threonine has been researched along with serine in 3078 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 874 (28.40) | 18.7374 |
| 1990's | 518 (16.83) | 18.2507 |
| 2000's | 950 (30.86) | 29.6817 |
| 2010's | 517 (16.80) | 24.3611 |
| 2020's | 219 (7.12) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Brittain, HG; Richardson, FS | 1 |
| Bhavanandan, VP; Davidson, EA; Umemoto, J | 1 |
| Coia, AA; Leader, DP | 1 |
| Drescher, DG; Lee, KS | 1 |
| Ishimoto, M; Kikuchi, S | 1 |
| Garnak, M; Reeves, HC | 1 |
| Chang, JY | 1 |
| Long, CW; Oskarsson, MK; Robey, WG; Scherer, MA; Vande Woude, GF | 1 |
| Kristiansen, K; Krüger, A | 1 |
| Cohen-Solal, L; Glimcher, MJ; Kossiva, D; Lian, JB | 2 |
| Glimcher, MJ; Kossiva, D; Roufosse, A | 1 |
| Brickley-Parsons, D; Glimcher, MJ; Kossiva, D | 1 |
| Glimcher, MJ; Kossiva, D; Lefteriou, B | 1 |
| Cozzone, A; Manaï, M | 1 |
| Radwan, P; Sacharuk, M; Sanecka-Obacz, M | 1 |
| Kieras, FJ | 1 |
| Baxter, E; Muir, H | 1 |
| Combe, E | 1 |
| Kawai, T; Takagi, K | 1 |
| Azhar, S; Menon, KM | 1 |
| Gardner, MB; McAllister, RM; Pal, BK; Roy-Burman, P | 1 |
| Krebs, EG; Stull, JT | 1 |
| Bachrach, HL; Matheka, HD | 1 |
| Honda, A; Kanke, Y; Mori, Y | 1 |
| Funakoshi, I; Nakada, H; Yamashina, I | 1 |
| Clari, G; Donella, A; Moret, V; Pinna, LA | 1 |
| Hayaishi, O; Shizuta, Y | 1 |
| Ponnamperuma, C; Sweeney, MA; Toste, AP | 1 |
| Agren, G; Ronquist, G | 4 |
| Benjamini, E; Graves, DJ; Kemp, BE; Krebs, EG | 1 |
| Tashiro, Y; Trevithick, JR | 1 |
| Kume, S; Nishida, T; Saito, M; Suda, M | 1 |
| Choppin, PW; Lamb, RA | 1 |
| Deana, AD; Meggio, F; Pinna, LA | 1 |
| Bailin, G | 1 |
| Cohen, P; Shenolikar, S | 1 |
| Hinoo, H; Kato, T; Shoji, J | 1 |
| Jeng, I | 1 |
| Jungmann, RA; Kranias, EG | 1 |
| Clari, G; Michielin, E; Moret, V | 1 |
| Bingham, EW; Traugh, JA; Tuazon, PT | 1 |
| Deana, D; Meggio, F; Pinna, LA | 1 |
| Castric, PA | 1 |
| Kleiman, JH; Moss, B | 1 |
| Roskoski, R; Witt, JJ | 1 |
| Cumming, G; Schrager, J | 1 |
| Dick, TE; Oxender, DL; Quay, SC | 1 |
| Ashman, PU; Newport, GR; Page, CR; Seed, JR; Stibbs, HH | 1 |
| Costrejean, JM; Truffa-Bachi, P | 1 |
| Ewald, R; Gualer, C | 1 |
| Montini, M; Ongaro, A; Simonutti, M | 1 |
| Hayaishi, O; Ito, S; Shizuta, Y; Watanabe, Y; Yui, Y | 1 |
| Doran, TI; Mattingly, SJ; Milligan, TW; Straus, DC | 1 |
| Cohen-Solal, L; Glimcher, M | 1 |
| Albani, M; Ishikura, H; Kersten, H; Murao, K | 1 |
| Bodanszky, M; Martinez, J; Tolle, JC | 1 |
| Marshall, RD | 2 |
| Hohmann, P | 1 |
| Bertolini, AM; Santagostino, A | 1 |
| Liao, TH; Wadano, A | 1 |
| Lessie, TG; Wong, HC | 1 |
| Biondi, A; Biondi, G; Gallone, U; Padula, P; Pignero, A; Quagliuolo, L | 1 |
| Cavadore, JC; Coletti-Previero, MA; Previero, A; Torreilles, J | 1 |
| Choughuley, AS; Kazi, ZA; Subbaraman, AS | 1 |
| Bantzer, P; Jäkel, A; Liappis, N | 1 |
| Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 2 |
| Downs, F; Murty, VL; Peterson, C; Pigman, W | 1 |
| Greenquist, AC; Shohet, SB; Wyatt, JL | 1 |
| Genest, M; Ptak, M | 1 |
| Blair, GE; Russell, WC | 1 |
| Axelrod, N | 1 |
| Kleinsmith, LJ; Pumo, DE | 1 |
| Peterson, NA; Raghupathy, E | 3 |
| Drujan, BD; van Gelder, NM | 1 |
| Hinoo, H; Shoji, J | 1 |
| Deutsch, HF; Fett, JW | 1 |
| Merinov, SP; Shirokov, VA | 1 |
| Bayley, HS; Chavez, ER | 1 |
| Yamashiro, D | 1 |
| Benkovic, SJ; Schirch, LV; Tatum, CM | 1 |
| Ehler, KW; Girard, E; Orgel, LE | 1 |
| Hill, HD; Hill, RL; Schwyzer, M; Steinman, HM | 1 |
| Kinnier, WJ; Wilson, JE | 1 |
| Chapman, DJ; Heaney-Kieras, J; Rodén, L | 1 |
| Horak, I; Schiffmann, D | 1 |
| Greenberg, R; Groves, ML; Peterson, RF | 1 |
| Kinzel, V; Kübler, D; Mastro, AM; Rozengurt, E | 1 |
| McCredie, KB; McGregor, RF; Wiseman, C | 1 |
| Linklater, J; van Heyningen, R | 1 |
| Bylund, DB; Huang, TS | 1 |
| Chavancy, G; Fournier, A; Garel, JP | 1 |
| Davis, L; Kapke, G | 1 |
| Chet, I; Henis, Y; Kritzman, G; Okon, Y | 1 |
| Clari, G | 1 |
| Lowe, NR; Robinson, C; Weatherell, JA | 1 |
| Hayes, ML; Hyatt, AT | 1 |
| Clark, CC; Kefalides, NA | 1 |
| Barker, JL; Nicoll, RA; Padjen, A | 1 |
| Dolowy, WC; Holcenberg, JS; Tang, E | 1 |
| Nass, G; Thomale, J | 1 |
| Bretthauer, RK; Wu, S | 1 |
| Guyer, RL; Lovins, RE; Schnute, WC; Todd, CW | 1 |
| Bayer, E; Hemmasi, B | 1 |
| Chellemi, F | 1 |
| Akhtar, M; El-Obeid, HA; Jordan, PM | 1 |
| Baker, DH; Katz, RS | 1 |
| Balikcioglu, S; Behnken, L; Besser, H; Förster, FJ; Grosshans, E; Neufahrt, A; Nowicki, L | 1 |
| Baetz, AL; Graham, CK; Hubbert, WT | 1 |
| Gundalakh, AI; Mel'k, MV; Shcheglova, SA; Volkova, ZA | 1 |
| Fein, JE; MacLeod, RA | 1 |
| Fendler, JH; Nagyvary, J; Nome, F | 1 |
| Chadha, MS; Choughuley, AS; Kazi, ZA; Subbaraman, AS | 1 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Bergner, H; Krieghoff, E | 1 |
| Humphrey, RM; Rupp, RG; Shaeffer, JR | 1 |
| Benassi, CA; Guggi, A; Rocchi, R; Salvadori, S; Tomatis, R | 1 |
| Côté, RH; Valet, JP | 1 |
| Heinrich, D; Kubli, F; Metz, J; Wesch, H | 1 |
| Goodfellow, JM; Morris, AS; Thanki, N | 1 |
| Derst, C; Henseling, J; Röhm, KH | 1 |
| Countaway, JL; Davis, RJ; Nairn, AC | 1 |
| Lin, HY; Lodish, HF; Ng-Eaton, E; Wang, XF; Weinberg, RA | 1 |
| Barrett, CB; Erikson, E; Maller, JL | 1 |
| Betz, H; Hoch, W; Langosch, D | 1 |
| Heidecker, G; Kölch, W; Morrison, DK; Rapp, UR | 1 |
| Lentz, SR; Sadler, JE; Tsiang, M | 1 |
| Akasaka, T; Ono, N; Sawai, T; Yamaguchi, A | 1 |
| Adler, V; Kraft, AS; Polotskaya, A; Wagner, F | 1 |
| Ishida, Y; Kawahara, Y; Koide, M; Tsuda, T; Yokoyama, M | 1 |
| Cohen, P; Lamond, AI; Mermoud, JE | 1 |
| Arnebrant, T; Glantz, PO; Rundegren, J; Vassilakos, N | 1 |
| Park, D; Rhee, SG | 1 |
| Attisano, L; Cárcamo, J; Doody, J; Laiho, M; Massagué, J; Wang, XF; Wrana, JL; Zentella, A | 1 |
| Faden, AI | 1 |
| Bowne, DB; Flores, E; Matthews, RJ; Thomas, ML | 1 |
| Forstner, G; Forstner, J; Huan, LJ; Xu, G | 1 |
| Sansom, MS | 1 |
| Brisson, JR; Helander, A; Kenne, L; Oscarson, S; Peters, T | 1 |
| Hotta, K; Ishii-Karakasa, I; Iwase, H | 1 |
| Charbonneau, H; Cool, DE; Fischer, EH; Tonks, NK | 1 |
| Haas, DW; Hagedorn, CH | 1 |
| Hunter, T; Lindberg, RA; Quinn, AM | 1 |
| Amess, B; Bianchi, R; Ceccarelli, P; Donato, R; Giambanco, I; Harris, AC; Howell, SA; Learmonth, MP; Patel, Y; Pula, G | 1 |
| Eldar, H; Livneh, E | 1 |
| Antonini, A; Bellezza, M; Cathala, B; Fellahi, JL; Richard, JP; Thouvenot, JP | 1 |
| Crimmins, DL; Davis, HW; McDonald, JM; Persechini, A; Sacks, DB | 1 |
| Botes, DP; Maeder, DL; Sunde, M | 1 |
| Hirayama, T; Oka, A | 1 |
| Maizels, RM; Page, AP | 1 |
| Taylor, SS; Toner-Webb, J; van Patten, SM; Walsh, DA | 1 |
| Cooper, JA; Posada, J | 1 |
| Alessandrini, A; Crews, CM; Erikson, RL | 1 |
| Crimmins, DL; Davis, HW; McDonald, JM; Sacks, DB | 1 |
| Nicholson, AW; Robertson, ES | 1 |
| Marin, O; Meggio, F; Perich, JW; Pinna, LA | 1 |
| Lee, GJ; McFadden, BA | 1 |
| Miles, EW; Yang, XJ | 1 |
| Broyles, SS; Chen, W; Lin, S | 1 |
| Asplund, T; Heldin, P; Laurent, TC; Thelin, S; Ytterberg, D | 1 |
| Chan, T; Lee, M; Sakmar, TP | 1 |
| Bergantino, E; Carignani, G; Frontali, L; Lanfranchi, G; Valle, G; Wilson, C | 1 |
| Faulkner, P; Whitford, M | 1 |
| Nelson, J; Qureshi, IA; Vasudevan, S | 1 |
| Rempel, RE; Traktman, P | 1 |
| Bornaes, C; Holmberg, S; Petersen, JG | 1 |
| Bordin, L; Clari, G; Moret, V | 1 |
| Cummings, RD; Do, SI | 1 |
| Biernat, J; Goedert, M; Gustke, N; Mandelkow, E; Mandelkow, EM; Meyer, HE; Steiner, B | 1 |
| Avruch, J; Brautigan, DL; Ingebritsen, TS; Kyriakis, JM | 1 |
| Bradley, TM; Lo, YH; Rhoads, DE | 1 |
| Lerea, KM | 1 |
| Lammers, R; Pillay, TS; Siddle, K; Ullrich, A; Whittaker, J | 1 |
| Clemetson, KJ; Kocher, M | 1 |
| Imahori, K; Ishiguro, K; Omori, A; Sato, K; Tomizawa, K; Uchida, T | 1 |
| Green, EG; Orme-Johnson, NR | 1 |
| Plasterk, RH; van Boom, JH; van der Marel, GA; Vink, C; Yeheskiely, E | 1 |
| Klee, CB; Stemmer, P | 1 |
| Imae, K; Kamachi, H; Naito, T; Ohbayashi, M; Okita, T; Okuyama, S; Sawada, Y; Tsuno, T; Yamasaki, T; Yamashita, H | 1 |
| Mendelsohn, J; Peacock, JS; Sunada, H; Yu, P | 1 |
| Anderson, SR; Malencik, DA; Zhao, ZZ | 1 |
| Iwashita, S; Mitsui, K | 1 |
| Kanner, SB; Parsons, JT; Reynolds, AB; Vines, RR; Wang, HC | 1 |
| Adams, EM; Atkinson, JP; Liszewski, MK; Miller, EA; Post, TW; Tedja, I | 1 |
| Altenhofen, W; Bönigk, W; Eismann, E; Kaupp, UB; Kraus, W; Ludwig, J | 1 |
| Baumann, M; Kauppinen-Mäkelin, R; Kontula, K; Koskinen, P; Lukka, M; Manninen, V; Mänttäri, M; Metso, J; Taskinen, MR; Tenkanen, H | 1 |
| Breckenridge, MB; Grants, IS; Liu, BQ; Newhouse, YG; Walters, JD; Whisler, RL | 1 |
| D'Souza, C; Elbein, AD; Sharma, CB | 1 |
| Blench, IP; Dell, A; Haltiwanger, RS; Hart, GW; Morris, HR; Panico, M; Reason, AJ | 1 |
| Chang, A; Slayman, CW | 1 |
| Dickens, M; Tavaré, JM | 1 |
| Dibrov, PA | 1 |
| Boynton, AL; Daily, SL; Dukelow, M; Honkanen, RE; Khatra, BS; Zwiller, J | 1 |
| Heyn, MP; Khorana, HG; Marti, T; Mogi, T; Otto, H; Rösselet, SJ | 1 |
| Alengrin, F; Ballotti, R; Dull, T; Lammers, R; Schlessinger, J; Tartare, S; Ullrich, A; Van Obberghen, E | 1 |
| Cummings, RD; Kuwano, M; Merkle, RK; Ono, M; Seguchi, T | 1 |
| Beidler, DR; Stern, DF; Zerillo, C; Zheng, P | 1 |
| Baird, A; Feige, JJ; Ling, N | 1 |
| Izumi, T; Kadowaki, T; Kasuga, M; Nagao, M; Takaku, F; Tamemoto, H | 1 |
| Kuwano, M; Ono, M; Seguchi, T | 1 |
| Arbus, GS; Goldberg, DM; Ish-Shalom, N; Macpherson, NA; Moscarello, MA | 1 |
| Carrell, RW; Daly, M; Harper, PL; Perry, DJ; Price, J; Tait, RC; Walker, ID | 1 |
| Hama, H; Kayahara, T; Tsuchiya, T; Tsuda, M | 1 |
| Classon, BJ; Gooley, AA; Marschalek, R; Williams, KL | 1 |
| Alexander, RS; Christianson, DW; Fierke, CA; Krebs, JF | 1 |
| Barbato, G; Bax, A; Ikura, M; Kay, LE; Krinks, M; Spera, S | 1 |
| Kanner, SB; Parsons, JT; Reynolds, AB; Vines, RR; Wu, H | 1 |
| Ellis, L; Roth, RA; Tavaré, JM; Zhang, B | 1 |
| Sotiroudis, TG; Xenakis, A | 1 |
| Kamiya, H; Muramoto, K | 1 |
| Imae, Y; Lee, L | 1 |
| Hirabayashi, Y; Iida, N; Ishizuka, I; Kanzaki, T; Matsubara, T; Matsumoto, M; Matsumoto, Y; Toida, T; Yokota, M | 1 |
| Countaway, JL; Davis, RJ; Gironès, N; McQuilkin, P | 1 |
| Levin, LR; Zoller, MJ | 1 |
| Horecker, BL; Panneerselvam, C; Wellner, D | 1 |
| Billadello, JJ; Fry, ET; Mack, DL; Monge, JC; Sobel, BE | 1 |
| Chiji, H; Harayama, K; Kiriyama, S | 1 |
| Anders, RF; Foley, M; Murray, LJ | 1 |
| Deuel, TF; Shawver, LK | 1 |
| LeMaster, DM; Markley, JL; Wang, JF | 1 |
| Mattice, WL; Tanpipat, N | 1 |
| Ikenaka, T; Mega, T; Nakamura, N | 1 |
| Clari, G; Marzaro, G; Moret, V | 1 |
| Avanov, AIa; Lipkind, GM | 1 |
| Goodfellow, JM; Thanki, N; Thornton, JM | 1 |
| Fiol, CJ; Gill, GN; Heisermann, GJ; Ingraham, HA; Walsh, BJ; Wiley, HS | 1 |
| Geschwill, K; Niemann, H; Simon, E; Tamura, T | 1 |
| Egawa, T; Imai, Y; Kitagawa, T; Ogura, T | 1 |
| Basdevant, A; Emi, M; Gambert, P; Hata, A; Iverius, PH; Lalouel, JM; Luc, G | 1 |
| Sakharova, IS; Torchinsky, YM; Zakomirdina, LN | 1 |
| Avruch, J; Gunsalus, JR; Price, DJ | 1 |
| Nagao, M; Tahira, T | 1 |
| Chinami, M; Goto, M; Ohtsu, Y; Shingu, M; Yuge, K | 1 |
| Miyasaka, J; Miyasaka, T; Saltiel, AR | 1 |
| Colbran, RJ; Soderling, TR | 1 |
| Brewis, ND; Cohen, PT; Hughes, V; Mann, DJ | 1 |
| Avruch, J; Kyriakis, JM | 1 |
| Aitken, A; Morrice, N | 1 |
| Etheredge, RW; Glimcher, MJ | 1 |
| Colca, JR; McCroskey, MC; Pearson, JD | 1 |
| Bagrodia, S; Choi, JK; Copeland, TD; Maller, JL; Shalloway, D; Shenoy, S | 1 |
| Boland, D; Goren, HJ; Neufeld, E | 1 |
| Gjika, HB; Levine, L; Van Vunakis, H | 1 |
| Imai, Y; Nakamura, M | 1 |
| Aning, KG; Thomlinson, JR | 1 |
| Goto, T; Hashimoto, M; Katayama, A; Nakada, H; Nishimura, M; Takase, S; Tanaka, H | 1 |
| Billadello, JJ; Fry, ET; Lucore, CL; Monge, JC; Sobel, BE | 1 |
| Adlakha, RC; Kuang, J; Rao, PN; Zhao, JY | 1 |
| Suzuki, M | 1 |
| Fujii, J; MacLennan, DH; Maruyama, K; Tada, M | 1 |
| Pessin, JE; Treadway, JL; Whittaker, J | 1 |
| Arendt, A; Caprioli, RM; Hargrave, PA; McDowell, JH; Moore, WT; Palczewski, K | 1 |
| Bdolah, A; Fleminger, G; Kochva, E; Wollberg, Z | 1 |
| Horiuchi, T; Imai, M; Ishimura, Y; Koga, H; Makino, R; Matsushima-Hibiya, Y; Shimada, H; Watanabe, Y | 1 |
| Leoncini, R; Marinello, E; Pagani, R | 1 |
| Ballotti, R; Scimeca, JC; Van Obberghen, E | 1 |
| Goldrick, SE; Loshon, CA; Setlow, P; Tovar-Rojo, F | 1 |
| Sanecka-Obacz, M | 1 |
| Sale, GJ; Smith, DM | 1 |
| Jones, LR; Lindemann, JP; Simmerman, HK; Wegener, AD | 1 |
| Cohen, P | 1 |
| Eisenman, RN; Firzlaff, JM; Galloway, DA; Lüscher, B | 1 |
| Daly, MP; Demediuk, P; Faden, AI | 1 |
| Christoph, G; Siman, R | 1 |
| Dobashi, K; Greene, MI; Weiner, DB | 1 |
| Hama, H; Shimamoto, T; Tsuchiya, T; Tsuda, M | 2 |
| de Graaf Mahoney, S; Foster, PA; Fulcher, CA; Houghten, RA; Zimmerman, TS | 1 |
| Bornaes, C; Holmberg, S; Kielland-Brandt, MC; Nilsson-Tillgren, T; Petersen, JG | 1 |
| Ray, LB; Sturgill, TW | 1 |
| Askanazi, J; Elwyn, DH; Gil, KM; Gump, FE; Kinney, JM; Starker, PM | 1 |
| Mora, F; Peinado, JM | 1 |
| Rechsteiner, M; Rogers, S; Wells, R | 1 |
| Rechsteiner, M | 1 |
| Cardini, CE; Moreno, S; Tandecarz, JS | 1 |
| Lu, PW; Tao, M | 1 |
| Li, XZ; Wang, KQ | 1 |
| Hartshorne, DJ; Ikebe, M; Koretz, J | 1 |
| Ballmer-Hofer, K; Benjamin, TL; Garcea, RL | 1 |
| Cooper, JA; Hunter, T | 1 |
| Corvera, S; Czech, MP; Davis, RJ; Lewis, RE; MacDonald, RG; Mottola, C; Necessary, PC; Yu, KT | 1 |
| Caron, MG; Cotecchia, S; DeBlasi, A; Leeb-Lundberg, LM; Lefkowitz, RJ | 1 |
| Montenarh, M; Müller, D | 1 |
| Herrera, R; Rosen, OM | 1 |
| Iwadare, S; Miyano, T; Sanada, M | 1 |
| de Boer, JE; Janssen, MA; Oostenbroek, RJ; Soeters, PB; van Dongen, JJ | 1 |
| el-Maghrabi, MR; Pilkis, SJ; Schworer, CM; Soderling, TR | 1 |
| Kuyl-Yeheskiely, E; Schaeffer, AH; Tromp, CM; van Boom, JH; van der Marel, GA | 1 |
| Abeijon, C; Hirschberg, CB | 1 |
| Christensen, HN; Flickinger, KS; Pisoni, RL; Thoene, JG | 1 |
| Ravnikar, PD; Somerville, RL | 1 |
| Feijen, A; Snoek, GT; van den Eijnden-van Raaij, AJ | 1 |
| Lorenzi, M; Marinello, E; Pagani, R; Rainis, R; Tabucchi, A | 1 |
| Black, S; Han, KH; Niu, CH; Yeh, HJ | 1 |
| Keleti, T; Leoncini, R; Marinello, E; Pagani, R | 1 |
| Abdel-Ghany, M; Katchalski-Katzir, E; Racker, E; Raden, D | 1 |
| Gerber, GE; Morton, RC | 1 |
| Garmendia, C; Hermoso, JM; Salas, M | 1 |
| Driessen, AJ; Konings, WN; Russell, JB; Strobel, HJ | 1 |
| Brenner, S | 1 |
| Gill, GN; Heisermann, GJ | 1 |
| Harper, AE; Tews, JK; Torres, N; Tovar, A | 1 |
| Griffiths, HS; Levine, BA; Patchell, VB; Perry, SV | 1 |
| Bárány, K; Bárány, M; Erdödi, F; Rokolya, A | 1 |
| Hashimoto, E; Kobayashi, T; Nakamura, S; Nishiyama, K; Sakai, K; Sakanoue, Y; Tanaka, Y; Yamamura, H | 1 |
| Creutz, CE; Summers, TA | 1 |
| Briskin, DP; Leonard, RT; Post, RL; Saccomani, G; Walderhaug, MO | 1 |
| Gasior, E; Grankowski, N; Kudlicki, W; Szyszka, R | 1 |
| Koerner, T; Olson, C; Rodén, L; Schwartz, NB | 1 |
| Gruber, C; Levine, S | 1 |
| Fujita, M; Makita, A; Oikawa, K; Ono, M; Taniguchi, N | 1 |
| DePaoli-Roach, AA; Lee, FT | 1 |
| Donella-Deana, A; Gasior, E; Grankowski, N; Kudlicki, W; Pinna, LA; Szyszka, R | 1 |
| Bause, E; Esche, H; Schughart, K | 1 |
| Casella, A; Leoncini, R; Marinello, E; Pagani, R | 1 |
| Chelladurai, M; Ganguly, CL; Ganguly, P | 1 |
| Lambrecht, B; Schmidt, MF | 1 |
| Inoue, S; Inoue, Y; Shimamura, M | 1 |
| Christensen, HN; Vadgama, JV | 1 |
| Garg, HG; Jeanloz, RW | 1 |
| Barker, HA; D'Ari, L | 1 |
| Ishijima, M; Ogawa, M; Takahara, A; Tazaki, S | 1 |
| Longbottom, JL; Pepys, J | 1 |
| Gerstenbrand, F; Gründig, E; Oberhummer, J; Schedl, R; Simanyi, M; Weiss, J | 1 |
| Bryce, GF | 1 |
| Asghar, SS; Harold, FM; Levin, E | 1 |
| Kakiuchi, S; Miyamoto, E | 1 |
| Abeles, RH; Krodel, E; Massey, V; Walsh, CT | 1 |
| Aprison, MH; Daly, E; McBride, WJ | 1 |
| Colley, L; Fox, FR; Huggins, AK | 1 |
| Kasarian, BA | 1 |
| Kennedy, AJ; Voaden, MJ | 1 |
| Cohen, GN; Truffa-Bachi, P; Veron, M | 1 |
| Bentley, CM; Dawes, EA | 1 |
| Jaton, JC | 1 |
| Clamp, JR; Dawson, G | 1 |
| De Lorenzo, F; Givol, D | 1 |
| Descamps, J; Monsigny, M; Montreuil, J | 1 |
| Givol, D; Rüde, E | 1 |
| Bundgaard, L; Winther, A | 1 |
| Kashima, N; Miyajima, R; Shiio, I | 1 |
| Murray, CL; Rabinowitz, JC; Samuel, CE | 1 |
| Antia, NJ; Kripps, RS | 1 |
| Cifonelli, JA; Mathews, MB | 1 |
| Schmid, DO; Uhlenbruck, G | 1 |
| Balduini, C; Castellani, AA; Laterza, L; Zonta, L | 1 |
| Brovelli, A; Castellani, AA; Laterza, L; Lenzi, L | 1 |
| Manley, G; Mullinger, RN | 1 |
| Eriksson, O; Hultberg, B; Ockerman, PA | 1 |
| Nemoto, T; Yosizawa, Z | 1 |
| Blat, C; Harel, L | 2 |
| Braun, W; Weiss, C; Zschaler, W | 1 |
| Seno, N; Toda, N | 1 |
| Kritcher, EM; Luchi, RJ; Thyrum, PT | 1 |
| Lloyd, KO | 1 |
| Mårdh, S; Zetterqvist, O | 1 |
| Sinoara, H | 1 |
| Davidson, EA; Hranisavljevic, J; Simpson, DL | 1 |
| Dziewiatkowski, DD; Hascall, VC; Riolo, RL | 1 |
| Atherton, DM; Margolis, RK; Margolis, RU | 1 |
| Rosenberg, L | 1 |
| Andersen, AE; Guroff, G; Rowe, VD; Sidbury, JB; Zigler, S | 1 |
| Adye, JC; Murthy, JR; Springer, GF | 1 |
| Herbert, E; Smith, CJ | 1 |
| Borghetti, AF; Guidotti, GG; Lüneburg, B | 1 |
| Allen, RE; Raines, PL; Regen, DM | 1 |
| Bensusan, HB | 1 |
| Knull, HR; Pazur, JH; Simpson, DL | 1 |
| Erikson, E; Erikson, RL | 1 |
| Berry, SA; Campbell, JN; Johnson, KG | 1 |
| Nishizuka, Y; Takeda, M; Yamamura, H | 1 |
| Schlitz, E; Sekeris, CE | 1 |
| Majumder, GC; Turkington, RW | 1 |
| Clari, G; Moret, V; Pinna, LA | 1 |
| DeBernardo, SL; Jamieson, GA; Jett, M | 1 |
| Asano, Y; Fukui, A; Sinoara, H | 1 |
| Brandt, KD; Muir, H | 1 |
| Gregory, EM; Harrison, JH; Rohrbach, MS | 1 |
| Karadźić, V; Micić, D; Rakić, L | 1 |
| Greengard, P; Maeno, H | 1 |
| Cagen, LM; Friedmann, HC | 1 |
| Traugh, JA; Traut, RR | 1 |
| Mitchell, JF; Roberts, PJ | 1 |
| Mumby, M; Trauch, JA; Traut, RR | 1 |
| Appel, SH; Roses, AD | 1 |
| Mauron, J; Mottu, F; Spohr, G | 1 |
| Cawley, TN; Harrington, MG; Letters, R | 1 |
| Almon, RR; Andrew, CG; Appel, SH; Roses, AD | 1 |
| Deschenes, M; Labrie, F; Lemaire, S; Lemay, A; Poirier, G; Poulin, L | 1 |
| Kish, VM; Kleinsmith, LJ | 1 |
| Busch, H; Jones, C; Olson, MO; Orrick, LR | 1 |
| Ballou, CE; Yen, PH | 2 |
| Kakimoto, Y; Kakiuchi, S; Miyamoto, E | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Rustioni, A; Sanyal, S | 1 |
| Margoliash, E; Putterman, GJ; Sherman, F | 1 |
| Burns, RO; Decedue, CJ; Hofler, JG; Luginbuhl, GH | 1 |
| Kaback, HR; Short, SA | 1 |
| Oates, MD; Schrager, J | 3 |
| Emmens, M; Konings, WN; Kuenen, JG; Matin, A | 1 |
| Garner, HR; Jenkins, MB | 1 |
| Kari, A; Kulonen, E; Lapiaho, K; Pikkarainen, J; Rantanen, J; Vastamäki, M | 1 |
| Miyajima, R; Otsuka, S; Shiio, I | 1 |
| Sanchez, A; Swendseid, ME | 1 |
| Allfrey, VG; Teng, CS; Teng, CT | 1 |
| Kuhn, J; Somerville, RL | 1 |
| Forestier, M; Girard-Globa, A; Robin, P | 1 |
| Turner, JM; Willetts, AJ | 1 |
| Read, CP; Southworth, GC | 1 |
| Yamamoto, M; Young, JL | 1 |
| Sharon, N; Zehavi, U | 1 |
| Aktin, E; Bergisadi, N; Güven, KC; Koyuncuoglu, H | 1 |
| Cierniewski, C; Krajewski, T | 1 |
| Allen, WS; Varma, R; Varma, RS; Wardi, AH | 2 |
| Gressner, AM; Wool, IG | 1 |
| Allsopp, MN; Hullin, RP; Rees, JR | 1 |
| Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
| Maier, R; Riniker, B; Rittel, W | 1 |
| Hass, LF; Jarboe, CJ; Noll, BW | 2 |
| Jäkel, A; Liappis, N | 1 |
| Ambani, LM; Liu, YP; Van Woert, MH | 1 |
| Crossley, AC; Evans, PD | 1 |
| Goodwin, SD; Watkins, WM | 1 |
| Gold, DV; Miller, F | 1 |
| Friedmann, N; Miller, SL; Ring, D; Wolman, Y | 1 |
| Attardi, G; Costantino, P | 1 |
| Ventimiglia, FA; Wool, IG | 1 |
| Elsässer, S; Holzer, H; Katsunuma, T; Schött, E | 1 |
| Stuttard, C | 1 |
| Apell, G; Carr, WR; Huisman, TH; Schroeder, WA; Shelton, JB; Shelton, JR; Smith, LL | 1 |
| Peterkofsky, A; Powers, DM | 1 |
| Allen, A; Snary, D | 2 |
| Adler, J; Mesibov, R | 1 |
| Nakazawa, A; Tokushige, M | 1 |
| Bridges, KR; Jones, GH | 1 |
| Miller, EJ | 1 |
| Sunde, ML | 1 |
| Oxender, DL; Robbins, JC | 1 |
| Claus, DR; Oxender, DL; Rahmanian, M | 1 |
| Fuchs, S; Inouye, H; Littauer, UZ; Sela, M | 1 |
| Chibata, I; Kisumi, M; Komatsubara, S | 1 |
| Hayaishi, O; Inoue, K; Kurosawa, A; Shizuta, Y; Tanabe, T | 1 |
| Falmagne, P; Wiame, JM | 1 |
| Savageau, MA; Templeton, BA | 1 |
| Isenberg, S; Newman, EB | 1 |
| Colonna, WJ; Lampen, JO | 1 |
| Babczinski, P; Lehle, L; Sharma, CB; Tanner, W | 1 |
| Kamihara, T; Tokushige, M | 1 |
| Halpern, YS | 1 |
| Pittsyn, OB | 1 |
| Edmunds, LN; Sulzman, FM | 1 |
| Hegazi, SM; Morcos, SR; Salem, SI | 1 |
| Lajtha, A; Sershen, H; Seta, K | 1 |
| Coulson, RA; Herbert, JD | 1 |
| Baker, DH; Boomgaardt, J | 1 |
| Desmarais, M; Pare, JP | 1 |
| Araya, A; Goodman, M; Maita, T; Matsuda, G; Ota, H; Prychodko, W; Watanabe, B | 1 |
| Durbin, RD; Schnoes, HK; Taylor, PA | 1 |
| Bange, C | 1 |
| Ando, T; Suzuki, K | 2 |
| Büchner, M; Hofmann, F; Scheid, P | 1 |
| Okano, T; Sato, Y | 1 |
| Fiedler, F; Kandler, O; Schleifer, K | 1 |
| Meister, A; Palekar, AG; Tate, SS | 1 |
| Hsueh, HW; Moskowitz, M | 1 |
| Behr, FE; Campbell, RD | 1 |
| Chen, MS; Schirch, LV | 1 |
| Gutman, AB; Yu, TF | 2 |
| Gruber, L; Harris, JE | 1 |
| Moss, B; Rosemond, H | 1 |
| Owen, CA; Tyce, GM | 1 |
| Adibi, SA; Amin, PM; Modesto, TA; Morse, EL | 1 |
| Capaldi, RA | 1 |
| Wålinder, O | 2 |
| Lowenstein, LM; Mayers, AM; Toback, FG | 1 |
| Gurd, FR; Keim, P; Marshall, RC; Morrow, JS; Vigna, RA | 1 |
| Grenouillet, P; Martin, RP; Ptak, M; Rossi, A | 1 |
| Banas, Z; Cierniewski, C; Krajewski, T | 1 |
| Maruyama, T; Sinohara, H | 1 |
| Cohn, MS; Phillips, AT | 1 |
| Glassman, E; Machlus, BJ; Wilson, JE | 1 |
| Fridkin, M; Goren, HJ | 1 |
| Drewes, LR; Gander, JE; Rick, PD | 1 |
| Bernstein, IA; Gray, RH; Sibrack, LA | 1 |
| Jörnvall, H; Ohlsson, H; Philipson, L | 1 |
| Giorgio, AJ; Linarelli, LG; Macdonald, RR; Rubin, HM | 1 |
| Jones, NS; Lamkin, WM; Pan, T; Ward, DN; Weatherford, JW | 1 |
| Carnegie, PR; Dunkley, PR; Kemp, BE; Murray, AW | 1 |
| Eil, C; Wool, IG | 1 |
| Pigman, W; Wakabayashi, K | 1 |
| Doores, L; Schulman, JD; Silagi, S; Wrathall, JR | 1 |
| Boling, JA; Bradley, NW; Cross, DL; Ludwick, RL | 1 |
| Anandaraj, MP; Cherayil, JD | 1 |
| Huang, HT | 1 |
| Datta, P | 2 |
| Hütter, R; Poralla, K; Zachau, HG; Zähner, H | 1 |
| Kaback, HR; Stadtman, ER | 1 |
| Short, WA; Tomisek, AJ | 1 |
| Cohen, GN; Gros, C; Janin, J; Truffa-Bachi, P; Van Rapenbusch, R | 1 |
| Sakiyama, F | 1 |
| Goldberg, ME; Stryer, L; York, S | 1 |
| Iwashima, A; Kawasaki, T; Nakamura, M; Nose, Y | 1 |
| Cafferata, RL; Freundlich, M | 1 |
| Berger, H; Yanofsky, C | 1 |
| Harada, T; Murooka, Y; Seto, K | 1 |
| Sekiya, T; Ukita, T | 1 |
| Arnold, RL; Kakade, ML; Liener, IE; Waibel, PE | 1 |
| Abramovitz, AS; Nixon, JE; Phillips, GT; Porter, JW | 1 |
| Degani, Y; Patchornik, A; Spande, TF; Witkop, B | 1 |
| Kagan, ZS; Tomova, VS | 1 |
| Engström, L; Rask, L; Wålinder, O; Zetterqvist, O | 1 |
| Spiro, RG | 1 |
| Ishikura, H; Nishimura, S; Yamada, Y | 1 |
| Elfving, R; Raunio, R | 1 |
| Kishida, Y; Sakakibara, S | 1 |
| Milne, MD | 1 |
| Pizer, LI; Tosa, T | 1 |
| Alföldi, L; Raskó, I | 1 |
| Beaudet, A; Caskey, CT; Nirenberg, M | 1 |
| Hampton, JR | 1 |
| Balhorn, R; Chalkley, R; Rieke, WO | 1 |
| Dunathan, HC | 1 |
| Hunt, DE | 2 |
| Castellani, AA | 1 |
| Feder, J | 1 |
| Buchet, MT; Monsigny, M; Montreuil, J | 1 |
| Doi, RH; Horikoshi, K | 1 |
| Kojima, H; Sugae, K | 1 |
| Mikes, O; Sorm, F; Toan, NB; Turková, J | 1 |
| Beuvery, EC; Dijk, J; Gruber, M; Konings, WN; Wichertjes, T | 1 |
| Doi, RH; Migita, LK | 1 |
| Goldman, M; Griffin, AC | 1 |
| Kabat, D | 1 |
| Cahill, CF; Felig, P; Marliss, E; Ohman, JL | 1 |
| Bourrillon, R; Jouanneau, J; Razafimahaleo, E | 1 |
| Jamieson, GA; Pepper, DS | 1 |
| Greer, S; Vapnek, D | 2 |
| Horowitz, MI; Kim, YS | 1 |
| Gupta, YP | 1 |
| Cicmanec, J; Koll, M; Seaman, GR | 1 |
| Cohen HP LIN, S | 1 |
| Ayala, GF; Cohen, HP; Vasconetto, C | 1 |
| Arima, T; Spiro, MJ; Spiro, RG | 1 |
| Akhtar, M; el-Obeid, HA | 1 |
| Felig, P; Hendler, R; Kim, YJ; Lynch, V | 1 |
| Korth, H | 2 |
| Cheyne, GA; Hytten, FE | 1 |
| Stübchen-Kirchner, H | 1 |
| Burt, D; Emery, AE | 1 |
| Hoshino, J; Kröger, H; Simon, D | 2 |
| Boling, JA; Bradley, NW; Willard, JC | 1 |
| Bitte, L; Kabat, D | 1 |
| Nagchaudhuri, J; Ozalp, I; Scrimshaw, NS; Tontisirin, K; Young, VR | 1 |
| MacLeod, MB; Pitts, RF | 1 |
| Maret, R | 1 |
| Degand, P; Havez, R; Lamblin, G; Roussel, P | 1 |
| Barry, LG; Coletti-Previero, MA; Previero, A | 1 |
| Codington, JF; Jeanloz, RW; Sanford, BH | 1 |
| Nath, M; Sanwal, GG | 1 |
| Hafez, ES; Jaszczak, S | 1 |
| Boyd, H; Leach, SJ; Milligan, B | 1 |
| Roberts, E; Tunnicliff, G; Wein, J | 1 |
| Moss, B; Paoletti, E | 1 |
| Hladny, J; Kandler, O; Schleifer, KH | 1 |
| Matsumura, S; Takeda, M | 1 |
| Morishita, S; Muramatsu, K; Odagiri, H; Takeuchi, H | 1 |
| Ono, T; Tasaki, I | 1 |
| Franzblau, C; Hollander, W; Kramsch, DM | 1 |
| Campbell, DJ; Reid, DW; Yakymyshyn, LY | 1 |
| Clark, WT; Cuddeford, D | 1 |
| Fairwell, T; Lovins, RE | 1 |
| Fernstrom, JD; Larin, F; Wurtman, RJ | 1 |
| Barkin, E; Levy, HL | 1 |
| Ponnuswamy, PK; Sasisekharan, V | 2 |
| Shearer, TR; Suttie, JW | 1 |
| Carlson, DM; Neiderhiser, DH; Plantner, JJ | 1 |
| Mead, GC | 1 |
| Christensen, HN; Koser, BH | 1 |
| Hornig, D; Weber, F; Wiss, O | 1 |
| Freinkel, N; Hare, JW; Metzger, BE | 1 |
| Egami, F; Fukuda, M | 1 |
| Thomas, DB; Winzler, RJ | 1 |
| Markelova, SI; Zharikova, GG | 3 |
| Wolff, H | 1 |
| Ermol'eva, ZV; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA | 1 |
| Anderson, DM; Hendrie, A | 1 |
| Chizhov, OS; Derevitskaya, VA; Kochetkov, NK; Likhosherstov, LM; Novikova, OS; Zolotarev, BM | 1 |
| Dickson, IR; Perkins, DJ | 1 |
| Okazaki, M; Sasaki, T; Tanemura, K | 1 |
| Buck, CA; Granger, GA; Holland, JJ; Taylor, MW | 1 |
| Hirsh, DI; Konigsberg, WK; Rifkin, DB; Rifkin, MR | 1 |
| Gibbons, RJ; Loesche, WJ | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Kolosova, NN; Zozuliakova, SV | 1 |
| Hellman, A; Hellman, KB; Martin, DH; Novelli, GD; Yang, WK | 1 |
| Gallo, RC; Pestka, S | 1 |
| Geisler, C; Höcker, P; Stacher, A; Wiser, M | 1 |
| Geary, CP; Smillie, AC; Wesson, CM | 1 |
| Banerjee, M; Banerjee, SN; Horsley, RJ | 1 |
| Grunberg-Manago, M; McLaughlin, CS | 1 |
| Labow, R; Robinson, WG | 1 |
| Dunnill, PM; Fowden, L | 1 |
| Adler, J; Armstrong, JB; Dahl, MM | 1 |
| Jones, OW; Nirenberg, MW | 1 |
| Appella, E; Martin, RG; Voll, MJ | 1 |
| Cennamo, C | 1 |
| Popp, RA | 1 |
| Barois, A; Caldera, R; Escourolle, R; Goulon, M; Grosbuis, S; Nouailhat, F | 1 |
| Anderson, HL; Benevenga, NJ; Harper, AE | 3 |
| Riddle, M; Turkington, RW | 1 |
| Gebert, U; von Kerékjártó, B | 1 |
| Cawley, TN; Letters, R | 1 |
| Hulcher, FH; Newkirk, JD | 1 |
| Kathan, RH; Weeks, DI | 1 |
| Cepurneek, CP; Davis, PS; Multani, JS; Saltman, P | 1 |
| Kapoor, IJ; Tandon, RN | 1 |
| Nunn, PB; Vega, A | 1 |
| Bowman, F; Harrill, I; Lakhanpal, RK | 1 |
| Hoshino, S; Tsubota, H | 1 |
| Ermol'eva, ZV; Pokidova, NV; Zhuravleva, TP | 1 |
| Hatano, M; Obara, Y; Ono, S | 1 |
| Downs, F; Pigman, W | 1 |
| Griffin, GE; Kesner, L; Muntwyler, E; Sanslone, WR | 1 |
| Lee, YC; Muir, L | 1 |
| Abbott, EH; Martell, AE | 1 |
| Dainty, RH; Peel, JL | 1 |
| Berl, S; Santini, M | 1 |
| Schrager, J | 1 |
| Oettmeier, W | 1 |
| Lanks, KW | 1 |
| Blackburn, MN; Chatterjee, GC; Noltmann, EA; Pon, NG; Schnackerz, KD | 1 |
| Kumagai, H; Nagate, T; Yamada, H; Yoshida, H | 1 |
| Cohen, GN; Poiret, M; Robert-Gero, M | 1 |
| Ermol'eva, ZV; Evseenko, LK; Iulikova, EP; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA; Silaev, AB | 1 |
| Lohrenz, FN; Tewksbury, DA | 1 |
| Kornfeld, R; Kornfeld, S | 1 |
| Bowman, RL; Ito, Y; Pisano, JJ; Tanimura, T | 1 |
| Lacy, WW | 1 |
| Grimble, RF; Whitehead, RG | 1 |
| Haber, E; Waterfield, M | 1 |
| Carton, D; De Schrijver, F; Delbeke, MJ; Dhondt, F; Hooft, C; Kint, J; Samyn, W | 1 |
| Giormani, V; Marzotto, A | 1 |
| Neuhoff, V; Weise, M | 1 |
| Baker, BE; Tran, VD | 1 |
| Nobel, PS; Wang, CT | 1 |
| Christensen, HN; Thomas, EL | 1 |
| Jungermann, KA; Kirchniawy, FH; Rupprecht, EH; Schmidt, W; Thauer, RK | 1 |
| Gerstenbrand, F; Gründig, E | 1 |
| Alaupovic, P; Furman, RH; McConathy, WJ; Seidel, D | 1 |
| McKean, CM; Peterson, NA | 1 |
| Dayhoff, MO; Hunt, LT | 1 |
| Melcher, G | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Boublík, M; Bradbury, EM; Crane-Robinson, C | 1 |
| Kearney, EB; Kenney, WC; Singer, TP; Walker, WH; Zeszotek, E | 1 |
| Linkswiler, H; Park, YK | 1 |
| Oga, Y; Takeda, M; Yamamura, H | 1 |
| King, L; Perham, RN | 1 |
| DeMoss, RD; Hoch, JA; Roth, CW | 1 |
| Tauschel, HD | 1 |
| Balasubramanian, M; Myers, RF | 1 |
| Kerly, M; Spruyt, JE | 1 |
| Pickrell, JA; Shafer, J | 1 |
| Diller, A; Schirch, LV | 1 |
| Battistin, L; Grynbaum, A; Lajtha, A | 1 |
| Flory, B; Krassner, SM | 1 |
| Forest, JC; Wightman, F | 1 |
| Debusk, AG; Wolfinbarger, L | 1 |
| Spence, KD | 1 |
| Dryden, LP; Hartman, AM | 1 |
| Hopkins, L; McFadyen, IR; Young, M | 1 |
| Milstein, C; Murray, K | 1 |
| Kloss, G; Schwarz, E | 1 |
| Bubenshchikova, SN; Katrukha, GS; Kharchenko, LI; Silaev, AB; Trufonova, ZhP | 1 |
| Schmitt, A; Siebert, G | 1 |
| Gusev, EI | 1 |
| Ansorge, S; Bohley, P | 1 |
| Bhargava, AS; Gottschalk, A | 1 |
| Daniel, JC; Krishnan, RS | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| McLemore, WO; Metzler, DE | 1 |
| Lang, D; Lee, YC | 1 |
| Bartelt, DC; DiCarlo, JJ; Greene, LJ; Sussman, AJ | 1 |
| Björnesjö, KB | 1 |
| Pikkarainen, J | 1 |
| Dénes, G; Vincze, I | 1 |
| Bojanowska, K; Williamson, DH | 1 |
| Blumenfeld, OO; Gallop, PM; Henson, E; Schneider, AL | 1 |
| Kristiansen, T; Porath, J | 1 |
| Clauser, S; Harbon, S; Herman, G | 1 |
| Björenesjö, KB | 1 |
| Balint, JA; Kyriakides, EC | 1 |
| Brown, HH | 1 |
| Manahan, J; Mandl, I | 1 |
| Fraunberger, F; Pietta, P; Schmid, J; Steglich, W; Weygand, F | 1 |
| Northcote, DH; Sentandreu, R | 1 |
| Meun, DH; Smith, KC | 1 |
| Holman, G; Lowe, JS; Morley, JS; Smithers, MJ | 1 |
| Bonner, J; DeLange, RJ; Fambrough, DM; Smith, EL | 1 |
| Gross, T; Schirch, L | 1 |
| Bairos, MA; Bairos, VA | 1 |
| Dodgson, KS; Thomas, JH; Tudball, N | 1 |
| Eaton, SW; Vernon, RG; Walker, DG | 1 |
| Barabás, G; Szabó, G | 1 |
| Allen, AK; Rosenberg, H | 1 |
| Holcomb, GN; James, SA; Lamkin, WM; Wade, J; Ward, DN | 1 |
| Deer, A; Kocy, O; Ondetti, MA; Pluscec, J; Sheehan, JT | 1 |
| Murray, K | 1 |
| Padberg, G | 1 |
| Ota, S | 1 |
| Hertel, W; Rohrlich, M | 1 |
| Killilea, SD; O'Carra, P | 1 |
| Samofalova, MS | 1 |
| Gulian, EA; Kazarian, BA | 1 |
| Farid, SA; Kozloff, LM | 1 |
| Hanson, H; Kettmann, U; Kretschmer, K | 1 |
| Payza, N; Pigman, W; Rizvi, S | 1 |
| Allfrey, VG; Kleinsmith, LJ | 1 |
| Beyer, H; Schenk, U | 1 |
| Hass, LF; Sine, HE | 1 |
| Landau, RL; Lugibihl, K | 1 |
| Schroeder, WA; Shelton, JB; Shelton, JR | 1 |
| Darbre, A; Del Favero, A; Waterfield, M | 1 |
| Adler, M; Bobrow, E; Gutman, AB; Yü, TF | 1 |
| Beisel, WR; Dangerfield, HG; Feigin, RD | 1 |
| Pine, MJ; Sarimo, SS | 1 |
| Bonney, R; Grace, JT; Hall, RH; Mittelman, A | 1 |
| Berge, T; Borgfors, N; Brun, A; von Studnitz, W | 1 |
| Hoshino, J; Kröger, H | 1 |
| Bieber, G; Cesario, S | 1 |
| Ingram, LC | 1 |
| Gross, S; Maskaleris, ML; Milhorat, AT | 1 |
| Kulonen, E; Pikkarainen, J | 1 |
| Biserte, G; Degand, P; Delmas-Marsalet, Y; Havez, R; Roussel, P | 1 |
| Hohenegger, M; Kaiser, E; Raab, W | 1 |
| Gordon, WG; Greenberg, R; Pepper, L; Thompson, MP | 1 |
| Menden, E; Vangala, RR | 1 |
| McCormick, DB; Sigel, H; Wright, LD | 1 |
| Messineo, L | 1 |
| Gineitis, AA; Vinogradova, IA; Vorobyev, VI | 1 |
| Koshiyama, I | 1 |
| Lampen, JO; Neumann, NP | 1 |
| Mankovitz, R; Segal, HL | 1 |
| Anderson, HL; Linkswiler, H | 1 |
| Greiling, H; Kisters, R; Ohlenbusch, HD; Vögele, P | 1 |
| Noda, Y | 1 |
| Naftalin, L; Stephens, A | 1 |
| Best, JS; Bhavanandan, VP; Gottschalk, A | 1 |
| Bassett, EW; Kabat, EA; Kaplan, ME; Layug, EJ; Lloyd, KO; Pryzwansky, K | 1 |
| Ikehara, M; Ohtsuka, E | 1 |
| Schneider, F | 2 |
| Bhavanandan, VP; Buddecke, E; Carubelli, R; Gottschalk, A | 1 |
| Bertolini, M; Pigman, W; Tanaka, K | 1 |
| Boll, M; Holzer, H | 1 |
| Porcellati, G; Simoncini, I | 1 |
| Ciammarughi, A; Floridi, A; Montanini, I; Porcellati, G | 1 |
| Montanini, I; Porcellati, G; Simoncini, I | 1 |
| McEvoy-Bowe, E; Sarojini Thevi, S | 1 |
| Dennis, ES; Goodchild, CG | 1 |
| Money, WL; Sonenberg, M | 1 |
| Pengra, RM; Yoch, DC | 1 |
| Tahara, M; Whiteley, HR | 1 |
| Fölsch, G | 1 |
| Herbert, E; Smith, CJ; Smith, PM | 1 |
| Balakir, RA; Moffitt, TE; Riley, V; Schaffer, NK | 1 |
| Huang, JM; Wang, IS; Wang, KT | 1 |
| Christian, JH; Waltho, JA | 1 |
| Mepham, TB; Smith, MW | 1 |
| Havsteen, BH | 1 |
| Mehran, AR; Pageau, R | 1 |
| Fujita, T; Hoshino, O; Ikekawa, N; Orimo, H; Watanuki, R; Yoshikawa, M | 1 |
| Gurley, LR; Kischer, CW; Shepherd, GR | 1 |
| Ebata, M; Otsuka, H; Takahashi, Y | 1 |
| Aurich, H | 1 |
| Christophe, J; Wodon, C | 1 |
| Gutermann, H; Waldschmidt-Leitz, E | 1 |
| Marutian, SA | 1 |
| Andreeva, LA | 1 |
| Carver, MJ; Ryan, WL | 1 |
| Watt, WB | 1 |
| Pitts, RF; Stone, WJ | 1 |
| Bourke, JB; Massey, LM; Stillings, BR | 1 |
| Adamson, LF; Ingbar, SH | 1 |
| Kathan, RH; Reichert, LE; Ryan, RJ | 1 |
| Francis, FJ; Fuleki, T | 1 |
| Mohri, T | 1 |
| Rigby, BJ | 1 |
| Horler, DF; McConnell, WB; Westlake, DW | 1 |
| Estes, FL; Wetzel, RL | 1 |
| Giovanelli, J; Mudd, SH | 1 |
| Kuttner, RE; Lorincz, AB; Portoghese, A | 1 |
| Harper, E; Scharrer, B; Seifter, S | 1 |
| Efron, ML; Mechanic, GL; Shih, VE | 1 |
| Lopes-Vieira, O; Walker, B; Williamson, DH | 1 |
| Masukawa, H; Tanaka, N; Umezawa, H | 1 |
| Oliver, IT; Yeung, D | 1 |
| Harris, ED; Johnson, CA; Pekas, DJ; Weber, P; Winzler, RJ | 1 |
| D'Angeli, F; Di Bello, C; Filira, F; Giormani, V | 1 |
| Agnihotri, VP; Vaartaja, O | 1 |
| Arcà, M; Frontali, L; Sapora, O; Tecce, G | 1 |
| Davis, L; Dixon, E | 1 |
| Sharma, VS | 1 |
| Kuroda, Y | 1 |
| Chan, WW; Li, HC | 1 |
| Brockhausen, I; Gleeson, P; Narasimhan, S; Schachter, H; Vella, GJ | 1 |
| Haselbeck, A; Lehle, L; Schwaiger, H; Tanner, W | 1 |
| Miller, RD; Morse, SA; Tesh, MJ | 1 |
| Bhatnagar, R; Chauhan, BS; Desai, NC; Garg, SP | 1 |
| Mora, F; Myers, RD; Peinado, JM | 1 |
| Busch, H; Satoh, K | 1 |
| Fujitaki, JM; Smith, RA; Yang, JC | 1 |
| Cozzone, AJ; Manai, M | 1 |
| Congote, LF | 1 |
| Capony, JP; Demaille, JG | 1 |
| Chang, WC; Chou, CK; Lee, ML; Lee, SC | 1 |
| De Groot, N; Galski, H; Hochberg, AA; Ilan, J | 1 |
| Martensen, TM | 1 |
| Stanley, P | 1 |
| Bachrach, HL; Baxt, B; Grubman, MJ; La Torre, JL | 1 |
| Feunteun, J; Kress, M; Resche-Rigon, M | 1 |
| Fiers, W; Fransen, L; Van Roy, F | 1 |
| Demigne, C; Fafournoux, P; Remesy, C | 1 |
| Kornfeld, R; Tollefsen, SE | 1 |
| Osawa, T; Tohyama, H; Tsuji, T; Tsunehisa, S; Watanabe, Y; Yamamoto, K | 1 |
| Bayer, R; Federiuk, CS; Shafer, JA | 1 |
| Carlstedt, I; Lindgren, H; Sheehan, JK; Ulmsten, U; Wingerup, L | 1 |
| Cagan, RH; Rhein, LD | 1 |
| Lennarz, WJ; Naider, F; Shenbagamurthi, P; Welply, JK | 1 |
| Derevitskaya, VA; Kochetkov, NK; Likhosherstov, LM; Martynova, MD | 1 |
| Ferrari, B; Pavia, AA | 1 |
| Majima, M; Matsue, H | 1 |
| Brown, SI; Chao, CC; Vergnes, JP | 1 |
| Kramer, MF; Smits, HL | 1 |
| Brickley-Parsons, D; Glimcher, MJ; Landis, WJ; Sanzone, CF | 1 |
| Marinetti, GV; Siani, M | 1 |
| Inouye, M; Inouye, S; Vlasuk, GP | 1 |
| Gray, TM; Matthews, BW | 1 |
| Bause, E | 1 |
| Holtzhauer, M; Sydow, H; Will, H | 1 |
| Hiken, JF; Lawrence, JC | 1 |
| Debusk, AG; Newton, RB; Sullivan, JL | 1 |
| Gazzano, H; Kowalski, A; van Obberghen, E | 1 |
| George, JR; Harrell, WK; Pine, L; Reeves, MW | 1 |
| Janjua, NA; MacGibbon, B; Metrakos, JD; Metrakos, K; van Gelder, NM | 1 |
| Babczinski, P | 1 |
| Allenza, P; Lessie, TG; Wong, HC | 1 |
| Glimcher, MJ; Kossiva, D; Reit, B | 1 |
| Evered, DF | 1 |
| Aubert, JP; Helbecque, N; Loucheux-Lefebvre, MH | 1 |
| Ellory, JC; Jones, SE; Young, JD | 1 |
| Wold, F | 1 |
| Dion, AS; Farwell, DC | 1 |
| Doi, H; Ibuki, F; Ideno, S; Kanamori, M | 1 |
| Clari, G; Michielin, E; Moret, V; Zen, F | 1 |
| Dill, K; Ferrari, B; Lacombe, JM; Pavia, AA | 1 |
| Beliveau, GP; Freedland, RA | 1 |
| Dempsey, WB | 1 |
| Robinson, JW; van Melle, G | 1 |
| Darai, G; Flügel, RM | 1 |
| Miller, EC; Ruhtenberg, M; Wagenknecht, C | 1 |
| Hasegawa, H; Honma, T; Miyagawa, M; Sato, M | 1 |
| Ohad, I; Owens, GC | 1 |
| Austic, RE; Davis, AT | 2 |
| Hölck, JP; Paulsen, H | 1 |
| Casini, A; Corti, P; Pogliani, L; Sabatini, G | 1 |
| Binette, JP; Hayashi, S; Kimura, A; Mao, SK; Schmid, K | 1 |
| Blouin, MJ; Gutowski, NJ; Ludwig, R; Noble, M; Pröschel, C | 1 |
| Gombart, AF; Hirano, A; Wong, TC | 1 |
| Furukawa, K; Goto, M; Hayashida, S; Semimaru, T | 1 |
| Hirata, D; Liu, Y; Miyakawa, T; Nakamura, T; Namba, H; Ohmoto, T | 1 |
| Mimnaugh, EG; Neckers, LM; Whitesell, L; Worland, PJ | 1 |
| Katsa, V; Knirel', IuA; Kochetkov, NK; Radzievska-Lebrekht, I; Vinogradov, EV | 1 |
| Bagrodia, S; Chackalaparampil, I; Shalloway, D | 1 |
| Chang, XB; Dulhanty, AM; Riordan, JR | 1 |
| Adams, V; McCabe, ER; Schieber, A | 1 |
| Barnard, GF; Chen, LB; Puder, M; Staniunas, RJ; Steele, GD | 1 |
| Feinstein, R; Hemi, R; Kanety, H; Karasik, A; Papa, MZ | 1 |
| Aperia, A; Celsi, G; da Cruz e Silva, EF; Durbeej, M; Ekblom, P; Laestadius, A; Svennilson, J | 1 |
| Ali, H; DuBose, RA; Haribabu, B; Richardson, RM; Snyderman, R; Tomhave, ED | 1 |
| Kunz, H; Schultz, M | 1 |
| Langdon, C; Polt, R; Ramza, J; Szabó, L | 1 |
| Braselmann, S; McCormick, F | 1 |
| Di Noia, JM; Frasch, AC; Sánchez, DO | 1 |
| Leberer, E; Thomas, DY; Whiteway, M; Wu, C | 1 |
| Brugnera, E; Georgiev, O; Müller, HP; Radtke, F; Schaffner, W | 1 |
| Burgess, JW; Stanley, KK; Zehavi-Feferman, R | 1 |
| Capp, E; Coghlan, M; Galante, P; Häring, HU; Kellerer, M; Kroder, G; Mosthaf, L; Mühlhöfer, A; Siddle, K | 1 |
| Barry, PH; Cunningham, AM; French, PW; Pierce, KD; Rajendra, S; Schofield, PR; Vandenberg, RJ | 1 |
| Goedert, M; Jakes, R; Vanmechelen, E | 1 |
| Berggren, PO; Honkanen, RE; Sjöholm, A | 1 |
| Gupta, SK; Hassel, T; Singh, JP | 1 |
| Connell, TD; Holmes, RK | 1 |
| Ando, S; Furutsuka, D; Ikebe, M; Zhou, ZH | 1 |
| Clark, EA; Krebs, EG; Licciardi, KA; Meier, KE; Valentine, MA | 1 |
| Citovsky, V; McLean, BG; Zambryski, P; Zupan, JR | 1 |
| Crovello, CS; Furie, B; Furie, BC | 1 |
| Hotta, K; Ishihara, K; Ohara, S | 1 |
| Blenis, J; Chen-Kiang, S; Li, HC; Schindler, C; Zhang, X | 1 |
| Desdouits, F; Girault, JA; Greengard, P; Siciliano, JC | 1 |
| Ilg, T; Lottspeich, F; Overath, P; Wiese, M | 1 |
| Gomi, S; Homma, M; Imae, Y; Iwama, T; Kawagishi, I | 1 |
| Hase, T; Kambayashi, J; Mori, T; Murata, K; Okuyama, M; Sakon, M | 1 |
| Bartley, T; Delorme, E; Derby, P; Elliott, S; Hunt, R; Lorenzini, T; Parker, V; Rohde, MF; Stoney, K | 1 |
| Bielfeldt, T; Bock, K; Meldal, M; Paulsen, H; Peters, S | 1 |
| Lauzé, E; Luca, FC; Schutz, AR; Stoelcker, B; Weiss, E; Winey, M | 1 |
| Atreya, CD; Nakhasi, HL; Singh, NK | 1 |
| Chou, TY; Dang, CV; Hart, GW | 1 |
| Colyer, J; Drago, GA | 1 |
| Komano, T; Miyashita, K; Satoh, N; Utsumi, R; Utsumi, T | 1 |
| Chou, KC; Kézdy, FJ; Poorman, RA; Zhang, CT | 1 |
| Bhavanandan, VP; DiIulio, NA | 1 |
| Song, JS; Yang, SD | 1 |
| Offer, G; Sessions, R | 1 |
| Aggarwal, BB; Chaturvedi, MM; Darnay, BG; Singh, S | 1 |
| Carman, GM; Yang, WL | 1 |
| Terrian, DM; Ways, DK | 1 |
| Harris, RA; Klein, RL; Mihic, SJ; Wafford, KA; Whiting, PJ | 1 |
| Lea, S; Stuart, D | 1 |
| Gooley, AA; Williams, KL | 1 |
| Carbon, J; Jiang, W; Lim, MY; Martin, GS; Thorner, J; Yoon, HJ | 1 |
| Bodwell, JE; Hu, JM; Munck, A; Orti, E | 1 |
| Heller, A; Isakov, N; Ofir, R; Rager-Zisman, B; Salzberg, S; Segev, Y; Udem, S; Weinstein, Y; Wolfson, M | 1 |
| Fujii, J; Ikeda, Y; Meister, A; Smith, TK; Taniguchi, N | 1 |
| Castagné, V; Finot, PA; Maire, JC | 1 |
| Cowman, AF; Lim, AS | 1 |
| Ahrens, F; Mosenthin, R; Sauer, WC | 1 |
| Haas, M; Jost, E | 1 |
| Lewis, RE; Sanderson, SD; Volle, DJ | 1 |
| Dell, KR; Engel, JN | 1 |
| Eckhart, W; Schönthal, A; Srinivas, S | 1 |
| Garg, HG; Kunz, H; von dem Bruch, K | 1 |
| Langer, M; Lieber, A; Rétey, J | 1 |
| Baccara, MT; Grigorescu, F; Renard, E; Rouard, M | 1 |
| Coghlan, MP; Pillay, TS; Siddle, K; Tavaré, JM | 1 |
| Dobrowolska, G; Krebs, EG; Li, D; Lozeman, FJ; Marin, O; Meggio, F; Pinna, LA | 1 |
| Ariga, H; Iwata, K; Nagasawa, S; Seya, T; Ueda, S | 1 |
| Goldsbrough, PB; Hasegawa, PM; Singh, NK; Smeda, RJ; Weller, SC | 1 |
| Lin, RT; Newman, EB; Shao, Z | 1 |
| Wüthrich, K | 1 |
| Polt, R; Szabó, L | 1 |
| Blümich, B; Just, M; Mitze, M; Speckter, H; Thelen, M; Trömel, U | 1 |
| Eissenberg, JC; Ge, YW; Hartnett, T | 1 |
| Belduz, AO; Glasgow, J; Harman, JG; Lee, EJ; Leu, SF | 1 |
| Cotecchia, S; Diviani, D; Lattion, AL | 1 |
| Kurosky, A; Miller, BT; Rogers, ME; Smith, JS | 1 |
| Kennelly, PJ | 1 |
| Curran, TP; Riordan, JF; Shapiro, R | 1 |
| Fedele, E; Foster, AC | 1 |
| Chevaillier, P | 1 |
| Cleary, DL; Guido, DM; Kubiak, TM; Martin, RA; Zurcher-Neely, HA | 1 |
| Blumenthal, EJ; Malkinson, AM; Miller, AC; Stein, GH | 1 |
| Grémeaux, T; Le Marchand-Brustel, Y; Tanti, JF; van Obberghen, E | 1 |
| Inglese, J; Koch, WJ; Lefkowitz, RJ; Premont, RT | 1 |
| Guan, KL; Zheng, CF | 1 |
| Harada, M; Misono, H; Nagasaki, S; Nagata, S; Packdibamrung, K | 1 |
| Summers, J; Yu, M | 1 |
| Capeau, J; Caron, M; Cherqui, G; Picard, J; Reynet, C; Wicek, D | 1 |
| Bosron, WF; Carr, LG; Davis, GJ; Hurley, TD; Li, TK | 1 |
| Gotoh, Y; Hattori, S; Ishikawa, M; Iwamatsu, A; Kosako, H; Matsuda, S; Nishida, E; Takenaka, K | 1 |
| Blaber, M; Gassner, N; Heinz, DW; Lindstrom, JD; Matthews, BW; Xu, J | 1 |
| Baciou, L; Bylina, EJ; Sebban, P | 1 |
| Hirano, H; Kajiwara, H; Komatsu, S; Takagi, Y; Tsunasawa, S | 1 |
| Agrwal, N; Eckhardt, AE; Hill, RL; Stevens, RD; Wang, Y | 1 |
| Lombardini, JB | 1 |
| Galacteros, F; Gilsanz, F; Kister, J; Promé, D; Wajcman, H | 1 |
| Castagné, V; Finot, PA; Maire, JC; Moënnoz, D | 1 |
| Bornaes, C; Holmberg, S; Ignjatovic, MW; Kielland-Brandt, MC; Schjerling, P | 1 |
| O'Connell, BC; Tabak, LA | 1 |
| Ekman, P; Eller, M; Engström, L; Järv, J; Ragnarsson, U; Toomik, R | 1 |
| Peraldi, P; Van Obberghen, E | 1 |
| Merbs, SL; Nathans, J | 1 |
| Barford, D; Keller, JC | 1 |
| Shen, F; Wu, AM; Wu, JH | 1 |
| Evan, G; Fisher, C; Littlewood, T; Pulverer, BJ; Vousden, K; Woodgett, JR | 1 |
| Basa, LJ; Glushka, J; Harris, RJ; Ling, VT; Smith, KJ; Spellman, MW; van Halbeek, H | 1 |
| Jaeger, E; Jung, G; Metzger, J; Oberthür, W; Remmer, HA; Rücknagel, KP; Schäfer, W; Sonnenbichler, J; Zetl, I | 1 |
| Henly, C; Marriott, MS; Nassau, PM; Weston, A | 1 |
| Hagen, FK; Tabak, LA; Van Wuyckhuyse, B | 1 |
| Decker, SJ; Pang, L; Saltiel, AR | 1 |
| Cantwell, JS; Kennelly, PJ; Leng, J; Oxenrider, KA; Zhao, N | 1 |
| Newman, EB; Shao, Z | 1 |
| Moorthy, RK; Thorley-Lawson, DA | 1 |
| Davis, RJ; Gupta, S; Seth, A | 1 |
| Baggio, B; Bordin, L; Clari, G; Gambaro, G; Moret, V | 1 |
| Gusev, NB; Marston, SB; Redwood, CS | 1 |
| Battey, JF; Benya, RV; Fathi, Z; Jensen, RT | 1 |
| Breslow, E; Huang, H; LaBorde, T | 1 |
| Dailey, D; Lim, MY; Martin, GS; Thorner, J | 1 |
| Arioka, M; Imahori, K; Ishiguro, K; Kato, R; Sato, K; Tsukamoto, M; Uchida, T | 1 |
| Deprun, C; Lamthanh, H; Ménez, A; Roumestand, C | 1 |
| Shaner, D; Singh, BK; Szamosi, I | 1 |
| Fukuda, T; Imai, Y; Komori, M; Kusunose, E; Kusunose, M; Nakamura, M; Satouchi, K | 1 |
| Lameh, J; Moro, O; Sadée, W | 1 |
| Kim, T; Park, I; Payne, NS; Shin, J; Strominger, JL; Walsh, CT; Winkler, DG | 1 |
| Fukushima, K; Hayashi, Y; Ohya, Y; Seto, T; Shikata, Y; Yoshida, Y; Yoshimatsu, K | 1 |
| Caelles, C; Hennemann, H; Karin, M | 1 |
| Jackson, RL; Perrault, J; Spadafora, D | 1 |
| Combettes, M; Ferre, P; Issad, T | 1 |
| Dooley, S; Engel, M; Lacombe, ML; Seib, T; Theisinger, B; Véron, M; Welter, C | 1 |
| Ahmadian, MR; Blechschmidt, B; Kreutzer, R; Sprinzl, M | 1 |
| Hara, T; Hatanaka, M; Matsumoto, M; Semba, T; Seya, T; Suzuki, Y | 1 |
| Bause, E; Breuer, W; Peters, S | 1 |
| Gomme, PT; Hearn, MT; Keah, HH; Stanton, PG; Thompson, PE | 1 |
| Döring, F; Illenberger, S; Mandelkow, EM; Preuss, U | 1 |
| Liu, JW; Mamidi, M; Walker, AM; Wang, YF | 1 |
| Amagasa, T; Ichijo, H; Miyazono, K; Nishitoh, H; Saitoh, M; Takagi, M | 1 |
| Bhavanandan, VP; Zhu, Q | 1 |
| Dill, K; Olson, JD | 1 |
| Cox, K; Gienapp, I; Javed, NH; Whitacre, CC | 1 |
| Hammer, VA; Morris, JG; Rogers, QR | 1 |
| Demoise, DC; Lee, VM; Merrick, SE | 1 |
| Barnes, JA; Gomes, AV | 1 |
| Mothe, I; Van Obberghen, E | 1 |
| Manley, JL; Zhao, W | 1 |
| Clausen, H; Gram, GJ; Hansen, JE; Jansson, B; Nielsen, JO; Olofsson, S | 1 |
| Crimmins, DL; Joyal, JL; Sacks, DB; Thoma, RS | 1 |
| Colyer, J; Jackson, WA | 1 |
| Demuth, HU; Diefenthal, T; Grosche, G; Kaspari, A; Schierhorn, A | 1 |
| Frank, JS; Hryshko, LV; Matsuoka, S; Nicoll, DA; Philipson, KD | 1 |
| Brovtsyna, NB; Gmiro, VE; Gorbunova, OB; Lukomskaya, NY; Magazanik, LG; Serduk, SE; Tikhonov, DB; Zhorov, BS | 1 |
| Décout, JL; Fieschi, F; Fontecave, M; Nivière, V | 1 |
| Fromentin, G; Nicolaidis, S | 1 |
| Kasai, T; Kiriyama, S; Tanaka, T | 1 |
| Kosk-Kosicka, D; Li, Z; Lopez, MM; Sacks, DB | 1 |
| Alibhai, M; Chow, AM; Paoni, NF | 1 |
| Li, LI; Mathews, LS; Willis, SA; Zimmerman, CM | 1 |
| Barnes, S; Comer, FI; Greis, KD; Hart, GW; Hayes, BK; Kirk, M; Lowary, TL | 1 |
| Buchwald, AB; Kreuzer, H; Meyer, T; Unterberg, C | 1 |
| Barford, D | 1 |
| Rechsteiner, M; Rogers, SW | 1 |
| Kissinger, CR; Parge, HE; Villafranca, JE | 1 |
| Chae, SW; Cho, KP; Kwak, YG; Park, SK | 1 |
| Jonas, EA; Kaczmarek, LK | 1 |
| Jockusch, BM; Rüdiger, M; Schwienbacher, C | 1 |
| Bar-Sagi, D; Corbalan-Garcia, S; Degenhardt, KR; Yang, SS | 1 |
| Kumashiro, S; Kurumaji, A; Semba, J; Toru, M; Watanabe, A | 1 |
| Holmberg, S; Schjerling, P | 1 |
| Brandin, E; Branton, D; Chan, EP; Lue, RA | 1 |
| Hosono, R; Kimoto, M; Ogawa, H; Sassa, T | 1 |
| Adomeit, A; Boehmer, A; Boehmer, FD; Graness, A; Kovalenko, M; Liebmann, C; Nürnberg, B; Steinmetzer, T; Wetzker, R | 1 |
| Artçanuthurry, V; Grelac, F; Levy-Tolédano, S; Maclouf, J; Martin-Cramer, E | 1 |
| Bohr, H; Engelbrecht, J; Hansen, JE; Lund, O; Nielsen, JO | 1 |
| Aronson, NN | 1 |
| Bordin, L; Clari, G; Colombatto, S; Grillo, MA; Testore, G; Toninello, A; Vargiu, C | 1 |
| Charo, IF; Coughlin, SR; Franci, C; Gosling, J; Tsou, CL | 1 |
| Kernodle, DS; Tummuru, MK; Voladri, RK | 1 |
| Ullrich, A; Vogel, W | 1 |
| de Cingolani, GC; Mattiazzi, A; Mundiña-Weilenmann, C; Ortale, M; Vittone, L | 1 |
| Londos, C; Rondinone, CM; Smith, UP; Zarnowski, MJ | 1 |
| Avila, J; Moreno, FJ; Muñoz-Montaño, JR | 1 |
| Alessi, DR; Andjelkovic, M; Caudwell, B; Cohen, P; Cron, P; Hemmings, BA; Morrice, N | 1 |
| Bishop, GA; Grose, C; Olson, JK | 1 |
| Biron, KK; Chu, L; Coen, DM; He, YS; He, Z; Kim, Y; Ohmstede, C | 1 |
| Böhm, SK; Bunnett, NW; Grady, EF; Khitin, LM; Payan, DG; Smeekens, SP | 1 |
| Al-Hasani, H; Eisermann, B; Klein, HW; Koenen, M; Magg, C; Meyer, HE; Müller-Wieland, D; Passlack, W; Tennagels, N | 1 |
| Bennett, GS; Quintana, R | 1 |
| Fleurent, M; Gingras, AC; Meloche, S; Sonenberg, N | 1 |
| Hall, RA; Soderling, TR | 1 |
| Anderson, MM; Hazen, SL; Heinecke, JW; Hsu, FF | 1 |
| Afshar, M; Cavadore, JC; Dorée, M; Labbé, JC; Martin, F; Martinez, AM | 1 |
| da-Costa-Maia, JC; da-Silva, AM; Terenzi, HF; Zapella, PD | 1 |
| Mufson, RA | 1 |
| Bazarsky, E; Blagerman, S; Hunter, T; Ofir, R; Rager-Zisman, B; Weinstein, Y; Wolfson, M | 1 |
| Cunningham, A; Lazo, JS; Rice, RL; Wipf, P | 1 |
| Chow, LP; Kamo, M; Kawakami, T; Miyazaki, K; Takamoto, K; Tsugita, A; Ueno, Y | 1 |
| McFadden, BA; Rehman, A | 2 |
| Himi-Nakamura, E; Hosoya, H; Iwata, K; Komatsu, S; Sakai, H; Tezuka, A; Totsukawa, G; Yazaki, K | 1 |
| Anderton, BH; Gibb, GM; Reynolds, CH; Utton, MA; Yates, A | 1 |
| Czernik, AJ; Gandy, SE; Greengard, P; Isohara, T; Lim, GS; Nairn, AC; Oishi, M; Suzuki, T | 1 |
| Gerken, TA; Owens, CL; Pasumarthy, M | 1 |
| Alessi, DR; Cohen, P; Downes, CP; Gaffney, PR; Holmes, AB; James, SR; Reese, CB | 1 |
| Greene, NM; Newton, AC; Williams, DS | 1 |
| Chang, TH; Hu, VW; Laird, DW; Xie, H | 1 |
| Hirano, H; Komatsu, S; Tsunasawa, S | 1 |
| Chin, KC; Li, GG; Ting, JP | 1 |
| Chen, H; Kasturi, L; Shakin-Eshleman, SH | 1 |
| Austic, RE; Davis, AJ | 1 |
| Osawa, S; Sports, CD; Weiss, ER; Zhang, L | 1 |
| Chen, RH; Derynck, R; Feng, XH; Griswold-Prenner, I; Lawler, S; Maruoka, EM; Turck, CW | 1 |
| Hanscombe, O; O'Hare, P; O'Reilly, D | 1 |
| Dabrosin, C; Hallström, A; Hammar, M; Ungerstedt, U | 1 |
| Moitra, J; Szilák, L; Vinson, C | 1 |
| Jenab, S; Morris, PL | 1 |
| Ekino, K; Furukawa, K; Goto, M | 1 |
| Lee, VM; Merrick, SE; Trojanowski, JQ | 1 |
| Abe, M; Funaba, M; Iriki, T | 1 |
| Ferreri, NR; Mahboubi, K; Young, W | 1 |
| Ichishima, E; Nomura, K; Shintani, T | 1 |
| Benito, M; Lorenzo, M; Teruel, T; Valverde, AM | 1 |
| Yarden, O; Yatzkan, E | 1 |
| Chung, CH; Kang, MS; Seol, JH; Seong, IS; Shim, YK; Yoo, SJ | 1 |
| Bockus, BJ; Chatterjee, A; Gjørup, OV; Schaffhausen, BS | 1 |
| Ha, KS; Jung, HI; Kang, KW; Park, YM; Shin, I | 1 |
| Gulick, AM; Holden, HM; Thoden, JB | 1 |
| DeLoach, JR; Hume, ME; Nisbet, DJ | 1 |
| Hayashi, F; Nishikawa, T; Takahashi, K | 1 |
| Chastain, CJ; Chollet, R; Lee, ME; Moorman, MA; Shameekumar, P | 1 |
| Bakos, E; Goodfellow, HR; Higgins, CF; Müller, M; Sarkadi, B; Szabó, K; Váradi, A; Welker, E | 1 |
| Baker, DH; Edwards, HM; Fernandez, SR; Parsons, CM | 1 |
| Kreienkamp, HJ; Meyerhof, W; Richter, D; Roth, A | 1 |
| Belloni, E; Gaudenz, K; Muenke, M; Roessler, E; Scherer, SW; Tsui, LC; Vargas, F | 1 |
| George, SR; O'Dowd, BF; Pak, Y | 1 |
| Lin, Q; Resnick, RJ; Shalloway, D; Taylor, SJ | 1 |
| Cronin, CN | 1 |
| Aman, MJ; Henkart, PA; Leonard, WJ; Nakajima, H; Noguchi, M; Sarin, A; Shores, EW | 1 |
| Felbor, U; Schilling, H; Weber, BH | 1 |
| Bruneau, N; Fisher, EA; Lombardo, D; Nganga, A | 1 |
| Bertin, B; Capeyrou, R; Corbani, M; Emorine, LJ; Lepage, JF; Riond, J | 1 |
| Pegg, AE; Stanley, BA; Tekwani, BL; Xiong, H | 1 |
| Baldwin, AN; Le Bivic, A; Le Gall, AH; Monlauzeur, L; Rodriguez-Boulan, E; Yeaman, C | 1 |
| Sfeir, C; Veis, A; Wu, CB | 1 |
| Alessi, DR; Andjelković, M; Cohen, P; Cron, P; Fernandez, A; Frech, M; Hemmings, BA; Lamb, NJ; Lucocq, JM; Meier, R | 1 |
| Ratcliffe, MJ; Rubin, LL; Staddon, JM | 1 |
| Chao, H; Davies, PL; Hodges, RS; Houston, ME; Kay, CM; Loewen, MC; Sönnichsen, FD; Sykes, BD | 1 |
| Freestone, P; Norris, V; Nyström, T; Trinei, M | 1 |
| Brunn, GJ; Fadden, P; Haystead, TA; Lawrence, JC | 1 |
| Jordan, P; Karess, R | 1 |
| Doege, H; Holman, GD; Joost, HG; Monser, V; Ohnimus, H; Schürmann, A | 1 |
| Arbel, A; Elgavish, S; Ginzberg, D; Glick, D; Grifman, M; Shaanan, B; Soreq, H | 1 |
| Alessi, DR; Avruch, J; Kozlowski, MT; Morrice, N; Weng, QP | 1 |
| Avruch, J; Caudwell, FB; Cohen, P; Dalby, KN; Morrice, N | 1 |
| Demachi, Y; Furuya, N; Imanari, T; Komoriya, S; Toida, T; Toyoda, H | 1 |
| Kormanec, J; Nováková, R; Sevcíková, B | 1 |
| Potter, LR | 1 |
| Backer, JM; McIlroy, J; Orr, GA; Rordorf-Nikolic, T; Yu, J; Zhang, Y | 1 |
| Borel, C; Hantz, O; Kay, A; Sunyach, C; Trepo, C | 1 |
| Jacks, T; McClatchey, AI; Shaw, RJ | 1 |
| Best, JM; Bosma, T; Johnstone, P; Sanders, PG; Whitby, JE | 1 |
| Hunter, T; Potter, LR | 4 |
| Amrhein, N; Grill, E; Leube, MP | 1 |
| Perler, FB | 1 |
| Biernat, J; Godemann, R; Illenberger, S; Mandelkow, E; Mandelkow, EM; Zheng-Fischhöfer, Q | 1 |
| Bernhardt, A; Fischer, G; Lu, KP; Rahfeld, JU; Reimer, U; Schutkowski, M; Shen, M; Zhou, XZ | 1 |
| Nowak, W | 1 |
| Lin, A; Maes, M; Scharpé, S; Vandoolaeghe, E; Verkerk, R | 1 |
| Kasturi, L; Mellquist, JL; Shakin-Eshleman, SH; Spitalnik, SL | 1 |
| Balch, C; Campos, B; Dedman, JR; Head, JF; Li, CW; Mealy, TR; Mo, YD; Retzinger, G; Seaton, BA; Swairjo, MA | 1 |
| Russell, P; Shiozaki, K; Shiozaki, M | 1 |
| Ammerer, G; Bourlat, S; Cross, FR; Gartner, A; Jeoung, DI; Jovanović, A | 1 |
| Hino, Y; Kasuga, M; Kikkawa, U; Kitamura, T; Konishi, H; Kuroda, S; Maeda, T; Matsumoto, M; Ogawa, W; Sakaue, H; Takata, M | 1 |
| Karsenty, G; Mahajan, M; McLarren, KW; Stifani, S; Thirunavukkarasu, K | 1 |
| Castelain, S; Duverlie, G; Eb, F; Izopet, J; Jaillon, O; Khorsi, H; Lunel, F; Penin, F; Wychowski, C | 1 |
| Klessig, DF; Zhang, S | 1 |
| Kamo, M; Kawakami, T; Miyazaki, K; Nozawa, T; Shen, R; Takayama, M; Tsugita, A | 1 |
| Braus, GH; Krappmann, S; Schnappauf, G | 1 |
| Brown, MC; Perrotta, JA; Turner, CE | 1 |
| Andersson, AM; Holmberg, L; Kornfält, R; Kristoffersson, AC; Lannefors, L; Schaedel, C | 1 |
| Cismowski, MJ; Li, E; Stone, DE | 1 |
| Coleman, CS; del Valle, AE; Feith, D; Matés, JM; Olmo, MT; Pegg, AE; Sánchez-Jiménez, F; Urdiales, JL | 1 |
| Furuya, S; Hirabayashi, Y; Kasama, T; Mitoma, J | 1 |
| Prüss, BM | 1 |
| Acosta, MC; Giraldo, LE; Krogstad, DJ; Labrada, LA; Montenegro-James, S; Praba, A; Saravia, NG | 1 |
| Downie, S; Patel, A; Rennie, MJ; Reynolds, N; Smith, K | 1 |
| Ahmed, NN; Bellacosa, A; Chan, TO; Datta, K; Feng, J; Malstrom, S; McCormick, F; Stokoe, D; Tsichlis, P | 1 |
| Cooper, JA; Dohmae, N; Ito, Y; Kainosho, M; Kigawa, T; Laue, ED; Takio, K; Terada, T; Yabuki, T; Yokoyama, S | 1 |
| Kamo, M; Tsugita, A | 1 |
| Bieker, JJ; Chen, X; Ouyang, L | 1 |
| Grundke-Iqbal, I; Iqbal, K; Kabat, J; Novak, M; Sengupta, A; Wu, Q | 1 |
| Nelson, JG; Olefsky, JM; Reichart, DR; Staubs, PA | 1 |
| Dubery, IA; Frylinck, L | 1 |
| Demonacos, C; Kanazir, D; Krstic-Demonacos, M; Pocuca, N; Ruzdijic, S | 1 |
| Hisanaga, S; Hotani, H; Ishiguro, K; Itoh, TJ; Kishimoto, T; Saito, T; Uchida, T; Wada, Y | 1 |
| Iijima, H; Ito, MR; Kawarabayasi, Y; Magoori, K; Miyazawa, M; Nose, M; Sakai, J; Suzuki, H; Yamamoto, TT | 1 |
| Atkinson, JP; Leung, MK; Liszewski, MK | 1 |
| Takeda-Shitaka, M; Umeyama, H | 1 |
| Emmett, MR; Hendrickson, CL; Li, W; Marshall, AG; Wang, F; Wu, L; Zhang, YL; Zhang, ZY | 1 |
| Adachi, K; Hirata, Y; Kiuchi, K | 1 |
| Bouin, AP; Fuchs, A; Grandvaux, N; Vignais, PV | 1 |
| Avila, A; González-Mariscal, L; Islas, S; Perez-Moreno, M; Sanchez, S | 1 |
| Chun, KT; Wek, RC; Yang, R | 1 |
| Jaffe, H; Pant, HC | 1 |
| Doré, JJ; Edens, M; Garamszegi, N; Leof, EB | 1 |
| Hutchinson, EG; Sessions, RB; Thornton, JM; Woolfson, DN | 1 |
| Ananthanarayanan, M; Anwer, MS; Meier, PJ; Mukhopadhyay, S; Stieger, B; Suchy, FJ | 1 |
| Clark, BJ; Stocco, DM | 1 |
| Rusnak, F; Todorovic, S; Wengenack, NL; Yu, L | 1 |
| Catt, KJ; Hunyady, L; Jayadev, S; Mihalik, B; Olivares-Reyes, JA; Smith, RD | 1 |
| Sawers, G | 1 |
| Kinzel, V; Lindemann, A; Reed, J; Tholey, A | 1 |
| Golabek, AA; Kaczmarski, A; Kaczmarski, W; Kida, E; Michalewski, MP; Wisniewski, KE | 2 |
| Duus, KM; Grose, C; Peng, J; Price, DH; Ye, M | 1 |
| Akimoto, Y; Hart, GW; Hirano, H; Kreppel, LK | 1 |
| Kaiser, R; Metzka, L | 1 |
| Jorgensen, PL; Nielsen, JM; Pedersen, PA; Rasmussen, JH | 1 |
| Kaziro, Y; Nishida, K; Satoh, T | 1 |
| Saeki, K; Takaku, F; Yuo, A | 1 |
| Caputi, A; Cattabeni, F; Cimino, M; Di Luca, M; Gardoni, F; Pastorino, L | 1 |
| Chen, ZP; Kemp, BE; Michell, BJ; Mitchelhill, KI; Ortiz de Montellano, PR; Power, DA; Rodriguez-Crespo, I; Stapleton, D; Witters, LA | 1 |
| Charlier, D; Delannay, S; Piérard, A; Stalon, V; Tricot, C; Villeret, V | 1 |
| Becker, S; Klenk, HD; Lötfering, B; Mühlberger, E; Tamura, T | 1 |
| Milner-White, EJ; Wan, WY | 1 |
| Grafstrom, RH; Hoess, RH; Pan, W | 1 |
| Greengard, P; Horiuchi, A; Huang, HB; Li, HC; Nairn, AC; Shih, SR; Tsay, HJ; Watanabe, T | 1 |
| Colley, KJ; Ma, J; Qian, R; Simonovic, M | 1 |
| Marin, O; Meggio, F; Pinna, LA | 1 |
| Qian, H; Vijayakumar, M; Zhou, HX | 1 |
| Brannock, MT; Robinson, PR; Weng, K | 1 |
| Brodbeck, D; Cron, P; Hemmings, BA | 1 |
| Cao, Z; Hiyama, A; Inoue, J; Kishimoto, K; Matsumoto, K; Ninomiya-Tsuji, J | 1 |
| Ekino, K; Furukawa, K; Goto, M; Kwon, I; Tsukamoto, M | 1 |
| Alving, K; Clausen, H; Gooley, AA; Hanisch, FG; Hassan, H; Müller, S; Paulsen, H; Peter-Katalinic, J; Zachara, N | 1 |
| Cohen, P; Kobayashi, T | 1 |
| Chase, DL; Feng, Y; Ferris, DK; Hodge, DR; Longo, DL; Palmieri, G | 1 |
| Connolly, BA; Evans, SJ; Maughan, WN; Shipstone, EJ | 1 |
| Wera, S | 1 |
| Matsumura, A; Rao, S; Simon, MC; Yoon, J | 1 |
| Alhenc-Gelas, F; Blaukat, A; Müller-Esterl, W; Pizard, A; Rajerison, RM | 1 |
| Marin, O; Pinna, LA; Proud, CG; Williams, DD | 1 |
| Elsliger, MA; Hanson, GT; Kallio, K; Remington, SJ; Wachter, RM | 1 |
| Anagnostopoulos, I; Fechner, H; Haack, A; Merklein, F; Poller, W; Schneider-Rasp, S; Wang, H; Weidinger, S | 1 |
| Cubizolles, F; Giet, R; Le Guellec, K; Prigent, C; Uzbekov, R | 1 |
| Bjorkoy, G; Bruun, JA; Holm, T; Johansen, T; Mikkola, I | 1 |
| Bartel, S; Hempel, P; Karczewski, P; Krause, EG; Kuschel, M; Schlegel, WP | 1 |
| Accili, D; Nakae, J; Park, BC | 1 |
| Hurley, TD; Weiner, H | 1 |
| Cichy, SC; Cohen, P; Guo, S; Rena, G; Unterman, TG | 1 |
| Mathews, MB; Pe'ery, T; Ramanathan, Y; Reza, SM; Young, TM | 1 |
| Craig, AG; Hunter, T; Jiang, W; Ruffner, H; Verma, IM | 1 |
| Andjelković, M; Cron, P; Hemmings, BA; Maira, SM; Parker, PJ | 1 |
| Beachy, RN; Hosokawa, D; Kawakami, S; Okada, Y; Padgett, HS; Watanabe, Y | 1 |
| Boersma, A; Briand, G; Degand, P; Demeyer, D; Hennebicq, S; Richet, C; Soudan, B; Tetaert, D | 1 |
| Behn-Krappa, A; Newton, AC | 1 |
| Kouzarides, T; Vandel, L | 1 |
| Arsequell, G; Elliott, T; Haurum, JS; Høier, IB; Neefjes, J; Neisig, A; Valencia, G; Zeuthen, J | 1 |
| Derrien, M; Grubisha, O; Khanna, M; Punjabi, A; Traktman, P | 1 |
| Dang-Lawson, M; Duronio, V; Gold, MR; Krebs, DL; Matsuuchi, L; Roth, RA; Santos, L; Scheid, MP | 1 |
| Chung, C; Han, JM; Kim, JH; Kim, Y; Lee, SD; Lee, TG; Oh, YS; Park, JB; Park, SK; Ryu, SH; Suh, PG; Yoo, JS | 1 |
| Belcher, KL; Boxer, SG; Decatur, SM; Franzen, S; Rickert, PK | 1 |
| Cody, V; Queener, SF; Rosowsky, A | 1 |
| Carter-Su, C; Herrington, J; Rui, L | 1 |
| Martín de Ana, A; Martínez-A, C; Mellado, M; Rodríguez-Frade, JM; Vila-Coro, AJ | 1 |
| Brender, C; Brockdorff, J; Christensen, ST; Engel, AM; Geisler, C; Kaltoft, K; Leick, V; Nielsen, M; Odum, N; Rygaard, J; Skov, S; Svejgaard, A; Woetmann, A | 1 |
| Huang, XP; Messer, WS; Peseckis, SM; Williams, FE | 1 |
| Byerly, L; Gera, S | 1 |
| Bhaskar, KR; Hadzopoulou-Cladaras, M; LaMont, JT; Turner, BS | 1 |
| Cesaro, L; Marin, O; Meggio, F; Pagano, MA; Pinna, LA; Sarno, S | 1 |
| Dahlbäck, B; Nicolaes, GA; Villoutreix, BO | 1 |
| Carson, J; Schmidtke, LM | 1 |
| Campbell, DH; Daly, RJ; Sutherland, RL | 1 |
| Chakrabarty, AM; Kapatral, V; Mukhopadhyay, S; Xu, W | 1 |
| Dever, TE; Lu, J; O'Hara, EB; Romano, PR; Trieselmann, BA | 1 |
| Hoffmann, R; Metzger, S; Otvos, L; Spengler, B | 1 |
| Shu, CK | 1 |
| Chang, RP; Chen, DS; Chen, PJ; Chiang, BL; Mu, JJ; Wu, HL | 1 |
| Chen, J; Ho, CT | 1 |
| Bize, I; Brugnara, C; Buchbinder, G; Güvenç, B; Robb, A | 1 |
| Carafoli, E; Corti, C; James, P; Leclerc, E; Schmid, H; Vetter, S | 1 |
| Hemmings, BA; Hess, D; Millward, TA | 1 |
| Ichijo, H; Korsmeyer, SJ; Yamamoto, K | 1 |
| Kolega, J | 1 |
| Hara, K; Parekh, D; Parker, PJ; Yonezawa, K; Ziegler, W | 1 |
| Blom, N; Brunak, S; Gammeltoft, S | 1 |
| Colyer, J | 1 |
| Dumaz, N; Meek, DW; Milne, DM | 1 |
| Alvarez de la Rosa, D; Canessa, CM; Fejes-Tóth, G; Náray-Fejes-Tóth, A; Zhang, P | 1 |
| Elhammer, AP; Kézdy, FJ; Kurosaka, A | 1 |
| Gilbert, C; Naccache, PH; Rollet-Labelle, E | 1 |
| Pei, L | 1 |
| Buck, M; Chojkier, M; Hunter, T; Poli, V; van der Geer, P | 1 |
| Duronio, V; May, WS; McCubrey, JA; Mufson, A | 1 |
| Chen, J; Du, X; Gu, M; Sliva, D; Tsai, S; Yang, YC; Zhu, YX | 1 |
| Christian, FA; Jackson, RN; Tate, TM | 1 |
| Kanaho, Y; Watanabe, H | 1 |
| Eigel, A; Horst, J; Kramarov, V; Lemmens, M; Okladnova, O; Syagailo, Y; Wilke, K | 1 |
| Gordon-Krajcer, W; Ksiezak-Reding, H; Yang, L | 1 |
| Bienkiewicz, EA; Lumb, KJ | 1 |
| Minnie, LJ; Terblanche, SE; van der Westhuizen, BM | 1 |
| Adams, JP; Anderson, AE; Cook, RG; Pfaffinger, PJ; Qian, Y; Sweatt, JD | 1 |
| Bristol, JR; Chen, G; Fitzgibbon, MJ; Pazhanisamy, S; Porter, MD | 1 |
| Corzo, N; del Castillo, MD; Olano, A; Sanz, ML | 1 |
| Wang, HL | 1 |
| Barrientes, S; Cooke, C; Goodrich, DW | 1 |
| Hara, J; Inokuchi, N; Irie, M; Itagaki, T; Iwama, M; Kobayashi, H; Koyama, T; Ohgi, K | 1 |
| Chang, SJ; Chen, JY; Chen, MR; Huang, H | 1 |
| Newton, AC; Toker, A | 1 |
| de Groot, HJ; Förster, H; Oschkinat, H; Pauli, J; van Rossum, B | 1 |
| Lallès, JP; Montagne, L; Toullec, R | 1 |
| Booth, FW; Flück, M; Waxham, MN | 1 |
| Fang, S; Mo, W; Satomi, Y; Shimonishi, Y; Takao, T | 1 |
| Angelova, K; Narayan, P; Puett, D; Simon, JP | 1 |
| de la Luz Ibarra, M; García, EJ; Jay, D; Lara, JE; Medina, MA | 1 |
| Ishihara, H; Itoh, T; Oka, Y; Shibasaki, Y; Takenawa, T | 1 |
| Fadden, P; Haystead, TA; Lawrence, JC; Mothe-Satney, I; Yang, D | 1 |
| Reinhardt, J; Wolff, T | 1 |
| Lesslauer, W; Mary, JL; Tomás-Zuber, M | 1 |
| Brunati, AM; Donella-Deana, A; Marin, O; Pinna, LA; Ruzzene, M; Sarno, S | 1 |
| Goldberg, AL; Kisselev, AF; Songyang, Z | 1 |
| Eswar, N; Ramakrishnan, C | 1 |
| D'Ascenzo, M; Martin, GB; Sessa, G | 1 |
| Longnecker, R | 1 |
| Cheng, H; Hagemann, D; Kuramochi, T; Kuschel, M; Xiao, RP; Zhu, W | 1 |
| Taylor, MK; Uhler, MD | 1 |
| Williams, BR; Xu, Z | 1 |
| Benecke, H; Drenckhan, M; Klein, HH; Schütt, M | 1 |
| Akkerman, JW; Eybrechts, K; Kroner, C | 1 |
| Blanc, S; Héricourt, F; Jupin, I; Redeker, V | 1 |
| Le Caer, JP; Manceau, V; Maucuer, A; Sobel, A | 1 |
| Grüning, C; Rehder, D | 1 |
| Kolter, R; Zinser, ER | 1 |
| Müller, R; Reth, M; Wienands, J | 1 |
| Content, J; De Wit, L; Parmentier, B; Peirs, P | 1 |
| Fang, NX; Fernando, GJ; Frazer, IH | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Chung, J; Kim, D; Kim, JW; Kim, S; Koh, H; Lee, KH | 1 |
| Cheng, A; Kaldis, P; Solomon, MJ | 1 |
| Lukat-Rodgers, GS; Rodgers, KR; Rusnak, F; Wengenack, NL | 2 |
| Barber, MJ; Pollock, VV | 1 |
| Geyer, R; Hintz, M; Hobom, G; Li, J; Linder, M; Liu, Q | 1 |
| Hintz, M; Linder, D; Loukas, A; Maizels, RM; Mullin, NP; Parkinson, J; Tetteh, KK | 1 |
| Lazo, PA; Lopez-Borges, S | 1 |
| Erickson, LJ; Kouhen, OM; Law, PY; Loh, HH; Solberg, J; Wang, G | 1 |
| Davare, MA; Hell, JW; Horne, MC | 1 |
| Kennedy, MJ; Lopes, H; Moura, I; Moura, JJ; Pereira, AS; Rusnak, F; Tavares, P; Wengenack, NL | 1 |
| Karlsson, AM; Lerner, MR; Lundström, I; Svensson, SP; Unett, D | 1 |
| Bachmaier, R; Chen, MH; Citovsky, V; Ghoshroy, S; Waigmann, E | 1 |
| Jakubowski, H | 1 |
| Kar, S; Quirion, R; Zheng, WH | 2 |
| Wang, Z; Yang, ZQ | 1 |
| Dong, LQ; Liu, F; Ramos, FJ; Riojas, RA; Wick, MJ | 1 |
| Boscoboinik, D; Jannin, B; Latruffe, N; Motojima, K; Passilly-Degrace, P | 1 |
| Ali-Osman, F; Mullapudi, SR; Shou, J; Srivenugopal, KS | 1 |
| Bartel, S; Burrell, K; Cochrane, A; Jalali, H; Karczewski, P; Kaumann, A; Krause, EG; Molenaar, P; Pohlner, P; Vetter, D | 1 |
| Hecht, D; Ho, SW; Hoffman, MP; Jung, DW; Kleinman, HK; O'Connell, BC | 1 |
| Cress, WD; Hu, X; Zhong, Q; Zuckerman, KS | 1 |
| Asara, JM; Clouse, SD; Gage, DA; Huber, SC; Oh, MH; Ray, WK | 1 |
| Al-Hendy, A; Feyles, V; Moshynska, O; Saxena, A | 1 |
| Coxon, PY; Klein, JB; McLeish, KR; Pierce, W; Ping, P; Powell, DW; Rane, MJ; Webster, R | 1 |
| Lee, D; Park, S; Shimizu, H; Shiro, Y; Shoun, H | 1 |
| Brandt, R; Eidenmüller, J; Fath, T; Hellwig, A; Reed, J; Sontag, E | 1 |
| Ballesteros, JA; Deupi, X; Haaksma, EE; Olivella, M; Pardo, L | 1 |
| England, K; Rumsby, MG | 1 |
| Armstrong, CG; Cohen, P; Fleming, Y; Goedert, M; Morrice, N; Paterson, A | 1 |
| Baringhaus, KH; Corsiero, D; Girbig, F; König, W; Kramer, W; Kurz, M; Lange, G; Sauber, K; Stengelin, S; Weyland, C | 1 |
| Almendral, JM; Maroto, B; Ramírez, JC | 1 |
| Garrison, N; O'Malley, BW; Rowan, BG; Weigel, NL | 1 |
| Boutry, M; Dambly, S | 1 |
| April, H; Ashby, B; Desai, S; Nwaneshiudu, C | 1 |
| Adachi, M; Imai, K; Itoh, F; Nakahata, A; Nakayama, I; Takekawa, M; Taya, Y; Tsukuda, H | 1 |
| Bartel, S; Karczewski, P; Krause, EG; Schlegel, WP; Vetter, D; Wallukat, G | 1 |
| Morley, SJ; Rulten, SL; Thorpe, JR | 1 |
| Karlsson, M; Parpal, S; Strålfors, P; Thorn, H | 1 |
| Exton, JH; Ho, WT; Xie, Z | 1 |
| Bebenek, A; Carver, GT; Drake, JW; Dressman, HK; Karam, JD; Konigsberg, WH; Ng , S; Petrov, V; Yang, G | 1 |
| Kolesnick, R; Xing, HR | 1 |
| Caillet, J; Dock-Bregeon, A; Ehresmann, C; Francklyn, CS; Moras, D; Rees, B; Romby, P; Sankaranarayanan, R; Springer, M | 1 |
| Kobayashi, K; Maruyama, H; Nishio, T; Ogawa, M; Saheki, T; Sunohara, N | 1 |
| Guévremont, D; Tate, WP; Wilson, DN | 1 |
| Kramer, DL; Pederson, TM; Rondinone, CM | 1 |
| Ivanov, KI; Mäkinen, K; Merits, A; Puustinen, P; Saarma, M | 1 |
| Thanka Christlet, TH; Veluraja, K | 1 |
| Lopaczynski, W; Nissley, P; Terry, C | 1 |
| Lai, MT; Vlahos, CJ; Zinda, MJ | 1 |
| Takahashi, E; Wells, TA; Wraight, CA | 1 |
| Ohkubo, T; Ozawa, M | 1 |
| Bennecib, M; Gong, CX; Grundke-Iqbal, I; Iqbal, K | 1 |
| Danilenko, VN; Elizarov, SM; Mironov, VA | 1 |
| Necela, B; Pollenz, RS | 1 |
| Avruch, J; Khokhlatchev, A; Kyriakis, JM; Luo, Z; Tzivion, G; Vavvas, D; Zhang, XF | 1 |
| Blethrow, JD; Burlingame, AL; Ganem, D; Huang, L; Lukac, DM; Morgan, DO; Polson, AG | 1 |
