beta | 2009 |
Pin1 promotes transforming growth factor-beta-induced migration and invasion.
Topics: Animals; Biocatalysis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Gene Knockdown Techniques; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Smad2 Protein; Smad3 Protein; Substrate Specificity; Threonine; Transforming Growth Factor beta | 2010 |
Negative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; AMP-Activated Protein Kinase Kinases; Animals; Cell Line, Tumor; DNA; Epithelial-Mesenchymal Transition; Humans; Mice; Molecular Sequence Data; Phosphorylation; Protein Multimerization; Protein Serine-Threonine Kinases; Protein Structure, Quaternary; Signal Transduction; Smad4 Protein; Threonine; Transcription, Genetic; Transforming Growth Factor beta | 2011 |
Threonine 32 (Thr32) of FoxO3 is critical for TGF-β-induced apoptosis via Bim in hepatocarcinoma cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Carcinoma, Hepatocellular; Cell Line, Tumor; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Membrane Proteins; Proto-Oncogene Proteins; Threonine; Transforming Growth Factor beta | 2015 |
Delayed Onset of Lattice Corneal Dystrophy Type IIIA Due to a Novel T621P Mutation in TGFBI.
Topics: Adult; Cornea; Corneal Dystrophies, Hereditary; DNA Mutational Analysis; Exons; Extracellular Matrix Proteins; Female; Humans; Male; Middle Aged; Pedigree; Point Mutation; Proline; Threonine; Tomography, Optical Coherence; Transforming Growth Factor beta; Visual Acuity | 2016 |
Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β.
Topics: Alternative Splicing; Animals; Cell Line, Tumor; DNA-Binding Proteins; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Exons; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Hyaluronan Receptors; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Neoplastic Stem Cells; Phosphorylation; Promoter Regions, Genetic; Protein Isoforms; RNA Precursors; RNA-Binding Proteins; Signal Transduction; Smad3 Protein; Threonine; Transforming Growth Factor beta | 2016 |
Impaired mammary tumor formation and metastasis by the point mutation of a Smad3 linker phosphorylation site.
Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Proliferation; Female; Gene Editing; Gene Knock-In Techniques; Humans; Lung Neoplasms; Mice; Mice, SCID; Phosphorylation; Point Mutation; Signal Transduction; Smad3 Protein; Threonine; Transforming Growth Factor beta; Triple Negative Breast Neoplasms; Valine; Xenograft Model Antitumor Assays | 2018 |
O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation.
Topics: Acetylglucosamine; Breast Neoplasms; Female; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Protein Processing, Post-Translational; Proteolysis; Serine; Signal Transduction; Smad4 Protein; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Ubiquitin | 2020 |
Unveiling the Essential Role of Arkadia's Non-RING Elements in the Ubiquitination Process.
Topics: Alanine; Arginine; Asparagine; Glutamine; Glycine; Isoleucine; Threonine; Transforming Growth Factor beta; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2022 |