| Pietenpol, JA; Stewart, ZA; Tang, LJ | 1 |
| Ding, PZ; Wilson, TH | 1 |
| Cen, B; Ma, L; Pei, G; Xiong, Y | 1 |
| Alt, A; Herschkovitz, A; Kuroki, T; LeRoith, D; Liu, YF; Ohba, M; Paz, K; Sampson, SR; Tennenbaum, T; Zick, Y | 1 |
| Chong, C; Lim, L; Manser, E; Tan, L | 1 |
| Burd, AL; Chang, CY; El Kouhen, R; Erickson-Herbrandson, LJ; Law, PY; Loh, HH | 1 |
| Ashizawa, S; Hatakeyama, M; Higashi, H; Ishikawa, S; Koike, T; Kondo, T; Makita, Z; Nishizawa, H; Yamada, M | 1 |
| Cho, YK; Kim, JJ; Miziorko, HM; Ríos, SE | 1 |
| Cantley, LC; Lai, J; Leparc, GG; Obata, T; Volinia, S; Yaffe, MB | 1 |
| Aebersold, R; Watts, JD; Zhou, H | 1 |
| Borman, MA; Brautigan, DL; Eto, M; Haystead, TA; MacDonald, JA | 1 |
| Ito, Y; Kurono, S; Ogawa, T; Seifert, J | 1 |
| Anguissola, S; Comoglio, PM; Giordano, S; Gual, P; Parker, PJ | 1 |
| Chanas, B; Coulter, SJ; Ghanayem, B; Goldstein, JA; Johnson, EF; Tsao, CC; Wester, MR | 1 |
| Aimoto, S; Akaji, K; Kawakami, T | 1 |
| Benes, C; Soltoff, SP | 1 |
| Deng, X; May, WS; Ruvolo, PP | 1 |
| Akey, DL; Kim, PS; Malashkevich, VN | 1 |
| Horiuchi, H; Mutoh, E; Ohta, A; Takagi, M; Takaku, H | 1 |
| Butt, E; Gaestel, M; Immler , D; Kotlyarov, A; Laass, K; Meyer, HE | 1 |
| Accavitti, MA; Comer, FI; Hart, GW; Vosseller, K; Wells, L | 1 |
| Ito, M; Lu, T; Okamoto, M; Takemori, H; Tchoua, U; Tojo, H | 1 |
| Farrens, DL; Janz, JM | 1 |
| Jørgensen, JR; Pedersen, PA | 1 |
| Brownfield, L; Dashper, SG; Reynolds, EC; Rogers, AH; Slakeski, N; Zilm, PS | 1 |
| Comer, FI; Hart, GW | 1 |
| Meloni, MM; Taddei, M | 1 |
| Gergis, MR; Grogan, WM; Kodsi, EM; Langston, TB; Wallace, TJ | 1 |
| Haruta, T; Iwata, M; Kawahara, J; Kobayashi, M; Takano, A; Uno, T; Usui, I | 1 |
| Tsao, P; von Zastrow, M; Whistler, JL | 1 |
| Camonis, J; Demuth, D; Jaques, G; Krauss, S; Ligensa, T; Schumacher, R; Weidner, KM | 1 |
| Klonowski, W | 1 |
| Connors, N; DiMichele, L; Hughes, DL; Hughes, R; Petersen, LA; Salmon, P | 1 |
| Rusnak, F; Wengenack, NL | 1 |
| Kuriyama, H; Sohn, H | 1 |
| Engelman, DM; Senes, A; Ubarretxena-Belandia, I | 1 |
| Ammendola, S; Bonini, P; Cozzolino, F; De Chiara, G; Dello Sbarba, P; Garaci, E; Labardi, D; Lucibello, M; Marlier, LN; Nencioni, L; Palamara, AT; Rosini, P; Russo, T; Torcia, M; Zambrano, N | 1 |
| Fujisawa, K; Fukumoto, T; Fukunaga, R; Nagata, S; Watanabe-Fukunaga, R | 1 |
| Chalfant, CE; Galadari, S; Hannun, YA; Kroesen, BJ; Ogretmen, B; Pettus, BJ | 1 |
| Castranova, V; Ding, M; Huang, C; Leonard, SS; Li, J; Shi, X; Vallyathan, V; Wang, L | 1 |
| Eipper, BA; Keutmann, HT; Mains, RE; Steveson, TC; Zhao, GC | 1 |
| Einsiedel, J; Gmeiner, P; Hübner, H | 1 |
| Doumanis, J; Kumar, S; Quinn, L; Richardson, H | 1 |
| Fujibayashi, Y; Hori, M; Iijima, H; Isaka, S; Isogai, Y; Nakajima, K; Tagashira, M; Takamatsu, S; Teshima, T; Toma, K; Yamamoto, T; Yoshizawa-Kumagaye, K | 1 |
| Besley, BD; Casselman, R; Davey, S; Park, M; St Onge, RP | 1 |
| Blank, U; Deriano, L; Iannascoli, B; Le Mao, J; Martin-Verdeaux, S; Pombo, I; Rivera, J | 1 |
| Duus, JO; Gotfredsen, CH; Grøtli, M; Halkes, KM; Meldal, M; Miranda, LP | 1 |
| Halestrap, AP; Lockyer, PJ; Moule, SK; O'toole, A | 1 |
| Chen, Y; Ghosh, G; Huxford, T; Malek, S | 1 |
| Björefors, F; Borgh, A; Ekeroth, J; Konradsson, P; Liedberg, B; Lundström, I | 1 |
| Bigas, A; Caelles, C; Espinosa, L; Inglés-Esteve, J; Milner, LA | 1 |
| Paller, AS; Sun, P; Wang, XQ | 1 |
| Lin, YH; Yang-Yen, HF | 1 |
| Albar, JP; Bonay, P; Camafeita, E; Fernández-Fernández, MR; García, JA; Méndez, E | 1 |
| Guan, JL; Han, DC; Shen, TL | 1 |
| Feshchenko, EA; Swaminathan, G; Teckchandani, AM; Tsygankov, AY | 1 |
| Parsons, JT; Weed, SA | 1 |
| Brown, NR; Endicott, JA; Hernandez, H; Johnson, LN; Lawrie, AM; Noble, ME; Robinson, CV; Tito, P | 1 |
| Kaasik, A; Minajeva, A; Ohisalo, J; Paju, K | 1 |
| Aebersold, R; Burley, SK; Gingras, AC; Gygi, SP; Miron, M; Niedzwiecka, A; Polakiewicz, RD; Raught, B; Sonenberg, N; Wyslouch-Cieszynska, A | 1 |
| Kabashima, T; Kawaguchi, T; Takenoshita, M; Uyeda, K | 1 |
| Saleh, SM; Takemoto, DJ; Takemoto, LJ; Zoukhri, D | 1 |
| Andreeva, AV; Kutuzov, MA | 1 |
| Iniguez-Lluhi, JA; Jefferson, LS; Kimball, SR; Romanelli, A; Shah, OJ | 1 |
| Earnest, TN; Hol, WG; Kim, S; Kim, Y | 1 |
| Bean, LJ; Stark, GR | 1 |
| Hébert, TE; Logothetis, DE; Mirshahi, T; Robillard, L; Zhang, H | 1 |
| Bordeau, V; Felden, B; Hanawa-Suetsugu, K; Himeno, H; Muto, A | 1 |
| Avila-Flores, A; Betanzos, A; González-Mariscal, L; Islas, S; Moreno, J; Rendón-Huerta, E; Robles-Flores, M | 1 |
| Takahashi, K | 1 |
| Liou, YC; Lu, KP; Lu, PJ; Noel, JP; Zhou, XZ | 1 |
| Miziorko, HM; Ríos, SE; Runquist, JA; Vinarov, DA | 1 |
| Brennan, JA; Chaika, OV; Lewis, RE; Volle, DJ | 1 |
| Adachi, S; Ebara, S; Inui, H; Matsumura, T; Miyatake, K; Nakano, Y; Takenaka, S; Toyoshima, S; Watanabe, F; Yamaji, R | 1 |
| Fisher, RJ; Graham, C; Li, A; Liu, Y; Shaw, S | 1 |
| Kräusslich, HG; Müller, B; Patschinsky, T | 1 |
| Gerken, TA; Gilmore, M; Zhang, J | 1 |
| Badorff, C; Dimmeler, S; Holzmann, Y; Rössig, L; Zeiher, AM | 1 |
| Hemi, R; Kanety, H; Karasik, A; Paz, K; Wertheim, N; Zick, Y | 1 |
| Cantley, LG; Liu, ZX; Nickel, C; Thomas, S; Yu, CF | 1 |
| Crosby, D; Poole, AW | 1 |
| Jin, P; Levitan, IB; Weiger, TM; Wu, Y | 1 |
| Gooley, AA; Slade, MB; Williams, KL; Winter, G | 1 |
| Flavell, RR; Goger, M; Huse, M; Kuriyan, J; Muir, TW; Trester-Zedlitz, M | 1 |
| Goto, J; Iida, H; Ikeda, M; Inoue, S; Maruoka, T; Mori, Y; Nagasoe, Y | 1 |
| Chang, NS | 1 |
| Herbert, TP; Proud, CG; Tee, AR | 1 |
| Ernst, JF; Prill, SK | 1 |
| Cox, TC; Hopwood, B; Short, KM; Yi, Z | 1 |
| Liang, J; Luba, J; McGee, MP | 1 |
| Aschenbach, WG; Goodyear, LJ; Hirshman, MF; Sakamoto, K | 1 |
| Ferrero, P; Mattiazzi, A; Mundiña-Weilenmann, C; Said, M; Vittone, L | 1 |
| Cai, S; Exton, JH; Ho, WT; Spellman, R; Xie, Z | 1 |
| Dunn, MF; Jhee, KH; McPhie, P; Miles, EW; Niks, D | 1 |
| Sheibani, N; Sorenson, CM | 1 |
| Clevers, H; Destree, O; Meeldijk, J; van der Zee, R; van Noort, M | 1 |
| Nagao, Y | 1 |
| Aitken, A; Cronshaw, A; Dubois, T; Kerai, P; Learmonth, M | 1 |
| Hagemann, D; Xiao, RP | 1 |
| Baudouin, E; Charpenteau, M; Ranjeva, R; Ranty, B | 1 |
| Dawson, JP; Engelman, DM; Weinger, JS | 1 |
| Bae, CD; Jeon, S; Kim, S; Kim, YS; Park, J; Park, JB; Suh, PG | 1 |
| James, MN; Lall, MS; Ramtohul, YK; Vederas, JC | 1 |
| Chen, H; Dong, LQ; He, H; Liu, F; Quon, MJ; Wick, KR; Wick, MJ | 1 |
| Sadler, JE; Zheng, X | 1 |
| Cohen, SB; Halcomb, RL | 1 |
| Gerashchenko, BI; Hino, M; Hosoya, H; Ueda, K | 1 |
| Flamand, L; Gosselin, J; Gravel, A | 1 |
| Brennan, P; Cantrell, D; Dennis, PB; Pullen, N; Saitoh, M; Thomas, G | 1 |
| Cornelius, F; Mahmmoud, YA | 1 |
| Fenel, F; Leisola, M; Turunen, O; Vuorio, M | 1 |
| Brown, MC; Terfera, DR; Turner, CE | 1 |
| Bakó, E; Bíró, T; Czifra, G; Felszeghy, S; Gergely, P; Módis, L; Szucs, K; Zákány, R | 1 |
| Ishimoto, A; Kadowaki, T; Lee, JS; Matsubayashi, H; Matsuda, Y; Sese, S; Yanagawa, S | 1 |
| Liu, GZ; Pi, LY; Ronald, PC; Song, WY; Walker, JC | 1 |
| Bell, A; Bowen, WC; Mars, WM; Michalopoulos, GK; Monga, SP; Mulé, K; Pediaditakis, P; Wang, X; Zarnegar, R | 1 |
| Hall, DD; Hell, JW; Lim, IA | 1 |
| Figueiredo, DL; Martins, JR; Masuda, CA; Montero-Lomeli, M; Morais, BL; Neto, DC | 1 |
| Adachi, M; Lewis, EJ | 1 |
| Coles, LC; Shaw, PE | 1 |
| Derksen, J; Ebbelaar, M; Mariani, C; Quentin, M; van Der Valk, H | 1 |
| Limeschenko, E; Mokrousov, I; Narvskaya, O; Otten, T; Steklova, L; Vyshnevskiy, B | 1 |
| Cenni, V; Döppler, H; Maraldi, N; Newton, AC; Sonnenburg, ED; Toker, A | 1 |
| Penzo, D; Pinna, LA; Ruzzene, M | 1 |
| Dittmann, KH; Mayer, C; Rodemann, HP | 1 |
| Huang, YT; Hwang, JJ; Ke, FC; Lee, LT; Lee, MT; Lee, PP; Liebow, C; Lo, TB; Schally, AV | 1 |
| Bossemeyer, D; Breitenlechner, CB; Engh, RA; Holak, TA; Huber, R; Seifert, MH | 1 |
| Asara, JM; Garner, CC; Kane, S; Lane, WS; Lienhard, GE; Liu, SC; Sano, H | 1 |
| Bordone, L; Campbell, C | 1 |
| Kelm, O; Lehmann, WD; Nigg, EA; Wind, M | 1 |
| Allibardi, S; Bendinelli, P; Luzi, L; Maroni, P; Piccoletti, R; Samaja, M; Terruzzi, I; Vesco, F | 1 |
| Cheng, NH; Hirschi, KD; Pittman, JK; Shigaki, T | 1 |
| Bruins, AP; Janssen, DB; Jekel, PA; Jeronimus-Stratingh, CM; Polderman-Tijmes, JJ; Sonke, T; Van Der Laan, JM | 1 |
| Facchini, A; Flamigni, F; Ghelli, A; Hrelia, S; Porcelli, AM; Rugolo, M | 1 |
| Deng, JT; Erdodi, F; Hartshorne, DJ; Haystead, TA; Kiss, E; MacDonald, JA; Murányi, A; Walsh, MP; Wilson, DP; Wu, Y | 1 |
| Aisen, P; Ikuta, K; Zak, O | 1 |
| Amour, A; Becherer, JD; Dodds, P; Knäuper, V; Lee, MH; Maskos, K; Murphy, G; Verma, V | 1 |
| Bertozzi, CR; Grogan, MJ; Marcaurelle, LA; Pratt, MR | 1 |
| Cascante, M; Chassagnole, C; de Atauri, P; Fell, DA; Magret, D; Mazat, JP | 1 |
| el-Shemerly, M; Faisal, A; Hess, D; Nagamine, Y | 1 |
| Huang, S; Jonsson, BH; Sauer-Eriksson, AE; Sjöblom, B | 1 |
| Ewton, DZ; Friedman, E; Jin, K; Kim, GY; Mercer, SE; Yan, Z | 1 |
| Chen, CW; Chen, DS; Chen, PJ; Lee, CH; Tsay, YG; Wu, HL | 1 |
| Horwitz, SB; Yang, CP | 1 |
| Annila, A; Pollesello, P | 1 |
| Chen, HY; Zhou, GJ | 1 |
| Dracheva, S; Fang, YY; Koh, PO; Lidow, MS; Sealfon, SC; Song, ZM; Undie, AS; Zhang, L | 1 |
| Bae, SS; Choi, JH; Oh, YS; Ryu, SH; Suh, PG; Yun, SU | 1 |
| Chang, WT; Chow, YW; Hsu, CY; Huang, PC; Li, AH; Wang, HL | 1 |
| Baltus, GA; Bear, JE; Gertler, FB; Kwiatkowski, AV; Loureiro, JJ; Rubinson, DA | 1 |
| Browning, GF; Crabb, BS; Jackson, DC; Peters, MA | 1 |
| Bangash, S; Lopatka, K; Paller, AS; Sun, P; Wang, XQ | 1 |
| Chen, W; Cong, M; Exum, ST; Lefkowitz, RJ; Lin, FT; Shenoy, S | 1 |
| McKeown-Longo, PJ; Zheng, M | 2 |
| Erikson, RL; Jang, YJ; Ma, S; Terada, Y | 1 |
| Greengard, P; Liu, F; Nairn, AC; Virshup, DM | 1 |
| Hata, J; Hatai, T; Ichijo, H; Inoshita, S; Sano, M; Takeda, K; Terada, Y; Umezawa, A | 1 |
| Han, SW; Henrique-Silva, F; Machado-Santelli, GM; Pfister, SC | 1 |
| Bokoch, GM; Cha, CI; Kim, EG; Kim, SR; Kim, YG; Lee, CS; Park, D; Quan, SH; Shin, EY; Shin, KS; Soung, NK; Woo, KN | 1 |
| Hashiguchi, M; Hashiguchi, T; Hisanaga, S; Saito, T | 1 |
| De Jonge, BL; Gage, D; Xu, N | 1 |
| de Graaf, A; Revuelta, JL; Santos, MA; Schlüpen, C; Stahmann, KP; Weber, U | 1 |
| Mattiazzi, A; Mundiña-Weilenmann, C; Said, M; Vittone, L | 2 |
| Chen, EY; Clarke, DM | 1 |
| Schwalbe, RA; Wingo, CS; Xia, SL | 1 |
| Abraham, RT; Choi, KM; Lawrence, JC; Lin, TA; McMahon, LP | 1 |
| Beffert, U; Bock, HH; Brady, ST; Herz, J; Morfini, G; Reyna, H | 1 |
| Boo, YC; Hwang, J; Jo, H; Kemp, BE; Lum, H; Michell, BJ; Sykes, M | 1 |
| Castranova, V; Costa, M; Huang, C; Jiang, BH; Ke, Q; Leonard, SS; Li, J; Shi, X; Zhong, XS | 1 |
| Hori, H; Kawahara, J; Kobayashi, M | 1 |
| Biswas, SC; Greene, LA | 1 |
| Gruic-Sovulj, I; Landeka, I; Söll, D; Weygand-Durasevic, I | 1 |
| Galili, G; Tang, G; Zhu, X | 1 |
| Kageyama, Y; Ochi, H; Ogino, H; Yasuda, K | 1 |
| Elhammer, A; Gerken, TA; Levine, J; Zhang, J | 1 |
| Amburgey, J; Potter, R; Shafii, S; Slawson, C | 1 |
| Burton, NP; Dalton, H; Murrell, JC; Slade, SE; Smith, TJ | 1 |
| Dimmock, JR; Hollenberg, MD; Pasha, MK; Sharma, RK | 1 |
| Hori, M; Kitagawa, K; Kuwabara, K; Mabuchi, T; Matsumoto, M; Omura-Matsuoka, E; Sasaki, T; Sugiura, S; Takasawa, K; Tanaka, S | 1 |
| Fredriksson, R; Höglund, PJ; Lagerström, MC; Schiöth, HB | 1 |
| Kölling, R | 1 |
| Cole, RN; Cronshaw, JM; Hart, GW; Matunis, MJ; Vosseller, K; Wells, L | 1 |
| Cabaniols, JP; Hepp, R; Roche, PA | 1 |
| Arac, D; Dunn, MF; Kulik, V; Niks, D; Schlichting, I; Seidel, R; Weyand, M | 1 |
| Gonzalez, FJ; Guo, H; Inoue, Y; Kuo, PC; Wei, J | 1 |
| Baffi, MO; Lin, CH; Ma, G; Orr, M; Wathelet, MG; Yang, H | 1 |
| Gautschi, I; Hannila-Handelberg, T; Hiltunen, TP; Kantola, I; Kontula, K; Petäjäniemi, N; Schild, L; Tikkanen, I; Virtamo, J | 1 |
| Björquist, A; Hallén, S; Ostlund-Lindqvist, AM; Sachs, G | 1 |
| Chu, G; Kranias, EG | 1 |
| Birnbaumer, M; Innamorati, G; Le Gouill, C | 1 |
| Kasahara, M; Morohashi, K; Suzuki, T; Umesono, K; Yoshioka, H | 1 |
| Bichsel, SJ; Hemmings, BA; Rogniaux, H; Stegert, MR; Tamaskovic, R | 1 |
| Greif, DM; Kou, R; Michel, T | 1 |
| Agerholm-Larsen, B; Chen, W; Linsel-Nitschke, P; Martinez, LO; Silver, DL; Tall, AR; Wang, N | 1 |
| Boxer, SG; Rosell, FI | 1 |
| Brew, K; Chen, Y; Chung, L; Nagase, H; Wei, S | 1 |
| Duguay, D; Grandvaux, N; Hiscott, J; Lin, R; Servant, MJ; tenOever, BR | 1 |
| Hepler, JR; Hollinger, S; Ramineni, S | 1 |
| Bast, RC; Hittelman, WN; Le, XF; Li, C; Liu, J; McWatters, A; Mills, GB | 1 |
| Ishitani, T; Matsumoto, K; Ninomiya-Tsuji, J | 1 |
| Csizmadia, IG; Csonka, GI; Perczel, A; Schubert, GA; Sosa, CP | 1 |
| Fredriksson, R; Gloriam, DE; Höglund, PJ; Lagerström, MC; Schiöth, HB | 1 |
| Ridyard, MS; Robbins, SM | 1 |
| Daldal, F; Darrouzet, E | 1 |
| Ghosh, S; Hunter, T; Shah, OJ | 1 |
| Bryckaert, M; Contreres, JO; Dupuy, E; Habib, A; Herbert, JM; Job, B; Levy-Toledano, S; Rosa, JP; Savi, P; Simoneau, G | 1 |
| Litscher, ES; Wassarman, PM; Williams, Z | 1 |
| Armstrong, DL; Birnbaumer, L; Darden, T; Erxleben, C; Gomez-Alegria, C; Mori, Y | 1 |
| Aitken, A; Cronshaw, A; Dubois, T; Howell, S; Learmonth, M; Zemlickova, E | 1 |
| Friesel, R; Harkins, LK; Kovalenko, D; Nadeau, RJ; Yang, X | 1 |
| Haga, K; Haga, T; Yoshida, N | 1 |
| García, C; González, FA; Hojas, R; José, C; Nogales, A; Ropero, P; Valverde, F; Villar, L; Villegas, A | 1 |
| Ceryak, S; Ha, L; Patierno, SR | 1 |
| Fang, H; Flier, JS; Masuzaki, H; Shinyama, H | 1 |
| Funahashi, HO; Kikuchi, A; Nakagawa, Y; Nakao, A; Sawada, M; Suda, N; Suzuki, M; Takami, Y; Yoshida, S | 1 |
| Ames, RS; Bock, D; Hamacher, H; Jenkinson, L; Klos, A; Köhl, J; Rheinheimer, C; Schaefer, M; Settmacher, B; Wise, A | 1 |
| Catt, KJ; Clark, AJ; Gáborik, Z; Hunyady, L; Mihalik, B; Várnai, P | 1 |
| Apasov, SG; Caldwell, CC; Chen, P; Lukashev, DE; Margulies, DH; Sitkovsky, MV | 1 |
| Hresko, RC; Mueckler, M; Murata, H | 2 |
| Brautigan, DL; Leach, C; Shenolikar, S | 1 |
| Lienhard, GE; Mîinea, CP | 1 |
| Carvalho, I; Field, RA; Ravindranathan Kartha, KP; Scheuerl, SL | 1 |
| Kupferwasser, D; Lam, J; Lee-Fruman, KK; Phin, S | 1 |
| Inoue, J; Ohsugi, M; Shiroguchi, K; Tokai-Nishizumi, N; Toyoshima, YY; Yamamoto, T | 1 |
| Elce, JS; Huynh, KK; Jia, Z; Smith, SD; Wells, A | 1 |
| Choudhury, P; Datta, B; Datta, R; Ghosh, A | 1 |
| Nakajima, H; Nishida, E; Taniguchi, E; Toyoshima-Morimoto, F | 1 |
| Dihazi, H; Eschrich, K; Kessler, R | 1 |
| Duonor-Cérutti, M; Galibert, L; Ravallec, M; Rocher, J; Volkoff, AN; Webb, BA | 1 |
| Cole, GJ; Halfter, W; Winzen, U | 1 |
| Boyle, P; English, DR; Giles, GG; Hopper, JL; McCredie, MR; Morris, H; Neufing, P; Severi, G; Southey, MC; Tesoriero, A; Tilley, W | 1 |
| Borck, G; Martiné, U; Pohlenz, J; Roth, C; Wildhardt, G | 1 |
| Banger, N; Berdel, WE; Chou, TC; Kiehl, M; Koch, OM; Müller-Tidow, C; Probst, M; Serve, H; Sindermann, JR; Zühlsdorf, M | 1 |
| Bessant, DA; Bhattacharya, SS; Bird, AC; Fitzke, FW; Holder, GE; Payne, AM | 1 |
| D'Aquila, TG; Gaynor, RB; Lizardi, I; Provost, E; Rimm, DL; Stern, J; Yamamoto, Y | 1 |
| Lovly, CM; Piwnica-Worms, H; Schwarz, JK | 1 |
| Eiberg, H; Ernst, E; Lindenberg, S; Olesen, C; Petersen, K; Silber, J; Tommerup, N | 1 |
| Clark, S; Leever, JD; Partin, KM; Weeks, AM | 1 |
| Balcells, S; Baldellou, A; Campistol, J; Couce, ML; Grinberg, D; Muñoz, C; Pintó, X; Rodés, M; Urreizti, R; Vilarinho, L; Vilaseca, MA | 1 |
| Baker, DA; Deng, W; Meyer, DJ; Parbhu-Patel, A | 1 |
| Toker, A | 1 |
| Cladière, L; Jensen, ON; Kjellström, S; Madec, E; Obuchowski, M; Séror, SJ; Stensballe, A | 1 |
| Bohmann, D; Schneider, S; Seto, E; Wagner, EF; Weiss, C; Zhang, X | 1 |
| Kasuga, M; Mori, T; Nishizawa, A; Noda, T; Ogawa, W; Sakaue, H; Takashima, Y; Teshigawara, K | 1 |
| Chen, RH; Chung, E | 1 |
| Burbach, JP; Hoekman, MF; Jacobs, FM; Smidt, MP; van der Heide, LP; Wijchers, PJ | 1 |
| Griendling, KK; Rocic, P; Seshiah, P | 1 |
| Furuhata, T; Hirata, K; Ichimiya, S; Kawakami, M; Kihara, C; Kimura, Y; Mukaiya, M; Okita, K; Satoh, M; Yanai, Y; Zenbutsu, H | 1 |
| Boza, J; Breuillé, D; Faure, M; Mercier, S; Mettraux, C; Moënnoz, D; Montigon, F; Obled, C; Schiffrin, EJ | 1 |
| Bertozzi, CR; Hang, HC; Hanover, JA; Kim, EJ; Vocadlo, DJ | 1 |
| Bérard, MP; Chaïb, S; Cynober, L; De Bandt, JP; Neveux, N; Osowska, S | 1 |
| Cohen, P; Davis, RJ; McLaren, A; Morton, S | 1 |
| Jones, DN; Kruse, SW; Smith, DP; Zhao, R | 1 |
| Aboul-Enein, HY; El-Awady, MI; Heard, CM | 1 |
| Mariner, DJ; Reynolds, AB; Xia, X | 1 |
| Chen, H; Dong, LQ; Liu, F; Quon, MJ; Ramos, FJ; Wick, MJ | 1 |
| Cozzone, AJ; Doublet, P; Girard-Blanc, C; Kremer, L; Molle, V; Prost, JF | 1 |
| Hindson, VJ | 1 |
| Araiso, T; Demura, M; Kamo, N; Kikukawa, T; Nitta, K; Okita, H; Sato, M; Shimono, K | 1 |
| Calvete, JJ; Celda, B; Kovacs, H; Marcinkiewicz, C; Monleon, D; Moreno-Murciano, MP | 1 |
| Guan, H; Hou, S; Ricciardi, RP | 1 |
| Compton-Toth, BA; Gray, JA; Roth, BL | 1 |
| Ozawa, M | 1 |
| Chen, Z; Ullrich, A; Wu, Y | 1 |
| HAZAN, SJ; LITTLEJOHN, JM; SINGAL, SA; SYDENSTRICKER, VP | 1 |
| DELLUVA, AM | 1 |
| CHUNG, D; LEVY, AL | 1 |
| ELSDEN, SR; LEWIS, D | 1 |
| LONGENECKER, JB; SNELL, EE | 1 |
| MORGAN, JF; MORTON, HJ | 1 |
| HAFF, RF; SWIM, HE | 1 |
| DODGSON, KS; LLOYD, AG; TUDBALL, N | 1 |
| BRICTEUX-GREGOIRE, S; DEWANDRE, A; FLORKIN, M | 1 |
| DEWEY, VC; KIDDER, GW | 1 |
| FLAVIN, M; SLAUGHTER, C | 1 |
| GIBSON, KD; NEUBERGER, A; TAIT, GH | 1 |
| BEHRMAN, EJ; GOLDSTEIN, L; KNOX, WE | 1 |
| UNEMOTO, T | 1 |
| LEVINE, EM; SIMMONDS, S | 1 |
| GOODER, H; MICHEL, MF | 1 |
| ARIMORI, S; IWASAKI, I; KAWANISHI, Y | 1 |
| ROTHSTEIN, M; TOMLINSON, G | 1 |
| SIEPMANN, E; ZAHN, H | 1 |
| BOTTOMLEY, RH; MORRIS, HP; PITOT, HC | 1 |
| BOLLE, A; KELLENBERGER, E; LARK, KG | 1 |
| ADELBERG, EA; PITTARD, J | 1 |
| CHAMPIGNY, ML | 1 |
| TANG, J | 1 |
| IKEKAWA, N | 1 |
| WALLER, JP | 1 |
| NEALE, S; TRISTRAM, H | 1 |
| O'BARR, TP | 1 |
| RUMLEY, MK; UZMAN, LL; VANDENNOORT, S | 1 |
| SCHEPARTZ, B | 1 |
| BIRD, R | 1 |
| BRAUN, L | 1 |
| GENTY, N; MELONI, GA; VENDRELY, R | 1 |
| DATTA, P; GEST, H; SEGAL, HL | 1 |
| BAILY, P; HARINGTON, JS; KILROE-SMITH, TA | 1 |
| COLACICCO, G | 1 |
| Anderson, JO; Dobson, DC; Warnick, RE | 1 |
| Salmon, WD | 1 |
| DYKE, KG | 1 |
| NICHOLAS, DJ; RAO, PS | 1 |
| LORINCZ, AB; RYAN, WL | 1 |
| HARRINGTON, H; SAKAMI, W | 1 |
| WALIGORA, Z; WENDER, M | 1 |
| GRUNBERG-MANAGO, M; MICHELSON, AM | 1 |
| CHRISTENSEN, HN; WINTER, CG | 1 |
| FOX, SW; YUYAMA, S | 1 |
| DELALLOSA, P; JUTISZ, M; TERTRIN, C | 1 |
| WOOL, IG | 1 |
| ULRICH, F | 1 |
| CREMER, JE | 1 |
| FASELLA, P; GIARTOSIO, A; TURANO, C; VECCHINI, P | 1 |
| Dean, RF; Whitehead, RG | 1 |
| CRAWFORD, IP; ITO, J | 1 |
| VOLKOV, VP | 1 |
| CRAFT, MK; DEWALD, HA; NICOLAIDES, ED | 1 |
| LYNCH, JL; NEUHAUS, FC | 1 |
| COHEN, GN; PATTE, JC | 1 |
| GATGOUNIS, J; HESTER, W | 1 |
| KNAUFF, HG; MILLER, B; SEYBOLD, D | 1 |
| PORCELLATI, G | 2 |
| KING, NK; LOONEY, FD; WINFIELD, ME | 1 |
| PIZER, LI; POTOCHNY, ML | 1 |
| BUCHANAN, BB; RABINOWITZ, JC | 1 |
| PENTZ, EI | 1 |
| DEMEREC, M | 1 |
| BENGTSSON, S; DINTER, Z | 1 |
| NOVOGRODSKY, A; SCANNONE, H; WELLNER, D | 1 |
| ANDERSON, B; HOFFMAN, P; MEYER, K; RILEY, J; SAMPSON, P; SENO, N | 1 |
| AVERY, EH; FREEDLAND, RA | 1 |
| MCDOWALL, MA; SMITH, EL | 1 |
| HILL, J; LEACH, SJ | 1 |
| ANDERSON, B; HOFFMAN, P; MEYER, K; SENO, N | 1 |
| BLAU, K; DARBRE, A | 2 |
| DONDON, J; GRUNBERG-MANAGO, M | 1 |
| NARITA, K; OGATA, K; SATO, N | 1 |
| CIAMMARUGHI, A; FLORIDI, A; PORCELLATI, G | 1 |
| JOHNSON, AH; STOKES, JL | 1 |
| BASSETT, EW; BEISER, SM; KABAT, EA; PRYZWANSKY, K; TANENBAUM, SW | 1 |
| ISHIKAWA, E; NINAGAWA, T; SUDA, M | 1 |
| Lede, MN; Rio, ME; Sanahuja, JC | 1 |
| BHAVANANDAN, P; CARUBELLI, R; GOTTSCHALK, A | 1 |
| CLAMP, JR; HOUGH, L | 1 |
| GREENBERG, DM; NAGABHUSHANAM, A | 1 |
| BOSCH, L; GOUT, PW; HOOGENDAM, BW; VOORMA, HO | 1 |
| GOTTSCHALK, A | 1 |
| CESIANO, C; DE LEO, C; DELLA PIETRA, G; QUAGLIARIELLO, E | 1 |
| Badwey, JA; Ge, Q; Ohira, T; Van Dyke, T; Zhan, Q | 1 |
| Ingr, M; Konvalinka, J; Majerová, E; Strísovský, K; Uhlíková, T | 1 |
| Mohapatra, DP; Nau, C | 1 |
| Ferguson, G; Lawrence, JC; Mothe-Satney, I | 1 |
| Rao, MR; Ullas, KS | 1 |
| Katada, T; Kontani, K; Kurosu, H; Momose, H; Nishina, H; Tsujimoto, N; Tsujita, K | 1 |
| Bölck, B; Brixius, K; Mehlhorn, U; Schwinger, RH; Wollmer, A | 1 |
| Busse, R; Fichtlscherer, B; Fleming, I; Kohlstedt, K; Lenasi, H; Mülsch, A | 1 |
| Arcand, M; Iouk, T; Jansen, G; Meloche, S; Thomas, DY; Whiteway, M; Wu, C; Zhong, M | 1 |
| Fauser, BC; Gromoll, J; Laven, JS; Mulders, AG; Nieschlag, E; Simoni, M; Suryandari, DA | 1 |
| Chen, MS; Piwnica-Worms, H; Ryan, CE | 1 |
| Ito, F; Takeuchi, K | 1 |
| Schmitz-Peiffer, C; Whitehead, JP | 1 |
| Fu, GK; Jin, P; Rowe-Teeter, C; Stuve, LL; Yang, J; Zhang, J | 1 |
| Ansari, A; Dorovkov, MV; Ryazanov, AG; Ryazanova, LV | 1 |
| Beisenherz-Huss, C; Cole, R; Gewinner, C; Groner, B; Hart, G; Zachara, N | 1 |
| Helman, LJ; Wan, X | 1 |
| Hemmi, H; Inohara-Ochiai, M; Min, KS; Nakayama, T; Nishino, T; Noguchi, A; Ohshima, Y; Okada, M; Yano, M | 1 |
| Backlund, PS; Boykins, RA; Chen, HC; Li, W; Wang, G | 1 |
| Adler, D; Fick, G; Hughes, RM; Kanji, N; Trpkov, K | 1 |
| Ashraf, QM; Delivoria-Papadopoulos, M; Fritz, KI; Mishra, OP; Zubrow, AB | 1 |
| Berenstein, A; Ho, M; Jayaraman, T; Kohyama, S; Li, X; Malathi, K; Silane, M; Soghoian, D | 1 |
| Furutani, Y; Kamo, N; Kandori, H; Shimono, K; Sudo, Y | 1 |
| Lei, H; Smith, PE | 1 |
| Maeno, T; Morimoto, Y; Natsume, H; Ogihara, M; Ohtake, K; Ueda, H | 1 |
| Buscemi, N; Li, MX; Lindhout, DA; Sykes, BD; Van Eyk, JE; Wang, X | 1 |
| Adam, SA; Gan, L; Kan, D; Majeski, M; Pan, H; Unterman, TG; Zhao, X | 1 |
| Ichinose, T; Yamauchi, T; Yoshimura, Y | 1 |
| Morita, M; Okuno, M; Takemura, A | 1 |
| Baron, S; Beaudoin, C; Communal, Y; Leotoing, L; Manin, M; Morel, L; Veyssiere, G | 1 |
| Feng, XL; Han, WN; Li, H; Liu, WD; Wang, L; Yang, XY; Yao, KT; Zhou, W | 1 |
| Anderson, DE; Dyda, F; Ghirlando, R; Hickman, AB; Obsil, T | 1 |
| Besra, GS; Cozzone, AJ; Girard-Blanc, C; Kremer, L; Molle, V; Prost, JF | 1 |
| Kahn, RA; McKay, MM | 1 |
| Ballesteros, JA; Campillo, M; Deupi, X; Govaerts, C; Olivella, M; Pardo, L | 1 |
| Laprise, P; Rivard, N; Viel, A | 1 |
| Häussinger, D; Reinehr, R | 1 |
| Briggs, JM; Lee, KW; Martinis, SA; Mursinna, RS | 1 |
| Hermosilla, R; Neuschäfer-Rube, F; Püschel, GP; Rehwald, M; Rönnstrand, L; Schülein, R; Wernstedt, C | 1 |
| Bijur, GN; Jope, RS | 1 |
| Arranz Mascarós, P; Gallagher, JF; Glidewell, C; Godino Salido, ML; Gutiérrez Valero, MD; López Garzón, R; Low, JN | 1 |
| Ball, H; Bogyo, M; Bradshaw, RA; Burlingame, AL; Chalkley, RJ; Darula, Z; Fainzilber, M; Greenbaum, D; Medzihradszky, KF; Perlson, E; Tyson, DR | 1 |
| Averin, O; Chatterjee, C; Kelleher, NL; Miller, LM; van der Donk, WA; Xie, L | 1 |
| Fujieda, K; Horibe, T; Kataoka, M; Kikuchi, M; Kimura, T; Kojima, T; Tanaka, T | 1 |
| FLING, M; HOROWITZ, NH | 1 |
| BONJOUR, G; DESNUELLE, P | 1 |
| Johnson, MS; Moretti, L; Pentikäinen, OT; Settimo, L | 1 |
| Aitken, SM; Kirsch, JF | 1 |
| Deinzer, ML; Kim, MY; Mixon, AE; Spencer, PS; Stapels, MD; Trimpin, S | 1 |
| Bahassi, el M; Hennigan, RF; Myer, DL; Stambrook, PJ | 1 |
| Jho, EH; Kim, DJ; Kim, SI; Lee, MS; Park, CS; Song, WK; Youn, CY | 1 |
| Crawford, E; Hendzel, MJ; Lever, MA; Th'ng, JP | 1 |
| Blumberg, PM; Edenson, S; Gavva, NR; Klionsky, L; Lile, J; Louis, JC; Pearce, LV; Porreca, F; Qu, Y; Shi, L; Sun, Y; Tamir, R; Toth, A; Treanor, JJ; Vanderah, TW; Viswanadhan, VN; Wild, K; Zhang, TJ | 1 |
| Gupta, D; Khandelwal, RL | 1 |
| Chen, JS; Exton, JH | 1 |
| Babior, BM; Bouin, AP; Dagher, MC; Fuchs, A; Gutierrez, A; Lopes, LR; Young, B | 1 |
| Dabiri, D; Esfandiarei, M; Luo, H; McManus, BM; Suarez, A; Yanagawa, B; Zhang, J | 1 |
| Arnold, H; Chasse, D; Counter, CM; Cunningham, M; Hahn, WC; Ivaldi, G; Means, AR; Monteith, T; Nevins, JR; Sears, R; Shenolikar, S; Stukenberg, PT; Uchida, T; Yeh, E | 1 |
| Luo, JH; Michalopoulos, GK; Micsenyi, A; Monga, SP; Sneddon, T; Tan, X | 1 |
| Gerken, TA | 1 |
| Kikkawa, U; Matsuzaki, H; Yamamoto, T | 1 |
| Donini, M; Dusi, S; Margotto, D; Mazzi, P; Wientjes, F | 1 |
| Cheng, AL; Chuang, SE; Song, YC; Yeh, KH; Yeh, PY | 1 |
| Kemp, GD; Llinas, AJ; Ryan, JT; Smillie, DA; Sommerville, J | 1 |
| Huffman, HA; Phail, ME; Rosenow, MA; Wachter, RM | 1 |
| Hatakeyama, S; Imaki, H; Ishida, N; Kamura, T; Nakayama, K; Nakayama, KI; Nishiyama, M; Okumura, F; Tsunematsu, R; Yada, M | 1 |
| Lazo, PA; Santos, CR; Sevilla, A; Vega, FM | 1 |
| Ekino, K; Furukawa, K; Goto, M; Oka, T; Sameshima, Y; Shinoda, N | 1 |
| Chang, NS; Heath, J; Hsu, LJ; Jambal, P; Pugazhenthi, S; Schultz, L; Su, M; Sze, CI | 1 |
| Dubinett, SM; Huang, M; Keane, MP; Rozengurt, E; Sharma, S; Strieter, RM; Zhang, L; Zhu, LX | 1 |
| Hardin, SC; Huber, SC | 1 |
| Liu, ZR; Yang, L | 1 |
| Banga, SS; Harvey, BP; Ozer, HL | 1 |
| Adams, JA; Aubol, BE; Ghosh, G; Lukasiewicz, R; Ungs, L | 1 |
| Isojima, Y; Nagai, K; Takano, A | 1 |
| Kennelly, PJ; King, DM; Wurgler-Murphy, SM | 1 |
| Fujishiro, M; Goshima, Y; Ishii, T; Kitamura, H; Masuda, M; Matsuse, T; Teramoto, S | 1 |
| Gul, YA; Ithnin, H; Khor, TO; Seow, HF | 1 |
| Alonso, Adel C; Grundke-Iqbal, I; Iqbal, K; Mederlyova, A; Novak, M | 1 |
| Bahr, I; Dernedde, J; Kilian, K; Mueller, EC; Tauber, R | 1 |
| Borman, MA; Erdodi, F; Hartshorne, DJ; Haystead, TA; Ma, C; MacDonald, JA; Wooldridge, AA | 1 |
| Dowling, M; Kao, GD; Liu, F; Yang, XJ | 1 |
| Bijur, GN; Li, X; Styles, NA; Zhu, W | 1 |
| Jackson, CM; Shi, F; Winzor, DJ | 1 |
| Cooper, JA; Korneeva, NL; Ling, J; Merrick, WC; Orton, KC; Rhoads, RE; Sonenberg, N; Traugh, JA; Waskiewicz, AJ | 1 |
| Ahel, I; Blum, P; Ibba, M; Korencic, D; Ruan, B; Sacher, M; Schelert, J; Söll, D; Stathopoulos, C | 1 |
| Comer, FI; Hart, GW; Kreppel, LK; Wadzinski, BE; Wells, L | 1 |
| Chadee, DN; Kyriakis, JM | 1 |
| Leonard, M; Schmid, SL; Song, BD | 1 |
| Inoue, H; Kanazawa, H; Kuwabara, N; Nakamura, N; Tsuboi, Y | 1 |
| Hyman, BT; Liu, CX; Migliorini, MM; Mikhailenko, I; Peltan, ID; Ranganathan, S; Strickland, DK; Von Arnim, CA | 1 |
| Allen, JA; Maly, DJ; Shokat, KM | 1 |
| Ksiezak-Reding, H; Kyoung Pyo, H; Lovati, E; Pasinetti, GM | 1 |
| Gautier, N; Hinault, C; Lawrence, JC; Mothe-Satney, I; Van Obberghen, E | 1 |
| Ahn, NG; Giddings, TH; Huneycutt, BJ; Jaspersen, SL; Resing, KA; Winey, M | 1 |
| Beausoleil, SA; Cantley, LC; Cohn, MA; Elias, JE; Gygi, SP; Jedrychowski, M; Li, J; Schwartz, D; Villén, J | 1 |
| Lesage, G; Lu, X; Merikhi, A; Roundtree, M; Shentu, S; Xia, X | 1 |
| Brattain, MG; Cookson, MM; Hauser, J; Sawhney, RS; Sharma, B | 1 |
| Bernard, MP; Cao, D; Lin, W; Moyle, WR; Myers, RV; Xing, Y | 1 |
| Gorter, G; Willem Akkerman, J | 1 |
| Chang, LI; Chen, PR; Hsiao, KM; Jou, SB; Pan, H | 1 |
| Copeland, TD; Johnson, PF; Kaldis, P; Sebastian, T; Shuman, JD; Smart, RC; Zhu, S | 1 |
| Allen-Baume, V; Ball, A; Cockcroft, S; Larijani, B; McDonald, N; Morgan, CP; Morrice, N; Murray-Rust, J; Sapkota, G; Segui, B; Skippen, A | 1 |
| Fujimoto, K; Fukui, H; Horio, S; Kato, T; Ogawa, M | 1 |
| Chatterjee, BP; Chatterjee, U; Singh, T; Wu, AM; Wu, JH | 1 |
| Környei, JL; Kovács, KA; Lengyel, F; Sumegi, B; Vértes, M; Vértes, Z | 1 |
| Burnham, DJ; Corzo, A; Kerr, BJ; Kidd, MT | 1 |
| Chaudhary, LC; McKain, N; Miyagawa, E; Walker, ND; Wallace, RJ | 1 |
| Filipenko, ML; Glushkov, AN; Gorbunova, EV; Khrapov, EA; Kinsht, VN; Krasnov, VA; Norkina, OV; Shabaldin, AV; Vikhrova, MA; Voronina, EN | 1 |
| Haché, RJ; Schild-Poulter, C; Soubeyrand, S | 1 |
| Chu, X; Li, D; Li, P; Liu, X; Yu, W | 1 |
| Holmes, CF; Perreault, KR; Plummer, G; Posse De Chaves, EI | 1 |
| Allen, GS; Brennan, RG; Diel, M; Hillen, W; Schumacher, MA; Seidel, G | 1 |
| Gupta, D; Khandelwal, RL; Roesler, WJ; Syed, NA | 1 |
| Da Silva, P; Duclos, S; Piller, F; Piller, V; Vovelle, F | 1 |
| Avci, H; Herkner, A; Kotzka, J; Lehr, S; Meyer, HE; Muller-Wieland, D; Sickmann, A | 1 |
| Brewer, D; Dobransky, T; Doherty-Kirby, A; Kim, AR; Lajoie, G; Rylett, RJ | 1 |
| GUNSALUS, IC; WOOD, WA | 1 |
| van der Donk, WA; Xie, L | 1 |
| Arrigoni, G; Marin, O; Meggio, F; Pagano, MA; Paolin, B; Pinna, LA; Settimo, L | 1 |
| Barcia, R; Blanco, S; Lazo, PA; Santos, CR; Vega, FM | 1 |
| Fujiwara, T; Kasajima, I; Naito, S; Ohkama-Ohtsu, N | 1 |
| Cormack, BP; Frieman, MB | 1 |
| Biggs, JR; Kraft, AS; Zhang, Y | 1 |
| Douglas, P; Kurz, EU; Lees-Miller, SP | 1 |
| Zick, Y | 1 |
| Grammatopoulos, DK; Hillhouse, EW; Levine, MA; Markovic, D; Teli, T | 1 |
| Parker, GE; Rhodes, SJ; West, BE; Witzmann, FA | 1 |
| Brautigan, DL; Tountas, NA | 1 |
| Chen, S; Oncel, D; Shu, H; Tang, Z; Yu, H | 1 |
| Cushman, SW; Kondapaka, SB; Sausville, EA; Yver, DR; Zarnowski, M | 1 |
| Kaneki, M; Martyn, JA; Sugita, H; Sugita, M; Yasuhara, S; Yasukawa, T | 1 |
| Bode, AM; Cho, YY; Choi, HS; Dong, Z; He, Z; Ma, WY | 1 |
| Eraso, P; Falcón-Pérez, JM; Martínez-Burgos, M; Mazón, MJ; Portillo, F | 1 |
| Arguello, M; Hiscott, J; Lin, R; Penafuerte, C; Yang, L | 1 |
| Carpena, X; Deemagarn, T; Fita, I; Loewen, PC; Singh, R; Wiseman, B | 1 |
| Colman, RF; Kim, TK | 1 |
| Ben-Amotz, D; Davisson, VJ; Ortiz, C; Xie, Y; Zhang, D | 1 |
| Longhi, R; Massari, S; Pietrini, G; Rosa, P; Vanoni, C | 1 |
| Stern, DF; Tsvetkov, L | 1 |
| Harris, PL; Lee, HG; Moreira, P; Perry, G; Smith, MA; Webber, KM; Zhu, X | 1 |
| Balschi, JA; Frederich, M; Zhang, L | 1 |
| Burlingame, AL; Chalkley, RJ; Hansen, KC; Hart, GW; Trinidad, JC; Vosseller, K; Wells, L | 1 |
| Brandt, GS; Dougherty, DA; Imperiali, B; Petersson, EJ; Rothman, DM; Vázquez, ME | 1 |
| Arora, A; Choe, ES; Fibuch, EE; Liu, Z; Mao, L; Wang, JQ; Yang, L; Zhang, G | 1 |
| Chun, JS; Kim, JS; Park, ZY; Yoo, YJ; Yu, SS | 1 |
| Duell, K; Konopka, JB; Lin, JC; Saracino, M | 1 |
| Ball, LE; Crouch, RK; Ervin, LA; Schey, KL | 1 |
| Asaithamby, A; Botvinick, E; Burma, S; Chan, DW; Chen, BP; Chen, DJ; Kobayashi, J; Morotomi-Yano, K; Qin, J | 1 |
| Brooks, J; Campos-González, R; Reynolds, AB; Xia, X | 1 |
| Camp, SM; Chiang, ET; Dudek, SM; Finigan, JH; Garcia, JG; Jacobson, JR; Singleton, PA; Ye, SQ | 1 |
| Kauw, JJ; Klompmaker, R; Lindon, C; Medema, RH; Rozendaal, MJ; van de Weerdt, BC; van Vugt, MA; Wolthuis, RM | 1 |
| Hinou, H; Kurogochi, M; Matsushita, T; Nishimura, S; Shimizu, H | 1 |
| Choi, SJ; Choi, SW; Firatli, E; Hart, PS; Hart, TC; Ryu, OH; Shen, RF; Wang, G; Wu, WW | 1 |
| Goold, RG; Gordon-Weeks, PR; Marsh, P; Trivedi, N; Wood-Kaczmar, A | 1 |
| Addicks, GC; Atlas, E; Carrigan, A; Edgecombe, A; Haché, RJ; Lamprecht, C; Lefebvre, YA; Rouleau, Y; Visentin, L; Walther, RF | 1 |
| Hu, Z; Lelli, KM; Maines, MD; Miralem, T; Torno, MD | 1 |
| Cano, E; Ortega-Pérez, I; Redondo, JM; Vázquez, J; Villar, M; Were, F | 1 |
| Beugnet, A; Murakami, M; Proud, CG; Wang, X; Yamanaka, S | 1 |
| Crépieux, P; Fontaine, I; Gauthier, C; Guillou, F; Kara, E; Lécureuil, C; Martinat, N; Reiter, E; Sow, A; Tesseraud, S | 1 |
| Campbell, KJ; Garrett, MD; Perkins, ND; Rocha, S; Schumm, K | 1 |
| Aizawa, T; Demura, M; Kamo, N; Kikukawa, T; Kubo, M; Nitta, K; Sato, M | 1 |
| Kählig, H; Kolarich, D; Kosma, P; Messner, P; Schäffer, C; Scheberl, A; Zayni, S | 1 |
| Juhnn, YS; Kang, UG; Kim, SY; Kim, Y; Kim, YS; Lee, YI; Seo, M | 1 |
| Copik, AJ; Johnson, BH; Kumar, R; Miller, AL; Thompson, EB; Wang, Y; Webb, MS | 1 |
| Baran, V; Kalous, J; Kubelka, M; Motlik, J; Schultz, RM; Solc, P | 1 |
| Huq, MD; Khan, SA; Park, SW; Wei, LN | 1 |
| Bao, M; Clauser, K; Conley, PB; Hart, MJ; Komuves, L; Lin, H; Nanda, N; Phillips, DR; Quertermous, T | 1 |
| Baer, R; Choudhury, AD; Ludwig, T; Modi, AP; Xu, H; Zhang, W | 1 |
| Koshland, DE; Kwan, G; Lu, CJ; Radisky, ES | 1 |
| Ishihara, K; Kondo, R; Sakakura, A | 1 |
| Doctor, RB; Finnigan, C; Fouassier, L; Gidey, E; Housset, C; Howell, KE; McWilliams, RR; Nichols, MT; Robin, H | 1 |
| Liu, B; Qin, F; Zhang, C | 1 |
| Asami, T; Clouse, SD; Goshe, MB; Huber, SC; Kuchar, JA; Li, J; Phinney, BS; Soderblom, EJ; Wang, X; Yoshida, S | 1 |
| Blenis, J; Holz, MK | 1 |
| Brennesvik, EO; Jebens, E; Jensen, J; Ktori, C; Ruzzin, J; Shepherd, PR | 1 |
| Gamblin, TC; Rankin, CA; Sun, Q | 1 |
| Barthet, G; Bockaert, J; Claeysen, S; Dumuis, A; Framery, B; Gaven, F; Nakamura, T; Shinjo, K | 1 |
| Cohen, MS; Shokat, KM; Taunton, J; Zhang, C | 1 |
| Behring, A; Goyal, P; Pandey, D; Siess, W | 1 |
| Hermosilla, R; Kuna, M; Neuschäfer-Rube, F; Pathe-Neuschäfer-Rube, A; Püschel, GP; Schülein, R | 1 |
| Bloch, DB; Brooks, SA; Collins, J; Connolly, JE; Rigby, S; Rigby, WF; Roy, K | 1 |
| Bowser, MT; Miller, RF; O'Brien, KB | 1 |
| Bontems, S; Di Valentin, E; Habran, L; Piette, J; Sadzot-Delvaux, C | 1 |
| Cleghon, V; Lochhead, PA; Morrice, N; Sibbet, G | 1 |
| Eychène, A; Felder-Schmittbuhl, MP; Gillet, S; Girault, JA; Lecoin, L; Pouponnot, C; Sii-Felice, K | 1 |
| Berne, GP; de Graaf, KL; Hansson, GK; Herrmann, MM; Olsson, T; Weissert, R | 1 |
| Cheifetz, MN; Fridkin, M; Millar, RP; Naor, Z; Pawson, AJ; Shacham, S | 1 |
| Macias, MJ; Martin-Malpartida, P; Morales, B; Royo, M; Shaw, AZ; Yraola, F | 1 |
| Ferrer, I; Puig, B; Rey, MJ | 1 |
| Allgaier, C; Camins, A; Canudas, AM; Garcia de Arriba, S; Jiménez, A; Jordà, EG; Pallàs, M; Verdaguer, E | 1 |
| Burbach, JP; Hoekman, MF; Jacobs, FM; Smidt, MP; van der Heide, LP | 1 |
| Chow, MC; Chung, AY; Denslow, ND; Harmon, AC; McClung, SH; Prokai, L; Stevens, SM; Strachan, CN | 1 |
| Aulabaugh, A; Chaudhary, D; Czerwinski, R; Greco, RM; Huang, Y; Kriz, R; Lin, L; Liu, L; Malakian, K; Olland, S; Stahl, M; Wolfrom, S | 1 |
| Dong, LQ; Liu, F | 1 |
| Barati, MT; Gozal, D; Gozal, E; Kausar, H; Klein, JB; Rane, MJ; Sachleben, LR; Trent, JO; Wu, R | 1 |
| Burns, KA; Gray, JP; Leas, TL; Perdew, GH; Vanden Heuvel, JP | 1 |
| Biggs, JR; Garcia, M; Kraft, AS; Peterson, LF; Zhang, DE; Zhang, Y | 1 |
| Boss, GR; Chen, Y; Pilz, RB; Zhao, X; Zhuang, S | 1 |
| Ishimi, Y; Lees, E; Tanudji, M; Zhu, Y | 1 |
| Nakashima, T; Okada, A; Sokabe, M; Tanaka, I; Yao, M | 1 |
| Fukazawa, Y; Gao, Y; Hamabe, W; Kishioka, S; Kumamoto, K; Maeda, T; Ozaki, M | 1 |
| Hatano, N; Ichimura, T; Inuzuka, H; Kobayashi, R; Nozaki, N; Sueyoshi, Y; Tokumitsu, H; Yokokura, S | 1 |
| Al-Khouri, AM; Ma, Y; Mustelin, T; Togo, SH; Williams, S | 1 |
| Cohen, P; Cuomo, ME; Knebel, A; Mittnacht, S; Morrice, N; Platt, G | 1 |
| Barratt, CL; Björndahl, L; Brewis, IA; Jha, KN; Lefièvre, L; Moseley, FL; Publicover, SJ | 1 |
| Brunet, A; David-Dufilho, M; Millanvoye-Van Brussel, E; Rendu, F; Topal, G; Walch, L | 1 |
| Ballard, DW; Carter, RS; Gomez, RJ; Khan, WN; Kray, AE; Llanes, JM; Pennington, KN; Sanders, LE; Wadzinski, BE | 1 |
| Chung, CK; Jeon, WJ; Juhnn, YS; Kang, UG; Kim, Y; Kim, YS; Park, JB | 1 |
| Gu, S; Ji, C; Jin, Z; Mao, Y; Wu, M; Xie, Y; Xu, J; Zheng, H; Zou, X | 1 |
| Cho, SG; Suresh Babu, CV; Yoo, YS | 1 |
| Nagy, PD; Shapka, N; Stork, J | 1 |
| Järviluoma, A; Ojala, PM; Sarek, G | 1 |
| Bonner, ER; Cahoon, RE; Jez, JM; Knapke, SM | 1 |
| Lin, A; Liu, J; Yu, C; Zhang, J | 1 |
| Liu, Y; Miltyk, W; Phang, JM; Surazynski, A | 1 |
| Cao, D; Cheng, H; Hussain, A; Peng, J; Wen, Z | 1 |
| Bellini, G; Coppola, G; Del Giudice, EM; Longaretti, F; Pascotto, A; Taglialatela, M; Veggiotti, P | 1 |
| Addicks, K; Baumann, MA; Bloch, W; Korkmaz, Y; Raab, WH; Schneider, K | 1 |
| Misra, UK; Pizzo, SV | 1 |
| Chen, CS; Lin, HP; Tseng, PH; Weng, SC | 1 |
| Davis, TA; Suryawan, A | 1 |
| Arena, S; D'Adamio, L; D'Ambrosio, C; Fulcoli, G; Scaloni, A; Scheinfeld, MH; Zhou, D | 1 |
| Dilworth, SM; Horman, S; Hussain, N; Rider, MH; Storey, KB | 1 |
| Pochynyuk, O; Staruschenko, A; Stockand, JD | 1 |
| Birnbaum, MJ; Bruce, CR; Carey, AL; Febbraio, MA; Hawley, JA; Monks, R; Southgate, RJ; Steinberg, GR; Walder, K; Watt, MJ | 1 |
| Beullens, M; Bollen, M; Ceulemans, H; Derua, R; Morrice, N; Vancauwenbergh, S; Waelkens, E | 1 |
| Dihazi, H; Eschrich, K; Flehmig, G; Fürst, S; Gerevich, Z; Illes, P; Nörenberg, W; Stanchev, D; Wirkner, K | 1 |
| Lee, AM; Robinson, DA; Westfall, MV | 1 |
| Greenwald, I; Shaye, DD | 1 |
| Cho, W; Hwang, JH; Johnson, KR; Kim, JH; Obeid, LM; Park, ZY; Stahelin, RV | 1 |
| Ball, LE; Berkaw, MN; Buse, MG | 1 |
| Ivarsson, Y; Mannervik, B | 1 |
| Bugayenko, A; Day, BW; Irani, K; Kasuno, K; Khanday, FA; Mattagajasingh, I; Nabi, N; Naqvi, A; Santhanam, L; Yamamori, T; Zhang, Z | 1 |
| Brame, CJ; Horwitz, AR; Hunt, DF; Schroeder, MJ; Shabanowitz, J; Webb, DJ; Whitmore, L | 1 |
| Grigera, PR; Hunt, DF; Jeffery, ED; Martin, KH; Parsons, JT; Shabanowitz, J | 1 |
| Dirksen, EH; Elgersma, RC; Heck, AJ; Liskamp, RM; Rijkers, DT; Ruijter, E; Slijper, M; van der Veken, P | 1 |
| Imoto, M; Kajioka, T; Kosuga, S; Shimizu, Y; Tashiro, E; Ueki, M | 1 |
| Conrad, M; Kerby, RL; Roberts, GP; Youn, H | 1 |
| Gong, CX; Grundke-Iqbal, I; Iqbal, K; Liu, F | 1 |
| Britton, WJ; Clarke, AL; Dao-Ung, LP; Fernando, SL; Fuller, SJ; Gu, BJ; Petrou, S; Saunders, BM; Shemon, AN; Skarratt, KK; Sluyter, R; Tan, KS; Wiley, JS | 1 |
| Bergh, S; de Groot, JF; Koul, D; Liu, TJ; Lu, Y; Mills, GB; Shen, R; Yung, WK | 1 |
| Eom, KD; Tam, JP | 1 |
| Fujimoto, H; Imamura, M; Kato, N; Kondo, T; Kosugi, A; Minami, Y; Oishi, I; Onishi, N; Takekawa, M; Xu, XZ; Yoda, A | 1 |
| Countryman, J; El-Guindy, AS; Miller, G; Paek, SY | 1 |
| Fisone, G; Galdi, S; Greengard, P; Håkansson, K; Hendrick, J; Snyder, G | 1 |
| Cotter, PD; Deegan, LH; Draper, LA; Hill, C; Lawton, EM; O'Connor, PM; Ross, RP | 1 |
| Carling, D; Heath, R; Horman, S; Hue, L; Mouton, V; Neumann, D; Rider, MH; Schlattner, U; Vertommen, D; Wallimann, T; Woods, A | 1 |
| Allen, KE; Lecchi, S; Mason, AB; Pardo, JP; Slayman, CW | 1 |
| Böcker, U; Feick, P; Haas, SR; Singer, MV | 1 |
| Gall, AL; Pavletich, NP; Rubin, SM; Zheng, N | 1 |
| An, WL; Benedikz, E; Götz, J; Nishimura, T; Norberg, J; Pei, JJ; Winblad, B; Zhou, XW | 1 |
| Boknik, P; Grosse Hartlage, M; Hanske, G; Meissner, A; Neumann, J; Schmitz, W; Van Aken, H; Weber, T | 1 |
| Inanami, O; Kawahara, K; Kuwabara, M; Nakajima, T; Nomura, Y; Okuma, Y; Wakasa, T | 1 |
| Abe, Y; Akiyama, H; Miyamoto, A; Sasada, H; Sato, E; Shimizu, T; Uchida, T | 1 |
| Bosch, R; Farías, G; Fuentes, P; Guillón, M; Lavados, M; Maccioni, RB; Mujica, C | 1 |
| Garcia, GA; Todorov, KA | 1 |
| Kodama, H; Liu, G; Manabe, M; Song, SJ; Yagi-Chaves, SN; Yamashita, K | 1 |
| Adams, DG; Brayer, KJ; Fritz, A; McCormick, N; Vaillancourt, RR; Wadzinski, BE | 1 |
| Kalabis, J; Podolsky, DK; Rosenberg, I | 1 |
| Peter-Katalinić, J | 1 |
| Amouyel, P; Arveiler, D; Bingham, A; Dallongeville, J; Delcroix, AG; Ducimetière, P; Ferrières, J; Meirhaeghe, A; Ruidavets, JB; Wagner, A | 1 |
| Ahmad, I; Hoessli, DC; Rafik, SM; Shakoori, AR; Walker-Nasir, E | 1 |
| Cripps, D; Davies, P; Jeng, Y; Thomas, SN; Yang, AJ; Yang, F | 1 |
| Fukushi, S; Kurane, I; Mizutani, T; Morikawa, S; Saijo, M | 1 |
| Kim, JI; Shen, Y; Song, PS | 1 |
| Chen, X; Liu, GZ; Pi, LY; Song, WY; Tinjuangjun, P; Wang, YS; Xu, WH | 1 |
| Baroni, MG; Cavallo, MG; Fanelli, M; Filippi, E; Romeo, S; Sentinelli, F | 1 |
| Freel, CD; Haystead, TA; Kornbluth, S; Margolis, SS; Perry, JA; Weitzel, DH; Yoshida, M | 1 |
| Browning, D; Dulin, NO; Qin, Y; Sandbo, N; Taurin, S | 1 |
| Edelson-Averbukh, M; Lehmann, WD; Pipkorn, R | 2 |
| Absalon, C; Courtney, P; Garin, J; Jackson, P; Kuhn, L; Labas, V; Lévine, A; Scrivener, E; Séror, SJ; Vannier, F; Vinh, J | 1 |
| Nichols, RJ; Traktman, P; Wiebe, MS | 1 |
| Carroll, CA; Luo, M; Mandarino, LJ; Reyna, SM; Weintraub, ST; Yi, Z | 1 |
| Guo, D; Huang, XY; Maack, T; Madhusoodanan, KS; McGarrigle, DK | 1 |
| Danek, EI; Lamarche-Vane, N; Stenne, R; Tcherkezian, J; Triki, I | 1 |
| Banach, M; Błaszczak, R; Ciałkowska-Rysz, A; Grycewicz, T; Guga, P; Kujawski, K; Luciak, M; Markuszewski, L; Olszewski, R; Rysz, J | 1 |
| Greengard, P; Ho, A; Kreek, MJ; Nairn, AC; Picetti, R; Schlussman, SD; Svenningsson, P; Zhang, Y | 1 |
| Mikoshiba, K; Morimura, T; Ogawa, M; Ohshima, T; Suzuki, H | 1 |
| Beerman, TA; Kennedy, DR | 1 |
| Ivarsson, Y; Mannervik, B; Norrgård, MA; Tars, K | 1 |
| Bo, T; Han, NY; Hautala, JT; Riekkola, ML; Wiedmer, SK | 1 |
| Degrado, WF; Lear, JD; Nanda, V; Tatko, CD | 1 |
| Gu, HH; Han, DD; Wu, X | 1 |
| Hedvat, CV; Koff, A; Liu, Y; Mao, S; Nguyen, H; Nimer, SD; Yao, J; Zhu, XH | 1 |
| Horstkorte, R; Matthias, S | 1 |
| Issinger, OG; Olsen, BB; Petersen, J | 1 |
| He, X; Wu, G | 1 |
| Cimino, DF; Maestas, DC; Potter, RM; Prossnitz, ER | 1 |
| Gou, BD; Huang, J; Luo, LY; Wang, K; Zhang, TL | 1 |
| Alessi, DR; Deak, M; Karlsson, HK; Morrice, NA; Rafiqi, FH; Thastrup, J; Vitari, AC | 1 |
| Baird, TT; Craik, CS; Wright, WD | 1 |
| Ahel, D; Ban, N; Bilokapic, S; Gruic-Sovulj, I; Maier, T; Söll, D; Weygand-Durasevic, I | 1 |
| Merkulova, NA; Perova, AA; Sedova, VM; Solodovnikova, AS | 1 |
| Carper, E; Etzkorn, FA; Poutsma, JC; Poutsma, JL; Schroeder, OE; Wind, JJ | 1 |
| Biron, E; Chatterjee, J; Kessler, H | 1 |
| Kodama, H; Liu, G; Manabe, M; Masuoka, N; Yamashita, K; Zhang, J | 1 |
| Addicks, K; Baumann, MA; Bloch, W; Korkmaz, Y; Raab, WH; Schneider, K; Steinritz, D | 1 |
| Ball, HL; Goldsmith, EJ; Keitany, G; Li, Y; Mukherjee, S; Orth, K; Wang, Y | 1 |
| Dixon, JE; Worby, CA | 1 |
| Arendt, T; Grosche, J; Härtig, W; Hoffmann, R; Lehmann, J; Singer, D; Stieler, J | 1 |
| Annamalai, B; Gether, U; Jayanthi, LD; Ramamoorthy, S; Samuvel, DJ | 1 |
| Rees, MW | 1 |
| Borch, J; Harthill, JE; Mackintosh, C; Meek, SE; Morrice, N; Peggie, MW; Wong, BH | 1 |
| Bednorz, A; Didié, M; Ditz, D; Dobrev, D; El-Armouche, A; Eschenhagen, T; Pamminger, T | 1 |
| Bockstaele, L; Coulonval, K; de Launoit, Y; Dumont, JE; Kooken, H; Libert, F; Paternot, S; Roger, PP | 1 |
| Chamberlin, AR; Colby, DA | 1 |
| Frey, TK; Hobman, TC; Ilkow, CS; Law, LJ; Rawluk, M; Stuart, DT; Tzeng, WP | 1 |
| Arias, EB; Cartee, GD; Hamada, T | 1 |
| Doi, J; Katoh, Y; Lin, XZ; Min, L; Miyauchi, A; Muraoka, M; Nakamura, H; Okamoto, M; Satoh, T; Takemori, H; Tamura, M; Tsuchiya, Y; Witters, LA | 1 |
| Davis, S; Dufour, F; Horwood, JM; Laroche, S | 1 |
| Bowen, S; Wheals, AE | 1 |
| Kanaori, K; Kunugi, S; Lee, YF; Tada, T; Tanaka, N; Tani, Y | 1 |
| Asensio, JL; Avenoza, A; Busto, JH; Corzana, F; Engelsen, SB; Jiménez-Barbero, J; Peregrina, JM | 1 |
| Akkari, Y; Cunningham, M; Fan, G; Malempati, S; Olson, S; Sears, RC; Tibbitts, D | 1 |
| Crépieux, P; Gauthier, C; Guillou, F; Kara, E; Martinat, N; Piketty, V; Reiter, E | 1 |
| Ginsberg, MH; Haslett, C; Hodkinson, PS; Lad, Y; Mackinnon, AC; McHugh, B; Sethi, T | 1 |
| Archambaud, C; Cossart, P; Dussurget, O; Nahori, MA; Pizarro-Cerda, J | 1 |
| Buescher, JL; Cerny, RL; Ikezu, T; Sato, S | 1 |
| Durkin, SS; Fryrear, KA; Semmes, OJ; Ward, MD | 1 |
| Ebel, M; Rehder, D | 1 |
| Carnahan, RH; Reynolds, AB; Vaughan, MH; Wildenberg, GA; Xia, X | 1 |
| D'Andrea, AD; Ho, GP; Margossian, S; Taniguchi, T | 1 |
| Anfora, AT; Welch, RA | 1 |
| Gao, YT; Martásek, P; Masters, BS; Panda, SP; Roman, LJ; Salerno, JC | 1 |
| Bai, X; Jiang, W; Jiao, R; Jin, Z; Li, X; Tian, W; Wu, H; Xu, M; Yang, Y; Zhao, G; Zhu, Y | 1 |
| Ibe, BO; John, TA; Usha Raj, J | 1 |
| Guallar, V; Hammes-Schiffer, S; Small, YA; Soudackov, AV | 1 |
| Chung, KC; Kim, HJ; Kim, J; Lee, CH; Lee, D; Paik, SR | 1 |
| Dib-Hajj, SD; Lampert, A; Tyrrell, L; Waxman, SG | 1 |
| Kantrowitz, ER; Wang, J | 1 |
| Adhya, S; Bair, CL; Carrier, F; Charpentier, TH; Lee, A; Lin, J; Liriano, M; Oppenheim, AB; Varney, KM; Weber, DJ; Wilder, PT; Yang, D | 1 |
| Chen, D; de Jesús Pérez, J; García, JA; Hartweck, LM; Olszewski, NE; Scott, CL | 1 |
| Fanning, E; Klimovich, V; Nievera, CJ; Olson, E; Wu, X | 1 |
| Birk, JB; Wojtaszewski, JF | 1 |
| Morris, AP; Sellin, JH; Umar, S; Wang, Y | 1 |
| Muma, NA; Shi, J; Zemaitaitis, B | 1 |
| Li, L; Liu, Z; Shen, S; Shi, H; Sun, H | 1 |
| Epa, VC; Gorman, JJ; McKern, NM; Robinson, CP; Sparrow, LG; Strike, PM; Ward, CW | 1 |
| Agid, Y; Anheim, M; Brice, A; Charles, P; Czernecki, V; Dürr, A; Lesage, S; Lohmann, E; Pollak, P; Schüpbach, M; Welter, ML; Worbe, Y; Yaici, S | 1 |
| Bang, JK; Garfield, S; Kang, YH; Lee, KS; Park, JE; Seong, YS; Soung, NK; Veenstra, TD; Yu, H; Yu, LR; Yun, SM | 1 |
| Mansuy, IM; Shenolikar, S | 1 |
| Arnon, R; Gold, D; Hanoch, T; Jeon, SH; Pauli, H; Seger, R; Tarrab-Hazdai, R | 1 |
| Cardinaux, JR; Ceseña, TI; Kwok, R; Schwartz, J | 1 |
| Battegay, EJ; Hall, MN; Humar, R; Li, W; Molle, KD; Petrimpol, M | 1 |
| Chen, X; Heard, PA; Mandal, PK; McMurray, JS; Ren, Z | 1 |
| Srivastava, A; Wu, J; Zhao, W; Zhong, L | 1 |
| Candeletti, S; D'Addario, C; Di Benedetto, M; Romualdi, P | 1 |
| García-Borrón, JC; Jiménez-Cervantes, C; Sánchez-Laorden, BL | 1 |
| Almgren, P; Berglund, G; Fava, C; Guidi, GC; Melander, O; Montagnana, M; Rosberg, L | 1 |
| Dirksen, EH; Heck, AJ; Liskamp, RM; Nuijens, T; Poot, AJ; Rijkers, DT; Ruijter, E; Slijper, M | 1 |
| Armas, P; Calcaterra, NB; Lombardo, VA; Weiner, AM | 1 |
| Chen, BP; Chen, DJ; Kobayashi, J; Krempler, A; Lerenthal, Y; Löbrich, M; Shiloh, Y; Uematsu, N; Yajima, H | 1 |
| Dolezal, V; Jakubík, J | 1 |
| Fliegel, L; Li, L; Malo, ME | 1 |
| Kay, EP; Lee, JG | 2 |
| Israël, A; Lobry, C; Lopez, T; Weil, R | 1 |
| Haché, RJ; Schild-Poulter, C; Sharp, PA; Shih, A; Soubeyrand, S; Tantin, D; Yarymowich, NC | 1 |
| Gnad, F; Jensen, PR; Kumar, C; Macek, B; Mann, M; Mijakovic, I; Olsen, JV | 1 |
| Antonny, B; Boehmer, T; Casella, JF; Drin, G; Gautier, R; Schwartz, TU | 1 |
| Pellegrino, MJ; Stork, PJ | 1 |
| Driessen, AJ; Kluskens, LD; Kuipers, A; Kuipers, OP; Moll, GN; Rink, R; Wierenga, J | 1 |
| Av-Gay, Y; Papavinasasundaram, KG; Zheng, X | 1 |
| Elias, BC; Rao, R; Seth, A; Sheth, P | 1 |
| Nau, WM; Sahoo, H | 1 |
| Cédrin-Durnerin, I; Czernichow, C; Hugues, JN; Pasquier, M; Théron-Gérard, L | 1 |
| Aubagnac, JL; Enjalbal, C; Martinez, J; Mouls, L | 1 |
| Cashman, MA; Colman, RF; Segall, ML | 1 |
| Guss, JM; Lee, M; Maher, MJ | 1 |
| Bu, X; Fang, L; Han, S; Huang, P; Li, J; Qi, Z; Zhang, N | 1 |
| Baldwin, SA; Casagrande, F; del Rio, C; Fotiadis, D; Gelpí, JL; Henderson, PJ; Palacín, M; Ratera, M; Reig, N; Torrents, D; Xie, H; Zorzano, A | 1 |
| Anandatheerthavarada, HK; Avadhani, NG; Fang, JK; Galati, D; Prabu, SK; Raza, H; Sepuri, NB; Spear, J | 1 |
| Agid, Y; Bonnet, AM; Borg, M; Brice, A; Broussolle, E; Damier, P; Destée, A; Durif, F; Dürr, A; Janin, S; Layet, V; Leclere, L; Lesage, S; Leutenegger, AL; Lohmann, E; Martinez, M; Penet, C; Pollak, P; Rasco, O; Thobois, S; Tison, F; Tranchan, C; Vérin, M; Viallet, F; Vidailhet, M | 1 |
| Bordonaro, M; Lazarova, DL; Sartorelli, AC | 1 |
| Buscemi, G; Carlessi, L; Delia, D; Hong, Z; Larson, G; Wu, JZ | 1 |
| Basbous, J; Chalbos, D; Hipskind, R; Jariel-Encontre, I; Piechaczyk, M | 1 |
| Kornreich, BG; Niu, L; Oswald, RE; Roberson, MS | 1 |
| Hao, YH; Mukherjee, S; Orth, K | 1 |
| Chen, G; Kranias, EG; Mitton, B; Nicolaou, P; Rodriguez, P | 1 |
| Anandan, B; Jayaraman, G; Karthikeyan, M; Rose, R | 1 |
| Abe, T; Liang, S; Matsui, H; Oda, Y; Takei, K; Tanabe, K; Tomizawa, K; Wei, FY; Wu, YM; Yamada, H; Yoshida, Y | 1 |
| Hao, B; Harper, JW; Oehlmann, S; Pavletich, NP; Sowa, ME | 1 |
| Bredenkamp, N; Illing, N; Papalopulu, N; Regad, T; Roth, M | 1 |
| Hanada, K; Kawano, M; Kumagai, K; Nishijima, M; Shinkai-Ouchi, F | 1 |
| Arnould, S; Blanco, FJ; Epinat, JC; Montoya, G; Padró, D; Pâques, F; Prieto, J; Redondo, P | 1 |
| Baldwin, EP; Carman, GM; Chang, YF; Martin, SS | 1 |
| Chua, WJ; Hansen, TH; Herr, RA; Lybarger, L; Wang, X; Wiertz, EJ | 1 |
| Lees-Miller, SP; Povirk, LF; Ramsden, DA; Valerie, K; Zhou, RZ | 1 |
| Fujiwara, N; Iwai, K; Ueta, R; Yamaguchi-Iwai, Y | 1 |
| Bateup, H; Silver, R; Svenningsson, P; Witkovsky, P; Yan, L | 1 |
| Bird, MJ; Cheng, HC; Crowhurst, MO; Gajewski, JE; Liu, J; Sio-Seng Lio, D; Wettenhall, RE; Zhu, HJ | 1 |
| Huang, Y; Jiang, LY; Rong, R; Sheikh, MS | 1 |
| Hung, CW; Krüger, R; Lehmann, WD; Salek, M; Weckwerth, W; Wolschin, F | 1 |
| Fukasawa, K; Izumi, H; Kanai, M; Kim, SH; Ma, Z; Mattison, CP; Winey, M | 1 |
| Copps, KD; Dong, X; Dunn, SL; Feener, EP; Giraud, J; Haas, M; White, MF | 1 |
| Cao, Y; Guo, L; Hu, D; Li, L; Li, Z; Luo, W; Tang, M; Tao, Y; Tsao, SW; Wang, Z; Xiao, L; Yi, W; Zhou, S | 1 |
| Ross, AR | 1 |
| Mazurek, J; Overhand, M; Overkleeft, HS; Risseeuw, MD; van der Marel, GA; van Langenvelde, A | 1 |
| Asensio, JL; Avenoza, A; Busto, JH; Corzana, F; García de Luis, M; Jiménez-Barbero, J; Jiménez-Osés, G; Peregrina, JM | 1 |
| Abe, Y; Akagawa, Y; Hiasa, K; Suzuki, K; Taji, T; Yoshida, Y | 1 |
| Knapp, S; Oliver, AW; Pearl, LH | 1 |
| Hayward, SD; Liao, G; Liu, J; Martin, HJ | 1 |
| Alzari, PM; Bellinzoni, M; Shepard, W; Wehenkel, A | 1 |
| Ni, W; van der Donk, WA; Zhang, X | 1 |
| Aguilar, HC; Chu, D; Lee, B; Negrete, OA | 1 |
| Tarelli, E | 1 |
| Aramata, S; Han, SI; Kataoka, K; Yasuda, K | 1 |
| Herlevsen, MC; Theodorescu, D | 1 |
| Kitayama, Y; Kiyohara, R; Kondo, T; Nishiwaki, T; Satomi, Y; Takao, T; Terauchi, K | 1 |
| Fukumoto, Y; Johnson, KR; Reynolds, AB; Shintani, Y; Wheelock, MJ | 1 |
| Becher, D; Bernhardt, J; Eymann, C; Gronau, K; Hecker, M; Klutzny, A | 1 |
| Liu, H; Pattabiraman, VR; Vederas, JC | 1 |
| Barany, G; Borgert, A; Liu, M; Live, D | 1 |
| Cho, H; Choe, S; Hwang, I; Kim, K; Park, J; Ryu, H | 1 |
| Dong, Y; Song, P; Wu, Y; Xie, Z; Xu, J; Zhang, M; Zou, MH | 1 |
| Nishikaze, T; Takayama, M | 1 |
| Bahr, SM; Brat, D; Gutmann, DH; Jang, SW; Liu, Z; Sun, SY; Tang, X; Wang, X; Ye, K | 1 |
| Ahn, YS; Cheon, YH; Cho, HJ; Chung, SH; Jeong, HK; Kim, IS; Lee, HW; Radnaabazar, C; Ryoo, SR; Song, WJ; Yoo, JJ | 1 |
| Chatham, JC; Fülöp, N; Marchase, RB; Nöt, LG | 1 |
| Johansson, S; Stefansson, A; Velling, T | 1 |
| Alvarez-Arias, DA; Campbell, KS | 1 |
| Ayer, G; Barton, B; Maughan, DW; Vigoreaux, JO | 1 |
| Gross, J; King, JB; Lovly, CM; Piwnica-Worms, H; Townsend, RR | 1 |
| Gurel, E; Mandaci, S; Ozturk, M; Watmough, NJ | 1 |
| Gruic-Sovulj, I; Rokov-Plavec, J; Weygand-Durasevic, I | 1 |
| Gnad, F; Kumar, C; Macek, B; Mann, M; Mijakovic, I; Olsen, JV; Soufi, B | 1 |
| Anumula, KR | 1 |
| Berthiaume, F; Campos, M; Charbonneau, ME; Dumas, F; Girard, V; Lépine, F; Mourez, M; Nikolakakis, A | 1 |
| Fan, Z; Ke, ZJ; Luo, J; Wang, B; Wang, X | 1 |
| Wang, Y; Zhang, Q | 1 |
| Ishizuka, M; Kasai, S; Nagata, Y; Nishimura, K; Ohnishi, M; Saito, M; Wakabayashi, S | 1 |
| Dive, C; Griffiths, JR; Welman, A; Whetton, AD | 1 |
| Ernst, JF; Lengeler, KB; Tielker, D | 1 |
| Campbell, DG; Chen, S; Mackintosh, C; Morrice, NA; Murphy, J; Toth, R | 1 |
| Hannun, YA; Jones, JA; Marchesini, N | 1 |
| Hashimoto, E; Ito, S; Li, Z; Sakamoto, Y; Sugimoto, I | 1 |
| Gargus, JJ; Tournay, A | 1 |
| Al-Younes, H; Braun, PR; Gussmann, J; Klein, J; Meyer, TF; Schneider, E | 1 |
| Broomhead, HE; Cao, L; Fountain, SJ; North, RA; Young, MT | 1 |
| Hagen, L; Hørning, O; Jensen, ON; Kavli, B; Krokan, HE; Liabakk, NB; Otterlei, M; Pena-Diaz, J; Slupphaug, G; Sousa, MM; Sundheim, O; Torseth, K | 1 |
| Chahdi, A; Sorokin, A | 1 |
| Chugh, J; Hosur, RV; Kumar, D | 1 |
| De Vries, GW; Qin, S | 1 |
| Dias, JA; Gutiérrez-Sagal, R; Jardón-Valadez, E; Pérez-Solis, MA; Piñeiro, A; Ulloa-Aguirre, A; Uribe, A; Zariñán, T | 1 |
| Cirelli, C; Faraguna, U; Pfister-Genskow, M; Tononi, G; Vyazovskiy, VV | 1 |
| Ares, IR; Botana, LM; Cagide, E; Louzao, MC; Vieytes, MR; Vilariño, N; Yasumoto, T | 1 |
| Flaveny, C; Kusnadi, A; Perdew, GH; Reen, RK | 1 |
| Adams, S; Byrne, KM; Caruccio, L; Lee-Stroka, H; Martin, J; Robbins, FM; Slezak, SL; Stroncek, DF | 1 |
| Cheung, SM; Duronio, V; Ma, K; Marshall, AJ | 1 |
| Berndt, MC; Fahmy, RG; Kavurma, MM; Khachigian, LM; Luo, X; Midgley, VC; Molloy, MP; Peden, R; Santiago, FS; Tan, NY | 1 |
| Amann, K; Becker, JU; Dotsch, J; Engers, R; Gueler, B; Looijenga, LH; Royer-Pokora, B; Schulz, W; Schumacher, V; Stoop, H | 1 |
| Balaj, PO; Correia, CF; Maitre, P; Ohanessian, G; Scuderi, D | 1 |
| Castañeda-Patlán, C; García, W; González-Aguilar, H; Lam, TT; Meléndez, L; Mendoza-Hernández, G; Robles-Flores, M | 1 |
| Abe, H; Chen, X; He, W; Huang, K; Kodama, H; Liu, G; Lu, J; Manabe, M | 1 |
| Adachi, J; Harayama, H; Miyake, M; Tate, S | 1 |
| Kohda, K; Ra, M; Samejima, K; Taguchi, R; Tsumoto, H | 1 |
| Franzmann, M; Knudsen, SK; Otzen, DE; Stensballe, A; Westergaard, UB | 1 |
| Clark, K; Figdor, CG; Lasonder, E; Middelbeek, J; Morrice, NA; van Leeuwen, FN | 1 |
| Kitchen, J; Saunders, RE; Warwicker, J | 1 |
| Doi, M; Inoue, S; Kinoshita, T; Matsumoto, M; Nakayama, KI; Shimazaki, K | 1 |
| Dolly, JO; Perez-Branguli, F; Raghunath, A; Smith, L | 1 |
| Behera, RK; Mazumdar, S | 1 |
| Chang, NS; Hong, Q; Hsu, LJ; Kuo, E; Lee, MH; Lin, SR; Lin, YS; Schultz, L | 1 |
| Bi, X; Chen, LM; Hew, CL; Wang, F | 1 |
| Arlinghaus, RB; Sun, T | 1 |
| Adamou, S; Adehossi, E; Duchemin, JB; Hassane, H; Ibrahim, ML; Jeanne, I; Konate, L; Ousmane, I | 1 |
| Siegel, JN | 1 |
| Field, RA; Kärkkäinen, TS; Macmillan, D; Ravindranathan Kartha, KP | 1 |
| Amano, T; Bekele, BN; Benedict, WF; Lang, FF; Liu, TJ; Nakamizo, A; Ramdas, L; Sasaki, T; Sawaya, R; Shono, T; Zhang, W; Zhang, XQ | 1 |
| Baliova, M; Franekova, V; Jursky, F | 1 |
| Frank, S; Goren, I; Müller, E; Pfeilschifter, J | 1 |
| Kluskens, LD; Kuipers, OP; Lubelski, J; Moll, GN; Overkamp, W | 1 |
| Helling, S; Kadenbach, B; Marcus, K; Ramzan, R; Rhiel, A; Vogt, S; Wen, L | 1 |
| Choi, S; Han, D; Kang, ES; Kim, Y; Kwak, TK; Lee, JW; Lee, SA; Oh, MA; Park, J; Park, ZY | 1 |
| Baldini, G; Bettati, S; Bosisio, C; Campanini, B; Chirico, G; Collini, M; D'Alfonso, L; Quercioli, V; Raboni, S | 1 |
| Bannai, M; Mori, M; Nagao, K; Seki, S; Takahashi, M | 1 |
| Dunlap, D; French, DM; Hotzel, K; Mohtashemi, I; Pai, R; Qing, J | 1 |
| Avila, RL; Flores, AI; Kidd, G; Kirschner, DA; Macklin, WB; Morse, EN; Narayanan, SP; Shick, HE; Yin, X | 1 |
| Haltiwanger, RS; Irvine, KD; Ishikawa, HO; Takeuchi, H | 1 |
| Armentrout, PB; Ye, SJ | 1 |
| Armentrout, PB; Clark, AA; Ye, SJ | 1 |
| Gnad, F; Jensen, PR; Macek, B; Mann, M; Mijakovic, I; Petranovic, D; Soufi, B | 1 |
| Appaji Rao, N; Bhavani, BS; Bisht, S; Kaul, P; Murthy, MR; Prakash, V; Rajaram, V; Savithri, HS | 1 |
| Diedrich, JK; Julian, RR | 1 |
| Kalkhof, S; Sinz, A | 1 |
| Härd, T; Syed, ZA; Uv, A; van Dijk-Härd, IF | 1 |
| Adeola, O; Asem, EK; Onyango, EM | 1 |
| Abrams, CS; Choi, SC; Khoo, C; Li, L; Lucast, L; Pan, W; Qin, Y; Sokol, SY; Swan, L; Volpicelli-Daley, L; Wang, H; Wu, D; Zhang, X | 1 |
| Raivich, G | 1 |
| Burack, WR; Iwanicki, MP; Kumar, D; Nandicoori, VK; Parsons, JT; Tiwari, D; Vomastek, T; Weber, MJ | 1 |
| Dagnino, L; Ivanova, IA; Nakrieko, KA | 1 |
| Guarna, A; Sladojevich, F; Trabocchi, A | 1 |
| Andreazza, HJ; Bilusich, D; Bowie, JH; Eichinger, PC; Fitzgerald, M; Hoffmann, P; Hoffmann, R | 1 |
| Agard, DA; Ho, BK | 1 |
| Katoh Hashimoto, Y; Nakae, J; Okamoto, M; Olson, EN; Takemori, H | 1 |
| Jiang, Y; Yu, Q; Zhang, N; Zhao, W; Zou, J | 1 |
| Björk, K; Hansson, AC; Heilig, M; Hyytiä, P; Neznanova, O; Rimondini, R; Sommer, WH | 1 |
| Krześlak, A | 1 |
| Hwang, CS; Varshavsky, A | 1 |
| Cho, M; Han, H; Joo, C; Kim, E; Lee, KK; Song, J | 1 |
| Blom, N; Jers, C; Macek, B; Mijakovic, I; Miller, ML; Soufi, B | 1 |
| Bekker, OB; Danilenko, VN; Elizarov, SM; Kubbutat, MH; Lakatosh, SA; Luzikov, YN; Preobrazhenskaya, MN; Printsevskaya, SS; Reznikova, MI; Schächtele, C; Shtil, AA; Simonov, AY; Totzke, F | 1 |
| Akhtar, J; Dattani, ID; Desai, KM; Gopalakrishnan, V; Mishra, RC; Quest, D; Tripathy, S | 1 |
| Cao, J; Chen, W; Dai, B; Lin, D; Liu, L; Liu, Y; Ma, D; Sun, Y; Yu, H | 1 |
| Chang, HI; Lim, K | 1 |
| Gauthier, MS; Gerhart-Hines, Z; Ido, Y; Kelly, M; Nelson, LE; Puigserver, P; Ruderman, NB; Saha, AK; Suchankova, G | 1 |
| Izumi, Y; Kamiya, M; Kretsinger, RH; Kumaki, Y; Matsushima, N; Tanaka, T; Yoshida, H | 1 |
| Cepeda, D; Klotz, K; Sangfelt, O; Spruck, C; Sun, D; Tan, Y | 1 |
| Abe, Y; Akao, T; Akiba, T; Harata, K; Higuchi, K; Ichimatsu, T; Ito, A; Kanai, R; Katayama, H; Kitada, S; Kusaka, Y; Mizuki, E; Ohba, M | 1 |
| Banker, P; Bickett, DM; Clancy, DC; Dickerson, SH; Garrido, DM; Golden, PL; Peat, AJ; Sheckler, LR; Sparks, SM; Tavares, FX; Thomson, SA; Weiel, JE | 1 |
| Aker, J; Boeren, S; de Vries, S; Karlova, R; Kwaaitaal, M; van Dongen, W; Vervoort, J | 1 |
| Chruszcz, M; Gluba, W; Koclega, KD; Maier, B; Minor, W; Sasaki, T; Scrable, H; Stukenberg, PT | 1 |
| Galocha, B; García-Medel, N; Gómez, P; López de Castro, JA; Mavian, C | 1 |
| Greene, LA; Jin, ZH; Malagelada, C | 1 |
| Amaral, AU; Beskow, AP; da Silva, Lde B; Fernandes, CG; Leipnitz, G; Seminotti, B; Wajner, M | 1 |
| Gao, Y; Liu, J; Longo, LD; Negash, S; Raj, JU | 1 |
| Chen, CJ; Li, C; Shively, JE | 1 |
| Attal, M; Bousquet, M; Chaussade, C; Cuzin, L; Demur, C; Dos Santos, C; Gallay, N; Payrastre, B; Récher, C; Simmonet Gouy, V | 1 |
| Dehlin, EM; Fang, H; Jhaveri, S; Kamatchi, GL; Oronce, CI; Rajagopal, S; Sando, JJ; Snyder, SL; Taneja, S | 1 |
| Becker, A; Funke, T; Han, H; Healy-Fried, M; Olesen, S; Schönbrunn, E; Yang, Y | 1 |
| Abbott, KL; Desjardins, A; Di Lello, P; Legault, P; Omichinski, JG; Yang, A | 1 |
| Appella, E; Bai, Y; Cherry, S; Durell, SR; Feng, H; Hayashi, R; Jenkins, LM; Mazur, SJ; Miller, M; Tropea, JE; Wlodawer, A | 1 |
| Frost, AL; Itzhaki, RF; Wozniak, MA | 1 |
| Beckhouse, AG; Chiu, J; Dawes, IW; Gelling, CL; Higgins, VJ; Lauterbach, L; Raftery, MJ; Rogers, PJ; Tsoi, AM; Tsoi, BM | 1 |
| Chan, GC; DiRocco, DP; Scheiner, ZS; Sindreu, CB; Storm, DR | 1 |
| Absalon, C; Delattre, D; Holland, IB; Madec, E; Obuchowski, M; Séror, SJ | 1 |
| Auff, E; Balzar, J; Brücke, T; Daniel, G; Edris, S; El Tawil, S; Foki, T; Gasser, T; Haubenberger, D; Katzenschlager, R; Lichtner, P; Pirker, W; Reinthaler, E; Schulte, C; Zimprich, A | 1 |
| Benlhabib, H; Liu, D; Mendelson, CR | 1 |
| Aivaliotis, M; Gnad, F; Macek, B; Mann, M; Oesterhelt, D; Reichelt, P | 1 |
| Ha, NC; Jung, J; Jung, Y; Lee, J; Lee, SJ; Oh, S; Park, BJ; Piao, S; Xu, Y; Yum, S | 1 |
| Higashimae, N; Hori, S; Kakizuka, A; Kato, N; Kimura, Y; Koike, M; Maeda, R; Mori-Konya, C; Noguchi, M; Ohizumi, H; Yasuda, K | 1 |
| Burness, K; Fuller, W; Hastie, CJ; Howie, J; McLatchie, LM; Pavlovic, D; Shattock, MJ; Weber, RJ | 1 |
| Oja, SS; Saransaari, P | 1 |
| Landry, CR; Levy, ED; Michnick, SW | 1 |
| Gehrig, PM; Reiland, S; Roschitzki, B; Rutishauser, D; Schlapbach, R | 1 |
| Feinmark, SJ; Guo, J; Harleton, E; Rybin, VO; Steinberg, SF | 1 |
| Drago, F; Frasca, A; Fumagalli, F; Pasini, M; Racagni, G; Riva, MA | 1 |
| Alessi, DR; García-Martínez, JM; Pearce, LR | 1 |
| Ishihama, Y; Ravichandran, A; Sugiyama, N; Swarup, S; Tomita, M | 1 |
| Cho, HS; Choi, HJ; Hyun, MH | 1 |
| Cho, N; Di Nardo, A; Kramvis, I; Kwiatkowski, DJ; Meikle, L; Sadowski, A; Sahin, M | 1 |
| Lommel, M; Strahl, S | 1 |
| Andreazza, HJ; Bilusich, D; Bowie, JH; Hoffmann, P; Wang, T | 1 |
| Minchin, RF; Mitchell, DJ | 1 |
| Reilly, JP; Zhang, L | 1 |
| Janssen, DB; Poelarends, GJ; Puthan Veetil, V; Quax, WJ; Raj, H | 1 |
| Rao, R | 1 |
| Goold, RG; Gordon-Weeks, PR; Kraus, M; Lin, S; Scales, TM | 1 |
| Ann, DK; Boo, LM; Chen, BP; Chen, DJ; Li, AY; Lin, HH; Wang, CC; Wang, SY; Yen, Y | 1 |
| Green, PL; Kesic, M; Semmes, OJ; Ward, M | 1 |
| Ashida, H; Fujita, K; Ozawa, H; Suzuki, S; Yamamoto, K | 1 |
| Kuhl, D; Lang, F; Schroth, J; Uchida, S; Vallon, V | 1 |
| Best, SM; Bhattacharya, D; Kuhn, RJ; Perera, R; Striker, R | 1 |
| Hayakawa, T; Ichijo, H; Iemura, S; Ishida, Y; Kinoshita, H; Komuro, Y; Murakami, S; Natsume, T; Noguchi, T; Oguchi, H; Sekine, Y; Takeda, K | 1 |
| Boosen, M; Illenberger, S; Kubicek, J; Preuss, U; Scheidtmann, KH; Vetterkind, S | 1 |
| van der Donk, WA; Zhang, X | 1 |
| Brustolon, F; Di Maira, G; Pinna, LA; Ruzzene, M | 1 |
| Bupha-Intr, T; Laosiripisan, J; Wattanapermpool, J | 1 |
| Kawanishi, M; Koizumi, K; Nishimura, M; Saiki, I; Sakurai, H; Shin, MS; Singhirunnusorn, P; Suzuki, S | 1 |
| Eng, JK; Han, DK; Hwang, SI; Lundgren, DH; Mayya, V; Rezaul, K; Rodionov, V; Wu, L | 1 |
| Huo, K; Shi, H; Shi, Y; Sun, Y; Wu, H; Ye, K | 1 |
| Bers, DM; Courtois, M; Desantiago, J; Flagg, TP; Kelly, DP; Kovacs, A; Leone, TC; Nichols, CG; Schaeffer, PJ; Weinheimer, CJ; Yang, J | 1 |
| Cimen, H; Koc, EC; Koc, H; Miller, JL | 1 |
| Feng, J; Kornbluth, S; Wakeman, T; Wang, XF; Wu, X; Yong, S | 1 |
| Chen, J; Du, GC; Gu, ZB; Li, ZF; Sun, Q; Wang, M; Wu, J; Zhang, JY | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Nemoto, S; Nogami, T; Taguchi, K | 1 |
| Chen, MM; Lee, CY; Leland, HA; Silletti, S | 1 |
| Albert, L; Gulati, N; Jhanwar-Uniyal, M; Karsy, M; Murali, R | 1 |
| Riemen, AJ; Waters, ML | 1 |
| Carr, AM; Miyabe, I; Morishita, T; Shinagawa, H | 1 |
| Campillo, M; Deupi, X; Dölker, N; Olivella, M; Pardo, L; Sanz, A | 1 |
| Collins, MO | 1 |
| Cidlowski, JA; Galliher-Beckley, AJ | 1 |
| Chen, SC; Hsu, WH; Lin, LL; Ong, PL | 1 |
| Hurt, MM; Rizkallah, R | 1 |
| Antonyan, A; Bloch, W; Brixius, K; Cox, CS; Fischer, JH; Fischer, UM; Klass, O; Mehlhorn, U; Stock, U | 1 |
| Askham, JM; Chambers, PA; Knowles, MA; Platt, F; Snowden, H; Taylor, CF | 1 |
| Jiang, P; Mu, Y; Wilmouth, RC; Wu, B | 1 |
| Gao, X; Patel, TB | 1 |
| Ricks, TK; Trejo, J | 1 |
| Frank, AT; Gaur, NK; Klotz, SA; Lipke, PN; Otoo, HN; Ramsook, CB; Rauceo, JM; Soybelman, G; Tan, C | 1 |
| Ito, G; Iwatsubo, T; Kamikawaji, S | 1 |
| Kangawa, K; Kojima, M | 1 |
| Knight, CA | 1 |
| Arellano-Plancarte, A; Catt, KJ; Hernandez-Aranda, J; Olivares-Reyes, JA | 1 |
| Aebersold, R; Ahrens, CH; Basler, K; Brunner, E; Gerrits, B; Gevaert, K; Goetze, S; Hafen, E; Laczko, E; Lange, V; Mohanty, S; Mosimann, C; Niederer, EM; Qeli, E; Roschitzki, B; Staes, A; Timmerman, E; Vandekerckhove, J | 1 |
| Grant, B; Khavrutskii, IV; McCammon, JA; Taylor, SS | 1 |
| Ayilavarapu, S; Hasturk, H; Ito, K; Iwata, T; Kantarci, A; Omori, K; Van Dyke, TE; Yagi, M | 1 |
| Kumar, N; Mohanty, D | 1 |
| Deng, KM; Lin, Q; Lu, Y; Niu, YY; Yao, LY; Zhang, JH | 1 |
| Avenoza, A; Busto, JH; Corzana, F; Fernández-Tejada, A; Peregrina, JM | 1 |
| Wu, XH; Wu, YD; Zhang, H | 1 |
| Ali, V; Husain, A; Jeelani, G; Nozaki, T; Sato, D | 1 |
| Chen, Y; Jiang, J; Li, S; Shi, Q; Wang, B; Yue, T; Zhang, Q | 1 |
| Donald, AS | 1 |
| Ahabrach, H; Boix, J; ElMlili, N; Errami, M; Felipo, V; Rodrigo, R | 1 |
| Abe, H; Chi, H; He, W; Kitaoka, N; Kodama, H; Liu, G; Yamashita, K | 1 |
| Carvalheira, JB; Carvalho, HF; Clemente, CF; Dalla Costa, AP; Franchini, KG; Nadruz, W | 1 |
| Bourron, O; Daval, M; Ferré, P; Foufelle, F; Gautier, JF; Hainault, I; Hajduch, E; Servant, JM | 1 |
| Borrelli, E; Kinoshita, C; Sahar, S; Sassone-Corsi, P; Zocchi, L | 1 |
| Barona-Gómez, F; Camacho-Zarco, AR; Fülöp, V; Noda-García, L; Soberón, X; Verdel-Aranda, K; Wright, H | 1 |
| Chang, HP; Hsueh, YP; Huang, TN | 1 |
| Burlingame, S; Fu, S; Ge, N; Li, X; Sun, W; Yang, J; Ye, S; Yu, Y; Zhang, M | 1 |
| Grammenoudi, S; Kosmidis, S; Papanikolopoulou, K; Skoulakis, EM | 1 |
| Anderson, RE; Kanan, Y; Matsumoto, H; Rajala, RV; Sokolov, M; Song, H | 1 |
| Alexander, JK; Baker, LK; Bubula, N; Carlezon, WA; Inamine, H; Loweth, JA; Neve, RL; Singer, BF; Vezina, P; Wilke, G | 1 |
| Flynn, NE; Patyrak, ME; Seely, JB; Wu, G | 1 |
| Becher, D; Gronau, K; Hecker, M; Pietack, N; Schmidl, SR; Stülke, J | 1 |
| Chandrasekaran, S; Mishra, R; Ramapanicker, R | 1 |
| Barbiroli, A; Bernini, F; Bonomi, F; Calabresi, L; Favari, E; Franceschini, G; Gomaraschi, M; Iametti, S; Pozzi, S; Putt, WE; Talmud, PJ | 1 |
| Enari, M; Hirota, T; Kodama, M; Otsubo, C; Taya, Y; Yokota, J | 1 |
| Fujii, H; Hattori, Y; Hayashi, T; Matsuda, N; Nishioka, H; Yokoo, H; Zhang, XH | 1 |
| Diamant, M; Guigas, B; Jazet, IM; Kriek, J; Maassen, JA; Nascimento, EB; Ouwens, DM; Snel, M; van der Zon, GC | 1 |
| Asara, JM; Gwinn, DM; Shaw, RJ | 1 |
| Ikeda, T; Matsushima, O; Naono, R; Nishimori, T; Sakoda, S; Sunakawa, N | 1 |
| Bolling, A; Ingvaldsen, A; Jensen, J; Kolnes, AJ; Kreft, M; Shepherd, PR; Stuenaes, JT; Zorec, R | 1 |
| Armentrout, PB; Bowman, VN; Heaton, AL | 1 |
| Bardou, F; Boudou, F; Brodin, P; Burlet-Schiltz, O; Darthuy, E; Gicquel, B; Gilleron, M; Jang, J; Levillain, F; Monsarrat, B; Neyrolles, O; Puzo, G; Stella, A; Vaubourgeix, J; Wang, C | 1 |
| Calbet, JA; Fuentes, T; Guadalupe-Grau, A; Guerra, B; Guillén-Salgado, J; Morales-Alamo, D; Olmedillas, H; Ponce-González, JG; Santana, A | 1 |
| Jung, SY; Kuang, J; Li, W; Liang, J; Liang, Q; Lin, SH; Qin, J; Wang, R; Wu, CF | 1 |
| Bradley, EA; Clark, MG; Eringa, EC; Korstjens, I; Musters, R; Rattigan, S; Sipkema, P; Stehouwer, CD; van Nieuw Amerongen, GP | 1 |
| Jamieson, AG; Lubell, WD; St-Cyr, DJ | 1 |
| Chan, CK; Lam, HY; Li, X; Zhang, Y | 1 |
| Kingsbury, JM; McCusker, JH | 1 |
| Ausió, J; Ishibashi, T; Lee, SC; Lees-Miller, SP; Li, A; Yu, Y | 1 |
| Avila, J; Cheng, C; Devarenne, TP; Ek-Ramos, MJ; Martin, GB | 1 |
| Becher, D; Commichau, FM; Hecker, M; Pietack, N; Saier, MH; Schmidl, SR; Stülke, J | 1 |
| Hosoi, F; Izumi, H; Kohno, K; Kuwano, M; Maruyama, Y; Murakami, Y; Ono, M; Ureshino, H; Watari, K | 1 |
| Dreyer, I; Gambale, F; Sato, A; Uozumi, N | 1 |
| Elks, CM; Francis, J | 1 |
| Fan, Y; Fu, S; Lu, X; Sun, W; Wang, H; Wang, X; Yang, J; Yu, Y; Zhang, G; Zhao, X | 1 |
| Francklyn, CS; Minajigi, A | 1 |
| Anthonsen, MW; Bergstroem, B; Hagen, L; Johnsen, IB; Nguyen, TT; Slupphaug, G; Thommesen, L | 1 |
| Allan, LA; Clarke, PR; Harley, ME; Sanderson, HS | 1 |
| Dochi, T; Hasegawa, N; Inoue, M; Kishimoto, N; Misumi, S; Shoji, S; Takamune, N | 1 |
| Ehara, T; Itano, N; Sugaya, A; Taguchi, A; Takeoka, M; Taniguchi, S | 1 |
| Baker, P; Burlingame, AL; Chalkley, RJ; Darula, Z; Medzihradszky, KF | 1 |
| Arts, A; Bontemps, F; Ntamashimikiro, S; Smal, C; Van Den Neste, E | 1 |
| Biswas, R; Bloch, RJ; Shenolikar, S; Steplock, D; Weinman, EJ; Zhang, Y | 1 |
| Annamalai, B; Arapulisamy, O; Jayanthi, LD; Mannangatti, P; Ramamoorthy, S | 1 |
| Dangelmaier, CA; Daniel, JL; Getz, TM; Jin, J; Kunapuli, SP | 1 |
| Brunner, T; Espinosa, J; Fiedler, N; Forchhammer, K; Maldener, I; Muro-Pastor, AM | 1 |
| De Leo, L; Di Toro, N; Fasano, A; Goldblum, SE; Hollenberg, MD; Not, T; Puche, AC; Rai, U; Ramachandran, R; Thakar, M; Tripathi, A | 1 |
| Kaneko, Y; Kondo, H; Tamura, K; Totsukawa, G | 1 |
| Guy, GR; Jackson, RA; Ng, C; Sivaraman, J; Sun, Q | 1 |
| McAvoy, T; Nairn, AC | 1 |
| Honda, T; Tanno, Y; Watanabe, Y; Yamagishi, Y | 1 |
| Ding, G; Geistlinger, L; Li, H; Li, Y; Liu, L; Tateno, Y; Wang, Z; Zeng, R | 1 |
| Azad, A; Edelmann, MJ; Fox, JL; Ismail, F; Jackson, S; Kessler, BM; Leigh, IM; Leverrier, S; Storey, A; Ternette, N | 1 |
| Barbeito, P; Covelo, G; Díaz-Jullien, C; Freire, M; Moreira, D; Sarandeses, CS | 1 |
| Guatelli, JC; Munguia, J; Tokarev, AA | 1 |
| Chica, C; Diella, F; Dinkel, H; Gibson, TJ; Gould, CM; Jensen, LJ; Via, A | 1 |
| Gu, J; Liu, Y; Ren, H; Sun, Z; Teeling, JL | 1 |
| Han, Y; Song, P; Wang, Q; Zhu, Y; Zou, MH | 1 |
| Carman, GM; Choi, HS; Han, GS; Karanasios, E; Morgan, JM; Siniossoglou, S; Su, WM; Xu, Z | 1 |
| Hendershot, LM; Okuda-Shimizu, Y; Shimizu, Y | 1 |
| Avenoza, A; Busto, JH; Corzana, F; Davis, AP; Fernández-Tejada, A; Jiménez-Barbero, J; Joshi, G; Peregrina, JM | 1 |
| Bertelsen, S; Chiang, HH; Cruchaga, C; Goate, A; Graff, C; Hinrichs, AL; Mayo, K; Morris, JC; Norton, JB; Spiegel, N; Wang, J | 1 |
| Arzeno, J; Bellovin, DI; Cao, Z; Fan-Minogue, H; Felsher, DW; Gambhir, SS; Yang, Q; Yevtodiyenko, A | 1 |
| Fujitani, N; Gao, XD; Hashimoto, R; Hinou, H; Kaneko, A; Kurogochi, M; Manri, N; Matsushita, T; Naruchi, K; Nishimura, S; Ohyabu, N; Sakamoto, T; Satake, H; Takegawa, Y | 1 |
| Gray, VE; Kumar, S | 1 |
| Chikamori, K; Ganapathi, MK; Ganapathi, R; Grozav, AG; Kinter, M; Kozuki, T; Micluta, MA; Petrescu, AJ; Willard, BB | 1 |
| Chen, J; Chen, K; Liu, J; Liu, L; Zhang, J; Zhou, J | 1 |
| Ballard, JD; Bryant-Hudson, KM; Shakir, SM | 1 |
| Alessi, DR; Campbell, DG; de los Heros, P; Deak, M; Prescott, AR; Richardson, C; Sakamoto, K | 1 |
| Adi, J; Adi, N; Chopra, I; Dougherty, CJ; Li, HF; Wang, H; Wang, W; Webster, KA; Wei, J | 1 |
| Barndt, RJ; Cheema, AK; Coticchia, CM; Deb, TB; Johnson, MD; Sengupta, S; Wang, Y; Zuo, AH | 1 |
| Bernardo, M; Chiang, J; Lonser, R; Lu, J; Martiniova, L; Pacak, K; Zhuang, Z | 1 |
| Liu, J; Liu, Q; Liu, S; Shen, Y; Weng, J | 1 |
| Bächinger, HP; Masakiyo, K; Miyama, K; Mizuno, K; Morimoto, T; Okuyama, K | 1 |
| Burton, GJ; Charnock-Jones, DS; Yung, HW | 1 |
| Liu, X; Nobumori, Y; Panowicz, MJ; Shouse, GP | 1 |
| Al-Eryani, R; Ball, HL; Li, Y; Orth, K; Yarbrough, ML | 1 |
| Endo, Y; Nemoto, K; Nozawa, A; Sawasaki, T; Seki, M; Seto, T; Shinozaki, K; Takahashi, H | 1 |
| Belke, DD | 1 |
| Elder, DJ; Hetzel, MR; May, MT; Morgan, C; Pawade, J; Phillips, L; Sohail, M; Tavaré, JM; Thomas, EC; Vincent, EE | 1 |
| Brandt, Y; Hartley, RS; Mitchell, T; Wu, Y | 1 |
| Brown, A; DiSanto-Rose, M; Gaugler, M; Merrell, E; Rathmacher, JA; Reynolds, TH | 1 |
| Buxton, RS; Leiba, J; Molle, V; Rodgers, A; Smerdon, SJ; Spivey, VL; Stach, L; Walker, KB; Whalan, RH | 1 |
| Black, SM; Darragh, C; Elms, S; Fonseca, FV; Fulton, D; Kumar, S; Pardo, D; Rafikov, R | 1 |
| Samelson, BK; Scott, JD; Smith, FD | 1 |
| Chen, GR; Chen, K; Deng, Q; Gao, LX; He, XP; Li, C; Li, J; Shi, XX; Tang, Y; Xie, J; Zhang, W; Zhou, YB | 1 |
| Alioua, A; Li, M; Stefani, E; Toro, L; Wu, Y | 1 |
| Blennow, K; Brinkmalm, G; Halim, A; Larson, G; Nilsson, J; Portelius, E; Rüetschi, U; Westman-Brinkmalm, A; Zetterberg, H | 1 |
| Chao, Y; Lan, KH; Lee, SD; Lee, WP; Li, CP; Lin, HC; Su, CH; Wang, CY | 1 |
| Ahmed, AA; Bast, RC; Claret, FX; He, G; Hung, MC; Le, XF; Mao, W; Siddik, ZH; Xia, W | 1 |
| Daffé, M; Eynard, N; Kremer, L; Leiba, J; Molle, V; Quémard, A; Slama, N | 1 |
| Adenier, A; Ghomi, M; Hernández, B; Kruglik, SG; Nsangou, M; Pflüger, F | 1 |
| Hasegawa, M; Kishino, H; Kitazoe, Y; Lane, N; Matsui, A; Tanaka, M | 1 |
| Bae, SJ; Cho, JW; Choi, SR; Gwak, J; Ha, NC; Han, JK; Hwang, SG; Kim, DE; Kim, H; Oh, S; Park, HS; Park, SH | 1 |
| Henderson, JM; Kraus, M; Otipoby, KL; Patterson, HC; Rajewsky, K; Seagal, J; Shahsafaei, A; Thai, TH; Wang, D | 1 |
| De Filippis, E; Finlayson, J; Langlais, P; Luo, M; Mandarino, LJ; Mapes, R; Mattern, M; Meyer, C; Plummer, E; Tongchinsub, P; Yi, Z | 1 |
| Dong, MQ; Han, Y; Hou, W; Jing, Z; Li, J; Liao, J; Tian, C; Wang, J; Xu, X | 1 |
| Ackermann, MA; Kontrogianni-Konstantopoulos, A | 1 |
| Chen, XP; Cui, L; Hoi, PM; Tan, W; Wang, YT; Wu, GS; Wu, T; Xu, ZT; Zhong, ZF | 1 |
| Chou, KC; He, ZS; Kong, XY; Shi, XH; Zhu, YB | 1 |
| Gallo-Payet, N; Parent, JL; Pinard, S; Rached, M; Roy, S; Roy, SJ; Taillefer, LD | 1 |
| Combs, B; Gamblin, TC; Voss, K | 1 |
| Bouchoux, G; Frison, G; Riffet, V | 1 |
| Kay, EP; Lee, JG; Smith, RE; Song, JS | 1 |
| Jee, J; Kainosho, M; Ono, AM; Takeda, M; Terauchi, T | 1 |
| Aké, F; Deutscher, J; Henry, C; Mijakovic, I; Milohanic, E; Misra, SK; Monnet, V | 1 |
| Liang, B; Shirwany, N; Wang, Q; Zhang, M; Zhu, Y; Zou, MH | 1 |
| Cho, M; Han, H; Hwang, GS; Jung, Y; Kim, SY | 1 |
| Araki, K; Fujitani, N; Furukawa, J; Kodama, K; Shinohara, Y; Takegawa, Y | 1 |
| Jensen, ON; Manteca, A; Sánchez, J; Ye, J | 1 |
| Bartke, A; Díaz, ME; González, L; Martínez, CS; Miquet, JG; Sotelo, AI; Turyn, D | 1 |
| Biarc, J; Bradshaw, RA; Burlingame, AL; Chalkley, RJ | 1 |
| Albers, MF; Hedberg, C; van Vliet, B | 1 |
| Csaderova, L; Dequiedt, F; Ditte, P; Hulikova, A; Kopacek, J; Ohradanova-Repic, A; Pastorek, J; Pastorekova, S; Supuran, CT; Svastova, E; Zatovicova, M | 1 |
| Bayraktar, R; Cengiz, B; Cetin, GY; Demiryurek, AT; Donmez, S; Gogebakan, B; Kisacik, B; Koca, SS; Onat, AM; Ozgen, M; Oztuzcu, S; Pehlivan, Y; Sayarlioglu, M | 1 |
| Harrison, AG | 1 |
| Akal-Strader, A; Becker, JM; Hauser, M; Kim, KM; Lee, YH; Naider, F; Uddin, MS | 1 |
| Beach, JR; Crish, JF; Egelhoff, TT; Licate, LS | 1 |
| Albert, PR; Dehpour, AR; Ghahremani, MH; Ghazi-Khansari, M; Ostad, SN; Rahimian, R; Seyedabadi, M | 1 |
| Baulac, S; Ishida, S; Kaneko, S; Kuwamura, M; Mashimo, T; Nishio, T; Ohno, Y; Sakamoto, Y; Serikawa, T; Takizawa, A | 1 |
| Herinckx, G; Hussain, N; Proud, CG; Pyr Dit Ruys, S; Rider, MH; Smith, EM; Vertommen, D; Wang, X | 1 |
| Egawa, T; Hayashi, T; Kurogi, E; Ma, X; Oshima, R; Tsuda, S | 1 |
| Chen, JH; Huang, ZR; Liu, HY; Zhu, SJ | 1 |
| Kim, H; Kim, YU; Nakajima, C; Suzuki, Y; Yokoyama, K | 1 |
| Andersen, B; Beck-Nielsen, H; Birk, JB; Højlund, K; Vienberg, SG; Vind, BF; Wojtaszewski, JF | 1 |
| Abramczyk, O; Brodbelt, JS; Dalby, KN; Devkota, AK; Ferguson, SB; Kaoud, TS; Keller, KM; Marshall, KD; O'Brien, JP; Ozpolat, B; Shores, KS; Tavares, CD; Warthaka, M; Zhang, Y | 1 |
| English, RD; Kurosky, A; Wiktorowicz, JE; Wu, Z | 1 |
| Jayabaskaran, C; Srideshikan, SM; Vanishree, VL | 1 |
| Bartlett, RK; Baucum, AJ; Colbran, RJ; Jalan-Sakrikar, N | 1 |
| Armentrout, PB; Chen, Y; Rodgers, MT | 1 |
| Brumbaugh, J; Coon, JJ; Hou, Z; Howden, SE; Ledvina, AR; Russell, JD; Thomson, JA; Yu, P | 1 |
| Boyko, W; Cummings, C; Giuliano, R; Hughes, K; Johnson, D; Licisyn, T; Scholl, C | 1 |
| Huang, Q; Lai, B; Li, M; Liu, S; Ma, S; Song, B; Wang, C; Xie, B | 1 |
| Gao, G; Guo, X; Lv, F; Sun, L | 1 |
| Brautigan, DL | 1 |
| Compton, DA; Gerber, SA; Hood, EA; Kettenbach, AN | 1 |
| Baldini, G; Granell, S; McDaniel, FK; McPike, L; Mohammad, S; Molden, BM; Narducci, P | 1 |
| Abe, H; Nakanishi, S; Okazawa, M | 1 |
| Burke, LM; Coffey, VG; Garnham, AP; Hawley, JA; Moore, DR; Phillips, SM; Ross, ML; Slater, GR; Stellingwerff, T; Tipton, KD | 1 |
| Edimo, WE; Erneux, C; Janssens, V; Waelkens, E | 1 |
| Blough, ER; Kakarla, SK; Katta, A; Kolli, MB; Kundla, S; Manne, ND; Nalabotu, SK; Wu, M | 1 |
| Gholami, AM; Hahne, H; Kuster, B | 1 |
| Berciano, J; Infante, J; Pelayo-Negro, AL; Rodríguez-Oroz, MC; Sánchez-Quintana, C; Tola-Arribas, MA; Volpini, V; Zeviani, M | 1 |
| Deason-Towne, F; Perraud, AL; Schmitz, C | 1 |
| Anjak, A; Cai, WF; Figueria, S; Florea, S; Haghighi, K; Kranias, EG; Lorenz, J; Qian, J; Rubinstein, J; Vafiadaki, E | 1 |
| Hsiang, TY; Krug, RM; Zhou, L | 1 |
| Mui, AL; So, EY | 1 |
| Allis, CD; Elsässer, SJ; Fischle, W; Klingberg, R; Liokatis, S; Schwarzer, D; Selenko, P; Stützer, A; Theillet, FX; van Rossum, B | 1 |
| Chakraborty, S; Hosur, RV; Susmitha, AL | 1 |
| Erdődi, F; Kőszeghy, Á; Lontay, B; Pál, B; Rusznák, Z; Serfőző, Z; Szücs, G | 1 |
| Barchi, JJ; Gildersleeve, JC; Muthana, SM; Zhang, Y | 1 |
| Bondar, AN; Del Val, C; White, SH | 1 |
| Copps, KD; White, MF | 1 |
| Bakó, É; Bécsi, B; Czikora, Á; Erdődi, F; Gergely, P; Kiss, A; Kolozsvári, B; Tóth, A; Vámosi, G | 1 |
| Cichutek, K; Flory, E; Jaguva Vasudevan, AA; Kopietz, F; Krämer, M; Muckenfuss, H; Münk, C; Sanzenbacher, R | 1 |
| Christopherson, MR; Downs, D; Downs, DM; Lambrecht, JA | 1 |
| Doucette, CD; Hilchie, AL; Hoskin, DW; Liwski, R | 1 |
| Arias, EB; Cartee, GD; Schweitzer, GG | 1 |
| Boos, I; Freund, J; Pöhner, C; Rädisch, M; Schwarzinger, S; Ullmann, V; Unverzagt, C | 1 |
| de Giuseppe, PO; dos Santos, CR; Martins, NH; Meza, AN; Murakami, MT; Pereira, HD | 1 |
| Feig, M; Sayadi, M | 1 |
| Draber, P; Helm, BA; Housden, JE; Rashid, A | 1 |
| Jeong, JK; Lee, JH; Lee, YJ; Moon, MH; Park, SY; Park, YG; Seol, JW | 1 |
| Brito, N; González, C; González, M | 1 |
| Kosten, J; Kriwacki, RW; Landrieu, I; Liokatis, S; Lippens, G; Selenko, P; Smet-Nocca, C; Theillet, FX; Thongwichian, R; Yoon, MK | 1 |
| Blasic, JR; Brown, RL; Robinson, PR | 1 |
| Katritzky, AR; Monbaliu, JC | 1 |
| Clouse, SD; Harper, JF; Huber, SC; Kim, HS; Oh, MH; Wu, X; Zielinski, RE | 1 |
| Cho, DI; Choi, HK; Kim, KM; Kwon, KJ; Min, C; Shin, CY; Zheng, M | 1 |
| He, P; Wang, M; Yuan, D; Zhou, X | 1 |
| Huang, Q; Ruan, ZR; Tan, M; Wang, ED; Zhou, XL | 1 |
| Aschi, M; Bozzi, A; Daidone, I; Patamia, M; Petruzzelli, R | 1 |
| Glass, B; Kräusslich, HG; Morales, I; Müller, B; Radau, S; Radestock, B; Rahman, SA; Zahedi, RP | 1 |
| Rehse, PH; Song, Y; Yin, Z | 1 |
| Hunt, DF; Jahren, N; Kim, YC; Markowski, TW; Olszewski, NE; Shabanowitz, J; Stone, MD; Udeshi, ND; Witthuhn, BA | 1 |
| Kidokoro, S; Kusakabe, K; Maruyama, K; Mizoi, J; Moriwaki, T; Ohori, T; Osakabe, Y; Shinozaki, K; Todaka, D; Yamaguchi-Shinozaki, K | 1 |
| Bertuch, AA; Chang, K; Cheung, HC; Hicks, S; Ribes-Zamora, A; San Lucas, FA | 1 |
| Cohen-Gonsaud, M; Corrales, RM; Kremer, L; Leiba, J; Molle, V | 1 |
| Carter, JH; Chi, Y; Clurman, BE; Hizli, AA; Liao, Y; Ryazanov, AG; Swanger, J; Welcker, M | 1 |
| Benda, L; Boelens, R; Emmer, J; Koča, J; Kříž, Z; Sklenář, V; Sychrovský, V; Trantírek, L; Vavrinská, A | 1 |
| Christ, F; De Rijck, J; Debyser, Z; Demeulemeester, J; Gérard, M; Gijsbers, R; Schrijvers, R | 1 |
| Cid, VJ; Gil, C; Hansen, R; Hernáez, ML; Jiménez-Sánchez, M; Martín, H; Mascaraque, V; Molina, M | 1 |
| Halim, A; Larson, G; Nilsson, J; Rüetschi, U | 1 |
| Burlingame, AL; Doll, C; Illing, S; Just, S; Kotowski, SJ; Lau, EK; Mann, A; Miess, E; Schulz, S; Trester-Zedlitz, M; Trinidad, JC; von Zastrow, M | 1 |
| Chen, Y; Dai, L; Kwon, OK; Lee, S; Tan, M; Yang, JS; Zhao, Y | 1 |
| Bansal, N; Berezney, R; Bhaskar, A; Fritz, A; Itotia, P; Lam, TT; Lee, E; Lyubchenko, YL; Shlyakhtenko, LS; Stafford, WF; Thapar, R; Zhang, M | 1 |
| Gangopadhyay, SS; Grabarek, Z; Leavis, P; Morgan, KG; Yilmaz, M | 1 |
| Cao, X; Li, N; Li, Y; Liu, X; Meng, J; Zhan, Z; Zhang, P; Zhu, X | 1 |
| Chatterjee, A; Dave, N; Govindappa, N; Hanumanthappa, M; Hazra, P; Kanojia, K; Kusumanchi, M; Sastry, K; Tiwari, S; Venkatarangaiah, K; Venkatesan, K | 1 |
| Hackeng, T; Ippel, H; Kumar, N; Mayo, KH; Weber, C | 1 |
| Balakrishnan, M; Chinnathambi, V; Ramadoss, J; Sathishkumar, K; Yallampalli, C | 1 |
| Chadee, AB; Chen, CY; Huang, KL; Shyu, AB; Zhang, Y | 1 |
| Afonin, S; Komarov, IV; Kubyshkin, VS; Mykhailiuk, PK; Radchenko, DS; Tkachenko, AN; Ulrich, AS | 1 |
| Albers, MF; Hedberg, C | 1 |
| Dhaksnamoorthy, R; Gabriel, N; Gadkari, RA; Hareendran, S; Hussain, M; Jayandharan, GR; Samuel, R; Selot, R; Sen, D; Srinivasan, N; Srivastava, A; Sudha, G | 1 |
| Abrahams, CL; Baljinnyam, B; Brown, AM; González-Sancho, JM; Greer, YE; Lee, KH; Lee, KS; Rubin, JS; Takigawa, Y | 1 |
| Annesi, G; Cestèle, S; Franceschetti, S; Gambardella, A; Labate, A; Mantegazza, M; Mumoli, L; Rusconi, R; Tarantino, P | 1 |
| Baaden, M; Corringer, PJ; Delarue, M; Koehl, P; Malherbe, L; Moraga-Cid, G; Murail, S; Poitevin, F; Sauguet, L; Thompson, AW; Van Renterghem, C | 1 |
| Bustos, DM; Uhart, M | 1 |
| Allemann, RK; Chen, XY; Fang, X; Faraldos, JA; Li, JX; Miller, DJ; Ruan, JX; Wang, LJ; Yang, CQ; Zhang, P; Zhao, Q | 1 |
| Gabriel, N; Gadkari, RA; Jayandharan, GR; Kumar, YS; Nair, SC; Rajalingam, S; Ramya, V; Samuel, R; Selot, R; Sen, D; Srinivasan, N; Srivastava, A; Sudha, G | 1 |
| Ge, F; Li, T; Qiao, ZX; Xiong, Q; Yang, MK; Zhang, J; Zhang, WY; Zhao, JD | 1 |
| Blough, ER; Kakarla, SK; Kohama, K; Kohama, T; Nakamura, A; Nasu-Kawaharada, R | 1 |
| Bent, AF; Botting, CH; Fuszard, MA; Houssen, WE; Jaspars, M; Koehnke, J; Morawitz, F; Naismith, JH; Shirran, SL; Smellie, IA; Smith, MC | 1 |
| Kondo, H; Kubota, A; Matsuo, A; Taguchi, Y; Totsukawa, G | 1 |
| Cao, Y; Du, J; Fu, L; Huang, X; Wang, L; Xu, J; Zhang, A; Zhang, Z; Zheng, Q | 1 |
| Lam, HY; Li, X; Liu, H; Wong, CT; Xu, C; Xu, J; Zhang, Y | 1 |
| Lam, HY; Lee, CL; Li, X; Xu, C; Zhang, Y | 1 |
| Brown, JC; Chung, DJ; Hüner, NP; Staples, JF; Szyszka, B | 1 |
| Elkins, JM; Eswaran, J; Filippakopoulos, P; Gerber, SA; Kettenbach, AN; Knapp, S; Olsen, JV; Roos, AK; Savitsky, P; Soundararajan, M | 1 |
| Agrawal, P; Balakrishnan, B; Gabriel, N; Jayandharan, GR; Roshini, V; Samuel, R; Sen, D; Srivastava, A | 1 |
| Jefferson, LS; Kazi, AA; Kimball, SR; Tuckow, AP | 1 |
| Bonneau, R; Craven, TW; Kirshenbaum, K; Levine, PM | 1 |
| Bairagya, HR; Banerjee, A; Mishra, DK; Mukhopadhyay, BP; Nandi, TK | 1 |
| Furlan, AC; Moreira, I; Murakami, AE; Ospina-Rojas, IC; Picoli, KP; Rodrigueiro, RJ | 1 |
| Magness, RR; Pastore, MB; Ramadoss, J | 1 |
| D'Aquino, K; Feener, EP; King, GL; Li, Q; Maeda, Y; Mima, A; Mizutani, K; Park, K; Rask-Madsen, C; White, MF; Winnay, J | 1 |
| Collier, DN; Consitt, LA; Dar, MS; Houmard, JA; Newton, CA; Tanner, CJ; Treebak, JT; Van Meter, J; Wojtaszewski, JF | 1 |
| Binolfi, A; Liokatis, S; Rose, HM; Selenko, P; Stuiver, M; Theillet, FX; Thongwichian, R | 1 |
| Bamberg-Lemper, S; Becker, W; Birner-Gruenberger, R; Bracher, F; Hilz, N; Preisinger, C; Rüben, K; Walte, A | 1 |
| Katchman, A; Marx, SO; Morrow, J; Samad, T; Weinberg, R; Yang, L | 1 |
| Hishioka, N; Hosokawa, T; Kihara, Y; Kurasaki, M; Miyajima, M; Nishimura, R; Saito, T; Tanaka, M; Tanaka, S | 1 |
| Fang, S; Huang, M; Liu, DX; Qisheng Li, F; Xu, L | 1 |
| Bischof, J; Henne-Bruns, D; Knippschild, U; Pinna, LA; Randoll, SJ; Süßner, N | 1 |
| Rempe, SB; Rossi, M; Tkatchenko, A; Varma, S | 1 |
| Agalarov, Y; Delorenzi, M; Houhou, N; Ivanov, KI; Jaquet, M; Liebl, J; Maby-El Hajjami, H; Miura, N; Norrmén, C; Petrova, TV; Samuilova, O; Valmu, L; Ylä-Herttuala, S; Zangger, N | 1 |
| Li, T; Li, X; Zhang, Y | 1 |
| Dai, C; Liu, HT; Tan, ST; Xue, HW | 1 |
| Burlingame, AL; Chalkley, RJ; Guan, S; Maltby, DA; Ni, W; Pham, TN; Quail, PH; Wang, ZY; Xu, SL | 1 |
| Asif, AR; Herlyn, H; Ramljak, S; Schaffrath, M; Schumacher, J; Zischler, H | 1 |
| Häussinger, D; Kluge, S; Kubitz, R; Stross, C; Weissenberger, K; Winands, E | 1 |
| Grote, CW; Ryals, JM; Wright, DE | 1 |
| Dadheech, S; Hussien, MD; Jain, S; Jyothy, A; Munshi, A; Rao, AV; Shaheen, U | 1 |
| van der Donk, WA; Yu, Y; Zhang, Q | 1 |
| Bartels, JP; Huber, A; Oberegelsbacher, C; Pfannstiel, J; Voolstra, O | 1 |
| Khusainov, R; Kuipers, OP | 1 |
| Chen, Y; Choi, BH; Dai, W | 1 |
| Jia, CZ; Liu, T; Wang, ZP | 1 |
| Al-Zahrani, A; Arrigoni, G; Cant, N; Cozza, G; Ford, RC; Franchin, C; Mehta, A; Pagano, MA; Pinna, LA; Tosoni, K; Venerando, A | 1 |
| Daubenspeck, JM; Dybvig, K; Jordan, DS; Laube, AH; Renfrow, MB | 1 |
| Lyons, B; Schey, KL; Truscott, RJ; Wang, Z | 1 |
| Gopalakrishnan, V; Li, S; Liu, CC; Poon, LF; Yan, T | 1 |
| Kanno, T; Nishizaki, T; Tsuchiya, A | 2 |
| Amado, T; Bento, I; Bettencourt-Dias, M; Borrego-Pinto, J; Brito, D; Cunha-Ferreira, I; Debski, J; Duarte, P; Dzhindzhev, N; Gilberto, S; Jana, SC; Lince-Faria, M; Pimenta-Marques, A; Rodrigues-Martins, A | 1 |
| Lam, HY; Li, X; Tung, CL; Xu, J | 1 |
| Eidne, KA; Jaeger, WC; Pfleger, KD; Seeber, RM | 1 |
| Barauna, VG; Campos, LC; Krieger, JE; Magalhães, FC; Mantuan, PR | 1 |
| Brockerman, JA; McIntosh, LP; Okon, M | 1 |
| Al-Hassi, HO; Arranz, E; Bernardo, D; English, NR; Fernandez-Salazar, L; Garrote, JA; Hart, AL; Knight, SC; Landy, J; Lee, GH; Man, R; Mann, ER; Margolles, A; Peake, ST; Sanchez, B; Stagg, AJ; Urdaci, M | 1 |
| Bray, P; Dangelmaier, C; Jin, J; Kunapuli, SP; Liverani, E; Manne, BK | 1 |
| Gao, L; Huang, XP; Liu, R; Matsunaga, F; Roth, BL; Saven, JG | 1 |
| He, KL; He, YY; Li, RJ; Li, X; Liu, CL; Wang, LL | 1 |
| Brown, LA; Fitzpatrick, AM; Jones, DP; Park, Y | 2 |
| Anderson, LN; Grundner, C; Liao, R; Ollodart, AR; Ortega, C; Rustad, T; Sherman, DR; Wright, AT | 1 |
| Fernström, A; Frånlund, E; Magnusson, P; Osman, A; Uhlin, F | 1 |
| Burns, RN; Moniri, NH; Senatorov, IS; Singh, M | 1 |
| Gao, J; Ji, L; Jiang, X; Li, W; Luo, J; Qi, M; Wang, W; Xu, M; Yang, C; Yin, H; Zhang, D | 1 |
| Bachman, J; Huganir, RL; Jenkins, A; Jenkins, MA; Oswald, RE; Snyder, JP; Traynelis, SF; Wells, G | 1 |
| Bayliss, R; Bojar, D; Hothorn, M; Martinez, J; Rybin, V; Santiago, J | 1 |
| Hattori, T; Naito, M; Takahashi, H; Taya, Y; Uchida, C; Yamamoto, N | 1 |
| Kim, JY; Kwon, OK; Lee, S; Sim, J; Yun, KN | 1 |
| Alayi, TD; Bissé, E; Epting, T; Schaeffer-Reiss, C; Van Dorsselaer, A | 1 |
| Fukuda, D; Masuzaki, H; Matsumoto, S; Sata, M; Shimabukuro, M; Soeki, T; Yamakawa, K | 1 |
| Fabrizio, P; Hu, J; Longo, VD; Mirisola, MG; Taormina, G; Wei, M | 1 |
| Avenoza, A; Aydillo, C; Busto, JH; Jiménez-Osés, G; Peregrina, JM; Zurbano, MM | 1 |
| Mayle, S; Monie, TP | 1 |
| Chari, A; Daub, H; Draeger-Meurer, S; Fischer, U; Gruss, OJ; Husedzinovic, A; Oppermann, F | 1 |
| Beauchamp, JL; Gao, J; Sohn, CH; Thomas, DA | 1 |
| Cherella, C; Copps, KD; Hançer, NJ; Li, Y; Qiu, W; White, MF | 1 |
| Aranda, J; Bou, G; Méndez, JA; Nakedi, K; Soares, NC; Spät, P | 1 |
| Baulard, A; Blondiaux, N; Carrère-Kremer, S; Dimala, MM; Kremer, L; Leiba, J; Molle, V; Wohlkönig, A | 1 |
| Amaral, AF | 1 |
| Bousquet, J; Loureiro, CC; Rocha, SM; Todo Bom, A | 1 |
| Gray, EE; Guglietta, R; Khakh, BS; O'Dell, TJ | 1 |
| Briggs, WR; Burlingame, AL; Deng, Z; Hao, L; Kutschera, U; Oses-Prieto, JA; Tseng, TS; Wang, ZY | 1 |
| Appukuttan, PS; Geetha, M; Kalaivani, V; Sabarinath, PS | 1 |
| Singh, JP; Wu, J; Yang, X; Zhang, K | 1 |
| Cai, HY; Gao, XP; Qi, JS; Qiao, F; Yuan, L | 1 |
| Li, X; Liu, H | 3 |
| Dennis, MD; Gordon, BS; Jefferson, LS; Kimball, SR; Martin, TD | 1 |
| Becker, W; Florencio Ortiz, V; Pasqualon, T; Schumacher, J; Soppa, U; Tejedor, FJ | 1 |
| Chwae, YJ; Hwang, SG; Jung, J; Kim, K; Park, S; Shin, HJ | 1 |
| Du, Y; Fu, H; Han, Q; Khuri, FR; Li, Z; Park, HR; Pham, CD; Shi, Z; Zhang, Y | 1 |
| Kazemnezhad Leili, E; Masoudi Rad, H; Rabiei, M; Rahbar Taramsar, M; Sadegh Khanjani, M; Sobhani, A | 1 |
| Craig, RW; Kasof, G; Nifoussi, SK; Ornstein, DL; Ratcliffe, NR; Strack, S | 1 |
| Arnosti, DN; Elenbaas, J; Heinze, K; Henry, RW; Pushel, I; Wei, Y; Zhang, L | 1 |
| Hou, S; Huang, B; Qin, Q; Wang, W; Xu, X; Yan, L; Yue, J; Zhang, J | 1 |
| Ayers, PW; Verstraelen, T; Vöhringer-Martinez, E | 1 |
| Grundner, C; Sherman, DR | 1 |
| Asensio, JL; Avenoza, A; Berbis, MÁ; Busto, JH; Corzana, F; García-García, L; Hurtado-Guerrero, R; Jiménez-Barbero, J; Madariaga, D; Martín-Santamaría, S; Martínez-Sáez, N; Peregrina, JM; Somovilla, VJ; Valero-Gónzalez, J | 1 |
| Bethel, CR; Bonomo, RA; George, AC; LaCuran, AE; Liu, EM; Oelschlaeger, P; Pegg, KM | 1 |
| Bejar, S; Ben Hlima, H; Ben Mabrouk, S; Hmida Sayari, A; Mezghani, M; Zouari Ayadi, D | 1 |
| Cox, J; D'Souza, RC; Mann, M; Schaab, C; Sharma, K; Tyanova, S; Wiśniewski, JR | 1 |
| El Khatib, M; Molander, GA | 1 |
| Calleja, V; de Las Heras-Martinez, G; Laguerre, M; Larijani, B; Parker, PJ; Requejo-Isidro, J | 1 |
| Dou, Z; Fu, C; Wang, X; Wang, Z; Xu, L; Yu, H; Zheng, F; Zhu, T | 1 |
| Hu, SJ; Huang, HC; Lin, J; Ma, GX; Zhou, RQ | 1 |
| Lee, CL; Li, X | 1 |
| Bode, JW; Harmand, TJ; Murar, CE | 1 |
| Altmann, F; Grabherr, R; Staudacher, E; Taus, C; Windwarder, M | 1 |
| Barak, S; Batushansky, A; Fait, A; Fernie, AR; Khan, A; Nikoloski, Z; Scossa, F; Toubiana, D; Tzfadia, O; Zamir, D | 1 |
| Hao, Y; Nair, SK; Ortega, MA; van der Donk, WA; Walker, MC; Zhang, Q | 1 |
| Chang, RC; Ho, YS; Huang, C; Irwin, MG; Ng, OT; Wong, GT | 1 |
| Archambaud, C; Cao, TN; Cossart, P; Deutscher, J; Henry, C; Milohanic, E; Misra, SK; Monnet, V; Moussan Désirée Aké, F; Wu, Z | 1 |
| Li, Z; Liu, Z; Wu, P; Zhao, W; Zhao, Y | 1 |
| Dyckhoff, G; Freier, K; Freudlsperger, C; Grabe, N; Hess, J; Hoffmann, J; Horn, D; Plinkert, P; Saure, D; Sharma, S; Weber, KJ; Weichert, W; Weißfuß, S | 1 |
| Fedoreyev, SA; Han, J; Jeong, SH; Kim, HK; Kim, N; Ko, KS; Ko, TH; Lee, SR; Mischchenko, NP; Nilius, B; Pronto, JR; Rhee, BD; Song, IS; Stonik, VA; Youm, JB | 1 |
| Filtz, TM; Gafken, PR; Leid, M; Vogel, WK | 1 |
| Chan, SH; Cheriyan, M; Perler, F | 1 |
| Beaudry, K; Cagnol, S; Carrier, J; Lemieux, E; Rivard, N | 1 |
| Coco, MW; Rose, RB; Wang, D | 1 |
| Barchi, JJ; Biswas, S; Medina, SH | 1 |
| Ahmed, MH; Chowdhury, N; Contestabile, R; di Salvo, ML; Gandhi, A; Ghatge, MS; Kellogg, GE; Musayev, FN; Remesh, SG; Safo, MK; Schirch, V | 1 |
| Huang, SY; Liu, MC; Qiu, JD; Shi, SP | 1 |
| Chen, Z; Di Cera, E; Gohara, DW; Pelc, LA; Pozzi, N; Vogt, AD | 1 |
| Chakraborti, PK; Karthikeyan, S; Kumar, S; Ravala, SK; Singh, S; Yadav, GS | 1 |
| Braiterman, LT; Chaerkady, R; Cole, RN; Gupta, A; Hubbard, AL | 1 |
| Inoue, T; Koizumi, S; Nakamura, H; Narita, K; Okazaki, S; Sasamoto, S; Takeda, S | 1 |
| Fischer, S; Garcia, KC; Jude, KM; Luca, VC; Nachury, MV; Pierce, NW | 1 |
| Hamelberg, D; Velazquez, HA | 1 |
| Bisconte, MG; Caldora, M; Cardiero, G; Flagiello, A; Gaudiano, C; La Porta, G; Lacerra, G; Lagona, L; Medulla, E; Merlino, A; Musollino, G; Prezioso, R; Pucci, P; Qualtieri, G | 1 |
| Adamberg, K; Aller, K; Peebo, K; Reile, I; Timarova, V; Vilu, R | 1 |
| Adamo, ME; Hogan, DA; Kettenbach, AN; Liu, Z; Myers, LC; Olarte, RA; Stajich, JE; Willger, SD | 1 |
| Chen, XH; Li, H; Peng, XX; Wen, C; Wu, CW; Wu, XJ; Zhao, XL | 1 |
| Karmakar, P; Misra, S; Mukherjee, A | 1 |
| Burmeister, BT; Carnegie, GK; Gold, MG; O'Bryan, JP; Skidgel, RA; Wang, L | 1 |
| Álvarez, E; Boto, A; Romero-Estudillo, I; Saavedra, C | 1 |
| Foulquier, E; Galinier, A; Grangeasse, C; Pompeo, F; Serrano, B | 1 |
| Gruber, K; Mink, D; Oberdorfer, G; Riegler-Berket, L; Schürmann, M; Steinkellner, G; Uhl, MK; van Assema, F | 1 |
| de Graaf, C; de Munnik, SM; Kooistra, AJ; Leurs, R; Nijmeijer, S; Smit, MJ; van Offenbeek, J; Vischer, HF | 1 |
| Ahmadi, H; Helmbrecht, A; Rodehutscord, M; Siegert, W | 1 |
| Abraham, NG; Canestraro, M; Cao, J; Lee, CR; Schwartzman, ML; Vanella, L; Zeldin, DC | 1 |
| Azevedo, AW; Baameur, F; Chen, J; Doan, T; Gurevich, VV; Homan, KT; Moaven, H; Rieke, F; Sokal, I; Tesmer, JJ; Vishnivetskiy, SA | 1 |
| Goto, Y; Liu, Z; Musier-Forsyth, K; Novoa, EM; Ribas de Pouplana, L; Suga, H; Vargas-Rodriguez, O | 1 |
| Schulze, WX; Xu, D; Yao, Q | 1 |
| Bjes, ES; Fan, JY; Means, JC; Price, JL | 1 |
| Bian, Y; Cheng, K; Wang, F; Ye, M; Zou, H | 1 |
| Ağar, G; Anar, M; Öğütçü, H; Özkan, EH; Şakıyan, İ; Sarı, N | 1 |
| Bjekić-Macut, J; Božić-Antić, I; Korićanac, G; Macut, D; Matić, G; Milutinović, DV; Nikolić, M; Rodaljević, S; Stanišić, J; Tepavčević, S | 1 |
| Lam, HY; Lee, CL; Li, X | 1 |
| Ma, GX; Song, ZH; Zeng, YQ; Zhou, RQ; Zhou, ZY; Zhu, HH | 1 |
| Komatsu, S | 1 |
| Gaillard, T; Hellwig, P; Stote, RH; Trivella, A | 1 |
| Chaudhuri, R; Humphrey, SJ; James, DE; Ma, X; Parker, BL; Peterman, S; Yang, G | 1 |
| Anastasiadis, PZ; Copland, JA; Huveldt, D; Kourtidis, A; Yanagisawa, M | 1 |
| de Brevern, AG; Karboune, S; Rebehmed, J; Seo, S | 1 |
| Asensio, JL; Avenoza, A; Bernardes, GJ; Busto, JH; Castro-López, J; Compañón, I; Corzana, F; Hurtado-Guerrero, R; Jiménez-Barbero, J; Madariaga, D; Martínez-Sáez, N; Peregrina, JM; Salvadó, M; Somovilla, VJ; Valero-González, J | 1 |
| Bailey, R; Giasson, BI; Hamm, M; Lewis, J; Shaw, G; Yen, SH | 1 |
| Gui, Y; Li, L; Shi, Z; Singh, P; Walsh, MP; Yin, H; Yu, YN; Zheng, XL; Zhou, YX | 1 |
| Kirken, RA; Ross, JA; Ruiz-Medina, BE | 1 |
| Dengjel, J; Engel, C; Müller, B; Ramachandran, H; Walz, G; Yakulov, TA | 1 |
| Ané, JM; Coon, JJ; Nguyen, TT; Rose, CM; Sussman, MR; Venkateshwaran, M; Volkening, JD; Westphall, MS | 1 |
| Derouiche, A; Kalantari, A; Mijakovic, I; Shi, L | 1 |
| Hawke, DH; Lee, JH; Li, X; Lu, Z; Lyu, J; Qian, X; Wang, Y; Xia, Y; Zhang, G; Zheng, Y | 1 |
| An, N; Meng, X; Sun, H; Wang, H; Wang, X; Yan, G; Zhang, A; Zhang, Y | 1 |
| Compton, DA; Dmitrovsky, E; Freemantle, S; Godek, K; Hu, S; Kawakami, M; Lu, Y; Mustachio, LM; Orr, B; Sekula, D | 1 |
| Jiang, Y; Wang, M; Xu, X | 1 |
| Ahmad, F; Hassan, MI; Islam, A; Naz, F | 1 |
| Brooks, CL; Goto, JJ; Grover, SK; Gunasekara, SM; Hicks, MN; Lee, JW; Park, J; Saunders, CV; Serate, J; Youn, H | 1 |
| Chen, WX; Liu, T; Tian, CF | 1 |
| Ha, C; Lim, K | 1 |
| Kim, D; Ntui, VO; Xiong, L; Zhang, N | 1 |
| Cheng, K; Huang, J; Pan, Y; Qin, H; Yao, Y; Ye, M; Zou, H | 1 |
| Alfonso, I; Faggi, E; Luis, SV; Vicent, C | 1 |
| Dautel, R; Harter, K; Heunemann, M; Schulze, WX; Wu, XN | 1 |
| Lohani, CR; Palmer, M; Taylor, R; Taylor, SD | 1 |
| Dickey, DM; Edmund, AB; Egbert, JR; Jaffe, LA; Potter, LR; Shuhaibar, LC; Uliasz, TF; Yee, SP | 1 |
| Bi, S; Ling, B; Sun, M; Yan, X | 1 |
| Ding, K; Jeyabal, PV; Shi, ZZ; Song, R; Wang, G; Weiskoff, AM; Xu, D | 1 |
| Harayama, H; Ishikawa, S; Isono, A; Nakamura-Mori, K; Noda, T; Tate, S | 1 |
| Kwan, AH; Lyons, B; Truscott, RJ | 1 |
| He, E; Li, W; Wang, J; Yan, G; Zhang, J | 1 |
| Chin, AF; Elam, WA; Hilser, VJ; Schrank, TP; Toptygin, D | 1 |
| Ernst, R; Gilliland, GL; Lacy, ER; Liu, X; Luo, J; Malia, TJ; Mercken, M; Sweet, RW; Teplyakov, A; Vandermeeren, M; Wu, SJ | 1 |
| De la Rosa, MA; Díaz-Moreno, I; Díaz-Quintana, A; Guerra-Castellano, A; Velázquez-Campoy, A | 1 |
| Eriani, G; Liu, RJ; Ruan, ZR; Wang, ED; Wang, Y; Zhou, XL | 1 |
| Doucette, AA; Zheng, S | 1 |
| Amicosante, G; Bottoni, C; Celenza, G; Colapietro, M; Galleni, M; Kerff, F; Marcoccia, F; Matagne, A; Mercuri, PS; Perilli, M; Sabatini, A | 1 |
| Hirano, K; Hirano, M | 1 |
| Gastecki, ML; Jurrissen, TJ; Padilla, J; Rector, RS; Sheldon, RD; Vieira-Potter, VJ; Woodford, ML; Zidon, TM | 1 |
| Alvarez-Curto, E; Butcher, AJ; Hudson, BD; Miller, AM; Milligan, G; Prihandoko, R; Tobin, AB; Ulven, T | 1 |
| Bobersky, S; Gretarsdóttir, JM; Metzler-Nolte, N; Suman, SG | 1 |
| Andersen, PM; Böhm, S; Borck, G; Brenner, D; Danzer, KM; Hübers, A; Kassubek, J; Ludolph, AC; Lulé, D; Meitinger, T; Müller, K; Neuwirth, C; Otto, M; Strom, TM; Volk, AE; Wahlqvist, M; Weber, M; Weishaupt, JH; Weydt, P; Wieland, T | 1 |
| Oner, DA; Tastan, H | 1 |
| Arendt, CS; Groll, M; Heinemeyer, W; Hochstrasser, M; Huber, EM; Li, X | 1 |
| Admon, A; Ahn, NG; Beenstock, J; Engelberg, D; Garfinkel, BP; Melamed, D; Mooshayef, N; Mordechay, D | 1 |
| Babiec, WE; Guglietta, R; O'Dell, TJ | 1 |
| Iwasawa, K; Kobayashi, O; Shimizu, K; Uchida, M | 1 |
| Johnstone, SR; Lohman, AW; Straub, AC | 1 |
| Aro, EM; Lundin, B; Rantala, M; Suorsa, M; Trotta, A | 1 |
| Li, B; Ling, C; Ma, W; Srivastava, A | 1 |
| Albac, C; Allinquant, B; Dorard, E; Gorisse-Hussonnois, L; Guihenneuc-Jouyaux, C; Potier, MC | 1 |
| Armutlulu, A; Balaram, H; Balasubramanian, S; Bartosh, TJ; Broda, M; Brown, LE; Burroughs, LM; Burrows, F; Cardoso, JR; Carregaro, RL; Cho, J; Cui, Q; Dela Bela, LF; Dias, JM; Dutta, NK; Flowers, ME; Gallo, S; Hari, P; He, R; He, Y; Heimfeld, S; Jia, B; Jin, X; Jin, YJ; Karakousis, PC; Karmakar, T; Kiem, HP; Kreager, DA; Lebedev, D; Li, F; Li, S; Liang, N; Liu, Z; Luo, J; Luo, Y; Mazuquin, BF; Meng, Y; Mosialos, G; Moura, FA; Müller, CR; Naeem, MA; Nagappa, LK; Nguyen, H; Pelegrinelli, AR; Pinn, ML; Prahlada Rao, VS; Pulsipher, MA; Ragan, DT; Richards, J; Roy, S; Sandmaier, BM; Selfe, J; Selim, MA; Shi, J; Shi, X; Staff, J; Storb, R; Storer, BE; Wang, F; Wang, M; Wang, S; Woolfrey, AE; Wright, T; Ylostalo, JH; Zhang, JY; Zhang, ZY; Zheng, K; Zhu, Z | 1 |
| Bae, JS; Chung, MJ; Jang, KY; Kim, KM; Moon, WS; Noh, SJ; Park, BH; Park, HS | 1 |
| Bowness, P; Chen, L; Shi, H; Yuan, J | 1 |
| Chandrashekarappa, DG; Garnar-Wortzel, L; McCartney, RR; Schmidt, MC | 1 |
| Cai, X; Chu, Y; Fan, D; Fan, X; Horvath, T; Jiang, M; Li, X; Liang, J; Nie, Y; Qiu, Z; Wang, W; Wu, K; Xu, B; Yang, X; Zhang, S; Zhang, X; Zhou, J | 1 |
| Andreeva, S; Buvall, L; Choi, HY; Greka, A; Mundel, P; Sieber, J; Wallentin, H | 1 |
| Carney, EF | 1 |
| Ishihama, Y; Lin, MH; Periasamy, S; Suriyanarayanan, T; Swarup, S | 1 |
| Murata, M; Noda, K | 1 |
| Atomi, H; Hachisuka, SI; Imanaka, T; Kawamura, H; Makino, Y; Sato, T; Takeno, R | 1 |
| Beitia, M; Calzia, D; Morelli, A; Panfoli, I; Ponassi, M; Ravera, S; Rosano, C | 1 |
| Dagnino, L; Singh, RK | 1 |
| Kim, JK; Liu, H; Luo, T | 1 |
| Li, T; Li, X; Liu, H | 1 |
| Arnold, FH; Buller, AR; Murciano-Calles, J; van Roye, P | 1 |
| Asselman, J; Beert, E; De Coninck, DI; De Schamphelaere, KA; Decaestecker, E; Janssen, CR; Orsini, L; Pfrender, ME | 1 |
| de Godoy, LM; Goldenberg, S; Krieger, MA; Picchi, GF; Zanchin, NT; Zulkievicz, V | 1 |
| Godfrey, M; Jones, A; Kataria, M; Snijders, AP; Touati, SA; Uhlmann, F | 1 |
| Sakurai, H | 1 |
| Bej, AK; Crowley, M; Eipers, PG; Hakim, JA; Koo, H; Kumar, R; Lefkowitz, EJ; Morrow, CD; Powell, ML; Watts, SA | 1 |
| Fiedler, D; Marmelstein, AM; Moreno, J | 1 |
| Abts, A; Clemens, R; Reiners, J; Schmitt, L; Smits, SH | 1 |
| Fiedler, D; Krause, E; Penkert, M; Perlman, D; Schümann, M; Yates, LM | 1 |
| Giehr, P; Lan, J; Lepikhov, K; Walter, J | 1 |
| Bosma, T; de Vries, L; de Vries, MP; Kuipers, A; Moll, GN; Rink, R | 1 |
| Huang, B; Kuang, Y; Liu, G; Liu, W | 1 |
| Ansari, AZ; Eick, D; Florens, L; Gasch, AP; Gilmore, JM; Heidemann, M; Hintermair, C; Ho, YH; Nemec, CM; Tseng, SC; Varani, G; Washburn, MP; Yang, F; Zhang, Y | 1 |
| Jasnovidova, O; Krejcikova, M; Kubicek, K; Stefl, R | 1 |
| Chan, TH; Chen, S; Jin, K; Lau, HT; Li, X; Po, KHL; Reuven, JA; Wai, CN; Wang, S | 1 |
| Eng, GWL; Virshup, DM | 1 |
| Armstrong, D; Bancerz, M; Cabral, AD; de Araujo, ED; Duodu, E; Fekl, U; Fong, R; Gardiner, JE; Gunning, PT; Kraskouskaya, D; Rosa, D; Toutah, K | 1 |
| Butler, A; Reitz, ZL; Sandy, M | 1 |
| Fujihara, A; Maeda, N | 1 |
| Craven, TW; De Leon, CA; Levine, PM; Pratt, MR | 1 |
| Fukazawa, J; Ishida, S; Ito, T; Oe, S; Takahashi, Y | 1 |
| Ayté, J; Carmona, M; Hidalgo, E; Oliva, B; Paulo, E; Salat-Canela, C; Sánchez-Mir, L | 1 |
| Ahmad, S; Hasan, MAM; Molla, MKI | 1 |
| Hill, JM; Leskoske, KL; Martinez Marshall, MN; Roelants, FM; Thorner, J | 1 |
| Bihaqi, SW; Eid, A; Zawia, NH | 1 |
| Biondi, RM; Brieger, A; Hinrichsen, I; Huhn, M; Passmann, S; Plotz, G; Weßbecher, IM; Zeuzem, S | 1 |
| Manley, JL; Yurko, NM | 1 |
| Chen, X; Chen, Y; Dong, J; Stauffer, S; Zeng, Y; Zhou, J | 1 |
| Baulieu, EE; Byrne, C; Cantrelle, FX; Chambraud, B; Despres, C; Huvent, I; Jacquot, Y; Landrieu, I; Lippens, G; Qi, H; Smet-Nocca, C | 1 |
| Clapham, DE; Krapivinsky, G; Krapivinsky, L; Manasian, Y; Renthal, NE; Santa-Cruz, A | 1 |
| El Atmioui, D; Heck, AJR; Leney, AC; Ovaa, H; Wu, W | 1 |
| Bessho, Y; Chen, ES; Chen, YH; Huang, KF; Huang, WC; Kawano, Y; Liao, JH; Lim, LH; Liu, XX; Matsui, T; Tsai, MD; Wang, SC; Weng, JH; Wu, WJ | 1 |
| Bai, Y; Chen, B; Chen, M; Li, M; Ren, S; Wang, S; Xu, Q; Zhou, Y | 1 |
| Li, BQ; Li, SY; Liu, JJ; Wang, X; Xu, ML; Zhai, HL | 1 |
| Hu, CW; Jiang, J; Li, B; Li, H | 1 |
| Boto, A; Hernández, D; Saavedra, CJ | 1 |
| Araki, Y; Fukasawa, M; Okamoto, S; Osuka, K; Usuda, N; Wada, K; Wakabayashi, T; Watanabe, Y | 1 |
| Garvanska, DH; Hein, JB; Hertz, EPT; Kruse, T; Nilsson, J | 1 |
| Begley, V; Böttcher, R; Cavero, S; Chávez, S; de Nadal, E; Posas, F; Silva, A; Solé, C | 1 |
| Guo, Y; Jing, XP; Li, X; Liang, JW; Liu, R; Liuyang, ZY; Shentu, YP; Wang, JZ; Wang, XC; Zeng, J; Zhou, H; Zhou, XW | 1 |
| Jin, L; Matter, ML; Ramos, JW; Shi, GX; Yang, WS | 1 |
| Arkin, AP; Deutschbauer, AM; Kuehl, JV; Melnyk, RA; Price, MN; Wall, JD; Zane, GM | 1 |
| Bagó, AG; Bödör, C; Csala, I; Deák, B; Hajdu, M; Kriston, C; Marosvári, D; Nagy, N; Reiniger, L; Sebestyén, A; Szállási, Z | 1 |
| Ceylaner, S; Kör, D; Önenli-Mungan, N; Şeker-Yılmaz, B; Tümgör, G | 1 |
| Jia, C; Zuo, Y | 1 |
| Chang, SL; Liao, F; Lu, MY; Lu, SS | 1 |
| Hofmann, K; Knebel, A; Mabbitt, PD; Pao, KC; Rafie, K; Stanley, M; Sundaramoorthy, R; van Aalten, DMF; Virdee, S; Wood, NT | 1 |
| Bruno, F; D'Agata, V; D'Amico, AG; Federico, C; Gil, L; Saccone, S | 1 |
| Carlson, EE; Fihn, CA; Wilke, KE | 1 |
| Aweida, D; Ber, Y; Bialik, S; Cohen, S; Eisenstein, M; Gilad, Y; Kimchi, A; Shiloh, R | 1 |
| Furukawa, Y; Kotani, M; Nakajima, M; Nakamura, K; Okuyama, S; Sawamoto, A; Shinoka, W; Sudo, M; Sugawara, K | 1 |
| Gokulrangan, G; Karn, J; Mbonye, U; Shi, W; Wang, B; Yang, S | 1 |
| Ali, FM; Cheng, ZX; Li, WX; Lin, XM; Peng, B; Su, YB; Ye, JZ; Zheng, J | 1 |
| Brutkowski, W; Fabczak, H; Gaertig, J; Jedynak, K; Jerka-Dziadosz, M; Joachimiak, E; Krzemień-Ojak, Ł; Sas-Nowosielska, H; Urbanska, P; Wacławek, E; Wloga, D | 1 |
| Balasuriya, N; Biggar, KK; Kunkel, MT; Li, SS; Liu, X; Newton, AC; O'Donoghue, P | 1 |
| Beg, AA; Chan, PY; Freeman, RS; Gabay, M; MacConnachie, L; Papasergi-Scott, MM; Stoveken, HM; Tall, GG; Wong, D | 1 |
| Saraji, M; Yousefi, S | 1 |
| Chen, W; Li, Y; Miao, B; Wang, Z; Xiao, Q | 1 |
| Schey, KL; Wang, Z | 1 |
| Attems, J; Daum, G; Flunkert, S; Hoeller, C; Hutter-Paier, B; Kerschbaumer, B; Loeffler, T; Neddens, J; Niederkofler, V; Temmel, M | 1 |
| Han, H; Kulynych, T; Li, J; Nyporko, A; Peng, Q; Powles, S; Yu, Q | 1 |
| Alexander, WM; Amzel, LM; Chen, Z; Chu, N; Cole, PA; Dempsey, DR; Ficarro, SB; Gabelli, SB; Li, Y; Liu, AZ; Marto, JA; Salguero, AL | 1 |
| Cai, Y; Jin, J; Shah, JA; Zhao, L | 1 |
| Escalante-Semerena, JC; Tavares, NK; VanDrisse, CM | 1 |
| Cui, D; Jia, H; Liu, T; Si, Y; Wang, H; Wang, L; Xue, H; Zhao, Y | 1 |
| Cole, PA; Dempsey, DR | 1 |
| Choudhury, D; Dixit, A; Kaur, J; Khan, MJ; Sen, S; Singh, MK; Yadav, NS | 1 |
| Dickey, DM; Dumoulin, A; Feil, R; Kühn, R; Octave, M; Potter, LR; Rathjen, FG; Robinson, JW; Schmidt, H | 1 |
| Devamani, T; Lee, S; Levy, B; Lippert, LG; Ma, N; Sandhu, M; Sivaramakrishnan, S; Vaidehi, N | 1 |
| Jung, JH; Kim, YS; Lee, SM; Seo, JA | 1 |
| Smith, PF; Stiles, L; Zheng, Y | 1 |
| Jenkins, A; Moody, OA | 1 |
| Jurásková, V; Vondrášek, J; Vymětal, J | 1 |
| Jin, X; Wei, Y; Yu, H; Zhou, J | 1 |
| Barb, AW; Falconer, DJ; Subedi, GP | 1 |
| Chattopadhyay, A; Itzhaki, LS; Johnson, CM; Neira, JL; Rowling, PJE; Tan, YS; Verma, CS; Yadahalli, S | 1 |
| Asara, JM; Attri, KS; Bhinderwala, F; Gong, W; Green, DR; Herring, LE; Kalil, AC; Lei, YL; Lewis, RE; Li, T; Li, X; Powers, R; Rodriguez, DA; Singh, PK; Wang, H; Wen, H; Yang, M; Yang, X; Yin, G | 1 |
| Han, J; Han, S; Li, J; Liang, Y; Liu, Y; Liu, Z; Ma, H; Zhang, Z; Zhong, CQ | 1 |
| Giogha, C; Lawlor, KE | 1 |
| Arsenault, RJ; Pagano, GJ | 1 |
| Benkovic, SJ; Cantley, LC; He, J; Johnson, JL; Knudsen, GM; Liu, C; Pedley, AM; Yaron, TM | 1 |
| Azam, M; Dwivedi, P; Greis, KD; Grimes, HL; Muench, DE; Wagner, M | 1 |
| Creixell, P; Haider, N; Joughin, BA; Linding, R; Miller, CJ; Simpson, CD; Stambolic, V; Turk, BE; van de Kooij, B; van Vlimmeren, A; Yaffe, MB | 1 |
| Limpikirati, P; Pan, X; Vachet, RW | 1 |
| Kang, W; Liu, KH; Oh, S; Shin, S; Son, Y | 1 |
| Arthur, JSC; Cohen, P; Kelsall, IR; Knebel, A; Zhang, J | 1 |
| Hayes, A; Kruzliak, P; Rai, S; Smith, RM; Zulli, A | 1 |
| Bagum, H; Christensen, KE; Genov, M; Moloney, MG; Pretsch, A; Pretsch, D | 1 |
| Chen, ZG; Cheng, ZX; Guo, C; Li, D; Li, H; Peng, B; Peng, XX; Wang, J; Yang, TC; Zhang, JY; Zhang, TT; Zhu, JX | 1 |
| Hassan, A; Maiti, S; Mitra, P | 1 |
| Barekatain, R; Girish, CK; Hilliar, M; Huyen, N; Swick, RA; Wu, S | 1 |
| Dumit, VI; Duyster, J; Gengenbacher, A; Gräßel, L; Illert, AL; Kreutmair, S; Lippert, LJ; Müller-Rudorf, A; Poggio, T | 1 |
| Forman-Kay, JD; Kay, LE; Kim, TH; Sonenberg, N; Tsang, B; Vernon, RM | 1 |
| Fuller, PJ; He, S; Jin, R; Martín-Fernández, B; Smith, BJ; Yao, YZ; Young, MJ | 1 |
| Bhardwaj, V; Blaha, GM; Diggs, S; Feeley, BE; Higgs, PI; McLaughlin, M | 1 |
| Cavanagh, AP; Finkemeier, I; Giese, J; Harvey, CM; Huber, SC; Kim, SY; Lassowskat, I; Ort, DR; Singh, V; Spalding, MH | 1 |
| Boomsma, W; Bugge, K; Fernandes, CB; Hendus-Altenburger, R; Kragelund, BB; Kunze, MBA | 1 |
| Koehler, CJ; Thiede, B | 1 |
| Gao, Y; Li, W; Liu, J; Rui, X; Si, D; Sun, X; Wang, C; Zhu, J; Zhu, Y | 1 |
| An, HJ; Cho, SJ; Cho, YY; Kang, HC; Kim, DJ; Kim, SM; Kim, WY; Lee, CJ; Lee, GE; Lee, HS; Lee, JY; Park, J; Yoo, SM | 1 |
| Barbot, T; Beswick, V; Cao, XX; Huang, DL; Jamin, N; Jaxel, C; Li, Y; Liang, J; Montigny, C; Tian, CL; Xue, M; Zheng, JS; Zheng, Y | 1 |
| Bisnett, BJ; Boyce, M; Chen, PH; Chi, JT; Condon, BM; Hu, J; Huynh, DT; Lu, A; Pan, S; Smith, AB; Smith, TJ; Wu, J | 1 |
| Di, P; Han, G; Han, T; Liu, L; Liu, W; Yan, J; Yu, X; Zhang, A | 1 |
| Chi, A; Yan, J; Yao, C; Zhao, S | 1 |
| Agbas, E; Cameron-Carter, H; Cui, W; Shen, X; Staudinger, JL; Tompkins, B | 1 |
| Blankenship, C; Estevez, A; Jiang, J; Zhu, D | 1 |
| Bräuning, B; Groll, M; Itzen, A; Kachariya, N; Lai, YC; Mulholland, K; Muqit, MMK; Sattler, M; Singh, PK; Toth, R; Vieweg, S; Volpi, I | 1 |
| Gulati, S; Ortiz, EA; Palczewski, K; Robinson, PR; Valdez-Lopez, JC | 1 |
| Brunner, JD; Jakob, RP; Maier, T; Moroni, A; Neldner, Y; Schenck, S; Schulze, T; Thiel, G | 1 |
| Garg, A; Sanchez, AM; Schwer, B; Shuman, S | 1 |
| Clausen, H; Daniel, EJP; García-García, A; Gerken, TA; Hurtado-Guerrero, R; Las Rivas, M; Lira-Navarrete, E | 1 |
| Arellano-Gutiérrez, CV; Bolaños, J; Contis-Montes de Oca, A; Fragozo-Sandoval, F; López-Casamichana, M; López-Reyes, I; Padilla-Mendoza, JR; Quintas-Granados, LI; Reséndiz-Albor, AA; Reyes-Hernández, OD; Rodríguez, MA | 1 |
| Bonne Køhler, J; Derouiche, A; Jers, C; Mijakovic, I; Senissar, M; Shi, L | 1 |
| Cant, JP; de Lange, CFM; Htoo, JK; Huber, LA; Mansilla, WD; Shoveller, AK; Silva, KE | 1 |
| Anderson, RM; Aon, MA; Bernier, M; Colman, RJ; de Cabo, R; Di Germanio, C; Ehrlich, MR; Mattison, JA; Mitchell, SJ | 1 |
| Arraiano, CM; Barahona, S; Galego, L; Romão, CV | 1 |
| Boggon, TJ; Chetty, AK; Ha, BH; Sexton, JA; Turk, BE | 1 |
| Bertinetti, D; Burghardt, NCG; Herberg, FW; Hornung, J; Knape, MJ; Lorenz, R; Schmidt, SH; Wallbott, M | 1 |
| Daniel, R; Gross, CA; Klewing, A; Koo, BM; Krüger, L; Poehlein, A; Reuß, D; Stülke, J | 1 |
| Sarker, A; Sayeem, MMS; Sharif Siam, MK | 1 |
| Chingsuwanrote, P; Issaragrisil, S; Jiamvoraphong, N; Klaihmon, P; Laowtammathron, C; Lorthongpanich, C; Srisook, P; U-Pratya, Y; Waeteekul, S | 1 |
| Machuqueiro, M; Oliveira, NFB; Pires, IDS | 1 |
| Babu, P; Khairnar, A; Ramya, TNC; Sunsunwal, S | 1 |
| Blum, Z; Robertsson, C; Svensäter, G; Wickström, C | 1 |
| Ahmed, S; Arif, M; Kabir, M; Khan, ZU; Yu, DJ | 1 |
| Ariño, J; Casamayor, A | 1 |
| König, S | 1 |
| Comly, M; Hanover, JA; Lamitina, T; Urso, SJ | 1 |
| Dong, S; Jing, H; Liu, T; Mu, Y; Obadi, M; Sun, J; Xu, B; Yang, Y | 1 |
| Barabas, O; Beullens, M; Bollen, M; Del Pino García, J; Derua, R; Fontanillo, M; Hoermann, B; Köhn, M; Salvi, F | 1 |
| Furutani, S; Hatta, T; Hattori, K; Ichijo, H; Natsume, T; Sakauchi, C; Sugawara, S; Wakatsuki, H | 1 |
| Cho, JW; Ji, S; Kang, MJ; Kim, E; Kim, YJ; Kweon, TH; Park, YS; Yang, WH; Yi, EC | 1 |
| Gretarsdottir, JM; Hambley, TW; Jonsdottir, S; Lewis, W; Suman, SG | 1 |
| Alain, T; Anton, L; Berman, AJ; Celucci, G; Chaker-Margot, M; Dajadian, C; Damgaard, CK; Fonseca, BD; Graber, TE; Hearnden, J; Hoang, HD; Hollensen, AK; Jia, JJ; Lahr, RM; Livingstone, M; Maier, T; Moraes, BJ; Niklaus, MR; Pena, IA; Pointet, R; Smith, EM; Solgaard, MT; Wang, XD; Yang, AD; Yu, Y | 1 |
| Baek, SA; Cha, SI; Choi, JE; Choi, SH; Do Yoo, J; Do, SK; Hong, MJ; Kang, HG; Kim, CH; Kim, JH; Kim, S; Lee, J; Lee, JH; Lee, SY; Lee, WK; Lee, YH; Park, JY; Seo, H; Yoo, SS | 1 |
| Bruzzone, S; Caudano, F; Damonte, G; Fedele, E; Montalto, G; Prickaerts, J; Ricciarelli, R; Salis, A; Sturla, L | 1 |
| Bai, X; Qi, Z; Xu, Y; Yao, K; Zhang, J; Zhang, M; Zhang, Y; Zu, H | 1 |
| Castro, A; Dasso, M; Gasmi-Seabrook, G; Gavet, O; Joly, N; Levinson, NM; Lorca, T; Mader, P; Maisonneuve, P; Orlicky, S; Pintard, L; Poteau, M; Regmi, SG; Sicheri, F; Tavernier, N; Thomas, Y; Van Hove, L; Velez-Aguilera, G; Vigneron, S | 1 |
| Cai, XR; Chi, YN; Huang, RQ; Miao, XY; Wang, CF; Xiao, BK; Yang, JY | 1 |
| Ha, Y; Kim, JY; Lee, JY; Nam, KH; Oh, MH; Shang, Y; Yang, D | 1 |
| Chao, A; Chi, LM; Jung, SM; Lee, YS; Lin, CY; Tsai, CL; Tsai, CN | 1 |
| Hoermann, B; Köhn, M | 1 |
| Kim, EJ | 1 |
| Chaudhari, M; Hicks, LM; Iannetta, AA; Kc, DB; Newman, RH; Roy, K; Thapa, N; White, C | 1 |
| Ayhan, A; Balcı-Hayta, B; Boztug, K; Cagdas, D; Cetinkaya, PG; Esenboga, S; Halacli, SO; Karaatmaca, B; Orhan, D; Ozen, S; Sanal, O; Tan, C; Tezcan, I; Topaloglu, R; Uner, A | 1 |
| Bennett, MJ; Bhosale, R; Borkar, AN; Brown, KM; Bucksch, A; Hanlon, MT; Kaeppler, SM; Lor, VSN; Lynch, JP; Perkins, A; Rodriguez, J; Schneider, HM; Zhang, X | 1 |
| Jurk, K; Shiravand, Y; Walter, U | 1 |
| Hu, Y; Jiang, B; Zhang, L; Zhang, Y | 1 |
| Ai, X; Pogwizd, SM; Yan, J | 1 |
| He, W; Li, P; Wu, G | 1 |
| Chen, X; Hou, Y; Wang, X; Yu, J; Zhao, L; Zhong, B | 1 |
| Borges, E; do Vale, ML; Gomes, AC; Marques, EF; Oliveira, IS; Pereira, C | 1 |
| Brezesinski, G; Rudert, R; Strati, F; Vollhardt, D | 1 |
| Kamanda, P; Martynova, T; Sim, C | 1 |
| Li, X; Liu, H; Pu, F; Wei, T; Wu, H | 1 |
| LeClaire, LTN; Rodriguez Perez, S; Thompson, NK; Wakarchuk, WW | 1 |
| Aydogan, Y; Berger, BT; Chaikuad, A; Drewry, DH; Knapp, S; Mandel, S; Mauer, S; Müller, S; Pohl, C; Russ, N; Schröder, M | 1 |
| Doubleday, PF; Gruber, CH; Johns, NI; Krishnan, A; Park, J; Raguz Nakic, Z; Sauer, U; Schastnaya, E; Wang, HH | 1 |
| Jimenez, SA; Mendoza, FA | 1 |
| Chen, BR; Chen, F; Du, C; Fan, Y; Gu, LF; Guo, XJ; Kong, XQ; Li, YF; Liu, L; Ma, Y; Shan, TK; Sun, JT; Sun, R; Wang, H; Wang, LS; Wang, ZM; Wei, TW; Wei, YY; Yang, TT | 1 |
| Li, X; Wang, J | 1 |
| Berrin, JG; Bissaro, B; Lombard, V; Longhi, S; Tamburrini, KC; Terrapon, N | 1 |
| Grangeasse, C; Lenoir, C; Nagarajan, SN | 1 |
| Li, M; Liu, Y; Lu, W; Na, B; Qin, H; Qing, G; Tang, M; Wang, D; Xiong, Y | 1 |
| Kashetti, V; Kuchana, V; Manga, V; Peddi, SKR; Sivan, S | 1 |
| Gehring, MP; Horne, CR; Hristova, K; Lechtenberg, BC; Light, TP; Matsumoto, MW; Pasquale, EB | 1 |
| Dervishi, E; Knol, EF; Mathur, P; Plastow, GS; Reimert, I; van der Zande, LE | 1 |
| Dutta, R; Garg, A; Kale, SS; Sarkar, C; Sharma, MC; Suri, A; Suri, V | 1 |
| Blahos, J; Durydivka, O; Gazdarica, M; Mackie, K; Noda, J; Novosadova, V; Pin, JP; Prezeau, L | 1 |
| Cho, K; Choi, SH; Kim, ES; Yoo, HY | 1 |
| Cordo', V; de Ru, AH; Friggen, AH; Hensbergen, PJ; Mohammed, Y; Smits, WK; van Veelen, PA | 1 |
| Ivarsson, Y; Kliche, J | 1 |
| He, JQ; Wang, M; Wu, S; Zhang, M | 1 |
| Fu, C; He, L; Huang, S; Huang, Y; Li, J; Liu, L; Niu, H; Peng, T; Tang, H; Wang, W; Xu, K; Xu, Y; Yang, X; Zhao, Y; Zhou, H | 1 |
| Evan Prince, S; Panchal, NK | 1 |
| Ding, Y; Liu, C; Ren, L; Shen, D | 1 |
| Cheng, YW; Deng, DX; Dong, G; Li, DJ; Li, EM; Liao, LD; Long, L; Wen, B; Wu, XD; Xu, LY; Zhang, ZD | 1 |
| Li, Y; Ping, Q; Wang, S | 1 |
| Cravatt, BF; Dix, MM; Kemper, EK; Zhang, Y | 1 |
| Alganem, K; Creeden, JF; Flight, RM; Hinds, TD; Hipp, JA; Imami, AS; Kipp, ZA; Lee, WH; Martinez, GJ; McCullumsmith, R; McMullen, MR; Moseley, HNB; Nagy, LE; Nawabi, AM; Roychowdhury, S; Softic, S; Weinman, SA; Xu, M | 1 |
| Arcon, JP; Burastero, O; Cabrera, M; Defelipe, LA; Durán, R; Lopez, ED; Marti, MA; Turjanski, AG | 1 |
| Fan, J; Feng, Y; Gao, W; He, X; Li, Y; Ni, H; Song, X; Yang, J | 1 |
| Friederich, MW; Gabel, L; Ghaloul-Gonzalez, L; Miller, K; Neira-Fresneda, J; Peck, C; Schlichting, L; Swanson, MA; Tong, S; Van Hove, JLK; Young, SP | 1 |
| Huang, R; Li, S; Miao, X; Xiao, B; Yang, J | 1 |
| Byers, SA; Coussens, LM; Daniel, CJ; Fan, G; Juarez, E; Ko, A; Link, JM; Munks, MW; Murugan, D; Pelz, C; Sears, RC; Taylor, KL; Wang, X | 1 |
| Haase, R; Hoch, H; Königshausen, E; Meyer-Schwesinger, C; Potthoff, SA; Quack, I; Rump, LC; Sellin, L; Stegbauer, J; Wiech, T; Woznowski, MP | 1 |
| Liu, R; Luo, H; Ma, Y; Wang, X; Zhang, H; Zhang, Q | 1 |
| Chung, Y; DO, SI; Kim, HS; Kim, S | 1 |
| Eroglu, EC; Kucukgoz Gulec, U; Paydas, S; Vardar, MA | 1 |
| Akita, T; Furusho, A; Hamase, K; Ide, T; Ishii, C; Mita, M; Oyaide, M | 1 |
| Aon, MA; Bernier, M; de Cabo, R | 1 |
| Curtis, GH; Hille, MB; Hirano, MS; Horton, EC; Huang, J; Kupai, A; Lackey, DL; Mathieson, CJ; Murayama, JF; Nakahara, H; Rodriguez, A; Shan, B; Voss, KM | 1 |
| Chen, L; Chen, Y; Deng, D; Liu, J; Liu, K; Shi, M; Tang, M; Wei, Y; Yang, T; Yang, Y; Yuan, X; Zhang, C; Zhou, Y | 1 |
| Hou, L; Jin, Y; Li, Y; Liu, R; Qiao, X; Song, L; Wang, L; Wang, S; Zhou, K | 1 |
| Cui, Y; Gao, L; Lu, D; Wang, S; Xu, J | 1 |
| Aro, EM; Bajwa, AA; Gerotto, C; Morosinotto, T; Trotta, A | 1 |
| Hu, L; Li, J; Ma, Z; Song, W; Yang, L | 1 |
| Li, X; Liu, J | 1 |
| Chen, DP; Chen, JB; Chen, JC; Chen, MS; Hou, J; Kan, A; Kuang, DM; Liu, XC; Lu, SX; Tang, YH; Wang, JC; Wei, Y; Xu, L; Zhang, R; Zhang, YJ; Zhou, ZG | 1 |
| Jayanthi, LD; Mannangatti, P; Ragu Varman, D; Ramamoorthy, S; Subler, MA; Windle, JJ | 1 |
| Li, R; Shi, W; Yan, Z; Yao, L | 1 |
| Ecker, AMV; Giacalone, D; Tan, S; Yap, RE | 1 |
| Bothra, A; Dhasmana, N; Gangwal, A; Goel, AK; Keshavam, CC; Kumar, N; Leppla, SH; Pomerantsev, AP; Sangwan, N; Singh, LK; Singh, Y | 1 |
| Ciani, E; Cosentino, L; De Filippis, B; Fuchs, C; Fuso, A; Medici, G; Mottolese, N; Pietraforte, D; Quattrini, MC; Talamo, MC; Urbinati, C | 1 |
| Anwar, S; Hasan, GM; Hassan, MI; Islam, A; Shahwan, M | 1 |
| Flibotte, S; Foster, L; Jan, E; Moon, KM; Stoynov, N; Warsaba, R | 1 |
| Chen, GS; Chen, SY; Hsieh, CC; Huang, SM; Lee, SP; Liu, ST | 1 |
| Hanessian, S; Hocine, S; Kiyeleko, S; Kotschy, A; Kuenemann, M; Mautino, G; Miallau, L; Mirguet, O; Nawrotek, A; Vuillard, LM | 1 |
| Bi, H; Fan, S; Gao, Y; Huang, M; Li, X; Liang, H; Qu, X; Tian, J; Wang, R; Yang, J; Yang, X; Zhang, S; Zhang, Y | 1 |
| He, S; Li, P; Li, ZH; Liu, B; Liu, L; Sun, C; Xing, S; Yu, D; Zhang, M | 1 |
| Andersen, A; Andersen, HJ; Bertram, HC; Birkedal, H; Hansen, AK; He, W; Nielsen, DS; Wittig, NK; Xie, Z; Zachariassen, LF | 1 |
| Cai, YF; Chen, JX; Fu, Y; Li, H; Mu, GL; Tu, Y; Wan, YG; Wan, ZY; Wang, J; Wang, MZ; Wang, Y; Wu, W | 1 |
| Christodoulou, C; Mavrommatis, A; Prandi, B; Righi, F; Sforza, S; Simoni, M; Tedeschi, T; Tsiplakou, E | 1 |
| Hu, Y; Muegge, I | 1 |
| Al-Mukh, H; Bouaboud, A; Issad, T; Pagesy, P | 1 |
| Gao, T; Wang, R; Zhang, H; Zhao, F | 1 |
| Li, Y; Sun, H; Wang, P; Wei, C; Zhang, Y | 1 |
| Cipollo, JF; Gao, S; Guo, B; Huang, S; Li, J; Ma, J; Yang, S; Yue, S; Zhang, W | 1 |
| Cheng, Y; Guo, Y; Jiang, W; Liu, C; Qian, H; Yang, F; Yao, W; Zhao, Y | 1 |
| Djorić, D; Kristich, CJ; Little, J; Minton, NE | 1 |
| Ping, X; Stark, JM | 1 |
| Ates, O; Toker, EB; Yesilbag, K | 1 |
| Bento, I; Egri, P; Kirsch, K; Németh, K; Póti, ÁL; Reményi, A; Sok, P; Takács, T; Tusnády, GE; Zeke, A | 1 |
| Cloyd, JM; Du, S; Mao, Y; Pawlik, TM; Xiao, Y; Xu, G; Zhang, B | 1 |
| Du, ZX; Li, Y; Wang, ZJ; Yang, JH; Zhou, DM | 1 |
| Chen, F; Li, S; Liu, H; Liu, J; Lv, L; Shao, H; Tang, R; Yu, C; Yuan, K; Zhang, J; Zhang, Q | 1 |
| Addo, KA; Huang, YY; Huang, ZX; Li, H; Xiao, XL; Yu, YG | 1 |
| Gao, Y; Li, L; Li, Y; Xiu, M | 1 |
| Chen, B; Ding, M; Guan, L; Ma, X; Zhao, T; Zou, W | 1 |
| Huang, J; Li, S; Li, Y; Xiao, Q; Yang, H | 1 |
| Barker, O; Boyd, C; Feutren-Burton, S; Gavory, G; Gibson, H; Harrison, T; Jordan, L; McLean, E; O'Dowd, CR; O'Rourke, M; Page, N; Rountree, JSS; Trevitt, G; Wappett, M; Zhang, L | 1 |
| Hittinger, CT; Krause, DJ | 1 |
| Chen, L; Hao, Y; Liu, X; Shi, X; Yan, W; Yang, B; Yang, J; Yang, X; Zhang, D; Zhang, K; Zhao, D; Zheng, H | 1 |
| Bertini, S; Bononi, G; Caligiuri, I; Ceni, C; Di Stefano, M; Galati, S; Granchi, C; Macchia, M; Ortore, G; Poli, G; Rizzolio, F; Tuccinardi, T | 1 |
| Rawel, HM; Rohn, S; Sagu, ST | 1 |
| Chen, L; Gu, J; Huang, C; Kong, Q; Lin, D; Lu, R; Wu, W | 1 |
| Maitra, S; Vincent, B | 1 |
| Ding, T; Gao, L; Ge, J; Gu, Q; Ma, X; Shen, W; Wang, H; Xue, F; Zhang, X | 1 |
| Agorreta, J; Amat, R; Bértolo, C; Bosco, G; Calvo, A; Echepare, M; Felip, E; Frigola, J; López-Picazo, JM; Melero, I; Montuenga, LM; Pasquier, A; Picabea, B; Sainz, C; Tamayo, I; Teijeira, Á; Thomas, R; Valencia, K | 1 |
| Davey, NE; de Curtis, I; Lamarca, A; Ripamonti, M; Surini, S; Tonoli, D | 1 |
| Almilaibary, A | 1 |
| Arayamethakorn, S; Bordini, M; Davoli, R; Malila, Y; Petracci, M; Rungrassamee, W; Sanpinit, P; Sirri, F; Soglia, F; Thanatsang, KV; Zappaterra, M | 1 |
| Liu, Q; Liu, X; Shen, X; Sun, H; Sun, S; Wang, Y; Zhang, L | 1 |
| Köhn, M; Kokot, T | 1 |
| Cao, L; Chen, X; Han, Y; Jin, Y; Lv, Y; Qu, X; Zhang, J; Zhang, Y | 1 |
| Capiati, DA; Grossi, C; Muñiz García, MN; Ulloa, RM | 1 |
| Chávez-Maldonado, JP; Hiriart, M; Larqué, C; Ortiz-Huidobro, RI; Sabido, J; Sanchez-Zamora, YI; Velasco, M | 1 |
| Chao, M; Dong, J; Hu, G; Huang, L; Li, Y; Ren, R; Wang, Q; Zhang, J | 1 |
| Bhujbal, SP; Hah, JM; He, W | 1 |
| Green, DR; Tummers, B | 1 |
| Araki, E; Cai, W; Fukuda, K; Fukuda, T; Igata, M; Kahn, CR; Kondo, T; Okagawa, S; Okubo, Y; Otsuka, Y; Sakaguchi, M; Sakaguchi, N; Sato, Y; Tseng, YH; Yamagata, K; Yoshizawa, T | 1 |
| Calvanese, M; Colarusso, A; Lauro, C; Parrilli, E; Tutino, ML | 1 |
| Alganem, K; Creeden, JF; Imami, AS; Mathis, V; McCullumsmith, R; Wegman-Points, L; Yuan, LL | 1 |
| Ai, R; Cai, L; Hu, Q; Lai, M; Li, J; Li, L; Li, S; Shi, C; Xu, J; Ye, K; Zhen, J; Zhou, J | 1 |
| Chen, D; Dai, S; Geng, Y; Huang, X; Li, Z; Lu, L; Ouyang, P; Zhang, X; Zhu, H | 1 |
| Cuenot, E; Douché, T; El Omrani, N; Garcia-Garcia, T; Giai Gianetto, Q; Martin-Verstraete, I; Matondo, M; Poncet, S; Smits, WK | 1 |
| Breuhahn, K; Fernández-Palanca, P; Ghallab, A; Hassan, R; Hengstler, JG; Keegan, L; Kummer, U; Le Marois, M; Roessler, S; Sahle, S; Schirmacher, P; Schmitt, J; Tang, Y; Wehling, L | 1 |
| Lagerlöf, O; Uygar, B | 1 |
| Ahmed, F; Dehzangi, I; Hasan, MM; Shatabda, S | 1 |
| Ding, D; Hou, X; Huang, H; Jimenez, R; Shi, L; Tian, Y; Wang, L; Weroha, SJ; Zheng, R | 1 |
| Aguet, F; Anand, SK; Beausoleil, SA; Blenis, J; Bulaon, DK; Burke, KN; Cantley, LC; Chaparian, RR; Chen, S; Cohen, BM; Davidson, AD; Elemento, O; Getz, G; Hamele, CE; Harding, AT; He, L; Heaton, BE; Heaton, NS; Heesom, K; Hornbeck, PV; Johnson, JL; Jordan, TX; Kastenhuber, ER; Kavanagh-Williamson, M; Kerelsky, A; Koundouros, N; Lee, G; Levy, TM; Liberatore, KM; Lin, TY; Matthews, DA; Mercadante, MN; Nilsson-Payant, BE; Piskounova, E; Possemato, AP; Schwartz, RE; Shobana-Ganesh, K; Smith, CM; Tata, A; Tata, PR; tenOever, BR; Tkachev, SL; Trimarco, JD; Van Nest, SJ; Weinstein, H; Yaron, TM; Zhu, X | 1 |
| Kang, W; Wang, C; Wang, Z; Wu, Y; Xue, C; Zhang, Y; Zhu, C | 1 |
| Li, J; Lu, Q; Pan, D; Rong, W; Wang, A; Wang, L; Zhang, Y; Zhou, Q; Zhu, Q; Zhu, Y | 1 |
| Fujino, Y; Inazu, T; Kitano, A; Morii, A; Nagase, M; Takeuchi, K; Ueno, S; Yamashita, R; Yoshimura, Y | 1 |
| Ahmad, H; Ahmad, N; Chen, M; Du, J; Jin, Y; Khan, A; Li, X; Ouyang, Y; Tian, Z; Yang, P; Yang, Z; Zeng, L; Zhao, X; Zheng, X | 1 |
| Lin, X; Tu, H; Xiong, W; Zhang, J; Zhao, X | 1 |
| Bilgin, N; Boltje, TJ; Elferink, H; Hintzen, JCJ; Mecinović, J; Merx, J; Park, J; Porzberg, MRB; Proietti, G; Sondag, D; Wang, Y | 1 |
| Ayati, M; Bermea, KC; Everett, AD; Foster, DB; Fu, Z; Gabrielson, K; Heravi, A; Kim, HB; Medina, A; Murphy, AM; Na, CH; Paolocci, N; Ramirez-Correa, GA; Xu, M; Yang, X; Zhang, X | 1 |
| Andersen, JL; Ashworth, SW; Egbert, CM; English, N; Heaton, MJ; Pennington, KL; Thornton, MM; Torres, MP; Vaughan, AJ; Warr, LR | 1 |
| Akimov, V; Blagoev, B; Cohen, P; McCrory, EH | 1 |
| Alshafie, W; Ayoubi, R; Durcan, TM; Edwards, AM; Fotouhi, M; Laflamme, C; McPherson, PS; Shlaifer, I | 1 |
| Hu, J; Ou, J; Ou, S | 1 |
| Honda, K; Ma'ruf, IF; Restiawaty, E; Syihab, SF | 1 |
| Gizzio, J; Haldane, A; Levy, RM; Thakur, A | 1 |
| Fu, ZZ; Huang, QL; Jiang, RY; Wu, DP; Wu, XJ; Yan, S; Yang, BY; Yang, LL; Zhao, RR | 1 |
| An, J; Jia, X; Li, X; Liu, R; Liu, S; Mo, Y; Wei, X; Zhang, S; Zhang, Y; Zhou, L | 1 |
| Fulem, M; Havlín, J; Pokorný, V; Růžička, K; Štejfa, V | 1 |
| Lai, ML; Li, AQ; Neely, GG; Senior, AM; Simpson, SJ; Wang, QP | 1 |
| Brzozowski, JS; Dun, MD; Humphrey, SJ; Kahl, RGS; Miller, K; Murray, HC; Smith, ND; Verrills, NM | 1 |
| Chen, D; Li, WJ; Wang, JJ; Wei, D; Zhai, XD; Zhang, SY | 1 |
| Cui, K; Hao, Y; Hou, P; Li, Y; Lv, D; Shi, J; Tian, Z; Wang, M; Wang, X | 1 |
| Hu, Y; Li, AQ; Li, SS; Liu, ZY; Neely, GG; Simpson, SJ; Wang, B; Wang, QP; Zhang, RX; Zhao, XY | 1 |
| Bilmez, Y; Can, A; Kosebent, EG; Ozturk, S; Talibova, G; Tire, B | 1 |
| Li, D; Wang, R; Xie, Q; Xie, W; Ye, J; Yin, X; Zhu, Y | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Huang, B; Liu, Y; Luo, T; Meng, X; Sun, Y; Wang, J; Yu, G; Zhang, J; Zhang, R | 1 |
| Chen, F; Chen, P; Li, Y; Liu, M; Pan, Y; Wang, Q; Weng, Y; Yong, J; Zhang, G; Zhong, H | 1 |
| Chihara, R; Harada, Y; Harly, C; Kosako, H; Kubo, M; Muroi, S; Nishino, K; Nomura, A; Okuyama, K; Tanaka, H; Taniuchi, I | 1 |
| Li, YM; Luo, J; Tang, JH; Wang, J; Wang, N; Yuan, RJ | 1 |
| Che, L; Fang, Z; Feng, B; Hua, L; Jiang, X; Li, J; Lin, Y; Sun, M; Wang, Y; Xu, S; Zhuo, Y; Zou, X | 1 |
| Calamita, P; Gallo, S; Iriti, M; Kiratzis, M; Lai, G; Mancino, M; Manfrini, N | 1 |
| Choi, W; Hahn, JS; Jin, H; Kim, S; Kim, SJ; Kim, YJ; Lee, D; Lee, S; Moh, SH; Park, BG; Teoh, JY; Yoo, D | 1 |
| Arias, EB; Cartee, GD; Duan, D; Kwak, SE; Pan, X; Wang, H; Zheng, A | 1 |
| Liu, G; Lu, Q; Tian, M; Yang, A; Zhang, X | 1 |
| Cai, YY; Cao, H; Huang, P; Huang, Z; Li, Y; Lin, FC; Liu, XH; Lu, J; Wang, H; Wang, J; Wang, Q | 1 |
| Barry, ST; Cullberg, M; Eberlein, C; Miller, C; Morris, T; Sommavilla, R; Wadsworth, I | 1 |
| He, C; Lin, S; Mo, Z; Wang, P | 1 |
| Li, X; Li, Y; Tan, X; Yang, M; Zhang, X | 1 |
| Daniels, KE; Ganguly, HK; Pandey, AK; Patel, S; Sinha, SK; Yap, GPA; Zondlo, NJ | 1 |
| Liu, Y; Luo, T; Meng, X; Yu, G; Zhang, J; Zhang, R | 1 |
| Fu, S; Gu, T; He, X; Hu, X; Li, M; Mou, Y; Wang, J; Wei, J; Xiao, X; Ye, Z; You, X; Yu, Y; Zha, Y; Zhu, G | 1 |
| Carlsson, A; Emanuelsson, C; Frankel, R; Gräslund, A; Karlsson, M; Linse, S; Matus, V; Österlund, N; Thacker, D | 1 |
| Barske, T; Hagemann, M; Maček, B; Schubert, H; Spät, P; Walke, P | 1 |
| Chen, JX; Fang, QJ; Ge, HT; Liu, YL; Tu, Y; Wan, YG; Wang, DG; Wang, MZ; Wang, Y; Wu, W | 1 |
| Deng, C; He, X; Huang, X; Li, T; Lu, X; Song, J; Sun, Y; Yang, F | 1 |
| Albillos, A; Arribas, RL; Jiménez-Pompa, A; McIntosh, JM | 1 |
| Burley, GA; Chan, K; Coe, DM; Mullin, M; Queisser, MA; Sathyamurthi, PS; Shrives, H | 1 |
| Khalid, A; O'Brien-Simpson, NM; Pyreddy, S; Qazi, F; Redmond, CE; Shukla, R; Tomljenovic-Hanic, S; Verma, R | 1 |
| Chen, P; Chu, Y; Dai, Y; Ke, D; Li, L; Liu, J; Sun, X; Zhang, Z | 1 |
| Cui, H; Ji, C; Li, R; Li, W; Li, Y; Liang, M; Qin, S; Xue, J; Yang, Z; Zhang, C | 1 |
| Bai, J; Li, Y; Liu, Y; Liu, Z; Niu, F; Song, X; Yuan, S; Zhang, F; Zhang, H; Zhang, L; Zhao, C | 1 |
| Bajpai, M; Hora, S; Javed, M; Kale, P; Kashyap, M; Maras, JS; Pahwa, P; Ramakrishna, G; Rathore, A; Sarin, SK; Saxena, A; Sevak, JK; Siddiqui, H; Singh, R; Trehanpati, N; Tyagi, S; Yadav, P | 1 |
| Jeon, YJ; Kim, Y; Lee, S; Manavalan, B; Pham, NT; Phan, LT; Seo, J; Song, M | 1 |
142 review(s) available for threonine and serine
| Article | Year |
|---|---|
Fluorometric amino-acid analysis with o-phthaldialdehyde (OPA).
Topics: Aldehydes; Amino Acids; Autoanalysis; Chromatography, Ion Exchange; Enzymes; Fluorescamine; Fluorometry; Hydrogen-Ion Concentration; Hydrolysis; Isoleucine; Ninhydrin; o-Phthalaldehyde; Peptides; Proteins; Serine; Threonine; Tryptophan; Valine | 1978 |
Regulation of biodegradative threonine deaminase.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Amino Acid Sequence; Butyrates; Clostridium; Cyclic AMP; Enzyme Activation; Escherichia coli; Glucose; Hydro-Lyases; Keto Acids; Kinetics; Models, Biological; Molecular Conformation; Molecular Weight; Oxygen; Pyridoxal Phosphate; Pyruvates; Serine; Threonine; Threonine Dehydratase | 1976 |
The role of Raf-1 phosphorylation in signal transduction.
Topics: Amino Acid Sequence; Animals; Cell Division; Enzyme Activation; Growth Substances; Humans; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptors, Cell Surface; Serine; Signal Transduction; Substrate Specificity; Threonine; Tyrosine | 1992 |
Tyrosine phosphatases and their possible interplay with tyrosine kinases.
Topics: Animals; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1992 |
Dual-specificity protein kinases: will any hydroxyl do?
Topics: Amino Acid Sequence; Animals; Humans; Hydroxylation; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Serine; Substrate Specificity; Threonine; Tyrosine | 1992 |
Molecular signal integration. Interplay between serine, threonine, and tyrosine phosphorylation.
Topics: Amino Acid Sequence; Molecular Sequence Data; Phosphorylation; Protein Kinases; Serine; Signal Transduction; Threonine; Tyrosine | 1992 |
Erks: their fifteen minutes has arrived.
Topics: Amino Acid Sequence; Animals; Cell Differentiation; Cell Division; Gene Expression; Humans; Molecular Sequence Data; Phosphorylation; Protein Kinases; Sequence Alignment; Serine; Threonine | 1992 |
Serine/threonine phosphatases in the nervous system.
Topics: Animals; Humans; Nervous System; Nervous System Physiological Phenomena; Phosphoprotein Phosphatases; Protein Phosphatase 1; Serine; Threonine | 1991 |
The role of sodium ion transport in Escherichia coli energetics.
Topics: Biological Transport, Active; Carrier Proteins; Energy Metabolism; Escherichia coli; Glutamates; Hydrogen-Ion Concentration; Melibiose; Membrane Potentials; Potassium; Proline; Serine; Sodium; Sodium-Hydrogen Exchangers; Threonine | 1991 |
Glycosylation mutations of serine/threonine-linked oligosaccharides in low-density lipoprotein receptor: indispensable roles of O-glycosylation.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Cell Line; Cricetinae; Glycosylation; Humans; Molecular Sequence Data; Mutation; Oligosaccharides; Protein Processing, Post-Translational; Receptors, LDL; Serine; Threonine | 1991 |
Protein serine/threonine phosphatases; an expanding family.
Topics: Amino Acid Sequence; Animals; Biological Evolution; Cloning, Molecular; Molecular Sequence Data; Multigene Family; Phosphoprotein Phosphatases; Sequence Homology, Nucleic Acid; Serine; Threonine | 1990 |
[Insulin receptor and action mechanism of the hormone].
Topics: Animals; Insulin; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Threonine | 1989 |
[Protein kinases of the central nervous system in ontogenesis].
Topics: Aging; Animals; Brain; Calcium; Calmodulin; Humans; Nucleotides, Cyclic; Phospholipids; Protein Kinases; Protein-Tyrosine Kinases; Serine; Threonine | 1989 |
Serine phosphorylations triggered by the insulin receptor.
Topics: Animals; Enzyme Activation; Humans; Insulin; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Receptor, Insulin; Serine; Signal Transduction; Threonine | 1989 |
The structure and regulation of protein phosphatases.
Topics: Animals; Enzyme Activation; Humans; Phosphoprotein Phosphatases; Protein Conformation; Protein Processing, Post-Translational; Serine; Substrate Specificity; Threonine | 1989 |
Regulation of enzyme levels by proteolysis: the role of pest regions.
Topics: Amino Acid Sequence; Enzymes; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Proteins; Serine; Threonine | 1988 |
Protein-tyrosine kinases.
Topics: Amino Acid Sequence; Animals; Binding Sites; Epidermal Growth Factor; ErbB Receptors; Humans; Lipid Metabolism; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, Cell Surface; Retroviridae; Serine; Substrate Specificity; Threonine; Tyrosine; Viral Proteins | 1985 |
Insulin receptor kinase and its mode of signaling membrane components.
Topics: Animals; Enzyme Activation; ErbB Receptors; Humans; Insulin; Kinetics; Monosaccharide Transport Proteins; Phospholipids; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Serine; Threonine; Tyrosine | 1985 |
Synthetic N- and O-glycosyl derivatives of L-asparagine, L-serine, and L-threonine.
Topics: Asparagine; Carbohydrate Conformation; Chemical Phenomena; Chemistry; Circular Dichroism; Glycosides; Hydrolysis; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Optical Rotatory Dispersion; Serine; Structure-Activity Relationship; Threonine | 1985 |
Structure, function, and possible origin of a bifunctional allosteric enzyme, Escherichia coli aspartokinase I-homoserine dehydrogenase I.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Allosteric Regulation; Amino Acids; Antigen-Antibody Reactions; Aspartic Acid; Binding Sites; Electrophoresis, Disc; Escherichia coli; Homoserine; Kinetics; Mercaptopurine; Molecular Weight; Multienzyme Complexes; NAD; NADP; Peptide Fragments; Phosphotransferases; Protein Binding; Protein Conformation; Ribonucleotides; Serine; Spectrophotometry; Sulfhydryl Compounds; Threonine | 1974 |
Molecular evolution of glycoproteins.
Topics: Animals; Biological Evolution; Bombyx; Cell Nucleus; Chemical Phenomena; Chemistry; Chitin; DNA; Fibroins; Fungi; Galactose; Glucosamine; Glycopeptides; Glycoproteins; Glycosaminoglycans; Mannose; Molecular Biology; Oligosaccharides; Plants; RNA; Serine; Species Specificity; Threonine; Xylose | 1972 |
Cartilage proteoglycans.
Topics: Animals; Cartilage; Cartilage, Articular; Cattle; Cesium; Chondroitin; Galactose; Glycoproteins; Glycosaminoglycans; Guanidines; Hexosamines; Hexoses; Laryngeal Cartilages; Macromolecular Substances; Magnesium; Models, Chemical; Molecular Weight; Nose; Oligosaccharides; Proteins; Serine; Threonine; Xylose | 1973 |
The structure and function of gastric mucus.
Topics: Animals; Chromatography, Gel; Gastric Mucins; Gels; Humans; Methods; Molecular Weight; Mucoproteins; Proline; Protein Conformation; Serine; Solutions; Swine; Threonine; Viscosity | 1972 |
Glycoproteins.
Topics: Amino Acid Sequence; Asparagine; Carbohydrates; Cysteine; Glucosamine; Glycoproteins; Hydroxylysine; Models, Structural; Mucins; Polyribosomes; Protein Conformation; Serine; Threonine | 1972 |
A review of biochemical studies on the genetically distinct collagens of the skeletal system.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Bone and Bones; Cartilage, Articular; Collagen; Glutamates; Homoserine; Hydroxyproline; Leucine; Peptides; Phenylalanine; Proline; Rats; Serine; Threonine; Valine | 1973 |
Utilization of D- and DL- amino acids and analogs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Histidine; Isomerism; Keto Acids; Leucine; Methionine; Nutritional Requirements; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1972 |
[Metabolic control of branched-chain amino acid biosynthesis--basis reviewed from fermentative field (author's transl)].
Topics: Amino Acids; Enzyme Repression; Feedback; Fermentation; Hydro-Lyases; Isoleucine; Leucine; Serine; Serratia marcescens; Threonine; Valine | 1973 |
Regulation of serine dehydratase and phosphoglycerate dehydrogenase by proteins and essential amino acids.
Topics: Alcohol Oxidoreductases; Amino Acids; Amino Acids, Essential; Animals; Cells, Cultured; Cystine; Deficiency Diseases; Dietary Proteins; Enzyme Induction; Enzyme Repression; Glyceric Acids; Humans; L-Serine Dehydratase; Liver; Male; Methionine; Organophosphorus Compounds; Protein Biosynthesis; Rats; Serine; Threonine; Tryptophan; Valine | 1974 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Invariant features of globin primary structure and coding of their secondary structure.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Globins; Glycine; Hemoglobins; Histidine; Myoglobin; Proline; Protein Conformation; Serine; Species Specificity; Threonine; Tyrosine | 1974 |
Microbial production of amino acids.
Topics: Amino Acids; Bacteria; Biotin; Chemical Industry; Glutamates; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[Chemical cleavage of peptide bonds].
Topics: Amino Acids; Chemical Phenomena; Chemistry; Histidine; Methionine; Peptides; Proline; Serine; Threonine; Tryptophan; Tyrosine | 1968 |
[Multiplicity and specificity in code recognition of tRNA against specific amino acid].
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Cystine; Escherichia coli; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Leucine; Liver; Lysine; Phenylalanine; Rabbits; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine; Tyrosine; Yeasts | 1969 |
Selective cleavage and modification of peptides and proteins.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Glutamates; Glycine; Hydrogen-Ion Concentration; Methionine; Muramidase; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Proteins; Pyrrolidines; Ribonucleases; Serine; Succinates; Threonine; Tryptophan | 1970 |
[Deamination of threonine and serine and its allosteric regulation in microorganisms, plants and animals].
Topics: Animals; Annelida; Bacteria; Binding Sites; Chromosome Mapping; Chromosomes, Bacterial; Clostridium; Energy Transfer; Enzyme Induction; Enzyme Repression; Escherichia coli; Hydro-Lyases; Isoleucine; Liver; Plants; Plants, Edible; Rats; Rhodospirillum; Serine; Serratia marcescens; Sheep; Threonine | 1968 |
Glycoproteins.
Topics: Amino Acids; Animals; Asparagine; Carbohydrate Metabolism, Inborn Errors; Carbohydrates; Chemical Phenomena; Chemistry; Enzymes; Glycoproteins; Hydroxyproline; Kinetics; Lysine; Polysaccharides; Serine; Threonine; Transferases | 1970 |
[Synthesis of peptides by solid phase method. 1].
Topics: Arginine; Asparagine; Cysteine; Esters; Glutamine; Histidine; Lysine; Methionine; Methods; Peptides; Polystyrenes; Serine; Threonine | 1971 |
Transport of amino acids and peptides in the gut and the kidney.
Topics: Adult; Alanine; Amino Acids; Animals; Biological Transport, Active; Digestive System; Glycine; Hartnup Disease; Histidine; Humans; Hydrolysis; Intestinal Absorption; Kidney; Kidney Tubules; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Rats; Serine; Threonine; Tryptophan; Valine | 1971 |
Stereochemical aspects of pyridoxal phosphate catalysis.
Topics: 5-Aminolevulinate Synthetase; Alanine Transaminase; Allosteric Regulation; Amino Acids; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Cystathionine; Glycine; Homoserine; Kinetics; Lyases; Models, Biological; Molecular Conformation; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Schiff Bases; Serine; Structure-Activity Relationship; Threonine; Transaminases; Transferases | 1971 |
Glycosylation mutants of animal cells.
Topics: Animals; Asparagine; Carbohydrate Metabolism; Carbohydrate Sequence; Cell Line; Ceramides; Cerebrosides; Cricetinae; Glucosyltransferases; Glycolipids; Glycoproteins; Glycosphingolipids; Lectins; Mammals; Mice; Mutation; Proteins; Receptors, Mitogen; Serine; Threonine | 1984 |
[The insulin receptor: an autonomous system for membrane transmission of the hormonal message].
Topics: Adenosine Triphosphate; Animals; Cell Membrane; Insulin; Liver; Molecular Weight; Phosphorylation; Protein Kinases; Receptor, Insulin; Serine; Threonine; Tyrosine | 1984 |
Advances in amino acid metabolism in mammals.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Oxidoreductases; Amino Acids; Animals; Biological Transport; Dietary Proteins; Glutamates; Glycine; Humans; Liver; Mitochondria; Organ Specificity; Ornithine; Purine Nucleotides; Serine; Threonine; Transaminases | 1981 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
Chemical and enzymatic synthesis of glycopeptides.
Topics: Amino Acid Sequence; Carbohydrate Sequence; Endopeptidases; Glycopeptides; Glycosylation; Glycosyltransferases; Lipase; Molecular Sequence Data; Oligosaccharides; Serine; Threonine | 1995 |
Towards characterizing O-glycans: the relative merits of in vivo and in vitro approaches in seeking peptide motifs specifying O-glycosylation sites.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbohydrate Sequence; Glycopeptides; Glycoproteins; Glycosylation; Humans; Molecular Sequence Data; Molecular Structure; Polysaccharides; Serine; Threonine | 1994 |
Developments in the synthesis of glycopeptides containing glycosyl L-asparagine, L-serine, and L-threonine.
Topics: Amino Acid Sequence; Asparagine; Carbohydrate Sequence; Enzymes; Glycopeptides; Glycosylation; Molecular Sequence Data; Protein Binding; Serine; Stereoisomerism; Threonine | 1994 |
Insulin and IGF-1 signaling in oocyte maturation.
Topics: Animals; Cellular Senescence; Genes, ras; Humans; Insulin; Insulin-Like Growth Factor I; Oocytes; Phosphorylation; Serine; Signal Transduction; Threonine; Tyrosine | 1994 |
NMR, alcohols, protein solvation and protein denaturation.
Topics: Alcohols; Magnetic Resonance Spectroscopy; Protein Conformation; Protein Denaturation; Proteins; Serine; Solvents; Threonine; Tyrosine | 1994 |
Pest sequences in nuclear proteins.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Nuclear Proteins; Proline; Serine; Threonine | 1993 |
Mutagenesis studies of the cardiac Na(+)-Ca2+ exchanger.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Calcium; Carrier Proteins; Dogs; Glutamic Acid; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Serine; Sodium; Sodium-Calcium Exchanger; Structure-Activity Relationship; Threonine | 1996 |
Protein phosphatases.
Topics: Humans; Models, Molecular; Phosphoprotein Phosphatases; Phosphorylation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Serine; src Homology Domains; Substrate Specificity; Threonine; Tyrosine | 1995 |
PEST sequences and regulation by proteolysis.
Topics: Amino Acid Sequence; Glutamic Acid; Hydrolysis; Molecular Sequence Data; Proline; Proteins; Serine; Threonine | 1996 |
Protein serine/threonine phosphatases.
Topics: Amino Acid Sequence; Calcineurin; Calmodulin-Binding Proteins; Crystallography, X-Ray; Models, Molecular; Molecular Sequence Data; Phosphoprotein Phosphatases; Protein Conformation; Protein Engineering; Protein Phosphatase 1; Recombinant Proteins; Serine; Threonine | 1996 |
Regulation of potassium channels by protein kinases.
Topics: Animals; Cell Membrane; Enzyme Activation; Humans; Kinetics; Phosphorylation; Potassium Channels; Protein Kinases; Serine; Threonine; Tyrosine | 1996 |
Lysosomal glycosylasparaginase: a member of a family of amidases that employ a processed N-terminal threonine, serine or cysteine as a combined base-nucleophile catalyst.
Topics: Amidohydrolases; Amino Acid Sequence; Aspartylglucosylaminase; Cysteine; Hydrolysis; Lysosomes; Molecular Sequence Data; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; Threonine | 1996 |
The role of serine/threonine phosphorylation in hematopoietic cytokine receptor signal transduction.
Topics: Animals; Hematopoietic System; Humans; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Cytokine; Serine; Signal Transduction; Threonine | 1997 |
Phosphorylation of the proteins of the extracellular matrix of mineralized tissues by casein kinase-like activity.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Bone and Bones; Calcification, Physiologic; Casein Kinases; Collagen; Dentin; Endoplasmic Reticulum; Extracellular Matrix Proteins; Golgi Apparatus; Guanosine Triphosphate; Humans; Isoenzymes; Membrane Proteins; Molecular Sequence Data; Osteoblasts; Phosphoproteins; Phosphorylation; Protein Kinases; Serine; Skin; Tendons; Threonine; Tooth | 1997 |
Additional possible tools for identification of proteins on one- or two-dimensional electrophoresis.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Carbonic Anhydrases; Cattle; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glucagon; Humans; Mass Spectrometry; Molecular Sequence Data; Muramidase; Peptide Mapping; Proteins; Sequence Analysis; Serine; Threonine | 1998 |
The anaerobic degradation of L-serine and L-threonine in enterobacteria: networks of pathways and regulatory signals.
Topics: Anaerobiosis; Enterobacteriaceae; Escherichia coli; Genes, Bacterial; Operon; Serine; Signal Transduction; Threonine | 1998 |
[O-GlcNAc and its function].
Topics: Acetylglucosamine; Animals; Cell Nucleus; Cloning, Molecular; Diabetes Mellitus; Glycosylation; Hexosamines; Humans; N-Acetylglucosaminyltransferases; Nuclear Proteins; Phosphorylation; Serine; Signal Transduction; Threonine | 1998 |
Phosphorylation states of phospholamban.
Topics: Animals; Calcium-Binding Proteins; Calcium-Transporting ATPases; Macromolecular Substances; Models, Biological; Phosphorylation; Protein Kinases; Protein Structure, Quaternary; Serine; Threonine | 1998 |
The acceptor specificity of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases.
Topics: Animals; Catalytic Domain; Humans; N-Acetylgalactosaminyltransferases; Polypeptide N-acetylgalactosaminyltransferase; Sequence Alignment; Serine; Substrate Specificity; Threonine | 1999 |
Serine/threonine phosphorylation in cytokine signal transduction.
Topics: Animals; Cytokines; Humans; Phosphorylation; Serine; Signal Transduction; Threonine | 2000 |
Epstein-Barr virus latency: LMP2, a regulator or means for Epstein-Barr virus persistence?
Topics: Adolescent; Amino Acid Motifs; Amino Acid Sequence; Animals; B-Lymphocytes; Cell Line, Transformed; Cell Transformation, Viral; Epithelial Cells; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Mice; Mice, Transgenic; Molecular Sequence Data; Phosphorylation; Point Mutation; Proline; Protein Conformation; Protein Processing, Post-Translational; Sequence Deletion; Serine; Signal Transduction; src Homology Domains; Threonine; Tumor Virus Infections; Tyrosine; Viral Matrix Proteins; Virus Latency | 2000 |
Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade.
Topics: 14-3-3 Proteins; Animals; Cell Membrane; Enzyme Activation; Humans; MAP Kinase Signaling System; Mice; Models, Biological; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins c-raf; ras Proteins; Receptor Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Signal Transduction; Threonine; Tyrosine 3-Monooxygenase | 2001 |
Sodium-substrate cotransport in bacteria.
Topics: Amino Acid Sequence; Amino Acid Transport System X-AG; Amino Acid Transport Systems, Neutral; Amino Acids, Branched-Chain; Bacterial Proteins; Binding Sites; Carrier Proteins; Citric Acid; Cytoplasm; Escherichia coli Proteins; Glutamate Plasma Membrane Transport Proteins; Glutamates; Ion Transport; Melibiose; Molecular Sequence Data; Periplasm; Serine; Sodium; Substrate Specificity; Symporters; Threonine | 2001 |
Phosphorylation of Bcl2 and regulation of apoptosis.
Topics: Animals; Apoptosis; Humans; Leukemia; Lymphoma; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Serine; Signal Transduction; Threonine | 2001 |
Non-equilibrium proteins.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Cattle; Glutamic Acid; Humans; Macromolecular Substances; Models, Molecular; Models, Theoretical; Nitric Oxide; Prions; Proline; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Proteins; Rats; Serine; Structure-Activity Relationship; Threonine | 2001 |
The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions.
Topics: Animals; Apoptosis; Caenorhabditis elegans; Cell Division; Cell Movement; Cytoplasm; GRB7 Adaptor Protein; Humans; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Proteins; Serine; Signal Transduction; Threonine | 2001 |
Beyond the RING: CBL proteins as multivalent adapters.
Topics: Animals; Humans; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Serine; Signal Transduction; Threonine; Tissue Distribution; Ubiquitin-Protein Ligases | 2001 |
Cortactin: coupling membrane dynamics to cortical actin assembly.
Topics: Actins; Animals; Cortactin; Humans; Microfilament Proteins; Models, Biological; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Serine; Signal Transduction; Threonine; Tyrosine | 2001 |
O-glycosylation.
Topics: Antifungal Agents; Candida albicans; Endoplasmic Reticulum; Glycosylation; Golgi Apparatus; Isoenzymes; Mannose; Mannosyltransferases; Serine; Threonine; Virulence | 2001 |
Dual site phospholamban phosphorylation and its physiological relevance in the heart.
Topics: Animals; Calcium-Binding Proteins; Calcium-Transporting ATPases; Myocardial Contraction; Myocardium; Phosphorylation; Rats; Sarcoplasmic Reticulum; Serine; Threonine | 2002 |
Homogeneous glycopeptides and glycoproteins for biological investigation.
Topics: Amino Acid Sequence; Glycopeptides; Glycoproteins; Glycosylation; Glycosylphosphatidylinositols; Humans; Membrane Glycoproteins; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mucins; P-Selectin; Serine; Threonine | 2002 |
[Development of new antidiabetic drugs through the advanced knowledge of molecular biology in insulin signal transduction].
Topics: Animals; Aspirin; Drug Design; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Tyrosine Phosphatases; Receptor, Insulin; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha | 2002 |
Functional interplay between dual site phospholambam phosphorylation: insights from genetically altered mouse models.
Topics: Animals; Calcium-Binding Proteins; Heart; Mice; Mice, Knockout; Mutation; Myocardium; Phosphorylation; Serine; Threonine | 2002 |
ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer.
Topics: Aged; Alanine; Case-Control Studies; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Leucine; Linear Models; Logistic Models; Male; Middle Aged; Neoplasm Proteins; Odds Ratio; Polymorphism, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Research Design; Risk Assessment; Risk Factors; Serine; Threonine | 2003 |
[How do cells control the cadherin-mediated cell adhesion?].
Topics: alpha Catenin; Animals; beta Catenin; Binding Sites; Biological Transport; Cadherins; Catenins; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; Delta Catenin; DNA-Binding Proteins; Down-Regulation; Humans; Matrix Metalloproteinases; Phosphoproteins; Phosphorylation; Serine; Snail Family Transcription Factors; Threonine; Trans-Activators; Transcription Factors; Transcription, Genetic | 2003 |
AMINO ACID METABOLISM.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea | 1963 |
IRS-1 regulation in health and disease.
Topics: Animals; Cysteine Endopeptidases; Diabetes Mellitus, Type 2; Gene Expression Regulation; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Models, Biological; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase C; Serine; Signal Transduction; Threonine | 2003 |
Numerous posttranslational modifications provide opportunities for the intricate regulation of metabolic enzymes at multiple levels.
Topics: Arabidopsis; Cysteine; Glycosylation; Oxidation-Reduction; Phosphorylation; Plant Proteins; Plants; Protein Processing, Post-Translational; Proteomics; Serine; Thioredoxins; Threonine | 2004 |
Post-translational modifications during lantibiotic biosynthesis.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Cell Wall; Cysteine; Lanatosides; Lipid Metabolism; Molecular Sequence Data; Peptides; Protein Processing, Post-Translational; Serine; Substrate Specificity; Threonine | 2004 |
Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance.
Topics: Animals; Binding Sites; Humans; Insulin; Insulin Resistance; Models, Biological; Phosphorylation; Serine; Signal Transduction; Threonine | 2004 |
PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Motifs; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Activation; Humans; Hydrophobic and Hydrophilic Interactions; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Serine; Signal Transduction; Threonine | 2005 |
Methods in enzymology: O-glycosylation of proteins.
Topics: Animals; Biochemistry; Blotting, Western; Cell Membrane; Collagen; Dimerization; Electrophoresis, Capillary; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Glycoproteins; Glycosylation; Humans; Mass Spectrometry; Models, Chemical; Oligosaccharides; Peptides; Phosphorylation; Protein Processing, Post-Translational; Proteins; Serine; Software; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Threonine | 2005 |
Protein serine/threonine phosphatases in neuronal plasticity and disorders of learning and memory.
Topics: Animals; Brain; Humans; Learning Disabilities; Memory Disorders; Neuronal Plasticity; Phosphoprotein Phosphatases; Serine; Threonine | 2006 |
[Follicle-stimulating hormone receptor polymorphism and ovarian function].
Topics: Codon; Female; Follicle Stimulating Hormone; Gene Frequency; Humans; Infertility, Female; Ovary; Polycystic Ovary Syndrome; Polymorphism, Genetic; Receptors, FSH; Serine; Threonine | 2007 |
A newly discovered post-translational modification--the acetylation of serine and threonine residues.
Topics: Acetylation; Bacterial Proteins; Models, Biological; Phosphorylation; Protein Processing, Post-Translational; Serine; Threonine; Virulence Factors; Yersinia | 2007 |
Hexosamine biosynthesis and protein O-glycosylation: the first line of defense against stress, ischemia, and trauma.
Topics: Glycosylation; Hexosamines; Humans; Ischemia; Models, Biological; Proteins; Serine; Stress, Physiological; Threonine; Wounds and Injuries | 2008 |
Protein-O-mannosyltransferases in virulence and development.
Topics: Bacteria; Bacterial Proteins; Kinetics; Mannose; Mannosyltransferases; Phylogeny; Saccharomyces cerevisiae Proteins; Serine; Threonine; Virulence | 2008 |
c-Jun expression, activation and function in neural cell death, inflammation and repair.
Topics: Animals; Cell Death; Gene Expression; Humans; Inflammation; Models, Biological; Neurons; Proto-Oncogene Proteins c-jun; Recovery of Function; Serine; Threonine | 2008 |
[Role of O-GlcNAc modification of cellular proteins in signal transduction].
Topics: Acetylglucosamine; Glycosylation; Nuclear Proteins; Phosphorylation; Serine; Signal Transduction; Threonine; Transcription, Genetic | 2007 |
Flexible structures and ligand interactions of tandem repeats consisting of proline, glycine, asparagine, serine, and/or threonine rich oligopeptides in proteins.
Topics: Animals; Asparagine; Glycine; Humans; Ligands; Oligopeptides; Proline; Protein Conformation; Proteins; Serine; Tandem Repeat Sequences; Threonine | 2008 |
Protein O-mannosylation: conserved from bacteria to humans.
Topics: Animals; Bacterial Proteins; Endoplasmic Reticulum; Fungal Proteins; Fungi; Glycosylation; Humans; Mannose; Mannosyltransferases; Phylogeny; Polysaccharides; Protein Processing, Post-Translational; Serine; Threonine | 2009 |
Emerging roles of glucocorticoid receptor phosphorylation in modulating glucocorticoid hormone action in health and disease.
Topics: Animals; Disease; Extracellular Signal-Regulated MAP Kinases; Glucocorticoids; Glycogen Synthase Kinase 3; Health; Humans; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Glucocorticoid; Serine; Signal Transduction; Threonine | 2009 |
Ghrelin: from gene to physiological function.
Topics: Acyltransferases; Amino Acid Sequence; Animals; Gastric Mucosa; Gene Expression Regulation; Ghrelin; Growth Hormone; Humans; Molecular Sequence Data; Peptide Hormones; Protein Structure, Tertiary; Rats; Serine; Substrate Specificity; Threonine | 2010 |
Central adiposity, systemic inflammation, and the metabolic syndrome.
Topics: Abdominal Fat; Adipokines; Adiponectin; Adiposity; C-Reactive Protein; Cytokines; Diet; Humans; Inflammation; Insulin Resistance; Interleukins; Leptin; Life Style; Metabolic Syndrome; NF-kappa B; Nutritional Status; Oxidative Stress; Risk Factors; Serine; Threonine; Tumor Necrosis Factor-alpha | 2010 |
eNOS activation and NO function: structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity.
Topics: Amino Acid Sequence; Animals; Biopterins; Cell Membrane; Dimerization; Enzyme Activation; Humans; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Quaternary; Serine; Threonine; Tyrosine | 2011 |
Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling.
Topics: Humans; Models, Biological; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Protein Subunits; Serine; Signal Transduction; Threonine; Y-Box-Binding Protein 1 | 2013 |
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2.
Topics: Animals; Diabetes Mellitus; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Mice, Knockout; Mice, Transgenic; Models, Animal; Phosphorylation; Serine; Signal Transduction; Threonine | 2012 |
Divergent effects of the T1174S SCN1A mutation associated with seizures and hemiplegic migraine.
Topics: Adolescent; Adult; Cell Line, Transformed; Computer Simulation; DNA Mutational Analysis; Electric Stimulation; Female; Humans; Italy; Male; Membrane Potentials; Middle Aged; Migraine with Aura; Models, Molecular; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenotype; Seizures; Serine; Threonine; Young Adult | 2013 |
Endothelial caveolar subcellular domain regulation of endothelial nitric oxide synthase.
Topics: Animals; Caveolae; Cell Membrane; Endothelium, Vascular; Enzyme Activation; Humans; Models, Biological; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Transport; Serine; Signal Transduction; Threonine | 2013 |
Insights into the evolution of lanthipeptide biosynthesis.
Topics: Alanine; Amino Acids; Bacterial Proteins; Cyclization; Cysteine; Evolution, Molecular; Hydro-Lyases; Multienzyme Complexes; Peptides, Cyclic; Protein Processing, Post-Translational; Serine; Sulfides; Threonine | 2013 |
O-GlcNAc signaling in cancer metabolism and epigenetics.
Topics: Acetylglucosamine; Antigens, Neoplasm; Cell Proliferation; Energy Metabolism; Epigenesis, Genetic; Glycosylation; Histone Acetyltransferases; Histones; Humans; Hyaluronoglucosaminidase; N-Acetylglucosaminyltransferases; Neoplasms; Protein Processing, Post-Translational; Serine; Signal Transduction; Threonine; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 2015 |
Agents of change - concepts in Mycobacterium tuberculosis Ser/Thr/Tyr phosphosignalling.
Topics: Gene Expression Regulation, Bacterial; Mycobacterium tuberculosis; Phosphorylation; Protein Kinases; Serine; Signal Transduction; Threonine; Tyrosine | 2014 |
Acute regulation of PDK1 by a complex interplay of molecular switches.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Dimerization; Enzyme Activation; Humans; Ligands; Models, Molecular; Neoplasm Proteins; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Protein Transport; Serine; Signal Transduction; Threonine; Tyrosine | 2014 |
Serine/threonine ligation for the chemical synthesis of proteins.
Topics: Aldehydes; Amino Acid Sequence; Animals; Cyclization; Humans; Models, Molecular; Molecular Sequence Data; Peptides; Peptides, Cyclic; Proteins; Serine; Threonine | 2014 |
New chemistries for chemoselective peptide ligations and the total synthesis of proteins.
Topics: Alkynes; Amino Acid Sequence; Azides; Models, Molecular; Molecular Sequence Data; Peptides; Proline; Proteins; Serine; Threonine | 2014 |
Serine/threonine ligation for natural cyclic peptide syntheses.
Topics: Biological Products; Chemistry Techniques, Synthetic; Cyclization; Molecular Structure; Peptides, Cyclic; Serine; Threonine | 2015 |
Serine/threonine/tyrosine phosphorylation regulates DNA binding of bacterial transcriptional regulators.
Topics: Bacterial Proteins; Gene Expression Regulation, Bacterial; Histidine Kinase; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2015 |
Non-canonical Activation of Receptor Tyrosine Kinases in Cancer Progression.
Topics: Antineoplastic Agents; Cell Movement; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Phosphorylation; Receptor Protein-Tyrosine Kinases; Receptor, EphA2; Receptor, ErbB-2; Serine; Threonine | 2017 |
Chemical Approaches to Studying Labile Amino Acid Phosphorylation.
Topics: Amino Acids; Humans; Phosphorylation; Proteins; Serine; Threonine; Tyrosine | 2017 |
Biosynthetic considerations of triscatechol siderophores framed on serine and threonine macrolactone scaffolds.
Topics: Amino Acid Sequence; Catechols; Enterobactin; Lactones; Serine; Siderophores; Threonine | 2017 |
The RNA polymerase II CTD "orphan" residues: Emerging insights into the functions of Tyr-1, Thr-4, and Ser-7.
Topics: Humans; RNA Polymerase II; Serine; Threonine; Transcription, Genetic; Tyrosine | 2018 |
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Topics: Animals; beta-N-Acetylhexosaminidases; Glycoside Hydrolases; Humans; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Serine; Threonine | 2018 |
Advances, challenges and tools in characterizing bacterial serine, threonine and tyrosine kinases and phosphorylation target sites.
Topics: Animals; Bacteria; Bacterial Proteins; Humans; Phosphorylation; Protein-Tyrosine Kinases; Serine; Threonine | 2019 |
Molecular Interrogation to Crack the Case of O-GlcNAc.
Topics: Acetylglucosamine; beta-N-Acetylhexosaminidases; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Serine; Threonine | 2020 |
Importance of protein Ser/Thr/Tyr phosphorylation for bacterial pathogenesis.
Topics: Animals; Bacteria; Bacterial Infections; Bacterial Proteins; Humans; Phosphoproteins; Phosphorylation; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2020 |
Controlling Ser/Thr protein phosphatase PP1 activity and function through interaction with regulatory subunits.
Topics: Animals; Humans; Protein Phosphatase 1; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine | 2020 |
Evolutionary crossroads of cell signaling: PP1 and PP2A substrate sites in intrinsically disordered regions.
Topics: Animals; Binding Sites; Evolution, Molecular; Humans; Intrinsically Disordered Proteins; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; Serine; Signal Transduction; Substrate Specificity; Threonine | 2021 |
Advances in Strategies and Tools Available for Interrogation of Protein O-GlcNAcylation.
Topics: Acetylglucosamine; Humans; Molecular Conformation; Protein Processing, Post-Translational; Proteins; Serine; Threonine | 2021 |
Diversity in Serine/Threonine Protein Kinase-4 Deficiency and Review of the Literature.
Topics: Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Intracellular Signaling Peptides and Proteins; Lymphopenia; Protein Serine-Threonine Kinases; Serine; Threonine | 2021 |
Fine-Tuning of Platelet Responses by Serine/Threonine Protein Kinases and Phosphatases-Just the Beginning.
Topics: Animals; Blood Platelets; Humans; Mice; Mitogen-Activated Protein Kinases; Models, Animal; Myosin Light Chains; Phosphoprotein Phosphatases; Platelet Activation; Protein Kinases; Proteomics; Serine; Signal Transduction; Syk Kinase; Threonine | 2021 |
[Advancesin enrichment and detection methods for
Topics: Arginine; Histidine; Lysine; Phosphorylation; Proteins; Serine; Threonine; Tyrosine | 2020 |
Serine-threonine protein phosphatase regulation of Cx43 dephosphorylation in arrhythmogenic disorders.
Topics: Cell Communication; Connexin 43; Gap Junctions; Phosphoprotein Phosphatases; Phosphorylation; Serine; Threonine | 2021 |
Serine/threonine kinase inhibition as antifibrotic therapy: transforming growth factor-β and Rho kinase inhibitors.
Topics: Fibrosis; Humans; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases; Serine; Threonine; Transforming Growth Factor beta; Transforming Growth Factors | 2022 |
Complex cyclic peptide synthesis via serine/threonine ligation chemistry.
Topics: Chemistry Techniques, Synthetic; Cyclization; Molecular Structure; Peptides, Cyclic; Serine; Threonine | 2021 |
Recent advances in bacterial signaling by serine/threonine protein kinases.
Topics: Bacteria; Bacterial Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine | 2022 |
Orchestrating serine/threonine phosphorylation and elucidating downstream effects by short linear motifs.
Topics: Binding Sites; Humans; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Serine; Substrate Specificity; Threonine | 2022 |
The NEK family of serine/threonine kinases as a biomarker for cancer.
Topics: Biomarkers; Cell Cycle Proteins; Humans; Neoplasms; NIMA-Related Kinases; Protein Serine-Threonine Kinases; Serine; Threonine | 2023 |
Protein Tyrosine and Serine/Threonine Phosphorylation in Oral Bacterial Dysbiosis and Bacteria-Host Interaction.
Topics: Dental Caries; Dysbiosis; Host Microbial Interactions; Humans; Microbiota; Phosphorylation; Porphyromonas gingivalis; Serine; Threonine; Tyrosine | 2021 |
Importance of Tyrosine Phosphorylation in Hormone-Regulated Plant Growth and Development.
Topics: Animals; Biological Phenomena; Hormones; Phosphorylation; Plant Development; Plant Growth Regulators; Plants; Protein Processing, Post-Translational; Serine; Threonine; Tyrosine | 2022 |
Microtubule-affinity regulating kinase 4: A potential drug target for cancer therapy.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Humans; Microtubules; Neoplasms; Neurodegenerative Diseases; NF-kappa B; Phosphates; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Serine; Threonine; TOR Serine-Threonine Kinases; Tyrosine | 2022 |
Protein O-GlcNAcylation and the regulation of energy homeostasis: lessons from knock-out mouse models.
Topics: Acetylglucosamine; Animals; Glucose; Homeostasis; Mice; Mice, Knockout; N-Acetylglucosaminyltransferases; Proteins; Serine; Threonine; Uridine Diphosphate | 2022 |
Recent advances in demystifying O-glycosylation in health and disease.
Topics: Glycopeptides; Glycoproteins; Glycosylation; Polysaccharides; Serine; Threonine | 2022 |
A patent and literature review of CDK12 inhibitors.
Topics: Animals; Cyclin-Dependent Kinases; Cyclins; Humans; Mice; Myotonic Dystrophy; Neoplasms; Patents as Topic; Protein Kinase Inhibitors; RNA, Messenger; Serine; Threonine | 2022 |
An update regarding the role of WNK kinases in cancer.
Topics: Alanine; Animals; Bicarbonates; Mammals; Neoplasms; Neovascularization, Pathologic; Proline; Serine; Sodium Chloride Symporters; Threonine | 2022 |
ZBP1: A Powerful Innate Immune Sensor and Double-Edged Sword in Host Immunity.
Topics: DNA, Z-Form; Immunity, Innate; Interferon Regulatory Factor-3; Interferon Type I; NF-kappa B; Nucleic Acids; RNA; RNA-Binding Proteins; Serine; Threonine | 2022 |
Cdk5-p25 as a key element linking amyloid and tau pathologies in Alzheimer's disease: Mechanisms and possible therapeutic interventions.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Calpain; Cyclin-Dependent Kinase 5; Humans; Phosphorylation; Serine; tau Proteins; Threonine | 2022 |
Emerging insights into serine/threonine-specific phosphoprotein phosphatase function and selectivity.
Topics: Holoenzymes; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Phosphatase 2; Serine; Threonine | 2022 |
Mechanisms of TNF-independent RIPK3-mediated cell death.
Topics: Apoptosis; Cell Death; Humans; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Threonine; Toll-Like Receptor 3 | 2022 |
RIPK1 and RIPK3 inhibitors: potential weapons against inflammation to treat diabetic complications.
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Humans; Inflammation; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Threonine | 2023 |
6 trial(s) available for threonine and serine
| Article | Year |
|---|---|
[Controlled clinical study and clinico-psychological evaluation of a preparation with neurotrophic effects].
Topics: Aged; Arginine; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Glutamine; Humans; Male; Mental Disorders; Middle Aged; Nervous System Diseases; Organophosphorus Compounds; Serine; Threonine; Tryptophan; Vitamin B 12 | 1977 |
Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity.
Topics: Adult; Aged; Alanine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arginine; Asparagine; Aspartic Acid; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Excitatory Amino Acids; Female; Fluoxetine; Glycine; Histidine; Humans; Male; Middle Aged; Personality Inventory; Pindolol; Prognosis; Selective Serotonin Reuptake Inhibitors; Serine; Taurine; Threonine; Trazodone; Treatment Outcome | 1998 |
Subthalamic nucleus stimulation is efficacious in patients with Parkinsonism and LRRK2 mutations.
Topics: Adult; Aged; Deep Brain Stimulation; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Retrospective Studies; Serine; Subthalamic Nucleus; Threonine | 2007 |
SIRT1, AMP-activated protein kinase phosphorylation and downstream kinases in response to a single bout of sprint exercise: influence of glucose ingestion.
Topics: Acetyl-CoA Carboxylase; Adult; AMP-Activated Protein Kinases; Bicycling; Biomarkers; Biopsy; Blood Glucose; Exercise; Glucose; GTPase-Activating Proteins; Heat-Shock Proteins; Humans; Insulin; Lactic Acid; Male; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Proto-Oncogene Proteins c-akt; Quadriceps Muscle; Recovery of Function; Serine; Signal Transduction; Sirtuin 1; Threonine; Time Factors; Transcription Factors; Young Adult | 2010 |
Preexercise aminoacidemia and muscle protein synthesis after resistance exercise.
Topics: Acidosis; Adult; Amino Acids; Humans; Leg; Leucine; Male; Milk Proteins; Muscle Proteins; Muscle, Skeletal; Phosphorylation; Resistance Training; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Sweetening Agents; Threonine; Whey Proteins | 2012 |
Radiomics features based on MRI predict BRAF V600E mutation in pediatric low-grade gliomas: A non-invasive method for molecular diagnosis.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Magnetic Resonance Imaging; Male; Mutation; Proto-Oncogene Proteins B-raf; Retrospective Studies; Serine; Threonine | 2022 |
2930 other study(ies) available for threonine and serine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Circularly polarized emission studies on Tb3+ and Eu3+ complexes with potentially terdentate amino acids in aqueous solution.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Circular Dichroism; Europium; Histidine; Hydrogen-Ion Concentration; Serine; Terbium; Threonine | 1977 |
Purification and properties of an endo-alpha-N-acetyl-D-galactosaminidase from Diplococcus pneumoniae.
Topics: Acetylglucosaminidase; Glycoproteins; Hexosaminidases; Kinetics; Serine; Streptococcus pneumoniae; Substrate Specificity; Threonine | 1977 |
The phosphorylation of ribosomal proteins L14 and S3 in Krebs II ascites cells.
Topics: Cells, Cultured; Culture Media; Glucose; Glycolysis; Hydrogen-Ion Concentration; Phosphates; Phosphoproteins; Ribosomal Proteins; Serine; Threonine | 1978 |
A D-serine dehydratase acting also on L-serine from Klebsiella pneumoniae.
Topics: Enzyme Induction; Hydrogen-Ion Concentration; Kinetics; Klebsiella pneumoniae; L-Serine Dehydratase; Molecular Weight; Serine; Stereoisomerism; Substrate Specificity; Threonine | 1978 |
Phosphorylation of Isocitrate dehydrogenase of Escherichia coli.
Topics: Acetates; Escherichia coli; Isocitrate Dehydrogenase; NADP; Phosphorylation; Protein Kinases; Serine; Threonine | 1979 |
The destruction of serine and threonine thiohydantoins during the sequence determination of peptides by 4-N,N-dimethylaminoazobenzene 4'-isothiocyanate.
Topics: Amino Acid Sequence; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Hydantoins; Hydrogen-Ion Concentration; Oxygen; p-Dimethylaminoazobenzene; Peptides; Serine; Spectrophotometry, Ultraviolet; Thiocyanates; Thiohydantoins; Threonine | 1979 |
Phosphorylation and nucleic acid binding properties of m1 Moloney murine sarcoma virus-specific pP60gag.
Topics: DNA; DNA, Single-Stranded; Epitopes; Gammaretrovirus; Leukemia Virus, Feline; Phosphoproteins; Phosphorus; Protein Binding; RNA; Sarcoma Viruses, Murine; Serine; Threonine; Viral Proteins | 1977 |
Ribosomal proteins in growing and starved Tetrahymena pyriformis. Starvation-induced phosphorylation of ribosomal proteins.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Organophosphorus Compounds; Phosphoproteins; Phosphorylation; Ribosomal Proteins; Ribosomes; Serine; Tetrahymena pyriformis; Threonine | 1978 |
Identification of organic phosphorus covalently bound to collagen and non-collagenous proteins of chicken-bone matrix. The presence of O-phosphoserine and O-phosphothreonine in non-collagenous proteins, and their absence from phosporylated collagen.
Topics: 1-Carboxyglutamic Acid; Amino Acids; Animals; Bone and Bones; Chemical Phenomena; Chemistry; Chickens; Collagen; Edetic Acid; Organophosphorus Compounds; Phosphopeptides; Phosphoproteins; Serine; Threonine | 1979 |
Identification of phosphopeptides and gamma-carboxyglutamic acid-containing peptides in epiphyseal growth plate cartilage.
Topics: 1-Carboxyglutamic Acid; Animals; Animals, Newborn; Bone and Bones; Cartilage; Cattle; Glutamates; Molecular Weight; Peptides; Phosphoproteins; Serine; Threonine | 1979 |
Phosphopeptides and gamma-carboxyglutamic acid-containing peptides in calcified turkey tendon: their absence in uncalcified tendon.
Topics: 1-Carboxyglutamic Acid; Aging; Animals; Female; Glutamates; Organophosphorus Compounds; Peptides; Phosphopeptides; Serine; Tendons; Threonine; Turkeys | 1979 |
Identification of O-phosphoserine, O-phosphothreonine and gamma-carboxyglutamic acid in the non-collagenous proteins of bovine cementum; comparison with dentin, enamel and bone.
Topics: 1-Carboxyglutamic Acid; Amino Acids; Animals; Cattle; Dental Cementum; Dental Enamel; Dentin; Fetus; Glutamates; Male; Phosphoserine; Phosphothreonine; Serine; Threonine | 1979 |
[Protein kinase activity in Escherichia coli].
Topics: Bacterial Proteins; Escherichia coli; Protein Kinases; Ribosomal Proteins; Serine; Threonine | 1979 |
[A simple method for detecting phosphoserine and phosphothreonine in proteins (author's transl)].
Topics: Animals; Brain; Chick Embryo; Electrophoresis, Paper; Histones; Liver; Phosphoserine; Phosphothreonine; Protein Hydrolysates; Ribosomal Proteins; Ribosomes; Serine; Threonine | 1979 |
Alkaline borohydride treatment of cartilage keratan sulfate: a comparison of two reaction conditions.
Topics: Alanine; Animals; Cattle; Chromatography, Ion Exchange; Evaluation Studies as Topic; Galactosamine; Glucosamine; Glycosaminoglycans; Keratan Sulfate; Methods; Nasal Septum; Papain; Serine; Threonine | 1975 |
The nature of the protein moieties of cartilage proteoglycans of pig and ox.
Topics: Amino Acids; Amino Sugars; Animals; Carbohydrates; Cattle; Glycosaminoglycans; Hyaluronoglucosaminidase; Laryngeal Cartilages; Nasal Septum; Proteins; Proteoglycans; Serine; Swine; Threonine; Uronic Acids | 1975 |
[Influence of intestinal microflora on the amino acid composition of lamb feces].
Topics: Amino Acids; Animals; Bacterial Proteins; Body Weight; Feces; Germ-Free Life; Lysine; Male; Nitrogen; Proteins; Serine; Sheep; Threonine | 1976 |
A simple and practical method for isolation of an early plasmin degradation product of human fibrinogen.
Topics: Electrophoresis, Polyacrylamide Gel; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Glycine; Humans; Immunodiffusion; Methods; Molecular Weight; Proline; Serine; Threonine | 1977 |
Adenosine 3'5'-m onophosphate dependent phosphorylation of ribosomes and ribosomal subunits from bovine corpus luteum.
Topics: Animals; Cattle; Centrifugation, Density Gradient; Corpus Luteum; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Female; Luteinizing Hormone; Organophosphorus Compounds; Phosphoproteins; Protein Kinases; Ribosomal Proteins; Ribosomes; Serine; Threonine | 1975 |
Comparative studies on the structural phosphoproteins of mammalian type C viruses.
Topics: Animals; Cats; Chemical Fractionation; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hominidae; Mice; Molecular Weight; Papio; Peptides; Phosphoproteins; Rats; Retroviridae; Serine; Threonine; Viral Proteins; Virus Cultivation | 1975 |
Protein phosphorylation and metabolic control.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Calcium; Cyclic AMP; Glycogen; Models, Biological; Muscles; Phosphoproteins; Phosphorylase Kinase; Phosphorylase Phosphatase; Phosphorylases; Phosphotransferases; Proteins; Serine; Threonine | 1975 |
N-terminal amino acid sequences in the major capsid proteins of foot-and-mouth disease virus types A, O, and C.
Topics: Amino Acid Sequence; Amino Acids; Aphthovirus; Asparagine; Aspartic Acid; Dansyl Compounds; Glycine; Leucyl Aminopeptidase; Serine; Serotyping; Threonine; Viral Proteins | 1975 |
Biochemical study of cardiac valvular tissue. The isolation of glycoproteins and proteoglycans from salt-insoluble materials of bovine heart valve.
Topics: Amino Acids; Animals; Cattle; Fucose; Galactose; Glucose; Glycoproteins; Glycosaminoglycans; Heart Valves; Hexosamines; Mannose; Microbial Collagenase; Molecular Weight; Proteins; Proteoglycans; Serine; Sialic Acids; Threonine; Urea; Uronic Acids | 1975 |
The isolation and characterization of glycopeptides and mucopolysaccharides from plasma membranes of an ascites hepatoma, AH 130.
Topics: Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Membrane; Female; Glycopeptides; Glycosaminoglycans; Heparitin Sulfate; Hexosamines; Hexoses; Liver Neoplasms; Rats; Serine; Sialic Acids; Sulfuric Acid Esters; Threonine | 1975 |
Preferential dephosphorylation of protein bound phosphorylthreonine and phosphorylserine residues by cytosol and mitochondrial "casein phosphatases".
Topics: Animals; Caseins; Cytosol; Liver; Mitochondria, Liver; Phosphoric Monoester Hydrolases; Proteins; Rats; Serine; Threonine | 1976 |
Formation of amino acids by cobalt-60 irradiation of hydrogen cyanide solutions.
Topics: Alanine; Amino Acids; Aspartic Acid; Cobalt Radioisotopes; Glutamates; Glycine; Hydrogen Cyanide; Hydrolysis; Serine; Threonine; Valine | 1976 |
Phosphorylation of endogenous membrane proteins by endogenous protein kinase at the outer surface of Ehrlich cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bucladesine; Carcinoma, Ehrlich Tumor; Cell Membrane; Cells, Cultured; Cyclic AMP; Male; Mice; Neoplasm Proteins; Phosvitin; Protein Binding; Protein Kinases; Serine; Threonine | 1976 |
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.
Topics: Arginine; Cyclic AMP; Kinetics; Oligopeptides; Phosphorylases; Protein Kinases; Serine; Structure-Activity Relationship; Threonine | 1977 |
The role of carbohydrate in the glycoenzyme invertase of Neurospora crassa.
Topics: Amino Acids; Carbohydrates; Glycosides; Neurospora; Neurospora crassa; Periodic Acid; Pronase; Protein Conformation; Serine; Sucrase; Threonine | 1977 |
A specific method for the determination of threonine in rat blood plasma using aldehyde dehydrogenase.
Topics: Aldehyde Oxidoreductases; Animals; Glucose; Periodic Acid; Rats; Serine; Spectrometry, Fluorescence; Threonine | 1977 |
The synthesis of Sendai virus polypeptides in infected cells. III. Phosphorylation of polypeptides.
Topics: Capsid; Cell Line; Membrane Proteins; Parainfluenza Virus 1, Human; Phosphopeptides; Protein Kinases; Serine; Threonine; Viral Proteins | 1977 |
Casein phosphatase dependent dephosphorylation of 32P-casein fractions labelled by two protein kinases.
Topics: Animals; Caseins; Cytosol; Liver; Phosphoprotein Phosphatases; Protein Kinases; Rats; Serine; Threonine | 1977 |
Phosphorylation of an actin.tropomyosin.troponin complex from human skeletal muscle.
Topics: Actins; Actomyosin; Adenosine Triphosphatases; Adenosine Triphosphate; Calcium; Cyclic AMP; Humans; In Vitro Techniques; Magnesium; Muscle Proteins; Muscles; Phosphates; Protein Kinases; Serine; Threonine; Tropomyosin; Troponin | 1977 |
The substrate specificity of cyclic AMP-dependent protein kinase: amino acid sequences at the phosphorylation sites of herring protamine (clupeine).
Topics: Amino Acid Sequence; Animals; Clupeine; Cyclic AMP; Fishes; Peptide Fragments; Protamines; Protein Kinases; Serine; Substrate Specificity; Threonine | 1978 |
The structure of polymyxin S. (Studies on antibiotics from the genus Bacillus. XXI).
Topics: Amino Acid Sequence; Aminobutyrates; Chemical Phenomena; Chemistry; Phenylalanine; Polymyxins; Serine; Threonine | 1977 |
On the structural similarity of ApoA-I and ApoA-II of human high density lipoproteins.
Topics: Amino Acid Sequence; Apolipoproteins; Biological Evolution; Codon; Humans; Lipoproteins, HDL; Serine; Structure-Activity Relationship; Threonine | 1978 |
Phosphorylation of calf thymus RNA polymerase II by nuclear cyclic 3',5'-AMP-independent protein kinase.
Topics: Adenylyl Imidodiphosphate; Animals; Cattle; Cell Nucleus; Cyclic AMP; DNA-Directed RNA Polymerases; Enzyme Activation; Phosphates; Protein Kinases; RNA Polymerase II; Serine; Threonine; Thymus Gland | 1978 |
Multiple forms of cytosol and membrane-bound protein kinase activity in human erythrocytes.
Topics: Caseins; Cyclic AMP; Cytosol; Erythrocyte Membrane; Erythrocytes; Humans; Protamine Kinase; Protein Kinases; Serine; Sodium Chloride; Threonine | 1978 |
Cyclic nucleotide-independent protein kinases from rabbit reticulocytes. Site-specific phosphorylation of casein variants.
Topics: Amino Acid Sequence; Amino Acids; Animals; Caseins; Chymotrypsin; Cyclic AMP; Peptide Fragments; Phosphorylation; Protein Kinases; Rabbits; Reticulocytes; Serine; Substrate Specificity; Threonine | 1979 |
Phosphorylation of threonine and serine residues of native and partially dephosphorylated caseins by a rat liver cyclic AMP-insensitive protein kinase.
Topics: Animals; Caseins; Cyclic AMP; Kinetics; Liver; Phosphorylation; Protein Kinases; Rats; Serine; Threonine | 1979 |
Glycine metabolism by Pseudomonas aeruginosa: hydrogen cyanide biosynthesis.
Topics: Carbon Radioisotopes; Glycine; Hydrogen Cyanide; Methionine; Pseudomonas aeruginosa; Serine; Threonine | 1977 |
Characterization of a protein kinase and two phosphate acceptor proteins from vaccinia virions.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acids; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kinetics; Magnesium; Peptide Fragments; Protamines; Protein Kinases; Serine; Structure-Activity Relationship; Threonine; Time Factors; Trypsin; Vaccinia virus; Viral Proteins | 1975 |
Bovine brain adenosine 3',5'-monophosphate dependent protein kinase. Mechanism of regulatory subunit inhibition of the catalytic subunit.
Topics: Animals; Brain; Cattle; Cyclic AMP; Enzyme Activation; Ethyl Ethers; Formates; Hydrogen-Ion Concentration; Kinetics; Protein Binding; Protein Kinases; Serine; Threonine | 1975 |
The isolation and partial characterization of the major bronchial glycoproteins.
Topics: Acetylgalactosamine; Acetylglucosamine; Amino Acids; Blood Group Antigens; Bronchi; Carbohydrates; Fucose; Galactose; Gastric Mucosa; Glycoproteins; Humans; Molecular Conformation; Mucous Membrane; Serine; Sputum; Threonine | 1978 |
Role of transport systems in amino acid metabolism: leucine toxicity and the branched-chain amino acid transport systems.
Topics: Biological Transport, Active; Escherichia coli; Genes; Isoleucine; Leucine; Mutation; Serine; Threonine; Threonine Dehydratase; Valine | 1977 |
Alteration of free serum amino acids in voles infected with Trypanosoma brucei gambiense.
Topics: Alanine; Amino Acids; Animals; Arvicolinae; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Male; Proline; Serine; Threonine; Trypanosomiasis, African; Tryptophan; Tyrosine; Valine | 1977 |
Threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. Kinetic and spectroscopic effects upon binding of serine and threonine.
Topics: Aspartokinase Homoserine Dehydrogenase; Binding Sites; Escherichia coli; Kinetics; Multienzyme Complexes; Protein Binding; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Threonine | 1977 |
Structure-function relationship in Escherichia coli initiation factors. I. Phosphorylation of IF-3 by coliphage T7 protein kinase.
Topics: Amino Acid Sequence; Coliphages; Escherichia coli; Kinetics; Peptide Initiation Factors; Phosphopeptides; Protein Binding; Protein Conformation; Protein Kinases; Ribosomes; Serine; Structure-Activity Relationship; Threonine | 1977 |
Multivalent induction of biodegradative threonine deaminase.
Topics: Amino Acids; Arginine; Aspartic Acid; Chloramphenicol; Enzyme Induction; Escherichia coli; Leucine; Methionine; Rifampin; Serine; Threonine; Threonine Dehydratase; Valine | 1977 |
Growth and amino acid requirements of various strains of group B streptococci.
Topics: Aerobiosis; Amino Acids; Anaerobiosis; Culture Media; Glucose; Glycine; Phosphates; Serine; Species Specificity; Streptococcus agalactiae; Threonine | 1978 |
[Identification of 2 phosphorylated amino acids in chicken bone phosphoproteins].
Topics: Animals; Bone and Bones; Chickens; Organophosphates; Phosphoproteins; Serine; Threonine | 1977 |
On the biosynthesis of 5-methoxyuridine and uridine-5-oxyacetic acid in specific procaryotic transfer RNAs.
Topics: Alanine; Bacillus subtilis; Escherichia coli; Oligoribonucleotides; RNA, Transfer; S-Adenosylmethionine; Serine; Threonine; Uridine; Valine | 1978 |
Side reactions in peptide synthesis. X. Prevention of O-acylation during coupling with active esters.
Topics: Acylation; Amino Acid Sequence; Dinitrophenols; Esters; Pentachlorophenol; Peptides; Serine; Threonine; Tyrosine | 1979 |
Some observations on why many proteins are glycosylated.
Topics: Asparagine; Glycoproteins; Glycosides; Hemoglobin A; Humans; Proteoglycans; Serine; Threonine | 1979 |
Species-specific variations in H1 histone phosphopeptides.
Topics: Animals; Cell Line; Cricetinae; Histones; Humans; Mice; Organophosphorus Compounds; Peptide Fragments; Phosphorylation; Rats; Serine; Species Specificity; Threonine; Trypsin | 1979 |
[Senile liver and its repercussions on cerebral activity].
Topics: Aged; Aging; Amino Acids; Brain; Cystine; Glutamates; Histidine; Humans; Liver; Serine; Threonine; Tyrosine | 1979 |
Inactivation of DNase by 2-nitro-5-thiocyanobenzoic acid. II. Serine and threonine are the sites of reaction on the DNase molecule.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cattle; Deoxyribonucleases; Peptide Fragments; Protein Binding; Serine; Threonine | 1979 |
Hydroxy amino acid metabolism in Pseudomonas cepacia: role of L-serine deaminase in dissimilation of serine, glycine, and threonine.
Topics: Amino Acid Oxidoreductases; Enzyme Induction; Glycine; L-Serine Dehydratase; Mutation; Pseudomonas; Serine; Threonine | 1979 |
[Free amino acids in calf embryos].
Topics: Alanine; Amino Acids; Animals; Cattle; Embryo, Mammalian; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1979 |
Specific sulfonation of tyrosine, tryptophan and hydroxy-amino acids in peptides.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Peptides; Protein Binding; Serine; Sulfonic Acids; Sulfuric Acids; Threonine; Tryptophan; Tyrosine | 1979 |
Formic acid-induced modification of hydroxy amino acids to other amino acids.
Topics: Chemical Phenomena; Chemistry; Formates; Serine; Threonine | 1979 |
[Normal range of free amino acids in cerebrospinal fluid of children (author's transl)].
Topics: Adolescent; Age Factors; Amino Acids; Aspartic Acid; Child; Child, Preschool; Citrulline; Female; Histidine; Humans; Infant; Lysine; Male; Methods; Serine; Sex Factors; Threonine; Tyrosine | 1977 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: effect of dietary protein.
Topics: Adult; Aged; Amino Acids; Circadian Rhythm; Dietary Proteins; Hepatic Encephalopathy; Humans; Isoleucine; Leucine; Liver Cirrhosis, Alcoholic; Male; Methionine; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Quantitation of the beta-elimination reaction as used on glycoproteins.
Topics: Alanine; Amino Acids; Borohydrides; Butyrates; Chemistry, Organic; Galactosamine; Glucosamine; Glycoproteins; Hexosamines; Organic Chemistry Phenomena; Serine; Serum Albumin; Threonine | 1977 |
Analyses of phosphorylated tryptic peptide of spectrin from human erythrocyte membrane.
Topics: Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Membrane Proteins; Peptide Fragments; Peptides; Phosphates; Protein Kinases; Serine; Spectrin; Threonine; Trypsin | 1977 |
Empirical calculations on cyclic dipeptides. Conformations of serine, threonine and histidine residues.
Topics: Histidine; Models, Structural; Peptides, Cyclic; Protein Conformation; Serine; Threonine | 1978 |
The identification of O-phosphothreonine in the soluble non-collagenous phosphoproteins of bone matrix.
Topics: Animals; Bone and Bones; Cattle; Chickens; Humans; Male; Organophosphorus Compounds; Phosphoproteins; Rabbits; Rats; Serine; Sheep; Species Specificity; Swine; Threonine; Turkeys | 1978 |
Identification of a protein kinase activity associated with human adenoviruses.
Topics: Adenoviruses, Human; Dialysis; Osmolar Concentration; Peptides; Phosphates; Protein Kinases; Serine; Threonine; Viral Proteins; Virion | 1978 |
Phosphoproteins of adenovirus 2.
Topics: Adenoviruses, Human; HeLa Cells; Molecular Weight; Peptides; Phosphoproteins; Serine; Threonine; Viral Proteins | 1978 |
Methods for the assessment of nonhistone phosphorylation (acid-stable, alkali-labile linkages).
Topics: Chromatography, Ion Exchange; Chromosomal Proteins, Non-Histone; Electrophoresis, Polyacrylamide Gel; Methods; Phosphorylation; Serine; Threonine | 1978 |
Evidence for strictly Na+-dependent accumulation of serine and threonine in brain cortical synaptosomes from newborn rats.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Kinetics; Rats; Serine; Sodium; Synaptosomes; Threonine | 1978 |
Phosphoryl group transfer from Ehrlich cells prelabeled in vivo with (32P)-orthophosphate and (14C)-glucose to unlabeled glioma cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Cells, Cultured; Glioma; Glucose; Leucine; Male; Mice; Neuroglia; Phosphates; Phosphorylation; Serine; Threonine | 1978 |
Interrelated changes of amino acids in the retina and optic tectum of a marine fish with alterations of illuminating conditions.
Topics: Amino Acids; Animals; Aspartic Acid; Dark Adaptation; Fishes; gamma-Aminobutyric Acid; Glutamates; Glycine; Photic Stimulation; Retina; Serine; Superior Colliculi; Taurine; Threonine | 1978 |
Chemical characterization of new antibiotics, cerexins A and B. (Studies on antibiotics from the genus Bacillus. II)
Topics: Anti-Bacterial Agents; Aspartic Acid; Bacillus cereus; Fatty Acids; Hydrolysis; Hydroxylysine; Leucine; Peptides; Serine; Threonine; Tryptophan; Valine | 1975 |
The variability of human lambda-chain constant regions and some relationships to V-regions sequences.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Chromatography, Ion Exchange; Cystine; Electrophoresis, Paper; Glutamates; Glycine; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Isoleucine; Leucine; Peptides; Proline; Serine; Thiazoles; Threonine; Valine | 1976 |
[The serine- and threonine dehydratases of brucellae].
Topics: Ammonia; Brucella; Brucella abortus; Catalysis; Hydro-Lyases; L-Serine Dehydratase; Serine; Species Specificity; Threonine; Threonine Dehydratase | 1976 |
Variations in the concentrations of blood plasma free amino acids in suckled and fasted neonatal pigs.
Topics: Amino Acids; Animals; Animals, Newborn; Arginine; Cystine; Fasting; Glycine; Leucine; Lysine; Proline; Serine; Swine; Threonine; Tyrosine | 1977 |
Protection of aspartic acid, serine, and threonine in solid-phase peptide synthesis.
Topics: Aspartic Acid; Bromobenzenes; Peptides; Serine; Threonine | 1977 |
Serine transhydroxymethylase: evidence for a sequential random mechanism.
Topics: Animals; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Liver; Rabbits; Serine; Spectrophotometry; Threonine; Transferases | 1977 |
Reactions of polyfunctional amino acids with N,N'-carbonyldiimidazole in aqueous solution--oligopeptide formation.
Topics: Amino Acids; Dipeptides; Electrophoresis, Paper; Histidine; Imidazoles; Indicators and Reagents; Methods; Oligopeptides; Serine; Threonine | 1977 |
Ovine submaxillary mucin. Primary structure and peptide substrates of UDP-N-acetylgalactosamine:mucin transferase.
Topics: Amino Acid Sequence; Amino Acids; Animals; Galactosyltransferases; Mucins; Peptide Fragments; Serine; Sheep; Submandibular Gland; Threonine; Trypsin; Uridine Diphosphate N-Acetylglucosamine | 1977 |
Complete analysis of protein hydrolysates containing phosphoserine and phosphothreonine using the amino acid analyzer.
Topics: Amino Acids; Autoanalysis; Cysteic Acid; Organophosphorus Compounds; Serine; Threonine | 1977 |
The covalent linkage of protein to carbohydrate in the extracellular protein-polysaccharide from the red alga Porphyridium cruentum.
Topics: Amino Acids; Centrifugation, Isopycnic; Extracellular Space; Protein Binding; Proteoglycans; Rhodophyta; Serine; Threonine; Xylose | 1977 |
Acidic phosphoproteins of the 60-S ribosomal subunits from HeLa cells.
Topics: Electrophoresis, Polyacrylamide Gel; HeLa Cells; Isoelectric Point; Molecular Weight; Phosphates; Phosphoproteins; Protein Kinases; Ribosomal Proteins; Serine; Threonine | 1977 |
Amino terminal sequence and location of phosphate groups of the major human casein.
Topics: Amino Acid Sequence; Amino Acids; Animals; Caseins; Cattle; Chemical Phenomena; Chemistry; Female; Humans; Milk, Human; Organophosphorus Compounds; Pregnancy; Serine; Species Specificity; Threonine | 1976 |
Phosphoproteins of the cell surface as generated by endogenous or exogenous protein kinase: stability of the 32P-labelled product.
Topics: Cell Line; Cell Membrane; Deoxyribonucleases; HeLa Cells; Phosphoproteins; Pronase; Protein Kinases; Ribonucleases; Serine; Threonine | 1976 |
Urinary amino acid excretion in acute leukemia.
Topics: Amino Acids; Antineoplastic Agents; Aspartic Acid; Female; Humans; Leukemia; Male; Remission, Spontaneous; Renal Aminoacidurias; Serine; Threonine | 1976 |
Serine and threonine ethanolamine phosphate diesters, and some other unusual compounds in the lens of the cod fish (Gadus morhua) and haddock (Gadus aeglefinus).
Topics: Animals; Electrophoresis; Ethanolamines; Fishes; Histidine; Lens, Crystalline; Organophosphorus Compounds; Phosphothreonine; Riboflavin; Serine; Threonine | 1976 |
Decomposition of phosphoserine and phosphothreonine during acid hydrolysis.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Hydrolysis; Organophosphorus Compounds; Phosphoproteins; Serine; Threonine | 1976 |
Turnover of transfer RNA species during development of the posterior silkgland of Bombyx mori L.
Topics: Alanine; Animals; Aspartic Acid; Bombyx; Glycine; Larva; Metamorphosis, Biological; RNA, Transfer; Sebaceous Glands; Serine; Threonine; Time Factors | 1976 |
Stereochemistry of the reaction of sheep liver threonine dehydratase. A nuclear magnetic resonance and optical rotatory dispersion study of its reaction pathway and products.
Topics: Alanine; Animals; Butyrates; Cysteine; Hydro-Lyases; Keto Acids; Liver; Magnetic Resonance Spectroscopy; Optical Rotatory Dispersion; Propionates; Serine; Sheep; Stereoisomerism; Threonine; Threonine Dehydratase | 1976 |
Metabolism of L-threonine and its relationship to sclerotium formation in Sclerotium rolfsii.
Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Carboxy-Lyases; Coenzyme A Ligases; Cycloheximide; Glucosyltransferases; Glycine; Glycine Hydroxymethyltransferase; Glyoxylates; Mitomycins; Mitosporic Fungi; Morphogenesis; Oxalates; Oxo-Acid-Lyases; p-Fluorophenylalanine; Serine; Stereoisomerism; Threonine | 1976 |
Phosphorylation of casein by mitochondrial protein kinase(s).
Topics: Animals; Caseins; Cytosol; Mitochondria, Liver; Phosphates; Protein Kinases; Rats; Serine; Threonine | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Free amino acids and amines in human dental plaque.
Topics: Alanine; Amines; Amino Acids; Aminobutyrates; Aspartic Acid; Cadaverine; Chemical Fractionation; Chromatography, Thin Layer; Dansyl Compounds; Dental Plaque; Fluorescence; Fluorometry; Glutamates; Glycine; Histamine; Humans; Ion Exchange; Lysine; Proline; Putrescine; Serine; Threonine; Valine | 1975 |
Carbohydrate moieties of procollagen: incorporation of isotopically labeled mannose and glucosamine into propeptides of procollagen secreted by matrix-free chick embryo tendon cells.
Topics: Animals; Chick Embryo; Chromatography, Gel; Collagen; Electrophoresis, Polyacrylamide Gel; Glucosamine; Hydrolysis; Mannose; Protein Precursors; Serine; Threonine | 1976 |
Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses.
Topics: Alanine; Amino Acids; Aminocaproates; Aminoisobutyric Acids; Animals; Asparagine; Bicuculline; Convulsants; Cystathionine; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Imidazoles; In Vitro Techniques; Isomerism; Leucine; Membrane Potentials; Nerve Endings; Neurons, Afferent; Picrotoxin; Rana pipiens; Serine; Spinal Cord; Strychnine; Taurine; Threonine; Valine | 1975 |
Effect of Acinetobacter glutaminase-asparaginase treatment on free amino acids in mouse tissues.
Topics: Acetyltransferases; Acinetobacter; Amino Acids; Ammonia; Animals; Asparaginase; Asparagine; Aspartic Acid; Body Weight; Brain; Escherichia coli; Female; Glutamates; Glutaminase; Glutamine; Kidney; Mice; Organ Size; Serine; Spleen; Threonine | 1975 |
Change of isoaccepting threonyl-tRNA and contitutively increased level of threonyl-tRNA-synthetase in E. coli.
Topics: Amino Acyl-tRNA Synthetases; Chromatography, DEAE-Cellulose; Escherichia coli; RNA, Bacterial; RNA, Transfer; Serine; Species Specificity; Threonine; Threonine-tRNA Ligase | 1975 |
Synthesis of the mannosyl-O-serine (threonine) linkage of glycoproteins from polyisoprenylphosphate mannose in yeast (Hansenula holstii).
Topics: Amino Acids; Ascomycota; Glycopeptides; Glycoproteins; Kinetics; Magnetic Resonance Spectroscopy; Mannose; Phospholipids; Polyethylene Glycols; Pronase; Saccharomycetales; Serine; Threonine | 1975 |
The removal of contaminating quadrol by boric acid extraction prior to mass spectralanalysis of amino acid thiazolinones.
Topics: Amino Acids; Aniline Compounds; Boric Acids; Ethylenediamines; Lysine; Mass Spectrometry; Methods; Phenylalanine; Serine; Thiazoles; Threonine | 1975 |
Ligand-exchange chromatography of amino acids on copper-, cobalt- and zinc-chelex 100.
Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Cobalt; Copper; Cysteine; Glutamates; Histidine; Ion Exchange Resins; Ligands; Lysine; Phenylalanine; Quaternary Ammonium Compounds; Serine; Threonine; Tyrosine; Zinc | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
Mechanistic, inhibitory and stereochemical studies on cytoplasmic and mitochondrial serine transhydorxymethylases.
Topics: Acetaldehyde; Aldehydes; Animals; Catalysis; Cytoplasm; Epoxy Compounds; Formaldehyde; Glycine; Glycine Hydroxymethyltransferase; Iodoacetamide; Isoenzymes; Mitochondria, Liver; Rabbits; Serine; Tetrahydrofolates; Threonine; Transferases | 1975 |
Methionine toxicity in the chick: nutritional and metabolic implications.
Topics: Adenine; Amino Acids; Animals; Arginine; Blood Glucose; Body Weight; Chickens; Glycine; Hypoglycemia; Isoleucine; Male; Methionine; Serine; Threonine | 1975 |
[Isolation and amino acid composition of two pathologically augmented proteins from psoriatic scales (author's transl)].
Topics: Alanine; Amino Acids; Electrophoresis, Disc; Galactosamine; Glycine; Humans; Leucine; Proteins; Psoriasis; Serine; Skin; Threonine | 1975 |
Developmental changes of free amino acids in bovine fetal fluids with gestational age and the interrelationships between the amino acid concentrations in the fluid compartments.
Topics: Alanine; Allantois; Amino Acids; Amniotic Fluid; Animals; Body Fluids; Cattle; Female; Fetal Blood; Fetus; Gastric Mucosa; Gestational Age; Methionine; Ornithine; Pregnancy; Serine; Stomach; Taurine; Threonine | 1975 |
[Some indices of nitrogen metabolism in patients with viral hepatitis].
Topics: Adolescent; Adult; Alanine; Ammonia; Asparagine; Chronic Disease; Cysteine; Cystinuria; Glutamates; Glycine; Hepatitis A; Humans; Isoleucine; Leucine; Methionine; Middle Aged; Nitrogen; Phenylalanine; Serine; Threonine; Urea; Valine | 1975 |
Characterization of neutral amino acid transport in a marine pseudomonad.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Glycine; Isoleucine; Kinetics; Leucine; Mutation; Pseudomonas; Seawater; Serine; Stereoisomerism; Threonine; Valine; Water Microbiology | 1975 |
Compartmentalization of amino acids in surfactant aggregates. Partitioning between water and aqueous micellar sodium deodecanoate and between hexane and dodecylammonium propionate trapped water in hexane.
Topics: Alanine; Alkanes; Amino Acids; Arginine; Aspartic Acid; Colloids; Glutamates; Glycine; Isoleucine; Laurates; Leucine; Lysine; Micelles; Phenylalanine; Proline; Serine; Solubility; Threonine; Valine | 1975 |
Transformation of some hydroxy amino acids to other amino acids.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Hot Temperature; Serine; Threonine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
[Studies on the modification of methionine imbalance in rats through the supplementation of threonine, serine, glycine or glutamic acid].
Topics: Animal Feed; Animals; Food Additives; Glutamates; Glycine; Methionine; Rats; Serine; Threonine | 1975 |
Phosphorylation of ribosome-associated proteins during the mammalian cell cycle. Unique phosphorylation of a specific protein during mitosis.
Topics: Cell Line; Mitosis; Phosphoproteins; Ribosomal Proteins; Ribosomes; Serine; Threonine | 1976 |
Studies on trypsin inhibitors. Part I. Synthesis of protected peptides related to sequence 1-10 of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Alanine; Animals; Arginine; Cysteine; Glutamine; Peptides; Proline; Serine; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Valine | 1976 |
Isolation, composition and reactivity of the neutral glycoproteins from human meconiums with specificities of the ABO and Lewis systems.
Topics: ABO Blood-Group System; Acetylgalactosamine; Acetylglucosamine; Amino Acids; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Fucose; Galactose; Glucosamine; Glycoproteins; Hemagglutination Inhibition Tests; Humans; Infant, Newborn; Lewis Blood Group Antigens; Meconium; Precipitins; Serine; Threonine | 1976 |
[The pattern of distribution of free amino acids in human amniotic fluid related to the duration of pregnancy. Part I: Changes in concentration in normal pregnancy (author's transl)].
Topics: Alanine; Amino Acids; Amniotic Fluid; Chromatography, Gas; Cysteine; Female; Gestational Age; Glycine; Humans; Hydroxyproline; Methionine; Ornithine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
Hydration of amino acid side chains: dependence on secondary structure.
Topics: Amino Acids; Computer Simulation; Hydrogen Bonding; Mathematical Computing; Models, Chemical; Models, Molecular; Protein Structure, Secondary; Serine; Software; Threonine; Tyrosine; Water | 1992 |
Probing the role of threonine and serine residues of E. coli asparaginase II by site-specific mutagenesis.
Topics: Amino Acid Sequence; Asparaginase; Base Sequence; Escherichia coli; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine | 1992 |
Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Rabbits; Rats; Serine; Signal Transduction; Threonine; Tyrosine | 1992 |
Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis; Cell Line; Cloning, Molecular; Humans; Membrane Proteins; Molecular Sequence Data; Open Reading Frames; Phosphorylation; Protein Kinases; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Sequence Alignment; Serine; Threonine | 1992 |
A purified S6 kinase kinase from Xenopus eggs activates S6 kinase II and autophosphorylates on serine, threonine, and tyrosine residues.
Topics: Animals; Caseins; Cell Line; Chromatography, Gel; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Histones; Isoenzymes; Phosphoric Monoester Hydrolases; Phosphorylation; Phosvitin; Protamines; Protein Kinase Inhibitors; Protein Kinases; Ribosomal Protein S6 Kinases; Serine; Substrate Specificity; Threonine; Tyrosine; Xenopus | 1992 |
The 93 kDa protein gephyrin and tubulin associated with the inhibitory glycine receptor are phosphorylated by an endogenous protein kinase.
Topics: Animals; Carrier Proteins; Glycine; Kinetics; Membrane Proteins; Phosphorylation; Protein Kinases; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Serine; Threonine; Tubulin | 1992 |
Functional domains of membrane-bound human thrombomodulin. EGF-like domains four to six and the serine/threonine-rich domain are required for cofactor activity.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Chromosome Deletion; Epidermal Growth Factor; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Conformation; Receptors, Cell Surface; Receptors, Thrombin; Restriction Mapping; Serine; Threonine; Thrombin; Transfection | 1992 |
Serine residues responsible for tetracycline transport are on a vertical stripe including Asp-84 on one side of transmembrane helix 3 in transposon Tn10-encoded tetracycline/H+ antiporter of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Base Sequence; Biological Transport; Carrier Proteins; Cell Membrane; Cysteine; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Immunoblotting; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Repressor Proteins; Serine; Tetracycline; Threonine | 1992 |
Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity.
Topics: Cell Line; Chromatography, Affinity; Glutathione Transferase; Humans; Kinetics; Leukemia; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Protein Phosphatase 2; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine | 1992 |
Involvement of MAP kinase activators in angiotensin II-induced activation of MAP kinases in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinases; Rats; Serine; Threonine; Tyrosine | 1992 |
Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing.
Topics: Blotting, Northern; Cell Extracts; Cell Nucleus; Chromatography, Affinity; HeLa Cells; Humans; Phosphoprotein Phosphatases; Phosphorylation; RNA Precursors; RNA Splicing; Serine; Threonine | 1992 |
Adsorption from salivary fractions at solid/liquid and air/liquid interfaces.
Topics: Adsorption; Chromatography; Histidine; Humans; Proline; Saliva; Salivary Proteins and Peptides; Serine; Silicon Dioxide; Surface Properties; Surface Tension; Threonine; Water | 1992 |
Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cell Line; Chromatography, Affinity; Colforsin; Cyclic AMP; Epidermal Growth Factor; Immunoblotting; Kinetics; Molecular Sequence Data; Oncogene Proteins; Organ Specificity; PC12 Cells; Phosphorylation; Precipitin Tests; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Serine; Tetradecanoylphorbol Acetate; Threonine; Type C Phospholipases | 1992 |
TGF beta signals through a heteromeric protein kinase receptor complex.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cell Line; Mink; Models, Biological; Molecular Sequence Data; Multienzyme Complexes; Protein Kinases; Receptors, Cell Surface; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta | 1992 |
Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Dynorphins; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Kinetics; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Inbred Strains; Serine; Stereotaxic Techniques; Taurine; Threonine | 1992 |
Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Blotting, Northern; Cell Line; Cloning, Molecular; DNA; Glutamates; Glutamic Acid; Hematopoietic Stem Cells; Histocompatibility Antigens; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Leukocyte Common Antigens; Male; Mice; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Organ Specificity; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; RNA; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; Substrate Specificity; Threonine | 1992 |
A serine, threonine and proline-rich region near the carboxyl-terminus of a rat intestinal mucin peptide.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; DNA; Intestinal Mucosa; Molecular Sequence Data; Mucins; Proline; Rats; Repetitive Sequences, Nucleic Acid; Restriction Mapping; RNA; RNA, Messenger; Sequence Homology, Nucleic Acid; Serine; Threonine | 1992 |
The roles of serine and threonine sidechains in ion channels: a modelling study.
Topics: Amino Acid Sequence; Animals; Calorimetry; Hydrogen Bonding; Ion Channels; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Receptors, Serotonin; Sequence Homology, Amino Acid; Serine; Threonine; Torpedo | 1992 |
Synthesis and conformational and NMR studies of alpha-D-mannopyranosyl and alpha-D-mannopyranosyl-(1----2)-alpha-D-mannopyranosyl linked to L-serine and L-threonine.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Computer Simulation; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mannose; Mannosides; Models, Molecular; Molecular Sequence Data; Molecular Structure; Serine; Threonine | 1992 |
Isolation and partial characterization of serine- and threonine-rich porcine gastric mucus glycopeptides.
Topics: Alcian Blue; Amino Acids; Animals; Carbohydrates; Centrifugation, Density Gradient; Chromatography, Liquid; Electrophoresis, Cellulose Acetate; Gastric Mucosa; Glycopeptides; Mucus; Oligosaccharides; Pepsin A; Serine; Swine; Threonine | 1992 |
Protein kinase C phosphorylates both serine and threonine residues of the mRNA cap binding protein eIF-4E.
Topics: Amino Acid Sequence; Amino Acids; Catalysis; Eukaryotic Initiation Factor-4E; Humans; Molecular Sequence Data; Peptide Initiation Factors; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Binding; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Serine; Threonine | 1992 |
Novel isoforms of CaBP 33/37 (annexin V) from mammalian brain: structural and phosphorylation differences that suggest distinct biological roles.
Topics: Amino Acid Sequence; Animals; Annexin A5; Brain Chemistry; Cattle; Glutamine; Lysine; Membrane Proteins; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Rats; Sequence Alignment; Serine; Threonine | 1992 |
Phosphorylation of p90 and p52 in response to phorbol-esters in Swiss/3T3 cells overexpressing protein kinase C-alpha.
Topics: 3T3 Cells; Animals; Enzyme Activation; Fibroblast Growth Factors; Intracellular Signaling Peptides and Proteins; Isoenzymes; Membrane Proteins; Mice; Mitosis; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol Esters; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Proteins; Serine; Signal Transduction; Threonine | 1992 |
[The intravascular transfer of glycine during percutaneous kidney surgery].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Glycine; Hemodilution; Humans; Male; Middle Aged; Nephrostomy, Percutaneous; Prospective Studies; Serine; Sodium; Syndrome; Therapeutic Irrigation; Threonine | 1992 |
Casein kinase II-catalysed phosphorylation of calmodulin is altered by amino acid deletions in the central helix of calmodulin.
Topics: Amino Acid Sequence; Binding Sites; Calcium; Calmodulin; Casein Kinase II; Escherichia coli; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Secondary; Sequence Deletion; Serine; Substrate Specificity; Threonine | 1992 |
Design and inhibitory properties of synthetic Bowman-Birk loops.
Topics: Amino Acid Sequence; Binding, Competitive; Kinetics; Models, Molecular; Models, Structural; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Protein Conformation; Serine; Structure-Activity Relationship; Threonine; Trypsin Inhibitor, Bowman-Birk Soybean | 1992 |
Novel protein kinase of Arabidopsis thaliana (APK1) that phosphorylates tyrosine, serine and threonine.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Base Sequence; Blotting, Southern; Cloning, Molecular; DNA; Escherichia coli; Humans; Immunoblotting; Molecular Sequence Data; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Serine; Threonine; Tyrosine | 1992 |
Biosynthesis and glycosylation of serine/threonine-rich secreted proteins from Toxocara canis larvae.
Topics: Animals; Antigens, Helminth; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Glycosylation; Helminth Proteins; Polysaccharides; Precipitin Tests; Serine; Threonine; Toxocara canis | 1992 |
Autophosphorylation of the catalytic subunit of cAMP-dependent protein kinase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Histones; Kinetics; Macromolecular Substances; Molecular Sequence Data; Myocardium; Oligopeptides; Peptide Fragments; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Serine; Swine; Threonine; Trypsin | 1992 |
Insulin-stimulated phosphorylation of calmodulin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Calmodulin; Casein Kinases; Cells, Cultured; Chromatography, High Pressure Liquid; Insulin; Liver; Molecular Sequence Data; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Kinases; Rats; Serine; Substrate Specificity; Threonine | 1992 |
Phosphorylation of Escherichia coli translation initiation factors by the bacteriophage T7 protein kinase.
Topics: Electrophoresis, Polyacrylamide Gel; Escherichia coli; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinases; Protein Serine-Threonine Kinases; Serine; T-Phages; Threonine | 1992 |
The comparative efficiencies of the Ser(P)-, Thr(P)- and Tyr(P)-residues as specificity determinants for casein kinase-1.
Topics: Amino Acid Sequence; Casein Kinases; Indicators and Reagents; Kinetics; Molecular Sequence Data; Oligopeptides; Protein Kinases; Serine; Substrate Specificity; Threonine; Tyrosine | 1992 |
Serine-376 contributes to the binding of substrate by ribulose-bisphosphate carboxylase/oxygenase from Anacystis nidulans.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cyanobacteria; Cysteine; Enzyme Activation; Kinetics; Mutagenesis, Site-Directed; Protein Binding; Ribulose-Bisphosphate Carboxylase; Serine; Substrate Specificity; Threonine | 1992 |
Threonine 183 and adjacent flexible loop residues in the tryptophan synthase alpha subunit have critical roles in modulating the enzymatic activities of the beta subunit in the alpha 2 beta 2 complex.
Topics: Amino Acid Sequence; Catalysis; Electrophoresis, Polyacrylamide Gel; Fluorescence; Glycerophosphates; Hydrolysis; Indoles; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Salmonella typhimurium; Serine; Threonine; Tryptophan Synthase | 1992 |
The vaccinia virus B1R gene product is a serine/threonine protein kinase.
Topics: Adenosine Triphosphate; Base Sequence; Binding Sites; Caseins; Cloning, Molecular; Escherichia coli; Glutathione Synthase; Histones; Molecular Sequence Data; Phosphorylation; Protein Kinases; Serine; Substrate Specificity; T-Phages; Threonine; Vaccinia virus; Viral Proteins; Virion | 1992 |
Characterization of the molecular mechanism involved in the activation of hyaluronan synthetase by platelet-derived growth factor in human mesothelial cells.
Topics: Cell Membrane; Cells, Cultured; Cycloheximide; Enzyme Activation; Epithelial Cells; Epithelium; Glucuronosyltransferase; Glycosyltransferases; Humans; Hyaluronan Synthases; Kinetics; Membrane Proteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Biosynthesis; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Threonine; Transferases; Transforming Growth Factor beta; Tyrosine; Vanadates; Xenopus Proteins | 1992 |
Introduction of hydroxyl-bearing amino acids causes bathochromic spectral shifts in rhodopsin. Amino acid substitutions responsible for red-green color pigment spectral tuning.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Line; Humans; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Restriction Mapping; Rhodopsin; Serine; Spectrophotometry; Threonine; Transfection; Tyrosine | 1992 |
A putative serine/threonine protein kinase gene on chromosome III of Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Base Sequence; Chromosomes, Fungal; Cloning, Molecular; Genes, Fungal; Molecular Sequence Data; Mutagenesis; Nucleic Acid Hybridization; Protein Kinases; Restriction Mapping; Saccharomyces cerevisiae; Sequence Homology, Nucleic Acid; Serine; Threonine | 1992 |
A structural polypeptide of the baculovirus Autographa californica nuclear polyhedrosis virus contains O-linked N-acetylglucosamine.
Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; Baculoviridae; Cells, Cultured; Glycoproteins; Lectins; Serine; Threonine; Viral Envelope Proteins; Viral Structural Proteins | 1992 |
[Mechanism of the effect of serine and threonine on ammoniagenesis and biosynthesis of orotate in the mouse].
Topics: Adenine; Ammonia; Animals; Aspartic Acid; Cycloheximide; Male; Mice; Mice, Inbred ICR; Orotic Acid; Phosphonoacetic Acid; Serine; Threonine | 1992 |
Vaccinia virus B1 kinase: phenotypic analysis of temperature-sensitive mutants and enzymatic characterization of recombinant proteins.
Topics: Alleles; Animals; Base Sequence; Cell Line; DNA Replication; DNA, Viral; Escherichia coli; L Cells; Mice; Molecular Sequence Data; Mutation; Phenotype; Recombinant Proteins; Serine; Substrate Specificity; Temperature; Threonine; Vaccinia virus; Viral Proteins | 1992 |
Serine and threonine catabolism in Saccharomyces cerevisiae: the CHA1 polypeptide is homologous with other serine and threonine dehydratases.
Topics: Amino Acid Sequence; Base Sequence; Codon; DNA, Fungal; Genes, Fungal; L-Serine Dehydratase; Molecular Sequence Data; Plasmids; Restriction Mapping; Saccharomyces cerevisiae; Sequence Homology, Nucleic Acid; Serine; Threonine; Threonine Dehydratase | 1992 |
DIDS-effect on Ser/Thr- and Tyr-phosphorylation of membrane proteins in human erythrocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anion Exchange Protein 1, Erythrocyte; Binding Sites; Erythrocyte Membrane; Humans; In Vitro Techniques; Membrane Proteins; Phosphorylation; Serine; Spectrin; Threonine; Tyrosine | 1992 |
The hamster transferrin receptor contains Ser/Thr-linked oligosaccharides: use of a lectin-resistant CHO cell line to identify glycoproteins containing these linkages.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Chemical Precipitation; CHO Cells; Chromatography, Affinity; Cricetinae; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Lectins; Molecular Sequence Data; Oligosaccharides; Receptors, Transferrin; Serine; Threonine | 1992 |
The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs.
Topics: Alzheimer Disease; Amino Acid Sequence; Brain; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Humans; Microtubules; Molecular Sequence Data; Mutation; Phosphorylation; Proline; Protein Binding; Protein Kinases; Serine; tau Proteins; Threonine | 1992 |
pp54 microtubule-associated protein-2 kinase requires both tyrosine and serine/threonine phosphorylation for activity.
Topics: Animals; Blotting, Western; Brain; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Phosphoprotein Phosphatases; Phosphorylation; Precipitin Tests; Protein Kinase Inhibitors; Protein Kinases; Protein Phosphatase 1; Rabbits; Rats; Serine; Threonine; Tyrosine | 1991 |
L-alanine binding sites and Na+, K(+)-ATPase in cilia and other membrane fractions from olfactory rosettes of Atlantic salmon.
Topics: Alanine; Animals; Binding Sites; Cell Membrane; Cilia; Hydrogen-Ion Concentration; Mercuric Chloride; Olfactory Mucosa; Salmon; Serine; Sodium-Potassium-Exchanging ATPase; Threonine | 1991 |
Thrombin-induced effects are selectively inhibited following treatment of intact human platelets with okadaic acid.
Topics: Blood Platelets; Carrier Proteins; Endoribonucleases; Ethers, Cyclic; Humans; Intracellular Signaling Peptides and Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Platelet Activation; Proteins; RNA-Binding Proteins; Serine; Serotonin; Threonine; Thrombin | 1991 |
Multisite serine phosphorylation of the insulin and IGF-I receptors in transfected cells.
Topics: Animals; Cell Line; Fibroblasts; Insulin; Insulin-Like Growth Factor I; Peptide Mapping; Phosphorylation; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Serine; Tetradecanoylphorbol Acetate; Threonine; Transfection | 1991 |
Effects of 17-hydroxywortmannin on serine/threonine-protein kinases in human blood platelets.
Topics: Androstadienes; Blood Platelets; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Humans; Kinetics; Platelet Activation; Protein Denaturation; Protein Kinases; Serine; Threonine | 1991 |
A serine/threonine proline kinase activity is included in the tau protein kinase fraction forming a paired helical filament epitope.
Topics: Amino Acid Sequence; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Molecular Sequence Data; Phosphorylation; Protein Kinases; Serine; tau Proteins; Threonine | 1991 |
Inhibition of steroidogenesis in rat adrenal cortex cells by a threonine analogue.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Corticosterone; Female; Phosphorylation; Rats; Rats, Inbred Strains; Serine; Steroids; Threonine | 1991 |
Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein.
Topics: Avian Sarcoma Viruses; Base Sequence; DNA Nucleotidyltransferases; DNA, Viral; Glycerol; HIV-1; HIV-2; Humans; Hydrolysis; Integrases; Molecular Sequence Data; Nucleotides; Propylene Glycol; Propylene Glycols; Sensitivity and Specificity; Serine; Threonine; Viral Proteins | 1991 |
Synthesis, stereochemistry, and biological properties of the depigmenting agents, melanostatin, feldamycin and analogs.
Topics: Animals; Anti-Bacterial Agents; Histidine; Melanins; Melanoma, Experimental; Molecular Conformation; MSH Release-Inhibiting Hormone; Serine; Streptomyces; Threonine; Tumor Cells, Cultured | 1991 |
Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody.
Topics: Antibodies, Monoclonal; Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Half-Life; Methylamines; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1990 |
Determination of dityrosine, phosphotyrosine, phosphothreonine, and phosphoserine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Microchemistry; p-Dimethylaminoazobenzene; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Serine; Threonine; Tyrosine | 1990 |
[Phosphoamino acid analysis by 2-dimensional electrophoresis].
Topics: Electrophoresis, Gel, Two-Dimensional; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1990 |
The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110.
Topics: Animals; Antibodies, Monoclonal; Chick Embryo; Mutagenesis; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Sequence Homology, Nucleic Acid; Serine; Structure-Activity Relationship; Subcellular Fractions; Threonine; Tyrosine | 1991 |
Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Cell Line; Cloning, Molecular; Complement System Proteins; DNA, Neoplasm; Exons; Genomic Library; HeLa Cells; Humans; Membrane Cofactor Protein; Membrane Glycoproteins; Molecular Sequence Data; Oligonucleotide Probes; Phenotype; Poly A; Polymerase Chain Reaction; Proline; RNA; RNA Splicing; RNA, Messenger; Serine; Threonine; Transfection | 1991 |
Control of ligand specificity in cyclic nucleotide-gated channels from rod photoreceptors and olfactory epithelium.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cattle; Cyclic AMP; Cyclic GMP; DNA Mutational Analysis; Electric Conductivity; Ion Channel Gating; Ion Channels; Ligands; Molecular Sequence Data; Photoreceptor Cells; Protein Kinases; Sequence Alignment; Serine; Smell; Threonine; Xenopus laevis | 1991 |
A novel polymorphism of apolipoprotein A-IV is the result of an asparagine to serine substitution at residue 127.
Topics: Alleles; Amino Acid Sequence; Apolipoproteins A; Asparagine; Base Sequence; Cholesterol; Codon; Genotype; Humans; Hyperlipidemias; Lipoproteins; Male; Molecular Sequence Data; Myocardial Infarction; Polymorphism, Genetic; Serine; Threonine; Triglycerides | 1992 |
Signal transduction in human B cells during aging: alterations in stimulus-induced phosphorylations of tyrosine and serine/threonine substrates and in cytosolic calcium responsiveness.
Topics: Aging; Amino Acids; B-Lymphocytes; Calcium; Cell Division; Cells, Cultured; Cytosol; Humans; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Ribonucleases; Serine; Signal Transduction; Threonine; Tyrosine | 1991 |
Partial purification of a mannosyltransferase involved in the O-mannosylation of glycoproteins from Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Dolichol Monophosphate Mannose; Kinetics; Magnesium; Mannosyltransferases; Molecular Sequence Data; Oligopeptides; Phosphatidylcholines; Phospholipids; Saccharomyces cerevisiae; Serine; Substrate Specificity; Threonine | 1991 |
High-sensitivity FAB-MS strategies for O-GlcNAc characterization.
Topics: Acetylgalactosamine; Amino Acid Sequence; Binding Sites; Carbohydrate Sequence; Glycopeptides; Glycophorins; Indicators and Reagents; Molecular Sequence Data; Neuraminidase; Oligopeptides; Serine; Spectrometry, Mass, Fast Atom Bombardment; Threonine | 1991 |
Maturation of the yeast plasma membrane [H+]ATPase involves phosphorylation during intracellular transport.
Topics: Biological Transport; Blotting, Western; Endoplasmic Reticulum; Enzyme Activation; Fungal Proteins; Glucose; Kinetics; Membrane Proteins; Mutation; Phosphoproteins; Phosphorylation; Proton-Translocating ATPases; Saccharomyces cerevisiae; Serine; Temperature; Threonine | 1991 |
Changes in insulin-receptor tyrosine, serine and threonine phosphorylation as a result of substitution of tyrosine-1162 with phenylalanine.
Topics: Amino Acid Sequence; Animals; Cell Line; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Threonine; Transfection; Trypsin; Tyrosine | 1991 |
Identification, purification, and characterization of a novel serine/threonine protein phosphatase from bovine brain.
Topics: Amino Acid Sequence; Animals; Brain; Catalysis; Cattle; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Heparin; Molecular Sequence Data; Phosphoprotein Phosphatases; Phosphorylation; Protamines; Serine; Threonine | 1991 |
Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation.
Topics: Amino Acid Sequence; Bacteriorhodopsins; Darkness; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Light; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protons; Restriction Mapping; Serine; Spectrophotometry; Threonine | 1991 |
Insulin-EGF receptor chimerae mediate tyrosine transphosphorylation and serine/threonine phosphorylation of kinase-deficient EGF receptors.
Topics: ErbB Receptors; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Recombinant Proteins; Serine; Threonine; Tyrosine | 1991 |
The dysfunctional LDL receptor in a monensin-resistant mutant of Chinese hamster ovary cells lacks selected O-linked oligosaccharides.
Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Asparagine; Carbohydrate Conformation; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Female; Glycopeptides; Glycosylation; Humans; Monensin; Mutation; Oligosaccharides; Receptors, LDL; Serine; Threonine | 1991 |
Spk1, a new kinase from Saccharomyces cerevisiae, phosphorylates proteins on serine, threonine, and tyrosine.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Cycle Proteins; Checkpoint Kinase 2; Cloning, Molecular; Escherichia coli; Fungal Proteins; Gene Library; Genes, Fungal; Immunoblotting; Molecular Sequence Data; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Nucleic Acid; Serine; Substrate Specificity; Threonine; Tyrosine | 1991 |
Phosphorylation of basic fibroblast growth factor by purified protein kinase C and the identification of a cryptic site of phosphorylation.
Topics: Animals; Brain; Cattle; Fibroblast Growth Factor 2; Humans; Peptide Fragments; Peptide Mapping; Phosphorylation; Protein Kinase C; Recombinant Proteins; Serine; Threonine; Trypsin | 1991 |
Insulin and platelet-derived growth factor stimulate phosphorylation of the c-raf product at serine and threonine residues in intact cells.
Topics: Base Sequence; Cell Line; Electrophoresis, Polyacrylamide Gel; Insulin; Molecular Sequence Data; Oncogene Proteins v-raf; Peptide Mapping; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein-Tyrosine Kinases; Retroviridae Proteins, Oncogenic; Serine; Threonine | 1991 |
Aminoaciduria as a marker of acute renal transplant rejection--a patient study.
Topics: Adolescent; Alanine; Amino Acids; Child; Child, Preschool; Creatinine; Female; Glycine; Graft Rejection; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Serine; Threonine | 1991 |
Antithrombin Cambridge II, 384 Ala to Ser. Further evidence of the role of the reactive centre loop in the inhibitory function of the serpins.
Topics: Aged; Alanine; Antithrombin III; Base Sequence; Binding Sites; Exons; Heparin; Humans; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proline; Protein Conformation; Serine; Serpins; Threonine; Thrombophlebitis; United Kingdom | 1991 |
Inhibition of homoserine dehydrogenase I by L-serine in Escherichia coli.
Topics: Cations, Monovalent; Cysteine; Escherichia coli; Homoserine Dehydrogenase; Hydrogen-Ion Concentration; Kinetics; Potassium; Serine; Threonine | 1991 |
Glycosylation sites identified by detection of glycosylated amino acids released from Edman degradation: the identification of Xaa-Pro-Xaa-Xaa as a motif for Thr-O-glycosylation.
Topics: Amino Acid Sequence; Animals; Cell Line; Glycopeptides; Glycosylation; Humans; Molecular Sequence Data; Peptide Fragments; Proline; Proteins; Rats; Serine; Threonine; Transfection | 1991 |
Conformational mobility of His-64 in the Thr-200----Ser mutant of human carbonic anhydrase II.
Topics: Carbonic Anhydrases; Computer Graphics; DNA Mutational Analysis; Esterases; Fourier Analysis; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Ligands; Motion; Protein Conformation; Serine; Structure-Activity Relationship; Threonine; Zinc | 1991 |
Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Asparagine; Binding Sites; Calcium; Calmodulin; Drosophila melanogaster; Glutamine; Glycine; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Molecular Structure; Proline; Recombinant Proteins; Serine; Solutions; Threonine | 1991 |
Identification and characterization of a novel cytoskeleton-associated pp60src substrate.
Topics: Amino Acid Sequence; Animals; Avian Proteins; Base Sequence; Blotting, Northern; Blotting, Western; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cloning, Molecular; Cytoskeletal Proteins; Cytoskeleton; Microscopy, Fluorescence; Molecular Sequence Data; Oncogene Protein pp60(v-src); Phosphorylation; Protein Conformation; Repetitive Sequences, Nucleic Acid; Serine; Threonine; Tyrosine | 1991 |
Insulin-stimulated serine and threonine phosphorylation of the human insulin receptor. An assessment of the role of serines 1305/1306 and threonine 1348 by their replacement with neutral or negatively charged amino acids.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Humans; Insulin; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptides; Phosphopeptides; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Substrate Specificity; Threonine; Transfection | 1991 |
Pest sequences present in the subunits of phosphorylase kinase.
Topics: Amino Acid Sequence; Animals; Glutamates; Glutamic Acid; Humans; Molecular Sequence Data; Muscles; Phosphorylase Kinase; Proline; Rabbits; Serine; Threonine | 1990 |
Recovery of tryptophan in peptides and proteins by high-temperature and short-term acid hydrolysis in the presence of phenol.
Topics: Chromatography, High Pressure Liquid; Cnidarian Venoms; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Lectins; Membranes, Artificial; p-Dimethylaminoazobenzene; Peptides; Phenol; Phenols; Polyvinyls; Proteins; Rosaniline Dyes; Serine; Sodium Dodecyl Sulfate; Threonine; Time Factors; Tryptophan | 1990 |
Role of threonine residue 154 in ligand recognition of the tar chemoreceptor in Escherichia coli.
Topics: Aspartic Acid; Bacterial Proteins; Chemoreceptor Cells; Chemotaxis; Escherichia coli; Escherichia coli Proteins; Hot Temperature; Maltose; Membrane Proteins; Methylation; Mutation; Phenols; Receptors, Cell Surface; Serine; Structure-Activity Relationship; Threonine | 1990 |
Isolation and characterization of major urinary amino acid O-glycosides and a dipeptide O-glycoside from a new lysosomal storage disorder (Kanzaki disease). Excessive excretion of serine- and threonine-linked glycan in the patient urine.
Topics: Carbohydrate Metabolism, Inborn Errors; Carbohydrate Sequence; Chromatography, Thin Layer; Glycopeptides; Glycosides; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Serine; Threonine | 1990 |
Multisite phosphorylation of the epidermal growth factor receptor. Use of site-directed mutagenesis to examine the role of serine/threonine phosphorylation.
Topics: Amino Acid Sequence; Amino Acids; Animals; Cell Line; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Humans; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Peptide Fragments; Phosphopeptides; Phosphorylation; Plasmids; Platelet-Derived Growth Factor; Serine; Threonine; Thymidine | 1990 |
Association of catalytic and regulatory subunits of cyclic AMP-dependent protein kinase requires a negatively charged side group at a conserved threonine.
Topics: Amino Acid Sequence; DNA Mutational Analysis; Kinetics; Macromolecular Substances; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Protein Binding; Protein Kinases; Saccharomyces cerevisiae; Serine; Structure-Activity Relationship; Threonine | 1990 |
Sequencing of peptides and proteins with blocked N-terminal amino acids: N-acetylserine or N-acetylthreonine.
Topics: Amino Acid Sequence; Animals; Cattle; Humans; Indicators and Reagents; Methods; Molecular Sequence Data; Peptides; Phenylthiohydantoin; Proteins; Rats; Serine; Threonine; Thymosin | 1990 |
Labeling of human clots in vitro with an active-site mutant of t-PA.
Topics: Humans; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Mutation; Radionuclide Imaging; Serine; Threonine; Thrombosis; Tissue Plasminogen Activator | 1990 |
Effects of feeding rats low protein diets containing casein or soy protein isolate supplemented with methionine or oligo-L-methionine.
Topics: Amino Acids; Animals; Caseins; Dietary Proteins; Digestion; Food, Fortified; Glycine max; Lipid Metabolism; Liver; Male; Methionine; Plant Proteins, Dietary; Rats; Rats, Inbred Strains; Serine; Soybean Proteins; Threonine | 1990 |
The ring-infected erythrocyte surface antigen protein of Plasmodium falciparum is phosphorylated upon association with the host cell membrane.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Antigens, Protozoan; Antigens, Surface; Erythrocyte Membrane; Immunoblotting; Phosphorus Radioisotopes; Phosphorylation; Plasmodium falciparum; Precipitin Tests; Protozoan Proteins; Serine; Threonine | 1990 |
Nuclear pp64 is phosphorylated in both serine/threonine and tyrosine through complex pathways regulated by 12-O-tetradecanoylphorbol-13-acetate and platelet-derived growth factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Dimethyl Sulfoxide; Epidermal Growth Factor; Isoquinolines; Kinetics; Nuclear Proteins; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1990 |
Two-dimensional NMR studies of staphylococcal nuclease. 1. Sequence-specific assignments of hydrogen-1 signals and solution structure of the nuclease H124L-thymidine 3',5'-bisphosphate-Ca2+ ternary complex.
Topics: Alanine; Amino Acid Sequence; Calcium; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Molecular Sequence Data; Molecular Structure; Protein Conformation; Serine; Solutions; Threonine; Thymine Nucleotides; Valine | 1990 |
Range of the influence of the carbohydrate moiety on the conformation of the poly(amino acid) backbone in glycosylated mucins.
Topics: Amino Acid Sequence; Animals; Carbohydrate Metabolism; Chemical Phenomena; Chemistry, Physical; Glycosylation; Mathematical Computing; Molecular Weight; Mucins; Peptide Fragments; Peptides; Protein Conformation; Serine; Submandibular Gland; Swine; Threonine | 1990 |
Modifications of substituted seryl and threonyl residues in phosphopeptides and a polysialoglycoprotein by beta-elimination and nucleophile additions.
Topics: Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Kinetics; Molecular Sequence Data; Phosphopeptides; Salmon; Serine; Sialoglycoproteins; Threonine | 1990 |
Metabolic depletion effect on serine/threonine- and tyrosine-phosphorylations of membrane proteins in human erythrocytes.
Topics: Autoradiography; Biological Transport; Casein Kinases; Cell Membrane Permeability; Cytosol; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Proteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1990 |
[Conformation analysis of the N-glycosylation site Asn-X-Thr/Ser in glycoproteins].
Topics: Amino Acid Sequence; Asparagine; Glycolipids; Glycoproteins; Glycosylation; Models, Molecular; Molecular Sequence Data; Protein Conformation; Serine; Threonine | 1990 |
Influence of secondary structure on the hydration of serine, threonine and tyrosine residues in proteins.
Topics: Amino Acids; Protein Conformation; Proteins; Serine; Stereoisomerism; Threonine; Tyrosine; Water; X-Ray Diffraction | 1990 |
Mutational removal of the Thr669 and Ser671 phosphorylation sites alters substrate specificity and ligand-induced internalization of the epidermal growth factor receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Casein Kinases; Cell Line; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Kinetics; Ligands; Mice; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Oligopeptides; Phosphorylation; Protein Kinases; Restriction Mapping; Serine; Substrate Specificity; Threonine; Transcription, Genetic; Transfection | 1990 |
cdc2/pp56-62 are in vitro substrates for the tyrosine kinase encoded by the v-fms oncogene.
Topics: CDC2 Protein Kinase; Oncogene Protein gp140(v-fms); Phosphoproteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Retroviridae Proteins, Oncogenic; Serine; Threonine | 1990 |
Resonance Raman study on mutant cytochrome P-450 obtained by site-directed mutagenesis.
Topics: Animals; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Microsomes, Liver; Mixed Function Oxygenases; Mutation; Oxidation-Reduction; Protein Conformation; Rabbits; Saccharomyces cerevisiae; Serine; Spectrum Analysis, Raman; Threonine; Valine | 1990 |
Compound heterozygote for lipoprotein lipase deficiency: Ser----Thr244 and transition in 3' splice site of intron 2 (AG----AA) in the lipoprotein lipase gene.
Topics: Amino Acid Sequence; Apolipoproteins; Base Sequence; Child; Cloning, Molecular; DNA; DNA Mutational Analysis; Female; Heterozygote; Humans; Hyperlipoproteinemia Type I; Introns; Lipids; Lipoprotein Lipase; Male; Molecular Sequence Data; Mutation; Pedigree; Plasmids; Serine; Threonine | 1990 |
Linear dichroism studies of tryptophanase and its quasisubstrate complexes oriented in polyacrylamide gel.
Topics: Alanine; Binding Sites; Escherichia coli; Ligands; Oxindoles; Protein Binding; Protein Conformation; Serine; Spectrum Analysis; Threonine; Tryptophanase | 1990 |
Insulin activates a 70-kDa S6 kinase through serine/threonine-specific phosphorylation of the enzyme polypeptide.
Topics: Animals; Cell Line; Cycloheximide; Enzyme Activation; Insulin; Kinetics; Liver; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Kinases; Rats; Ribosomal Protein S6 Kinases; Serine; Threonine; Trypsin | 1990 |
[The c-raf oncogene].
Topics: Amino Acid Sequence; Animals; DNA, Neoplasm; Humans; Molecular Sequence Data; Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogenes; Serine; Signal Transduction; Threonine; Transfection | 1990 |
Effects of protein phosphorylation with p43v-abl and protein kinase A catalytic subunit on fluorescence intensity.
Topics: Histones; Phosphopyruvate Hydratase; Phosphorylation; Protein Conformation; Protein Kinases; Serine; Spectrometry, Fluorescence; Threonine; Tyrosine | 1990 |
Okadaic acid stimulates the activity of microtubule associated protein kinase in PC-12 pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Epidermal Growth Factor; Ethers, Cyclic; Nerve Growth Factors; Okadaic Acid; Pheochromocytoma; Phosphorylation; Protein Kinases; Serine; Swine; Threonine; Tumor Cells, Cultured | 1990 |
Calcium/calmodulin-independent autophosphorylation sites of calcium/calmodulin-dependent protein kinase II. Studies on the effect of phosphorylation of threonine 305/306 and serine 314 on calmodulin binding using synthetic peptides.
Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cattle; Chromatography, High Pressure Liquid; Egtazic Acid; Enzyme Activation; Kinetics; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinases; Rats; Serine; Threonine | 1990 |
pp54 microtubule-associated protein 2 kinase. A novel serine/threonine protein kinase regulated by phosphorylation and stimulated by poly-L-lysine.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Cycloheximide; Cytosol; Homeostasis; Insulin; Kinetics; Liver; Male; Molecular Weight; Phosphorylation; Polylysine; Protein Kinases; Rats; Serine; Threonine | 1990 |
A simple and rapid method of quantitative analysis of phosphoamino acids by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1985 |
Resolution and identification of O-phosphoserine, O-phosphothreonine, O-phosphotyrosine, and gamma-carboxyglutamic acid as their fluorescent o-phthalaldehyde derivatives by high performance liquid chromatography.
Topics: 1-Carboxyglutamic Acid; Animals; Chromatography, High Pressure Liquid; Fluorescent Dyes; o-Phthalaldehyde; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1986 |
Determination of [32P]phosphoamino acids in protein hydrolysates by isocratic anion-exchange high-performance liquid chromatography.
Topics: Buffers; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Serine; Spectrophotometry, Ultraviolet; Threonine; Tyrosine | 1988 |
Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; Chickens; Fibroblasts; Growth Substances; Maturation-Promoting Factor; Mesothelin; Mice; Mice, Inbred Strains; Mitosis; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Serine; Threonine; Trypsin | 1989 |
Thin-layer chromatography can resolve phosphotyrosine, phosphoserine, and phosphothreonine in a protein hydrolyzate.
Topics: Animals; Autoradiography; Chromatography, Thin Layer; Humans; Hydrolysis; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1989 |
Antibodies and radioimmunoassays for phosphoserine, phosphothreonine and phosphotyrosine. Serologic specificities and levels of the phosphoamino acids in cytoplasmic fractions of rat tissues.
Topics: Animals; Antibodies; Antibody Specificity; Chromatography, Ion Exchange; Cytoplasm; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred F344; Serine; Serum Albumin, Bovine; Threonine; Tyrosine | 1989 |
Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase).
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Asparagine; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Decanoic Acids; DNA; Isoleucine; Lauric Acids; Microsomes, Liver; Mixed Function Oxygenases; Mutation; Progesterone; Rabbits; Saccharomyces cerevisiae; Serine; Spectrophotometry; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Testosterone; Threonine; Transformation, Genetic; Valine | 1989 |
Effects of exogenous amino acids on the multiplication of porcine Escherichia coli.
Topics: Amino Acids; Animals; Aspartic Acid; Colony Count, Microbial; Culture Media; Escherichia coli; Lysine; Norleucine; Serine; Swine; Threonine; Valine | 1989 |
A new antitumor antibiotic, FR900840. II. Structural elucidation of FR900840.
Topics: Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hydrogenation; Hydrolysis; Hydroxybutyrates; Magnetic Resonance Spectroscopy; Mass Spectrometry; Serine; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Streptomyces; Threonine | 1989 |
Characterization of interaction of active-site serine mutants of tissue-type plasminogen activator with plasminogen activator inhibitor-1.
Topics: Base Sequence; Binding Sites; Blotting, Western; DNA; Glycine; Glycoproteins; Humans; Molecular Sequence Data; Molecular Weight; Mutation; Oligonucleotide Probes; Plasminogen Activators; Plasminogen Inactivators; Serine; Threonine; Tissue Plasminogen Activator | 1989 |
Threonine phosphorylation is associated with mitosis in HeLa cells.
Topics: Antibodies; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Interphase; Mitosis; Phosphorylation; Serine; Threonine; Tyrosine | 1989 |
SPXX, a frequent sequence motif in gene regulatory proteins.
Topics: Amino Acid Sequence; Amino Acids; Animals; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Gene Expression Regulation; Histones; Models, Molecular; Molecular Sequence Data; Proline; Proteins; Serine; Threonine; Transcription Factors | 1989 |
Expression and site-specific mutagenesis of phospholamban. Studies of residues involved in phosphorylation and pentamer formation.
Topics: Amino Acid Sequence; Amino Acids; Animals; Calcium-Binding Proteins; Calmodulin; Cattle; Cell Line; Chlorocebus aethiops; Cysteine; DNA; Dogs; Kidney; Mutation; Phosphorylation; Protein Conformation; Protein Kinases; Serine; Threonine | 1989 |
Regulation of the insulin receptor kinase by hyperinsulinism.
Topics: Animals; Blotting, Western; Cell Line; Humans; Hyperinsulinism; Mice; Molecular Weight; Phosphorylation; Protein Kinases; Receptor, Insulin; Serine; Substrate Specificity; Threonine; Transfection; Tyrosine | 1989 |
Synthesis of phosphopeptides containing O-phosphoserine or O-phosphothreonine.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chromatography, Affinity; Mass Spectrometry; Phosphopeptides; Phosphoserine; Phosphothreonine; Serine; Threonine | 1989 |
SRTX-d, a new native peptide of the endothelin/sarafotoxin family.
Topics: Amino Acid Sequence; Animals; Aorta; Binding Sites; Chromatography, DEAE-Cellulose; Endothelins; Endothelium, Vascular; Molecular Sequence Data; Muscle Contraction; Peptides; Rabbits; Serine; Threonine; Vasoconstrictor Agents; Viper Venoms | 1989 |
Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation.
Topics: Alanine; Base Sequence; Camphor 5-Monooxygenase; Cloning, Molecular; Cytochrome P-450 Enzyme System; Escherichia coli; Genes, Bacterial; Kinetics; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Oxygen Consumption; Plasmids; Pseudomonas; Serine; Threonine; Valine | 1989 |
[Kinetic properties of L-serine dehydratase of the rat liver].
Topics: Animals; Hydrogen-Ion Concentration; L-Serine Dehydratase; Liver; Rats; Serine; Threonine | 1989 |
The expression of a highly expressed Bacillus subtilis gene is not reduced by introduction of multiple codons normally not present in such genes.
Topics: Bacillus subtilis; Codon; Gene Expression Regulation, Bacterial; Genes, Bacterial; RNA, Messenger; Serine; Spores, Bacterial; Threonine | 1989 |
Phospholamban phosphorylation in intact ventricles. Phosphorylation of serine 16 and threonine 17 in response to beta-adrenergic stimulation.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Calcium-Binding Proteins; Female; Guinea Pigs; Heart Ventricles; Isoproterenol; Macromolecular Substances; Male; Molecular Sequence Data; Myocardium; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphothreonine; Receptors, Adrenergic, beta; Serine; Threonine; Trypsin | 1989 |
The E7 protein of human papillomavirus type 16 is phosphorylated by casein kinase II.
Topics: Amino Acid Sequence; Casein Kinases; Heparin; Molecular Sequence Data; Oncogene Proteins, Viral; Papillomaviridae; Papillomavirus E7 Proteins; Peptide Fragments; Peptide Mapping; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Sequence Homology, Nucleic Acid; Serine; Threonine | 1989 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |
beta-Amyloid precursor is a PEST protein.
Topics: Amino Acid Sequence; Amyloid; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain Chemistry; Calpain; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Protease Inhibitors; Protein Precursors; Rats; Serine; Threonine | 1989 |
Differential regulation of oncogenic and cellular p185 by serine/threonine kinases.
Topics: Cell Division; Cell Line; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Membrane Proteins; Mutation; Oncogene Proteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor, ErbB-2; Serine; Tetradecanoylphorbol Acetate; Threonine | 1989 |
Properties of a Na+-coupled serine-threonine transport system in Escherichia coli.
Topics: Amino Acid Transport Systems; Biological Transport; Carrier Proteins; Escherichia coli; Kinetics; Protons; Serine; Sodium; Threonine | 1987 |
Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII heavy
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites, Antibody; Binding, Competitive; Blood Coagulation; Factor VIII; Humans; Isoantibodies; Mice; Molecular Sequence Data; Peptides; Platelet Membrane Glycoproteins; Protein Conformation; Receptors, Cell Surface; Serine; Threonine | 1988 |
Molecular genetics of serine and threonine catabolism in Saccharomyces cerevisiae.
Topics: Cloning, Molecular; DNA Restriction Enzymes; Genes; Genes, Fungal; Genetic Complementation Test; L-Serine Dehydratase; Membrane Transport Proteins; Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Threonine Dehydratase; Transcription, Genetic | 1988 |
Characterization of insulin-stimulated microtubule-associated protein kinase. Rapid isolation and stabilization of a novel serine/threonine kinase from 3T3-L1 cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Centrifugation, Density Gradient; Chromatography; Cytosol; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Insulin; Kinetics; Mice; Microtubule-Associated Proteins; Molecular Weight; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase Inhibitors; Protein Kinases; Serine; Substrate Specificity; Threonine | 1988 |
Splanchnic substrate balance in malnourished patients during parenteral nutrition.
Topics: Adipose Tissue; Alanine; Amino Acids, Branched-Chain; Cystine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Lipids; Liver; Male; Mesentery; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Protein Biosynthesis; Protein-Energy Malnutrition; Serine; Splanchnic Circulation; Threonine; Tyrosine | 1985 |
Glutamic acid as a putative transmitter of the interhemispheric corticocortical connections in the rat.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Male; Rats; Rats, Inbred Strains; Serine; Threonine | 1986 |
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis.
Topics: Amino Acid Sequence; Caseins; Glutamates; Glutamic Acid; Half-Life; HeLa Cells; Humans; Proline; Proteins; Serine; Threonine | 1986 |
alpha-Glucan synthesis on a protein primer, uridine diphosphoglucose: protein transglucosylase I. Separation from starch synthetase and phosphorylase and a study of its properties.
Topics: Amino Acids; Chromatography; Electrophoresis, Polyacrylamide Gel; Glucans; Glucosyltransferases; Kinetics; Plant Proteins; Plants; Serine; Solanum tuberosum; Substrate Specificity; Threonine | 1986 |
Phosphorylation of protein tyrosine by human erythrocyte casein kinase A.
Topics: Angiotensin II; Ankyrins; Casein Kinases; Erythrocytes; Humans; Isoenzymes; Membrane Proteins; Peptides; Phosphorylation; Protein Kinases; Serine; Threonine; Tyrosine | 1986 |
[Studies on duck serum lipoproteins. VII. Studies on physical and chemical properties of HDL-apo C II].
Topics: Amino Acids; Animals; Apolipoprotein C-II; Apolipoproteins C; Chemical Phenomena; Chemistry, Physical; Ducks; Lipoproteins, HDL; Serine; Threonine | 1986 |
Effects of phosphorylation of light chain residues threonine 18 and serine 19 on the properties and conformation of smooth muscle myosin.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Cattle; Kinetics; Microscopy, Electron; Muscle, Smooth; Myosin Subfragments; Myosins; Phosphorylation; Potassium Chloride; Protein Conformation; Rabbits; Serine; Threonine; Turkeys; Viscosity | 1988 |
Virion assembly defect of polyomavirus hr-t mutants: underphosphorylation of major capsid protein VP1 before viral DNA encapsidation.
Topics: Defective Viruses; DNA, Viral; Mutation; Phosphorylation; Polyomavirus; Serine; Threonine; Viral Proteins; Viral Structural Proteins; Virion | 1985 |
Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.
Topics: Animals; Bradykinin; Cell Line; Drug Tolerance; Kinetics; Muscle, Smooth; Norepinephrine; Phosphatidic Acids; Phosphatidylinositols; Phosphorylation; Prazosin; Receptors, Adrenergic, alpha; Serine; Tetradecanoylphorbol Acetate; Threonine | 1987 |
The phosphorylation at Thr 124 of simian virus 40 large T antigen is crucial for its oligomerization.
Topics: Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; DNA Replication; DNA, Viral; Oncogene Proteins, Viral; Phosphorylation; Polymers; Serine; Simian virus 40; Threonine; Virus Replication | 1987 |
Regulation of the protein kinase activity of the human insulin receptor.
Topics: Enzyme Activation; Insulin; Phosphoprotein Phosphatases; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Threonine; Tyrosine | 1987 |
beta-Ethynylserine, an antimetabolite of L-threonine, from Streptomyces cattleya.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites; Chemical Phenomena; Chemistry; Chickens; Magnetic Resonance Spectroscopy; Pseudomonas aeruginosa; Serine; Streptomyces; Threonine | 1986 |
Sequential metabolic characteristics following portacaval shunt in rats.
Topics: Amino Acids; Animals; Body Weight; Glucagon; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1986 |
Phosphorylation of liver pyruvate kinase by Ca++/calmodulin-dependent protein kinase: characterization of two phosphorylation sites.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium; Calmodulin; Chromatography, High Pressure Liquid; Isoenzymes; Liver; Phosphorylation; Protein Kinases; Pyruvate Kinase; Rats; Serine; Threonine | 1986 |
A model study directed towards the preparation of nucleopeptides via H-phosphonate intermediates.
Topics: Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleoproteins; Organophosphonates; Peptide Fragments; Serine; Structure-Activity Relationship; Threonine; Tyrosine | 1987 |
Subcellular site of synthesis of the N-acetylgalactosamine (alpha 1-0) serine (or threonine) linkage in rat liver.
Topics: Acetylgalactosamine; Animals; Carbon Radioisotopes; Endoplasmic Reticulum; Galactosamine; Galactosyltransferases; Golgi Apparatus; Intracellular Membranes; Liver; N-Acetylgalactosaminyltransferases; Polypeptide N-acetylgalactosaminyltransferase; Rats; Serine; Threonine; Tritium; Uridine Diphosphate N-Acetylgalactosamine | 1987 |
Characterization of carrier-mediated transport systems for small neutral amino acids in human fibroblast lysosomes.
Topics: Alanine; Amino Acids; Biological Transport, Active; Fibroblasts; Humans; Kinetics; Lysosomes; Mathematics; Osmolar Concentration; Proline; Serine; Sodium Chloride; Threonine | 1987 |
Genetic characterization of a highly efficient alternate pathway of serine biosynthesis in Escherichia coli.
Topics: Alcohol Oxidoreductases; Culture Media; Escherichia coli; Glycine; Mutation; Phenotype; Serine; Threonine | 1987 |
EDTA-extractable proteins from calf lens fiber membranes are phosphorylated by Ca2+-phospholipid-dependent protein kinase.
Topics: Animals; Cattle; Edetic Acid; Electrophoresis; Eye Proteins; Lens, Crystalline; Membrane Proteins; Molecular Weight; Phosphorylation; Phosphothreonine; Protein Kinase C; Serine; Threonine | 1987 |
Behavior of L-threonine-degrading enzymes during liver regeneration.
Topics: Alcohol Oxidoreductases; Animals; Glycine; Glycine Hydroxymethyltransferase; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains; Serine; Threonine; Threonine Dehydratase; Turpentine | 1987 |
Hydrogen bonding between cytosine and peptides of threonine or serine: is it relevant to the origin of the genetic code?
Topics: Codon; Cytosine; Genetic Code; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligopeptides; Protein Conformation; Serine; Threonine | 1987 |
A kinetic method for distinguishing whether an enzyme has one or two active sites for two different substrates. Rat liver L-threonine dehydratase has a single active site for threonine and serine.
Topics: Animals; Binding Sites; Kinetics; Liver; Male; Mathematics; Rats; Rats, Inbred Strains; Serine; Substrate Specificity; Threonine; Threonine Dehydratase | 1987 |
Phosphorylation of synthetic random polypeptides by protein kinase P and other protein-serine (threonine) kinases and stimulation or inhibition of kinase activities by microbial toxins.
Topics: Adenosine Triphosphate; Bacterial Proteins; Casein Kinases; Caseins; In Vitro Techniques; Peptides; Phosphorylation; Polymyxin B; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Serine; Substrate Specificity; Threonine | 1988 |
Characterization of a novel L-serine transport system in Escherichia coli.
Topics: Alanine; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Culture Media; Escherichia coli; Glycine; Isoleucine; Kinetics; Potassium Cyanide; Serine; Threonine; Valine | 1988 |
Water solubilization of membrane proteins. Extensive derivatization with a novel polar derivatizing reagent.
Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Indicators and Reagents; Kinetics; Membrane Proteins; Models, Chemical; Serine; Solubility; Solvents; Threonine; Tyrosine; Water | 1988 |
Site-directed mutagenesis in the DNA linking site of bacteriophage phi 29 terminal protein: isolation and characterization of a Ser232----Thr mutant.
Topics: Bacteriophages; DNA-Binding Proteins; DNA, Viral; Mutation; Plasmids; Serine; Threonine; Viral Proteins | 1988 |
Sodium-dependent transport of neutral amino acids by whole cells and membrane vesicles of Streptococcus bovis, a ruminal bacterium.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Cell Membrane; Glucose; Membrane Potentials; Rumen; Serine; Sodium; Streptococcus; Threonine | 1988 |
The molecular evolution of genes and proteins: a tale of two serines.
Topics: Amino Acid Sequence; Binding Sites; Biological Evolution; Codon; Cysteine; Enzymes; Esterases; Exons; Molecular Sequence Data; Mutation; Peptide Hydrolases; Serine; Threonine | 1988 |
Epidermal growth factor receptor threonine and serine residues phosphorylated in vivo.
Topics: Amino Acid Sequence; Animals; Blood; Cell Line; Chromatography, High Pressure Liquid; ErbB Receptors; Peptide Mapping; Phosphorylation; Serine; Threonine | 1988 |
Some characteristics of threonine transport across the blood-brain barrier of the rat.
Topics: Amino Acids; Amino Acids, Cyclic; Aminoisobutyric Acids; Animals; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Brain; Cysteine; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Serine; Sodium; Threonine | 1988 |
Study of the phosphorylatable light chains of skeletal and gizzard myosins by nuclear magnetic resonance spectroscopy.
Topics: Animals; Chickens; Gizzard, Avian; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Muscle, Smooth; Myosins; Phosphorylation; Protein Conformation; Rabbits; Serine; Sodium Chloride; Threonine | 1988 |
Phosphorylation of the 20,000-Da myosin light chain isoforms of arterial smooth muscle by myosin light chain kinase and protein kinase C.
Topics: Adenosine Triphosphate; Animals; Arteries; Binding Sites; In Vitro Techniques; Magnesium; Muscle, Smooth, Vascular; Myosin Subfragments; Myosin-Light-Chain Kinase; Myosins; Peptide Fragments; Phosphorylation; Protein Kinase C; Serine; Swine; Threonine | 1988 |
Comparison of phosphorylation sites in protamines between protein kinase C and cAMP-dependent protein kinase.
Topics: Amino Acid Sequence; Binding Sites; Clupeine; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Protamines; Protein Kinase C; Protein Kinases; Serine; Threonine | 1988 |
Phosphorylation of a chromaffin granule-binding protein by protein kinase C.
Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Annexins; Calcium; Carrier Proteins; Chromaffin Granules; Chromaffin System; Diglycerides; Membrane Proteins; Phosphatidylserines; Phosphorylation; Protein Kinase C; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; Threonine | 1985 |
Structural relatedness of three ion-transport adenosine triphosphatases around their active sites of phosphorylation.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kidney Medulla; Phosphorylation; Plants; Pronase; Protein Conformation; Serine; Swine; Threonine; Trypsin | 1985 |
A minor species of a type I casein kinase from yeast phosphorylating threonine residues of protein substrate.
Topics: Adenosine Triphosphate; Casein Kinases; Caseins; Molecular Weight; Phosphorylation; Phosvitin; Protein Kinases; Saccharomyces cerevisiae; Serine; Substrate Specificity; Threonine | 1985 |
Mechanisms of chain initiation in the biosynthesis of connective tissue polysaccharides.
Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Asparagine; Connective Tissue; Endoplasmic Reticulum; Golgi Apparatus; Hyaluronic Acid; Keratan Sulfate; Oligopeptides; Pentosyltransferases; Polysaccharides; Proteoglycans; Serine; Substrate Specificity; Threonine; UDP Xylose-Protein Xylosyltransferase; Xylose | 1985 |
Respiratory syncytial virus polypeptides. IV. The oligosaccharides of the glycoproteins.
Topics: Asparagine; Glycoproteins; Glycoside Hydrolases; HeLa Cells; Humans; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Monensin; Oligosaccharides; Respiratory Syncytial Viruses; Serine; Threonine; Tunicamycin; Viral Proteins | 1985 |
Protein phosphorylation of beta-glucuronidase in human lung cancer--identification of serine- and threonine-phosphates.
Topics: Adenocarcinoma; Chemical Phenomena; Chemistry; Electrophoresis, Polyacrylamide Gel; Glucuronidase; Humans; Hydrolysis; Immunodiffusion; Liver; Lung; Lung Neoplasms; Phosphorylation; Phosphoserine; Phosphothreonine; Serine; Threonine | 1985 |
Phosphoprotein phosphatase inhibitor-2 is phosphorylated at both serine and threonine residues in mouse diaphragm.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Diaphragm; Immunosorbent Techniques; Male; Mice; Molecular Weight; Muscle Proteins; Muscles; Phosphorylation; Proteins; Serine; Threonine | 1985 |
A type-1 casein kinase from yeast phosphorylates both serine and threonine residues of casein. Identification of the phosphorylation sites.
Topics: Binding Sites; Casein Kinases; Caseins; Phosphorylation; Protein Kinases; Saccharomyces cerevisiae; Serine; Substrate Specificity; Threonine | 1985 |
Structure and expression of adenovirus type 12 E1B 58K protein in infected and transformed cells: studies using antibodies directed against a synthetic peptide.
Topics: Adenoviruses, Human; Amino Acid Sequence; Animals; Antigens, Viral, Tumor; Cell Line; Cell Transformation, Viral; Cricetinae; Humans; Phosphorylation; Protein Biosynthesis; Serine; Threonine; Viral Proteins | 1985 |
Rat liver L-threonine deaminase: properties and purification.
Topics: Animals; Chromatography, Gel; Cysteine; Hydrogen-Ion Concentration; Liver; Male; Molecular Weight; Protein Conformation; Rats; Rats, Inbred Strains; Serine; Substrate Specificity; Threonine; Threonine Dehydratase | 1985 |
Protein phosphorylation and activation of platelets by wheat germ agglutinin.
Topics: Acetylglucosamine; Amino Acids; Electrophoresis, Polyacrylamide Gel; Humans; Lectins; Molecular Weight; Phosphorylation; Platelet Aggregation; Proteins; Serine; Threonine; Thrombin; Wheat Germ Agglutinins | 1985 |
On the structure of the acyl linkage and the function of fatty acyl chains in the influenza virus haemagglutinin and the glycoproteins of Semliki Forest virus.
Topics: Esters; Fatty Acids; Glycoproteins; Hemagglutinins, Viral; Hemolysis; Hydrolysis; Lipoproteins; Membrane Fusion; Orthomyxoviridae; Protein Processing, Post-Translational; Semliki forest virus; Serine; Structure-Activity Relationship; Threonine; Viral Envelope Proteins | 1985 |
Evidence for unique homologous peptide sequences around the glycosylated seryl and threonyl residues in polysialoglycoproteins isolated from the unfertilized eggs of the Pacific salmon Oncorhynchus keta.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carbohydrate Sequence; Carbohydrates; Female; Glycopeptides; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mass Spectrometry; Ovum; Salmon; Serine; Sialoglycoproteins; Threonine | 1985 |
A new Na+-independent transport system for dipolar amino acids apparently corresponding to systems persisting after erythrocyte maturation in some mammalian genotypes.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Columbidae; Cysteine; Erythrocyte Aging; Erythrocytes; Horses; Kinetics; Serine; Sheep; Sodium; Species Specificity; Threonine | 1985 |
p-Cresol formation by cell-free extracts of Clostridium difficile.
Topics: Butyrates; Clostridium; Cresols; Decarboxylation; Dithionite; Ketoglutaric Acids; Phenylacetates; Pyruvates; Serine; Threonine | 1985 |
Decrease of plasma sulfur amino acids in essential hypertension.
Topics: Adult; Aged; Amino Acids, Sulfur; Blood Pressure; Female; Humans; Hypertension; Male; Methionine; Middle Aged; Serine; Taurine; Threonine | 1985 |
Antigenic and C-substance activities of related glycopeptides from fungal, parasitic and vegetable sources.
Topics: Alanine; Antigen-Antibody Reactions; Antigens; Ascaris; Aspartic Acid; Aspergillus; C-Reactive Protein; Cross Reactions; Epidermophyton; Epitopes; Galactose; Glutamates; Glycopeptides; Mannose; Peptides; Plants; Polysaccharides, Bacterial; Serine; Skin Tests; Threonine; Trichophyton | 1971 |
[Biochemical aspects of the effect of L-dopa in patients with Parkinson's disease].
Topics: Cysteine; Cystine; Dihydroxyphenylalanine; Female; Glycine; Humans; Male; Methionine; Parkinson Disease; Serine; Threonine; Time Factors | 1972 |
Studies on the enzymes involved in the biosynthesis of cyclo-tris (N-2,3-dihydroxybenzoyl-L-seryl) in Escherichia coli: kinetic properties of the L-serine-activating enzyme.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Anti-Bacterial Agents; Drug Stability; Enzyme Induction; Escherichia coli; Ethylmaleimide; Glycine; Gramicidin; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Phosphates; Phosphorus Radioisotopes; Proline; Serine; Threonine; Time Factors; Tritium; Tyrosine | 1973 |
Accumulation of neutral amino acids by Streptococcus faecalis. Energy coupling by a proton-motive force.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Biological Transport, Active; Carbon Radioisotopes; Carboxylic Acids; Cycloserine; Dicyclohexylcarbodiimide; Energy Metabolism; Enterococcus faecalis; Glycine; Glycolysis; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Models, Biological; Mutation; Polycyclic Compounds; Potassium; Serine; Sodium; Threonine; Time Factors; Valinomycin | 1973 |
In vitro and in vivo phosphorylation of myelin basic protein by exogenous and endogenous adenosine 3':5'-monophosphate-dependent protein kinases in brain.
Topics: Animals; Brain; Brain Chemistry; Cattle; Cyclic AMP; Electrophoresis, Disc; Electrophoresis, Paper; Enzyme Activation; Histones; Magnesium; Male; Myelin Basic Protein; Myelin Sheath; Organophosphorus Compounds; Phosphates; Phospholipids; Phosphorus; Phosphorus Radioisotopes; Protein Kinases; Rats; Serine; Structure-Activity Relationship; Threonine | 1974 |
Studies on the elimination reaction of D-amino acid oxidase with -amino- -chlorobutyrate. Further evidence for abstraction of substrate -hydrogen as a proton.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Apoproteins; Catalysis; Chlorine; D-Amino-Acid Oxidase; Deuterium; Hydrogen; Isomerism; Keto Acids; Kidney; Kinetics; Osmolar Concentration; Oxidation-Reduction; Oxygen Consumption; Protons; Serine; Spectrophotometry; Swine; Temperature; Threonine; Tritium | 1973 |
Interconversion of glycine and serine in a synaptosome fraction isolated from the spinal cord, medulla oblongata, telencephalon, and cerebellum of the rat.
Topics: Alanine; Animals; Aspartic Acid; Carbon Radioisotopes; Cerebellum; Female; Glutamates; Glutamine; Glycine; In Vitro Techniques; Medulla Oblongata; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Synaptosomes; Telencephalon; Threonine | 1973 |
The effect of changes in external salinity on the non-protein nitrogenous constituents of parietal muscle from Agonus cataphractus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Body Water; Ethionine; Fishes; Glutamates; Glutamine; Glycine; Lysine; Methionine; Muscles; Nitrogen; Osmolar Concentration; Potassium; Seawater; Serine; Sodium; Sodium Chloride; Taurine; Threonine | 1974 |
[Relation between gamma-aminobutyric acid and tyrosine metabolism and changes in the brain and liver amino acid content in intact and adrenalectomized rats].
Topics: Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Liver; Lysine; Male; Rats; Serine; Stimulation, Chemical; Threonine; Tyrosine | 1972 |
Free amino acids in the photoreceptor cells of the frog retina.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Dansyl Compounds; Fluorescence; gamma-Aminobutyric Acid; Glutamine; Glycine; Organ Specificity; Photoreceptor Cells; Rana temporaria; Retina; Serine; Taurine; Threonine; Tritium | 1974 |
The energy-yielding reactions of Peptococcus prévotii, their behaviour on starvation and the role and regulation of threonine dehydratase.
Topics: Acyltransferases; Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Anaerobiosis; Binding Sites; Energy Metabolism; Hot Temperature; Hydro-Lyases; Hydrogen-Ion Concentration; Keto Acids; Kinetics; L-Serine Dehydratase; NADH, NADPH Oxidoreductases; Nitrogen; Oxidation-Reduction; Peptococcus; Pyridoxal Phosphate; Serine; Starvation; Threonine | 1974 |
Comparison of the amino acid sequences of the variable regions of light chains derived from two homogeneous rabbit anti-pneumococcal antibodies.
Topics: Aconitic Acid; Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Bacterial; Asparagine; Aspartic Acid; Autoanalysis; Chromatography, Gel; Electrophoresis, Paper; Glutamates; Glycine; Hydrolysis; Immunoglobulin Fragments; Rabbits; Serine; Streptococcus pneumoniae; Threonine; Tyrosine; Valine | 1974 |
The presence of two types of carbohydrate-amino acid linkage in the same glycoprotein.
Topics: Aspartic Acid; Chromatography, Paper; Galactose; gamma-Globulins; Glycoproteins; Hexoses; Mannose; Multiple Myeloma; Neuraminic Acids; Peptides; Serine; Threonine | 1967 |
The position of various cleavages of rabbit immunoglobulin G.
Topics: Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Bromine; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyanides; Cysteine; gamma-Globulins; Glutamates; Leucine; Lysine; Pepsin A; Proline; Rabbits; Serine; Sulfhydryl Compounds; Threonine; Trypsin | 1968 |
[Study on glycoproteins. Demonstration of the O-seryl and O-threonyl-N-acetylgalactosaminidic bonds in the gamma A globulins of human milk].
Topics: Amino Acids; Aspartic Acid; Autoanalysis; Colorimetry; Female; Galactosidases; gamma-Globulins; Glucosamine; Glycoproteins; Humans; Milk, Human; Protein Binding; Serine; Threonine | 1968 |
A blocked N-terminal residue in the light chain of rabbit immunoglobulin G.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Chromatography, Paper; Electrophoresis; gamma-Globulins; Glutamates; Glycine; Hydrogen-Ion Concentration; Leucine; Peptide Hydrolases; Rabbits; Serine; Threonine; Valine | 1968 |
Argininosuccinic aciduria in hereditary hair diseases.
Topics: Adolescent; Adult; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Chromatography, Paper; Cystinuria; Female; Glutamates; Glutamine; Glycine; Hair; Histidine; Humans; Infant; Lysine; Male; Middle Aged; Serine; Skin Diseases; Threonine; Tyrosine; Valine | 1968 |
Na+-dependent transport of threonine in Brevibacterium flavum.
Topics: Amino Acids; Arthrobacter; Bacillus subtilis; Biological Transport, Active; Brevibacterium; Enterobacter; Enterococcus faecalis; Escherichia coli; Ions; Micrococcus; Pseudomonas aeruginosa; Serine; Serratia marcescens; Sodium; Stimulation, Chemical; Threonine | 1973 |
NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Cell-Free System; Culture Media; Dinitrophenols; Enterococcus faecalis; Folic Acid; Glutamates; Glycine; Methionine; Ribosomes; Serine; Solubility; Threonine | 1973 |
L-threonine deaminase in marine planktonic algae. IV. Studies of substrate specificity and inhibition from substrate analogs. Evidence for additional L-serine deaminase activity in the cryptophyte Chroomonas salina.
Topics: Ammonium Chloride; Deamination; Dithiothreitol; Edetic Acid; Eukaryota; Homoserine; Hydro-Lyases; Isoleucine; L-Serine Dehydratase; Phytoplankton; Plankton; Plant Extracts; Potassium Chloride; Serine; Species Specificity; Stereoisomerism; Threonine; Valine; Water Microbiology | 1973 |
Comparative biochemistry of keratosulfates.
Topics: Animals; Aspartic Acid; Biochemical Phenomena; Biochemistry; Cartilage; Cattle; Cornea; Electrophoresis; Fishes; Glutamates; Glycosaminoglycans; Hexosamines; In Vitro Techniques; Physiology, Comparative; Poultry; Proline; Serine; Sharks; Threonine | 1965 |
[Further studies on bovine neuraminic acid-containing mucoids].
Topics: Amniotic Fluid; Animals; Cattle; Erythrocytes; Female; Glutamates; Hexosamines; Mucoproteins; Neuraminic Acids; Pregnancy; Pregnancy, Animal; Serine; Threonine | 1965 |
The protein-polysaccharide linkages in some proteoglycans.
Topics: Animals; Chemical Phenomena; Chemistry; Dogs; Glycosaminoglycans; Humans; Mucopolysaccharidosis IV; Mucoproteins; Serine; Submandibular Gland; Threonine; Trachea | 1966 |
Characterization of urinary peptoglycans in Morquio's disease.
Topics: Amino Acids; Animals; Chondroitin; Chromatography; Glycosaminoglycans; Mucopolysaccharidosis IV; Peptides; Serine; Sulfates; Threonine | 1968 |
The preparation and properties of a glycoprotein from pigs' blood platelets.
Topics: Amino Acids; Animals; Aspartic Acid; Blood Platelets; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Fucose; Galactose; Glucosamine; Glutamates; Glycoproteins; Glycosaminoglycans; Hexosamines; Hyaluronoglucosaminidase; Neuraminic Acids; Neuraminidase; Papain; Serine; Swine; Threonine; Uronic Acids | 1968 |
Urinary amino acids in storage disorders: mucopolysaccharidosis, Gaucher's disease and metachromatic leucodystrophy.
Topics: Adolescent; Adult; Amino Acids; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Diffuse Cerebral Sclerosis of Schilder; Female; Gaucher Disease; Glycolipids; Glycoproteins; Glycosaminoglycans; Humans; Intellectual Disability; Lysosomes; Male; Mucopolysaccharidoses; Mucopolysaccharidosis IV; Retinitis Pigmentosa; Serine; Threonine; Tryptophan | 1969 |
Sulfated glycopeptides and glycosaminoglycan peptides isolated from intestinal mucosae of rabbit.
Topics: Amino Acids; Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Colon; Electrophoresis; Fucose; Galactose; Glycoproteins; Glycosaminoglycans; Hexosamines; Hexoses; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Small; Light; Methods; Neuraminic Acids; Organ Specificity; Peptides; Proline; Rabbits; Rotation; Serine; Spectrophotometry; Sulfates; Threonine; Ultracentrifugation; Uronic Acids | 1969 |
[Phosphoproteins of plasma membranes from rat liver. Phosphorylation by (gamma-32P)ATP].
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Autoradiography; Biological Transport, Active; Cell Membrane; Cold Temperature; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Liver; Magnesium; Male; Ouabain; Phosphates; Phosphorus Isotopes; Potassium; Proteins; Rats; Serine; Sodium; Temperature; Threonine | 1970 |
[Influence of changes in urinary pH on the excretion of amino acids from the isolated perfused rat kidney].
Topics: Alanine; Amino Acids; Animals; Arginine; Diffusion; Glycine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Leucine; Lysine; Perfusion; Rats; Serine; Threonine; Tyrosine; Urine; Valine | 1967 |
The carbohydrate-peptide linkage region of keratan sulfate from whale cartilage.
Topics: Animals; Carbohydrates; Cartilage; Cetacea; Glycosaminoglycans; Hexosamines; Keratins; Peptides; Serine; Sodium Hydroxide; Sulfuric Acids; Threonine | 1970 |
Human cardiac myosin. Biochemical and structural characterization.
Topics: Adenosine Triphosphatases; Amino Acids; Animals; Chromatography, Gel; Dogs; Heart Valve Prosthesis; Heart Ventricles; Humans; Molecular Weight; Muscle Proteins; Papillary Muscles; Proline; Rheumatic Heart Disease; Serine; Sulfhydryl Compounds; Threonine; Ultracentrifugation; Valine; Viscosity | 1970 |
Isolation, characterization, and partial structure of peptido galactomannans from the yeast form of Cladosporium werneckii.
Topics: Acetates; Amino Acids; Borates; Chemical Precipitation; Chromatography, Gas; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Ethanol; Galactose; Glycosaminoglycans; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Mannose; Methylation; Mitosporic Fungi; Peptide Hydrolases; Peptides; Phosphates; Quaternary Ammonium Compounds; Saccharomyces; Serine; Sodium; Solubility; Species Specificity; Threonine; Trichophyton | 1970 |
Phosphorylation of bovine brain Na + , K + -stimulated ATP phosphohydrolase by adenosine ( 32 P)triphosphate studied by a rapid-mixing technique.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Brain; Cattle; Enzyme Activation; Hydrolysis; Kinetics; Microsomes; Ouabain; Oxidative Phosphorylation; Phospholipids; Phosphoproteins; Phosphorus Isotopes; Potassium; Serine; Sodium; Temperature; Threonine | 1972 |
Elimination and sulfite addition as a means of localization and identification of substituted seryl and threonyl residues in proteins and proteoglycans.
Topics: Alanine; Alkylation; Aminobutyrates; Animals; Binding Sites; Cartilage; Caseins; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Ion Exchange; Glucagon; Glycoproteins; Glycosaminoglycans; Mucins; Optical Rotatory Dispersion; Oxidation-Reduction; Phosphoproteins; Proteins; Serine; Submandibular Gland; Sulfites; Sulfones; Sulfonic Acids; Sulfur Isotopes; Swine; Threonine; Trypsin | 1972 |
O-sulfate esters of hydroxy amino acids in hydrolyzates of proteoglycans.
Topics: Amino Acids; Animals; Cartilage; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Esters; Glycosaminoglycans; Hydrochloric Acid; Hydrolysis; Hydroxyproline; Methods; Potassium; Serine; Sulfates; Sulfuric Acids; Threonine; Tyrosine | 1972 |
Carbohydrate-peptide linkages in glycoproteins and mucopolysaccharides from brain.
Topics: Acetates; Animals; Asparagine; Borohydrides; Brain; Cattle; Chondroitin; Chromatography, Gel; Galactosamine; Glucosamine; Glycoproteins; Glycosaminoglycans; Heparitin Sulfate; Molecular Conformation; Protein Binding; Rabbits; Rats; Serine; Sulfuric Acids; Threonine | 1972 |
Some characteristics of the p-chlorophenylalanine-induced cataract.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Cataract; Chromatography, Gas; Crystallins; Electrophoresis; Female; Fenclonine; Glutathione; Glycine; Lens, Crystalline; Male; Ornithine; Rats; Serine; Threonine | 1973 |
On the nature and function of the lipopolysaccharide receptor from human erythrocytes.
Topics: Aspartic Acid; Binding Sites; Cell Membrane; Erythrocytes; Escherichia coli; Galactosemias; Glutamates; Glycoproteins; Humans; Lipopolysaccharides; Neuraminic Acids; Neuraminidase; Peptides; Serine; Threonine; Vibrio cholerae | 1973 |
Structure of amino acyl oligonucleotides from T-1 ribonuclease digests of soluble ribonucleic acid charged with serine, glycine, threonine, and alanine.
Topics: Alanine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Glycine; Phosphoric Monoester Hydrolases; Polynucleotides; Ribonucleases; RNA, Transfer; Serine; Spectrophotometry; Threonine; Venoms | 1966 |
Amino acid uptake in isolated chick embryo heart cells.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Chick Embryo; Glycine; Heart; Histidine; In Vitro Techniques; Insulin; Leucine; Methionine; Microbial Collagenase; Myocardium; Oxygen Consumption; Proline; Protein Biosynthesis; Serine; Threonine | 1969 |
Regulatory significance of transfer RNA charging levels. I. Measurements of charging levels in livers of chow-fed rats, fasting rats, and rats fed balanced or imbalanced mixtures of amino acids.
Topics: Amino Acids; Animals; Cysteine; Diet; Fasting; Ligases; Liver; Male; Periodic Acid; Rats; RNA, Transfer; Serine; Threonine; Tryptophan | 1969 |
An investigation of the products of an enzymic hydrolysis of collagens.
Topics: Amides; Amino Acid Sequence; Amino Acids; Animals; Autoanalysis; Cattle; Chromatography, Gel; Collagen; Dipeptidases; Fishes; Gelatin; Hydrogen-Ion Concentration; Leucyl Aminopeptidase; Male; Microbial Collagenase; Papain; Peptides; Serine; Skin; Sodium Chloride; Solubility; Threonine | 1969 |
Glycoenzymes: a note on the role for the carbohydrate moieties.
Topics: Amino Acids; Amylases; Aspergillus; Carbohydrates; Catalysis; Cold Temperature; Drug Stability; Oxidation-Reduction; Periodic Acid; Serine; Threonine | 1970 |
Isolation of amino acid acceptor RNA from purified avian myeloblastosis virus.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Avian Leukosis Virus; Centrifugation, Density Gradient; Chick Embryo; Glycine; In Vitro Techniques; Isoleucine; Ligases; Methionine; Phenylalanine; Proline; Ribonucleases; RNA, Transfer; RNA, Viral; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
The extracellular nuclease activity of Micrococcus sodonensis. IV. Physical studies, characterization as a glycoprotein and involvement with the cell wall.
Topics: Amino Acids; Animals; Cell Wall; Chromatography, Paper; Galactose; Glucosamine; Glucose; Glycine; Glycoproteins; Immunodiffusion; Micrococcus; Molecular Weight; Phosphoric Monoester Hydrolases; Proline; Rabbits; Rhamnose; Ribonucleases; Serine; Threonine; Time Factors; Tryptophan; Ultracentrifugation | 1970 |
Adenosine 3',5'-cyclic phosphate-dependent and independent histone kinases from rat liver.
Topics: Adenine Nucleotides; Animals; Autoradiography; Chemical Phenomena; Chemistry; Chromatography; Cyclic AMP; Drug Stability; Histones; Hot Temperature; Liver; Phosphorus Isotopes; Phosphotransferases; Protein Denaturation; Rats; Serine; Threonine | 1970 |
Enzymatic phosphorylation of protein of rat liver chromatin by (gamma-32P) ATP in vitro.
Topics: Adenosine Triphosphate; Animals; Chemical Phenomena; Chemistry; Chromosomes; Cyclic AMP; Edetic Acid; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Magnesium; Manganese; Nucleoproteins; Phosphorus Isotopes; Protein Denaturation; Protein Hydrolysates; Rats; Serine; Threonine | 1971 |
Adenosine 3',5'-monophosphate-dependent and -independent protein phosphokinase isoenzymes from mammary gland.
Topics: Adenine Nucleotides; Amino Acids; Animals; Binding Sites; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Cobalt; Cyclic AMP; Cyclic GMP; Cytoplasm; Cytosine Nucleotides; Drug Stability; Electrophoresis; Enzyme Activation; Female; Histones; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lactation; Magnesium; Mammary Glands, Animal; Peptides; Phosphopeptides; Phosphorus Isotopes; Phosphotransferases; Pregnancy; Proteins; Rats; Serine; Threonine; Trypsin; Uracil Nucleotides | 1971 |
Rat liver cytosol phosphoprotein: purification and enzymatic phosphorylation and dephosphorylation.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Caseins; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Electrophoresis; Guanine Nucleotides; Liver; Microsomes, Liver; Mitochondria, Liver; Phosphoric Monoester Hydrolases; Phosphorus; Phosphorus Isotopes; Phosphotransferases; Proteins; Rats; Serine; Threonine | 1971 |
The carbohydrate sequence of the glycopeptide chains of human transferrin.
Topics: Asparagine; Carbohydrates; Chromatography, DEAE-Cellulose; Chromatography, Gas; Chromatography, Gel; Disaccharides; Formaldehyde; Formates; Galactose; Galactosidases; Glycine; Glycopeptides; Glycoside Hydrolases; Humans; Hydrolysis; Mannose; Methylation; Neuraminic Acids; Periodic Acid; Serine; Threonine; Transferrin | 1971 |
Glycopeptides from silk fibroin of Bombyx mori.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Bombyx; Boron Compounds; Chromatography, Gel; Chromatography, Ion Exchange; Fibroins; Glucosamine; Glycine; Glycopeptides; Hydrolysis; Mannose; Molecular Weight; Oxidation-Reduction; Peptide Hydrolases; Peptides; Periodic Acid; Serine; Thiocyanates; Threonine; Trypsin | 1971 |
Heterogeneity of protein-polysaccharides of porcine articular cartilage. The chondroitin sulphate proteins associaterd with collagen.
Topics: Acetates; Animals; Cartilage, Articular; Chondroitin; Collagen; Galactosamine; Glycoproteins; Glycosaminoglycans; Hexosamines; Hexoses; Hydroxyproline; Microbial Collagenase; Pentoses; Serine; Sulfates; Swine; Threonine; Urea; Uronic Acids | 1971 |
Characterization of porcine malate dehydrogenase. I. An active center peptide.
Topics: Acetamides; Amino Acid Sequence; Animals; Binding Sites; Carbon Isotopes; Carboxypeptidases; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cysteine; Dansyl Compounds; Glycine; Histidine; Iodoacetates; Kinetics; Malate Dehydrogenase; Methionine; Mitochondria, Muscle; Myocardium; NAD; Peptides; Pronase; Serine; Swine; Threonine | 1971 |
Alterations of free amino acids concentrations in cat brain induced by rapid eye movement sleep deprivation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cats; Caudate Nucleus; Cysteine; Frontal Lobe; Glutamates; Glycine; Hippocampus; Histidine; Lysine; Male; Occipital Lobe; Reticular Formation; Serine; Sleep Deprivation; Sleep, REM; Thalamus; Threonine; Tyrosine | 1971 |
Phosphoprotein phosphatases from rat cerebral cortex. Subcellular distribution and characterization.
Topics: Adenosine Triphosphate; Animals; Cattle; Centrifugation, Density Gradient; Cerebral Cortex; Chromatography, DEAE-Cellulose; Cytoplasm; Enzyme Activation; Histones; Isotope Labeling; Male; Manganese; Microsomes; Mitochondria; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Phosphotransferases; Protamines; Rats; Serine; Subcellular Fractions; Surface-Active Agents; Synaptic Membranes; Threonine | 1972 |
Enzymatic phosphorylation of serine.
Topics: Adenosine Triphosphate; Ammonium Sulfate; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cobalt; Cysteine; Diphosphates; Drug Stability; Homoserine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Phosphotransferases; Propionibacterium; Protamines; Serine; Species Specificity; Stereoisomerism; Structure-Activity Relationship; Temperature; Thermodynamics; Threonine | 1972 |
Phosphorylation of ribosomal proteins of Escherichia coli by protein kinase from rabbit skeletal muscle.
Topics: Acrylamides; Adenosine Triphosphate; Ammonium Chloride; Animals; Autoradiography; Bacterial Proteins; Cyclic AMP; Electrophoresis; Enzyme Activation; Escherichia coli; Kinetics; Molecular Weight; Muscles; Phosphoproteins; Phosphorus Isotopes; Phosphotransferases; Rabbits; Ribosomes; Serine; Sodium Dodecyl Sulfate; Threonine; Urea | 1972 |
The release of amino acids from the hemisected spinal cord during stimulation.
Topics: Amino Acids; Aminobutyrates; Animals; Anura; Aspartic Acid; Bufo bufo; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Electric Stimulation; Glutamates; Glycine; In Vitro Techniques; Leucine; Perfusion; Rana temporaria; Serine; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission; Threonine; Tritium | 1972 |
Phosphorylation of ribosomal proteins by substrate-specific protein kinases from rabbit reticulocytes.
Topics: Adenosine Triphosphate; Animals; Blood Proteins; Caseins; Cell Fractionation; Chromatography, DEAE-Cellulose; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; Histones; Molecular Weight; Oxidative Phosphorylation; Phosphorus Isotopes; Phosphotransferases; Rabbits; Reticulocytes; Ribosomes; Serine; Threonine | 1973 |
Erythrocyte protein phosphorylation.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Blood Proteins; Calcium; Cell Membrane; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Humans; Osmolar Concentration; Phosphoric Acids; Phosphorus Isotopes; Phosphotransferases; Potassium; Proteins; Serine; Sodium; Sodium Dodecyl Sulfate; Threonine | 1973 |
Reciprocal induction and repression of serine dehydratase and phosphoglycerate dehydrogenase by proteins and dietary-essential amino acids in rat liver.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Caseins; Dietary Proteins; Egg Proteins; Enzyme Induction; Enzyme Repression; Glutens; Glyceric Acids; L-Serine Dehydratase; Liver; Male; Methionine; Models, Biological; NAD; Organophosphorus Compounds; Protein Biosynthesis; Rats; Serine; Threonine; Tryptophan; Valine | 1973 |
A study of the phosphate linkages in phosphomannan in cell walls of Saccharomyces cerevisiae.
Topics: Acids; Alkalies; Boric Acids; Cell Wall; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis; Hydrolysis; Mannose; Periodic Acid; Phosphates; Polysaccharides; Pronase; Saccharomyces cerevisiae; Serine; Threonine | 1972 |
Phosphorylation of muscle membranes: identification of a membrane-bound protein kinase.
Topics: Adenosine Triphosphate; Animals; Cell Fractionation; Cell Membrane; Cyclic AMP; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Magnesium; Molecular Weight; Muscles; Oxidative Phosphorylation; Peptides; Phosphorus Radioisotopes; Protein Kinases; Rats; Serine; Threonine | 1973 |
Phosphorylation of adenohypophyseal plasma membranes and properties of associated protein kinase.
Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Calcium; Cell Membrane; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Histones; Kinetics; Magnesium; Osmolar Concentration; Phosphoproteins; Phosphorus Radioisotopes; Pituitary Gland; Protein Kinase Inhibitors; Protein Kinases; Rats; Serine; Solubility; Surface-Active Agents; Threonine | 1974 |
Nuclear protein kinases. Evidence for their heterogeneity, tissue specificity, substrate specificities, and differential responses to cyclic adenosine 3':5'-monophosphate.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Caseins; Cattle; Cell Nucleus; Chromatography, Ion Exchange; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Histones; Liver; Organ Specificity; Organophosphorus Compounds; Phosphoproteins; Phosphoric Diester Hydrolases; Phosphorus Radioisotopes; Protein Kinases; Serine; Threonine; Ultrafiltration | 1974 |
Phosphorylation of acid-soluble nucleolar proteins of Novikoff hepatoma ascites cells in vivo.
Topics: Amino Acids; Animals; Ascitic Fluid; Autoradiography; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nucleolus; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Liver Neoplasms; Male; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Organophosphorus Compounds; Peptide Fragments; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Pronase; Rats; Serine; Solubility; Threonine | 1974 |
Partial characterization of the sexual agglutination factor from Hansenula wingei Y-2340 type 5 cells.
Topics: Agglutination Tests; Amino Acids; Ascomycota; Binding Sites; Carbohydrates; Glycoproteins; Glycoside Hydrolases; Hydrogen-Ion Concentration; Lectins; Methylation; Molecular Weight; Oligosaccharides; Periodic Acid; Plant Proteins; Pronase; Protein Binding; Serine; Sex; Species Specificity; Sulfur Radioisotopes; Threonine | 1974 |
In vitro and in vivo phosphorylation of myelin basic protein by cerebral protein kinase.
Topics: Adenosine Triphosphate; Animals; Autoradiography; Brain; Cattle; Cyclic AMP; Electrophoresis; Lipoproteins; Myelin Sheath; Nerve Tissue Proteins; Phosphorus Radioisotopes; Protein Kinases; Rats; Serine; Threonine | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Phosphatases in the substantia gelatinosa and motoneurones: a comparative histochemical study.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Animals; Cats; Cricetinae; Galactose; Glucosamine; Glucose-6-Phosphatase; Glycerophosphates; Guinea Pigs; Hexosephosphates; Histocytochemistry; Hydrogen-Ion Concentration; Mice; Motor Neurons; Nitrophenols; Pentosephosphates; Phosphates; Phosphoric Monoester Hydrolases; Rabbits; Ribose; Serine; Spinal Cord; Thiamine Pyrophosphate; Threonine | 1974 |
Identification of missense mutants by amino acid replacements in iso-1-cytochrome c from yeast.
Topics: Amino Acid Sequence; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Chymotrypsin; Cytochrome c Group; Electrophoresis; Genes; Heme; Hydrolysis; Isoleucine; Mutation; Peptides; Proline; RNA, Messenger; Saccharomyces cerevisiae; Serine; Threonine; Ultraviolet Rays | 1974 |
Biodegradative L-threonine deaminase of Salmonella typhimurium.
Topics: Aerobiosis; Anaerobiosis; Cross Reactions; Cyclic AMP; Enzyme Induction; Enzyme Repression; Glucose; Hydro-Lyases; Isoenzymes; Isoleucine; Mutation; Salmonella typhimurium; Serine; Stereoisomerism; Threonine; Transduction, Genetic | 1974 |
Amino acid transport and staphylococcal membrane vesicles.
Topics: Amino Acids; Amobarbital; Anaerobiosis; Arsenates; Carbon Radioisotopes; Cell Membrane; Chloromercuribenzoates; Cyanides; Depression, Chemical; Electron Transport; Ethylmaleimide; Glycerophosphates; Kinetics; Lactates; Lysostaphin; NAD; Nitrobenzenes; Oxalates; Protoplasts; Serine; Staphylococcus; Threonine | 1974 |
The isolation and partial characterization of a glycoprotein isolated from human gastric aspirates and from extracts of gastric mucosae.
Topics: ABO Blood-Group System; Amino Acids; Binding Sites; Borohydrides; Chromatography, Gas; Chromatography, Gel; Chromatography, Ion Exchange; Fucose; Galactosamine; Galactose; Gastric Juice; Gastric Mucosa; Glucosamine; Glycoproteins; Humans; Hydrogen-Ion Concentration; Hydrolysis; Oxidation-Reduction; Periodic Acid; Protein Binding; Protein Conformation; Serine; Threonine; Uronic Acids | 1974 |
Active transport of amino acids by membrane vesicles of Thiobacillus neapolitanus.
Topics: Amobarbital; Azides; Biological Transport, Active; Cell Membrane; Culture Media; Cyanides; Electron Transport; Glycine; Kinetics; Lactates; Leucine; NAD; Radioisotopes; Serine; Succinates; Thiobacillus; Thiosulfates; Threonine | 1974 |
Isolation of 32P-labeled phosphorylserine and phosphorylthreonine from Ehrlich mouse ascites tumor cells suspended in different isotonic media containing 32P-labeled adenosine triphosphate.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Cells, Cultured; Chromatography, Ion Exchange; Cyclic AMP; Mice; Organophosphorus Compounds; Phosphoproteins; Phosphorus Radioisotopes; Serine; Threonine | 1974 |
Studies of a homoserineless bradytroph of Neurospora crassa: demonstration of an altered aspartate beta-semialdehyde dehydrogenase.
Topics: Amino Acids; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Carbon Isotopes; Hydrogen-Ion Concentration; Isoleucine; Molecular Biology; Mutation; Neurospora; Serine; Temperature; Threonine | 1967 |
On collagens of invertebrates with special reference to Mytilus edulis.
Topics: Amino Acids; Annelida; Cestoda; Cnidaria; Collagen; Cystine; Drug Stability; Electrophoresis; Hexoses; Hydroxyproline; Invertebrates; Lysine; Mollusca; Protein Denaturation; Serine; Solubility; Temperature; Threonine | 1968 |
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. I. Inhibition by amino acids of the enzymes in threonine biosynthesis.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Brevibacterium; Cysteine; Glutathione; Isoleucine; Lyases; Lysine; Methionine; Phosphotransferases; Serine; Temperature; Threonine | 1968 |
Amino acid levels and enzyme activity in tissues of rats force-fed diets differing methionine content.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartate Aminotransferases; Cystine; Diet; Eating; Glutamates; Glycine; Hydro-Lyases; Liver; Male; Methionine; Muscles; Nitrogen; Organ Size; Ornithine; Rats; Serine; Statistics as Topic; Threonine; Transferases; Tryptophan Oxygenase; Tyrosine Transaminase | 1969 |
Studies of nuclear acidic proteins. Evidence for their phosphorylation, tissue specificity, selective binding to deoxyribonucleic acid, and stimulation effects on transcription.
Topics: Amino Acids; Animals; Cattle; Cell Nucleus; Centrifugation, Density Gradient; Chromosomes; DNA; DNA, Bacterial; Dogs; Electrophoresis; Female; Humans; Kidney; Liver; Male; Nucleoproteins; Organ Specificity; Phosphates; Phosphorus Isotopes; Placenta; Protein Binding; Protein Biosynthesis; Rats; RNA; RNA Nucleotidyltransferases; Serine; Species Specificity; Streptococcus pneumoniae; Threonine; Thymus Gland | 1971 |
Mutant strains of Escherichia coli K12 that use D-amino acids.
Topics: Amino Acids; Arginine; Chromosome Mapping; Coliphages; D-Amino-Acid Oxidase; Escherichia coli; Genetic Linkage; Genotype; Histidine; Isoleucine; Isomerism; Leucine; Lysine; Mutation; Phenylalanine; Proline; Serine; Threonine; Transduction, Genetic; Tryptophan; Tyrosine; Valine | 1971 |
Long-term adaptation of weanling rats to high dietary levels of methionine and serine.
Topics: Adaptation, Biological; Adrenal Cortex Hormones; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginase; Body Weight; Caseins; Depression, Chemical; Dietary Proteins; L-Serine Dehydratase; Liver; Male; Metabolic Clearance Rate; Methionine; Organ Size; Rats; Serine; Stimulation, Chemical; Taurine; Threonine; Time Factors; Tyrosine Transaminase | 1972 |
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases | 1971 |
Absorption of some amino acids by the haemoflagellate, Trypanosoma gambiense.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Carbon Isotopes; Cysteine; Glutamates; Glycine; Iodoacetates; Kinetics; Leucine; Lysine; Ornithine; Rats; Serine; Threonine; Trypanosoma brucei gambiense | 1972 |
Enzymic oxidation of some resistant D-amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Cattle; D-Amino-Acid Oxidase; Glutamates; Indicators and Reagents; Kidney; Liver; Lysine; Methionine; Methods; Oxidation-Reduction; Serine; Swine; Threonine; Time Factors | 1972 |
Structural studies of 4-acetamido-2-amino-2,4,6-trideoxy-D-glucose (N-acetylbacillosamine), the N-acetyldiamino sugar of Bacillus licheniformis.
Topics: Acetates; Acetylglucosamine; Amino Acids; Bacillus; Chemical Phenomena; Chemistry; Chromatography, Paper; D-Amino-Acid Oxidase; Hexosamines; Hydrogen-Ion Concentration; Hydrolysis; Magnetic Resonance Spectroscopy; Nitrobenzenes; Optical Rotation; Optical Rotatory Dispersion; Oxidation-Reduction; Periodic Acid; Polysaccharides, Bacterial; Potassium Permanganate; Serine; Stereoisomerism; Sugar Alcohols; Threonine | 1973 |
Lipolytic and hypoglycemic compounds obtained from cystoseira barbata J. Ag.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Blood Glucose; Chromatography, Gel; Chromatography, Paper; Eukaryota; Glutamine; Histidine; Leucine; Lipid Metabolism; Lysine; Methionine; Peptide Fragments; Rabbits; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Phosphorus-rich Aalpha polypeptide chains of pig and sheep fibrinogen.
Topics: Animals; Chromatography, Ion Exchange; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Molecular Weight; Peptide Fragments; Peptides; Phosphates; Serine; Sheep; Species Specificity; Spectrophotometry, Ultraviolet; Sulfites; Swine; Threonine; Trypsin | 1974 |
On the carbohydrate-protein linkage group in vitreous humor hyaluronate.
Topics: Amino Acids; Animals; Arabinose; Aspartic Acid; Borohydrides; Carbohydrates; Cattle; Chromatography, Gas; Chromatography, Gel; Chromatography, Paper; Fucose; Hexosamines; Hyaluronic Acid; Molecular Weight; Oxidation-Reduction; Proteins; Serine; Threonine; Viscosity; Vitreous Body | 1974 |
The phosphorylation of liver ribosomal proteins in vivo. Evidence that only a single small subunit protein (S6) is phosphorylated.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Carbon Radioisotopes; Deoxyribonucleases; Electrophoresis, Polyacrylamide Gel; Formaldehyde; Hepatectomy; Liver; Liver Regeneration; Male; Molecular Weight; Organophosphorus Compounds; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Polyribosomes; Protein Binding; Rats; Ribonucleases; Ribosomes; Serine; Spectrophotometry, Ultraviolet; Threonine; Trypsin | 1974 |
Plasma concentrations of tryptophan and other amino acids in manic-depressive patients.
Topics: Alanine; Arginine; Aspartic Acid; Bipolar Disorder; Emotions; Glutamates; Glycine; Humans; Isoleucine; Leucine; Methionine; Psychology; Serine; Threonine; Tryptophan; Tyrosine | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Analogues of human calcitonin. I. Influence of modifications in amino acid positions 29 and 31 on hypocalcaemic activity in the rat.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Calcitonin; Calcium; Dose-Response Relationship, Drug; Female; Hypocalcemia; Photometry; Rats; Regression Analysis; Serine; Structure-Activity Relationship; Threonine; Time Factors; Valine | 1974 |
Kinetic studies on the alkali-catalyzed hydrolysis and epimerization of model alkyl and hydroxyalkyl di- and tripeptides.
Topics: Alanine; Alcohols; Alkanes; Borates; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Leucine; Oligopeptides; Optical Rotation; Phosphates; Serine; Stereoisomerism; Threonine | 1974 |
[Free amino acids in the 24 h urine of healthy children (author's transl)].
Topics: Adolescent; Age Factors; Alanine; Amino Acids; Aminobutyrates; Carnosine; Child; Chromatography, Ion Exchange; Citrulline; Female; Glycine; Histidine; Humans; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Serine; Sex Factors; Threonine; Tyrosine; Valine | 1974 |
L-dihydroxyphenylalanine: effect on levels of free amino acids in rat liver.
Topics: Amino Acids; Animals; Aspartic Acid; Dihydroxyphenylalanine; Glutamates; Isoleucine; Liver; Male; Methionine; Organ Size; Rats; Serine; Threonine; Tyrosine | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
The peptide moiety of blood-group-specific glycoproteins. Some amino-acid sequences in the regions carrying the carbohydrate chains.
Topics: ABO Blood-Group System; Amino Acid Sequence; Amino Acids; Autoanalysis; Binding Sites; Body Fluids; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Paper; Female; Galactosamine; Glycopeptides; Glycoproteins; Humans; Hydrolysis; Ovarian Cysts; Peptide Fragments; Pronase; Serine; Threonine | 1974 |
Characterization of human colonic mucoprotein antigen.
Topics: Amino Acids; Animals; Antigens; Carbohydrates; Carcinoembryonic Antigen; Colon; Fucose; Galactose; Glucosamine; Glutamates; Glycine; Humans; Immune Sera; Immunoelectrophoresis; Molecular Weight; Mucoproteins; Neuraminic Acids; Proline; Rabbits; Serine; Threonine | 1974 |
Prebiotic synthesis of hydrophobic and protein amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Ammonia; Aspartic Acid; Autoanalysis; Chromatography, Gas; Glutamates; Glycine; Isoleucine; Leucine; Mass Spectrometry; Methane; Nitrogen; Proline; Serine; Threonine; Valine; Water | 1972 |
Atypical pattern of utilization of amino acids for mitochondrial protein synthesis in HeLa cells.
Topics: Amino Acids; Arginine; Chloramphenicol; Cycloheximide; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Emetine; Endoplasmic Reticulum; Female; Glutamine; HeLa Cells; Humans; Leucine; Lysine; Methionine; Mitochondria; Neoplasm Proteins; Phenylalanine; Polyribosomes; Serine; Threonine; Tritium; Tryptophan | 1973 |
A kinase that transfers the gamma-phosphoryl group of GTP to proteins of eukaryotic 40S ribosomal subunits.
Topics: Adenosine Triphosphate; Animals; Autoradiography; Cytosol; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; In Vitro Techniques; Liver; Phosphorus Radioisotopes; Protein Binding; Protein Kinases; Proteins; Rats; Ribosomes; Serine; Threonine | 1974 |
Purification and properties of tryptophan-synthase-inactivating enzymes from yeast.
Topics: Alcohol Oxidoreductases; Apoproteins; Aspartate Aminotransferases; Cell Fractionation; Chromatography, Ion Exchange; Glucosephosphate Dehydrogenase; Hexokinase; Hot Temperature; Hydro-Lyases; Kinetics; Peptide Hydrolases; Protein Denaturation; Pyridoxal Phosphate; Saccharomyces; Saccharomyces cerevisiae; Serine; Threonine; Tryptophan Synthase | 1972 |
Location of trpR mutations in the serB-thr region of Salmonella typhimurium.
Topics: Alleles; Chromosome Mapping; Chromosomes, Bacterial; Crosses, Genetic; Culture Media; Drug Resistance, Microbial; Genes, Regulator; Genetic Linkage; Genetics, Microbial; Genotype; Mutation; Operon; Phenotype; Recombination, Genetic; Salmonella typhimurium; Serine; Threonine; Transduction, Genetic; Tryptophan | 1972 |
Amino acid sequences in the -chains of adult bovine hemoglobins C-Rhodesia and D-Zambia.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Chromatography, Ion Exchange; Chymotrypsin; Cyanogen Bromide; Electrophoresis, Starch Gel; Globins; Glutamine; Glycine; Hemoglobins, Abnormal; Lysine; Pepsin A; Peptides; Serine; Species Specificity; Thermolysin; Thiocyanates; Threonine; Trypsin; Ultracentrifugation; Zambia; Zimbabwe | 1972 |
The presence of N-(purin-6-ylcarbamoyl)threonine in transfer ribonucleic acid species whose codons begin with adenine.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Arginine; Asparagine; Benzoates; Carbamates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Electrophoresis, Paper; Escherichia coli; Genetic Code; Glycolates; Isoleucine; Leucine; Lysine; Methionine; Purine Nucleotides; RNA, Bacterial; RNA, Transfer; Serine; Succinimides; Threonine; Tritium | 1972 |
Chemotaxis toward amino acids in Escherichia coli.
Topics: Amino Acids; Aspartic Acid; Bacteriological Techniques; Chemotaxis; Culture Media; Escherichia coli; Genetics, Microbial; Mutation; Oxygen Consumption; Proline; Serine; Threonine | 1972 |
Spectral and regulatory properties of biodegradative threonine deaminase.
Topics: Acetates; Acids; Acrylates; Adenosine Monophosphate; Aminobutyrates; Butyrates; Escherichia coli; Fumarates; Hydro-Lyases; Hydroxybutyrates; Kinetics; Propionates; Serine; Spectrophotometry; Threonine | 1972 |
Transfer ribonucleic acids from mouse plasmacytoma tumors producing kappa and immunoglobulin chains.
Topics: Amino Acyl-tRNA Synthetases; Animals; Carbon Isotopes; Cell-Free System; Chromatography; Chromatography, Ion Exchange; Escherichia coli; Glutamates; Immunoglobulin Fragments; Leucine; Methionine; Mice; Microsomes; Plasmacytoma; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; Serine; Threonine; Transfer RNA Aminoacylation; Tritium; Trypsin | 1973 |
Transport systems for alanine, serine, and glycine in Escherichia coli K-12.
Topics: Alanine; Autoradiography; Biological Transport, Active; Chromosome Mapping; Escherichia coli; Glycine; Leucine; Mutation; Serine; Stereoisomerism; Threonine; Transduction, Genetic | 1973 |
Multiplicity of leucine transport systems in Escherichia coli K-12.
Topics: Alanine; Bacterial Proteins; Biological Transport, Active; Chromatography, DEAE-Cellulose; Escherichia coli; Isoleucine; Leucine; Mutation; Nitrosoguanidines; Osmosis; Protein Binding; Serine; Stereoisomerism; Threonine; Transduction, Genetic; Valine | 1973 |
Detection of inosine-containing transfer ribonucleic acid species by affinity chromatography on columns of anti-inosine antibodies.
Topics: Alkylation; Animals; Antibodies; Arginine; Carbon Radioisotopes; Chromatography, Affinity; Cyanides; Escherichia coli; Evaluation Studies as Topic; Guanosine; Inosine; Isoleucine; Methionine; Methods; Proline; Rabbits; RNA, Bacterial; RNA, Transfer; Serine; Structure-Activity Relationship; Threonine; Transfer RNA Aminoacylation; Tritium; Valine | 1973 |
Regulation of biodegradative threonine deaminase. 3. Effects of beta substituents of substrate on absorption spectrum and circular dichroism of the enzyme-bound pyridoxal phosphate.
Topics: Alanine; Binding Sites; Chlorine; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Circular Dichroism; Escherichia coli; Hydro-Lyases; Hydroxylation; Kinetics; Molecular Conformation; Protein Binding; Pyridoxal Phosphate; Schiff Bases; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Threonine; Time Factors; Valine | 1974 |
[Purification and partial characterization of two malate synthases of Echerichia coli].
Topics: Acetates; Ammonium Sulfate; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Electrophoresis; Enzyme Activation; Escherichia coli; Fluorine; Glycolates; Hot Temperature; Isoenzymes; Malates; Molecular Weight; Nitrobenzenes; Oxalates; Oxo-Acid-Lyases; Serine; Threonine; Ultracentrifugation | 1973 |
Transport of biosynthetic intermediates: homoserine and threonine uptake in Escherichia coli.
Topics: Amino Acids; Bacterial Proteins; Biological Transport, Active; Carbon Radioisotopes; Culture Media; Escherichia coli; Homoserine; Leucine; Mutagens; Mutation; Nitrosoguanidines; Serine; Threonine; Time Factors | 1974 |
Studies on L-serine deaminase in Escherichia coli K-12.
Topics: Amino Acids; Cell-Free System; Deamination; Drug Stability; Escherichia coli; Hydro-Lyases; Hydrogen-Ion Concentration; L-Serine Dehydratase; Mutation; Nitrogen; Proline; Pyruvates; Serine; Stereoisomerism; Succinates; Threonine; Toluene | 1974 |
Structure of the mannan from Saccharomyces strain FH4C, a mutant constitutive for invertase biosynthesis. II. Protein moiety and components of the carbohydrate-peptide bonds.
Topics: Amino Acids; Arthrobacter; Binding Sites; Chromatography, Gel; Chromatography, Paper; Fungal Proteins; Glucosamine; Glycoproteins; Glycoside Hydrolases; Glycosides; Hydrogen-Ion Concentration; Kinetics; Mannose; Mutation; Polysaccharides; Protein Binding; Saccharomyces; Saccharomyces cerevisiae; Serine; Species Specificity; Spectrophotometry, Ultraviolet; Sucrase; Threonine | 1974 |
The role of dolicholmonophosphate in glycoprotein biosynthesis in Saccharomyces cerevisiae.
Topics: Borohydrides; Carbon Radioisotopes; Chromatography, Paper; Dialysis; Diterpenes; Fungal Proteins; Glycoproteins; Guanine Nucleotides; Magnesium; Manganese; Mannose; Oligosaccharides; Phospholipids; Saccharomyces cerevisiae; Serine; Subcellular Fractions; Threonine; Time Factors | 1974 |
Formation of biodegradative threonine deaminase in Escherichia coli.
Topics: Amino Acids; Chloramphenicol; Culture Media; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Repression; Escherichia coli; Glucose; Hydro-Lyases; Saccharomyces cerevisiae; Serine; Stereoisomerism; Structure-Activity Relationship; Threonine | 1974 |
Persisting circadian oscillations in enzyme activity in non-dividing cultures of Euglena.
Topics: Acid Phosphatase; Alanine; Alkaline Phosphatase; Amino Acid Oxidoreductases; Aminohydrolases; Cell Division; Circadian Rhythm; Darkness; Euglena gracilis; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Kinetics; L-Lactate Dehydrogenase; Light; Serine; Threonine | 1972 |
Experimental protein-energy deficiency in rats. Ratio of serine+glycine to threonine as an index of deficiency.
Topics: Amino Acids; Animals; Blood Proteins; Body Weight; Chromatography; Diarrhea; Dietary Proteins; Edema; Feeding Behavior; Female; Glycine; Hair; Male; Protein Deficiency; Protein-Energy Malnutrition; Rats; Serine; Threonine | 1973 |
Cerebral amino acid uptake in vivo in newborn mice.
Topics: Age Factors; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Blood-Brain Barrier; Brain; Cell Membrane Permeability; Dose-Response Relationship, Drug; Glycine; Histidine; Isoleucine; Methionine; Mice; Serine; Threonine; Tryptophan; Valine | 1972 |
Amino acid metabolism in chameleon liver.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Female; Glutamates; Glutamine; Glycine; Histidine; Keto Acids; Liver; Lizards; Lysine; Male; Methionine; Ornithine; Phenylalanine; Pyruvates; Serine; Threonine; Tryptophan | 1972 |
Sequence of limiting amino acids in gelatin for the growing chick.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Chickens; Female; Gelatin; Glycine; Histidine; Isoleucine; Lysine; Male; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Valine | 1972 |
Genetic analysis of free plasma amino acids in pure strains of mature chickens.
Topics: Amino Acids; Animals; Autoanalysis; Breeding; Chickens; Female; Genotype; Isoleucine; Male; Molecular Biology; Phenotype; Proline; Serine; Statistics as Topic; Threonine; Valine | 1972 |
Amino acid compositions of all the tryptic peptides from the and polypeptide chains of adult hemoglobin of the slow loris (Nycticebus coucang). Biochemical studies on hemoglobins and myoglobins. X.
Topics: Alanine; Amino Acids; Animals; Arginine; Chromatography; Chromatography, Paper; Glutamine; Hemoglobins; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myoglobin; Peptides; Phenylalanine; Primates; Serine; Threonine; Trypsin; Tyrosine; Valine | 1972 |
Characterization of chlorosis-inducing toxins from a plant pathogenic Pseudomonas Sp.
Topics: Adipates; Amino Acids; Biological Assay; Chromatography, Gas; Chromatography, Thin Layer; Dipeptides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pigmentation; Poaceae; Protein Conformation; Pseudomonas; Serine; Spectrophotometry, Infrared; Threonine; Toxins, Biological | 1972 |
[Correlations of plasma amino acids in the rat during hypercapnia].
Topics: Amino Acids; Analysis of Variance; Animals; Chromatography, Ion Exchange; Glycine; Hypercapnia; Male; Rats; Serine; Threonine | 1972 |
Studies on protamines. XVI. The complete amino acid sequence of clupeine YII.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Chromatography; Fishes; Male; Proline; Protamines; Serine; Spermatozoa; Threonine; Valine | 1972 |
Studies on protamines. XVII. The complete amino acid sequence of clupeine YI.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Cell Nucleus; Chromatography; Fishes; Glycine; Isoleucine; Male; Proline; Protamines; Serine; Spermatozoa; Threonine | 1972 |
[Demonstration of tumor-induced amino acid changes in the extracellular fluid using two-way separation by high voltage electrophoresis followed by chromatography].
Topics: Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Chromatography; Cystine; Electrophoresis; Extracellular Space; Glutamates; Glutamine; Rats; Sarcoma, Yoshida; Serine; Threonine | 1972 |
Interaction of 4-nitroquinoline 1-oxide and related carcinogens with histone and aliphatic amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinogens; Cattle; Chemical Phenomena; Chemistry; Glutamates; Glycine; Histones; Isoleucine; Leucine; Lysine; Methionine; Proline; Protein Denaturation; Quinolines; Serine; Spectrophotometry; Threonine; Thymus Gland; Valine | 1972 |
Amino acid sequence of the threonine-containing mureins of coryneform bacteria.
Topics: Amino Acid Sequence; Amino Acids; Arthrobacter; Autoanalysis; Bacteria; Brevibacterium; Cell Wall; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Corynebacterium; Erysipelothrix; Glucosamine; Glutamates; Hydrolysis; Lysine; Muramic Acids; Peptides; Peptidoglycan; Serine; Species Specificity; Stereoisomerism; Threonine | 1973 |
Rat liver aminomalonate decarboxylase. Identity with cytoplasmic serine hydroxymethylase and allothreonine aldolase.
Topics: Alanine; Aldehyde-Lyases; Amino Acids; Animals; Binding Sites; Binding, Competitive; Carbon Isotopes; Carboxy-Lyases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Glycine; Liver; Male; Malonates; Mitochondria, Liver; Molecular Weight; Protein Denaturation; Rats; Serine; Tetrahydrofolates; Threonine; Transferases; Tritium | 1973 |
A growth factor for animal cells derived from peptone. I. Isolation and characterization of the growth factor.
Topics: Alanine; Aspartic Acid; Chromatography, Gel; Chromatography, Paper; Clone Cells; Culture Media; Culture Techniques; Glutamates; Glycine; Growth Substances; L Cells; Lysine; Molecular Weight; Peptones; Serine; Spectrophotometry; Threonine | 1973 |
Preparation and reactions of nitrate esters of N-acylserine and -threonine derivatives.
Topics: Acylation; Nitrates; Serine; Threonine | 1973 |
Serine transhydroxymethylase. A kinetic study of the synthesis of serine in the absence of tetrahydrofolate.
Topics: Acetaldehyde; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Feedback; Folic Acid; Formaldehyde; Glycine; Hydrogen; Kinetics; Models, Chemical; Protons; Schiff Bases; Serine; Structure-Activity Relationship; Tetrahydrofolates; Threonine; Transferases; Tritium | 1973 |
Hyperglutamatemia in primary gout.
Topics: Adult; Aged; Alanine; Ammonia; Chromatography; Fasting; Glutamates; Glutamine; Glycine; Gout; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Serine; Threonine; Uric Acid | 1973 |
A comparative study of the major glycoprotein isolated from normal and neoplastic gastric mucosa.
Topics: Agglutination Tests; Amino Acids; Blood Group Antigens; Chromatography; Chromatography, Gel; Fucose; Galactosamine; Galactose; Gastric Mucosa; Glucosamine; Glycoproteins; Humans; Peptic Ulcer; Serine; Stomach Neoplasms; Threonine | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
Phosphoprotein component of vaccinia virions.
Topics: Autoradiography; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Oxidative Phosphorylation; Phosphopeptides; Phosphoproteins; Phosphorus Isotopes; Serine; Threonine; Tritium; Trypsin; Vaccinia virus; Viral Proteins | 1973 |
The effect of L-3,4-dihydroxyphenylalanine administration on glucose metabolism in brain.
Topics: Administration, Oral; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Brain; Carbon Isotopes; Depression, Chemical; Dihydroxyphenylalanine; Glucose; Glutamine; Glycine; Injections, Intraperitoneal; Kinetics; Lactates; Male; Rats; Serine; Stimulation, Chemical; Taurine; Threonine; Time Factors | 1973 |
Developmental transitions in uptake of amino acids by synaptosomal fractions isolated from rat cerebral cortex.
Topics: Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Biological Transport; Carbon Isotopes; Cerebral Cortex; Kinetics; Proline; Rats; Serine; Sodium; Stimulation, Chemical; Synaptosomes; Threonine; Valine | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Properties of the major glycoprotein of the beef erythrocyte membrane.
Topics: Amino Acids; Animals; Blood Proteins; Carbohydrates; Cattle; Cell Membrane; Chromatography, Gel; Densitometry; Electrophoresis; Erythrocytes; Glycoproteins; Hexosamines; Hexoses; Molecular Weight; Neuraminic Acids; Serine; Threonine; Ultracentrifugation | 1973 |
Calf brain phosvitin kinase. II. Purification and characterization of three different fractions of phosvitin kinase.
Topics: Adenosine Triphosphate; Animals; Brain; Cattle; Chromatography, Ion Exchange; Egg Proteins; Electrophoresis, Polyacrylamide Gel; Phosphoproteins; Phosphorus Isotopes; Phosphotransferases; Serine; Threonine | 1973 |
Alterations in renal and plasma amino acid concentrations during renal compensatory growth.
Topics: Alanine; Amino Acids; Animals; Kidney; Kidney Cortex; Leucine; Male; Methionine; Nephrectomy; Ornithine; Rats; Serine; Starvation; Threonine; Tyrosine | 1973 |
Carbon 13 nuclear magnetic resonance of pentapeptides of glycine containing central residues of serine, threonine, aspartic and glutamic acids, asparagine, and glutamine.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Computers; Fourier Analysis; Glutamates; Glutamine; Glycine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mathematics; Oligopeptides; Protons; Serine; Threonine; Time Factors | 1973 |
Composition of a specific intercellular agglutination factor.
Topics: Agglutination Tests; Amino Acids; Ascomycota; Carbohydrates; Chromatography, Gel; Glycoproteins; Glycoside Hydrolases; Haploidy; Hydrogen-Ion Concentration; Lectins; Mannose; Phosphates; Plant Proteins; Polysaccharides; Pronase; Serine; Subtilisins; Sulfur Radioisotopes; Threonine | 1973 |
Interactions between copper (II) ions and L-threonine, L-allo-threonine and L-serine in aqueous solution.
Topics: Binding Sites; Circular Dichroism; Copper; Deuterium; Hydrogen-Ion Concentration; Isomerism; Ligands; Mathematics; Molecular Conformation; Optical Rotation; Protein Binding; Serine; Spectrophotometry; Threonine | 1973 |
The presence of phosphoserine and phosphothreonine in tryptic digest degradation products of pig fibrinogen.
Topics: Animals; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Fibrinogen; Organophosphorus Compounds; Serine; Swine; Threonine; Trypsin | 1973 |
Evolution of glycoproteins as judged by the frequency of occurrence of the tripeptides Asn-X-Ser and Asn-X-Thr in proteins.
Topics: Amino Acid Sequence; Animals; Asparagine; Biological Evolution; Glycoproteins; Oligopeptides; Peptide Fragments; Serine; Threonine | 1973 |
Purification and characterization of a B6-independent threonine dehydratase from Pseudomonas putida.
Topics: Amino Acids; Ammonium Sulfate; Binding Sites; Carbon Radioisotopes; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gas; Chromatography, Gel; Culture Media; Electrophoresis, Polyacrylamide Gel; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Protamines; Pseudomonas; Pyridoxal Phosphate; Serine; Threonine; Tritium; Ultracentrifugation | 1974 |
Brain phosphoproteins: the effect of short experiences on the phosphorylation of nuclear proteins of rat brain.
Topics: Adenosine Monophosphate; Animals; Avoidance Learning; Brain; Cell Nucleus; Conditioning, Psychological; Electrophoresis, Disc; Electroshock; Histones; Nerve Tissue Proteins; Oxidative Phosphorylation; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Rats; RNA; Serine; Threonine; Tritium | 1974 |
Synthesis and catalytic properties of the heptapeptide L-seryl-L-prolyl-L-cysteinyl-L-steryl-alpha-L-glutamyl-L-threonyl-L-tyrosine.
Topics: Acetates; Carboxypeptidases; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Dicyclohexylcarbodiimide; Esters; Glutamates; Hydrogen-Ion Concentration; Kinetics; Mathematics; Nitrophenols; Oligopeptides; Optical Rotation; Proline; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Threonine; Tyrosine | 1974 |
The 5-O-beta-D-galactofuranosyl-containing exocellular glycopeptide of Penicillium charlesii. Occurrence of ethanolamine and partial characterization of the peptide portion and the carbohydrate-peptide linkage.
Topics: Amino Acids; Aminobutyrates; Borohydrides; Chemical Phenomena; Chemistry; Ethanolamines; Furans; Galactose; Glycopeptides; Hydrogen-Ion Concentration; Mannitol; Mannose; Monosaccharides; Oligosaccharides; Palladium; Penicillium; Peptides; Polysaccharides; Serine; Spectrophotometry, Ultraviolet; Sugar Phosphates; Threonine; Tritium | 1974 |
Localization of the histidine-rich protein in keratohyalin: a morphologic and macromolecular marker in epidermal differentiation.
Topics: Alanine; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cell Differentiation; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Glutamates; Glycine; Histidine; Histocytochemistry; Keratins; Macromolecular Substances; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Serine; Skin; Threonine; Tritium | 1974 |
An acetylated N-terminus of adenovirus type 2 hexon protein.
Topics: Acetylation; Adenoviridae; Alanine; Amino Acid Sequence; Carbon Radioisotopes; Chromatography, Ion Exchange; Electrophoresis, Paper; Hydrogen-Ion Concentration; Mass Spectrometry; Peptide Fragments; Proline; Serine; Threonine; Time Factors; Viral Proteins | 1974 |
Selective malabsorption of vitamin B 12: report of a case with metabolic studies.
Topics: Alanine; Amino Acids; Anemia, Macrocytic; Child; Chromatography, Gas; Glycine; Hemoglobins; Histidine; Humans; Isoleucine; Leucine; Malabsorption Syndromes; Male; Malonates; Methionine; Proteinuria; Renal Tubular Transport, Inborn Errors; Reticulocytes; Serine; Taurine; Threonine; Tyrosine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Analysis of methylthiohydantoins of amino acids by gas-liquid chromatography of their trimethylsilyl derivatives.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Chromatography, Gas; Evaluation Studies as Topic; Hydantoins; Hydroxylysine; Hydroxyproline; Methods; Peptides; Proteins; Serine; Silicon; Thiohydantoins; Threonine; Time Factors | 1974 |
Hyperglutamatemia in primary gout.
Topics: Administration, Oral; Alanine; Erythrocytes; Glutamates; Glutamine; Glycine; Gout; Humans; Male; Puberty; Serine; Threonine; Time Factors; Uric Acid | 1974 |
Phosphorylation of selected serine and threonine residues in myelin basic protein by endogenous and exogenous protein kinases.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Autoradiography; Cattle; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Lipoproteins; Myelin Sheath; Nerve Tissue Proteins; Peptides; Phosphorus Radioisotopes; Protein Kinases; Rabbits; Serine; Threonine; Trypsin | 1974 |
Phosphorylation of ribosomal proteins: preparation of rat liver ribosomal protein kinases. Assay of the phosphorylation of ribosomal subunit proteins. Assay of the function of phosphorylated ribosomes.
Topics: Animals; Autoradiography; Chromatography, DEAE-Cellulose; Cytosol; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Evaluation Studies as Topic; Liver; Methods; Organophosphorus Compounds; Phosphoproteins; Phosphorus Radioisotopes; Protein Kinases; Proteins; Rats; Ribosomes; Serine; Spectrophotometry, Ultraviolet; Threonine | 1974 |
Synthesis of some glycodipeptides containing hydroxyamino acids, and their stabilities to acids and bases.
Topics: Acetylation; Amides; Borohydrides; Chemical Phenomena; Chemistry; Chromatography; Esters; Glycopeptides; Hydrogen-Ion Concentration; Hydrolysis; Methods; Optical Rotation; Serine; Spectrophotometry, Ultraviolet; Threonine | 1974 |
Altered amino acid concentrations accompanying suppression of malignancy of mouse melanoma cells by 5-bromodeoxyuridine.
Topics: Alanine; Amino Acids; Animals; Asparagine; Bromodeoxyuridine; Cells, Cultured; Glutamates; Glutamine; Glycine; Lysine; Melanoma; Methionine; Mice; Neoplasm Proteins; Ornithine; Phenylalanine; Pigmentation; Proline; Serine; Threonine; Valine | 1974 |
Plasma and rumen fluid components of steers fed two sources and levels of nitrogen.
Topics: Administration, Oral; Amino Acids; Amino Acids, Essential; Ammonia; Animal Feed; Animals; Arginine; Blood Urea Nitrogen; Body Weight; Cattle; Fatty Acids, Volatile; Glutamates; Glycine; Glycine max; Lysine; Male; Nitrogen; Propionates; Rumen; Serine; Threonine; Urea; Zea mays | 1974 |
Neutral sugars from the hyaluronate-peptide of vitreous humor.
Topics: Amino Acids; Animals; Arabinose; Cattle; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Fucose; Galactosamine; Glucosamine; Glucuronates; Heptoses; Hyaluronic Acid; Macromolecular Substances; Peptides; Serine; Threonine; Vitreous Body | 1974 |
A simple method for large-scale preparation of chick embryo tRNA.
Topics: Alanine; Animals; Asparagine; Carbon Radioisotopes; Chick Embryo; Chromatography, DEAE-Cellulose; Chromatography, Gel; Evaluation Studies as Topic; Glycine; Hydrogen-Ion Concentration; Methods; RNA, Transfer; Serine; Threonine; Time Factors; Valine | 1974 |
Regulation of homoserine biosynthesis by L-cysteine, a terminal metabolite of a linked pathway.
Topics: Alcohol Oxidoreductases; Amino Acids; Cysteine; Escherichia coli; Feedback; Rhodopseudomonas; Rhodospirillum; Serine; Threonine | 1967 |
[Metabolic products of microorganisms. 5l. On the mechanism of action of borrelidin-inhibition of the threonine incorporation in sRNA].
Topics: Anti-Bacterial Agents; Bacteriological Techniques; Carbon Isotopes; Escherichia coli; Leucine; RNA, Transfer; Serine; Streptomyces; Threonine; Valine | 1966 |
Glycine uptake in Escherichia coli. II. Glycine uptake, exchange, and metabolism by an isolated membrane preparation.
Topics: Alanine; Arsenic; Autoradiography; Azides; Biological Transport; Carbon Isotopes; Cell Membrane; Chromatography, Thin Layer; Cold Temperature; Cyanides; Dinitrophenols; Escherichia coli; Glucose; Glycine; Helium; Hydrazines; Hydrogen-Ion Concentration; Hydroxylamines; Iodoacetates; Magnesium; Mercury; Nucleotides; Phosphatidylethanolamines; Serine; Sulfonic Acids; Threonine | 1968 |
Chromatographic studies of pyrimidine metabolism. I. The metabolic products of aspartate-14C in Escherichia coli.
Topics: Aspartic Acid; Carbon Isotopes; Chromatography, Paper; Escherichia coli; Methods; Pyrimidines; Serine; Threonine | 1968 |
The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K 12. 4. Isolation, molecular weight, amino acid analysis and behaviour of the sulfhydryl groups of the protein catalyzing the two activities.
Topics: Alcohol Oxidoreductases; Amino Acids; Aspartic Acid; Autoanalysis; Benzoates; Binding Sites; Buffers; Chemical Phenomena; Chemistry; Chromatography, Gel; Electrophoresis, Disc; Escherichia coli; Kinetics; Molecular Weight; Nitrobenzenes; Phosphotransferases; Serine; Spectrophotometry; Sulfhydryl Compounds; Threonine; Ultracentrifugation | 1968 |
Fluorescence studies of substrate and subunit interactions of the beta-2 protein of Escherichia coli tryptophan synthetase.
Topics: Bacterial Proteins; Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Fluorescence; Fluorometry; Hydrogen-Ion Concentration; Indoles; Ligases; Pyridoxal Phosphate; Serine; Spectrophotometry; Threonine; Tryptophan | 1968 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
Evidence for a methionine-controlled homoserine dehydrogenase in Salmonella typhimurium.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Amino Acids; Aspartic Acid; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Hot Temperature; Methionine; Molecular Weight; Mutation; Salmonella typhimurium; Serine; Threonine | 1969 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
O-alkylhomoserine and methionine biosynthesis in Corynebacterium.
Topics: Amino Acids; Corynebacterium; Culture Media; Cysteine; Escherichia coli; Homocysteine; Methionine; Serine; Threonine | 1969 |
Unavailability of cystine from trypsin inhibitors as a factor contributing to the poor nutritive value of navy beans.
Topics: Amino Acids; Animals; Aspartic Acid; Chickens; Chymotrypsin; Cystine; Diet; Feces; Glutamates; Hot Temperature; Intestinal Mucosa; Nutritional Physiological Phenomena; Organ Size; Pancreas; Pepsin A; Plant Proteins; Plants, Edible; Proline; Protein Binding; Serine; Threonine; Trypsin; Trypsin Inhibitors | 1969 |
Identification of the sites of binding of acetyl and malonyl groups to the pigeon liver fatty acid synthetase complex.
Topics: Acetates; Amides; Amino Acids; Animals; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Columbidae; Electrophoresis; Formates; Hydroxylamines; Ligases; Liver; Malonates; Pantothenic Acid; Pepsin A; Serine; Threonine | 1970 |
Protein-bound phosphorylthreonine in some tissues and organisms.
Topics: Animals; Cell Nucleus; Chromatography, Ion Exchange; Erythrocytes; Escherichia coli; Humans; Liver; Muscles; Phosphates; Phosphoric Acids; Phosphorus Isotopes; Protein Binding; Rats; Saccharomyces; Serine; Threonine | 1970 |
Structure of serine tRNA from Escherichia coli. I. Purification of serine tRNA's with different codon responses.
Topics: Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Escherichia coli; Genetic Code; Ligases; Liver; Nucleotides; Rats; Ribonucleases; RNA, Bacterial; RNA, Transfer; Saccharomyces; Serine; Spectrum Analysis; Threonine; Ultraviolet Rays | 1971 |
The effect of branched chain amino acids on the synthesis of isoleucine from threonine and pyruvate in crude extracts from Escherichia coli.
Topics: Alanine; Aspartic Acid; Chromatography, Thin Layer; Escherichia coli; Isoleucine; Leucine; Pyruvates; Serine; Threonine; Tissue Extracts; Valine | 1970 |
Biochemical bases for the antimetabolite action of L-serine hydroxamate.
Topics: Bacterial Proteins; Carbon Isotopes; Culture Media; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Glycerolphosphate Dehydrogenase; Glycine; Hydroxamic Acids; Leucine; Ligases; Mutagens; Mutation; Nitrosoguanidines; RNA, Bacterial; Serine; Spectrophotometry; Stereoisomerism; Threonine; Tritium; Ultracentrifugation; Uracil | 1971 |
Biosynthetic L-threonine deaminase as the origin of L-serine sensitivity of Escherichia coli.
Topics: Butyrates; Culture Media; Escherichia coli; Hydro-Lyases; Isoleucine; Keto Acids; Serine; Threonine | 1971 |
RNA codons and protein synthesis. 15. Dissimilar responses of mammalian and bacterial transfer RNA fractions to messenger RNA codons.
Topics: Acylation; Amino Acid Sequence; Animals; Arginine; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Genetic Code; Genetics, Microbial; Guinea Pigs; Isoleucine; Liver; Lysine; Methionine; Molecular Biology; Protein Binding; Protein Biosynthesis; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine; Tritium | 1968 |
Serine metabolism in the culture form of Trypanosoma cruzi: synthesis of other amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Glutamates; Glycine; Protein Biosynthesis; Proteins; Serine; Threonine; Trypanosoma cruzi | 1971 |
Rapid electrophoretic analysis for histone phosphorylation. A reinvestigation of phosphorylation of lysine-rich histone during rat liver regeneration.
Topics: Alkaline Phosphatase; Animals; Chromatography, Ion Exchange; Densitometry; Electrophoresis; Escherichia coli; Hepatectomy; Histones; Kidney; Leucyl Aminopeptidase; Liver; Liver Regeneration; Methods; Phosphates; Phosphorus Isotopes; Pronase; Rats; Serine; Swine; Threonine; Time Factors; Urea | 1971 |
Amino-acid protection of ultra-violet-irradiated Bacillus subtilis.
Topics: Acid-Base Equilibrium; Alanine; Bacillus subtilis; Culture Media; Glycine; Histidine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
The protein-polysaccharide linkages in complexes from cartilage and cornea.
Topics: Animals; Aspartic Acid; Binding Sites; Cartilage; Cattle; Cornea; Mucopolysaccharidosis IV; Polysaccharides; Proteins; Rabbits; Serine; Threonine; Uracil Nucleotides; Xylose | 1967 |
Studies on the specificity of Bacillus subtilis neutral protease with synthetic substrates.
Topics: Alanine; Amino Acid Sequence; Bacillus subtilis; Catalysis; Histidine; Isoleucine; Kinetics; Leucine; Peptide Hydrolases; Peptides; Phenylalanine; Serine; Threonine; Valine | 1967 |
[Studies on the glycoproteins. Action of alkalies on the O-seryl- and O-threonyl-beta-N-acetyl-D-glucosaminides. Mechanism of the "beta-elimination"].
Topics: Alkalies; Glucosamine; Glycoproteins; Serine; Threonine | 1967 |
The NH2-terminal residues of Bacillus subtilis proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus subtilis; Carbon Isotopes; Chromatography, Gel; Escherichia coli; Fluorine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Nitrobenzenes; Proteins; Ribosomes; Serine; Species Specificity; Threonine; Tritium; Valine | 1968 |
On the C-terminal amino acid of bacterial alpha-amylase.
Topics: Alanine; Amino Acid Sequence; Amylases; Aspartic Acid; Bacillus subtilis; Carbon; Chemical Phenomena; Chemistry; Electrophoresis; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Paper; Serine; Threonine; Tyrosine; Valine | 1968 |
Serine-containing active center of alkaline proteinase of Aspergillus flavus.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arthrobacter; Aspergillus; Bacillus subtilis; Binding Sites; Chromatography, Ion Exchange; Chromatography, Paper; Glycine; Isoflurophate; Methionine; Peptide Hydrolases; Phosphorus Isotopes; Serine; Streptomyces; Threonine; Trypsin | 1969 |
Structure and properties of hemocyanins. IV. Dissociation of Helix pomatia hemocyanin by succinylation into functional subunits.
Topics: Anhydrides; Animals; Carbohydrates; Chemical Phenomena; Chemistry; Chromatography, Gel; Copper; Dextrans; Edetic Acid; Hemocyanins; Microscopy, Electron; Molecular Weight; Osmolar Concentration; Oxygen; Protein Binding; Serine; Snails; Spectrum Analysis; Succinates; Threonine; Tyrosine; Ultracentrifugation; Viscosity | 1969 |
The amino-terminal residues of Bacillus subtilis proteins made in vitro.
Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Chromatography, Gel; Folic Acid; Formates; Kinetics; Methionine; Molecular Weight; Peptide Biosynthesis; Peptide Hydrolases; RNA, Messenger; Serine; Threonine; Tritium; Valine | 1970 |
Transfer RNA patterns in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Chromatography; Female; Histidine; Leucine; Liver Diseases; Lysine; Methionine; Methylation; p-Dimethylaminoazobenzene; Phenylalanine; Precancerous Conditions; Rats; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
Phosphorylation of ribosomal proteins in rabbit reticulocytes. Characterization and regulatory aspects.
Topics: Alkaline Phosphatase; Animals; Autoradiography; Centrifugation, Density Gradient; Cycloheximide; Detergents; Edetic Acid; Electrophoresis; Endopeptidases; Escherichia coli; Fluorides; In Vitro Techniques; Kinetics; Liver; Molecular Weight; Muscles; Myocardium; Osmolar Concentration; Phosphates; Phospholipids; Phosphorus Isotopes; Protein Biosynthesis; Proteins; Rabbits; Reticulocytes; Ribosomes; RNA; Serine; Solubility; Sulfuric Acids; Threonine | 1970 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
[Glycopeptides of immunoglobulins, Microheterogeneity of the oligosaccharide chains of an immunoglobulin M from Waldenstrom's disease].
Topics: Amino Acid Sequence; Aspartic Acid; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Fucose; Galactose; Glucosamine; Glutamates; Histidine; Humans; Immunoglobulin M; Immunoglobulins; Lysine; Mannose; Neuraminic Acids; Oligosaccharides; Papain; Peptides; Proline; Serine; Threonine; Tyrosine; Valine; Waldenstrom Macroglobulinemia | 1970 |
Isolation of a macroglycopeptide from human platelets.
Topics: Blood Platelets; Cell Membrane; Chromatography, DEAE-Cellulose; Chromatography, Gel; Diffusion; Electrophoresis, Disc; Galactose; Glucosamine; Glycopeptides; Hexosamines; Humans; Immunodiffusion; Mathematics; Molecular Weight; Mucins; Neuraminic Acids; Papain; Peptide Hydrolases; Peptides; Platelet Adhesiveness; Polysaccharides; Proline; Serine; Threonine; Trypsin; Ultracentrifugation | 1970 |
Suppression by derepression in threonine dehydratase-deficient mutants of Bacillus subtilis.
Topics: Adenine Nucleotides; Bacillus subtilis; Carbon Isotopes; Cell-Free System; Chemical Precipitation; Chromatography, Paper; Chromosome Mapping; Culture Media; Enzyme Activation; Enzyme Repression; Ethanol; Genes; Genetics, Microbial; Glutathione; Hydro-Lyases; Isoleucine; Keto Acids; L-Serine Dehydratase; Mutation; Recombination, Genetic; Serine; Suppression, Genetic; Threonine; Transformation, Genetic; Ultracentrifugation | 1971 |
Minor threonine dehydratase encoded within the threonine synthetic region of Bacillus subtilis.
Topics: Bacillus subtilis; Chromosome Mapping; Colorimetry; Crosses, Genetic; Culture Media; DNA, Bacterial; Enzyme Activation; Genetics, Microbial; Hydro-Lyases; Indicators and Reagents; Isoleucine; Mutagens; Mutation; Nitrosoguanidines; Phosphotransferases; Serine; Stereoisomerism; Suppression, Genetic; Threonine; Transformation, Genetic | 1971 |
Solubilization and chemical and immunochemical characterization of sparingly soluble canine gastric mucin.
Topics: Alkylation; Amino Acids; Animals; Boron Compounds; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Dogs; Electrophoresis; Ethylmaleimide; Fucose; Galactose; Gastric Mucins; Gastric Mucosa; Glucosamine; Glycoproteins; Hexosamines; Immunodiffusion; Immunoelectrophoresis; Neuraminic Acids; Oxidation-Reduction; Phosphates; Proline; Rabbits; Serine; Sodium; Sodium Chloride; Sodium Hydroxide; Solubility; Sulfhydryl Reagents; Sulfites; Sulfur Isotopes; Threonine | 1971 |
Threonine deaminase (dehydratase) in Azotobacter chroococcum.
Topics: Adenosine Monophosphate; Ammonia; Arsenic; Aspartic Acid; Azotobacter; Butyrates; Chromatography; Cyanides; Edetic Acid; Enzyme Activation; Fluorides; Glutamates; Hydro-Lyases; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Potassium; Pyridoxal Phosphate; Quinolines; Serine; Sulfites; Thiocarbamates; Threonine | 1971 |
Serine biosynthesis in Tetrahymena pyriformis S.
Topics: Acetates; Acyltransferases; Alanine; Aldehyde-Lyases; Animals; Carbon Isotopes; Citric Acid Cycle; Fatty Acids; Formates; Glucose; Glutamates; Glycine; Ketoglutaric Acids; Lactates; Protein Biosynthesis; Pyruvates; Serine; Tetrahymena pyriformis; Threonine | 1971 |
The effect of diethyl- -fluoroglutarate on phosphates and glutamate in slices of rabbit cerebral cortex.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Esters; Fluorine; Glucose; Glutamate Dehydrogenase; Glutamates; Glutamine; Glutarates; Glycine; Oxidative Phosphorylation; Phosphates; Rabbits; Serine; Threonine | 1972 |
The effect of topical application of diethyl- -fluoroglutarate on the metabolism and electrical activity in vivo of cat cerebral cortex.
Topics: Adenosine Triphosphate; Alanine; Aminobutyrates; Ammonia; Animals; Aspartic Acid; Cats; Cerebral Cortex; Electric Stimulation; Electroencephalography; Esters; Fluorine; Glucose; Glucosephosphates; Glutamates; Glutamine; Glutarates; Glycine; Lactates; Malates; Pyruvates; Serine; Synapses; Thalamic Nuclei; Threonine | 1972 |
Calf brain phosvitin kinase. Purification of the kinase associated with a phosphate-incorporating protein.
Topics: Adenosine Triphosphate; Ammonium Sulfate; Animals; Calcium Phosphates; Caseins; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Dialysis; Filtration; Histones; Liver; Nerve Tissue Proteins; Nucleoproteins; Phosphoproteins; Phosphoric Acids; Phosphorus Isotopes; Phosphotransferases; Rats; Serine; Structure-Activity Relationship; Threonine | 1972 |
Studies on the carbohydrate units of thyroglobulin. Evaluation of their microheterogeneity in the human and calf proteins.
Topics: Animals; Asparagine; Carbohydrates; Cattle; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Fucose; Galactose; Glucosamine; Glycopeptides; Hexosamines; Humans; Hydrogen-Ion Concentration; Mannose; Neuraminic Acids; Oligosaccharides; Pronase; Serine; Species Specificity; Sulfites; Threonine; Thyroglobulin | 1972 |
Inactivation of serine transhydroxymethylase and threonine aldolase activities.
Topics: Acetaldehyde; Acetamides; Aldehyde-Lyases; Ammonium Sulfate; Animals; Bromine; Calcium Phosphates; Chemical Precipitation; Chlorine; Enzyme Activation; Gels; Glycine; Iodoacetates; Kinetics; Liver; Pyruvates; Rabbits; Serine; Stereoisomerism; Tetrahydrofolates; Threonine; Transferases | 1972 |
Amino acid metabolism during starvation in human pregnancy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Blood Glucose; Female; Food Deprivation; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Isoleucine; Leucine; Pregnancy; Serine; Starvation; Threonine; Time Factors; Valine | 1972 |
[Indole formation in Klebsiella oxytoca: dependence of the metabolite formation of the oxygen tension].
Topics: Anaerobiosis; Bacillus; Indoles; Klebsiella; Oxygen; Partial Pressure; Serine; Threonine; Tryptophan | 1972 |
The aminoaciduria of pregnancy.
Topics: Alanine; Amino Acids; Female; Folic Acid; Glycine; Histidine; Humans; Kidney; Pregnancy; Renal Aminoacidurias; Serine; Statistics as Topic; Threonine | 1972 |
[Specific method for the detection of threonine and allo-threonine on thin-layer (and paper) chromatograms].
Topics: Chromatography; Chromatography, Paper; Chromatography, Thin Layer; Colorimetry; Fluorescence; Hot Temperature; Humidity; Indicators and Reagents; Serine; Threonine; Time Factors | 1972 |
Characteristics of amino acid accumulation by synaptosomal particles isolated from rat brain.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Carbon Isotopes; Leucine; Lysine; Nerve Endings; Ouabain; Potassium; Proline; Rats; Serine; Sodium; Stimulation, Chemical; Synaptic Vesicles; Synaptosomes; Threonine; Tyrosine; Valine | 1972 |
Amino acid, creatine and creatinine studies in myotonic dystrophy.
Topics: Adult; Age Factors; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Creatinine; Erythrocytes; Female; Glutamine; Glycine; Hemolysis; Humans; Male; Membranes; Middle Aged; Myotonic Dystrophy; Ornithine; Permeability; Serine; Threonine | 1972 |
Influence of monovalent cations on the activity of L-serine (L-threonine) dehydratase from rat liver. The control of threonine-serine activity ratio.
Topics: Ammonium Chloride; Ammonium Sulfate; Animals; Apoproteins; Binding Sites; Chloromercuribenzoates; Drug Stability; Enzyme Induction; Hot Temperature; Hydro-Lyases; Kinetics; L-Serine Dehydratase; Liver; Male; Potassium Chloride; Protein Binding; Pyridoxal Phosphate; Rats; Serine; Threonine | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
Phosphorylation of ribosomal proteins in sarcoma 180 tumor cells.
Topics: Animals; Blood Proteins; Centrifugation, Density Gradient; Electrophoresis; Female; Kinetics; Mice; Molecular Weight; Neoplasm Proteins; Phosphates; Phosphoproteins; Phosphorus Isotopes; Reticulocytes; Ribosomes; Sarcoma 180; Serine; Sodium Dodecyl Sulfate; Species Specificity; Threonine | 1972 |
Plasma amino acid response in young men given diets devoid of single essential amino acids.
Topics: Adolescent; Adult; Amino Acids; Deficiency Diseases; Dietary Proteins; Fasting; Female; Humans; Isoleucine; Leucine; Lysine; Male; Nutritional Physiological Phenomena; Nutritional Requirements; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1972 |
Synthesis of serine by the dog kidney in vivo.
Topics: Animals; Carbon Isotopes; Dogs; Glutamine; Glycine; Kidney; Renal Artery; Renal Veins; Serine; Threonine | 1972 |
[Chemical and submicroscopic structure of the cell walls of the ascomycete Chaetomium globosum].
Topics: Amino Sugars; Ascomycota; Aspartic Acid; Binding Sites; Cell Wall; Chemical Phenomena; Chemistry; Chitin; Histocytochemistry; Lipopolysaccharides; Microscopy, Electron; Polysaccharides; Serine; Threonine | 1972 |
[Isolation of bronchial mucins secreted in cystic fibrosis].
Topics: Animals; Bronchi; Child; Chromatography, Gel; Chromatography, Ion Exchange; Cystic Fibrosis; Electrophoresis; Fucose; Galactose; Hexosamines; Humans; Hydrogen-Ion Concentration; Immunoelectrophoresis; Mucins; Mucus; Neuraminic Acids; Rabbits; Serine; Sputum; Sulfuric Acids; Threonine | 1972 |
Specific O-acylation of hydroxylamino acids in presence of free amino groups.
Topics: Acetates; Acylation; Amino Acids; Animals; Carboxylic Acids; Cattle; Chemical Phenomena; Chemistry; Chlorine; Drug Stability; Fluoroacetates; Insulin; Pancreas; Peptides; Ribonucleases; Serine; Spectrophotometry; Threonine; Tyrosine; Ultraviolet Rays | 1972 |
Glycoprotein coat of the TA3 cell. Isolation and partial characterization of a sialic acid containing glycoprotein fraction.
Topics: Acetates; Adenocarcinoma; Amino Acids; Animals; Cell Membrane; Chromatography, Gel; Galactosamine; Galactose; Glucosamine; Glycoproteins; Guanidines; Macromolecular Substances; Mammary Neoplasms, Experimental; Mice; Molecular Weight; Neuraminic Acids; Serine; Threonine; Trypsin; Ultracentrifugation | 1972 |
Threonine dehydratase from goat liver.
Topics: Ammonium Sulfate; Animals; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Cysteine; Goats; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; Liver; Pyridoxal Phosphate; Serine; Threonine | 1972 |
Endocrine control of free amino acids content in uterine fluid in pregnant rabbits.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Body Fluids; Castration; Corpus Luteum; Embryo Implantation; Estradiol; Female; Glycine; Ovary; Pregnancy; Progesterone; Rabbits; Serine; Taurine; Threonine; Uterus | 1972 |
N-acylsuccinimides as acylating agents for proteins: the selective acylation of lysine residues.
Topics: Acylation; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Pyrrolidinones; Serine; Succinimides; Threonine | 1972 |
Effects of imidazoleacetic acid on brain amino acids and body temperature in mice.
Topics: Acetates; Amino Acids; Animals; Aspartic Acid; Body Temperature; Brain; Brain Chemistry; Glutamates; Glutamine; Hypothalamus; Imidazoles; Male; Mice; Serine; Threonine | 1972 |
Protein kinase and specific phosphate acceptor proteins associated with vaccinia virus cores.
Topics: Adenosine Triphosphate; Cations, Divalent; Centrifugation, Zonal; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Magnesium; Molecular Weight; Oxidative Phosphorylation; Peptides; Phosphorus Isotopes; Phosphotransferases; Potassium; Serine; Surface-Active Agents; Tartrates; Threonine; Trichloroacetic Acid; Vaccinia virus; Viral Proteins | 1972 |
[Amino acid sequence of the threonine containing mureins of some species of Streptococcus].
Topics: Alanine; Amino Acid Sequence; Cell Wall; Chromatography, Paper; Chromatography, Thin Layer; Glycine; Peptidoglycan; Phosphates; Serine; Streptococcus; Threonine | 1972 |
Studies on gastric mucoproteins. The production of radioactive mucoproteins by pig gastric mucosal scrapings in vitro.
Topics: Animals; Carbohydrate Metabolism; Carbon Isotopes; Centrifugation, Density Gradient; Gastric Mucosa; Glucose; Hydrogen-Ion Concentration; In Vitro Techniques; Mucoproteins; Oxygen Consumption; Pronase; Proteins; Serine; Solubility; Sulfates; Swine; Threonine; Tritium; Water | 1972 |
Phosphoprotein kinases from rat liver cytosol.
Topics: Animals; Autoradiography; Caseins; Cell Nucleus; Chromatin; Chromatography, Gel; Cytosol; Egg Proteins; Electrophoresis; Histones; Kinetics; Liver; Phosphoproteins; Phosphorus Isotopes; Phosphotransferases; Protamines; Proteins; Rats; Serine; Threonine; Trypsin | 1972 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Effect of dietary protein level on plasma free amino acids in the chicken.
Topics: Alanine; Amino Acids; Animals; Blood; Body Weight; Caseins; Chickens; Depression, Chemical; Dietary Proteins; Glycine; Isoleucine; Leucine; Lysine; Male; Methionine; Proline; Proteins; Serine; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1971 |
The protein and lipid composition of arterial elastin and its relationship to lipid accumulation in the atherosclerotic plaque.
Topics: Adolescent; Adult; Aged; Aorta; Arginine; Arteriosclerosis; Aspartic Acid; Cholesterol; Elastin; Esters; Female; Glutamates; Histidine; Humans; Lipids; Lung; Lysine; Male; Middle Aged; Phospholipids; Proteins; Serine; Threonine; Triglycerides; Tritium | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
A study of the amino-acids in urine from dogs with cystine urolithiasis.
Topics: Animals; Arginine; Chromatography; Cystinuria; Dog Diseases; Dogs; Lysine; Male; Nitrogen; Ornithine; Renal Aminoacidurias; Serine; Threonine; Urinary Calculi | 1971 |
Quantitative protein sequencing using mass spectrometry: mass spectral analysis of 2-anilino-5-thiazolinone derivatives of amino acids without prior conversion to the phenyl thiohydantoins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry; Drug Stability; Glutamates; Hydantoins; Lysine; Mass Spectrometry; Methods; Phenylalanine; Ribonucleases; Serine; Sulfides; Thiazoles; Thiocyanates; Threonine; Tyrosine | 1971 |
Daily variations in the concentrations of individual amino acids in rat plasma.
Topics: Alanine; Amino Acids; Animals; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Comparison of amino acid concentrations between plasma and erythrocytes. Studies in normal human subjects and those with metabolic disorders.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Aspartic Acid; Biological Transport; Child; Chromatography, Ion Exchange; Cystine; Erythrocytes; Glutamates; Glutathione; Glycine; Histidine; Homocystine; Homocystinuria; Humans; Infant; Maple Syrup Urine Disease; Methionine; Ornithine; Phenylketonurias; Plasma; Renal Tubular Transport, Inborn Errors; Serine; Spectrophotometry; Threonine; Tyrosine | 1971 |
Studies on the conformation of amino acids. IV. Conformations of serine, threonine, cysteine, and valine.
Topics: Amino Acids; Chemical Phenomena; Chemistry, Physical; Cysteine; Models, Structural; Serine; Thermodynamics; Threonine; Valine | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
The purification and properties of the glycoproteins of pig gallbladder bile.
Topics: Amino Acids; Animals; Bile; Blood Group Antigens; Borohydrides; Butyrates; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Ethanol; Fucose; Galactosamine; Galactose; Gallbladder; Glucosamine; Glucose; Hemagglutination Tests; Hexosamines; Hydrogen-Ion Concentration; Isoelectric Focusing; Keto Acids; Kinetics; Mannose; Mucins; Neuraminic Acids; Oxidation-Reduction; Pronase; Pyruvates; Serine; Threonine | 1971 |
The amino acid-fermenting clostridia.
Topics: Amino Acids; Arginine; Caseins; Chromatography, Paper; Clostridium; Culture Media; Fermentation; Glucose; Glutamates; Glycine; Histidine; Proline; Serine; Threonine | 1971 |
Identification of one of the L-serine dehydratase isoenzymes from rat liver as L-homoserine dehydratase.
Topics: Animals; Centrifugation, Density Gradient; Chromatography, Gel; Cystathionine; Cysteine; Cystine; Female; Homoserine; Hydro-Lyases; Isoenzymes; L-Serine Dehydratase; Liver; Molecular Weight; Rats; Serine; Threonine | 1971 |
Effect of substrate structure on coupling ratio for Na + -dependent transport of amino acids.
Topics: Alanine; Amino Acids; Animals; Asparagine; Biological Transport; Carbon Isotopes; Columbidae; Cysteine; Erythrocytes; Hydroxyproline; Kinetics; Models, Biological; Models, Structural; Potassium; Potassium Isotopes; Proline; Serine; Sodium; Sodium Chloride; Sodium Isotopes; Structure-Activity Relationship; Threonine; Tritium | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Carbohydrate metabolism in pregnancy. IX. Plasma levels of gluconeogenic fuels during fasting in the rat.
Topics: Alanine; Amino Acids; Animals; Carbohydrate Metabolism; Fasting; Female; Gluconeogenesis; Glutamates; Glutamine; Glycerol; Hypoglycemia; Lactates; Pregnancy; Pyruvates; Rats; Serine; Threonine; Time Factors | 1971 |
Isolation and fractionation of glycopeptides from porcine thyroglobulin.
Topics: Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis; Fucose; Galactose; Glucosamine; Glycopeptides; Mannose; Molecular Weight; Neuraminic Acids; Peptides; Polysaccharides; Pronase; Serine; Swine; Threonine; Thyroglobulin | 1971 |
Structure of glycoproteins of human erythrocytes. Alkali-stable oligosaccharides.
Topics: Alkalies; Aspartic Acid; Borohydrides; Chromatography, Gel; Erythrocytes; Fucose; Galactose; Glucosamine; Glucosidases; Glycine; Glycopeptides; Glycoproteins; Humans; Hydrolysis; Mannose; Models, Structural; Molecular Weight; Neuraminic Acids; Oligosaccharides; Serine; Threonine | 1971 |
[Dissociation of S- and P-variants of Bacillus brevis var. G.-B. on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Mutation; Nitrogen; Ornithine; Phenylalanine; Serine; Stimulation, Chemical; Threonine; Time Factors; Tryptophan; Valine | 1971 |
Concentration dependence of vapor pressure isotope effect of methylamine and N-deuteriomethylamine in hexane.
Topics: Energy Transfer; Kinetics; Protons; Serine; Threonine | 1971 |
[Antineoplastic effect and chemical structure of protamines of various origin].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Depression, Chemical; Fishes; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Leukemia, Experimental; Lysine; Methionine; Mice; Proline; Protamines; Sarcoma 37; Serine; Threonine | 1971 |
Isolation of 32 P-labelled phosphorylserine and phosphoryl-threonine from Ehrlich mouse-ascites tumour cells, suspended in an isotoic medium, containing 32 P-labelled nucleoside triphosphates or inorganic pyrophosphates.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Guanosine Triphosphate; Hydrolysis; In Vitro Techniques; Mice; Nucleotides; Phosphates; Phosphorus Isotopes; Proteins; Serine; Threonine; Time Factors | 1971 |
The proteinaceous, gum polysaccharide from Azadirachta indica A. Juss.
Topics: Amino Acids; Amino Sugars; Aspartic Acid; Chromatography, Gel; Dithiothreitol; Plant Proteins; Polysaccharides; Resins, Plant; Serine; Threonine; Trees | 1971 |
Mass spectrometry of glycoproteins: O-glycosyl derivatives of L-serine and L-threonine.
Topics: Amino Sugars; Esters; Glycoproteins; Mass Spectrometry; Serine; Spectrum Analysis; Stereoisomerism; Threonine | 1971 |
Studies on the interactions between purified bovine caseins and alkaline-earth-metal ions.
Topics: Animals; Aspartic Acid; Barium; Calcium; Calcium Isotopes; Caseins; Cattle; Chromatography, DEAE-Cellulose; Dialysis; Electrophoresis; Gels; Glutamates; Magnesium; Phosphates; Protein Binding; Radioisotopes; Serine; Starch; Strontium; Strontium Isotopes; Threonine | 1971 |
[L-hydroxyamino acid(L-serine, L-threonine)-sulfate sulfatase activity in the serum and human tissue].
Topics: Humans; Serine; Sulfatases; Threonine | 1971 |
Similarities and differences among specific tRNA's in mammalian tissues.
Topics: Alanine; Animals; Brain Chemistry; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cattle; Chick Embryo; Culture Techniques; Fibroblasts; Glycine; HeLa Cells; Humans; Kidney; Leucine; Liver; Lysine; Mice; Muscles; Neoplasms, Experimental; Phenylalanine; Rabbits; RNA, Transfer; Serine; Species Specificity; Threonine; Tritium | 1967 |
A possible ambiguity in the coding of mouse hemoglobin.
Topics: Amino Acid Sequence; Animals; Hemoglobins; Inbreeding; Magnesium; Mice; RNA, Transfer; Serine; Threonine | 1966 |
Amino acid fermentation by Fusobacterium nucleatum.
Topics: Amino Acids; Aspartic Acid; Cysteine; Fermentation; Fusobacterium; Gingiva; Glutamates; Glutamine; Histidine; Humans; Lysine; Methionine; Mouth; Serine; Threonine | 1968 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
[Free serum amino acids in leukosis].
Topics: Adult; Amino Acids; Central Nervous System Diseases; Histidine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lysine; Middle Aged; Serine; Threonine | 1969 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Transfer RNA species in normal and leukemic human lymphoblasts.
Topics: Amino Acids; Carbon Isotopes; Cell Line; Chromatography; Glutamine; Glycine; Humans; Leucine; Leukemia, Lymphoid; Ligases; Lymphocytes; Proline; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine | 1970 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Further studies of the principal glycoprotein from human saliva.
Topics: Amino Acids; Blood Group Antigens; Chromatography; Fucose; Galactosamine; Galactose; Glucosamine; Glucose; Glycoproteins; Humans; Mannose; Neuraminic Acids; Saliva; Serine; Sulfates; Threonine | 1971 |
An unusual calcified tumour of the maxilla. A case report and biochemical study.
Topics: Adolescent; Aspartic Acid; Calcinosis; Chromatography, Ion Exchange; Cystine; Female; Glutamates; Glycine; Humans; Hydroxyproline; Isoleucine; Leucine; Maxilla; Maxillary Neoplasms; Serine; Threonine; X-Ray Diffraction | 1971 |
Effects of ionizing radiation on free amino acids in Oedogonium cardiacum.
Topics: Alanine; Chromatography, Thin Layer; Eukaryota; Glutamates; Glycine; Histidine; Leucine; Methionine; Ornithine; Radiation Effects; Serine; Threonine; Valine | 1966 |
[Studies on ambiguities of the genetic code at the level of the site of recognition of the message].
Topics: Bacterial Proteins; Escherichia coli; Genetic Code; In Vitro Techniques; Isoleucine; Leucine; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Serine; Streptomycin; Threonine; Uracil Nucleotides | 1965 |
Crystalline D-serine dehydrase.
Topics: Chromatography; Crystallization; Escherichia coli; Hydro-Lyases; In Vitro Techniques; Mutation; Serine; Threonine | 1966 |
Enzymatic formation of beta-cyanoalanine from cyanide by Escherichia coli extracts.
Topics: Adenosine Triphosphate; Alanine; Carbon Isotopes; Chemical Phenomena; Chemistry; Cyanides; Cysteine; Escherichia coli; Magnesium; Serine; Sulfides; Threonine | 1965 |
Nonchemotactic mutants of Escherichia coli.
Topics: Aspartic Acid; Cell Biology; Chemotaxis; Coliphages; Escherichia coli; Flagella; Glucose; Hemagglutination Tests; Microscopy, Electron; Mutation; Oxygen; Serine; Threonine | 1967 |
Degeneracy in the amino acid code.
Topics: Amino Acids; Asparagine; Bacterial Proteins; Escherichia coli; Genetic Code; Glutamine; Histidine; Leucine; Lysine; Polynucleotides; Proline; Serine; Threonine | 1966 |
Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure.
Topics: Alanine; Ammonia; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Genes; Glycine; Histidine; Leucine; Methionine; Molecular Biology; Molecular Weight; Peptides; Phenylalanine; Proline; Salmonella typhimurium; Serine; Threonine; Transaminases; Tyrosine; Valine | 1967 |
[Deamination of threonine and serine in Salmonella typhimurium].
Topics: Ammonia; Isoleucine; Keto Acids; Salmonella typhimurium; Serine; Threonine; Valine | 1964 |
Hemoglobins of mice: sequence and possible ambiguity at one position of the alpha chain.
Topics: Amino Acid Sequence; Animals; Chromatography, Ion Exchange; Glycine; Hemoglobins; In Vitro Techniques; Mice; Molecular Biology; Pepsin A; Peptides; Serine; Threonine; Trypsin; Valine | 1967 |
[Endogenous pellagra without hyperaminoaciduria].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Chromatography, Paper; Diagnosis, Differential; Electroencephalography; Glutamates; Glutamine; Hartnup Disease; Histidine; Humans; Lysine; Male; Pellagra; Serine; Skin Manifestations; Threonine | 1969 |
Effect of cold exposure on the response of rats to a dietary amino acid imbalance.
Topics: Adaptation, Physiological; Amino Acids; Animals; Caseins; Cold Temperature; Darkness; Diet; Dietary Proteins; Food Preferences; Growth; Histidine; Hydro-Lyases; L-Serine Dehydratase; Light; Liver; Male; Protein Deficiency; Rats; Serine; Threonine; Time Factors | 1969 |
Hormone-dependent phosphorylation of nuclear proteins during mammary gland differentiation in vitro.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell Differentiation; Culture Techniques; Dactinomycin; Epithelium; Female; Genetics; Histones; Hydrocortisone; Insulin; Mammary Glands, Animal; Mice; Nucleoproteins; Peptide Biosynthesis; Phosphates; Phosphorus Isotopes; Prolactin; RNA; Serine; Stimulation, Chemical; Threonine; Time Factors; Tritium; Uracil Nucleotides | 1969 |
[Model reactions for enzymatic catalysis. II. Further studies on non-enzymatic transamination with 2-formylimidazoles].
Topics: Amino Acids; Ammonia; Aspartic Acid; Catalysis; Cobalt; Copper; Cystine; Formates; Glycine; Hydro-Lyases; Imidazoles; Iron; Models, Chemical; Nickel; Pyruvates; Serine; Threonine; Zinc | 1969 |
Glycopeptide linkages in a phosphomannan peptide from yeast cell walls.
Topics: Cell Wall; Mannose; Peptide Hydrolases; Peptides; Phosphates; Polysaccharides; Saccharomyces; Serine; Threonine | 1969 |
Isolation and properties of a fluorescent pigent from Pseudomonas mildenbergii.
Topics: Bacterial Proteins; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Electrophoresis; Fluorometry; Glutamates; Hydrogen-Ion Concentration; Lysine; Nitrobenzenes; Pigments, Biological; Pseudomonas; Serine; Spectrum Analysis; Thiocyanates; Threonine; Trypsin | 1969 |
Structure studies of collocalia mucoid. I. Carbohydrate and amino acid composition.
Topics: Amino Acids; Aspartic Acid; Carbohydrates; Fucose; Galactose; Glucosamine; Glutamates; Glycoproteins; Hemagglutination Inhibition Tests; Hexosamines; Neuraminic Acids; Orthomyxoviridae; Proline; Serine; Threonine; Valine | 1969 |
Isolation of gastroferrin from human gastric juice.
Topics: Amino Acids; Autoanalysis; Chelating Agents; Chemical Precipitation; Chromatography, Gel; Dialysis; Fucose; Galactose; Gastric Juice; Glucosamine; Glycoproteins; Hexosamines; Humans; Hydroxides; Iron; Iron-Binding Proteins; Methods; Molecular Weight; Neuraminic Acids; Proline; Protein Binding; Proteins; Serine; Threonine; Ultracentrifugation | 1969 |
Changes in free amino acids of tomato fruit under pathogenesis.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Fruit; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Plant Diseases; Serine; Threonine; Tyrosine; Valine | 1969 |
A lithium buffer system for single-column amino acid analysis.
Topics: Amino Acids; Asparagine; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Glutamine; Hot Temperature; Indicators and Reagents; Lithium; Serine; Threonine | 1969 |
Effect of protein and riboflavin on plasma amino acids and hepatic riboflavin-coenzymes in the rat.
Topics: Amino Acids; Analysis of Variance; Animals; Body Weight; Caseins; Depression, Chemical; Diet; Dietary Proteins; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glutens; Glycine; Liver; Lysine; Male; Metabolism; Rats; Riboflavin; Serine; Stimulation, Chemical; Threonine; Triticum | 1969 |
Transaminase activity in sheep rumen content.
Topics: Alanine; Alanine Transaminase; Animals; Arginine; Aspartic Acid; Cysteine; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methionine; Phenylalanine; Rumen; Serine; Sheep; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Chemical and physico-chemical properties of placental protein with antineoplastic effect].
Topics: Alanine; Amino Acids; Ammonia; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Female; Glutamates; Glycine; Histidine; Humans; Leucine; Lysine; Phenylalanine; Placenta; Proline; Proteins; Serine; Threonine; Tyrosine; Valine | 1969 |
Study on the amino acid composition in the cornea of hypophysectomized rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cornea; Cystine; Electrophoresis; Glutamates; Glycine; Growth Hormone; Histidine; Hypophysectomy; Leucine; Lysine; Methionine; Phenylalanine; Pituitary Gland; Rats; Serine; Threonine; Tyrosine | 1969 |
The destruction of serine and threonine during acid hydrolysis.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Hydrochloric Acid; Hydrolysis; Kinetics; Mucins; Serine; Submandibular Gland; Threonine | 1969 |
Amino acid content of muscle and plasma with altered pH.
Topics: Acidosis, Respiratory; Alanine; Alkalosis; Amino Acids; Animals; Aspartic Acid; Carbon Dioxide; Cell Membrane; Citrulline; Extracellular Space; Glutamine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Male; Muscles; Partial Pressure; Potassium Deficiency; Rats; Serine; Threonine; Valine | 1970 |
Glycopeptides from earthworm cuticle collagen.
Topics: Acetates; Amino Acids; Animals; Annelida; Aspergillus; Carbohydrates; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Collagen; Galactosidases; Glycoproteins; Hexosamines; Hydrogen-Ion Concentration; Methods; Oligosaccharides; Peptides; Plants; Quaternary Ammonium Compounds; Serine; Skin; Sodium Chloride; Solubility; Threonine | 1970 |
Pyridoxine and pyridoxal analogs. 13. A nuclear magnetic resonance study of the condensation of polyfunctional amino acids with pyridoxal.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cycloserine; Histidine; Homocysteine; Homocystine; Imidazoles; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Serine; Threonine | 1970 |
Biosynthesis of amino acids in Clostridium pasteurianum.
Topics: Alcohol Oxidoreductases; Amino Acids; Aspartic Acid; Carbon Isotopes; Clostridium; Glucose; Glutamates; Glycine; Phosphoglycerate Kinase; Pyruvates; Serine; Threonine; Transaminases | 1970 |
Levels of amino acids and proteins in Pacinian corpuscles of the cat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Chromatography, Paper; Denervation; Glutamates; Glutamine; Glycine; Mesentery; Nerve Endings; Nerve Tissue Proteins; Pargyline; Reserpine; Serine; Threonine | 1970 |
The chemical composition and function of gastrointestinal mucus.
Topics: Amino Acids; Blood Group Antigens; Chromatography; Galactose; Gastric Mucins; Gastric Mucosa; Glucosamine; Glycoproteins; Humans; Intestinal Mucosa; Molecular Weight; Mucus; Serine; Sulfates; Threonine; Ultracentrifugation | 1970 |
[Oxidation of N-acetylserine and -threonine derivatives with lead (IV) acetate].
Topics: Acetates; Chemical Phenomena; Chemistry; Lead; Oxidation-Reduction; Serine; Threonine | 1970 |
Derivation of partial sequence of human beta chain messenger RNA from mutation data.
Topics: Alanine; Arginine; Genetic Code; Glycine; Hemoglobins; Humans; Leucine; Mutation; Nucleotides; Proline; RNA, Messenger; Serine; Threonine; Valine | 1970 |
Molecular weight and amino acid composition of five-times-crystallized phosphoglucose isomerase from rabbit skeletal muscle.
Topics: Amides; Amino Acids; Animals; Barium; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Crystallization; Cysteine; Diffusion; Glucose-6-Phosphate Isomerase; Hydrochloric Acid; Hydroxides; Molecular Weight; Muscles; Nitrogen; Oxygen; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Ultracentrifugation; Viscosity | 1970 |
[2,3-dihydroxybenzoic acid and its amino acid derivatives in the culture medium of Klebsiella oxytoca].
Topics: Benzoates; Chromatography, Paper; Culture Media; Depression, Chemical; Esters; Fluorescence; Gluconates; Glucose; Indicators and Reagents; Klebsiella; Nucleosides; Serine; Threonine; Tryptophan; Ultraviolet Rays | 1970 |
Crystalline threonine aldolase from Candida humicola.
Topics: Acetaldehyde; Aldehyde-Lyases; Candida; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Electrophoresis, Disc; Glycine; Hydrogen-Ion Concentration; Methods; Molecular Weight; Pyridoxal Phosphate; Serine; Spectrum Analysis; Threonine; Ultracentrifugation; Ultraviolet Rays | 1970 |
Homoserine dehydrogenase of Pseudomonas putida. Properties and regulation.
Topics: Alcohol Oxidoreductases; Amino Acids; Cell Division; Culture Media; Densitometry; Depression, Chemical; Drug Stability; Enzyme Repression; Feedback; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Methionine; Potassium Chloride; Pseudomonas; Serine; Threonine; Time Factors | 1970 |
[Study of chemical composition and antineoplastic effect of protamines isolated from the milt of sturgeon fishes].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Thin Layer; Depression, Chemical; Electrophoresis; Fishes; Glutamates; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Nucleic Acids; Proline; Protamines; Sarcoma 37; Serine; Spectrum Analysis; Sulfates; Threonine; Ultraviolet Rays | 1970 |
Circadian ythm of human urinary amino acid excretion in fed and fasted states.
Topics: 17-Hydroxycorticosteroids; Adult; Alanine; Amino Acids; Asparagine; Circadian Rhythm; Cystinuria; Fasting; Feeding Behavior; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1970 |
[Biosynthesis of gramicidin C on synthetic media with amino acids as the only N source].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrothricin; Valine | 1970 |
The structure of a phytohemagglutinin receptor site from human erythrocytes.
Topics: Aspartic Acid; Binding Sites; Boron Compounds; Cell Membrane; Chromatography; Chromatography, Gel; Erythrocytes; Galactose; Glucosamine; Humans; Lectins; Mannose; Molecular Weight; Neuraminic Acids; Oligosaccharides; Oxidation-Reduction; Peptide Hydrolases; Peptides; Protein Binding; Serine; Threonine; Trypsin | 1970 |
Droplet countercurrent chromatography.
Topics: Alanine; Amino Acids; Chromatography; Countercurrent Distribution; Cystine; Dinitrophenols; Fluorocarbon Polymers; Ornithine; Proline; Serine; Threonine | 1970 |
Uptake of individual amino acids by perfused rat liver: effect of acute uremia.
Topics: Amino Acids; Animals; Fasting; Female; Glutamates; Isoleucine; Leucine; Liver; Lysine; Perfusion; Protein Biosynthesis; Rats; Serine; Threonine; Uremia; Valine | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
Amino acid sequence analysis with methyl isothiocyanate. Resolution of the methylthiohydantoins by gas-liquid partition chromatography.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Bence Jones Protein; Cattle; Chromatography, Gas; Cysteine; Dipeptides; Glutamates; Hydantoins; Indicators and Reagents; Insulin; Methods; Serine; Serum Albumin, Bovine; Solvents; Thiocyanates; Threonine | 1970 |
Histidinemia.
Topics: Acetates; Acrylates; Adolescent; Alanine; Glycine; Histidine; Humans; Imidazoles; Lactates; Lyases; Male; Metabolism, Inborn Errors; Purpura, Thrombocytopenic; Pyruvates; Serine; Threonine | 1970 |
Attempts of chemical modification of threonine and serine residues in RNase A.
Topics: Amino Acid Sequence; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Circular Dichroism; Dimethyl Sulfoxide; Indicators and Reagents; Pancreas; Ribonucleases; Serine; Threonine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Casein. IX. Carbohydrate moiety of k-casein.
Topics: Carbohydrates; Caseins; Chemical Phenomena; Chemistry; Galactose; Glycoproteins; Hexosamines; Molecular Weight; Neuraminic Acids; Polysaccharides; Serine; Threonine | 1970 |
Amino acid permeability of pea chloroplasts as measured by osmotically determined reflection coefficients.
Topics: Alanine; Amides; Amino Acids; Cell Membrane Permeability; Chloroplasts; Glycine; Imines; Isoleucine; Leucine; Methionine; Osmolar Concentration; Osmotic Pressure; Phenylalanine; Plants; Proline; Serine; Sucrose; Threonine; Valine | 1970 |
Indications of spatial relations among structures recognizing amino acids and Na+ at a transport receptor site.
Topics: Alanine; Amino Acids; Animals; Arginine; Binding Sites; Biological Transport; Canavanine; Columbidae; Erythrocytes; Guanidines; Lysine; Models, Biological; Models, Structural; Ornithine; Proline; Propionates; Rabbits; Reticulocytes; Serine; Sodium; Threonine | 1970 |
Glycine formation via threonine and serine aldolase. Its interrelation with the pyruvate formate lyase pathway of one-carbon unit synthesis in Clostridium kluyveri.
Topics: Carbon; Carbon Isotopes; Chemical Phenomena; Chemistry; Clostridium; Formates; Fructose-Bisphosphate Aldolase; Glycine; Hydrogen-Ion Concentration; Lyases; Pyruvates; Serine; Stereoisomerism; Threonine | 1970 |
[Correlation between Parkinsonism symptoms and a disorder in the amino acid metabolism in CNS].
Topics: Amino Acids; Animals; Brain Injuries; Central Nervous System Diseases; Cerebrospinal Fluid; Cysteine; Cystine; Diagnosis, Differential; Glycine; Humans; Parkinson Disease; Parkinson Disease, Postencephalitic; Phenothiazines; Rats; Serine; Threonine; Tremor | 1970 |
A lipoprotein characterizing obstructive jaundice. II. Isolation and partial characterization of the protein moieties of low density lipoproteins.
Topics: Alanine; Albumins; Amino Acids; Chemical Precipitation; Chemistry Techniques, Analytical; Cholestasis; Ethanol; Heparin; Humans; Immunochemistry; Immunoelectrophoresis; Lipoproteins; Peptides; Proteins; Serine; Threonine; Ultracentrifugation | 1970 |
Glutamine in the phenylketonuric central nervous system.
Topics: Adolescent; Adult; Amino Acids; Biological Transport, Active; Brain; Brain Chemistry; Child; Female; Glutamine; Histidine; Humans; Intellectual Disability; Intelligence Tests; Male; Middle Aged; Phenylketonurias; Serine; Threonine; Tyrosine | 1970 |
The occurrence in proteins of the tripeptides Asn-X-Ser and Asn-X-Thr and of bound carbohydrate.
Topics: Amino Acid Sequence; Asparagine; Carbohydrates; Computers; Glycoproteins; Peptides; Proteins; Serine; Statistics as Topic; Threonine | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
[Correlation of biochemical features and pathogenicity of Shigella. I. Respiratory activity in the amino acid metabolism of virulent and avirulent strains of Shigella].
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Guinea Pigs; Oxygen Consumption; Serine; Shigella; Threonine; Time Factors; Virulence | 1970 |
An investigation of the conformational changes in histones F1 and F2a1 by proton magnetic resonance spectroscopy.
Topics: Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Glycine; Histones; Magnetic Resonance Spectroscopy; Muramidase; Optical Rotatory Dispersion; Osmolar Concentration; Papain; Proline; Ribonucleases; Serine; Sodium Chloride; Threonine | 1970 |
Amino acid sequence at the active center of succinate dehydrogenase.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Flavin-Adenine Dinucleotide; Flavins; Histidine; Myocardium; Peptides; Serine; Succinate Dehydrogenase; Thiocyanates; Threonine; Valine | 1970 |
Effect of vitamin B6 depletion in adult man on the plasma concentration and the urinary excretion of free amino acids.
Topics: Adult; Alanine; Amino Acids; Fasting; Glycine; Humans; Isoleucine; Leucine; Male; Pyridoxine; Serine; Threonine; Valine; Vitamin B 6 Deficiency | 1971 |
Phosphoprotein kinases associated with rat liver chromatin.
Topics: Animals; Caseins; Cattle; Cellulose; Chromatography; Chromatography, Gel; Chromosomes; Liver; Nucleoproteins; Phosphoric Acids; Phosphorus Isotopes; Phosphotransferases; Proteins; Rats; Serine; Threonine | 1971 |
Reaction of tobacco mosaic virus with maleic anhydride and some possible applications to x-ray diffraction analysis.
Topics: Amino Acids; Anhydrides; Autoradiography; Binding Sites; Carbon Isotopes; Centrifugation; Chemical Phenomena; Chemistry; Densitometry; Electrophoresis; Hydrogen-Ion Concentration; Hydrolysis; Hydroxylamines; Lysine; Maleates; Peptides; Serine; Spectrophotometry; Threonine; Tobacco Mosaic Virus; Trypsin; Tyrosine; Ultracentrifugation; Ultraviolet Rays; Viral Proteins; X-Ray Diffraction | 1971 |
Physiological studies of biosynthetic indole excretion in Bacillus alvei.
Topics: Acrylates; Amino Acids; Ammonia; Autoanalysis; Bacillus; Caseins; Cell-Free System; Colorimetry; Culture Media; Genetics, Microbial; Hydro-Lyases; Indicators and Reagents; Indoles; L-Serine Dehydratase; Models, Theoretical; Mutation; ortho-Aminobenzoates; Serine; Spectrophotometry; Stereoisomerism; Threonine; Tryptophan | 1971 |
Studies on the conformation of amino acids. IX. Conformations of butyl, seryl, threonyl, cystennyl, and valyl residues in a dipeptide unit.
Topics: Amino Acids; Butylamines; Cysteine; Dipeptides; Energy Transfer; Serine; Threonine; Valine | 1971 |
[The flagellar apparatus of Rhodopseudomonas palustris. VI. Characterization of flagellin].
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Electrophoresis; Flagella; Gels; Glycine; Leucine; Molecular Weight; Pseudomonas; Serine; Threonine; Ultracentrifugation | 1971 |
Nutrient media for plant-parasitic nematodes. II. Amino acid requirements of Aphelenchoides sp.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Fungi; Germ-Free Life; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
[Dissociation of R- and P plus-variants of Bacillus brevis var. G.-B. during growth on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Valine | 1971 |
Lung connective tissue measurements. I. Amino acid analysis procedures for determination of canine lung connective tissue.
Topics: Animals; Aspartic Acid; Autoanalysis; Chromatography, Ion Exchange; Collagen; Connective Tissue; Dogs; Elastin; Glutamates; Hydroxyproline; Lung; Lysine; Proline; Pulmonary Fibrosis; Radiation Injuries, Experimental; Serine; Threonine | 1971 |
Serine transhydroxymethylase. Affinity of the active site for substrates, substrate analogues, and anions.
Topics: Alanine; Aldehydes; Aminoisobutyric Acids; Animals; Benzoates; Binding Sites; Chlorides; Cysteamine; Cysteine; Electrophoresis; Folic Acid; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Models, Biological; Organophosphonates; Phosphates; Potassium; Propionates; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Stereoisomerism; Sulfates; Sulfhydryl Compounds; Sulfonic Acids; Thermodynamics; Threonine; Transferases; Ultracentrifugation | 1971 |
The uptake of various amino acids by the mouse brain in vivo.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Brain; Glycine; Histidine; Isoleucine; Methionine; Mice; Serine; Threonine; Time Factors; Tryptophan; Valine | 1971 |
The influence of various -alkyl and -hydroxyalkyl substituents on the stability of dipeptides in dilute alkali.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Borates; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Dipeptides; Drug Stability; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Kinetics; Leucine; Potassium; Serine; Stereoisomerism; Threonine; Valine | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Metabolism of amino acids in plants. I. Changes in the soluble amino acid fractions of bushbean seedlings (Phaseolus vulgaris L.) and the development of transaminase activity.
Topics: Alanine; Alanine Transaminase; Amino Acids; Asparagine; Aspartate Aminotransferases; Cadmium; Chromatography, Paper; Colorimetry; Darkness; Indenes; Ketones; Light; Nitrogen; Plant Development; Plant Physiological Phenomena; Plant Proteins; Plants; Radiation Effects; Seeds; Serine; Solubility; Threonine; Time Factors; Transaminases; Trichloroacetic Acid; Valine | 1971 |
Molecular transport. I. In vivo studies of transport mutants of Neurospora crassa with altered amino acid competition patterns.
Topics: Alanine; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Crosses, Genetic; Genetics, Microbial; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Serine; Stereoisomerism; Threonine; Tyrosine; Valine | 1971 |
Mutation of Saccharomyces cerevisiae preventing uptake of S-adenosylmethionine.
Topics: Adenine; Carbon Isotopes; Colorimetry; Crosses, Genetic; Culture Media; Cysteine; Genetics, Microbial; Homocysteine; Methionine; Mutation; Nucleosides; S-Adenosylmethionine; Saccharomyces; Serine; Threonine | 1971 |
Vitamin B12 deficiency in the rat fed high protein rations.
Topics: Amino Acids; Animals; Caseins; Depression, Chemical; Dietary Proteins; Formates; Glycine; Growth; Isoleucine; Male; Malonates; Nitrogen; Proline; Propionates; Rats; Serine; Stereoisomerism; Threonine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1971 |
The free amino acid concentrations in maternal and foetal plasmas in the pregnant ewe.
Topics: Alanine; Amino Acids; Animals; Chromatography, Ion Exchange; Female; Fetus; Glycine; Maternal-Fetal Exchange; Pregnancy; Pregnancy, Animal; Serine; Sheep; Threonine; Umbilical Arteries; Umbilical Veins | 1971 |
Esters of serine and threonine in hydrolysates of histones and protamines, and attendant errors in amino acid analyses of proteins.
Topics: Activation Analysis; Amino Acids; Animals; Autoanalysis; Cattle; Chickens; Electrophoresis; Erythrocytes; Histones; Protamines; Protein Hydrolysates; Rabbits; Serine; Spectrum Analysis; Sulfates; Threonine; Thymus Gland | 1967 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
[Chemistry of the antibiotic A-128 (neotelomycin)--qualitative and quantitative amino acid composition].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Chemistry Techniques, Analytical; Chromatography, Paper; Electrophoresis; Glycine; Proline; Serine; Threonine; Tryptophan | 1967 |
[Differentiation of aliphatic dipeptidases from cod muscle].
Topics: Animals; Cellulose; Chromatography, Ion Exchange; Dipeptidases; Dipeptides; Fishes; Glycine; Hot Temperature; Kinetics; Leucine; Methionine; Muscles; Phenylalanine; Protein Denaturation; Serine; Spectrophotometry; Threonine; Valine; Zinc | 1967 |
[Hyperaminoaciduria in children suffering from progressive muscular dystrophy].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Child; Child, Preschool; Creatine; Creatinine; Female; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Muscular Dystrophies; Nitrogen; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
Studies on glycoproteins. XVI. Serine and threonine residues., the only identifiable sugar acceptors in ovine submaxillary gland glycoprotein.
Topics: Amino Acids; Animals; Autoanalysis; Binding Sites; Chromatography, Gel; Glycoproteins; Hexosamines; Peptides; Protein Binding; Serine; Sheep; Submandibular Gland; Threonine | 1967 |
Amino acid requirements for growth of the rabbit blastocyst in vitro.
Topics: Amino Acids; Animals; Arginine; Culture Media; Female; Glycine; Histidine; In Vitro Techniques; Leucine; Lysine; Methionine; Ovum; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
The reversible inactivation of L-threonine hydratase of sheep liver by L-serine.
Topics: Animals; Binding Sites; Coenzymes; Dialysis; Hydro-Lyases; Hydrogen-Ion Concentration; In Vitro Techniques; Ketoglutaric Acids; Kinetics; Liver; Oxazoles; Phosphates; Potassium; Potassium Chloride; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Sheep; Threonine; Time Factors | 1968 |
D-galactose di- and trisaccharides from the earthworm cuticle collagen.
Topics: Animals; Annelida; Chromatography, Gel; Collagen; Galactose; Oligosaccharides; Optical Rotatory Dispersion; Serine; Threonine | 1968 |
Two trypsin inhibitors from porcine pancreatic juice.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Enzyme Precursors; Glutamates; Glutamine; Guanidines; In Vitro Techniques; Kallikreins; Molecular Weight; Pancreatic Juice; Proline; Serine; Species Specificity; Spectrum Analysis; Swine; Threonine; Trypsin; Trypsin Inhibitors; Ultracentrifugation; Ultraviolet Rays | 1968 |
Associations among food and protein intake, serine dehydratase, and plasma amino acids.
Topics: Adaptation, Physiological; Amino Acids; Animals; Dietary Proteins; Homeostasis; Hydro-Lyases; Isoleucine; L-Serine Dehydratase; Leucine; Liver; Male; Nutritional Physiological Phenomena; Rats; Serine; Threonine; Valine | 1968 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |
The molecular structures of vertebrate skin collagens. A comparative study.
Topics: Amino Acids; Animals; Anura; Arginine; Autoanalysis; Biological Evolution; Cattle; Chemical Phenomena; Chemistry, Physical; Chickens; Chromatography; Collagen; Electrophoresis; Fishes; Glutamates; Glycine; Guinea Pigs; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Leucine; Methionine; Optical Rotatory Dispersion; Proline; Serine; Sharks; Skin; Snakes; Solubility; Temperature; Threonine; Valine | 1968 |
Effect of temperature on the Ks for homoserine and the Ki for threonine of homoserine dehydrogenase from Chlamidomonas reinhardti.
Topics: Alcohol Oxidoreductases; Eukaryota; Hot Temperature; Kinetics; Serine; Threonine | 1968 |
Serine dehydratase activity in livers of phlorrhizin-treated rats and the hepatic serine plus threonine concentration.
Topics: Animals; Hydro-Lyases; Liver; Male; Phlorhizin; Rats; Serine; Starvation; Threonine | 1968 |
Isolation and identification of alpha-amino aldehydes in collagen.
Topics: Air Sacs; Alanine; Aldehydes; Amino Alcohols; Animals; Aspartic Acid; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Thin Layer; Collagen; Cyprinidae; Gelatin; Glycine; Hydrazones; Lactones; Lysine; Oxidation-Reduction; Rats; Serine; Skin; Spectrum Analysis; Threonine; Tritium | 1968 |
Studies on blood group substances. I. Purification of active material from hog gastric mucin by specific precipitation with Vicia cracca phytohemagglutinin.
Topics: Adsorption; Amino Acids; Animals; Blood Group Antigens; Chemical Precipitation; Chromatography, Gel; Dialysis; Gastric Mucins; Hemagglutination Inhibition Tests; Lectins; Proline; Serine; Swine; Threonine | 1968 |
Quantitative evaluation of O-glycosidic linkages between sugars and aminoacids in ovine submaxillary gland mucoprotein.
Topics: Amino Acids; Animals; Carbohydrates; Chemical Phenomena; Chemistry, Physical; Disaccharides; Electrophoresis; Gels; Hydrogen-Ion Concentration; Keto Acids; Mucoproteins; Peptide Hydrolases; Peptides; Proteins; Serine; Sheep; Submandibular Gland; Threonine | 1968 |
The distribution of amino acids between erythrocytes and plasma in fetal and maternal blood.
Topics: Alanine; Amino Acids; Biological Transport, Active; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Humans; Infant, Newborn; Isoleucine; Leucine; Maternal-Fetal Exchange; Methionine; Placenta; Plasma; Pregnancy; Serine; Threonine; Valine | 1968 |
Studies of red cell stromal proteins in Tay-Sachs disease.
Topics: Adolescent; Adult; Amino Acids; Cell Membrane; Child, Preschool; Erythrocytes; Female; Glycoproteins; Hexosamines; Humans; Infant; Lipidoses; Lipoproteins; Male; Neuraminic Acids; Proteins; Serine; Threonine | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
[The 2.2.2-trifluor-1-benzyloxycarbonycarbonylamino-ethyl-residue from the protecting group for the hydroxyl groups of the serines and threonines on peptide synthesis].
Topics: Methods; Peptides; Serine; Threonine | 1968 |
The structure of a glycopeptide isolated from the yeast cell wall.
Topics: Aspartic Acid; Carbohydrates; Cell Wall; Chromatography, Paper; Electrophoresis; Glucosamine; Mannose; Molecular Weight; Peptides; Saccharomyces; Serine; Threonine; Ultracentrifugation | 1968 |
Kinetics of the photochemical addition of [35S] cysteine to polynucleotides and nucleic acids.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; DNA; Kinetics; Methionine; Polynucleotides; RNA; Saccharomyces; Serine; Sulfur Isotopes; Threonine; Thymus Gland; Tyrosine; Ultraviolet Rays | 1968 |
The substrate specificity of guinea-pig plasma kallikrein.
Topics: Amides; Animals; Arginine; Chemical Phenomena; Chemistry; Esters; Guinea Pigs; Hydrogen-Ion Concentration; Kallikreins; Kinetics; Lysine; Serine; Threonine; Tyrosine | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Serine transhydroxymethylase. Identification as the threonine and allothreonine aldolases.
Topics: Acetaldehyde; Aldehyde-Lyases; Amino Acids; Animals; Carbon Isotopes; Chemical Precipitation; Chromatography; Chromatography, Gel; Glycine; Hot Temperature; Liver; Methods; Protein Denaturation; Rabbits; Serine; Threonine; Transferases | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
The pyridoxal- and pyridoxal 5'-phosphate-catalysed non-enzymic degradations of l-serine o-sulphate and related compounds.
Topics: Aluminum; Ammonia; Catalysis; Copper; Gallium; Hydrogen-Ion Concentration; Keto Acids; Methanol; Picolines; Pyridoxal Phosphate; Serine; Sulfates; Threonine | 1968 |
Carbohydrate formation from various precursors in noenatal rat liver.
Topics: Alanine; Animals; Animals, Newborn; Carbon Isotopes; Caseins; Gluconeogenesis; Glucose; Glycerol; Glycogen; Hydro-Lyases; In Vitro Techniques; Lactates; Liver; Oxaloacetates; Rats; Serine; Threonine | 1968 |
Role of streptomycin in the life of Streptomyces griseus: streptidine-containing fractions in the cell walls of Streptomyces griseus strains.
Topics: Alanine; Arginine; Cell Wall; Chromatography, Ion Exchange; Chromatography, Paper; Guanidines; Hydrogen-Ion Concentration; Infrared Rays; Methods; Serine; Spectrum Analysis; Streptomyces; Streptomycin; Threonine | 1968 |
The biosynthesis of L-threonine ethanolamine phosphate in fish.
Topics: Amino Alcohols; Animals; Autoradiography; Calcium; Cyprinidae; Digestive System; Electrophoresis; Esters; Kidney; Liver; Magnesium; Manganese; Phosphates; Phospholipids; Phosphorus Isotopes; Salmonidae; Serine; Threonine; Time Factors | 1968 |
Amino acid binding to luteinizing hormone.
Topics: Acetates; Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Cellulose; Chromatography, Gel; Countercurrent Distribution; Electrophoresis; Glycine; Glycoproteins; Guanidines; Luteinizing Hormone; Peptides; Protein Binding; Serine; Sheep; Threonine | 1968 |
Side reactions in the synthesis of peptides containing the aspartyglycyl sequence.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Glycine; Heterocyclic Compounds; Histidine; Imides; Peptides; Phenylalanine; Serine; Succinates; Threonine | 1968 |
The formation of O-sulphates of serine and threonine in protein hydrolysates.
Topics: Autoradiography; Chemical Phenomena; Chemistry; Esters; Histones; Iontophoresis; Protein Hydrolysates; Serine; Sulfates; Threonine | 1968 |
[The formation of the neutral carbohydrates in the horny layer].
Topics: Amino Acids; Carbohydrates; Glucose; Granulation Tissue; Humans; Lactose; Ornithine; Serine; Skin; Threonine | 1968 |
Autodigestion of the main proteolytically active component of the stem bromelain.
Topics: Alanine; Arginine; Bromelains; Chromatography; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1968 |
[Incorporation of 14C-proline into ripening wheat].
Topics: Asparagine; Carbon Isotopes; Chromatography, Thin Layer; Glycine; Peptides; Plant Proteins; Proline; Serine; Threonine; Triticum | 1968 |
Amino acids involved in chromophore-protein linkages in phycoerythrins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Pigments, Biological; Proteins; Serine; Threonine | 1968 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Histidine; Histocytochemistry; Humans; Isoleucine; Leucine; Lysine; Methods; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1968 |
[Isolation and identification of a ninhydrin-positive complex from the brain under the effect of gamma-amino butyric acid].
Topics: Amino Acids; Aminobutyrates; Animals; Brain Chemistry; Carotid Arteries; Dogs; Drug Stability; Glycine; Indicators and Reagents; Injections, Intra-Arterial; Serine; Stimulation, Chemical; Threonine; Time Factors; Tyrosine | 1968 |
Number of polypeptide components in bacteriophage T2L contractile sheaths.
Topics: Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Coliphages; Glutamine; Glycine; Hydrazines; Leucine; Peptides; Serine; Threonine; Tryptophan; Valine | 1968 |
[Crystalline leucine aminopeptidase from bovine lens. Amino acid composition and N-terminal amino acids, II].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography; Formates; Glutamates; Glutamine; Glycine; Lens, Crystalline; Leucine; Leucyl Aminopeptidase; Lysine; Serine; Threonine | 1968 |
Studies of action of acids and bases on porcine submaxillary mucin.
Topics: Amino Acids; Animals; Antigens; Carbohydrates; Chemical Phenomena; Chemistry; Electrophoresis; Endopeptidases; Female; Hydrogen-Ion Concentration; Immune Sera; Indicators and Reagents; Male; Mucins; Neuraminic Acids; Precipitin Tests; Protein Hydrolysates; Rabbits; Serine; Submandibular Gland; Swine; Threonine | 1969 |
Nuclear phosphoproteins. I. Isolation and characterization of a phosphoprotein fraction from calf thymus nuclei.
Topics: Adenosine Triphosphate; Animals; Cattle; Cell Nucleus; Cobalt; Electrophoresis; Iron; Kinetics; Magnesium; Manganese; Nucleoproteins; Nucleotides; Oxidative Phosphorylation; Phosphates; Phosphorus Isotopes; Phosphotransferases; Serine; Spectrum Analysis; Threonine; Thymus Gland; Ultraviolet Rays | 1969 |
Determination of dinitrophenylamino acids in structural proteins by chromatography on nylon powder columns. II. The ether-soluble dinitrophenylamino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Hydrogen-Ion Concentration; Methods; Nylons; Proteins; Serine; Threonine; Valine | 1969 |
Effects of feedback modifiers on mutationally altered threonine deaminases of Rhodopseudomonas spheroides.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Feedback; Hydro-Lyases; Isoleucine; Kinetics; Molecular Biology; Mutation; Rhodopseudomonas; Serine; Threonine; Valine | 1969 |
Studies on the structure and function of muscle aldolase. IV. The action of dilute alkali on primary structure and its effect on the determination of subunit molecular weight.
Topics: Aldehyde-Lyases; Alkalies; Animals; Boron Compounds; Buffers; Carboxypeptidases; Chemical Phenomena; Chemistry; Computers; Electrophoresis; Electrophoresis, Disc; Glycine; Hexosephosphates; Hydrogen-Ion Concentration; Molecular Weight; Muscles; Peptides; Proline; Rabbits; Serine; Solubility; Succinates; Temperature; Threonine; Time Factors; Ultracentrifugation | 1969 |
[Phosphoproteins of plasma membranes isolated from rat liver. Incorporation of 32P into phosphoproteins].
Topics: Adenosine Triphosphate; Animals; Cytoplasm; Densitometry; Drug Stability; Electrophoresis; Histidine; Hydrogen-Ion Concentration; Liver; Male; Membranes; Microsomes; Mitochondria, Liver; Phosphates; Phosphorus; Phosphorus Isotopes; Potassium; Protein Biosynthesis; Rats; Serine; Sodium; Threonine; Time Factors | 1969 |
Effect of glucagon on concentration of several free amino acids in plasma.
Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine | 1969 |
An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: application to catalase.
Topics: Amino Acids; Bromine; Catalase; Countercurrent Distribution; Cyanides; Fluoroacetates; Formates; Kinetics; Methionine; Methods; Serine; Threonine | 1969 |
Gas-liquid chromatography of radioactive amino acids as their trifluoroacetyl ester derivatives.
Topics: Amino Acids; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gas; Esters; Glutamates; Glycine; Hydroxyproline; Isoleucine; Leucine; Methods; Phenylalanine; Serine; Threonine | 1969 |
Effect of prior high protein intake, serine dehydratase activity and plasma amino acids of rats fed amino acid-imbalanced diets.
Topics: Adaptation, Physiological; Amino Acids; Animals; Caseins; Diet; Dietary Proteins; Growth; Histidine; Hydro-Lyases; L-Serine Dehydratase; Liver; Male; Rats; Serine; Threonine; Time Factors | 1969 |
Plasma and urinary amino acids in primary gout, with special reference to glutamine.
Topics: Adolescent; Adult; Aged; Amino Acids; Ammonia; Autoanalysis; Chromatography; Dietary Proteins; Glutamine; Gout; Humans; Kidney; Kidney Tubules; Leucine; Male; Middle Aged; Renal Aminoacidurias; Serine; Threonine | 1969 |
Circadian periodicity of blood amino acids in normal and adrenalectomized mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Circadian Rhythm; Cystine; Densitometry; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Mice; Serine; Threonine; Tryptophan; Tryptophan Oxygenase; Tyrosine; Valine | 1969 |
Taxonomic comparison of the amino termini of microbial cell proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteria; Bacterial Proteins; Biological Evolution; Eukaryota; Fungi; Methionine; Proteins; Serine; Threonine | 1969 |
The N1-methylguanosine content of hamster liver tRNA.
Topics: Animals; Carbon Isotopes; Chromatography, Ion Exchange; Cricetinae; Hydrogen-Ion Concentration; Liver; Mice; Nucleosides; Rabbits; Rats; RNA, Transfer; Serine; Spectrophotometry; Threonine; Ultracentrifugation | 1969 |
Encephalopathy in combination with a new pattern of aminoaciduria.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases; Central Nervous System; Chromatography; Cyanosis; Dyspnea, Paroxysmal; Electroencephalography; Exchange Transfusion, Whole Blood; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Infant, Premature, Diseases; Male; Serine; Spectrophotometry; Threonine | 1969 |
Properties of L-serine dehydratase purified from rat liver after induction by fasting or feeding casein hydrolysate.
Topics: Adrenalectomy; Animals; Binding Sites; Caseins; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography, Gel; Enzyme Induction; Fasting; Hydro-Lyases; Hydrocortisone; L-Serine Dehydratase; Liver; Protein Hydrolysates; Rats; Serine; Stereoisomerism; Threonine | 1969 |
[Preliminary results of a drug therapy of a group of school-age mental retardates].
Topics: Adolescent; Amino Acids; Arginine; Child; Female; Glutamine; Humans; Intellectual Disability; Male; Serine; Threonine; Tryptophan; Vitamin B 12 | 1969 |
Synthesis of the antibiotic nisin: formation of lanthionine and beta-methyl-lanthionine.
Topics: Amino Acids; Anti-Bacterial Agents; Carbon Isotopes; Cysteine; Electrophoresis; Serine; Streptococcus; Sulfides; Sulfur Isotopes; Threonine; Tritium | 1969 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Muscular Dystrophies; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1969 |
Comparative chemistry of collagen.
Topics: Amino Acids; Animals; Biological Evolution; Cattle; Chickens; Collagen; Fishes; Imines; Mammals; Serine; Species Specificity; Threonine | 1969 |
[Study of blood group A substances isolated from bronchial mucus].
Topics: ABO Blood-Group System; Aspartic Acid; Blood Group Antigens; Bronchi; Bronchial Neoplasms; Bronchitis; Chromatography, Gel; Chromatography, Thin Layer; Galactose; Glucosamine; Glutamates; Hexosamines; Humans; Hydrogen-Ion Concentration; Molecular Weight; Mucus; Polysaccharides; Serine; Threonine | 1969 |
Nephrotoxic action of D-serine determined by renal enzyme excretion in rats.
Topics: Alkaline Phosphatase; Aminobutyrates; Animals; Diuresis; Kidney; L-Lactate Dehydrogenase; Male; Rats; Serine; Stereoisomerism; Succinate Dehydrogenase; Threonine | 1969 |
Amino acid composition of beta-caseins from the milks of Bos indicus and Bos taurus cows: a comparative study.
Topics: Acrylates; Alanine; Amino Acids; Animals; Arginine; Autoanalysis; Caseins; Cattle; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis; Gels; Glutamates; Histidine; Lysine; Milk; Peptides; Phosphorus; Serine; Species Specificity; Threonine; Trypsin; Tryptophan | 1969 |
[Studies on the amino acid composition of some African legumes].
Topics: Amino Acids; Arginine; Aspartic Acid; Canavanine; Chromatography; Cystine; Food Analysis; Glutamine; Glycine; Histidine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants, Edible; Proline; Proteins; Serine; Threonine; Tryptophan; Tyrosine; Valine; Vegetables | 1969 |
Structure of Mn2+ and Cu2+ complexes with L-methionine, S-methyl-L-cysteine, L-threonine and L-serine.
Topics: Alanine; Amino Acids; Aminobutyrates; Binding Sites; Chemical Phenomena; Chemistry; Copper; Cysteine; Drug Stability; Keto Acids; Magnetic Resonance Spectroscopy; Manganese; Methionine; Serine; Sulfur; Threonine | 1969 |
Amino acid analysis of glycine-extracted deoxyribonucleoproteins (sea urchin sperm).
Topics: Amino Acids; Animals; Arginine; DNA; Echinodermata; Electrophoresis; Glycine; Lysine; Male; Nucleoproteins; Nucleotides; Purines; Pyrimidines; Serine; Spermatozoa; Threonine; Valine | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Isolation of a glycopeptide from a 7S protein in soybean globulins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Globulins; Glucosamine; Glutamates; Glycine; Glycine max; Glycoproteins; Mannose; Molecular Weight; Monosaccharides; Polysaccharides; Serine; Threonine | 1969 |
The glycoprotein structure of yeast invertase.
Topics: Amino Acids; Asparagine; Carbohydrates; Cell Wall; Chemical Phenomena; Chemistry; Chromatography, Gel; Dextrans; Glucosamine; Glycoproteins; Glycoside Hydrolases; Hydrazines; Hydrogen-Ion Concentration; Oligosaccharides; Peptide Hydrolases; Peptides; Polysaccharides; Saccharomyces; Serine; Streptomyces; Sucrase; Threonine | 1969 |
Dissociation-produced loss of regulatory control of homoserine dehydrogenase of Rhodospirillum rubrum. II. Some properties of the regulatable and nonregulatable forms.
Topics: Alcohol Oxidoreductases; Amino Acids; Binding Sites; Buffers; Chemical Phenomena; Chemistry; Feedback; Kinetics; Mercury; Osmolar Concentration; Rhodospirillum; Serine; Threonine | 1969 |
Effect of source of dietary nitrogen on plasma concentration and urinary excretion of amino acids of men.
Topics: Adult; Amino Acids; Arginine; Caseins; Citrates; Diet; Fasting; Glutamates; Glycine; Histidine; Humans; Male; Nitrogen; Proline; Quaternary Ammonium Compounds; Serine; Taurine; Threonine; Time Factors | 1969 |
[On a carbohydrate-protein bond in beta-fructofuranosidase].
Topics: Chromatography, Gas; Glycoproteins; Glycoside Hydrolases; Mannose; Protein Binding; Serine; Sodium Hydroxide; Sucrase; Threonine | 1969 |
Desulfation of L-serine-O-sulfate and L-threonine-O-sulfate by human plasma.
Topics: Enzymes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Serine; Sulfates; Threonine | 1965 |
A method for the determination of free plasma amino acids in ultra-micro quantities.
Topics: Alanine; Amino Acids; Blood Chemical Analysis; Electrophoresis; Histidine; Humans; In Vitro Techniques; Leucine; Microchemistry; Ornithine; Radiotherapy; Serine; Threonine; Urine; Valine | 1965 |
Studies on glycoproteins. XII. About glycosidic-ester linkages in submaxillary gland glycoproteins prepared from sheep.
Topics: Animals; Borates; Chemical Phenomena; Chemistry; Chromatography, Paper; Glycoproteins; Glycosides; Hexosamines; In Vitro Techniques; Lithium; Peptide Hydrolases; Serine; Sheep; Submandibular Gland; Threonine | 1965 |
Immunochemical studies on blood groups. XXXIII. The effects. of alkaline borohydride and of alkali on blood group A, B, and H substances.
Topics: ABO Blood-Group System; Aminobutyrates; Arginine; Blood Group Antigens; Borates; Chemical Phenomena; Chemistry; Galactose; Hexosamines; Histidine; Humans; In Vitro Techniques; Mucins; Serine; Sodium Hydroxide; Threonine | 1965 |
Stimulation of the binding of aminoacyl-sRNA to ribosomes by tubercidin (7-deazaadenosine) and N 6-dimethyladenosine containing trinucleoside diphosphate analogs.
Topics: Alanine; Anti-Bacterial Agents; Glutamates; Glycine; In Vitro Techniques; Lysine; Nucleotides; Proline; Ribosomes; RNA, Transfer; Serine; Threonine | 1965 |
[Velocity of the imidazole catalysis of o-acetylation of derivatives and peptides of serines and threonines].
Topics: Chemical Phenomena; Chemistry; Imidazoles; Serine; Threonine | 1965 |
The complete enzymic degradation of glycopeptides containing O-seryl and O-threonyl linked carbohydrate.
Topics: Animals; Cattle; Glycoproteins; Glycoside Hydrolases; In Vitro Techniques; Peptides; Serine; Sheep; Spleen; Submandibular Gland; Threonine | 1964 |
Serine and threonine glycosidic linkages in bovine submaxillary mucin.
Topics: Amino Acids; Animals; Borates; Cattle; Chemical Phenomena; Chemistry; Dialysis; Glycosides; In Vitro Techniques; Mucins; Serine; Submandibular Gland; Threonine | 1964 |
[Studies on serine dehydratase reaction in yeast].
Topics: Chromatography, Gel; Chromatography, Ion Exchange; Enzymes; Hydro-Lyases; Kinetics; Leucine; Pyridoxal Phosphate; Saccharomyces; Serine; Threonine | 1965 |
[The complete chemical synthesis of L-C14-serine-ethanolamine and L-C14 threonine-ethanolamine phosphodiesters].
Topics: Amino Alcohols; Carbon Isotopes; Chemistry, Organic; Organic Chemistry Phenomena; Phosphates; Serine; Threonine | 1964 |
[Biological significance and metabolic aspects of L-serine-ethanolamine and L-threonine-ethanolamine phosphodiesters].
Topics: Amino Alcohols; Amphibians; Animals; Central Nervous System; Eels; Fishes; Intestinal Mucosa; Myocardium; Phosphates; Reptiles; Serine; Threonine | 1964 |
[Preliminary data on the organic synthesis of L-serine-ethanolamine ad L-threonine-ethanolamine phosphodiesters labeled with C-14].
Topics: Amino Alcohols; Carbon Isotopes; Chemistry, Organic; Organic Chemistry Phenomena; Phosphates; Phosphatidylethanolamines; Serine; Threonine | 1964 |
The determination of amino acids in 0.1 ml. of blood plasma.
Topics: Alanine; Amino Acids; Arginine; Blood Chemical Analysis; Chemistry, Clinical; Chromatography, Gel; Chromatography, Paper; Colorimetry; Densitometry; Glutamine; Glycine; Humans; In Vitro Techniques; Lysine; Microchemistry; Serine; Taurine; Threonine; Valine | 1966 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Inhibition of bovine growth hormone activity by acetyl proteins.
Topics: Acetates; Albumins; Animals; Antimetabolites; Body Weight; Caseins; Cattle; Growth Hormone; Hypophysectomy; Proline; Rats; Serine; Serum Albumin, Bovine; Threonine; Thyrotropin | 1966 |
Effect of amino acids on the nitrogenase system of Klebsiella pneumoniae.
Topics: Amino Acids; Aspartic Acid; Autoanalysis; Enzyme Induction; Glutamates; Histidine; Isoleucine; Klebsiella; Leucine; Nitrogen; Oxidoreductases; Quaternary Ammonium Compounds; Serine; Threonine | 1966 |
Threonine deaminase of Clostridium tetanomorphum. I. Purification and properties.
Topics: Adenine Nucleotides; Catalysis; Chemical Phenomena; Chemistry; Clostridium; Enzymes; Hot Temperature; Hydro-Lyases; Kinetics; Serine; Threonine | 1966 |
Synthesis of phosphopeptides. V. Further dipeptides, tripeptides and O-phosphorylated derivatives of L-serine.
Topics: Chemical Phenomena; Chemistry; Dipeptides; Phosphopeptides; Serine; Threonine | 1966 |
Isolation of amino acyl oligonucleotides from T-1 ribonuclease digests of soluble ribonucleic acid charged with serine, glycine, threonine, and alanine.
Topics: Alanine; Chromatography, Ion Exchange; Electrophoresis; Glycine; Nucleotides; Ribonucleases; RNA, Transfer; Saccharomyces; Serine; Threonine | 1966 |
O-ring joint tubes for protein hydrolyzates.
Topics: Biochemistry; Protein Hydrolysates; Serine; Threonine | 1966 |
Polyamide layer chromatography of DNP-amino acids.
Topics: Alanine; Amides; Arginine; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
Amino acid transport in the goldfish intestine.
Topics: Alanine; Animals; Biological Transport, Active; Fishes; Histidine; Intestinal Mucosa; Leucine; Methionine; Phenylalanine; Serine; Threonine; Valine | 1966 |
A study of the correlation between the amino acid composition and the helical content of proteins.
Topics: Protein Biosynthesis; Proteins; Serine; Statistics as Topic; Threonine | 1966 |
Radiochemical degradation of threonine and serine.
Topics: Aspartic Acid; Carbon Isotopes; Chromatography, Paper; Cobalt Isotopes; Nitrogen; Oxygen; Radiochemistry; Serine; Threonine | 1966 |
Gas chromatographic separation of DNP amino acids and its application to the analysis of serum amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Cholesterol; Chromatography, Gas; Glutamates; Glycine; Hydroxyproline; Indicators and Reagents; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Valine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
[Composition of the amino acid pool of Neurospora in deficiency of growth substance].
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Biotin; Choline; Chromatography, Ion Exchange; Culture Media; Glutamates; Glycine; Growth Inhibitors; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Pyridoxine; Riboflavin; Serine; Threonine; Tyrosine; Valine | 1966 |
[In vitro metabolism of adipose tissue. II. Metabolism of L-lysine, L-threonine, L-serine and glycine in epididymal adipose tissue of the normal rat].
Topics: Adipose Tissue; Animals; Autoanalysis; Biological Transport, Active; Carbon Dioxide; Culture Techniques; Epididymis; Glucose; Glycine; Insulin; Lipid Metabolism; Lysine; Male; Proteins; Rats; Serine; Stimulation, Chemical; Threonine | 1966 |
[On the structure of protamine. VII. On the effect of the age of the fishes on the composition of their protamine].
Topics: Age Factors; Alanine; Amino Acids; Animals; Arginine; Fishes; Glutamates; Proline; Protamines; Serine; Threonine; Tyrosine; Valine | 1966 |
[Quantitative changes in amino acids in grapes at different ripening stages].
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Chromatography, Ion Exchange; Fruit; Glutamates; Serine; Threonine; Valine | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
Pteridine biosynthesis in the butterfly Colias eurytheme.
Topics: Animals; Chromatography, Paper; Hydroxybutyrates; Insecta; Lactates; Malates; Nucleosides; Pteridines; Pyruvates; Serine; Threonine | 1967 |
Renal metabolism of alanine.
Topics: Alanine; Ammonia; Animals; Dogs; Glomerular Filtration Rate; Glutamates; Glutamine; Glycine; Ketoglutaric Acids; Kidney; Kidney Tubules; Oxidation-Reduction; Pyruvates; Serine; Threonine | 1967 |
Free amino acids in gamma-irradiated carrots.
Topics: Acetates; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Carbon Isotopes; Glutamates; Leucine; Methionine; Plants, Edible; Proline; Radiation Effects; Serine; Threonine; Tyrosine | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Comparison of the carbohydrate and amino acid composition of bovine, ovine and human luteinizing hormone.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cattle; Galactose; Glucosamine; Glutamates; Hexosamines; Hexoses; Humans; In Vitro Techniques; Luteinizing Hormone; Lysine; Mannose; Neuraminic Acids; Proline; Serine; Sheep; Threonine; Valine | 1967 |
A new developing solvent for paper chromatography of various phenolic compounds, sugars and amino acids.
Topics: Amino Acids; Anthocyanins; Arginine; Asparagine; Carbohydrates; Chromatography, Paper; Gallic Acid; Glutamates; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Phenols; Phenylalanine; Phloroglucinol; Proline; Resorcinols; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Effects of cortisol and 19-nortestosterone on the free amino acid pools and amino acid uptake of cultured cells.
Topics: Alanine; Amino Acids; Aspartic Acid; Biological Transport; Carbon Isotopes; Culture Techniques; Glycine; HeLa Cells; Hydrocortisone; Nandrolone; Neoplasms, Experimental; Serine; Threonine | 1967 |
Correlation between serine and thermal stability of collagen.
Topics: Animals; Annelida; Ascaris; Cattle; Collagen; Fishes; Hot Temperature; Humans; Hydroxyproline; Proline; Rats; Serine; Snails; Threonine; Tyrosine | 1967 |
The effect of sodium on the fermentation of glutamic acid by Peptococcus aerogenes.
Topics: Carbon Isotopes; Fermentation; Glutamates; Histidine; Peptococcus; Serine; Sodium; Threonine | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
Synthesis of homocysteine and cysteine by enzyme extracts of spinach.
Topics: Amino Acids; Chromatography, Paper; Cysteine; Electrophoresis; Homocysteine; In Vitro Techniques; Methionine; Plant Extracts; Plants, Edible; Serine; Sulfides; Sulfur Isotopes; Threonine; Vegetables | 1967 |
Urinary amino acids of rats receiving high sugar diets.
Topics: Alanine; Alcohols; Amino Acids; Animals; Arabinose; Ascorbic Acid; Asparagine; Aspartic Acid; Dietary Carbohydrates; Female; Galactose; Glucose; Glutamates; Glycine; Inositol; Intestines; Neomycin; Rats; Ribose; Serine; Taurine; Threonine; Xylitol; Xylose | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Concentrations of free glucogenic amino acids in livers of rats subjected to various metabolic stresses.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; Gluconeogenesis; Glutamates; Glutamine; Hypoxia; Insulin; Liver; Male; Phlorhizin; Rats; Serine; Starvation; Threonine; Transaminases | 1967 |
Structural basis of kanamycin for miscoding activity.
Topics: Adenine Nucleotides; Amines; Amino Acids; Amino Sugars; Arginine; Chemical Phenomena; Chemistry; Cytosine Nucleotides; DNA; Genetic Code; Isoleucine; Kanamycin; Leucine; Lysine; Phenylalanine; Polynucleotides; Proline; Serine; Threonine; Uracil Nucleotides; Valine | 1967 |
Gluconeogenesis from amino acids in neonatal rat liver.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartate Aminotransferases; Aspartic Acid; Gluconeogenesis; Glutamates; Glycine; Histidine; In Vitro Techniques; Leucine; Liver; Liver Glycogen; Phenylalanine; Proline; Rats; Serine; Spectrophotometry; Threonine; Tyrosine; Valine | 1967 |
Studies on glycopeptides released by trypsin from intact human erythrocytes.
Topics: Amino Acids; Cellulose; Centrifugation, Zonal; Chromatography; Chromatography, Gel; Erythrocytes; Galactose; Glucosamine; Glycosides; Hexosamines; Humans; Neuraminic Acids; Oligosaccharides; Peptides; Serine; Threonine; Tritium; Trypsin | 1967 |
Selective fragmentation of threonyl and seryl dipeptides.
Topics: Amino Acids; Autoanalysis; Hydroxylamines; Oxidation-Reduction; Peptides; Phenylhydrazines; Serine; Threonine | 1967 |
The influence of nitrogenous compounds on growth of Pythium species.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Cysteine; Fungi; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitrogen; Peptones; Quaternary Ammonium Compounds; Serine; Succinates; Threonine; Yeast, Dried | 1967 |
Lack of specificity of isoleucyl-tRNA synthetase: evidence for anomalous charging of tRNA.
Topics: Bacillus; Carbon Isotopes; Catalysis; Chromatography; Isoleucine; Ligases; RNA, Bacterial; RNA, Transfer; Serine; Temperature; Threonine; Valine | 1967 |
Action of sheep liver threonine dehydratase on L-allothreonine and copper salts of L-threonine and L-serine.
Topics: Animals; Catalysis; Chelating Agents; Chemical Phenomena; Chemistry, Physical; Copper; Hydro-Lyases; Isoleucine; Kinetics; Liver; Serine; Sheep; Spectrophotometry; Temperature; Threonine | 1967 |
The stability constants of metal complexes of serine and threonine.
Topics: Chemical Phenomena; Chemistry, Physical; Cobalt; Computers; Copper; Drug Stability; Hydrogen-Ion Concentration; Lead; Manganese; Nickel; Organometallic Compounds; Potentiometry; Serine; Threonine; Zinc | 1967 |
Effect of amino acids on zinc-65 incorporation by Ehrlich ascites tumor cells in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Lysine; Methionine; Mice; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Zinc; Zinc Isotopes | 1967 |
Activation of brain calcineurin towards proteins containing Thr(P) and Ser(P) by Ca2+, calmodulin, Mg2+ and transition metal ions.
Topics: Animals; Brain; Calcium; Calmodulin; Calmodulin-Binding Proteins; Caseins; Cattle; Cobalt; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Nickel; Phosphoprotein Phosphatases; Phosphoproteins; Phosphoserine; Phosphothreonine; Serine; Threonine | 1984 |
Oligosaccharide branching of glycoproteins: biosynthetic mechanisms and possible biological functions.
Topics: Animals; Asparagine; Carbohydrate Sequence; Glycoproteins; Hexosyltransferases; Mucins; Oligosaccharides; Protein Processing, Post-Translational; Serine; Swine; Threonine | 1982 |
Synthesis and possible role of carbohydrate moieties of yeast glycoproteins.
Topics: Asparagine; Biological Transport; Dolichol Phosphates; Endoplasmic Reticulum; Fungal Proteins; Glycoproteins; Liposomes; Mannose; Oligosaccharides; Polyisoprenyl Phosphates; Serine; Threonine | 1982 |
Intermediary metabolism in Legionella pneumophila: utilization of amino acids and other compounds as energy sources.
Topics: Acetates; Amino Acids; Carboxylic Acids; Glucose; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Legionella; Oxygen Consumption; Pentosephosphates; Pyruvates; Pyruvic Acid; Serine; Threonine | 1983 |
Study of the relationship between free amino acids and cataract in human lenses.
Topics: Adult; Aged; Alanine; Amino Acids; Cataract; Glutamates; Glutamic Acid; Glycine; Humans; Lens, Crystalline; Leucine; Middle Aged; Serine; Threonine | 1984 |
Symmetrical distribution of amino acid neurotransmitters in the right and left cerebral cortex of the rat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Threonine; Tissue Distribution | 1984 |
Silver staining of phosphoserine and phosphothreonine in nucleolar and other phosphoproteins.
Topics: Animals; Cell Nucleolus; Histocytochemistry; Liver Neoplasms, Experimental; Phosphoserine; Phosphothreonine; Rats; Serine; Silver; Staining and Labeling; Threonine | 1981 |
Separation of phosphohydroxyamino acids by high-performance liquid chromatography.
Topics: Animals; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic AMP; Hydrolysis; Myelin Basic Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Serine; Threonine; Tyrosine | 1982 |
Two-dimensional separation of phosphoamino acids from nucleoside monophosphates.
Topics: Adenosine Monophosphate; Chromatography, Thin Layer; Cytidine Monophosphate; Electrophoresis; Escherichia coli; Guanosine Monophosphate; Nucleotides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Thymidine Monophosphate; Tyrosine; Uracil Nucleotides; Uridine Monophosphate | 1982 |
Dansylation and high-performance liquid chromatographic separation of phosphoserine, phosphothreonine and phosphotyrosine from 32P-labeled protein hydrolyzates.
Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Dansyl Compounds; Hydrolysis; In Vitro Techniques; Isotope Labeling; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Rats; Serine; Threonine; Tyrosine | 1982 |
A rapid microdetermination of phosphoserine, phosphothreonine, and phosphotyrosine in proteins by automatic cation exchange on a conventional amino acid analyzer.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrolysis; Myocardium; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1983 |
Polyamide thin-layer chromatography of phosphorylated tyrosine, threonine, and serine.
Topics: Chromatography, Thin Layer; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1983 |
Phosphorylation of tyrosine in cultured human placenta.
Topics: Culture Techniques; Female; Gestational Age; Humans; Phosphoproteins; Phosphorylation; Phosphotyrosine; Placenta; Pregnancy; Protein Kinases; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1984 |
Chemical properties, isolation, and analysis of O-phosphates in proteins.
Topics: Carbon Radioisotopes; Chemical Phenomena; Chemistry; Hydrolysis; Indicators and Reagents; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tritium; Tyrosine | 1984 |
The structural polypeptides of aphthovirus are phosphoproteins.
Topics: Aphthovirus; Isoelectric Point; Phosphoproteins; Serine; Threonine; Viral Proteins | 1980 |
Phosphorylation pattern of large T antigens in mouse cells infected by simian virus 40 wild type or deletion mutants.
Topics: Animals; Antigens, Viral; Antigens, Viral, Tumor; Cells, Cultured; Kidney; Mice; Mutation; Phosphorylation; Phosphoserine; Phosphothreonine; Serine; Simian virus 40; Threonine; Trypsin | 1982 |
Metabolic turnover of phosphorylation sites in simian virus 40 large T antigen.
Topics: Antigens, Viral; Antigens, Viral, Tumor; Half-Life; Mutation; Phosphorylation; Phosphoserine; Phosphothreonine; Serine; Simian virus 40; Temperature; Threonine | 1983 |
Control of hepatic utilization of serine, glycine and threonine in fed and starved rats.
Topics: Alanine; Alanine Transaminase; Animals; Dietary Carbohydrates; Dietary Proteins; Gluconeogenesis; Glycine; L-Serine Dehydratase; Lactates; Lactic Acid; Liver; Male; Rats; Serine; Starvation; Threonine | 1983 |
The B4 lectin from Vicia villosa seeds interacts with N-acetylgalactosamine residues alpha-linked to serine or threonine residues in cell surface glycoproteins.
Topics: Acetylgalactosamine; Animals; Cell Line; Erythrocytes; Galactosamine; Glycoproteins; Humans; Lectins; Lymphoma; Mice; Plant Lectins; Seeds; Serine; Surface Properties; Threonine | 1983 |
The carbohydrate moiety of human platelet glycocalicin.
Topics: Blood Platelets; Carbohydrate Conformation; Carbohydrates; Chromatography; Glycoproteins; Glycoside Hydrolases; Humans; Membrane Proteins; Methylation; Molecular Weight; Oligosaccharides; Platelet Glycoprotein GPIb-IX Complex; Serine; Threonine | 1983 |
Characterization of the catalytic pathway for D-serine dehydratase. Evidence for variation of the rate-determining step with substrate structure.
Topics: Escherichia coli; Hydrogen-Ion Concentration; Isomerism; Kinetics; L-Serine Dehydratase; Magnetic Resonance Spectroscopy; Mathematics; Serine; Substrate Specificity; Threonine | 1983 |
Isolation and characterization of human cervical-mucus glycoproteins.
Topics: Amino Acids; Carbohydrates; Centrifugation, Density Gradient; Cervix Mucus; Chemical Phenomena; Chemistry; Chromatography, Gel; Female; Humans; Molecular Weight; Mucins; Pregnancy; Scattering, Radiation; Serine; Threonine | 1983 |
Biochemical studies of olfaction: binding specificity of odorants to a cilia preparation from rainbow trout olfactory rosettes.
Topics: Alanine; Animals; Binding, Competitive; Central Nervous System; Cilia; Kinetics; Odorants; Olfactory Pathways; Sensory Receptor Cells; Serine; Smell; Threonine; Tritium; Trout | 1983 |
Substrate recognition by oligosaccharyltransferase. Studies on glycosylation of modified Asn-X-Thr/Ser tripeptides.
Topics: Animals; Asparagine; Chickens; Female; Glycopeptides; Hexosyltransferases; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Membrane Proteins; Microsomes; Oligopeptides; Oviducts; Serine; Substrate Specificity; Threonine; Transferases | 1983 |
Specific method for the fragmentation of the polypeptide chain of glycoproteins. Distribution of carbohydrate chains on the peptide core of blood-group-specific glycoprotein.
Topics: Amino Acids; Blood Group Antigens; Carbohydrates; Chromatography, Gel; Glycoproteins; Humans; Peptide Fragments; Peptides; Serine; Threonine | 1983 |
Synthetic TN glycopeptide related to human glycophorin AM. High-field proton and carbon-13 nuclear magnetic resonance study.
Topics: Blood Group Antigens; Carbohydrate Sequence; Glycopeptides; Glycophorins; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Serine; Sialoglycoproteins; Threonine | 1983 |
Some properties of synthetic fucopyranosylserines and -threonines.
Topics: alpha-L-Fucosidase; Fucose; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Serine; Spectrophotometry, Infrared; Stereoisomerism; Threonine | 1983 |
O-glycosidic linkage in glycoprotein isolates from human ocular mucus.
Topics: Acetylgalactosamine; Chemical Phenomena; Chemistry; Eye; Glycoproteins; Humans; Mucins; Mucus; Serine; Sialic Acids; Threonine | 1983 |
Human duodenal gland (Brunner's gland) mucus glycoprotein analysis.
Topics: Amino Acids; Animals; Brunner Glands; Carbohydrates; Centrifugation, Density Gradient; Chromatography, Gel; Cysteine; Duodenum; Glycoproteins; Humans; Mucus; Rats; Serine; Threonine | 1984 |
Radioautographic visualization and biochemical identification of O-phosphoserine- and O-phosphothreonine-containing phosphoproteins in mineralizing embryonic chick bone.
Topics: Animals; Bone Development; Bone Matrix; Chick Embryo; Osteoblasts; Phosphoproteins; Serine; Threonine | 1984 |
Synthesis of dinitrophenyl derivatives of 3-O-fatty acyl esters of serine and threonine.
Topics: Animals; Chromatography, Thin Layer; Dinitrophenols; Indicators and Reagents; Magnetic Resonance Spectroscopy; Oleic Acids; Palmitic Acids; Serine; Threonine | 1984 |
Effects of replacing serine and threonine residues within the signal peptide on the secretion of the major outer membrane lipoprotein of Escherichia coli.
Topics: Bacterial Outer Membrane Proteins; Base Sequence; Cell Membrane; Escherichia coli; Genes; Genes, Bacterial; Membrane Proteins; Mutation; Peptides; Plasmids; Protein Sorting Signals; Serine; Threonine | 1984 |
Intrahelical hydrogen bonding of serine, threonine and cysteine residues within alpha-helices and its relevance to membrane-bound proteins.
Topics: Cysteine; Hydrogen Bonding; Membrane Proteins; Protein Conformation; Serine; Threonine | 1984 |
Model studies on N-glycosylation of proteins.
Topics: Amino Acid Sequence; Animals; Asparagine; Carbohydrate Metabolism; Hydrogen; Models, Chemical; Proteins; Serine; Threonine | 1984 |
Characterization of endogenous phosphorylation in isolated cardiac sarcolemma.
Topics: Animals; Chromatography, Gel; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; In Vitro Techniques; Lipid Metabolism; Magnesium; Membranes; Myocardium; Phosphates; Phosphorylation; Sarcolemma; Serine; Swine; Threonine | 1983 |
Glycogen synthase in rat adipocytes and skeletal muscle is phosphorylated on both serine and threonine.
Topics: Adipose Tissue; Animals; Chromatography, Thin Layer; Glycogen Synthase; Macromolecular Substances; Male; Muscles; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Rats; Serine; Threonine | 1984 |
Neutral amino acid transport and in vitro aging.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Cell Line; Cell Survival; Culture Media; Fibroblasts; Humans; Kinetics; Phenylalanine; Serine; Threonine | 1984 |
Amino acid requirements of Legionella pneumophila.
Topics: Amino Acids; Bacteria; Culture Media; Humans; Legionnaires' Disease; Methionine; Serine; Threonine | 1980 |
Plasma amino acids in 3/sec spike-wave epilepsy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aspartic Acid; Child; Child, Preschool; Epilepsy; Female; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Middle Aged; Phenylalanine; Serine; Taurine; Threonine; Tyrosine; Valine | 1980 |
Evidence against the participation of lipid intermediates in the in vitro biosynthesis of serine(threonine)-N-acetyl-D-galactosamine linkages in submaxillary mucin.
Topics: Acetylgalactosamine; Animals; Cattle; Cell Membrane; Dolichol Phosphates; Galactosamine; Microsomes; Mucins; Serine; Submandibular Gland; Threonine; Uridine Diphosphate N-Acetylgalactosamine | 1980 |
Hydroxyamino acid utilization and alpha-ketobutyrate toxicity in Pseudomonas cepacia.
Topics: Butyrates; Keto Acids; L-Serine Dehydratase; Pseudomonas; Serine; Threonine; Threonine Dehydratase; Valine | 1980 |
Serine phosphate, threonine phosphate and gamma-carboxyglutamic acid in normal and experimentally induced, pathologically calcified rat skin (topical cutaneous calciphylaxis).
Topics: 1-Carboxyglutamic Acid; Animals; Calciphylaxis; Dihydrotachysterol; Disease Models, Animal; Female; Glutamates; Ovalbumin; Phosphoserine; Phosphothreonine; Rats; Serine; Skin; Skin Diseases; Threonine | 1981 |
Circular dichroism studies of synthetic Asn-X-Ser/Thr-containing peptides: Structure-glycosylation relationship.
Topics: Amino Acid Sequence; Animals; Asparagine; Cell Membrane; Chickens; Circular Dichroism; Female; Glycopeptides; In Vitro Techniques; Oviducts; Peptides; Serine; Structure-Activity Relationship; Threonine | 1981 |
Amino acid transport via the red cell anion transport system.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Alanine; Amino Acids; Biological Transport; Carrier Proteins; Cysteine; Depression, Chemical; Erythrocytes; Glycine; Humans; In Vitro Techniques; Proline; Serine; Threonine; Valine | 1981 |
Methods for the identification of N-asparaginyl and O-seryl/threonyl glycosidic linkages to aminosugars in glycoproteins.
Topics: Asparagine; Borohydrides; Carbohydrate Sequence; Dansyl Compounds; Electrophoresis; Glycoproteins; Hydrolysis; Methods; Mucins; Ovalbumin; Serine; Threonine | 1981 |
Presence of O-glycosidic linkage through serine residue in kappa-casein component from bovine mature milk.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carboxypeptidases; Caseins; Cattle; Chemical Phenomena; Chemistry; Female; Glycopeptides; Glycosides; Milk; Peptide Fragments; Pregnancy; Pronase; Serine; Threonine | 1981 |
Maturation-related change of the protein kinase activity in the rabbit red blood cells.
Topics: Animals; Casein Kinases; Cell Differentiation; Chemical Phenomena; Chemistry; Chromatography, Gel; Erythrocyte Aging; Erythrocytes; Octoxynol; Polyethylene Glycols; Protein Kinases; Rabbits; Reticulocytes; Serine; Threonine | 1981 |
13C-n.m.r.-spectral study of D-galactopyranosyl and 2-acetamido-2-deoxy-D-galactopyranosyl glycopeptides relevant to glycoproteins.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Glycopeptides; Glycoproteins; Magnetic Resonance Spectroscopy; Serine; Threonine | 1981 |
Metabolism of serine, glycine and threonine in isolated cat hepatocytes Felis domestica.
Topics: Animals; Biotransformation; Cats; Glucose; Glycine; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Serine; Threonine | 1982 |
Threonine prevents derepression of pyridoxine synthesis in Escherichia coli B.
Topics: Amino Acids, Branched-Chain; Escherichia coli; Mutation; Pyridoxine; Serine; Threonine | 1982 |
Single-site uptake of neutral amino acids into guinea-pig intestinal rings.
Topics: Amino Acids; Animals; Biological Transport; Diffusion; Guinea Pigs; In Vitro Techniques; Intestine, Small; Isoleucine; Kinetics; Phenylalanine; Serine; Threonine | 1982 |
Protein kinase and specific phosphate acceptor proteins associated with tupaia herpesvirus.
Topics: Adenosine; Adenosine Triphosphate; Animals; Herpesviridae; Hydrogen-Ion Concentration; Magnesium; Phosphorylation; Protein Kinases; Serine; Substrate Specificity; Threonine; Tupaia; Viral Proteins | 1982 |
[Amino acid imbalances in blood of pregnant women with diabetes and in blood of their newborns--limit values for screening (author's transl)].
Topics: Amino Acids; Female; Glutamates; Glycine; Humans; Infant, Newborn; Methionine; Pregnancy; Pregnancy in Diabetics; Serine; Threonine; Valine | 1982 |
Increase in glutamine content of rat midbrain induced by short-term exposure to toluene and hexane.
Topics: Animals; Chromatography, High Pressure Liquid; Glutamine; Hexanes; Male; Mesencephalon; Rats; Serine; Spectrometry, Fluorescence; Threonine; Time Factors; Toluene | 1982 |
Phosphorylation of chlamydomonas reinhardi chloroplast membrane proteins in vivo and in vitro.
Topics: Chlamydomonas; Chloroplasts; Diuron; Light; Membrane Proteins; Phosphorylation; Protein Kinases; Serine; Threonine | 1982 |
Threonine imbalance and the threonine requirement of the chicken.
Topics: Amino Acids; Animals; Body Weight; Chickens; Diet; Dose-Response Relationship, Drug; Female; Male; Nutritional Requirements; Serine; Sex Factors; Threonine; Tryptophan | 1982 |
Threonine metabolism of chicks fed threonine-imbalanced diets.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Chickens; Dose-Response Relationship, Drug; Glycine Hydroxymethyltransferase; Growth; Liver; Male; Nutritional Requirements; Serine; Threonine; Threonine Dehydratase | 1982 |
[Synthesis of the glycopeptide O-beta-D-galactopyranosyl-(1 to 3)-O-(2-acetamido-2-desoxy-alpha-D-galactopyranosyl)-(1 to 3)-L-serine and -L-threonine].
Topics: Antigens, T-Independent; Carbohydrate Conformation; Carbohydrate Sequence; Glycopeptides; Haptens; Indicators and Reagents; Serine; Threonine | 1982 |
NMR study of the rotational isomerism around the C beta-O bond in phosphorylated alpha-amino acids: PSer and PThr.
Topics: Isomerism; Magnetic Resonance Spectroscopy; Phosphoserine; Phosphothreonine; Rotation; Serine; Threonine | 1982 |
Isolation and characterization of a serine-threonine-rich galactoglycoprotein from normal human plasma.
Topics: Amino Acids; Carbohydrates; Circular Dichroism; Galactose; Glycoproteins; Humans; Molecular Weight; Protein Conformation; Serine; Solubility; Threonine | 1980 |
Limk1 is predominantly expressed in neural tissues and phosphorylates serine, threonine and tyrosine residues in vitro.
Topics: Amino Acid Sequence; Animals; Base Sequence; Central Nervous System; Chromosome Mapping; Cloning, Molecular; DNA-Binding Proteins; DNA, Complementary; Humans; Lim Kinases; Mice; Molecular Sequence Data; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Messenger; Serine; Threonine; Tyrosine | 1995 |
Nucleoprotein phosphorylated on both serine and threonine is preferentially assembled into the nucleocapsids of measles virus.
Topics: Cells, Cultured; Humans; Nucleocapsid Proteins; Nucleoproteins; Phosphorylation; Serine; Threonine; Viral Proteins; Virion | 1995 |
Functional analysis of the threonine- and serine-rich Gp-I domain of glucoamylase I from Aspergillus awamori var. kawachi.
Topics: Amino Acid Sequence; Aspergillus; Base Sequence; DNA, Fungal; Enzyme Stability; Glucan 1,4-alpha-Glucosidase; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis; Saccharomyces cerevisiae; Serine; Starch; Temperature; Threonine | 1995 |
Cloning and characterization of the Saccharomyces cerevisiae SVS1 gene which encodes a serine- and threonine-rich protein required for vanadate resistance.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Drug Resistance, Microbial; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Molecular Sequence Data; Saccharomyces cerevisiae; Serine; Threonine; Vanadates | 1995 |
Possible role for serine/threonine phosphorylation in the regulation of the heteroprotein complex between the hsp90 stress protein and the pp60v-src tyrosine kinase.
Topics: 3T3 Cells; Animals; Cell Line, Transformed; Cell Membrane; Enzyme Inhibitors; Ethers, Cyclic; HSP90 Heat-Shock Proteins; Mice; Okadaic Acid; Oncogene Protein pp60(v-src); Phosphoprotein Phosphatases; Phosphorylation; Protein-Tyrosine Kinases; Serine; Threonine | 1995 |
[Structural study of O-specific polysaccharides from Proteus mirabilis O28 and 3/6, containing amides of D-galacturonic acid with L-amino acids; C-methylation and beta-elimination at L-serine and L-threonine residues upon analysis using the methylation me
Topics: Amino Acids; Carbohydrate Sequence; Gas Chromatography-Mass Spectrometry; Hexuronic Acids; Methylation; Molecular Sequence Data; O Antigens; Oxidation-Reduction; Polysaccharides, Bacterial; Proteus mirabilis; Serine; Threonine | 1993 |
Tyrosine dephosphorylation of pp60c-src is stimulated by a serine/threonine phosphatase inhibitor.
Topics: 3T3 Cells; Animals; Enzyme Activation; Ethers, Cyclic; Fibroblasts; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Serine; Threonine; Tyrosine | 1994 |
Mutation of potential phosphorylation sites in the recombinant R domain of the cystic fibrosis transmembrane conductance regulator has significant effects on domain conformation.
Topics: Amino Acid Sequence; Chloride Channels; Circular Dichroism; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Membrane Proteins; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Serine; Substrate Specificity; Threonine | 1995 |
Hexokinase autophosphorylation: identification of a new dual specificity protein kinase.
Topics: Animals; Hexokinase; Isoenzymes; Phosphorylation; Rats; Serine; Staining and Labeling; Substrate Specificity; Threonine; Tyrosine | 1994 |
Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Colon; Colonic Neoplasms; DNA Primers; DNA, Complementary; Gene Expression; Humans; Liver; Molecular Sequence Data; Neoplasms; Phosphorylation; Polymerase Chain Reaction; Ribosomal Proteins; RNA, Messenger; RNA, Neoplasm; Sequence Homology, Amino Acid; Serine; Threonine; Zinc Fingers | 1994 |
Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1.
Topics: Alkaloids; Animals; Enzyme Inhibitors; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein Tyrosine Phosphatases; Rats; Receptor, Insulin; Serine; Staurosporine; Threonine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 1995 |
Evidence for a role of protein phosphatases 1 and 2A during early nephrogenesis.
Topics: Animals; Base Sequence; Carrier Proteins; Cell Differentiation; Cell Division; Cells, Cultured; Enzyme Inhibitors; Ethers, Cyclic; Female; Immunoblotting; In Situ Hybridization; Intracellular Signaling Peptides and Proteins; Kidney; Molecular Sequence Data; Morphogenesis; Okadaic Acid; Phosphoprotein Phosphatases; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Serine; Threonine | 1995 |
Regulation of human interleukin-8 receptor A: identification of a phosphorylation site involved in modulating receptor functions.
Topics: Alkaloids; Amino Acid Sequence; Animals; Antigens, CD; Binding Sites; DNA, Complementary; Epitopes; Humans; Interleukin-8; Molecular Sequence Data; Mutation; Phosphorylation; Precipitin Tests; Protein Kinase C; Rats; Receptors, Interleukin; Receptors, Interleukin-8A; Serine; Staurosporine; Tetradecanoylphorbol Acetate; Threonine; Tumor Cells, Cultured; Up-Regulation | 1995 |
Stereoselective synthesis of O-serinyl/threoninyl-2-acetamido-2-deoxy-alpha- or beta-glycosides.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Glycosides; Glycosylation; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Schiff Bases; Serine; Threonine | 1995 |
Bcr and Raf form a complex in vivo via 14-3-3 proteins.
Topics: 14-3-3 Proteins; Animals; Cell Line; Cell Membrane; Chlorocebus aethiops; Cytosol; DNA-Binding Proteins; Fungal Proteins; Oncogene Proteins; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcr; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Serine; Threonine; Transcription Factors; Tyrosine 3-Monooxygenase | 1995 |
The protozoan Trypanosoma cruzi has a family of genes resembling the mucin genes of mammalian cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chlorocebus aethiops; Cloning, Molecular; Codon; Genes, Protozoan; Glycosylphosphatidylinositols; Mammals; Molecular Sequence Data; Mucins; Multigene Family; Oligodeoxyribonucleotides; Protein Sorting Signals; Protozoan Proteins; Recombinant Proteins; RNA, Messenger; RNA, Protozoan; Sequence Homology, Amino Acid; Serine; Species Specificity; Threonine; Trypanosoma cruzi; Vero Cells | 1995 |
Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Amino Acids; Antigen-Antibody Complex; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Affinity; DNA Mutational Analysis; Escherichia coli; Fungal Proteins; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Molecular Sequence Data; Pheromones; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces pombe Proteins; Serine; Signal Transduction; Substrate Specificity; Threonine; Transcription Factors | 1995 |
Functional domains of the heavy metal-responsive transcription regulator MTF-1.
Topics: Base Sequence; Binding Sites; DNA; DNA-Binding Proteins; Fungal Proteins; Gene Deletion; HeLa Cells; Herpes Simplex Virus Protein Vmw65; Humans; Hydrogen-Ion Concentration; Metallothionein; Metals; Molecular Sequence Data; Mutagenesis; Plasmids; Proline; Promoter Regions, Genetic; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Serine; Threonine; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Zinc Fingers | 1995 |
Control of p62 binding to TGN38/41 by phosphorylation.
Topics: Amino Acid Sequence; Animals; Cytoplasm; Glycoproteins; Membrane Glycoproteins; Membrane Proteins; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinases; Rats; Recombinant Fusion Proteins; Serine; Threonine | 1995 |
Mechanism of insulin receptor kinase inhibition in non-insulin-dependent diabetes mellitus patients. Phosphorylation of serine 1327 or threonine 1348 is unaltered.
Topics: Aged; Aged, 80 and over; Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Middle Aged; Phosphorylation; Rats; Receptor, Insulin; Serine; Threonine | 1995 |
The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element.
Topics: Amino Acid Sequence; Binding Sites; Cells, Cultured; Cysteine; Disulfides; Extracellular Matrix; Glycine; Humans; Kinetics; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Receptors, Glycine; Serine; Strychnine; Taurine; Threonine; Tyrosine | 1995 |
Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Cloning, Molecular; DNA, Complementary; Escherichia coli; Humans; Molecular Sequence Data; Phosphorylation; Protein Kinases; Recombinant Proteins; Serine; tau Proteins; Threonine | 1995 |
Inhibition of serine/threonine protein phosphatases by secretagogues in insulin-secreting cells.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Arginine; Glutamine; Insulin; Insulin Secretion; Insulinoma; Phosphoprotein Phosphatases; Serine; Threonine; Tumor Cells, Cultured | 1995 |
A potent inhibitor of endothelial cell proliferation is generated by proteolytic cleavage of the chemokine platelet factor 4.
Topics: Amino Acid Sequence; Animals; Aorta; Cattle; Cells, Cultured; Culture Media, Conditioned; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Fetus; Growth Inhibitors; Heart; Humans; Kinetics; Leukocytes; Models, Structural; Molecular Sequence Data; Peptide Fragments; Platelet Factor 4; Protein Structure, Secondary; Serine; Threonine | 1995 |
Mutational analysis of the ganglioside-binding activity of the type II Escherichia coli heat-labile enterotoxin LT-IIb.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Bacterial Toxins; Base Sequence; Dose-Response Relationship, Drug; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Gangliosides; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Radioimmunoassay; Recombinant Fusion Proteins; Sequence Alignment; Serine; Threonine; Transformation, Bacterial | 1995 |
Characterization of Ca2+/calmodulin-dependent protein kinase II from smooth muscle.
Topics: Amino Acid Sequence; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Chickens; Cyanogen Bromide; Gizzard, Avian; Isoenzymes; Kinetics; Molecular Sequence Data; Molecular Weight; Muscle, Smooth; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphorylation; Sequence Homology, Amino Acid; Serine; Threonine; Trypsin | 1995 |
Insulin regulates serine/threonine phosphorylation in activated human B lymphocytes.
Topics: Antigens, CD; Antigens, CD20; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Casein Kinases; Humans; Insulin; Lymphocyte Activation; Palatine Tonsil; Phosphorylation; Protein Kinases; Receptor, Insulin; Serine; Threonine | 1993 |
Phosphorylation of tobacco mosaic virus cell-to-cell movement protein by a developmentally regulated plant cell wall-associated protein kinase.
Topics: Amino Acid Sequence; Cell Wall; DNA Mutational Analysis; DNA, Single-Stranded; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Viral; Genes; Genes, Viral; Molecular Sequence Data; Nicotiana; Phosphorylation; Plant Viral Movement Proteins; Plants, Genetically Modified; Plants, Toxic; Protein Kinases; Recombinant Proteins; RNA; Serine; Threonine; Tobacco Mosaic Virus; Viral Proteins | 1993 |
Rapid phosphorylation and selective dephosphorylation of P-selectin accompanies platelet activation.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Cell Adhesion Molecules; Cells, Cultured; Collagen; Epinephrine; Humans; Kinetics; Molecular Sequence Data; Oligopeptides; P-Selectin; Phosphorylation; Platelet Activation; Platelet Membrane Glycoproteins; Serine; Threonine; Thrombin; Tyrosine | 1993 |
Regional differences in pig gastric mucins.
Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Cardia; Dithiothreitol; Gastric Fundus; Gastric Mucins; Oligosaccharides; Oxidation-Reduction; Proline; Pylorus; Serine; Swine; Threonine | 1993 |
Requirement of serine phosphorylation for formation of STAT-promoter complexes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Nucleus; Ciliary Neurotrophic Factor; Cytoplasm; DNA; DNA-Binding Proteins; Humans; Interleukin-6; Isoquinolines; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Phosphorylation; Piperazines; Promoter Regions, Genetic; Serine; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Threonine; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 1995 |
Dopamine- and cAMP-regulated phosphoprotein DARPP-32: phosphorylation of Ser-137 by casein kinase I inhibits dephosphorylation of Thr-34 by calcineurin.
Topics: Amino Acid Sequence; Animals; Calcineurin; Calcium; Calmodulin; Calmodulin-Binding Proteins; Casein Kinases; Cattle; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Kinetics; Manganese; Muscle, Skeletal; Myocardium; Nerve Tissue Proteins; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinases; Protein Phosphatase 1; Rabbits; Rats; Recombinant Proteins; Serine; Substantia Nigra; Threonine; Thymus Gland | 1995 |
Ser/Thr-rich repetitive motifs as targets for phosphoglycan modifications in Leishmania mexicana secreted acid phosphatase.
Topics: Acid Phosphatase; Amino Acid Sequence; Animals; Base Sequence; Carbohydrate Sequence; Cloning, Molecular; DNA, Protozoan; Genes, Protozoan; Leishmania mexicana; Lysosomes; Molecular Sequence Data; Oligosaccharides; Protozoan Proteins; Recombinant Fusion Proteins; Repetitive Sequences, Nucleic Acid; RNA, Messenger; RNA, Protozoan; Sequence Alignment; Sequence Analysis, DNA; Sequence Deletion; Serine; Threonine | 1995 |
In vivo sulfhydryl modification of the ligand-binding site of Tsr, the Escherichia coli serine chemoreceptor.
Topics: Bacterial Proteins; Binding Sites; Cysteine; Escherichia coli; Ethylmaleimide; Ligands; Membrane Proteins; Mutagenesis, Site-Directed; Serine; Threonine | 1995 |
Platelet talin is phosphorylated by calyculin A.
Topics: Alkalies; Antibodies, Monoclonal; Blood Platelets; Electrophoresis, Polyacrylamide Gel; Humans; Isotope Labeling; Marine Toxins; Oxazoles; Peptides; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Precipitin Tests; Serine; Talin; Threonine; Tyrosine | 1995 |
Structural requirements for addition of O-linked carbohydrate to recombinant erythropoietin.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cell Line; Chlorocebus aethiops; CHO Cells; Chromatography, High Pressure Liquid; Cloning, Molecular; Cricetinae; Disulfides; Erythropoietin; Genetic Variation; Glycosylation; Humans; Isoelectric Focusing; Molecular Sequence Data; Mutagenesis, Site-Directed; Neuraminidase; Oligosaccharides; Peptide Fragments; Point Mutation; Recombinant Proteins; Serine; Threonine; Transfection | 1994 |
Synthesis of the glycosyl amino acids N alpha-Fmoc-Ser[Ac4-beta-D-Galp-(1-->3)-Ac2-alpha-D-GalN3p]-OPfp and N alpha-Fmoc-Thr[Ac4-beta-D-Galp-(1-->3)-Ac2-alpha-D-GalN3p]-OPfp and the application in the solid-phase peptide synthesis of multiply glycosylated
Topics: Amino Acid Sequence; Antigens; Azides; Carbohydrate Conformation; Carbohydrate Sequence; Disaccharides; Galactose; Glycopeptides; Glycosylation; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mucins; Serine; Threonine | 1995 |
Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase.
Topics: Amino Acid Sequence; Base Sequence; Centrosome; Genes, Fungal; Genes, Lethal; Genomic Library; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Threonine; Tyrosine | 1995 |
The rubella virus RNA binding activity of human calreticulin is localized to the N-terminal domain.
Topics: Animals; Calcium-Binding Proteins; Calreticulin; Carrier Proteins; Chlorocebus aethiops; Maltose; Maltose-Binding Proteins; Phosphorylation; Recombinant Fusion Proteins; Ribonucleoproteins; RNA-Binding Proteins; RNA, Viral; Rubella virus; Serine; Threonine; Vero Cells | 1995 |
Glycosylation of the c-Myc transactivation domain.
Topics: Acetylglucosamine; Amidohydrolases; Animals; Binding Sites; Cattle; Cell Line; CHO Cells; Chromatography, Affinity; Cloning, Molecular; Cricetinae; Glycoside Hydrolases; Glycosylation; Helix-Loop-Helix Motifs; Humans; Leucine Zippers; Macromolecular Substances; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Protein Biosynthesis; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc; Rats; Recombinant Proteins; Sequence Deletion; Serine; Spodoptera; Threonine; Transcriptional Activation; Transfection | 1995 |
Phosphorylation site-specific antibodies to cardiac phospholamban.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Antibody Specificity; Calcium-Binding Proteins; Molecular Sequence Data; Myocardium; Phosphorylation; Phosphoserine; Phosphothreonine; Rabbits; Rats; Serine; Threonine | 1995 |
Mutational analysis of the putative substrate-binding site of 3C proteinase of coxsackievirus B3.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Conserved Sequence; DNA Primers; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enterovirus B, Human; Escherichia coli; Glycine; Histidine; Molecular Sequence Data; Mutation; Sequence Alignment; Serine; Threonine | 1995 |
A vector projection method for predicting the specificity of GalNAc-transferase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Glycosylation; Humans; In Vitro Techniques; Molecular Sequence Data; N-Acetylgalactosaminyltransferases; Peptide Fragments; Serine; Threonine | 1995 |
The saccharides of the MUC 1 mucin-type glycoprotein, epitectin, produced by H.Ep.2 cells in the presence of aryl-N-acetyl-alpha-galactosaminides.
Topics: Acetylgalactosamine; Antigens, Tumor-Associated, Carbohydrate; Carbohydrate Conformation; Carbohydrate Sequence; Cell Line; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Glucosamine; Humans; Laryngeal Neoplasms; Membrane Glycoproteins; Molecular Sequence Data; Molecular Weight; Mucin-1; Mucins; Neoplasm Proteins; Oligosaccharides; Serine; Threonine; Tritium; Tumor Cells, Cultured | 1995 |
Tau protein kinase I/GSK-3 beta/kinase FA in heparin phosphorylates tau on Ser199, Thr231, Ser235, Ser262, Ser369, and Ser400 sites phosphorylated in Alzheimer disease brain.
Topics: Alzheimer Disease; Amino Acid Sequence; Animals; Brain; Cattle; Glycogen Synthase Kinase 3; Heparin; Microtubules; Molecular Sequence Data; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Serine; Swine; tau Proteins; Threonine; Trypsin | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
The p60 tumor necrosis factor (TNF) receptor-associated kinase (TRAK) binds residues 344-397 within the cytoplasmic domain involved in TNF signaling.
Topics: Binding Sites; Cell Line; Glutathione Transferase; Humans; Kinetics; Mutagenesis; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Restriction Mapping; Sequence Deletion; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha | 1995 |
Phosphorylation of CTP synthetase from Saccharomyces cerevisiae by protein kinase C.
Topics: Adenosine Triphosphate; Autoradiography; Carbon-Nitrogen Ligases; Kinetics; Ligases; Phosphates; Phosphopeptides; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase C; Saccharomyces cerevisiae; Serine; Threonine | 1995 |
Persistent enhancement of sustained calcium-dependent glutamate release by phorbol esters: role of calmodulin-independent serine/threonine phosphorylation and actin disassembly.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Alkaloids; Animals; Barium; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cytochalasin D; Ethers, Cyclic; Glutamates; Guinea Pigs; Hippocampus; Isoquinolines; Male; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Phosphotransferases; Piperazines; Protein Kinase C; Serine; Sphingosine; Staurosporine; Subcellular Fractions; Sulfonamides; Synaptosomes; Threonine | 1995 |
A single amino acid of the human gamma-aminobutyric acid type A receptor gamma 2 subunit determines benzodiazepine efficacy.
Topics: Animals; Benzodiazepines; Humans; Point Mutation; Receptors, GABA-A; Serine; Threonine; Xenopus laevis | 1994 |
Analysis of antigenic surfaces of proteins.
Topics: Amino Acids; Antigens, Surface; Antigens, Viral; Binding Sites, Antibody; Biological Evolution; Capsid; Immunoglobulin Fragments; Models, Molecular; Picornaviridae; Proteins; Serine; Threonine | 1995 |
Overexpression of the yeast MCK1 protein kinase suppresses conditional mutations in centromere-binding protein genes CBF2 and CBF5.
Topics: Fungal Proteins; Gene Dosage; Gene Expression Regulation, Fungal; Genes, Fungal; Glycogen Synthase Kinase 3; Hydro-Lyases; Microtubule-Associated Proteins; Phosphorylation; Protein-Tyrosine Kinases; Ribonucleoproteins; Ribonucleoproteins, Small Nuclear; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Suppression, Genetic; Temperature; Threonine | 1995 |
Hormone-induced hyperphosphorylation of specific phosphorylated sites in the mouse glucocorticoid receptor.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Kinetics; Mice; Phosphopeptides; Phosphorylation; Receptors, Glucocorticoid; Serine; Threonine; Triamcinolone Acetonide | 1995 |
Tyrosine phosphorylation of measles virus nucleocapsid protein in persistently infected neuroblastoma cells.
Topics: 2',5'-Oligoadenylate Synthetase; Capsid; eIF-2 Kinase; Humans; Measles virus; Neuroblastoma; Nucleocapsid Proteins; Nucleoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Cells, Cultured; Tyrosine; Viral Proteins | 1995 |
Different sites of acivicin binding and inactivation of gamma-glutamyl transpeptidases.
Topics: Alanine; Amino Acid Sequence; Animals; Antimetabolites; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; gamma-Glutamyltransferase; Humans; Hydroxylamine; Hydroxylamines; Isoxazoles; Kidney; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Rats; Recombinant Proteins; Restriction Mapping; Serine; Swine; Threonine | 1995 |
Effects of diet-induced hyperthreoninemia. II). Tissue and extracellular amino acid levels in the brain.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Diet; Glutamates; Glutamic Acid; Glycine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Threonine | 1994 |
Phosphorylation of a P-glycoprotein homologue in Plasmodium falciparum.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium; Carrier Proteins; Erythrocytes; Fluorescent Antibody Technique; Humans; Membrane Glycoproteins; Phosphorylation; Plasmodium falciparum; Protein Kinases; Serine; Threonine | 1993 |
Dietary pectin's effect on ileal and fecal amino acid digestibility and exocrine pancreatic secretions in growing pigs.
Topics: alpha-Amylases; Amino Acids; Animals; Aspartic Acid; Dietary Fiber; Digestion; Feces; Glutamates; Glutamic Acid; Glycine; Ileum; Male; Pancreas; Pancreatic Juice; Pectins; Phenylalanine; Proline; Serine; Swine; Threonine; Trypsin; Valine | 1994 |
Functional analysis of phosphorylation sites in human lamin A controlling lamin disassembly, nuclear transport and assembly.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Line; Cell Nucleus; Chick Embryo; DNA; Fluorescent Antibody Technique; Humans; Lamin Type A; Lamins; Mitosis; Molecular Sequence Data; Mutation; Nuclear Proteins; Phenotype; Phosphorylation; Protein Kinase C; Serine; Threonine; Transfection | 1993 |
Phorbol ester stimulates phosphorylation on serine 1327 of the human insulin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cells, Cultured; Humans; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine | 1994 |
Stage-specific regulation of protein phosphorylation in Leishmania major.
Topics: Animals; In Vitro Techniques; Leishmania major; Molecular Weight; Phosphorylation; Protein Kinases; Protozoan Proteins; Serine; Signal Transduction; Threonine; Tyrosine | 1994 |
Polyomavirus middle-sized tumor antigen modulates c-Jun phosphorylation and transcriptional activity.
Topics: 3T3 Cells; Animals; Antigens, Polyomavirus Transforming; Chloramphenicol O-Acetyltransferase; Gene Expression; Genes, jun; Genes, ras; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-raf; Proto-Oncogenes; ras Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine; Transcription, Genetic; Transfection | 1994 |
Histidine ammonia-lyase mutant S143C is posttranslationally converted into fully active wild-type enzyme. Evidence for serine 143 to be the precursor of active site dehydroalanine.
Topics: Alanine; Base Sequence; Cysteine; Histidine Ammonia-Lyase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Protein Precursors; Protein Processing, Post-Translational; Pseudomonas putida; Recombinant Proteins; Serine; Structure-Activity Relationship; Sulfhydryl Compounds; Threonine | 1994 |
Site-specific anti-phosphopeptide antibodies: use in assessing insulin receptor serine/threonine phosphorylation state and identification of serine-1327 as a novel site of phorbol ester-induced phosphorylation.
Topics: Amino Acid Sequence; Animals; Antibodies; CHO Cells; Cricetinae; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine | 1994 |
Substrate recognition by casein kinase-II: the role of histidine-160.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Baculoviridae; Base Sequence; Binding Sites; Casein Kinase II; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Spodoptera; Structure-Activity Relationship; Substrate Specificity; Threonine | 1994 |
Modulation of complement regulatory function and measles virus receptor function by the serine-threonine-rich domains of membrane cofactor protein (CD46).
Topics: Animals; Antigens, CD; Base Sequence; CHO Cells; Complement Inactivator Proteins; Cricetinae; DNA, Complementary; Flow Cytometry; Gene Transfer Techniques; Humans; Immunoblotting; Membrane Cofactor Protein; Membrane Glycoproteins; Molecular Sequence Data; Serine; Threonine | 1994 |
A serine-to-threonine substitution in the triazine herbicide-binding protein in potato cells results in atrazine resistance without impairing productivity.
Topics: Amino Acid Sequence; Atrazine; Bacterial Proteins; Base Sequence; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Electron Transport; Genes, Plant; Molecular Sequence Data; Photosynthesis; Photosystem II Protein Complex; Plant Proteins; Point Mutation; Serine; Solanum tuberosum; Threonine | 1993 |
Sequencing and characterization of the sdaC gene and identification of the sdaCB operon in Escherichia coli K12.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Biological Transport; Carrier Proteins; Cyclic AMP Receptor Protein; DNA-Binding Proteins; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Leucine-Responsive Regulatory Protein; Membrane Proteins; Molecular Sequence Data; Operon; Plasmids; Serine; Threonine; Transcription Factors | 1994 |
Stereoselective synthesis of beta-D-glycopyranosyl-L-serinate or -threoninate derivatives with an unusual migration.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Glycopeptides; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Serine; Spectrometry, Mass, Fast Atom Bombardment; Stereoisomerism; Structure-Activity Relationship; Threonine | 1994 |
[In vitro NMR spectroscopy of healthy, pathologically changed and carcinomatous breast tissue samples correlated with histological findings].
Topics: Breast; Breast Diseases; Breast Neoplasms; Diagnosis, Differential; Fatty Acids; Female; Glucose; Glycine; Humans; In Vitro Techniques; Inositol; Magnetic Resonance Spectroscopy; Serine; Sucrose; Threonine | 1994 |
Increased phosphorylation of HP1, a heterochromatin-associated protein of Drosophila, is correlated with heterochromatin assembly.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Drosophila melanogaster; Electrophoresis, Gel, Two-Dimensional; Female; Heterochromatin; Larva; Male; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Serine; Threonine | 1994 |
Mutagenesis of the cyclic AMP receptor protein of Escherichia coli: targeting positions 83, 127 and 128 of the cyclic nucleotide binding pocket.
Topics: Base Sequence; beta-Galactosidase; Binding Sites; Cross-Linking Reagents; Cyclic AMP; Cysteine; Dithionitrobenzoic Acid; Escherichia coli; Glycine; Isoleucine; Molecular Sequence Data; Mutagenesis; Receptors, Cyclic AMP; Serine; Structure-Activity Relationship; Threonine; Transcription, Genetic | 1994 |
Truncation of the receptor carboxyl terminus impairs agonist-dependent phosphorylation and desensitization of the alpha 1B-adrenergic receptor.
Topics: Animals; Cell Line; Cell Membrane; Chlorocebus aethiops; Epinephrine; Fibroblasts; Indoles; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphatidylinositol Phosphates; Phosphorylation; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Sequence Deletion; Serine; Threonine; Transfection | 1994 |
Identification and characterization of O-biotinylated hydroxy amino acid residues in peptides.
Topics: Amino Acid Sequence; Amyloid; Biotin; Chromatography, High Pressure Liquid; Chymotrypsin; Humans; Hydroxylamine; Hydroxylamines; Indicators and Reagents; Islet Amyloid Polypeptide; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Peptides; Serine; Spectrometry, Mass, Fast Atom Bombardment; Threonine | 1994 |
Identification of sites of serine and threonine phosphorylation via site-directed mutagenesis--site transformation versus site elimination.
Topics: Adenosine Triphosphate; Animals; Humans; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Biosynthesis; Protein Kinases; Proteins; Radioisotope Dilution Technique; Recombinant Proteins; Serine; Threonine | 1994 |
Alteration of the enzymatic specificity of human angiogenin by site-directed mutagenesis.
Topics: Angiogenesis Inducing Agents; Animals; Base Sequence; Chick Embryo; Glutamates; Glutamic Acid; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Proteins; Ribonuclease, Pancreatic; Serine; Substrate Specificity; Threonine | 1993 |
An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Male; Microinjections; Nerve Degeneration; Niacin; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serine; Threonine | 1993 |
Dipeptidyl peptidase IV (DPP-IV) from pig kidney cleaves analogs of bovine growth hormone-releasing factor (bGRF) modified at position 2 with Ser, Thr or Val. Extended DPP-IV substrate specificity?
Topics: Animals; Buffers; Cattle; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Growth Hormone-Releasing Hormone; Half-Life; Kidney; Serine; Substrate Specificity; Swine; Threonine; Valine | 1993 |
Serine/threonine protein kinases and calcium-dependent protease in senescent IMR-90 fibroblasts.
Topics: Calcium; Calpain; Cell Line; Cellular Senescence; Diploidy; Endopeptidases; Fibroblasts; Humans; Osmolar Concentration; Protein Kinase C; Protein Kinases; Serine; Threonine | 1993 |
Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling.
Topics: 3T3 Cells; Adipocytes; Animals; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Glucose; Insulin; Insulin Receptor Substrate Proteins; Mice; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Receptor, Insulin; Serine; Signal Transduction; Threonine; Tyrosine | 1994 |
Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; DNA Primers; DNA, Complementary; Epithelium; G-Protein-Coupled Receptor Kinase 5; GTP-Binding Proteins; Male; Molecular Sequence Data; Mouth Mucosa; Organ Specificity; Peptide Fragments; Phosphorylation; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Restriction Mapping; Rhodopsin; RNA, Messenger; Serine; Taste; Threonine | 1994 |
Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.
Topics: Amino Acid Sequence; Conserved Sequence; Enzyme Activation; Fungal Proteins; Glutathione Transferase; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphopeptides; Phosphorylation; Point Mutation; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Serine; Threonine | 1994 |
An inducible NADP(+)-dependent D-phenylserine dehydrogenase from Pseudomonas syringae NK-15: purification and biochemical characterization.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Bacterial Proteins; Coenzymes; Hydrogen-Ion Concentration; Isomerism; Kinetics; Molecular Sequence Data; Molecular Weight; NADPH Dehydrogenase; Pseudomonas; Serine; Substrate Specificity; Threonine | 1993 |
Phosphorylation of the duck hepatitis B virus capsid protein associated with conformational changes in the C terminus.
Topics: Amino Acid Sequence; Animals; Capsid; Codon; Ducks; Hepatitis B Virus, Duck; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphopeptides; Phosphorylation; Point Mutation; Protein Conformation; Protein Processing, Post-Translational; Serine; Threonine | 1994 |
Insulin receptor mutation at tyrosines 1162 and 1163 alters both receptor serine phosphorylation and desensitization.
Topics: Animals; CHO Cells; Cricetinae; Desensitization, Immunologic; Glycogen; Humans; Insulin; Mutation; Phosphorylation; Protein Kinase C; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1994 |
Comparative roles of histidine 51 in human beta 1 beta 1 and threonine 51 in pi pi alcohol dehydrogenases.
Topics: Alcohol Dehydrogenase; Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; DNA, Complementary; Genetic Variation; Genotype; Histidine; Humans; Hydrogen Bonding; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Serine; Threonine | 1994 |
Characterization of recombinant Xenopus MAP kinase kinases mutated at potential phosphorylation sites.
Topics: Amino Acid Sequence; Animals; Base Sequence; DNA Primers; Enzyme Activation; Fungal Proteins; Humans; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Recombinant Proteins; Schizosaccharomyces pombe Proteins; Sequence Alignment; Serine; Threonine; Transcription Factors; Xenopus | 1994 |
Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Topics: Alanine; Amino Acid Sequence; Bacteriophage T4; Calorimetry; Circular Dichroism; Enzyme Stability; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Serine; Threonine; Valine | 1993 |
Study of wild type and genetically modified reaction centers from Rhodobacter capsulatus: structural comparison with Rhodopseudomonas viridis and Rhodobacter sphaeroides.
Topics: Alanine; Amino Acid Sequence; Benzoquinones; Isoleucine; Kinetics; Light-Harvesting Protein Complexes; Mathematics; Mutagenesis, Site-Directed; Phenanthrolines; Photosynthetic Reaction Center Complex Proteins; Rhodobacter capsulatus; Rhodobacter sphaeroides; Rhodopseudomonas; Serine; Threonine | 1993 |
Microsequence analysis of the N-terminally blocked proteins immobilized on polyvinylidene difluoride membrane by western blotting.
Topics: Acetylation; Amino Acid Sequence; Animals; Blotting, Western; Cytochrome c Group; Geotrichum; Lipase; Membranes, Artificial; Microchemistry; Molecular Sequence Data; Peptide Fragments; Polyvinyls; Proteins; Pyrrolidonecarboxylic Acid; Sequence Analysis; Serine; Superoxide Dismutase; Threonine; Trypsin; Tryptophan Synthase | 1993 |
The acceptor substrate specificity of porcine submaxillary UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is dependent on the amino acid sequences adjacent to serine and threonine residues.
Topics: Amino Acid Sequence; Animals; Erythropoietin; Glycosylation; Molecular Sequence Data; Mucins; N-Acetylgalactosaminyltransferases; Serine; Structure-Activity Relationship; Submandibular Gland; Substrate Specificity; Swine; Threonine | 1993 |
Partial characterization of an approximately 20 K M(r) retinal protein whose phosphorylation is inhibited by taurine.
Topics: Animals; Dose-Response Relationship, Drug; Eye Proteins; Mitochondria; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Retina; Serine; Taurine; Threonine | 1993 |
Hb Villaverde [beta 89 (F5) Ser-->Thr]: the structural modification of an intrasubunit contact is responsible for a high oxygen affinity.
Topics: Adult; Amino Acid Sequence; Blood Cell Count; Child, Preschool; Hematocrit; Hemoglobins, Abnormal; Humans; Male; Mass Spectrometry; Molecular Sequence Data; Oxygen; Peptide Fragments; Polycythemia; Serine; Threonine; Trypsin | 1993 |
Effects of diet-induced hyperthreoninemia. I). Amino acid levels in the central nervous system and peripheral tissues.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Central Nervous System; Chromatography, High Pressure Liquid; Glycine; Liver; Male; Muscles; Rats; Rats, Sprague-Dawley; Serine; Threonine; Threonine Dehydratase | 1993 |
A regulatory element in the CHA1 promoter which confers inducibility by serine and threonine on Saccharomyces cerevisiae genes.
Topics: Base Sequence; Chromosome Mapping; DNA, Fungal; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Regulator; L-Serine Dehydratase; Molecular Sequence Data; Mutagenesis; Promoter Regions, Genetic; Protein Binding; Saccharomyces cerevisiae; Sequence Deletion; Serine; Threonine | 1993 |
A comparison of serine and threonine O-glycosylation by UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase.
Topics: Acetylgalactosamine; Amino Acid Sequence; Animals; Circular Dichroism; Colostrum; Erythropoietin; Female; Glycosylation; Humans; Kidney; Liver; Male; Molecular Sequence Data; N-Acetylgalactosaminyltransferases; Polypeptide N-acetylgalactosaminyltransferase; Rats; Rats, Wistar; Salivary Glands; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine; von Willebrand Factor | 1993 |
Substrate specificity of protein kinase C studied with peptides containing D-amino acid residues.
Topics: Amino Acid Sequence; Kinetics; Molecular Sequence Data; Oligopeptides; Phosphorylation; Protein Kinase C; Serine; Stereoisomerism; Substrate Specificity; Threonine | 1993 |
Insulin and tumor-promoting agent regulate an inhibitor of the 44-kDa mitogen-activated protein kinase/extracellular signal-regulated protein kinase 1 in fibroblasts.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Enzyme Activation; Humans; Insulin; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Weight; Phosphorylation; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Serine; Threonine; Transfection | 1993 |
Role of hydroxyl-bearing amino acids in differentially tuning the absorption spectra of the human red and green cone pigments.
Topics: Cell Line; Humans; Light; Models, Molecular; Mutagenesis, Site-Directed; Photoreceptor Cells; Polymorphism, Genetic; Recombinant Proteins; Retinal Pigments; Serine; Spectrophotometry; Threonine; Transfection; Tyrosine | 1993 |
Co-crystallization of the catalytic subunit of the serine/threonine specific protein phosphatase 1 from human in complex with microcystin LR.
Topics: Crystallization; Crystallography, X-Ray; Humans; Marine Toxins; Microcystins; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Phosphatase 1; Serine; Threonine | 1994 |
Interaction of a novel Tn (GalNAc alpha 1-->Ser/Thr) glycoprotein with Gal, GalNAc and GlcNAc specific lectins.
Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Armadillos; Carbohydrate Sequence; Galactose; Glycoproteins; Lectins; Molecular Sequence Data; Serine; Submandibular Gland; Threonine | 1994 |
Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Genes, ras; Humans; Mice; Molecular Sequence Data; Phosphorylation; Proto-Oncogene Proteins c-myc; Rats; Serine; Threonine | 1994 |
Identification and structural analysis of the tetrasaccharide NeuAc alpha(2-->6)Gal beta(1-->4)GlcNAc beta(1-->3)Fuc alpha 1-->O-linked to serine 61 of human factor IX.
Topics: Amino Acid Sequence; Carbohydrate Conformation; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Factor IX; Fucose; Glycopeptides; Glycoside Hydrolases; Humans; Molecular Sequence Data; Oligosaccharides; Peptide Fragments; Serine; Threonine | 1993 |
[Side reactions in peptide synthesis. V. O-sulfonation of serine and threonine during removal of pmc- and mtr-protecting groups from arginine residues in fmoc-solid phase synthesis].
Topics: Amino Acid Sequence; Arginine; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Free Radical Scavengers; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Peptides; Serine; Spectrophotometry, Infrared; Threonine | 1993 |
Protein O-mannosylation in Candida albicans. Determination of the amino acid sequences of peptide acceptors for protein O-mannosyltransferase.
Topics: Amino Acid Sequence; Amino Acids; Biotin; Candida albicans; Cell Membrane; Mannose; Mannosyltransferases; Molecular Sequence Data; Oligopeptides; Serine; Threonine | 1993 |
Purification, cloning, and expression of a bovine UDP-GalNAc: polypeptide N-acetyl-galactosaminyltransferase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cell Line; Cloning, Molecular; Colostrum; DNA; Female; Glycosylation; Molecular Sequence Data; N-Acetylgalactosaminyltransferases; Placenta; Polymerase Chain Reaction; Polypeptide N-acetylgalactosaminyltransferase; Recombinant Proteins; RNA, Messenger; Serine; Threonine; Transfection | 1993 |
Bombesin and epidermal growth factor stimulate the mitogen-activated protein kinase through different pathways in Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Mice; Phosphorylation; Protein Kinase C; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1993 |
Identification of a serine/threonine-specific protein phosphatase from the archaebacterium Sulfolobus solfataricus.
Topics: Enzyme Activation; Phosphoprotein Phosphatases; Serine; Sulfolobus; Threonine | 1993 |
Sequencing and characterization of the sdaB gene from Escherichia coli K-12.
Topics: Amino Acid Sequence; Base Sequence; beta-Galactosidase; Binding Sites; Chromosomes, Bacterial; Cloning, Molecular; Codon; Cyclic AMP Receptor Protein; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Genotype; Isoenzymes; Kinetics; L-Serine Dehydratase; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Open Reading Frames; Plasmids; Promoter Regions, Genetic; Recombinant Fusion Proteins; Ribosomes; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serine; Threonine | 1993 |
Biochemical, genetic, and functional analyses of the phosphorylation sites on the Epstein-Barr virus-encoded oncogenic latent membrane protein LMP-1.
Topics: Amino Acid Sequence; Animals; Cell Transformation, Viral; Chromobox Protein Homolog 5; DNA Mutational Analysis; Fibroblasts; Herpesvirus 4, Human; Molecular Sequence Data; Oncogene Proteins, Viral; Peptide Fragments; Phosphopeptides; Phosphorylation; Protein Processing, Post-Translational; Rats; Serine; Signal Transduction; Threonine; Viral Matrix Proteins | 1993 |
Transactivation of gene expression by Myc is inhibited by mutation at the phosphorylation sites Thr-58 and Ser-62.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chlorocebus aethiops; Codon; DNA; Gene Expression; Genes, myc; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Plasmids; Point Mutation; Polymerase Chain Reaction; Protein Kinases; Proto-Oncogene Proteins c-myc; Serine; Substrate Specificity; Threonine; Transcriptional Activation | 1993 |
Functional correlation between the Ser/Thr-phosphorylation of band-3 and band-3-mediated transmembrane anion transport in human erythrocytes.
Topics: Anion Exchange Protein 1, Erythrocyte; Biological Transport; Erythrocytes; Ethers, Cyclic; Humans; Okadaic Acid; Oxalates; Phosphoprotein Phosphatases; Phosphorylation; Serine; Threonine | 1993 |
The functional effects of mutations Thr673-->Asp and Ser702-->Asp at the Pro-directed kinase phosphorylation sites in the C-terminus of chicken gizzard caldesmon.
Topics: Actins; Animals; Aspartic Acid; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Calmodulin-Binding Proteins; CDC2 Protein Kinase; Chickens; Electrophoresis, Polyacrylamide Gel; Gene Expression; Gizzard, Avian; Molecular Sequence Data; Phosphorylation; Point Mutation; Polymerase Chain Reaction; Protein Kinases; Serine; Structure-Activity Relationship; Threonine; Tropomyosin | 1993 |
Serines and threonines in the gastrin-releasing peptide receptor carboxyl terminus mediate internalization.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Bombesin; CHO Cells; Cloning, Molecular; Cricetinae; DNA; Fibroblasts; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Bombesin; Receptors, Neurotransmitter; Recombinant Proteins; Sequence Deletion; Serine; Threonine; Transfection | 1993 |
Modulation of allosteric interactions in neurophysin induced by succinylation of serine-56 or cleavage of residues 1-8.
Topics: Allosteric Site; Amino Acid Sequence; Animals; Cattle; Kinetics; Molecular Sequence Data; Neurophysins; Peptide Fragments; Peptide Mapping; Protein Structure, Secondary; Serine; Succinic Anhydrides; Threonine | 1993 |
Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine.
Topics: Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Glycogen Synthase Kinase 3; Phosphorylation; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 1993 |
Tau protein kinase II is involved in the regulation of the normal phosphorylation state of tau protein.
Topics: Aging; Amino Acid Sequence; Animals; Brain; Cattle; Cyclin-Dependent Kinase 5; Electrophoresis, Gel, Two-Dimensional; Enzyme-Linked Immunosorbent Assay; Immune Sera; Immunoblotting; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Substrate Specificity; tau Proteins; Threonine | 1993 |
Side reaction during the deprotection of (S-acetamidomethyl)cysteine in a peptide with a high serine and threonine content.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; Chemistry, Organic; Cobra Neurotoxin Proteins; Cystine; Ferricyanides; Fluoroacetates; Iodine; Mercury; Molecular Sequence Data; Peptide Fragments; Serine; Snakes; Thallium; Threonine; Trifluoroacetic Acid | 1993 |
A high-performance liquid chromatography assay for threonine/serine dehydratase.
Topics: Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Keto Acids; Phenylenediamines; Plants; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Threonine; Threonine Dehydratase | 1993 |
Replacement of Thr-303 of P450 2E1 with serine modifies the regioselectivity of its fatty acid hydroxylase activity.
Topics: Animals; Base Sequence; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Fatty Acids; Hydroxylation; Laurates; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases, N-Demethylating; Rabbits; Serine; Spectrophotometry, Ultraviolet; Threonine; Valine | 1993 |
Serine- and threonine-rich domain regulates internalization of muscarinic cholinergic receptors.
Topics: Amino Acid Sequence; Carbachol; Cell Line; Down-Regulation; Humans; Molecular Sequence Data; Mutagenesis; Phosphorylation; Protein Structure, Secondary; Receptors, Muscarinic; Serine; Threonine | 1993 |
Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck.
Topics: Amino Acid Sequence; Cell Line; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; HeLa Cells; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptide Mapping; Peptides; Phosphopeptides; Phosphorylation; Phosphoserine; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine | 1993 |
Pro-major basic protein has three types of sugar chains at the pro-portion.
Topics: Amino Acid Sequence; Animals; Asparagine; Blood Proteins; Cricetinae; Eosinophil Granule Proteins; Glycopeptides; Glycoproteins; Glycosylation; Molecular Sequence Data; Monosaccharides; Peptide Mapping; Protein Precursors; Protein Processing, Post-Translational; Protein Sorting Signals; Ribonucleases; Sequence Analysis; Serine; Serine Endopeptidases; Threonine | 1993 |
M-phase-specific phosphorylation of the POU transcription factor GHF-1 by a cell cycle-regulated protein kinase inhibits DNA binding.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Cycle; Cell Line; Chlorocebus aethiops; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Activation; Growth Hormone; HeLa Cells; Homeodomain Proteins; Homeostasis; Humans; Mitosis; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Mapping; Phosphopeptides; Phosphorylation; Pituitary Gland, Anterior; Prolactin; Recombinant Proteins; Serine; Threonine; Transcription Factor Pit-1; Transcription Factors; Transfection | 1995 |
Hierarchal constitutive phosphorylation of the vesicular stomatitis virus P protein and lack of effect on P1 to P2 conversion.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Cell Line; DNA-Directed RNA Polymerases; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Phosphates; Phosphoproteins; Phosphorylation; RNA-Dependent RNA Polymerase; Serine; Threonine; Transfection; Vesicular stomatitis Indiana virus; Vesiculovirus; Viral Proteins; Viral Structural Proteins | 1995 |
Isoproterenol inhibits insulin-stimulated tyrosine phosphorylation of the insulin receptor without increasing its serine/threonine phosphorylation.
Topics: Adenosine Triphosphate; Adipocytes; Adrenergic beta-Agonists; Animals; Cells, Cultured; Female; Hydrogen-Ion Concentration; Insulin; Insulin Antagonists; Isoproterenol; Peptide Mapping; Phosphorylation; Rats; Rats, Wistar; Receptor, Insulin; Serine; Threonine; Tyrosine | 1995 |
A novel serine/threonine-specific protein phosphotransferase activity of Nm23/nucleoside-diphosphate kinase.
Topics: Amino Acids; Binding Sites; Humans; Kinetics; Monomeric GTP-Binding Proteins; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phosphorylation; Phosphotransferases; Serine; Threonine; Transcription Factors; Tumor Cells, Cultured; Urea | 1995 |
Site-directed mutagenesis of Thermus thermophilus EF-Tu: the substitution of threonine-62 by serine or alanine.
Topics: Alanine; Base Sequence; Binding Sites; DNA Primers; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; RNA, Transfer, Amino Acyl; Serine; Thermus thermophilus; Threonine | 1995 |
High expression of membrane cofactor protein of complement (CD46) in human leukaemia cell lines: implication of an alternatively spliced form containing the STA domain in CD46 up-regulation.
Topics: Alternative Splicing; Amino Acid Sequence; Antibodies; Antibody Specificity; Antigens, CD; B-Lymphocytes; Base Sequence; Complement Inactivator Proteins; DNA Primers; Flow Cytometry; Humans; Leukemia; Membrane Cofactor Protein; Membrane Glycoproteins; Molecular Sequence Data; Receptors, Virus; Serine; T-Lymphocytes; Threonine; Tumor Cells, Cultured; Up-Regulation | 1995 |
Investigation of the active site of oligosaccharyltransferase from pig liver using synthetic tripeptides as tools.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Catalysis; Chemical Phenomena; Chemistry, Physical; Glycosylation; Hexosyltransferases; Hydrogen Bonding; Hydrogen-Ion Concentration; Liver; Membrane Proteins; Molecular Conformation; Molecular Sequence Data; Peptides; Serine; Structure-Activity Relationship; Substrate Specificity; Swine; Threonine; Transferases | 1995 |
Synthesis of peptide amides using Fmoc-based solid-phase procedures on 4-methylbenzhydrylamine resins.
Topics: Amides; Amino Acid Sequence; Benzhydryl Compounds; Chromatography, High Pressure Liquid; Mesylates; Molecular Sequence Data; Peptide Fragments; Peptides; Serine; Threonine | 1995 |
Cell cycle-dependent phosphorylation and microtubule binding of tau protein stably transfected into Chinese hamster ovary cells.
Topics: Animals; Cell Cycle; CHO Cells; Cricetinae; Humans; Microtubules; Mitosis; Phosphorylation; Proline; Protein Binding; Serine; tau Proteins; Threonine; Transfection | 1995 |
Identification of the major site of rat prolactin phosphorylation as serine 177.
Topics: Amino Acid Sequence; Animals; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Female; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Pituitary Gland, Anterior; Prolactin; Rats; Serine; Substrate Specificity; Threonine | 1996 |
Identification of important regions in the cytoplasmic juxtamembrane domain of type I receptor that separate signaling pathways of transforming growth factor-beta.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Division; Cells, Cultured; Cytoplasm; DNA Primers; Epithelial Cells; Epithelium; Lung; Mink; Molecular Sequence Data; Mutagenesis; Phosphorylation; Receptors, Transforming Growth Factor beta; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta | 1996 |
Analysis of serine/threonine-linked oligosaccharides derived by alkaline-borohydride treatment of mucin glycoproteins electroblotted onto membranes: comparison of the saccharide profiles of the 390 kDa and 350 kDa forms of epitectin.
Topics: alpha-Fetoproteins; Antigens, Tumor-Associated, Carbohydrate; Borohydrides; Carbohydrate Sequence; Cell Line; Chromatography, Gel; Electrochemistry; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Laryngeal Neoplasms; Molecular Sequence Data; Molecular Weight; Mucins; Oligosaccharides; Serine; Threonine; Tumor Cells, Cultured | 1995 |
Picogram detection levels of asialofetuin via the carbohydrate moieties using the light addressable potentiometric sensor.
Topics: alpha-Fetoproteins; Animals; Asialoglycoproteins; Biotin; Carbohydrate Conformation; Carbohydrate Sequence; Cattle; Fetuins; Fluoresceins; Light; Microchemistry; Molecular Sequence Data; Oligosaccharides; Potentiometry; Ricin; Serine; Threonine | 1995 |
Oral tolerance in experimental autoimmune encephalomyelitis: specificity of peptide-induced oral tolerance.
Topics: Administration, Oral; Animals; Antigens; Encephalomyelitis, Autoimmune, Experimental; Female; Freund's Adjuvant; Genetic Variation; Guinea Pigs; Immune Tolerance; Myelin Basic Protein; Peptide Fragments; Rats; Rats, Inbred Lew; Serine; Threonine | 1996 |
Dietary crude protein increases slightly the requirement for threonine in kittens.
Topics: Amino Acids; Animals; Cats; Dietary Proteins; Dose-Response Relationship, Drug; Eating; Female; Male; Nitrogen; Nutritional Requirements; Serine; Specific Pathogen-Free Organisms; Threonine; Weight Gain | 1996 |
Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A.
Topics: Alzheimer Disease; Amino Acid Sequence; Antibodies; Autoradiography; Blotting, Western; Cells, Cultured; Colchicine; Electrophoresis, Polyacrylamide Gel; Epitopes; Humans; Methionine; Microtubules; Neurons; Nocodazole; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Protein Phosphatase 2; Serine; Sulfur Radioisotopes; tau Proteins; Teratocarcinoma; Threonine; Tumor Cells, Cultured | 1996 |
Pest sequences in EF-hand calcium-binding proteins.
Topics: Amino Acid Sequence; Calcium-Binding Proteins; Glutamic Acid; Helix-Loop-Helix Motifs; Molecular Sequence Data; Multigene Family; Proline; S100 Proteins; Serine; Threonine | 1995 |
Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cloning, Molecular; Enzyme Inhibitors; Ethers, Cyclic; Flavonoids; Humans; Insulin; Insulin Receptor Substrate Proteins; Molecular Sequence Data; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Rats; Recombinant Proteins; Serine; Threonine; Transfection | 1996 |
Complex alternative RNA processing generates an unexpected diversity of poly(A) polymerase isoforms.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Baculoviridae; Base Sequence; Binding Sites; Brain; Cattle; DNA Primers; Exons; Gene Library; HeLa Cells; Humans; Isoenzymes; Mice; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Polynucleotide Adenylyltransferase; Recombinant Proteins; RNA, Messenger; Serine; Spodoptera; Threonine; Transfection; Xenopus | 1996 |
Sensitivity of HIV-1 to neutralization by antibodies against O-linked carbohydrate epitopes despite deletion of O-glycosylation signals in the V3 loop.
Topics: Amino Acid Sequence; Cloning, Molecular; Enzyme-Linked Immunosorbent Assay; Epitopes; Glycosylation; HIV Antibodies; HIV Envelope Protein gp120; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Neutralization Tests; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Sensitivity and Specificity; Sequence Deletion; Serine; Threonine | 1996 |
Identification of insulin-stimulated phosphorylation sites on calmodulin.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calmodulin; Casein Kinase II; CHO Cells; Cricetinae; Humans; In Vitro Techniques; Insulin; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Receptor, Insulin; Recombinant Proteins; Serine; Threonine; Tyrosine | 1996 |
Translation of Ser16 and Thr17 phosphorylation of phospholamban into Ca 2+-pump stimulation.
Topics: Aniline Compounds; Animals; Biological Transport, Active; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Calmodulin; Cattle; Cyclic AMP-Dependent Protein Kinases; Dogs; Fluorescent Dyes; Kinetics; Male; Myocardium; Phosphorylation; Sarcoplasmic Reticulum; Serine; Testis; Threonine; Xanthenes | 1996 |
Substrates containing phosphorylated residues adjacent to proline decrease the cleavage by proline-specific peptidases.
Topics: Amino Acid Sequence; Anilides; Aniline Compounds; Animals; Dipeptides; Endopeptidases; Flavobacterium; Humans; Hydrolysis; Kinetics; Molecular Conformation; Molecular Sequence Data; Oligopeptides; Phosphorylation; Proline; Prolyl Oligopeptidases; Protease Inhibitors; Serine; Serine Endopeptidases; Substrate Specificity; Swine; Threonine; Tyrosine | 1996 |
Architecture of the neuronal nicotinic acetylcholine receptor ion channel at the binding site of bis-ammonium blockers.
Topics: Amino Acid Sequence; Animals; Binding Sites; Bis-Trimethylammonium Compounds; Cats; Chickens; Guinea Pigs; Ileum; Ion Channels; Mice; Models, Molecular; Molecular Sequence Data; Nerve Tissue Proteins; Protein Conformation; Quaternary Ammonium Compounds; Receptors, Nicotinic; Serine; Structure-Activity Relationship; Superior Cervical Ganglion; Threonine; Torpedo | 1996 |
Is the NAD(P)H:flavin oxidoreductase from Escherichia coli a member of the ferredoxin-NADP+ reductase family?. Evidence for the catalytic role of serine 49 residue.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Catalysis; DNA Primers; Escherichia coli; Flavins; FMN Reductase; Hydroxyl Radical; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; NADP; Sequence Alignment; Serine; Threonine | 1996 |
Rebalancing essential amino acids intake by self-selection in the rat.
Topics: Amino Acids; Animals; Dietary Proteins; Food Preferences; Isoleucine; Male; Rats; Rats, Wistar; Serine; Threonine | 1996 |
Polymerization degree of oligomethionine to determine its bioavailability when added to a low-protein diets.
Topics: Animals; Biological Availability; Caseins; Catalysis; Diet, Protein-Restricted; Digestion; Eating; Liver; Male; Methionine; Organ Size; Papain; Polymers; Rats; Rats, Sprague-Dawley; Serine; Threonine; Triglycerides | 1996 |
Analysis of phosphorylation and mutation of tyrosine residues of calmodulin on its activation of the erythrocyte Ca(2+)-transporting ATPase.
Topics: Animals; Calcium-Transporting ATPases; Calmodulin; Enzyme Activation; Erythrocyte Membrane; Humans; Mutation; Phosphorylation; Serine; Swine; Threonine; Tyrosine | 1996 |
Substitution of serine or threonine at position 473 of tissue-type plasminogen activator increases its stability in plasma.
Topics: Amino Acid Sequence; Enzyme Stability; Humans; Kinetics; Metabolic Clearance Rate; Molecular Sequence Data; Mutagenesis; Serine; Threonine; Tissue Plasminogen Activator | 1996 |
Formation and activation by phosphorylation of activin receptor complexes.
Topics: Activin Receptors; Activin Receptors, Type I; Activins; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA Primers; Growth Substances; Inhibins; Kinetics; Luciferases; Methionine; Mice; Mink; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Polymerase Chain Reaction; Receptors, Growth Factor; Recombinant Proteins; Sequence Tagged Sites; Serine; Signal Transduction; Threonine | 1996 |
Selective detection and site-analysis of O-GlcNAc-modified glycopeptides by beta-elimination and tandem electrospray mass spectrometry.
Topics: Acetylglucosamine; Amino Acid Sequence; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Glycopeptides; Glycosylation; Mass Spectrometry; Molecular Sequence Data; Oligosaccharides; Serine; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship; Threonine | 1996 |
Accumulation of unphosphorylated calponin in the submembranous cytoskeletons of arachidonic acid-stimulated human platelets.
Topics: Actins; Arachidonic Acid; Calcium-Binding Proteins; Calponins; Cytoskeletal Proteins; Humans; Microfilament Proteins; Microscopy, Fluorescence; Muscle Proteins; Phosphorylation; Phosphotyrosine; Platelet Activation; Protein Binding; Serine; Stimulation, Chemical; Threonine | 1996 |
Reciprocal modulation of ATP-sensitive K+ channel activity in rat ventricular myocytes by phosphorylation of tyrosine and serine/threonine residues.
Topics: Adenosine Triphosphate; Animals; Myocardium; Phosphorylation; Potassium Channels; Rats; Rats, Sprague-Dawley; Serine; Threonine; Time Factors; Tyrosine | 1996 |
Intramolecular interactions regulate serine/threonine phosphorylation of vinculin.
Topics: Amino Acid Sequence; Animals; Gizzard, Avian; Homeostasis; Molecular Weight; Muscle, Smooth; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase C; Serine; Threonine; Turkeys; Vinculin | 1996 |
Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; DNA Primers; ErbB Receptors; GRB2 Adaptor Protein; Guanine Nucleotide Exchange Factors; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phosphopeptides; Phosphorylation; Point Mutation; Proteins; ras Guanine Nucleotide Exchange Factors; Recombinant Proteins; Sequence Tagged Sites; Serine; Threonine; Transfection | 1996 |
A postmortem study of glycine and its potential precursors in chronic schizophrenics.
Topics: Adult; Aged; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Female; Glycine; Humans; Indicators and Reagents; Male; Middle Aged; p-Dimethylaminoazobenzene; Postmortem Changes; Schizophrenia; Serine; Threonine | 1996 |
Cha4p of Saccharomyces cerevisiae activates transcription via serine/threonine response elements.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; DNA-Binding Proteins; DNA, Fungal; Gene Expression Regulation, Fungal; Molecular Sequence Data; Mutagenesis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Serine; Threonine; Trans-Activators; Transcriptional Activation; Zinc Fingers | 1996 |
Two independent domains of hDlg are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domain.
Topics: Alternative Splicing; Animals; Cytoskeletal Proteins; Cytoskeleton; Drosophila Proteins; Erythrocyte Membrane; Genes, Tumor Suppressor; Humans; Insect Hormones; Membrane Proteins; Molecular Sequence Data; Neuropeptides; Phosphoproteins; Protein Binding; Protein Conformation; Protein Sorting Signals; Protein Structure, Tertiary; Rabbits; Sequence Homology, Amino Acid; Serine; Subcellular Fractions; Threonine; Tumor Suppressor Proteins; Valine | 1996 |
The synaptic protein UNC-18 is phosphorylated by protein kinase C.
Topics: Amino Acid Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Helminth Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Serine; Synapses; Threonine; Vesicular Transport Proteins | 1996 |
Tyrosine phosphorylation of GSalpha and inhibition of bradykinin-induced activation of the cyclic AMP pathway in A431 cells by epidermal growth factor receptor.
Topics: Adenylyl Cyclases; Bradykinin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Humans; Isoproterenol; Oncogene Proteins; Phosphorylation; Serine; Threonine; Tumor Cells, Cultured; Tyrosine | 1996 |
Serine/threonine dephosphorylation may be involved in tyrosine phosphorylation: a new mode of signal transduction in platelets.
Topics: Blood Platelets; Humans; Okadaic Acid; Phosphorylation; Platelet Aggregation; Serine; Signal Transduction; Threonine; Tyrosine | 1996 |
Prediction of O-glycosylation of mammalian proteins: specificity patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase.
Topics: Algorithms; Animals; Computer Communication Networks; Glycoproteins; Glycosylation; Information Systems; Mammals; Molecular Sequence Data; N-Acetylgalactosaminyltransferases; Neural Networks, Computer; Polypeptide N-acetylgalactosaminyltransferase; Protein Structure, Secondary; Serine; Threonine | 1995 |
Casein kinase 2 phosphorylates recombinant human spermidine/spermine N1-acetyltransferase on both serine and threonine residues.
Topics: Acetyltransferases; Binding Sites; Casein Kinase II; Erythrocytes; Humans; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Substrate Specificity; Threonine | 1996 |
Phosphorylation by a G protein-coupled kinase inhibits signaling and promotes internalization of the monocyte chemoattractant protein-1 receptor. Critical role of carboxyl-tail serines/threonines in receptor function.
Topics: Amino Acid Sequence; beta-Adrenergic Receptor Kinases; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Receptors, CCR2; Receptors, Chemokine; Receptors, Cytokine; Recombinant Fusion Proteins; Serine; Signal Transduction; Structure-Activity Relationship; Threonine; Tumor Cells, Cultured | 1996 |
Structure-function relationships among wild-type variants of Staphylococcus aureus beta-lactamase: importance of amino acids 128 and 216.
Topics: Alanine; Asparagine; beta-Lactamases; Crystallography, X-Ray; Gene Expression; Genetic Variation; Kinetics; Serine; Staphylococcus aureus; Structure-Activity Relationship; Threonine | 1996 |
Multiple in vivo phosphorylated tyrosine phosphatase SHP-2 engages binding to Grb2 via tyrosine 584.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cell Line; Electrophoresis, Gel, Two-Dimensional; ErbB Receptors; GRB2 Adaptor Protein; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Mutagenesis; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Rabbits; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains; Threonine; Tyrosine | 1996 |
Immunodetection of phosphorylation sites gives new insights into the mechanisms underlying phospholamban phosphorylation in the intact heart.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Isoproterenol; Male; Myocardium; Okadaic Acid; Phosphorylation; Rats; Rats, Wistar; Serine; Threonine | 1996 |
The inhibitory effect of staurosporine on insulin action is prevented by okadaic acid. Evidence for an important role of serine/threonine phosphorylation in eliciting insulin-like effects.
Topics: Animals; Biological Transport; Enzyme Activation; Enzyme Inhibitors; Glucose; Insulin; Insulin Antagonists; Male; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Protein Phosphatase 1; Rats; Receptor, Insulin; Serine; Staurosporine; Threonine; Tyrosine | 1996 |
Glycogen synthase kinase 3 phosphorylation of different residues in the presence of different factors: analysis on tau protein.
Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Casein Kinase II; CDC2 Protein Kinase; Dichlororibofuranosylbenzimidazole; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Heparin; Molecular Sequence Data; Peptides; Phosphorylation; Proline; Protein Kinases; Protein Serine-Threonine Kinases; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Substrate Specificity; tau Proteins; Threonine | 1996 |
Mechanism of activation of protein kinase B by insulin and IGF-1.
Topics: Amino Acid Sequence; Animals; Cell Line; Enzyme Activation; Humans; Insulin; Insulin-Like Growth Factor I; Kinetics; L Cells; Mice; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Serine; Threonine; Transfection | 1996 |
Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms.
Topics: Animals; Binding Sites; Casein Kinase II; Cell Line; Consensus Sequence; Dimerization; Gene Expression; Glycosylation; HeLa Cells; Herpesvirus 3, Human; Humans; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Fc; Recombinant Fusion Proteins; Serine; Spodoptera; Threonine; Tyrosine; Viral Envelope Proteins | 1997 |
The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines.
Topics: Animals; Cell Line; Cytomegalovirus; Ganciclovir; Glutathione Transferase; Humans; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Serine-Threonine Kinases; Rabbits; Recombinant Fusion Proteins; Sequence Deletion; Serine; Spodoptera; Threonine | 1997 |
Identification of potential tyrosine-containing endocytic motifs in the carboxyl-tail and seventh transmembrane domain of the neurokinin 1 receptor.
Topics: Amino Acid Sequence; Animals; Endocytosis; Fluorescent Antibody Technique, Indirect; Microscopy, Confocal; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Neurokinin-1; Serine; Threonine; Tyrosine | 1997 |
Identification of Ser-1275 and Ser-1309 as autophosphorylation sites of the insulin receptor.
Topics: Amino Acid Sequence; Animals; Cell Line; Humans; Molecular Sequence Data; Mutation; Peptide Mapping; Phosphopeptides; Phosphorylation; Receptor, Insulin; Recombinant Proteins; Serine; Solubility; Spodoptera; Threonine | 1997 |
Identification of Ser-Pro and Thr-Pro phosphorylation sites in chicken neurofilament-M tail domain.
Topics: Amino Acid Sequence; Animals; Brain Chemistry; Chick Embryo; Chickens; Electrophoresis, Polyacrylamide Gel; Mass Spectrometry; Metalloendopeptidases; Molecular Sequence Data; Neurofilament Proteins; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphorus Radioisotopes; Phosphorylation; Proline; Protein Structure, Tertiary; Serine; Threonine | 1997 |
Angiotensin II stimulates phosphorylation of the translational repressor 4E-binding protein 1 by a mitogen-activated protein kinase-independent mechanism.
Topics: Angiotensin II; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cells, Cultured; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Rats; Serine; Threonine | 1997 |
Differential surface expression and phosphorylation of the N-methyl-D-aspartate receptor subunits NR1 and NR2 in cultured hippocampal neurons.
Topics: Animals; Cell Membrane; Cells, Cultured; Female; Hippocampus; Neurons; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Threonine; Tyrosine | 1997 |
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated
Topics: Acetaldehyde; Acrolein; Aldehydes; Amino Acids; Catalase; Chlorides; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Heme; Humans; Hydrogen Peroxide; Hydroxy Acids; Hypochlorous Acid; Inflammation; Lysine; Mass Spectrometry; Molecular Structure; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Serine; Threonine | 1997 |
Dual phosphorylation of the T-loop in cdk7: its role in controlling cyclin H binding and CAK activity.
Topics: Animals; CDC2-CDC28 Kinases; Chromatography, Gel; Cyclin H; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Models, Molecular; Molecular Weight; Mutagenesis, Site-Directed; Oocytes; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Rabbits; Serine; Structure-Activity Relationship; Threonine; Xenopus; Xenopus Proteins | 1997 |
Serine/threonine protein phosphatases and a protein phosphatase 1 inhibitor from Neurospora crassa.
Topics: Animals; Chromatography; Neurospora crassa; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Rats; Serine; Substrate Specificity; Threonine | 1996 |
Tyrosine phosphorylation of measles virus P-phosphoprotein in persistently infected neuroblastoma cells.
Topics: Animals; CSK Tyrosine-Protein Kinase; Measles virus; Mice; Neuroblastoma; Phosphoproteins; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Serine; src-Family Kinases; Threonine; Tumor Cells, Cultured; Tyrosine; Viral Proteins; Virus Latency | 1996 |
Combinatorial synthesis and biological evaluation of library of small-molecule Ser/Thr-protein phosphatase inhibitors.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Drug Design; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Marine Toxins; Mass Spectrometry; Oxazoles; Phosphoprotein Phosphatases; Serine; Threonine; Tumor Cells, Cultured | 1997 |
Bond-specific chemical cleavages of peptides and proteins with perfluoric acid vapors: novel peptide bond cleavages of glycyl-threonine, the amino side of serine residues and the carboxyl side of aspartic acid residues.
Topics: Amino Acid Sequence; Aspartic Acid; Fluorocarbons; Glycine; Molecular Sequence Data; Peptides; Proline; Proteins; Serine; Threonine | 1997 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
Mitosis-specific phosphorylation of smooth muscle regulatory light chain of myosin II at Ser-1 and/or -2 and Thr-9 in sea urchin egg extract.
Topics: 4-Butyrolactone; Animals; Binding Sites; Cell Cycle; Chickens; Enzyme Inhibitors; Gizzard, Avian; Metaphase; Mitosis; Muscle, Smooth; Myosin Light Chains; Myosin-Light-Chain Kinase; Ovum; Phosphorylation; Protein Kinase C; Sea Urchins; Serine; Threonine | 1996 |
Stress-activated protein kinase/c-jun N-terminal kinase phosphorylates tau protein.
Topics: Antibody Specificity; Blotting, Western; Brain Chemistry; Cyclic AMP-Dependent Protein Kinases; Epitopes; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Serine; Stress, Physiological; tau Proteins; Threonine | 1997 |
The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Antibodies; Brain; Cells, Cultured; Cytoplasm; HeLa Cells; Humans; Molecular Sequence Data; PC12 Cells; Phosphorylation; Rats; Serine; Threonine | 1997 |
Determination of the site-specific O-glycosylation pattern of the porcine submaxillary mucin tandem repeat glycopeptide. Model proposed for the polypeptide:galnac transferase peptide binding site.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbohydrate Sequence; Chromatography, Gel; Chromatography, High Pressure Liquid; Glycopeptides; Glycosylation; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mucins; N-Acetylgalactosaminyltransferases; Peptide Mapping; Repetitive Sequences, Nucleic Acid; Serine; Submandibular Gland; Swine; Threonine | 1997 |
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Animals; Apoptosis; Cell Line; Chromatography, Affinity; Chromatography, Ion Exchange; Enzyme Activation; Female; Humans; Kinetics; Molecular Sequence Data; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rabbits; Recombinant Fusion Proteins; Serine; Substrate Specificity; Threonine; Transfection | 1997 |
Identification of protein kinase C phosphorylation sites on bovine rhodopsin.
Topics: Amino Acid Sequence; Animals; Cattle; Eye Proteins; G-Protein-Coupled Receptor Kinase 1; Isoenzymes; Kinetics; Models, Structural; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinases; Protein Structure, Secondary; Recombinant Proteins; Retina; Rhodopsin; Serine; Spodoptera; Substrate Specificity; Threonine; Transfection | 1997 |
A mitosis-specific phosphorylation of the gap junction protein connexin43 in human vascular cells: biochemical characterization and localization.
Topics: Animals; Cell Division; Cells, Cultured; Connexin 43; Endothelium, Vascular; Gap Junctions; Humans; Mitosis; Muscle, Smooth, Vascular; Phosphorylation; Rats; Serine; Threonine; Umbilical Veins | 1997 |
On-membrane deblocking of proteins.
Topics: Formates; Membranes, Artificial; Polyvinyls; Protein Processing, Post-Translational; Proteins; Pyrrolidonecarboxylic Acid; Sequence Analysis; Serine; Threonine | 1997 |
Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; COS Cells; DNA Primers; Genes, Dominant; Genes, MHC Class II; GTP-Binding Proteins; Humans; Mutagenesis, Site-Directed; Nuclear Proteins; Oligopeptides; Peptides; Proline; Promoter Regions, Genetic; Sequence Deletion; Serine; Threonine; Trans-Activators; Transfection; Tumor Cells, Cultured | 1997 |
Regulation of N-linked core glycosylation: use of a site-directed mutagenesis approach to identify Asn-Xaa-Ser/Thr sequons that are poor oligosaccharide acceptors.
Topics: Amino Acids; Antigens, Viral; Asparagine; Binding Sites; Glutamine; Glycoproteins; Glycosylation; Mutagenesis, Site-Directed; Oligosaccharides; Rabies virus; Serine; Structure-Activity Relationship; Threonine; Viral Envelope Proteins | 1997 |
Dietary protein and amino acid levels alter threonine dehydrogenase activity in hepatic mitochondria of Gallus domesticus.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Chickens; Dietary Proteins; Eating; Enzyme Activation; Female; Food Deprivation; Glycine; Liver; Male; Mitochondria, Liver; Serine; Threonine | 1997 |
Rhodopsin phosphorylation sites and their role in arrestin binding.
Topics: Alanine; Amino Acid Sequence; Animals; Arrestin; Binding Sites; Cattle; Cell Line; Eye Proteins; G-Protein-Coupled Receptor Kinase 1; Humans; Kinetics; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Protein Kinases; Protein Structure, Secondary; Recombinant Proteins; Rhodopsin; Serine; Threonine; Transfection | 1997 |
The type II transforming growth factor-beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues.
Topics: Adenosine Triphosphate; Animals; Baculoviridae; Cloning, Molecular; Escherichia coli; Humans; Luciferases; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Serine; Spodoptera; Threonine; Transfection; Tyrosine | 1997 |
A single serine residue at position 375 of VP16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase II.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Casein Kinase II; Consensus Sequence; COS Cells; DNA-Binding Proteins; Glutamic Acid; HeLa Cells; Herpes Simplex Virus Protein Vmw65; Host Cell Factor C1; Humans; Macromolecular Substances; Molecular Sequence Data; Octamer Transcription Factor-1; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Transcription Factors; Transcriptional Activation | 1997 |
Microdialysis of human breast tissue during the menstrual cycle.
Topics: Adipose Tissue; Adult; Amino Acids; Asparagine; Aspartic Acid; Breast; Chromatography, High Pressure Liquid; Female; Glycine; Humans; Lactic Acid; Menstrual Cycle; Microdialysis; Ornithine; Pyruvic Acid; Serine; Threonine; Tyrosine | 1997 |
Design of a leucine zipper coiled coil stabilized 1.4 kcal mol-1 by phosphorylation of a serine in the e position.
Topics: Amino Acid Sequence; Arginine; Avian Proteins; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Centrifugation, Isopycnic; Circular Dichroism; Cyclic AMP-Dependent Protein Kinases; DNA Probes; DNA-Binding Proteins; G-Box Binding Factors; Genes, Reporter; Glutamic Acid; Glycine; Hot Temperature; Leucine Zippers; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Protein Binding; Protein Denaturation; Protein Engineering; Protein Structure, Secondary; Recombinant Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation; Transfection | 1997 |
Transcriptional regulation of Sertoli cell immediate early genes by interleukin-6 and interferon-gamma is mediated through phosphorylation of STAT-3 and STAT-1 proteins.
Topics: Animals; Antineoplastic Agents; DNA; DNA-Binding Proteins; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; Genistein; Interferon-gamma; Interleukin-6; Isoflavones; Male; Models, Molecular; Phosphorylation; Rats; Rats, Sprague-Dawley; RNA; Serine; Sertoli Cells; STAT1 Transcription Factor; STAT3 Transcription Factor; Threonine; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Tyrosine | 1997 |
Expression and functional analysis of a hyperglycosylated glucoamylase in a parental host, Aspergillus awamori var. kawachi.
Topics: Aspergillus; Chromosome Mapping; Cloning, Molecular; Gene Expression Regulation, Fungal; Glucan 1,4-alpha-Glucosidase; Mutagenesis; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Recombination, Genetic; Sequence Deletion; Serine; Threonine; Zea mays | 1997 |
Selective destruction of stable microtubules and axons by inhibitors of protein serine/threonine phosphatases in cultured human neurons.
Topics: Axons; Enzyme Inhibitors; Humans; Marine Toxins; Microtubules; Neurons; Okadaic Acid; Oxazoles; Serine; Threonine; Tumor Cells, Cultured | 1997 |
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays | 1997 |
Induction of prostaglandin endoperoxide synthase-2 by serine-threonine phosphatase inhibition.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Induction; Female; Isoenzymes; Mice; Mice, Inbred C57BL; NF-kappa B; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; RNA, Messenger; Serine; Threonine; Transcription Factor RelB; Transcription Factors | 1997 |
Engineering of porcine pepsin. Alteration of S1 substrate specificity of pepsin to those of fungal aspartic proteinases by site-directed mutagenesis.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Aspartic Acid Endopeptidases; Cattle; Fungal Proteins; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Pepsin A; Protein Engineering; Protein Structure, Secondary; Recombinant Proteins; Serine; Substrate Specificity; Swine; Threonine | 1997 |
Alterations in the insulin signaling pathway induced by immortalization and H-ras transformation of brown adipocytes.
Topics: Adipocytes; Adipose Tissue, Brown; Alkaline Phosphatase; Animals; Blotting, Western; Cell Line, Transformed; Dose-Response Relationship, Drug; Fetus; Guanosine Triphosphate; Insulin; Insulin Resistance; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Receptor, Insulin; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection | 1997 |
ppt-1, a Neurospora crassa PPT/PP5 subfamily serine/threonine protein phosphatase.
Topics: Amino Acid Sequence; Base Sequence; DNA, Complementary; Molecular Sequence Data; Neurospora crassa; Phosphoprotein Phosphatases; Serine; Threonine | 1997 |
Mutagenesis of two N-terminal Thr and five Ser residues in HslV, the proteolytic component of the ATP-dependent HslVU protease.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; ATP-Dependent Proteases; Dimerization; Endopeptidases; Escherichia coli; Heat-Shock Proteins; Hydrolysis; Mutagenesis, Site-Directed; Peptides; Serine; Serine Endopeptidases; Structure-Activity Relationship; Threonine | 1997 |
Phosphorylation sites in polyomavirus large T antigen that regulate its function in viral, but not cellular, DNA synthesis.
Topics: 3T3 Cells; Animals; Antigens, Polyomavirus Transforming; Binding Sites; CDC2 Protein Kinase; DNA; DNA, Viral; Humans; Mice; Mutagenesis; Phosphorylation; Polyomavirus; Recombinant Fusion Proteins; Serine; Spodoptera; Threonine; Tumor Cells, Cultured; Virus Replication | 1997 |
Colchicine activates actin polymerization by microtubule depolymerization.
Topics: 3T3 Cells; Actins; Animals; Biopolymers; Cell Line; Colchicine; Enzyme Activation; Enzyme Inhibitors; Marine Toxins; Mice; Microtubules; Okadaic Acid; Oxazoles; Phospholipase D; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Rats; Serine; Threonine; Type C Phospholipases | 1997 |
Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli.
Topics: Alanine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Glucose; Macromolecular Substances; Mutagenesis, Site-Directed; NAD; Serine; Substrate Specificity; Threonine; UDPglucose 4-Epimerase; Uridine Diphosphate; Valine | 1997 |
In vitro 14C-amino acid fermentation by CF3, a characterized continuous-flow competitive exclusion culture of caecal bacteria.
Topics: Animals; Arginine; Aspartic Acid; Carbon Radioisotopes; Cecum; Culture Media; Fermentation; Hydrogen-Ion Concentration; Poultry; Salmonella; Serine; Threonine | 1997 |
In vivo evidence for the link between L- and D-serine metabolism in rat cerebral cortex.
Topics: Amino Acids; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Glycine; Kinetics; Male; Mammals; Rats; Rats, Wistar; Serine; Stereoisomerism; Threonine; Time Factors | 1997 |
Site-directed mutagenesis of maize recombinant C4-pyruvate,orthophosphate dikinase at the phosphorylatable target threonine residue.
Topics: Adenosine Diphosphate; Aspartic Acid; Histidine; Mutagenesis, Site-Directed; Phosphorylation; Pyruvate, Orthophosphate Dikinase; Serine; Threonine; Valine; Zea mays | 1997 |
Phosphorylation site mutations in the human multidrug transporter modulate its drug-stimulated ATPase activity.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Baculoviridae; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Enzyme Activation; Humans; Mutation; Phosphorylation; Recombinant Proteins; Rhodamines; Serine; Spodoptera; Threonine; Vanadates; Verapamil; Vinblastine | 1997 |
Maintenance threonine requirement and efficiency of its use for accretion of whole-body threonine and protein in young chicks.
Topics: Analysis of Variance; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cystine; Energy Intake; Glycine; Male; Nutritional Requirements; Proline; Proteins; Regression Analysis; Serine; Threonine; Weight Gain | 1997 |
Phosphorylation of four amino acid residues in the carboxyl terminus of the rat somatostatin receptor subtype 3 is crucial for its desensitization and internalization.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; DNA, Complementary; Endocytosis; Fluorescein-5-isothiocyanate; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Rats; Receptors, Somatostatin; Serine; Threonine; Transferrin | 1997 |
Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Transformed; DNA Mutational Analysis; Exons; Female; Genes, Dominant; Glutamic Acid; Glycine; Hedgehog Proteins; Holoprosencephaly; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Threonine; Trans-Activators; Valine | 1997 |
Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail.
Topics: Alanine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Point Mutation; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 1997 |
Phosphorylation of the Src substrate Sam68 by Cdc2 during mitosis.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; CDC2 Protein Kinase; Cell Cycle; Cell Extracts; Cyclin B; DNA-Binding Proteins; Enzyme Inhibitors; HeLa Cells; Humans; Interphase; Kinetin; Mice; Mitosis; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Purines; Recombinant Proteins; RNA-Binding Proteins; Serine; Threonine | 1997 |
The conserved serine-threonine-serine motif of the carnitine acyltransferases is involved in carnitine binding and transition-state stabilization: a site-directed mutagenesis study.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Carnitine Acyltransferases; Catalysis; Cattle; Conserved Sequence; Enzyme Stability; Escherichia coli; Humans; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Recombinant Proteins; Serine; Threonine | 1997 |
Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Calpain; CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Primers; Glutamic Acid; Humans; Interleukin-2; Ionomycin; Lymphocyte Activation; Macromolecular Substances; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Cytokine; Recombinant Proteins; Sequence Alignment; Serine; Signal Transduction; Substrate Specificity; T-Lymphocytes; Threonine | 1997 |
Adult vitelliform macular dystrophy is frequently associated with mutations in the peripherin/RDS gene.
Topics: Aged; Female; Glycine; Humans; Intermediate Filament Proteins; Macular Degeneration; Male; Membrane Glycoproteins; Methionine; Middle Aged; Mutation; Nerve Tissue Proteins; Peripherins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Serine; Threonine; Tryptophan; Valine | 1997 |
O-Glycosylation of C-terminal tandem-repeated sequences regulates the secretion of rat pancreatic bile salt-dependent lipase.
Topics: Amino Acid Sequence; Animals; Brefeldin A; CHO Cells; Cricetinae; Cyclopentanes; DNA Probes; Galactose; Glutamic Acid; Glycosylation; Kinetics; Lipase; Monensin; Pancreas; Peptide Fragments; Proline; Rats; Recombinant Proteins; Serine; Sterol Esterase; Threonine; Transfection | 1997 |
Agonist-induced signaling and trafficking of the mu-opioid receptor: role of serine and threonine residues in the third cytoplasmic loop and C-terminal domain.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Etorphine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Morphine; Mutagenesis, Site-Directed; Receptors, Opioid, mu; Serine; Signal Transduction; Threonine | 1997 |
Processing of mammalian and plant S-adenosylmethionine decarboxylase proenzymes.
Topics: Adenosylmethionine Decarboxylase; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Enzyme Precursors; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Putrescine; Pyruvic Acid; Serine; Solanum tuberosum; Structure-Activity Relationship; Threonine | 1997 |
The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells.
Topics: Animals; Asparagine; Cell Line; Cell Polarity; Cytoplasm; Dogs; Glycosylation; Humans; Polysaccharides; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Recombinant Proteins; Serine; Solubility; Structure-Activity Relationship; Threonine; Transfection | 1997 |
Role of translocation in the activation and function of protein kinase B.
Topics: Amino Acid Substitution; Biological Transport; Cell Membrane; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Humans; Insulin-Like Growth Factor I; Morpholines; Phosphorylation; Protein Serine-Threonine Kinases; Protein Sorting Signals; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Threonine | 1997 |
Dephosphorylation of the cadherin-associated p100/p120 proteins in response to activation of protein kinase C in epithelial cells.
Topics: Animals; Cadherins; Carrier Proteins; Catenins; Cell Adhesion Molecules; Delta Catenin; Dogs; Enzyme Activation; Epithelial Cells; Models, Chemical; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Serine; Threonine | 1997 |
A diminished role for hydrogen bonds in antifreeze protein binding to ice.
Topics: Amino Acid Sequence; Animals; Antifreeze Proteins; Centrifugation, Isopycnic; Circular Dichroism; Flounder; Freezing; Glycoproteins; Hydrogen Bonding; Ice; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Serine; Threonine; Valine | 1997 |
The universal stress protein, UspA, of Escherichia coli is phosphorylated in response to stasis.
Topics: Amino Acid Sequence; Bacterial Proteins; Escherichia coli; Heat-Shock Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Serine; Threonine; Transcription, Genetic; Tyrosine | 1997 |
The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus.
Topics: Amino Acid Sequence; Animals; Antibodies; Binding Sites; Carrier Proteins; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Polyenes; Proline; Rats; Serine; Sirolimus; Substrate Specificity; Threonine | 1997 |
Myosin light chain-activating phosphorylation sites are required for oogenesis in Drosophila.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line, Transformed; Drosophila; Female; Gene Deletion; Glutamic Acid; Insect Proteins; Molecular Sequence Data; Myosin Light Chains; Oogenesis; Ovum; Phosphorylation; Serine; Threonine | 1997 |
Serine-294 and threonine-295 in the exofacial loop domain between helices 7 and 8 of glucose transporters (GLUT) are involved in the conformational alterations during the transport process.
Topics: Alanine; Amino Acid Sequence; Animals; Biological Transport; COS Cells; Glucose Transporter Type 4; Glycine; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Protein Conformation; Sequence Homology, Amino Acid; Serine; Threonine | 1998 |
In vitro phosphorylation of acetylcholinesterase at non-consensus protein kinase A sites enhances the rate of acetylcholine hydrolysis.
Topics: Acetylcholine; Acetylcholinesterase; Acetylthiocholine; Animals; Brain; Cattle; Cloning, Molecular; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; Erythrocytes; Escherichia coli; Humans; Hydrolysis; Kinetics; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; Serine; Threonine | 1997 |
3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Animals; Cell Line, Transformed; CHO Cells; Cricetinae; Enzyme Activation; Glutathione Transferase; Humans; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Ribosomal Protein S6 Kinases; Serine; Threonine; Transfection | 1998 |
Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tetradecanoylphorbol Acetate; Threonine | 1998 |
Cysteine 195 has a critical functional role in catalysis by isocitrate lyase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Escherichia coli; Glycine; Isocitrate Lyase; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Sequence Alignment; Sequence Analysis; Sequence Homology, Amino Acid; Serine; Threonine; Valine | 1997 |
Characterization and determination of human urinary keratan sulfate.
Topics: Carbohydrates; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Galactosamine; Humans; Keratan Sulfate; Magnetic Resonance Spectroscopy; Molecular Weight; Polysaccharides; Serine; Threonine | 1998 |
A method for the identification of promoters recognized by RNA polymerase containing a particular sigma factor: cloning of a developmentally regulated promoter and corresponding gene directed by the Streptomyces aureofaciens sigma factor RpoZ.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Isoelectric Point; Molecular Sequence Data; Open Reading Frames; Promoter Regions, Genetic; Serine; Sigma Factor; Spores, Bacterial; Streptomyces aureofaciens; Threonine; Transcription, Genetic | 1998 |
Phosphorylation-dependent regulation of the guanylyl cyclase-linked natriuretic peptide receptor B: dephosphorylation is a mechanism of desensitization.
Topics: 3T3 Cells; Animals; Binding Sites; Guanylate Cyclase; In Vitro Techniques; Kinetics; Mice; Natriuretic Peptide, C-Type; Peptide Mapping; Phosphorylation; Proteins; Rats; Receptors, Atrial Natriuretic Factor; Serine; Threonine; Trypsin | 1998 |
Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit.
Topics: Amino Acid Sequence; Animals; Catalysis; Cell Line; Enzyme Inhibitors; Enzyme Stability; Humans; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphorylation; Rabbits; Recombinant Fusion Proteins; Serine; Spodoptera; Temperature; Threonine | 1998 |
Phosphorylation of DHBV pre-S: identification of the major site of phosphorylation and effects of mutations on the virus life cycle.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Bird Diseases; Cell Line; Cells, Cultured; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Life Cycle Stages; Liver; Methionine; Molecular Sequence Data; Phosphates; Phosphorylation; Recombinant Proteins; Serine; Threonine; Transfection; Viral Envelope Proteins; Viral Proteins; Virus Replication | 1998 |
Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli.
Topics: 3T3 Cells; Animals; Cell Adhesion; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, Neurofibromatosis 2; Membrane Proteins; Mice; Neoplasm Proteins; Neurofibromin 2; Phosphorylation; Serine; Threonine; Up-Regulation | 1998 |
Sequence variation in 5' termini of rubella virus genomes: changes affecting structure of the 5' proximal stem-loop.
Topics: Amino Acid Substitution; Animals; Arginine; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; DNA, Complementary; Genes, Viral; Genetic Variation; Genome, Viral; Histidine; Lysine; Polymerase Chain Reaction; RNA, Viral; Rubella virus; Sequence Analysis, RNA; Serine; Threonine; Vero Cells | 1996 |
Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Atrial Natriuretic Factor; Binding Sites; Cell Line; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Octoxynol; Peptide Mapping; Phosphopeptides; Phosphorylation; Receptors, Atrial Natriuretic Factor; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 1998 |
ABI1 of Arabidopsis is a protein serine/threonine phosphatase highly regulated by the proton and magnesium ion concentration.
Topics: Arabidopsis; Arabidopsis Proteins; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Magnesium; Phosphoprotein Phosphatases; Plant Proteins; Protons; Serine; Threonine | 1998 |
Breaking up is easy with esters.
Topics: Cysteine; Enzyme Activation; Enzymes; Esters; Models, Chemical; Proteins; Serine; Sulfhydryl Compounds; Threonine | 1998 |
Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Antibodies, Monoclonal; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Epitopes; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphopeptides; Phosphorylation; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Serine; Substrate Specificity; tau Proteins; Threonine | 1998 |
Role of phosphorylation in determining the backbone dynamics of the serine/threonine-proline motif and Pin1 substrate recognition.
Topics: Animals; Catalysis; Cattle; Hydrogen-Ion Concentration; Isomerism; Kinetics; NIMA-Interacting Peptidylprolyl Isomerase; Oligopeptides; Osmolar Concentration; Peptidylprolyl Isomerase; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Proline; Protein Conformation; Serine; Substrate Specificity; Threonine | 1998 |
Computer modelling of dynamics of Ser92X deoxymyoglobin mutants.
Topics: Alanine; Animals; Computer Simulation; Crystallography, X-Ray; Humans; Isoleucine; Models, Molecular; Myoglobin; Point Mutation; Protein Conformation; Serine; Threonine; Valine; Whales | 1998 |
The amino acid following an asn-X-Ser/Thr sequon is an important determinant of N-linked core glycosylation efficiency.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antigens, Viral; Asparagine; Cell-Free System; Glycoproteins; Glycosylation; Mutagenesis, Site-Directed; Plasmids; Rabies virus; Serine; Threonine; Viral Envelope Proteins | 1998 |
Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components.
Topics: Alanine; Amino Acid Substitution; Animals; Annexin A5; Crystallography, X-Ray; DNA Mutational Analysis; Liposomes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Partial Thromboplastin Time; Phosphatidylcholines; Phosphatidylserines; Rats; Serine; Threonine | 1998 |
Heat stress activates fission yeast Spc1/StyI MAPK by a MEKK-independent mechanism.
Topics: Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Conserved Sequence; Enzyme Activation; Heat-Shock Response; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Osmotic Pressure; Oxidative Stress; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Serine; Signal Transduction; Threonine | 1998 |
Identification and characterization of the major phosphorylation sites of the B-type natriuretic peptide receptor.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Glycine; Guanylate Cyclase; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Receptors, Atrial Natriuretic Factor; Serine; Structure-Activity Relationship; Threonine | 1998 |
Pheromone-dependent G1 cell cycle arrest requires Far1 phosphorylation, but may not involve inhibition of Cdc28-Cln2 kinase, in vivo.
Topics: Animals; Binding Sites; CDC28 Protein Kinase, S cerevisiae; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor Proteins; Cyclins; Enzyme Inhibitors; Fungal Proteins; G1 Phase; Genes, myc; Growth Inhibitors; Histidine; Lipoproteins; Mice; Mutagenesis; Pheromones; Phosphorylation; Repressor Proteins; Saccharomyces cerevisiae Proteins; Serine; Threonine; Tripeptidyl-Peptidase 1 | 1998 |
Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Biological Transport; CHO Cells; Cricetinae; Enzyme Activation; Glucose; Glucose Transporter Type 4; Insulin; Mice; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Ribosomal Protein S6 Kinases; Serine; Threonine | 1998 |
Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Core Binding Factor Alpha 1 Subunit; COS Cells; Dimerization; DNA-Binding Proteins; Glutamine; Mice; Molecular Sequence Data; Neoplasm Proteins; Nuclear Localization Signals; Proline; Proto-Oncogene Proteins c-myc; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine; Transcription Factor AP-2; Transcription Factors; Transcriptional Activation | 1998 |
Sequence analysis of the NS5A protein of European hepatitis C virus 1b isolates and relation to interferon sensitivity.
Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Binding Sites; DNA, Viral; Europe; Genetic Variation; Hepacivirus; Hepatitis C, Chronic; Interferons; Molecular Sequence Data; Nuclear Localization Signals; Phosphorylation; Phylogeny; Protein Conformation; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Threonine; Viral Nonstructural Proteins | 1998 |
Resistance gene N-mediated de novo synthesis and activation of a tobacco mitogen-activated protein kinase by tobacco mosaic virus infection.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Induction; Mitogen-Activated Protein Kinases; Molecular Weight; Nicotiana; Plant Proteins; Plants, Toxic; Protein Kinases; RNA, Messenger; Serine; Threonine; Tobacco Mosaic Virus; Tyrosine | 1998 |
Tyrosine and tryptophan act through the same binding site at the dimer interface of yeast chorismate mutase.
Topics: Allosteric Regulation; Binding Sites; Chorismate Mutase; Codon; Dimerization; Glycine; Models, Chemical; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Serine; Threonine; Tryptophan; Tyrosine | 1998 |
Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin.
Topics: Amino Acid Sequence; Animals; Cell Adhesion; CHO Cells; Clone Cells; Cricetinae; Cytoskeletal Proteins; DNA Mutational Analysis; Fibroblasts; Fibronectins; Molecular Sequence Data; Mutagenesis, Site-Directed; Paxillin; Peptide Fragments; Phosphoproteins; Phosphorylation; Recombinant Fusion Proteins; Serine; Threonine | 1998 |
Mild cystic fibrosis mutations in Southern Sweden with special reference to S549I and T338I.
Topics: Adolescent; Adult; Age of Onset; Alleles; Amino Acid Substitution; Child; Child, Preschool; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Forced Expiratory Volume; Genotype; Humans; Infant; Isoleucine; Lung; Male; Mutation; Pancreas; Polymorphism, Genetic; Pseudomonas aeruginosa; Serine; Sweden; Threonine; Vital Capacity | 1998 |
Phosphorylation of the pheromone-responsive Gbeta protein of Saccharomyces cerevisiae does not affect its mating-specific signaling function.
Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Fungal Proteins; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein beta Subunits; GTP-Binding Proteins; Heterotrimeric GTP-Binding Proteins; Mating Factor; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Pheromones; Phosphorylation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine | 1998 |
Structure/function relationship studies on the T/S residues 173-177 of rat ODC.
Topics: Amino Acid Sequence; Animals; Conserved Sequence; DNA Mutational Analysis; Enzyme Stability; Eukaryotic Cells; Mammals; Mutation; Ornithine Decarboxylase; Peptide Fragments; Rats; Recombinant Proteins; Serine; Structure-Activity Relationship; Threonine; Trypanosoma brucei brucei | 1998 |
Occurrence of an unusual phospholipid, phosphatidyl-L-threonine, in cultured hippocampal neurons. Exogenous L-serine is required for the synthesis of neuronal phosphatidyl-L-serine and sphingolipids.
Topics: Animals; Astrocytes; Cells, Cultured; Chromatography, Thin Layer; Gangliosides; Glycerophospholipids; Hippocampus; Kinetics; Mass Spectrometry; Microsomes; Phosphatidic Acids; Phosphatidylserines; Rats; Rats, Wistar; Serine; Sphingolipids; Threonine | 1998 |
Acetyl phosphate and the phosphorylation of OmpR are involved in the regulation of the cell division rate in Escherichia coli.
Topics: Acetates; Aspartic Acid; Bacterial Proteins; Carbon; Cell Division; Culture Media; Escherichia coli; Flagella; Glutamic Acid; Models, Biological; Mutation; Organophosphates; Phosphate Acetyltransferase; Phosphorylation; Serine; Signal Transduction; Threonine; Trans-Activators | 1998 |
Frequency of the Asn-108 and Thr-108 point mutations in the dihydrofolate reductase gene in Plasmodium falciparum from southwest Colombia.
Topics: Adolescent; Adult; Animals; Asparagine; Child; Child, Preschool; Colombia; DNA, Protozoan; Female; Gene Frequency; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Serine; Tetrahydrofolate Dehydrogenase; Threonine | 1998 |
Effects of flooding amino acids on incorporation of labeled amino acids into human muscle protein.
Topics: Adult; Amino Acids; Arginine; Carbon Isotopes; Glycine; Humans; Isotope Labeling; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Serine; Threonine; Time Factors | 1998 |
Akt activation by growth factors is a multiple-step process: the role of the PH domain.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Computer Simulation; Enzyme Activation; Genetic Vectors; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Protein Conformation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Retroviridae; Sequence Alignment; Sequence Homology, Amino Acid; Serine; src Homology Domains; Threonine; Transfection | 1998 |
Dual amino acid-selective and site-directed stable-isotope labeling of the human c-Ha-Ras protein by cell-free synthesis.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Carbon Isotopes; Carbon Radioisotopes; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Humans; Isotope Labeling; Models, Chemical; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oncogene Proteins v-raf; Proline; ras Proteins; Retroviridae Proteins, Oncogenic; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine | 1998 |
Specific cleavage of amino side chains of serine and threonine in peptides and proteins with S-ethyltrifluorothioacetate vapor.
Topics: Alcohol Dehydrogenase; alpha-Endorphin; Amino Acid Sequence; Capsid; Fluoroacetates; Gases; Glucagon; Molecular Sequence Data; Mosaic Viruses; Motilin; Myoglobin; Ovalbumin; Peptide Fragments; Peptide Mapping; Peptides; Proteins; Sequence Analysis; Serine; Spectrometry, Mass, Fast Atom Bombardment; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Trifluoroacetic Acid | 1998 |
Regulation of erythroid Krüppel-like factor (EKLF) transcriptional activity by phosphorylation of a protein kinase casein kinase II site within its interaction domain.
Topics: Amino Acid Sequence; Animals; Casein Kinase II; Consensus Sequence; DNA-Binding Proteins; Globins; Kruppel-Like Transcription Factors; Leukemia, Erythroblastic, Acute; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 1998 |
Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Glycogen Synthase Kinase 3; Humans; Isomerism; Microtubule-Associated Proteins; Microtubules; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Rats; Serine; tau Proteins; Threonine | 1998 |
Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport.
Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport; Enzyme Activation; Glucose; Glucose Transporter Type 4; Insulin; Insulin Antagonists; Insulin Receptor Substrate Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Serine; Threonine; Tyrosine | 1998 |
Protein kinase activities in ripening mango, Mangifera indica L., fruit tissue. III. Purification and characterisation of a calcium-regulated protein kinase.
Topics: Adenosine Triphosphate; Calcium; Calmodulin; Caseins; Chlorpromazine; Enzyme Activation; Enzyme Inhibitors; Fruit; Histones; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Phosphorylation; Plant Proteins; Protein Kinases; Serine; Substrate Specificity; Threonine | 1998 |
Using yeast to study glucocorticoid receptor phosphorylation.
Topics: Animals; Carcinoma, Hepatocellular; Desoxycorticosterone; Dexamethasone; Gene Expression; Glucocorticoids; Mice; Peptide Mapping; Phosphoric Monoester Hydrolases; Phosphorylation; Point Mutation; Pregnatrienes; Rats; Receptors, Glucocorticoid; Saccharomyces cerevisiae; Serine; Threonine; Transcriptional Activation; Tumor Cells, Cultured | 1998 |
Microtubule-stimulated phosphorylation of tau at Ser202 and Thr205 by cdk5 decreases its microtubule nucleation activity.
Topics: Animals; Blotting, Western; Brain; Cells, Cultured; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Embryo, Mammalian; Epitopes; Humans; Kinetics; Microtubules; Neurons; Nocodazole; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Serine; Swine; tau Proteins; Threonine | 1998 |
Expression and characterization of a very low density lipoprotein receptor variant lacking the O-linked sugar region generated by alternative splicing.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Cell Line; Cricetinae; Female; Genetic Variation; Glycosylation; Humans; Male; Molecular Sequence Data; Muscle, Skeletal; Myocardium; Organ Specificity; Protein Processing, Post-Translational; Rabbits; Receptors, LDL; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Serine; Threonine; Transcription, Genetic; Transfection | 1998 |
Membrane cofactor protein: importance of N- and O-glycosylation for complement regulatory function.
Topics: Animals; Antigens, CD; Asparagine; Cell Fractionation; CHO Cells; Clone Cells; Complement Activation; Complement C3b; Complement C4b; Cricetinae; Cytoprotection; Glutamine; Glycosylation; Humans; Hydrolysis; Kinetics; Membrane Cofactor Protein; Membrane Glycoproteins; Mutagenesis, Site-Directed; Proline; Protein Structure, Tertiary; Sequence Deletion; Serine; Threonine; Transfection | 1998 |
Effect of exceptional valine replacement for highly conserved alanine-55 on the catalytic site structure of chymotrypsin-like serine protease.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cattle; Chymotrypsin; Histidine; Models, Molecular; Molecular Sequence Data; Protein C; Protein Conformation; Sequence Alignment; Serine; Threonine; Valine | 1998 |
Conformational and dynamic changes of Yersinia protein tyrosine phosphatase induced by ligand binding and active site mutation and revealed by H/D exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
Topics: Amino Acid Sequence; Binding Sites; Cyclotrons; Cysteine; Deuterium; Endopeptidases; Hydrogen; Hydrolysis; Ligands; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Conformation; Protein Tyrosine Phosphatases; Serine; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Threonine; Yersinia | 1998 |
Phosphorylation and activation of p70 S6 kinase by manganese in PC12 cells.
Topics: Animals; Anisomycin; Antibodies; Antibody Specificity; Apoptosis; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Camptothecin; Cisplatin; Cycloheximide; DNA Fragmentation; Enzyme Activation; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Manganese; Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Rats; Ribosomal Protein S6 Kinases; Serine; Staurosporine; Threonine | 1998 |
p40(phox) is phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase. Implication of a protein kinase c-type kinase in the phosphorylation process.
Topics: Amino Acid Substitution; Animals; Consensus Sequence; Enzyme Activation; HL-60 Cells; Humans; Mutagenesis, Site-Directed; NADPH Oxidases; Neutrophils; Peptide Mapping; Phagocytes; Phosphoproteins; Phosphorylation; Protein Kinase C; Rabbits; Serine; Tetradecanoylphorbol Acetate; Threonine | 1998 |
Vinculin but not alpha-actinin is a target of PKC phosphorylation during junctional assembly induced by calcium.
Topics: Actinin; Animals; Binding Sites; Calcium; Cell Line; Dogs; Microscopy, Fluorescence; Phosphorylation; Protein Kinase C; Serine; Subcellular Fractions; Threonine; Tight Junctions; Vinculin | 1998 |
Mitochondrial respiratory mutants in yeast inhibit glycogen accumulation by blocking activation of glycogen synthase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Fungal Proteins; Glucose; Glucose-6-Phosphate; Glycogen; Glycogen Synthase; Isoenzymes; Mitochondria; Molecular Sequence Data; Mutation; Oxygen Consumption; Phosphorylation; ras Proteins; Saccharomyces cerevisiae; Serine; Threonine; Ubiquinone | 1998 |
Characterization of serine and threonine phosphorylation sites in beta-elimination/ethanethiol addition-modified proteins by electrospray tandem mass spectrometry and database searching.
Topics: Amino Acid Sequence; Animals; Caseins; Cattle; Computational Biology; Databases, Factual; Electrophoresis, Polyacrylamide Gel; Humans; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Neurofilament Proteins; Phosphorylation; Sequence Alignment; Serine; Software; Sulfhydryl Compounds; Threonine | 1998 |
Heteromeric and homomeric transforming growth factor-beta receptors show distinct signaling and endocytic responses in epithelial cells.
Topics: Activin Receptors, Type I; Amino Acid Substitution; Animals; Cell Division; Cell Line; Cell Membrane; Endocytosis; Epithelial Cells; Extracellular Matrix Proteins; Kinetics; Lung; Macromolecular Substances; Mink; Mutagenesis, Site-Directed; Point Mutation; Protein Multimerization; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Transfection; Transforming Growth Factor beta | 1998 |
Determinants of strand register in antiparallel beta-sheets of proteins.
Topics: Binding Sites; Computer Simulation; Cysteine; Disulfides; Hydrogen Bonding; Isoleucine; Models, Molecular; Peptides; Proline; Protein Conformation; Protein Structure, Secondary; Serine; Threonine; Valine | 1998 |
Sodium taurocholate cotransporting polypeptide is a serine, threonine phosphoprotein and is dephosphorylated by cyclic adenosine monophosphate.
Topics: Amino Acids; Animals; Carrier Proteins; Cyclic AMP; Liver; Organic Anion Transporters, Sodium-Dependent; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Rats; Serine; Subcellular Fractions; Symporters; Threonine; Tissue Distribution | 1998 |
The requirement of phosphorylation on a threonine residue in the acute regulation of steroidogenesis in MA-10 mouse Leydig cells.
Topics: Alkaline Phosphatase; Animals; Electrophoresis, Gel, Two-Dimensional; Homoserine; Leydig Cells; Male; Mice; Mitochondria; Phosphorylation; Progesterone; Protein Synthesis Inhibitors; Proteins; Serine; Steroids; Threonine; Tumor Cells, Cultured | 1993 |
Evidence for differential binding of isoniazid by Mycobacterium tuberculosis KatG and the isoniazid-resistant mutant KatG(S315T).
Topics: Amino Acid Substitution; Bacterial Proteins; Drug Resistance, Microbial; Electron Spin Resonance Spectroscopy; Isoniazid; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Peroxidases; Protein Binding; Serine; Spectrophotometry; Threonine | 1998 |
Agonist-induced phosphorylation of the angiotensin AT1a receptor is localized to a serine/threonine-rich region of its cytoplasmic tail.
Topics: Affinity Labels; Amino Acid Sequence; Animals; COS Cells; Cytoplasm; Inositol Phosphates; Molecular Sequence Data; Phosphorylation; Point Mutation; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Serine; Threonine; Transfection | 1998 |
Direct effects of phosphorylation on the preferred backbone conformation of peptides: a nuclear magnetic resonance study.
Topics: Amino Acid Sequence; Biophysical Phenomena; Biophysics; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Oligopeptides; Phosphorylation; Protein Conformation; Serine; Threonine; Tyrosine | 1999 |
Evidence for phosphorylation of CLN3 protein associated with Batten disease.
Topics: Animals; Casein Kinase II; CHO Cells; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Green Fluorescent Proteins; Humans; Luminescent Proteins; Membrane Glycoproteins; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteins; Recombinant Fusion Proteins; Serine; Threonine | 1998 |
Varicella-zoster virus Fc receptor component gI is phosphorylated on its endodomain by a cyclin-dependent kinase.
Topics: Amino Acid Sequence; Animals; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Line, Transformed; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drosophila; Drosophila Proteins; Enzyme Inhibitors; Glutathione Transferase; HeLa Cells; Herpesvirus 3, Human; Humans; Jurkat Cells; Molecular Sequence Data; Phosphorylation; Positive Transcriptional Elongation Factor B; Proline; Protein Serine-Threonine Kinases; Purines; Receptors, Fc; Recombinant Fusion Proteins; Roscovitine; Serine; Threonine; Transfection; Tumor Cells, Cultured; Viral Envelope Proteins | 1999 |
Enhancement of cyanogen bromide cleavage yields for methionyl-serine and methionyl-threonine peptide bonds.
Topics: Chromatography, High Pressure Liquid; Cyanogen Bromide; Formates; Mass Spectrometry; Methionine; Peptides; Recombinant Proteins; Serine; Threonine; Water | 1999 |
Contribution to Tl+, K+, and Na+ binding of Asn776, Ser775, Thr774, Thr772, and Tyr771 in cytoplasmic part of fifth transmembrane segment in alpha-subunit of renal Na,K-ATPase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Binding Sites; Cytoplasm; Hydroxides; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Potassium; Protein Structure, Tertiary; Recombinant Proteins; Serine; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Thallium; Threonine; Tyrosine | 1998 |
Anti-apoptotic function of Rac in hematopoietic cells.
Topics: Animals; Apoptosis; Bone Marrow Cells; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Survival; GTP Phosphohydrolases; GTP-Binding Proteins; Mice; Mitogen-Activated Protein Kinases; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; rac GTP-Binding Proteins; Retroviridae Proteins, Oncogenic; Serine; Threonine | 1999 |
Cell-cycle-regulated phosphorylation of cAMP response element-binding protein: identification of novel phosphorylation sites.
Topics: Amino Acid Sequence; Amnion; Cell Cycle; Cell Line; Consensus Sequence; Cyclic AMP Response Element-Binding Protein; HeLa Cells; Humans; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Protein Isoforms; Serine; Threonine; Transcriptional Activation | 1999 |
CaMKII-dependent phosphorylation of NR2A and NR2B is decreased in animals characterized by hippocampal damage and impaired LTP.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Enzyme Activation; Female; Gene Expression; Hippocampus; In Situ Hybridization; Long-Term Potentiation; Methylazoxymethanol Acetate; Nerve Degeneration; Neurons; Organ Culture Techniques; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serine; Synapses; Threonine; Tyrosine | 1999 |
AMP-activated protein kinase phosphorylation of endothelial NO synthase.
Topics: Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Aorta; Calmodulin; Cattle; Endothelium, Vascular; Enzyme Activation; Kinetics; Liver; Molecular Sequence Data; Multienzyme Complexes; Myocardial Ischemia; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; Serine; Threonine | 1999 |
Serine 948 and threonine 1042 are crucial residues for allosteric regulation of Escherichia coli carbamoylphosphate synthetase and illustrate coupling effects of activation and inhibition pathways.
Topics: Allosteric Regulation; Arginine; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cloning, Molecular; DNA, Bacterial; Escherichia coli; Kinetics; Models, Molecular; Mutation; Phenotype; Protein Conformation; Serine; Threonine; Uracil | 1999 |
The nucleoprotein of Marburg virus is target for multiple cellular kinases.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Chloramphenicol O-Acetyltransferase; Gene Expression Regulation, Viral; Genes, Reporter; HeLa Cells; Humans; Marburgvirus; Molecular Sequence Data; Nucleocapsid Proteins; Nucleoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Ribonucleoproteins; RNA-Binding Proteins; Serine; Spodoptera; Threonine; Viral Proteins | 1999 |
A recurring two-hydrogen-bond motif incorporating a serine or threonine residue is found both at alpha-helical N termini and in other situations.
Topics: Amino Acid Sequence; Animals; Conserved Sequence; Databases, Factual; Hydrogen Bonding; Models, Molecular; Mutation; Protein Structure, Secondary; Proteins; Sequence Alignment; Serine; Terminology as Topic; Threonine | 1999 |
Defining the substrate specificity of cdk4 kinase-cyclin D1 complex.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Binding Sites; Conserved Sequence; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; HeLa Cells; Humans; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Serine; Substrate Specificity; Threonine | 1999 |
Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Catalytic Domain; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Inhibitors; Humans; Molecular Sequence Data; Molecular Weight; Muscle Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Phosphatase 1; Proteins; Rabbits; Serine; Threonine | 1999 |
Sialyltransferase isoforms are phosphorylated in the cis-medial Golgi on serine and threonine residues in their luminal sequences.
Topics: Animals; beta-D-Galactoside alpha 2-6-Sialyltransferase; Catalytic Domain; COS Cells; Goats; Golgi Apparatus; Ionophores; Isoenzymes; Monensin; Phosphorylation; Rabbits; Serine; Sialyltransferases; Structure-Activity Relationship; Threonine; Transfection; Tumor Cells, Cultured | 1999 |
Structural features underlying the unusual mode of calmodulin phosphorylation by protein kinase CK2: A study with synthetic calmodulin fragments.
Topics: Amino Acid Sequence; Binding Sites; Calcium; Calmodulin; Casein Kinase II; Holoenzymes; Kinetics; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Secondary; Serine; Threonine | 1999 |
Hydrogen bonds between short polar side chains and peptide backbone: prevalence in proteins and effects on helix-forming propensities.
Topics: Asparagine; Aspartic Acid; Glutamine; Hydrogen Bonding; Kinetics; Protein Structure, Secondary; Serine; Threonine | 1999 |
Rhodopsin's carboxyl-terminal threonines are required for wild-type arrestin-mediated quench of transducin activation in vitro.
Topics: Animals; Arrestin; Cattle; COS Cells; GTP-Binding Proteins; Mutation; Phosphorylation; Rhodopsin; Serine; Threonine; Transducin | 1999 |
A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Cells, Cultured; Cloning, Molecular; DNA Mutational Analysis; Humans; Mice; Molecular Sequence Data; Oncogene Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Sequence Alignment; Serine; Structure-Activity Relationship; Threonine | 1999 |
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; I-kappa B Kinase; Interleukin-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Mutagenesis; NF-kappa B; NF-kappaB-Inducing Kinase; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proteins; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; TNF Receptor-Associated Factor 6; Transfection | 1999 |
Functional analysis of O-linked oligosaccharides in threonine/serine-rich region of Aspergillus glucoamylase by expression in mannosyltransferase-disruptants of yeast.
Topics: Aspergillus; Cloning, Molecular; Enzyme Stability; Glucan 1,4-alpha-Glucosidase; Glycosylation; Mannosyltransferases; Oligosaccharides; Saccharomyces cerevisiae; Serine; Threonine; Transfection | 1999 |
Dynamic epigenetic regulation of initial O-glycosylation by UDP-N-Acetylgalactosamine:Peptide N-acetylgalactosaminyltransferases. site-specific glycosylation of MUC1 repeat peptide influences the substrate qualities at adjacent or distant Ser/Thr position
Topics: Acetylgalactosamine; Amino Acid Sequence; Animals; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Gene Expression Regulation; Glycosylation; Humans; Milk, Human; Molecular Sequence Data; Mucin-1; N-Acetylgalactosaminyltransferases; Peptide Fragments; Polypeptide N-acetylgalactosaminyltransferase; Protein Conformation; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Substrate Specificity; Threonine | 1999 |
Posttranslational modification of CLN3 protein and its possible functional implication.
Topics: Alkaline Phosphatase; Animals; Cell Membrane; CHO Cells; Cricetinae; Cyclins; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Glycoside Hydrolases; Green Fluorescent Proteins; Immunoblotting; Luminescent Proteins; Mannosephosphates; Membrane Glycoproteins; Molecular Chaperones; Phosphoamino Acids; Phosphorylation; Precipitin Tests; Protein Processing, Post-Translational; Radioisotopes; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Serine; Threonine | 1999 |
Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Base Sequence; Cell Line; DNA Primers; Enzyme Activation; Humans; Hydrogen Peroxide; Immediate-Early Proteins; Insulin-Like Growth Factor I; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Substrate Specificity; Threonine; Transfection | 1999 |
Association of polo-like kinase with alpha-, beta- and gamma-tubulins in a stable complex.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromatography, Gel; Chromatography, Ion Exchange; DNA Primers; Interphase; Mice; Mitosis; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Serine; Threonine; Tubulin; Tumor Cells, Cultured | 1999 |
Site-directed mutagenesis of phosphate-contacting amino acids of bovine pancreatic deoxyribonuclease I.
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Deoxyribonuclease I; DNA; Hydrolysis; Mutagenesis, Site-Directed; RNA, Transfer, Tyr; Serine; Substrate Specificity; Sugar Phosphates; Threonine; Thymidine; Tyrosine | 1999 |
An EXCEL-based method to search for potential Ser/Thr-phosphorylation sites in proteins.
Topics: Binding Sites; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Serine; Software; Threonine | 1999 |
SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1.
Topics: Amino Acid Sequence; Amino Acids; Animals; Base Sequence; DNA Primers; DNA-Binding Proteins; Enhancer Elements, Genetic; Mice; Mutagenesis, Site-Directed; Proline; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fes; Serine; Structure-Activity Relationship; Threonine; Trans-Activators; Transcription Factors; Transcriptional Activation | 1999 |
Bradykinin-induced internalization of the human B2 receptor requires phosphorylation of three serine and two threonine residues at its carboxyl tail.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bradykinin; Cell Line; CHO Cells; Clathrin; Coated Pits, Cell-Membrane; COS Cells; Cricetinae; DNA Primers; Endocytosis; Humans; Kinetics; Molecular Sequence Data; Phosphorylation; Receptor, Bradykinin B2; Receptors, Bradykinin; Recombinant Proteins; Serine; Threonine; Transfection | 1999 |
Phosphorylated seryl and threonyl, but not tyrosyl, residues are efficient specificity determinants for GSK-3beta and Shaggy.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Drosophila; Drosophila Proteins; Eukaryotic Initiation Factor-2B; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Guanine Nucleotide Exchange Factors; Molecular Sequence Data; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 1999 |
Structural and spectral response of green fluorescent protein variants to changes in pH.
Topics: Amino Acid Substitution; Animals; Crystallography, X-Ray; Glutamic Acid; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Luminescent Proteins; Mutagenesis, Site-Directed; Pigments, Biological; Protons; Scyphozoa; Serine; Spectrometry, Fluorescence; Structure-Activity Relationship; Threonine | 1999 |
Molecular characterisation of the defective alpha 1-antitrypsin alleles PI Mwurzburg (Pro369Ser), Mheerlen (Pro369Leu), and Q0lisbon (Thr68Ile).
Topics: Adult; Alleles; alpha 1-Antitrypsin; Animals; Child; Female; Gene Expression; Humans; Isoleucine; Leucine; Male; Mice; Pedigree; Proline; Serine; Serine Proteinase Inhibitors; Threonine | 1999 |
The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5.
Topics: Animals; Aurora Kinases; CDC2 Protein Kinase; Cell Cycle Proteins; Cells, Cultured; Kinesins; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Serine; Threonine; Xenopus laevis; Xenopus Proteins | 1999 |
Phosphorylation of the transactivation domain of Pax6 by extracellular signal-regulated kinase and p38 mitogen-activated protein kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Eye Proteins; Homeodomain Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Mutation; p38 Mitogen-Activated Protein Kinases; Paired Box Transcription Factors; PAX6 Transcription Factor; Phosphorylation; Proline; Repressor Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation; Zebrafish | 1999 |
Ser16 prevails over Thr17 phospholamban phosphorylation in the beta-adrenergic regulation of cardiac relaxation.
Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Ionophores; Isoproterenol; Myocardial Contraction; Myocardium; Organ Culture Techniques; Phosphorylation; Rats; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum; Serine; Threonine | 1999 |
Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.
Topics: Amino Acid Substitution; Androstadienes; Animals; Blood Proteins; Cell Cycle Proteins; Cells, Cultured; Consensus Sequence; Enzyme Inhibitors; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Insulin; Liver; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Simian virus 40; Structure-Activity Relationship; Threonine; Transcription Factors; Wortmannin | 1999 |
Evaluation of the roles of the conserved residues of aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amino Acid Sequence; Arginine; Binding Sites; Conserved Sequence; Glutamic Acid; Humans; Kinetics; Mutagenesis; NAD; Recombinant Fusion Proteins; Serine; Threonine | 1999 |
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Androstadienes; Antibody Specificity; bcl-Associated Death Protein; Caenorhabditis elegans Proteins; Carrier Proteins; Consensus Sequence; DNA-Binding Proteins; Enzyme Activation; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Insulin-Like Growth Factor I; Molecular Sequence Data; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Serine; Signal Transduction; Sirolimus; Threonine; Transcription Factors; Wortmannin | 1999 |
A constitutively "phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitization.
Topics: Adenine; Amino Acid Sequence; Amino Acid Substitution; Atrial Natriuretic Factor; Enzyme Inhibitors; Glutamic Acid; Guanylate Cyclase; Humans; Microcystins; Molecular Sequence Data; Mutation; Peptides, Cyclic; Phosphorylation; Receptors, Atrial Natriuretic Factor; Recombinant Proteins; Serine; Threonine | 1999 |
Human and rodent transcription elongation factor P-TEFb: interactions with human immunodeficiency virus type 1 tat and carboxy-terminal domain substrate.
Topics: Amino Acid Sequence; Animals; Cations; Cell Line; CHO Cells; Cricetinae; Cyclin T; Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinases; Cyclins; Gene Products, tat; HIV-1; Humans; Magnesium; Mice; Molecular Sequence Data; Phosphorylation; Positive Transcriptional Elongation Factor B; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; RNA Polymerase II; Rodentia; Serine; Spodoptera; Substrate Specificity; tat Gene Products, Human Immunodeficiency Virus; Threonine | 1999 |
BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site.
Topics: Binding Sites; BRCA1 Protein; CDC2-CDC28 Kinases; Cell Line, Transformed; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Humans; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Substrate Specificity; Threonine | 1999 |
Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Binding Sites; Biological Transport; Cattle; Cell Line; Cell Membrane; Enzyme Activation; Humans; Mitogens; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine; Time Factors | 1999 |
Phosphorylation and/or presence of serine 37 in the movement protein of tomato mosaic tobamovirus is essential for intracellular localization and stability in vivo.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Fluorescence; Glutamic Acid; Green Fluorescent Proteins; Intracellular Fluid; Luminescent Proteins; Molecular Sequence Data; Mutagenesis; Nicotiana; Phosphoamino Acids; Phosphorylation; Plant Viral Movement Proteins; Plants, Toxic; Protoplasts; Recombinant Fusion Proteins; Serine; Solanum lycopersicum; Threonine; Tobamovirus; Viral Proteins | 1999 |
Capillary zone electrophoresis and MALDI-mass spectrometry for the monitoring of in vitro O-glycosylation of a threonine/serine-rich MUC5AC hexadecapeptide.
Topics: Amino Acid Sequence; Electrophoresis, Capillary; Glycosylation; Humans; Molecular Sequence Data; Mucin 5AC; Mucins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 1999 |
The hydrophobic phosphorylation motif of conventional protein kinase C is regulated by autophosphorylation.
Topics: Amino Acid Sequence; Animals; COS Cells; Kinetics; Models, Biological; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Serine; Threonine; Time Factors | 1999 |
Residues phosphorylated by TFIIH are required for E2F-1 degradation during S-phase.
Topics: Amino Acid Sequence; Carrier Proteins; Cell Cycle Proteins; Cell Line; DNA-Binding Proteins; Drosophila Proteins; E2F Transcription Factors; E2F1 Transcription Factor; HeLa Cells; Humans; Hydrolysis; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Kinases; Retinoblastoma-Binding Protein 1; S Phase; Sequence Homology, Amino Acid; Serine; Threonine; Trans-Activators; Transcription Factor DP1; Transcription Factor TFIIH; Transcription Factors; Transcription Factors, TFII; Transcription, Genetic | 1999 |
Presentation of cytosolic glycosylated peptides by human class I major histocompatibility complex molecules in vivo.
Topics: Acetylglucosamine; Animals; Antigen Presentation; ATP-Binding Cassette Transporters; Chromatography, High Pressure Liquid; Cytosol; Glycosylation; Histocompatibility Antigens Class I; Humans; Mice; Protein Processing, Post-Translational; Serine; Threonine | 1999 |
Tyrosine phosphorylation of A17 during vaccinia virus infection: involvement of the H1 phosphatase and the F10 kinase.
Topics: Animals; Binding Sites; Cell Line; Chlorocebus aethiops; Dual Specificity Phosphatase 3; Escherichia coli; Membrane Proteins; Peptides; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Serine; Threonine; Tyrosine; Vaccinia virus; Viral Envelope Proteins; Viral Proteins | 1999 |
The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Precursors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Intracellular Signaling Peptides and Proteins; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Antigen, B-Cell; Serine; Signal Transduction; src-Family Kinases; Syk Kinase; Threonine; Tumor Cells, Cultured | 1999 |
Phosphorylation and activation of phospholipase D1 by protein kinase C in vivo: determination of multiple phosphorylation sites.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Chromatography, High Pressure Liquid; Enzyme Activation; Fibroblasts; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phospholipase D; Phosphopeptides; Phosphorylation; Protein Kinase C; Rats; Serine; Tetradecanoylphorbol Acetate; Threonine | 1999 |
Hydrogen bonding modulates binding of exogenous ligands in a myoglobin proximal cavity mutant.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Glycine; Histidine; Hydrogen Bonding; Imidazoles; Ligands; Macromolecular Substances; Metmyoglobin; Models, Chemical; Mutagenesis, Insertional; Myoglobin; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Protons; Serine; Threonine; Whales | 1999 |
Inhibition of dihydrofolate reductases from Toxoplasma gondii, Pneumocystis carinii, and rat liver by rotationally restricted analogues of pyrimethamine and metoprine.
Topics: Animals; Binding Sites; Computer Simulation; Folic Acid; Folic Acid Antagonists; Liver; Molecular Structure; Oxidoreductases; Pneumocystis; Pyrimethamine; Rats; Serine; Threonine; Toxoplasma | 1999 |
SH2-B, a membrane-associated adapter, is phosphorylated on multiple serines/threonines in response to nerve growth factor by kinases within the MEK/ERK cascade.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Membrane; Intracellular Signaling Peptides and Proteins; Mutagenesis, Site-Directed; Nerve Growth Factors; PC12 Cells; Phosphorylation; Rats; Serine; Tetradecanoylphorbol Acetate; Threonine | 1999 |
Characterization of RANTES- and aminooxypentane-RANTES-triggered desensitization signals reveals differences in recruitment of the G protein-coupled receptor complex.
Topics: Arrestins; beta-Adrenergic Receptor Kinases; CCR5 Receptor Antagonists; Chemokine CCL5; Clathrin; Coated Vesicles; Cyclic AMP-Dependent Protein Kinases; Desensitization, Immunologic; Down-Regulation; Dynamins; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Kinetics; Phosphorylation; Receptor Protein-Tyrosine Kinases; Receptors, CCR5; Serine; Signal Transduction; Threonine; Time Factors; Transfection | 1999 |
Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3.
Topics: Calcineurin Inhibitors; CD4-Positive T-Lymphocytes; Cell Nucleus; Cyclosporine; Cytoplasm; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Marine Toxins; Microscopy, Confocal; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Serine; Signal Transduction; STAT3 Transcription Factor; Staurosporine; Threonine; Trans-Activators; Tumor Cells, Cultured | 1999 |
Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M(1) muscarinic acetylcholine receptors.
Topics: Amino Acid Sequence; Binding, Competitive; Cell Line; Humans; Membrane Proteins; Molecular Sequence Data; Muscarinic Agonists; Mutation; Proline; Protein Conformation; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Serine; Threonine; Tyrosine | 1999 |
Voltage- and calcium-dependent inactivation of calcium channels in Lymnaea neurons.
Topics: Actins; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Chelating Agents; Cytochalasin B; Cytoplasm; Egtazic Acid; Electrophysiology; Fluorescent Dyes; Fura-2; Ion Channel Gating; Kinetics; Lymnaea; Neurons; Patch-Clamp Techniques; Phosphorylation; Serine; Threonine | 1999 |
Cysteine-rich regions of pig gastric mucin contain von willebrand factor and cystine knot domains at the carboxyl terminal(1).
Topics: Amino Acid Sequence; Animals; Base Sequence; Cysteine; Cystine; DNA, Complementary; Epithelium; Gastric Mucins; Gastric Mucosa; Hydrogen-Ion Concentration; Molecular Sequence Data; Sequence Alignment; Serine; Swine; Tandem Repeat Sequences; Threonine; von Willebrand Factor | 1999 |
Tyrosine versus serine/threonine phosphorylation by protein kinase casein kinase-2. A study with peptide substrates derived from immunophilin Fpr3.
Topics: Amino Acid Sequence; Casein Kinase II; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Fragments; Peptidylprolyl Isomerase; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Serine; Substrate Specificity; Threonine; Tyrosine | 1999 |
Partial glycosylation of Asn2181 in human factor V as a cause of molecular and functional heterogeneity. Modulation of glycosylation efficiency by mutagenesis of the consensus sequence for N-linked glycosylation.
Topics: Asparagine; Carbohydrate Conformation; Chromatography, Ion Exchange; Consensus Sequence; Factor V; Factor Va; Glycoside Hydrolases; Glycosylation; Humans; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Prothrombin Time; Recombinant Proteins; Serine; Threonine; Thrombin | 1999 |
Induction, characterisation and pathogenicity in rainbow trout Oncorhynchus mykiss (Walbaum) of Lactococcus garvieae L-forms.
Topics: Animals; Antibodies, Bacterial; Cell Culture Techniques; Cell Wall; Charcoal; Electrophoresis, Polyacrylamide Gel; Erythromycin; Fish Diseases; Fluorescent Antibody Technique, Indirect; Glycine; Gram-Positive Bacterial Infections; Lactococcus; Lysine; Microscopy, Electron; Oncorhynchus mykiss; Phenylalanine; Rabbits; Serine; Threonine | 1999 |
Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin.
Topics: Cell Adhesion; Cells, Cultured; Cortactin; Epidermal Growth Factor; Flavonoids; Humans; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Microfilament Proteins; Neoplasm Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; src Homology Domains; Structure-Activity Relationship; Threonine | 1999 |
Characterization of a Hank's type serine/threonine kinase and serine/threonine phosphoprotein phosphatase in Pseudomonas aeruginosa.
Topics: Amino Acid Sequence; Cloning, Molecular; Genes, Bacterial; Molecular Sequence Data; Multigene Family; Phosphoamino Acids; Phosphoprotein Phosphatases; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Serine; Threonine | 1999 |
The interferon-induced double-stranded RNA-activated protein kinase PKR will phosphorylate serine, threonine, or tyrosine at residue 51 in eukaryotic initiation factor 2alpha.
Topics: Alleles; Cell Line; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Humans; Isoelectric Focusing; Phosphorylation; Protein Biosynthesis; Serine; Substrate Specificity; Threonine; Tyrosine | 1999 |
Sequencing of peptides phosphorylated on serines and threonines by post-source decay in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Amino Acid Sequence; Humans; Molecular Sequence Data; Molecular Structure; Peptides; Phosphorylation; Sequence Analysis, Protein; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrometry, Mass, Secondary Ion; Threonine | 1999 |
Pyrazine formation from serine and threonine.
Topics: Flame Ionization; Food Preservation; Gas Chromatography-Mass Spectrometry; Hot Temperature; Humans; Pyrazines; Serine; Threonine | 1999 |
Characterization of the phosphorylated forms and the phosphorylated residues of hepatitis delta virus delta antigens.
Topics: Amino Acid Sequence; Electrophoresis, Gel, Two-Dimensional; Hepatitis Antigens; Hepatitis delta Antigens; Hepatitis Delta Virus; Humans; Isoelectric Point; Molecular Sequence Data; Phosphorylation; Protein Isoforms; Serine; Threonine; Tumor Cells, Cultured | 1999 |
Comparison of volatile generation in serine/threonine/glutamine-ribose/glucose/fructose model systems.
Topics: Fructose; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Ribose; Serine; Threonine; Volatilization | 1999 |
Serine/threonine protein phosphatases and regulation of K-Cl cotransport in human erythrocytes.
Topics: Anemia, Sickle Cell; Biological Transport; Carrier Proteins; Cell Size; Cytosol; Dehydration; Enzyme Inhibitors; Erythrocytes; Humans; Ionophores; K Cl- Cotransporters; Marine Toxins; Membrane Proteins; Nystatin; Okadaic Acid; Osmolar Concentration; Oxazoles; Phosphoprotein Phosphatases; Serine; Symporters; Threonine; Water-Electrolyte Balance | 1999 |
Serine/threonine phosphorylation of calmodulin modulates its interaction with the binding domains of target enzymes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amino Acid Sequence; Binding Sites; Calcium-Transporting ATPases; Calmodulin; Calmodulin-Binding Proteins; Casein Kinase II; Dansyl Compounds; Models, Molecular; Molecular Sequence Data; Myosin-Light-Chain Kinase; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Quaternary; Serine; Threonine | 1999 |
Ndr protein kinase is regulated by phosphorylation on two conserved sequence motifs.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Animals; Binding Sites; Cell Line, Transformed; Conserved Sequence; COS Cells; Humans; Mass Spectrometry; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Sequence Analysis; Sequence Homology, Amino Acid; Serine; Threonine | 1999 |
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.
Topics: Amino Acid Sequence; Apoptosis; Binding Sites; CDC2 Protein Kinase; Cyclin B; Cyclin B1; Enzyme Activation; G2 Phase; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 7; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Microtubules; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitosis; Molecular Sequence Data; Mutagenesis; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Serine; Threonine | 1999 |
Turnover rates at regulatory phosphorylation sites on myosin II in endothelial cells.
Topics: Animals; Binding Sites; Cattle; Cells, Cultured; Endothelium, Vascular; Myosin Light Chains; Myosins; Peptide Mapping; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Serine; Sulfur Radioisotopes; Threonine; Wound Healing | 1999 |
Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon.
Topics: Allosteric Regulation; Amino Acids; Cell Line; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Isoenzymes; Leucine; Morpholines; Naphthalenes; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinases; Serine; Signal Transduction; Sirolimus; Threonine; TOR Serine-Threonine Kinases; Transfection | 1999 |
Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Cell Line; Glutamic Acid; Guanylate Cyclase; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphoproteins; Phosphorylation; Receptors, Atrial Natriuretic Factor; Recombinant Proteins; Serine; Threonine | 1999 |
Sequence and structure-based prediction of eukaryotic protein phosphorylation sites.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Consensus Sequence; Eukaryotic Cells; Glycosylation; Models, Molecular; Neural Networks, Computer; Nuclear Proteins; Phosphoproteins; Phosphorylation; Phylogeny; Protein Structure, Tertiary; Reproducibility of Results; Sensitivity and Specificity; Serine; Substrate Specificity; Threonine; Trans-Activators; Tyrosine | 1999 |
Protein kinase CK1 is a p53-threonine 18 kinase which requires prior phosphorylation of serine 15.
Topics: Amino Acid Sequence; Binding Sites; Casein Kinases; DNA Damage; Glutathione Transferase; Humans; Isoenzymes; Molecular Sequence Data; Phosphorylation; Protein Kinases; Recombinant Fusion Proteins; Sequence Alignment; Serine; Substrate Specificity; Threonine; Tumor Suppressor Protein p53 | 1999 |
The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes.
Topics: Animals; Cell Membrane; Epithelial Sodium Channels; Immediate-Early Proteins; Kinetics; Nuclear Proteins; Oocytes; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; Serine; Sodium Channels; Threonine; Xenopus laevis | 1999 |
Modulation of human neutrophil responses to CD32 cross-linking by serine/threonine phosphatase inhibitors: cross-talk between serine/threonine and tyrosine phosphorylation.
Topics: Adult; Calcium; Calcium Signaling; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Marine Toxins; Neutrophil Activation; Neutrophils; Oncogene Protein v-cbl; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Receptors, IgG; Retroviridae Proteins, Oncogenic; Serine; Superoxides; Threonine; Tyrosine | 2000 |
Phosphorylation modulates the function of the vasoactive intestinal polypeptide receptor transcriptional repressor protein.
Topics: Amino Acid Sequence; Animals; Casein Kinase II; Cell Line; Consensus Sequence; COS Cells; Cyclic AMP-Dependent Protein Kinases; Mutagenesis, Site-Directed; Phosphorylation; Protein Biosynthesis; Protein Serine-Threonine Kinases; Rats; Recombinant Fusion Proteins; Recombinant Proteins; Replication Protein C; Repressor Proteins; Serine; Threonine; Transcription Factors; Transcription, Genetic; Transfection | 2000 |
Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP beta is required for hepatocyte proliferation induced by TGF alpha.
Topics: Amino Acid Sequence; Animals; CCAAT-Enhancer-Binding Proteins; Cell Division; DNA-Binding Proteins; Enzyme Activation; Female; Liver; Mice; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Threonine; Transforming Growth Factor alpha | 1999 |
14-3-3zeta interacts with the alpha-chain of human interleukin 9 receptor.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Binding Sites; Humans; Molecular Sequence Data; Phosphorylation; Precipitin Tests; Protein Isoforms; Proteins; Receptors, Interleukin; Receptors, Interleukin-9; Serine; Threonine; Two-Hybrid System Techniques; Tyrosine 3-Monooxygenase | 2000 |
Effects of glyphosate and dalapon on total free amino acid profiles of Pseudosuccinea columella snails.
Topics: Alanine; Amino Acids; Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Glyphosate; Herbicides; Propionates; Serine; Snails; Threonine | 2000 |
Inhibition of phosphatidylinositol 4,5-bisphosphate-stimulated phospholipase D2 activity by Ser/Thr phosphorylation.
Topics: Animals; COS Cells; Enzyme Inhibitors; HeLa Cells; Humans; Okadaic Acid; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphorylation; Serine; Threonine; Transfection | 2000 |
Different ocular abnormalities in individuals of a three-generation family caused by a new nonsense mutation in the PST domain of the PAX6 gene. Mutations in brief no. 189. Online.
Topics: Aniridia; Codon, Nonsense; DNA-Binding Proteins; Eye Proteins; Homeodomain Proteins; Humans; Mutation; Paired Box Transcription Factors; PAX6 Transcription Factor; Proline; Repressor Proteins; Serine; Threonine | 1998 |
Conformation of paired helical filaments blocks dephosphorylation of epitopes shared with fetal tau except Ser199/202 and Ser202/Thr205.
Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Alzheimer Disease; Amino Acid Sequence; Brain; Epitopes; Female; Fetus; Formates; Humans; Kinetics; Middle Aged; Neuropil Threads; Phosphorylation; Serine; tau Proteins; Threonine | 2000 |
Random-coil chemical shifts of phosphorylated amino acids.
Topics: Amino Acids; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorus Isotopes; Phosphorylation; Protein Structure, Secondary; Serine; Threonine; Tyrosine | 1999 |
Benzoylserine and benzoylthreonine in propionic acidaemia treated with sodium benzoate.
Topics: Amino Acid Metabolism, Inborn Errors; Female; Humans; Mass Spectrometry; Propionates; Serine; Sodium Benzoate; Threonine | 1999 |
Kv4.2 phosphorylation by cyclic AMP-dependent protein kinase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, High Pressure Liquid; COS Cells; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dose-Response Relationship, Drug; Hippocampus; Kinetics; Models, Biological; Molecular Sequence Data; Oligopeptides; Phosphorylation; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Shal Potassium Channels; Signal Transduction; Structure-Activity Relationship; Threonine; Time Factors | 2000 |
Kinetic mechanism of the p38-alpha MAP kinase: phosphoryl transfer to synthetic peptides.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; Kinetics; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Proline; Protein Binding; Pyridines; Serine; Threonine; Viscosity | 2000 |
Presence of 2-furoylmethyl derivatives in hydrolysates of processed tomato products.
Topics: Alanine; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Freeze Drying; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Hydrolysis; Lysine; Maillard Reaction; Serine; Solanum lycopersicum; Threonine | 2000 |
A cluster of Ser/Thr residues at the C-terminus of mu-opioid receptor is required for G protein-coupled receptor kinase 2-mediated desensitization.
Topics: Analgesics, Opioid; Animals; beta-Adrenergic Receptor Kinases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; G-Protein-Coupled Receptor Kinase 2; Humans; Naloxone; Narcotic Antagonists; Rats; Receptors, Opioid, mu; Serine; Threonine; Transfection | 2000 |
Glutamic acid mutagenesis of retinoblastoma protein phosphorylation sites has diverse effects on function.
Topics: Bone Neoplasms; Cell Cycle; Cell Line; Cyclin-Dependent Kinases; Genes, Retinoblastoma; Glutamic Acid; Humans; Kidney; Mutagenesis, Site-Directed; Osteosarcoma; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Retinoblastoma Protein; Serine; Structure-Activity Relationship; Threonine; Transfection; Tumor Cells, Cultured | 2000 |
Amino acid sequence of an unique ribonuclease with a C-terminus rich in O-glycosylated serine and threonine from culture medium of Lentinus edodes.
Topics: Agaricales; Amino Acid Sequence; Culture Media; Endoribonucleases; Glycosylation; Molecular Sequence Data; Ribonucleases; Serine; Threonine | 2000 |
A protein kinase activity associated with Epstein-Barr virus BGLF4 phosphorylates the viral early antigen EA-D in vitro.
Topics: Amino Acid Sequence; Antigens, Viral; Cloning, Molecular; Cytoplasm; Enzyme Inhibitors; Escherichia coli; Heparin; Herpesvirus 4, Human; Immune Sera; Kinetics; Molecular Sequence Data; Okadaic Acid; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Sequence Homology, Amino Acid; Serine; Threonine; Viral Proteins | 2000 |
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Animals; Conserved Sequence; Enzyme Activation; Mice; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2000 |
Sample optimization and identification of signal patterns of amino acid side chains in 2D RFDR spectra of the alpha-spectrin SH3 domain.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chemical Precipitation; Isoleucine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Proline; Protein Conformation; Serine; Spectrin; src Homology Domains; Threonine; Valine | 2000 |
Calf intestinal mucin: isolation, partial characterization, and measurement in ileal digesta with an enzyme-linked immunosorbent assay.
Topics: Abomasum; Animals; Antibody Specificity; Aspartic Acid; Carbohydrates; Cattle; Centrifugation, Density Gradient; Cesium; Chlorides; Diet; Digestion; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Ileum; Immune Sera; Intestines; Milk; Mucins; Serine; Threonine | 2000 |
Skeletal muscle CaMKII enriches in nuclei and phosphorylates myogenic factor SRF at multiple sites.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Chickens; DNA-Binding Proteins; Molecular Sequence Data; Muscle, Skeletal; Nuclear Proteins; Peptide Mapping; Phosphorylation; Rats; Serine; Serum Response Factor; Threonine | 2000 |
Novel rearranged ions observed for protonated peptides via metastable decomposition in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Bradykinin; Gas Chromatography-Mass Spectrometry; Oxygen Isotopes; Peptides; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2000 |
Functional role of transmembrane helix 7 in the activation of the heptahelical lutropin receptor.
Topics: Amino Acid Sequence; Animals; Asparagine; Chorionic Gonadotropin; COS Cells; Cyclic AMP; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rats; Receptors, LH; Serine; Signal Transduction; Structure-Activity Relationship; Threonine; Transfection | 2000 |
Determination of a cAMP-dependent protein kinase phosphorylation site in the C-terminal region of human endothelial actin-binding protein.
Topics: Amino Acid Motifs; Amino Acid Substitution; Blood Platelets; Calpain; Contractile Proteins; Cyclic AMP-Dependent Protein Kinases; Endothelium; Filamins; Humans; Immune Sera; Microfilament Proteins; Molecular Weight; Mutation; Peptide Fragments; Phosphorylation; Phosphoserine; Recombinant Proteins; Sequence Analysis, Protein; Serine; Threonine | 2000 |
Autophosphorylation of type I phosphatidylinositol phosphate kinase regulates its lipid kinase activity.
Topics: Animals; Cations; Cattle; COS Cells; Inositol Phosphates; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Saccharomyces cerevisiae Proteins; Serine; Spinal Cord; Threonine | 2000 |
Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression.
Topics: Amino Acids; Carrier Proteins; Eukaryotic Initiation Factor-4E; Insulin; Mutation; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Repressor Proteins; RNA Caps; Serine; Sirolimus; Threonine | 2000 |
The influenza A virus M1 protein interacts with the cellular receptor of activated C kinase (RACK) 1 and can be phosphorylated by protein kinase C.
Topics: Animals; Binding Sites; Chick Embryo; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Indoles; Influenza A virus; Ion Channels; Maleimides; Peptides; Phosphorylation; Protein Kinase C; Receptors for Activated C Kinase; Recombinant Proteins; Serine; Software; Structure-Activity Relationship; Threonine; Viral Matrix Proteins | 2000 |
Control sites of ribosomal S6 kinase B and persistent activation through tumor necrosis factor.
Topics: Amino Acid Sequence; Catalytic Domain; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; HeLa Cells; Humans; Indoles; Insulin; Ionomycin; Isoquinolines; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Substrate Specificity; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha | 2000 |
Ser/Thr phosphorylation of hematopoietic specific protein 1 (HS1): implication of protein kinase CK2.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Blood Platelets; Blood Proteins; Blotting, Western; Casein Kinase II; Enzyme Inhibitors; Humans; Kinetics; Molecular Sequence Data; Okadaic Acid; Phosphates; Phosphorylation; Polylysine; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Serine; Threonine | 2000 |
Why does threonine, and not serine, function as the active site nucleophile in proteasomes?
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cysteine Endopeptidases; Kinetics; Multienzyme Complexes; Oligopeptides; Peptide Library; Proteasome Endopeptidase Complex; Recombinant Proteins; Serine; Substrate Specificity; Thermoplasma; Threonine | 2000 |
Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures.
Topics: Amino Acids; Asparagine; Aspartic Acid; Crystallization; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Protein Conformation; Protein Structure, Secondary; Proteins; Serine; Threonine | 2000 |
Thr38 and Ser198 are Pto autophosphorylation sites required for the AvrPto-Pto-mediated hypersensitive response.
Topics: Amino Acid Sequence; Bacterial Proteins; Molecular Sequence Data; Phosphorylation; Plant Proteins; Protein Binding; Protein Serine-Threonine Kinases; Pseudomonas; Serine; Signal Transduction; Solanum lycopersicum; Threonine | 2000 |
Frequency-encoding Thr17 phospholamban phosphorylation is independent of Ser16 phosphorylation in cardiac myocytes.
Topics: Adenosine Triphosphatases; Animals; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cells, Cultured; Myocardium; Phosphorylation; Rats; Serine; Threonine | 2000 |
The amino-terminal cyclic nucleotide binding site of the type II cGMP-dependent protein kinase is essential for full cyclic nucleotide-dependent activation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cell Line; Conserved Sequence; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type II; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Isoenzymes; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Serine; Spodoptera; Threonine | 2000 |
The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR.
Topics: Animals; Cells, Cultured; eIF-2 Kinase; Enzyme Activation; Eukaryotic Initiation Factor-4E; Humans; Isoelectric Point; Mice; Mice, Inbred C57BL; Peptide Initiation Factors; Phosphoprotein Phosphatases; Phosphorylation; Precipitin Tests; Protein Phosphatase 2; Serine; Substrate Specificity; Threonine; Transfection; Two-Hybrid System Techniques | 2000 |
Functional characteristics of insulin receptors with a Thr-->Ser1200 mutation overexpressed in Chinese hamster ovary cells.
Topics: Alkaline Phosphatase; Animals; CHO Cells; Cricetinae; Enzyme Activation; Gene Expression; Humans; Insulin; Insulin-Like Growth Factor I; Mutation; Phosphorylation; Protein Kinases; Receptor, Insulin; Serine; Swine; Threonine; Transfection | 2000 |
Dual regulation of platelet protein kinase B.
Topics: Blood Platelets; Humans; In Vitro Techniques; Indomethacin; Isoenzymes; Kinetics; Phosphatidylinositol 3-Kinases; Phospholipase C beta; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Serine; Threonine; Thrombin; Type C Phospholipases | 2000 |
Evidence for phosphorylation and ubiquitinylation of the turnip yellow mosaic virus RNA-dependent RNA polymerase domain expressed in a baculovirus-insect cell system.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Baculoviridae; Cells, Cultured; Insecta; Molecular Sequence Data; Molecular Weight; Phosphorylation; Recombinant Proteins; RNA-Dependent RNA Polymerase; Sequence Homology, Amino Acid; Serine; Threonine; Tymovirus; Ubiquitins | 2000 |
Specific Ser-Pro phosphorylation by the RNA-recognition motif containing kinase KIS.
Topics: Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; DNA, Complementary; Escherichia coli; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Myelin Basic Protein; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; RNA; Sequence Analysis, Protein; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Synapsins; Threonine; Time Factors | 2000 |
Towards models of vanadate-dependent haloperoxidases: the hydroxyl side chain.
Topics: Binding Sites; Cysteine; Homoserine; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Structure; Peroxidases; Protein Tyrosine Phosphatases; Serine; Threonine; Tyrosine; Vanadates | 2000 |
Prolonged stationary-phase incubation selects for lrp mutations in Escherichia coli K-12.
Topics: Alanine; Alleles; Bacterial Proteins; Carbon; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Leucine; Leucine-Responsive Regulatory Protein; Mutation; Phenotype; Selection, Genetic; Serine; Threonine; Time Factors; Transcription Factors | 2000 |
The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Antigens, CD; Carrier Proteins; CD79 Antigens; Cytoplasm; Enzyme Inhibitors; Humans; Immunoglobulin Fragments; Immunoglobulin Variable Region; Molecular Sequence Data; Phosphoproteins; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Receptors, Antigen, B-Cell; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
The Mycobacterium bovis homologous protein of the Mycobacterium tuberculosis serine/threonine protein kinase Mbk (PknD) is truncated.
Topics: Animals; Bacterial Outer Membrane Proteins; Blotting, Western; Cloning, Molecular; Immune Sera; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mycobacterium bovis; Mycobacterium tuberculosis; Open Reading Frames; Polymerase Chain Reaction; Protein Kinases; Sequence Homology, Nucleic Acid; Serine; Threonine | 2000 |
Differences in the post-translational modifications of human papillomavirus type 6b major capsid protein expressed from a baculovirus system compared with a vaccinia virus system.
Topics: Animals; Baculoviridae; Capsid; Electrophoresis, Gel, Two-Dimensional; Fatty Acids; Glycosylation; Papillomaviridae; Phosphorylation; Protein Engineering; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Threonine; Vaccinia virus | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Inhibition of Akt and its anti-apoptotic activities by tumor necrosis factor-induced protein kinase C-related kinase 2 (PRK2) cleavage.
Topics: Animals; Apoptosis; Caspases; Cell Line; Epidermal Growth Factor; Humans; Hydrolysis; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Threonine; Tumor Necrosis Factor-alpha; Two-Hybrid System Techniques | 2000 |
The effects of changing the site of activating phosphorylation in CDK2 from threonine to serine.
Topics: Amino Acid Substitution; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Humans; Kinetics; Mutagenesis, Site-Directed; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Substrate Specificity; Threonine | 2000 |
Spectroscopic comparison of the heme active sites in WT KatG and its S315T mutant.
Topics: Bacterial Proteins; Binding Sites; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Heme; Hemeproteins; Histidine; Ligands; Mutation; Mycobacterium tuberculosis; Peroxidases; Recombinant Proteins; Serine; Spectrum Analysis, Raman; Threonine | 2000 |
Serine 121 is an essential amino acid for biotin sulfoxide reductase functionality.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Binding Sites; Biotin; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; Conserved Sequence; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Factor Xa; Glutathione Transferase; Guanine Nucleotides; Iron-Sulfur Proteins; Ligands; Mass Spectrometry; Metalloproteins; Molecular Sequence Data; Molybdenum Cofactors; Mutagenesis, Site-Directed; NADP; Oxidative Stress; Oxidoreductases; Oxygen; Paraquat; Pteridines; Pterins; Recombinant Fusion Proteins; Rhodobacter sphaeroides; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors | 2000 |
Recombinant expression and modification analysis of protein agno-1b encoded by avian polyomavirus BFDV.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Chick Embryo; Endopeptidases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Polyomavirus; Protein Processing, Post-Translational; Recombination, Genetic; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Viral Proteins; Viral Regulatory and Accessory Proteins | 2000 |
A family of secreted mucins from the parasitic nematode Toxocara canis bears diverse mucin domains but shares similar flanking six-cysteine repeat motifs.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Chromatography; Chromatography, High Pressure Liquid; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Expressed Sequence Tags; Female; Gastric Mucins; Gene Library; Models, Biological; Models, Molecular; Molecular Sequence Data; Mucins; Multigene Family; Protein Sorting Signals; Protein Structure, Tertiary; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Toxocara canis | 2000 |
The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Casein Kinases; Catalytic Domain; Cell Nucleus; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Recombinant Fusion Proteins; Serine; Substrate Specificity; Threonine; Transcription Factors; Tumor Suppressor Protein p53; Viral Proteins | 2000 |
Hierarchical phosphorylation of delta-opioid receptor regulates agonist-induced receptor desensitization and internalization.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line; Enkephalin, D-Penicillamine (2,5)-; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Receptors, Opioid, delta; Serine; Structure-Activity Relationship; Threonine | 2000 |
Protein phosphatase 2A is associated with class C L-type calcium channels (Cav1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase.
Topics: Amino Acids; Animals; Brain; Calcium Channels, L-Type; Catalytic Domain; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Escherichia coli; Glutathione Transferase; Humans; Immunoblotting; Inhibitory Concentration 50; Ionophores; Microcystins; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Phosphatase 2; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Serine; Threonine | 2000 |
Redox potential measurements of the Mycobacterium tuberculosis heme protein KatG and the isoniazid-resistant enzyme KatG(S315T): insights into isoniazid activation.
Topics: Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; Drug Resistance, Microbial; Enzyme Activation; Free Radicals; Hemeproteins; Isoniazid; Mycobacterium tuberculosis; Oxidation-Reduction; Peroxidases; Potentiometry; Serine; Sodium Cyanide; Spectrophotometry; Threonine | 2000 |
Melatonin-induced organelle movement in melanophores is coupled to tyrosine phosphorylation of a high molecular weight protein.
Topics: Adenylate Cyclase Toxin; Animals; Blotting, Western; Cell Aggregation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Genistein; GTP-Binding Proteins; Kinetics; Melanophores; Melatonin; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine; Virulence Factors, Bordetella; Xenopus | 2000 |
Regulation of plasmodesmal transport by phosphorylation of tobacco mosaic virus cell-to-cell movement protein.
Topics: Amino Acids; Biological Transport; Calcium Chloride; Cell Communication; Cell Wall; Dextrans; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Magnesium Chloride; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Nicotiana; Phosphorylation; Plant Viral Movement Proteins; Plants, Genetically Modified; Plants, Toxic; Protein Binding; RNA; Serine; Threonine; Tobacco Mosaic Virus; Viral Proteins | 2000 |
Amino acid selectivity in the aminoacylation of coenzyme A and RNA minihelices by aminoacyl-tRNA synthetases.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Chromatography, Thin Layer; Coenzyme A; Electrophoresis; Escherichia coli; Evolution, Molecular; Isoleucine-tRNA Ligase; Kinetics; Leucine; Lysine-tRNA Ligase; RNA; Serine; Threonine; Time Factors; Valine; Valine-tRNA Ligase | 2000 |
Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells.
Topics: 3T3 Cells; Androstadienes; Animals; Apoptosis; Blotting, Western; Cell Line; Cells, Cultured; Cerebellum; Cerebral Cortex; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Insulin-Like Growth Factor I; Mice; Mutagenesis; Myristic Acid; Nerve Tissue Proteins; Neurons; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Serine; Sirolimus; Threonine; Transcription Factors; Transfection; Vanadates; Wortmannin | 2000 |
Casein kinase II phosphorylation of caldesmon downregulates myosin-caldesmon interactions.
Topics: Animals; Binding Sites; Calmodulin-Binding Proteins; Casein Kinase II; Chickens; Down-Regulation; Muscle, Smooth; Mutagenesis, Site-Directed; Myosins; Phosphorylation; Point Mutation; Protein Binding; Protein Serine-Threonine Kinases; Sequence Deletion; Serine; Structure-Activity Relationship; Threonine | 2000 |
Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Base Sequence; Catalysis; Cell Membrane; Ceramides; CHO Cells; Cricetinae; DNA Primers; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine | 2000 |
Ciprofibrate stimulates protein kinase C-dependent phosphorylation of an 85 kDa protein in rat Fao hepatic derived cells.
Topics: Animals; Cell Line; Clofibric Acid; Fibric Acids; Liver; Molecular Weight; Peroxisome Proliferators; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Serine; Substrate Specificity; Threonine | 2000 |
DNA repair protein O6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Casein Kinase II; Cations; Chromatography, Agarose; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Genistein; Guanosine Triphosphate; Humans; Magnesium; Manganese; Medulloblastoma; Mice; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Phosphates; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Threonine; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2000 |
Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of Fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein.
Topics: Calcium-Binding Proteins; Child, Preschool; Cyclic AMP-Dependent Protein Kinases; Epinephrine; Female; GTP-Binding Protein alpha Subunits, Gs; Guanosine Triphosphate; Heart Ventricles; Humans; Infant; Male; Myocardial Contraction; Myocardium; Phosphorylation; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Serine; Tetralogy of Fallot; Threonine; Troponin I | 2000 |
PKC and ERK1/2 regulate amylase promoter activity during differentiation of a salivary gland cell line.
Topics: Amylases; Calcium; Cell Adhesion; Cell Differentiation; Cell Line; Collagen; Drug Combinations; Drug Synergism; Humans; Integrins; Intracellular Membranes; Isoenzymes; Laminin; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Protein Serine-Threonine Kinases; Proteoglycans; Serine; Submandibular Gland; Threonine; Transforming Growth Factor alpha | 2000 |
Transforming growth factor beta inhibits the phosphorylation of pRB at multiple serine/threonine sites and differentially regulates the formation of pRB family-E2F complexes in human myeloid leukemia cells.
Topics: Blotting, Western; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line; DNA; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; E2F3 Transcription Factor; E2F4 Transcription Factor; Gene Expression Regulation; Humans; Leukemia, Myeloid; Macromolecular Substances; Myeloid Cells; Nuclear Proteins; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Proteins; Retinoblastoma Protein; Retinoblastoma-Binding Protein 1; Retinoblastoma-Like Protein p107; Retinoblastoma-Like Protein p130; Serine; Threonine; Time Factors; Transcription Factor DP1; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured | 2000 |
Recombinant brassinosteroid insensitive 1 receptor-like kinase autophosphorylates on serine and threonine residues and phosphorylates a conserved peptide motif in vitro.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Molecular Sequence Data; Phosphorylation; Phytosterols; Protein Kinases; Recombinant Proteins; Serine; Signal Transduction; Threonine | 2000 |
Association between mutations of the follicle-stimulating-hormone receptor and repeated twinning.
Topics: Adenine; Adult; Alanine; Asparagine; Codon; Exons; Female; Genetic Linkage; Guanine; Humans; Phenotype; Point Mutation; Receptors, FSH; Serine; Threonine; Twins, Dizygotic | 2000 |
p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 3; MAP Kinase Kinase 6; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositols; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Serine; Threonine | 2001 |
Crystal structures of cytochrome P450nor and its mutants (Ser286-->Val, Thr) in the ferric resting state at cryogenic temperature: a comparative analysis with monooxygenase cytochrome P450s.
Topics: Binding Sites; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Electrons; Fusarium; Heme; Hydrogen Bonding; Kinetics; Ligands; Models, Molecular; Mutation; Nitric Oxide; Oxidoreductases; Protein Conformation; Protein Structure, Secondary; Protons; Recombinant Proteins; Serine; Spectrophotometry; Temperature; Threonine; Valine; Water | 2000 |
Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins.
Topics: Actin Cytoskeleton; Adult; Amino Acid Sequence; Amino Acid Substitution; Glutamic Acid; Humans; Microtubules; Molecular Mimicry; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Polymerase Chain Reaction; Protein Conformation; Protein Phosphatase 2; Serine; Structure-Activity Relationship; tau Proteins; Threonine | 2000 |
Serine and threonine residues bend alpha-helices in the chi(1) = g(-) conformation.
Topics: Animals; Biophysical Phenomena; Biophysics; Cattle; GTP-Binding Proteins; In Vitro Techniques; Membrane Proteins; Models, Molecular; Protein Conformation; Protein Structure, Secondary; Proteins; Receptors, Cell Surface; Serine; Threonine | 2000 |
Changes in protein kinase C epsilon phosphorylation status and intracellular localization as 3T3 and 3T6 fibroblasts grow to confluency and quiescence: a role for phosphorylation at ser-729?
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Blotting, Western; Cell Adhesion; Cell Division; Cell Line; Cell Nucleus; Culture Media; Cytosol; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Golgi Apparatus; Isoenzymes; Mice; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-epsilon; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2000 |
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7.
Topics: Animals; Cell Line; Cloning, Molecular; Enzyme Activation; Humans; Insecta; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Kinase 7; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Osmosis; Peptide Mapping; Phosphorylation; Protein Isoforms; Serine; Substrate Specificity; Threonine; Trypsin; Tyrosine | 2000 |
Identification of the bile acid-binding site of the ileal lipid-binding protein by photoaffinity labeling, matrix-assisted laser desorption ionization-mass spectrometry, and NMR structure.
Topics: Amino Acid Sequence; Animals; Arginine; Bile Acids and Salts; Binding Sites; Carrier Proteins; Cholagogues and Choleretics; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Immunoblotting; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Organic Anion Transporters, Sodium-Dependent; Phenylglyoxal; Photoaffinity Labels; Protein Binding; Rabbits; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Symporters; Taurocholic Acid; Threonine | 2001 |
Phosphorylation status of the parvovirus minute virus of mice particle: mapping and biological relevance of the major phosphorylation sites.
Topics: Animals; Capsid; Capsid Proteins; Cell Line; Humans; Mice; Minute Virus of Mice; Phosphorylation; Protein Processing, Post-Translational; Serine; Threonine | 2000 |
8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chickens; CREB-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Histone Acetyltransferases; Mitogen-Activated Protein Kinases; Models, Genetic; Nuclear Proteins; Nuclear Receptor Coactivator 1; Peptide Mapping; Phosphopeptides; Phosphorylation; Progesterone; Protein Binding; Receptors, Progesterone; Recombinant Proteins; Serine; Signal Transduction; Threonine; Trans-Activators; Transcription Factors; Transcriptional Activation | 2000 |
The two major plant plasma membrane H+-ATPases display different regulatory properties.
Topics: 14-3-3 Proteins; Adenosine Triphosphatases; Amino Acid Sequence; Binding Sites; Blotting, Western; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Histidine; Molecular Sequence Data; Multigene Family; Mutation; Nicotiana; Phosphorylation; Plant Proteins; Plants; Plants, Toxic; Plasmids; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Proton-Translocating ATPases; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Serine; Threonine; Tyrosine 3-Monooxygenase | 2001 |
Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: role of the carboxyl terminus in EP4 receptor sequestration.
Topics: Amino Acid Sequence; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Microscopy, Confocal; Molecular Sequence Data; Protein Structure, Tertiary; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Serine; Threonine | 2000 |
p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation.
Topics: Animals; Anisomycin; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Northern; Cell Nucleus; COS Cells; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Gamma Rays; Glutathione Transferase; Humans; Hydrogen Peroxide; Imidazoles; Luciferases; Methyl Methanesulfonate; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Proteins; Plasmids; Precipitin Tests; Pyridines; Recombinant Fusion Proteins; Serine; Serine Proteinase Inhibitors; Signal Transduction; Threonine; Time Factors; Transfection; Tumor Suppressor Protein p53; Ultraviolet Rays | 2000 |
Phosphorylation of phospholamban at threonine-17 in the absence and presence of beta-adrenergic stimulation in neonatal rat cardiomyocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Animals, Newborn; Blotting, Western; Calcium; Calcium Channel Agonists; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ionophores; Isoproterenol; Myocardium; Okadaic Acid; Phosphorylation; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Serine; Signal Transduction; Thapsigargin; Threonine; Time Factors | 2000 |
Utilizing the peptidyl-prolyl cis-trans isomerase pin1 as a probe of its phosphorylated target proteins. Examples of binding to nuclear proteins in a human kidney cell line and to tau in Alzheimer's diseased brain.
Topics: Alzheimer Disease; Brain; Cell Line; Cell Nucleus; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Kidney; Male; Middle Aged; Mitosis; Molecular Probes; NIMA-Interacting Peptidylprolyl Isomerase; Nocodazole; Nuclear Proteins; Peptidylprolyl Isomerase; Phosphorylation; Protein Binding; Serine; tau Proteins; Threonine | 2001 |
Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adipocytes; Animals; beta-Cyclodextrins; Carcinogens; Caveolae; Cell Differentiation; Cell Division; Cell Membrane; Cells, Cultured; Cholesterol; Cyclodextrins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glucose; Immunoblotting; Immunohistochemistry; Insulin; Insulin Receptor Substrate Proteins; MAP Kinase Signaling System; Mice; Microscopy, Electron; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Threonine; Time Factors; Tyrosine | 2001 |
Requirements and effects of palmitoylation of rat PLD1.
Topics: Animals; Base Sequence; Brain; Catalysis; COS Cells; DNA Primers; Mutagenesis, Site-Directed; Palmitic Acid; Phospholipase D; Phosphorylation; Rats; Serine; Threonine | 2001 |
Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.
Topics: Alanine; Alleles; Bacteriophages; Base Sequence; Cell Division; Chromatography, Gel; Cloning, Molecular; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; Genetic Complementation Test; Kinetics; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Sequence Homology, Nucleic Acid; Serine; Threonine; Thymidine; Time Factors; Viral Proteins | 2001 |
Kinase suppressor of Ras signals through Thr269 of c-Raf-1.
Topics: Animals; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Humans; Mice; Mutation; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins c-raf; ras Proteins; Recombinant Proteins; Serine; Signal Transduction; Threonine; Transfection; Tyrosine; Valine | 2001 |
Transfer RNA-mediated editing in threonyl-tRNA synthetase. The class II solution to the double discrimination problem.
Topics: Acylation; Binding Sites; Crystallography, X-Ray; Kinetics; Models, Molecular; Mutation; Nucleic Acid Conformation; Protein Structure, Tertiary; RNA Editing; RNA, Transfer, Amino Acyl; Serine; Threonine; Threonine-tRNA Ligase; Transfer RNA Aminoacylation; Zinc | 2000 |
Citrullinemia type II in a 64-year-old man with fluctuating serum citrulline levels.
Topics: Ammonia; Biomarkers; Brain; Cerebrovascular Circulation; Citrulline; Citrullinemia; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Serine; Threonine; Trypsin Inhibitor, Kazal Pancreatic | 2001 |
The ribosomal binding and peptidyl-tRNA hydrolysis functions of Escherichia coli release factor 2 are linked through residue 246.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Codon; Escherichia coli; Hydrolysis; Molecular Sequence Data; Mutagenesis; Peptide Chain Termination, Translational; Peptide Termination Factors; Phenotype; Protein Conformation; Recombinant Fusion Proteins; RNA, Transfer, Amino Acyl; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine | 2000 |
Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation.
Topics: 3T3 Cells; Androstadienes; Animals; Cysteine Endopeptidases; Enzyme Inhibitors; Insulin; Insulin Receptor Substrate Proteins; Mice; Multienzyme Complexes; Okadaic Acid; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Serine; Sirolimus; Threonine; Time Factors; Tyrosine; Vanadates; Wortmannin | 2001 |
Phosphorylation down-regulates the RNA binding function of the coat protein of potato virus A.
Topics: Binding, Competitive; Cadmium; Calcium; Capsid; Dose-Response Relationship, Drug; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Immunoblotting; Kinetics; Magnesium; Magnetics; Manganese; Nicotiana; Phosphorylation; Plant Viruses; Plants, Toxic; Plasmids; Recombinant Fusion Proteins; RNA; RNA-Binding Proteins; Serine; Staurosporine; Threonine; Tobacco Mosaic Virus; Trypsin; Zinc | 2001 |
Database analysis of O-glycosylation sites in proteins.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Biophysical Phenomena; Biophysics; Databases, Factual; Glycosylation; Mucins; Proline; Proteins; Serine; Threonine | 2001 |
Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain.
Topics: Animals; Cells, Cultured; Chromatography, Gel; Cytoplasm; Dimerization; Disulfides; Humans; Insecta; Phosphorylation; Plasma; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rabbits; Receptor, IGF Type 1; Serine; Threonine | 2000 |
Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells.
Topics: Androstadienes; Blotting, Western; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Marine Toxins; Okadaic Acid; Oxazoles; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Serine; Sphingosine; Threonine; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Wortmannin | 2001 |
Protein control of the redox potential of the primary quinone acceptor in reactioncCenters from Rhodobacter sphaeroides.
Topics: Amino Acid Substitution; Binding Sites; Electron Transport; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Mutagenesis, Site-Directed; Naphthoquinones; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Quinones; Rhodobacter sphaeroides; Serine; Threonine; Ubiquinone | 2001 |
Tyrosine phosphorylation of p120(ctn) in v-Src transfected L cells depends on its association with E-cadherin and reduces adhesion activity.
Topics: Amino Acid Substitution; Animals; Base Sequence; Cadherins; Catenins; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Delta Catenin; DNA Primers; Mice; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Serine; Threonine; Tyrosine | 2001 |
Inhibition of PP-2A upregulates CaMKII in rat forebrain and induces hyperphosphorylation of tau at Ser 262/356.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Female; Ionophores; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Prosencephalon; Rats; Rats, Wistar; Serine; tau Proteins; Threonine; Time Factors; Up-Regulation | 2001 |
Calcium-induced alterations in the functioning of protein serine/threonine and tyrosine kinases in Streptomyces fradiae cells.
Topics: Calcium; Cell Division; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Ions; Phosphorylation; Protein Denaturation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; Streptomyces; Threonine; Time Factors; Tyrosine | 2000 |
Functional analysis of activation and repression domains of the rainbow trout aryl hydrocarbon receptor nuclear translocator (rtARNT) protein isoforms.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; DNA-Binding Proteins; Gene Deletion; Oncorhynchus mykiss; Proline; Protein Isoforms; Protein Structure, Tertiary; Receptors, Aryl Hydrocarbon; Serine; Signal Transduction; Threonine; Transcription Factors; Transcriptional Activation; Xenobiotics | 1999 |
Kaposi's sarcoma-associated herpesvirus K-bZIP protein is phosphorylated by cyclin-dependent kinases.
Topics: Amino Acid Sequence; Animals; Basic-Leucine Zipper Transcription Factors; COS Cells; Cyclin-Dependent Kinases; DNA-Binding Proteins; G-Box Binding Factors; Herpesvirus 8, Human; Molecular Sequence Data; Phosphorylation; Protein Isoforms; Rabbits; Serine; Threonine; Transcription Factors; Viral Proteins; Virus Activation; Virus Latency | 2001 |
Increased p53 phosphorylation after microtubule disruption is mediated in a microtubule inhibitor- and cell-specific manner.
Topics: Antineoplastic Agents; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Humans; Microtubules; Mutagenesis, Site-Directed; Paclitaxel; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Vincristine | 2001 |
Direct and differential interaction of beta-arrestins with the intracellular domains of different opioid receptors.
Topics: Amino Acid Sequence; Animals; Arrestins; beta-Arrestins; Binding Sites; Cell Line; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Serine; Structure-Activity Relationship; Threonine | 2001 |
Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins.
Topics: Adenoviridae; Androstadienes; Animals; Carcinoma, Hepatocellular; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; Insulin; Insulin Receptor Substrate Proteins; Liver Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Kinase C; Rats; Receptor, Insulin; Recombinant Proteins; Serine; Threonine; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Wortmannin | 2001 |
The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Catalysis; cdc42 GTP-Binding Protein; Conserved Sequence; HeLa Cells; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; p21-Activated Kinases; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 2001 |
Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Diprenorphine; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 2001 |
Involvement of pRB-related p107 protein in the inhibition of S phase progression in response to genotoxic stress.
Topics: Amino Acid Substitution; Animals; Cell Cycle; Cell Line; Chlorocebus aethiops; COS Cells; Culture Media, Conditioned; Humans; Hydroxyurea; Interleukin-3; Lymphocytes; Mice; Mutagenesis, Site-Directed; Nocodazole; Nuclear Proteins; Phosphorylation; Recombinant Proteins; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; S Phase; Sequence Deletion; Serine; Threonine; Transfection; Tumor Cells, Cultured | 2001 |
Investigation of invariant serine/threonine residues in mevalonate kinase. Tests of the functional significance of a proposed substrate binding motif and a site implicated in human inherited disease.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Arabidopsis; Bacteria; Binding Sites; Fluorescent Dyes; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine | 2001 |
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
Topics: Algorithms; Amino Acid Motifs; Amino Acid Sequence; Animals; Cattle; Databases, Factual; Genome; Humans; Internet; Mice; Molecular Sequence Data; Rats; Serine; Signal Transduction; Software; Threonine; Tyrosine | 2001 |
A systematic approach to the analysis of protein phosphorylation.
Topics: Amino Acid Sequence; Biochemistry; Caseins; Databases, Factual; Fungal Proteins; Gas Chromatography-Mass Spectrometry; Glucose; Glutathione Transferase; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Peptides; Phosphorylation; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Serine; Threonine; Time Factors; Tyrosine | 2001 |
Dual Ser and Thr phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by MYPT-associated kinase.
Topics: Animals; Apoptosis Regulatory Proteins; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Death-Associated Protein Kinases; In Vitro Techniques; Muscle Proteins; Myosin-Light-Chain Phosphatase; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Point Mutation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Threonine | 2001 |
Syntheses of alpha-dystroglycan derived glycosyl amino acids carrying a novel mannosyl serine/threonine linkage.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Cattle; Cytoskeletal Proteins; Dystroglycans; Glycosylation; Magnetic Resonance Spectroscopy; Mannose; Membrane Glycoproteins; Molecular Sequence Data; Oligosaccharides; Peripheral Nerves; Serine; Spectrometry, Mass, Fast Atom Bombardment; Threonine | 2000 |
Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Communication; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Female; Hepatocyte Growth Factor; Humans; Isoenzymes; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Proto-Oncogene Proteins c-met; Serine; Signal Transduction; src Homology Domains; Staurosporine; Threonine | 2001 |
Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9.
Topics: Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Asparagine; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Histidine; Humans; Hydroxylation; Isoleucine; Kinetics; Mephenytoin; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Peptide Fragments; Proline; Recombinant Fusion Proteins; Serine; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Threonine | 2001 |
Peptide bond formation mediated by 4,5-dimethoxy-2-mercaptobenzylamine after periodate oxidation of the N-terminal serine residue.
Topics: Amino Acid Sequence; Benzylamines; Chromatography, High Pressure Liquid; Glycine; Molecular Structure; Oxidation-Reduction; Peptides; Sequence Analysis, Protein; Serine; Structure-Activity Relationship; Sulfhydryl Compounds; Threonine | 2001 |
Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases.
Topics: Animals; Calcium; Carbachol; Carcinogens; Cholinergic Agents; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Estrenes; Isoenzymes; Male; Neurons; Parotid Gland; PC12 Cells; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; src-Family Kinases; Substance P; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates | 2001 |
Buried polar residues in coiled-coil interfaces.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Circular Dichroism; Crystallization; Crystallography, X-Ray; DNA-Binding Proteins; Fungal Proteins; Hot Temperature; Models, Molecular; Molecular Sequence Data; Peptides; Protein Kinases; Protein Structure, Secondary; Saccharomyces cerevisiae Proteins; Serine; Solutions; Threonine; Ultracentrifugation | 2001 |
Ray38p, a homolog of a purine motif triple-helical DNA-binding protein, Stm1p, is a ribosome-associated protein and dissociated from ribosomes prior to the induction of cycloheximide resistance in Candida maltosa.
Topics: Amino Acid Motifs; Amino Acid Substitution; Base Sequence; Candida; Cell Division; Cycloheximide; Eukaryotic Initiation Factors; Fungal Proteins; Molecular Sequence Data; Molecular Weight; Mutation; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Protein Binding; Protein Synthesis Inhibitors; Ribosomal Proteins; Ribosomes; RNA Nucleotidyltransferases; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Serine; Subcellular Fractions; Temperature; Threonine | 2001 |
Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants.
Topics: Actins; Binding Sites; Blood Platelets; Blotting, Western; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Mitogen-Activated Protein Kinases; Molecular Chaperones; Mutagenesis, Site-Directed; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Aggregation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Thionucleotides; Threonine; Time Factors | 2001 |
Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine.
Topics: Acetylglucosamine; Animals; Antibodies, Monoclonal; Antibody Specificity; Cell Extracts; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Immunoblotting; Immunoglobulin M; Jurkat Cells; Mice; Mice, Inbred BALB C; Precipitin Tests; Serine; Threonine | 2001 |
Identification of essential residues for catalysis of rat intestinal phospholipase B/lipase.
Topics: Amino Acids; Animals; Aspartic Acid; Catalytic Domain; COS Cells; Enzyme Activation; Glycine; Guinea Pigs; Histidine; Intestines; Lysophospholipase; Mutagenesis, Site-Directed; Rabbits; Rats; Repetitive Sequences, Amino Acid; Serine; Threonine | 2001 |
Carbon monoxide adducts of KatG and KatG(S315T) as probes of the heme site and isoniazid binding.
Topics: Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; Binding Sites; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Ferric Compounds; Heme; Isoniazid; Mycobacterium tuberculosis; Peroxidases; Serine; Spectrum Analysis, Raman; Threonine | 2001 |
Engineering a functional blue-wavelength-shifted rhodopsin mutant.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; COS Cells; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Photochemistry; Retinaldehyde; Rhodopsin; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Threonine; Transducin | 2001 |
Role of phylogenetically conserved amino acids in folding of Na,K-ATPase.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Cell Membrane; Conserved Sequence; Endoplasmic Reticulum; Enzyme Activation; Gene Expression Regulation, Fungal; Lysine; Mutagenesis, Site-Directed; Peptide Fragments; Phylogeny; Protein Folding; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Temperature; Threonine | 2001 |
Sodium ion-driven serine/threonine transport in Porphyromonas gingivalis.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Amino Acids; Bacterial Proteins; Biological Transport; Carrier Proteins; Cations, Monovalent; Culture Media; Genes, Bacterial; Molecular Sequence Data; Mutagenesis, Insertional; Porphyromonas gingivalis; Sequence Homology, Amino Acid; Serine; Sodium; Threonine | 2001 |
Reciprocity between O-GlcNAc and O-phosphate on the carboxyl terminal domain of RNA polymerase II.
Topics: Acetylglucosamine; Acetylglucosaminidase; beta-N-Acetylhexosaminidases; Carbohydrate Conformation; Circular Dichroism; Enzyme Activation; Glycosylation; Histone Acetyltransferases; Kinetics; Multienzyme Complexes; Peptide Fragments; Phosphates; Phosphorylation; Protein Conformation; Protein Kinase Inhibitors; Protein Kinases; Protein Structure, Tertiary; RNA Polymerase II; Serine; Substrate Specificity; Threonine | 2001 |
Solid-phase synthesis of beta-lactams via the Miller hydroxamate approach.
Topics: Anti-Bacterial Agents; beta-Lactams; Hydroxamic Acids; Hydroxylamines; Polystyrenes; Serine; Threonine | 2001 |
Mutation of residues 423 (Met/Ile), 444 (Thr/Met), and 506 (Asn/Ser) confer cholesteryl esterase activity on rat lung carboxylesterase. Ser-506 is required for activation by cAMP-dependent protein kinase.
Topics: Acetylcholinesterase; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Carboxylesterase; Carboxylic Ester Hydrolases; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Cytosol; DNA, Complementary; Enzyme Activation; Humans; Isoleucine; Liver; Lung; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Structure, Secondary; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Sterol Esterase; Threonine | 2001 |
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenoviridae; Amino Acids; Animals; Biological Transport; Carrier Proteins; Cell Cycle Proteins; Cell Line; Cysteine Endopeptidases; Cytosol; Deoxyglucose; Down-Regulation; Enzyme Inhibitors; Eukaryotic Initiation Factors; Glucose; Humans; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Mice; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Sirolimus; Subcellular Fractions; Threonine; Time Factors; TOR Serine-Threonine Kinases; Tyrosine | 2001 |
A phosphorylation-regulated brake mechanism controls the initial endocytosis of opioid receptors but is not required for post-endocytic sorting to lysosomes.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Arrestins; beta-Arrestins; Biotin; Cell Line; Cell Membrane; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Endocytosis; Etorphine; Green Fluorescent Proteins; Humans; Immunoblotting; Kinetics; Luminescent Proteins; Lysosomes; Mutation; Phosphorylation; Point Mutation; Protein Binding; Protein Structure, Tertiary; Receptors, Opioid; Recombinant Fusion Proteins; Serine; Threonine; Time Factors; Transfection | 2001 |
A PDZ domain protein interacts with the C-terminal tail of the insulin-like growth factor-1 receptor but not with the insulin receptor.
Topics: 3T3 Cells; Alternative Splicing; Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cell Division; Cell Movement; Cloning, Molecular; Cysteine; DNA, Complementary; Gene Deletion; Gene Library; Glutathione Transferase; Humans; Immunoblotting; Jurkat Cells; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Receptor, IGF Type 1; Receptor, Insulin; Serine; Signal Transduction; Threonine; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques | 2001 |
Effects of amino acid and trace element supplementation on pneumocandin production by Glarea lozoyensis: impact on titer, analogue levels, and the identification of new analogues of pneumocandin B(0).
Topics: Amino Acids; Anti-Bacterial Agents; Arginine; Ascomycota; Cations, Divalent; Chromatography, High Pressure Liquid; Echinocandins; Fermentation; Hydroxyproline; Peptides; Peptides, Cyclic; Proline; Serine; Threonine; Trace Elements | 2001 |
Evidence for isoniazid-dependent free radical generation catalyzed by Mycobacterium tuberculosis KatG and the isoniazid-resistant mutant KatG(S315T).
Topics: Aerobiosis; Amino Acid Substitution; Anaerobiosis; Antitubercular Agents; Bacterial Proteins; Catalysis; Cyclic N-Oxides; Drug Resistance, Microbial; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Horseradish Peroxidase; Hydrazines; Isoniazid; Kinetics; Mycobacterium tuberculosis; Nicotinic Acids; Nitrogen Oxides; Peroxidases; Serine; Spin Labels; Spin Trapping; Threonine | 2001 |
The role of amino acids in the regulation of hydrogen sulfide production during ultradian respiratory oscillation of Saccharomyces cerevisiae.
Topics: Aerobiosis; Amino Acids; Biological Clocks; Cell Respiration; Culture Media; Cysteine; Homoserine; Hydrogen Sulfide; Methionine; Oscillometry; Periodicity; Saccharomyces cerevisiae; Serine; Sulfur Compounds; Threonine | 2001 |
The Calpha ---H...O hydrogen bond: a determinant of stability and specificity in transmembrane helix interactions.
Topics: Amino Acid Sequence; Glycine; Hydrogen Bonding; Membrane Proteins; Protein Conformation; Serine; Threonine | 2001 |
Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.
Topics: Animals; Apoptosis; B-Lymphocytes; Cell Nucleus; Cells, Cultured; Cytochrome c Group; Cytosol; DNA Fragmentation; Enzyme Inhibitors; Humans; Imidazoles; Immunologic Memory; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Microscopy, Fluorescence; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Growth Factor; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Recombinant Proteins; Serine; Threonine; Time Factors | 2001 |
The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells.
Topics: Animals; Blotting, Western; Catalysis; Cell Line; DNA Mutational Analysis; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Genes, Reporter; Hedgehog Proteins; Insect Proteins; Membrane Proteins; Mutation; Phosphorylation; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Receptors, Cell Surface; Serine; Signal Transduction; Threonine; Transcription Factors; Transcription, Genetic; Transfection | 2001 |
FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1.
Topics: Blotting, Western; Carboxylic Acids; Cell Line; Ceramides; Diacylglycerol Kinase; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Fumonisins; Humans; Jurkat Cells; Palmitic Acid; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; Sarcoplasmic Reticulum; Serine; Sphingolipids; Threonine; Time Factors | 2001 |
UV Induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal Cl 41 cells through hydrogen peroxide.
Topics: Animals; Epidermal Cells; Epidermis; Flavonoids; Free Radical Scavengers; Hydrogen Peroxide; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Serine; Threonine; Ultraviolet Rays | 2001 |
Access of a membrane protein to secretory granules is facilitated by phosphorylation.
Topics: Casein Kinase II; Dichlororibofuranosylbenzimidazole; Endocytosis; Endosomes; Membrane Proteins; Mixed Function Oxygenases; Models, Biological; Multienzyme Complexes; Mutation; Peptide Fragments; Phosphorylation; Protein Serine-Threonine Kinases; Protein Sorting Signals; Protein Transport; Recombinant Proteins; Secretory Vesicles; Serine; Threonine; trans-Golgi Network | 2001 |
Benzamide bioisosteres incorporating dihydroheteroazole substructures: EPC synthesis and SAR leading to a selective dopamine D4 receptor partial agonist (FAUC 179).
Topics: Animals; Biochemistry; Cattle; CHO Cells; Clozapine; Cricetinae; Cysteine; Dopamine Antagonists; Drug Design; Humans; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Molecular Structure; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D4; Serine; Spiperone; Stereoisomerism; Structure-Activity Relationship; Threonine | 2001 |
STRICA, a novel Drosophila melanogaster caspase with an unusual serine/threonine-rich prodomain, interacts with DIAP1 and DIAP2.
Topics: Amino Acid Sequence; Animals; Apoptosis; Caspases; Cell Line; Cloning, Molecular; Dimerization; Drosophila melanogaster; Drosophila Proteins; Inhibitor of Apoptosis Proteins; Insect Proteins; Molecular Sequence Data; Phylogeny; Protein Structure, Tertiary; RNA, Messenger; Serine; Threonine; Transfection; Two-Hybrid System Techniques | 2001 |
Site-dependent effect of O-glycosylation on the conformation and biological activity of calcitonin.
Topics: Acetylgalactosamine; Amino Acid Sequence; Animals; Biological Assay; Calcitonin; Eels; Glycosylation; Hypocalcemia; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; Receptors, Calcitonin; Serine; Structure-Activity Relationship; Threonine | 2001 |
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
Topics: Cell Cycle; Cell Cycle Proteins; DNA; DNA Damage; HeLa Cells; Humans; Phosphorylation; Serine; Threonine | 2001 |
IgE receptor type I-dependent regulation of a Rab3D-associated kinase: a possible link in the calcium-dependent assembly of SNARE complexes.
Topics: Animals; Calcium; Carrier Proteins; Cell Line; COS Cells; Down-Regulation; Gene Deletion; Immunoblotting; Mast Cells; Membrane Proteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Qa-SNARE Proteins; Qb-SNARE Proteins; Qc-SNARE Proteins; rab GTP-Binding Proteins; rab3 GTP-Binding Proteins; Receptors, IgE; Recombinant Proteins; Serine; SNARE Proteins; Threonine; Transfection; Vesicular Transport Proteins | 2001 |
Solid-phase glycosylation of peptide templates and on-bead MAS-NMR analysis: perspectives for glycopeptide libraries.
Topics: Amino Acid Sequence; Carbohydrate Conformation; Glycopeptides; Glycosylation; Indicators and Reagents; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Conformation; Serine; Threonine; Tyrosine | 2001 |
Tumour necrosis factor-alpha activation of protein kinase B in WEHI-164 cells is accompanied by increased phosphorylation of Ser473, but not Thr308.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Antineoplastic Agents; Cell Line; Cell Membrane; Cell Survival; Enzyme Activation; Enzyme Inhibitors; GTPase-Activating Proteins; Humans; Insulin-Like Growth Factor I; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Serine; Signal Transduction; Threonine; Transfection; Tumor Necrosis Factor-alpha | 2001 |
IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells.
Topics: Animals; Binding, Competitive; Cell Line; Cell Nucleus; Cloning, Molecular; Cytoplasm; Dimerization; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glutamic Acid; HeLa Cells; Humans; I-kappa B Proteins; Kinetics; Mice; Microscopy, Fluorescence; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Localization Signals; Plasmids; Proline; Protein Binding; Serine; Signal Transduction; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2001 |
Electrochemical evaluation of the interfacial capacitance upon phosphorylation of amino acid analogue molecular films.
Topics: Amino Acids; Electrochemistry; Phosphorylation; Serine; Spectrophotometry, Infrared; Threonine; Tyrosine | 2001 |
Phosphorylation of Ser2078 modulates the Notch2 function in 32D cell differentiation.
Topics: Amino Acid Sequence; Amino Acids; Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Cytokines; Gene Deletion; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Immunoblotting; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Phosphorylation; Plasmids; Protein Structure, Tertiary; Rats; Receptor, Notch2; Receptors, Cell Surface; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Time Factors; Transcriptional Activation | 2001 |
Inhibition of integrin-linked kinase/protein kinase B/Akt signaling: mechanism for ganglioside-induced apoptosis.
Topics: Apoptosis; Binding Sites; Caspase 9; Caspases; Cell Cycle; Cell Line; Cell Movement; Cell Survival; Culture Media, Serum-Free; Cyclin D; Cyclin E; Cyclins; Cytochrome c Group; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Precursors; Fibronectins; G1 Phase; Gangliosides; Humans; Immunoblotting; Keratinocytes; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Time Factors | 2001 |
The osteopontin-CD44 survival signal involves activation of the phosphatidylinositol 3-kinase/Akt signaling pathway.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Survival; DNA Primers; Enzyme Activation; Hyaluronan Receptors; Interleukin-3; Mice; Molecular Sequence Data; Osteopontin; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sequence Homology, Amino Acid; Serine; Sialoglycoproteins; Signal Transduction; Threonine | 2001 |
The capsid protein of a plant single-stranded RNA virus is modified by O-linked N-acetylglucosamine.
Topics: Acetylglucosamine; Amino Acid Sequence; Capsid; Capsid Proteins; Galactose; Molecular Sequence Data; Phosphorylation; Serine; Threonine | 2002 |
Xenopus phospho-CDK7/cyclin H expressed in baculoviral-infected insect cells.
Topics: Animals; Baculoviridae; CDC2-CDC28 Kinases; Cell Line; Cloning, Molecular; Cyclin A; Cyclin H; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Cyclins; Macromolecular Substances; Mass Spectrometry; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Spodoptera; Threonine; Xenopus laevis; Xenopus Proteins | 2001 |
Decreased expression of phospholamban is not associated with lower beta-adrenergic activation in rat atria.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atrial Function; Calcium; Calcium-Binding Proteins; Female; Heart Atria; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phosphorylation; Propranolol; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Serine; Threonine; Tissue Extracts; Ventricular Function | 2001 |
Hierarchical phosphorylation of the translation inhibitor 4E-BP1.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Cell Line; DNA Mutational Analysis; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Isoelectric Focusing; Mass Spectrometry; Molecular Sequence Data; Mutation; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Ribosomes; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Sirolimus; Spectrometry, Fluorescence; Threonine; Transfection | 2001 |
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein.
Topics: Amino Acid Sequence; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Binding Sites; Bucladesine; Cantharidin; Carbohydrate Metabolism; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucose; Helix-Loop-Helix Motifs; Isoquinolines; Leucine Zippers; Male; Mice; Molecular Sequence Data; Mutagenesis; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; Response Elements; Serine; Subcellular Fractions; Sulfonamides; Threonine; Transcription Factors; Transcription, Genetic | 2001 |
PKC-gamma phosphorylation of connexin 46 in the lens cortex.
Topics: Animals; Blotting, Western; Connexins; Enzyme Inhibitors; Isoenzymes; Lens Cortex, Crystalline; Microscopy, Confocal; Peptides; Phosphorylation; Protein Kinase C; Rats; Serine; Threonine | 2001 |
Nuclear localization of the plant protein Ser/Thr phosphatase PP7.
Topics: Abscisic Acid; Active Transport, Cell Nucleus; Amino Acid Sequence; Arabidopsis Proteins; Catalytic Domain; Cell Nucleus; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Green Fluorescent Proteins; Luminescent Proteins; Microscopy, Confocal; Molecular Sequence Data; Phosphoprotein Phosphatases; Plants, Genetically Modified; Plasmids; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Threonine; Time Factors | 2001 |
The activated glucocorticoid receptor modulates presumptive autoregulation of ribosomal protein S6 protein kinase, p70 S6K.
Topics: Animals; Blotting, Western; Cell Line; CHO Cells; COS Cells; Cricetinae; Dexamethasone; DNA; DNA Mutational Analysis; DNA, Complementary; Epitopes; Glucocorticoids; Humans; Mifepristone; Models, Biological; Phosphorylation; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Rats; Receptors, Glucocorticoid; Ribosomal Protein S6 Kinases; RNA, Messenger; Serine; Threonine; Time Factors | 2002 |
Precursor structure of cephalosporin acylase. Insights into autoproteolytic activation in a new N-terminal hydrolase family.
Topics: Binding Sites; Dimerization; Glycine; Models, Molecular; Multigene Family; Penicillin Amidase; Protein Binding; Protein Precursors; Protein Structure, Tertiary; Pseudomonas; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Threonine | 2002 |
Regulation of the accumulation and function of p53 by phosphorylation of two residues within the domain that binds to Mdm2.
Topics: Base Sequence; Binding Sites; Blotting, Northern; Blotting, Western; DNA Damage; DNA Primers; Doxorubicin; Humans; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Serine; Threonine; Transcriptional Activation; Tumor Suppressor Protein p53 | 2002 |
Gbeta residues that do not interact with Galpha underlie agonist-independent activity of K+ channels.
Topics: Amino Acid Sequence; Amino Acids; Animals; DNA, Complementary; Electrophysiology; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutathione Transferase; GTP-Binding Protein beta Subunits; Heterotrimeric GTP-Binding Proteins; Immunoblotting; Insecta; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Oocytes; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Time Factors; Xenopus laevis | 2002 |
Importance of the conserved nucleotides around the tRNA-like structure of Escherichia coli transfer-messenger RNA for protein tagging.
Topics: Acylation; Alanine; Arginine; Bacterial Proteins; Base Sequence; Binding Sites; Blotting, Northern; Conserved Sequence; Escherichia coli; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Open Reading Frames; Peptide Elongation Factor Tu; Ribosomal Proteins; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine | 2001 |
Tight-junction protein zonula occludens 2 is a target of phosphorylation by protein kinase C.
Topics: Animals; Calcium; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dogs; Glutathione Transferase; Isoenzymes; Membrane Proteins; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Serine; Threonine; Tight Junctions; Zonula Occludens-2 Protein | 2001 |
The linkage between beta1 integrin and the actin cytoskeleton is differentially regulated by tyrosine and serine/threonine phosphorylation of beta1 integrin in normal and cancerous human breast cells.
Topics: Actin Cytoskeleton; Actinin; Actins; Amino Acid Sequence; Breast; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Epithelial Cells; Female; Humans; Integrin beta1; Molecular Sequence Data; Phosphorylation; Precipitin Tests; Serine; Threonine; Tumor Cells, Cultured; Tyrosine | 2001 |
Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function.
Topics: Cell Cycle; DNA; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Microscopy, Fluorescence; Mitosis; Mutation; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Phosphoserine; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Time Factors | 2002 |
Functional evaluation of serine/threonine residues in the P-Loop of Rhodobacter sphaeroides phosphoribulokinase.
Topics: Adenosine Triphosphate; Binding Sites; Electron Spin Resonance Spectroscopy; Ligands; Models, Molecular; Mutagenesis, Site-Directed; NAD; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphotransferases (Alcohol Group Acceptor); Rhodobacter sphaeroides; Serine; Threonine | 2001 |
Phosphorylation regulates the nucleocytoplasmic distribution of kinase suppressor of Ras.
Topics: Active Transport, Cell Nucleus; Binding Sites; Biological Transport; Blotting, Western; Cell Line; Cell Nucleus; Cytoplasm; Fatty Acids, Unsaturated; Fibroblasts; Green Fluorescent Proteins; Humans; Luminescent Proteins; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Kinases; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Time Factors | 2002 |
Cobalamin deficiency results in severe metabolic disorder of serine and threonine in rats.
Topics: Animals; Diet; L-Serine Dehydratase; Liver; Male; Methylmalonic Acid; Rats; Rats, Wistar; Serine; Threonine; Vitamin B 12 | 2001 |
Phosphorylation of the protein kinase C-theta activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-kappaB induction.
Topics: Amino Acid Motifs; Amino Acid Sequence; Catalysis; Enzyme Activation; Humans; Isoenzymes; Jurkat Cells; Models, Molecular; Molecular Sequence Data; Mutation; NF-kappa B; Phosphorylation; Protein Conformation; Protein Kinase C; Protein Kinase C-theta; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2002 |
The late-domain-containing protein p6 is the predominant phosphoprotein of human immunodeficiency virus type 1 particles.
Topics: Cell Line; Cyclin-Dependent Kinases; Endopeptidases; Enzyme Inhibitors; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Genistein; HIV-1; Humans; Kinetin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Purines; Serine; Threonine; Tyrosine; Virion | 2002 |
Determination of the site-specific oligosaccharide distribution of the O-glycans attached to the porcine submaxillary mucin tandem repeat. Further evidence for the modulation of O-glycans side chain structures by peptide sequence.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carbohydrate Sequence; Fucosyltransferases; Galactoside 2-alpha-L-fucosyltransferase; Glycosylation; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Mucins; Oligosaccharides; Peptides; Polysaccharides; Protein Binding; Protein Structure, Tertiary; Serine; Swine; Threonine; Trisaccharides | 2002 |
Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation.
Topics: Adjuvants, Immunologic; Androstadienes; Animals; Blotting, Western; Bromodeoxyuridine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Chromones; COS Cells; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Immunoblotting; Lithium Chloride; Morpholines; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Time Factors; Transfection; Umbilical Veins; Wortmannin | 2002 |
Transactivation of ErbB2 and ErbB3 by tumor necrosis factor-alpha and anisomycin leads to impaired insulin signaling through serine/threonine phosphorylation of IRS proteins.
Topics: Anisomycin; Cycloheximide; Genes, erbB; Genes, erbB-2; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Neuregulin-1; Phosphatidylinositol 3-Kinases; Phosphoproteins; Serine; Threonine; Transcriptional Activation; Tumor Necrosis Factor-alpha; Tyrosine | 2002 |
Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association.
Topics: Animals; Butadienes; Cell Adhesion; Cell Line; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epithelial Cells; Escherichia coli; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glutathione Transferase; Hepatocyte Growth Factor; Kidney Tubules; MAP Kinase Signaling System; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Nitriles; Paxillin; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Serine; Threonine; Time Factors; Tyrosine | 2002 |
Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinases.
Topics: Agammaglobulinaemia Tyrosine Kinase; Blood Platelets; Blotting, Western; Calcium; Crotalid Venoms; Cytosol; Glutathione Transferase; Humans; Isoenzymes; Models, Biological; Myelin Basic Protein; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-theta; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Recombinant Fusion Proteins; Serine; Serotonin; Signal Transduction; Threonine; Time Factors; Tyrosine | 2002 |
Phosphorylation-dependent functional coupling of hSlo calcium-dependent potassium channel and its hbeta 4 subunit.
Topics: Animals; Binding Sites; Blotting, Western; Cell Line; CHO Cells; Cricetinae; Electrophysiology; Enzyme Inhibitors; Humans; Kinetics; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Mutation; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Potassium Channels; Potassium Channels, Calcium-Activated; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Serine; Threonine; Time Factors | 2002 |
Characterization of a major sporozoite surface glycoprotein of Cryptosporidum parvum.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens, Protozoan; Base Sequence; Biotinylation; Blotting, Western; Consensus Sequence; Cryptosporidium parvum; Glycosylation; Membrane Glycoproteins; Microscopy, Fluorescence; Molecular Sequence Data; Protozoan Proteins; Recombinant Proteins; Sequence Analysis, Protein; Serine; Spores; Threonine | 2000 |
Efficient semisynthesis of a tetraphosphorylated analogue of the Type I TGFbeta receptor.
Topics: Activin Receptors, Type I; Amino Acid Motifs; Electrophoresis, Polyacrylamide Gel; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Resins, Synthetic; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2002 |
Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1.
Topics: Alanine; Alleles; Asparagine; Binding Sites; Calcium; Calcium Channels; Codon; Codon, Nonsense; Cysteine; Fungal Proteins; Hydroxylamine; Immunoblotting; Membrane Glycoproteins; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Time Factors; Tryptophan; Two-Hybrid System Techniques | 2002 |
The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression.
Topics: Animals; Ankyrins; Apoptosis; Cell Division; Cell Line; Cell Nucleus; COS Cells; Cytosol; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Dominant; Humans; Hyaluronoglucosaminidase; Hypoxia; I-kappa B Proteins; Liver; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Spleen; Staurosporine; Threonine; Time Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays | 2002 |
The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites.
Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Cell Cycle Proteins; Cell Line; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Serine; Tetradecanoylphorbol Acetate; Threonine | 2002 |
MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.
Topics: Amino Acid Motifs; Binding Sites; Dimerization; Genetic Diseases, X-Linked; Humans; Ligases; Microtubule Proteins; Microtubule-Associated Proteins; Microtubules; Nuclear Proteins; Phosphoprotein Phosphatases; Phosphorylation; Protein Binding; Protein Subunits; Regulatory Sequences, Nucleic Acid; Sequence Deletion; Serine; Signal Transduction; Sirolimus; Smith-Lemli-Opitz Syndrome; Threonine; Transcription Factors; Two-Hybrid System Techniques; Ubiquitin-Protein Ligases | 2002 |
Hydration effects of heparin on antithrombin probed by osmotic stress.
Topics: Alanine; Antithrombins; Asparagine; Binding Sites; Heparin; Isoleucine; Kinetics; Leucine; Models, Molecular; Osmotic Pressure; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Threonine; Time Factors; Tryptophan; Valine; Water; X-Rays | 2002 |
Contraction regulation of Akt in rat skeletal muscle.
Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Insulin; Morpholines; Muscle Contraction; Muscle, Skeletal; Phosphorylation; Protein Binding; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine; Wortmannin | 2002 |
Time course and mechanisms of phosphorylation of phospholamban residues in ischemia-reperfused rat hearts. Dissociation of phospholamban phosphorylation pathways.
Topics: Animals; Blotting, Western; Calcium; Calcium-Binding Proteins; Catecholamines; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Heart; Ischemia; Male; Myocardium; Phosphorylation; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Reperfusion Injury; Sarcoplasmic Reticulum; Serine; Sodium-Calcium Exchanger; Thiourea; Threonine; Time Factors | 2002 |
Mechanisms of regulation of phospholipase D1 and D2 by the heterotrimeric G proteins G13 and Gq.
Topics: Animals; Brain; Clostridium botulinum; COS Cells; Cysteine; DNA-Binding Proteins; Enzyme Activation; Genes, Dominant; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Mutation; Palmitic Acid; Phorbol Esters; Phospholipase D; Phosphorylation; Plasmids; Protein Binding; Protein Kinase C; Protein Processing, Post-Translational; Rats; rhoA GTP-Binding Protein; Serine; Threonine; Transfection | 2002 |
Yeast cystathionine beta-synthase reacts with L-allothreonine, a non-natural substrate, and L-homocysteine to form a new amino acid, 3-methyl-L-cystathionine.
Topics: Circular Dichroism; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Kinetics; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Saccharomyces cerevisiae; Serine; Spectrophotometry; Substrate Specificity; Threonine | 2002 |
Altered regulation of SHP-2 and PTP 1B tyrosine phosphatases in cystic kidneys from bcl-2 -/- mice.
Topics: Animals; Cell Differentiation; Cytoskeletal Proteins; Epithelial Cells; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Enzymologic; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Kidney Diseases, Cystic; Leukemia, B-Cell; Lymphoma, B-Cell; Male; Mice; Mice, Mutant Strains; Paxillin; Phosphoproteins; Phosphorylation; Pregnancy; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-2; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Threonine | 2002 |
Wnt signaling controls the phosphorylation status of beta-catenin.
Topics: Animals; Antibodies, Monoclonal; Base Sequence; beta Catenin; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Mice; Molecular Sequence Data; Phosphorylation; Point Mutation; Pregnancy; Proto-Oncogene Proteins; Serine; Signal Transduction; Structure-Activity Relationship; Threonine; Trans-Activators; Transfection; Wnt Proteins; Zebrafish Proteins | 2002 |
Definitive expression of c-mos in late meiotic prophase leads to phosphorylation of a 34 kda protein in cultured rat spermatocytes.
Topics: Animals; Blotting, Western; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isoelectric Focusing; Male; MAP Kinase Signaling System; Meiosis; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-mos; Rats; Serine; Signal Transduction; Spermatocytes; Threonine; Time Factors | 2002 |
Identification of syntaxin-1A sites of phosphorylation by casein kinase I and casein kinase II.
Topics: Amino Acid Sequence; Animals; Antigens, Surface; Casein Kinase II; Casein Kinases; Cyclic AMP-Dependent Protein Kinases; Molecular Sequence Data; Nerve Tissue Proteins; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; Serine; Syntaxin 1; Threonine | 2002 |
A 45-kDa protein kinase related to mitogen-activated protein kinase is activated in tobacco cells treated with a phorbol ester.
Topics: Cells, Cultured; Cycloheximide; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Weight; Nicotiana; Phosphorylation; Plant Proteins; Serine; Stress, Mechanical; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2002 |
Motifs of serine and threonine can drive association of transmembrane helices.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; Computational Biology; Databases, Protein; Escherichia coli; Halorhodopsins; Humans; Hydrogen Bonding; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Library; Protein Binding; Protein Structure, Secondary; Serine; Thermodynamics; Threonine | 2002 |
RhoA and Rho kinase-dependent phosphorylation of moesin at Thr-558 in hippocampal neuronal cells by glutamate.
Topics: Animals; Brain; cdc42 GTP-Binding Protein; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Electroshock; Glutamic Acid; Hippocampus; Immunoblotting; Intracellular Signaling Peptides and Proteins; Male; Microfilament Proteins; Neurons; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Recombinant Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Threonine; Time Factors; Transfection | 2002 |
Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors.
Topics: 3C Viral Proteases; Cyclization; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Escherichia coli; Fatty Acids, Unsaturated; Hepatovirus; Lactones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Orlistat; Serine; Stereoisomerism; Structure-Activity Relationship; Threonine; Viral Proteins | 2002 |
Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Binding Sites; Blotting, Western; Cell Line; CHO Cells; Cricetinae; DNA, Complementary; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Insulin; Mice; Mutagenesis, Site-Directed; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Threonine; Transfection | 2002 |
Mucin-like domain of enteropeptidase directs apical targeting in Madin-Darby canine kidney cells.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Animals; Cell Line; Centrifugation, Density Gradient; Dogs; Glycoside Hydrolases; Glycosylation; Green Fluorescent Proteins; Kidney; Luminescent Proteins; Membrane Microdomains; Molecular Sequence Data; Mucins; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Time Factors; Transfection | 2002 |
Application of serine- and threonine-derived cyclic sulfamidates for the preparation of S-linked glycosyl amino acids in solution- and solid-phase peptide synthesis.
Topics: Amino Acids; Glycopeptides; Glycosylation; Peptides; Serine; Solutions; Sulfonamides; Threonine | 2002 |
Phosphorylation at threonine-18 in addition to phosphorylation at serine-19 on myosin-II regulatory light chain is a mitosis-specific event.
Topics: Amino Acid Sequence; Antibody Specificity; Cell Cycle; Cell Division; Cytoskeleton; DNA; Fluorescent Antibody Technique; HeLa Cells; Humans; Mitosis; Myosin Light Chains; Myosin Type II; Phosphorylation; Serine; Threonine | 2002 |
Human Herpesvirus 6 immediate-early 1 protein is a sumoylated nuclear phosphoprotein colocalizing with promyelocytic leukemia protein-associated nuclear bodies.
Topics: Cell Nucleus; Cell-Free System; Cloning, Molecular; DNA, Complementary; Exons; Genetic Vectors; Glutathione Transferase; Herpesvirus 6, Human; Humans; Immediate-Early Proteins; Kinetics; Models, Genetic; Molecular Sequence Data; Neoplasm Proteins; Nuclear Proteins; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Promyelocytic Leukemia Protein; Protein Binding; Protein Biosynthesis; Protein Processing, Post-Translational; Recombinant Fusion Proteins; RNA; RNA, Messenger; Serine; Spectrometry, Fluorescence; Threonine; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site.
Topics: Androstadienes; Animals; Antibiotics, Antineoplastic; Binding Sites; Cell Line; Enzyme Inhibitors; Genes, Dominant; Glutathione Transferase; Humans; Immunoblotting; Insulin; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Ribosomal Protein S6 Kinases; Serine; Sirolimus; Threonine; Transfection; Wortmannin | 2002 |
Protein kinase C phosphorylation of purified Na,K-ATPase: C-terminal phosphorylation sites at the alpha- and gamma-subunits close to the inner face of the plasma membrane.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; Cytoplasm; Detergents; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Kidney; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Threonine; Trypsin | 2002 |
Engineering of multiple arginines into the Ser/Thr surface of Trichoderma reesei endo-1,4-beta-xylanase II increases the thermotolerance and shifts the pH optimum towards alkaline pH.
Topics: Arginine; Catalytic Domain; Endo-1,4-beta Xylanases; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Mutation; Protein Conformation; Protein Engineering; Serine; Temperature; Threonine; Trichoderma; Xylosidases | 2002 |
Epidermal growth factor stimulates serine/threonine phosphorylation of the focal adhesion protein paxillin in a MEK-dependent manner in normal rat kidney cells.
Topics: Actins; Animals; Cell Adhesion; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Enzyme Activation; Epidermal Growth Factor; Kidney; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Paxillin; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Reference Values; Serine; Threonine | 2002 |
Protein phosphatase 2A is involved in the regulation of protein kinase A signaling pathway during in vitro chondrogenesis.
Topics: Animals; Cartilage; Cell Differentiation; Cell Division; Cells, Cultured; Chick Embryo; Chondrocytes; Chondrogenesis; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoquinolines; Limb Buds; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Serine; Signal Transduction; Sulfonamides; Threonine; Time Factors | 2002 |
Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Armadillo Domain Proteins; Casein Kinases; Cell Line; Dishevelled Proteins; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Insect Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins; RNA, Antisense; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Trans-Activators; Transcription Factors; Wnt1 Protein | 2002 |
Biochemical characterization of the kinase domain of the rice disease resistance receptor-like kinase XA21.
Topics: Amino Acid Sequence; Base Sequence; DNA Primers; Kinetics; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Plant Proteins; Protein Serine-Threonine Kinases; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Threonine | 2002 |
Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes.
Topics: Animals; beta Catenin; Cell Nucleus; Cells, Cultured; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Hepatocyte Growth Factor; Hepatocytes; Male; Phosphorylation; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Rats; Rats, Inbred F344; Serine; Signal Transduction; Threonine; Trans-Activators; Wnt Proteins; Wnt1 Protein; Zebrafish Proteins | 2002 |
Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102.
Topics: Amino Acid Sequence; Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Anisotropy; Brain; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Frizzled Receptors; Genome, Human; Glutathione Transferase; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Isoenzymes; Kinetics; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Nerve Tissue Proteins; Neuropeptides; Nuclear Proteins; Peptides; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Tertiary; Proteins; Rats; Receptors, G-Protein-Coupled; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Transcription Factors | 2002 |
The initiation factor eIF4A is involved in the response to lithium stress in Saccharomyces cerevisiae.
Topics: Blotting, Western; Carrier Proteins; Enzyme Inhibitors; Escherichia coli; Eukaryotic Initiation Factor-4A; Fermentation; Galactose; Immunoblotting; Lithium; Lithium Chloride; Nuclear Receptor Coactivator 2; Peptide Initiation Factors; Phosphoglucomutase; Phosphoprotein Phosphatases; Polyribosomes; Protein Binding; Protein Phosphatase 2; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Time Factors; Transcription Factors | 2002 |
The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status.
Topics: Amino Acid Sequence; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA; Dopamine beta-Hydroxylase; Electrophoresis, Gel, Two-Dimensional; Genes, Reporter; Homeodomain Proteins; Humans; Models, Biological; Molecular Sequence Data; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Serine; Signal Transduction; Threonine; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine | 2002 |
PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway.
Topics: Blotting, Western; Cell Line; Enzyme Activation; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; p21-Activated Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Serine; Threonine | 2002 |
Description of a cellulose-binding domain and a linker sequence from Aspergillus fungi.
Topics: Amino Acid Sequence; Aspergillus; Cellulose; Cloning, Molecular; Crystallization; Escherichia coli; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Threonine | 2002 |
High prevalence of KatG Ser315Thr substitution among isoniazid-resistant Mycobacterium tuberculosis clinical isolates from northwestern Russia, 1996 to 2001.
Topics: Adolescent; Adult; Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Peroxidases; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Russia; Serine; Threonine; Tuberculosis, Pulmonary | 2002 |
Regulation of novel protein kinase C epsilon by phosphorylation.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; 3T3 Cells; Amino Acid Sequence; Animals; Enzyme Inhibitors; Humans; Isoenzymes; Mice; Molecular Sequence Data; Okadaic Acid; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Serine-Threonine Kinases; Sequence Alignment; Serine; Threonine | 2002 |
Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Blood Proteins; Casein Kinase II; Caspase 3; Caspases; Cell Death; Cell Survival; Cytochrome c Group; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Humans; Jurkat Cells; Phosphorylation; Poly(ADP-ribose) Polymerases; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Serine; Threonine; Time Factors; Triazoles; Tyrosine | 2002 |
O-phospho-L-tyrosine protects TP53 wild-type cells against ionizing radiation.
Topics: Blotting, Western; Cell Line, Transformed; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Complementary; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Mutation; Neoplasms; Phosphotyrosine; Radiation-Protective Agents; Serine; Threonine; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Inhibitory effects of a luteinizing hormone-releasing hormone agonist on basal and epidermal growth factor-induced cell proliferation and metastasis-associated properties in human epidermoid carcinoma A431 cells.
Topics: Antineoplastic Agents, Hormonal; Carcinoma, Squamous Cell; Caspases; Cell Division; DNA Fragmentation; Enzyme Activation; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Humans; Immunoblotting; Matrix Metalloproteinases; Neoplasm Invasiveness; Phosphorylation; Precipitin Tests; Protein Tyrosine Phosphatases; Serine; Threonine; Time Factors; Triptorelin Pamoate; Tumor Cells, Cultured | 2002 |
Phosphorylation and flexibility of cyclic-AMP-dependent protein kinase (PKA) using (31)P NMR spectroscopy.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphorus; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Serine; Threonine | 2002 |
A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain.
Topics: 3T3 Cells; Adipocytes; Amino Acid Motifs; Animals; Biochemistry; COS Cells; Cytosol; Humans; Immunoblotting; Insulin; Mass Spectrometry; Mice; Microsomes; Mutation; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; rab GTP-Binding Proteins; Serine; Threonine | 2002 |
DNA ligase III is degraded by calpain during cell death induced by DNA-damaging agents.
Topics: Amino Acid Motifs; Amino Acid Substitution; Apoptosis; Aspartic Acid; Calpain; DNA Damage; DNA Ligase ATP; DNA Ligases; Humans; Mutagenesis, Site-Directed; Poly-ADP-Ribose Binding Proteins; Proline; Recombinant Proteins; Serine; Threonine; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques; Xenopus Proteins | 2002 |
Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1.
Topics: Amino Acid Sequence; Animals; Cell Cycle; Cell Cycle Proteins; Evolution, Molecular; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spodoptera; Threonine; Xenopus; Xenopus Proteins | 2002 |
Amino acid- and lipid-induced insulin resistance in rat heart: molecular mechanisms.
Topics: Amino Acids; Animals; Biological Transport; Glucose; Glycogen Synthase Kinase 3; Heart; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Mitogen-Activated Protein Kinases; Myocardium; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Threonine; Tyrosine | 2002 |
Mechanism of N-terminal autoinhibition in the Arabidopsis Ca(2+)/H(+) antiporter CAX1.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antiporters; Arabidopsis; Calcium; Calcium-Binding Proteins; Cation Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine; Structure-Activity Relationship; Threonine | 2002 |
Identification of the catalytic residues of alpha-amino acid ester hydrolase from Acetobacter turbidans by labeling and site-directed mutagenesis.
Topics: Acetobacter; Amino Acid Sequence; Anti-Bacterial Agents; Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Circular Dichroism; Cloning, Molecular; Conserved Sequence; Electrophoresis, Polyacrylamide Gel; Kinetics; Lactams; Methionine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Plasmids; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Time Factors | 2002 |
Phospholipase D1 is threonine-phosphorylated in human-airway epithelial cells stimulated by sphingosine-1-phosphate by a mechanism involving Src tyrosine kinase and protein kinase Cdelta.
Topics: Acetophenones; Benzopyrans; Cell Line; Cell Membrane; Cytosol; Enzyme Inhibitors; Epithelial Cells; Genistein; Glycerophospholipids; Humans; Isoenzymes; Lysophospholipids; Nasal Cavity; Oligonucleotides, Antisense; Phosphatidic Acids; Phospholipase D; Phosphorylation; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Proto-Oncogene Proteins pp60(c-src); Respiratory Mucosa; Serine; Sphingosine; Subcellular Fractions; Threonine; Time Factors | 2002 |
Phosphorylation of the myosin phosphatase target subunit by integrin-linked kinase.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Catalytic Domain; Chickens; Chromatography, High Pressure Liquid; Cyclic AMP; Dose-Response Relationship, Drug; Molecular Sequence Data; Muscle, Smooth; Mutation; Myosin-Light-Chain Phosphatase; Phosphoprotein Phosphatases; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Serine; Threonine; Time Factors | 2002 |
The synergistic anion-binding sites of human transferrin: chemical and physiological effects of site-directed mutagenesis.
Topics: Alanine; Anions; Arginine; Binding Sites; Carbonic Acid; Drug Synergism; Electron Spin Resonance Spectroscopy; Humans; Iron; K562 Cells; Kinetics; Mutagenesis, Site-Directed; Nitrilotriacetic Acid; Peptide Fragments; Recombinant Proteins; Serine; Spectrophotometry; Threonine; Transferrin | 2002 |
The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3.
Topics: ADAM Proteins; ADAM17 Protein; Amino Acid Substitution; Catalytic Domain; Enzyme Inhibitors; Hydroxamic Acids; Kinetics; Leucine; Metalloendopeptidases; Mutation; Recombinant Proteins; Serine; Threonine; Tissue Inhibitor of Metalloproteinase-3 | 2002 |
Dependence of control coefficient distribution on the boundaries of a metabolic system: a generalized analysis of the effects of additional input and output reactions to a linear pathway.
Topics: Animals; Cells; Enzymes; Escherichia coli; Mammals; Models, Biological; Serine; Threonine | 2002 |
Serine/threonine phosphorylation of ShcA. Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Insulin; Isoenzymes; Mice; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Proteins; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Threonine | 2002 |
Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant.
Topics: Amino Acid Substitution; Bicarbonates; Binding Sites; Carbon Dioxide; Carbonic Anhydrases; Catalysis; Crystallography, X-Ray; Cysteine; Humans; Mercaptoethanol; Mutagenesis, Site-Directed; Proline; Recombinant Proteins; Serine; Structure-Activity Relationship; Substrate Specificity; Thiocyanates; Threonine; Water | 2002 |
The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation.
Topics: Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Imidazoles; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Up-Regulation | 2002 |
The double-stranded RNA-activated kinase, PKR, can phosphorylate hepatitis D virus small delta antigen at functional serine and threonine residues.
Topics: Cell Line; Cell Nucleolus; DNA, Complementary; eIF-2 Kinase; Gas Chromatography-Mass Spectrometry; Genes, Dominant; Genetic Vectors; HeLa Cells; Hepatitis Antigens; Hepatitis delta Antigens; Humans; Interferon-alpha; Microscopy, Fluorescence; Peptides; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Serine; Threonine; Transfection | 2002 |
Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Antineoplastic Agents, Phytogenic; Butadienes; Cell Line; Enzyme Inhibitors; Gene Expression; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Proteins; Pyridines; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Threonine; Tumor Necrosis Factor-alpha | 2002 |
Structure of the 1-36 N-terminal fragment of human phospholamban phosphorylated at Ser-16 and Thr-17.
Topics: Arginine; Calcium-Binding Proteins; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Phosphorylation; Proline; Protein Conformation; Protein Structure, Tertiary; Serine; Threonine | 2002 |
Flow injection chemiluminescence determination of amino acids by oxidation with N-bromosuccinimide.
Topics: Amino Acids; Anions; Arginine; Bromosuccinimide; Cations; Energy Transfer; Flow Injection Analysis; Glycine; Luminescent Measurements; Oxidation-Reduction; Sensitivity and Specificity; Serine; Threonine | 2002 |
D1 dopamine receptor regulation of microtubule-associated protein-2 phosphorylation in developing cerebral cortical neurons.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Dendrites; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Frontal Lobe; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Neurites; Neurons; Phosphorylation; Receptors, Dopamine D1; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine | 2002 |
Regulation of phospholipase C-gamma1 by protein kinase A-dependent phosphorylation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; COS Cells; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Gene Expression Regulation, Enzymologic; Immunoblotting; Isoenzymes; Ligands; Mice; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Phospholipase C gamma; Phosphorylation; Plasmids; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Rats; Receptors, Adrenergic, beta-2; Serine; Threonine; Time Factors; Transfection; Type C Phospholipases; Tyrosine | 2002 |
Identification of two C-terminal amino acids, Ser(355) and Thr(357), required for short-term homologous desensitization of mu-opioid receptors.
Topics: Alanine; Amino Acid Substitution; Cells, Cultured; Humans; Phosphorylation; Protein Structure, Tertiary; Receptors, Opioid, mu; Serine; Threonine | 2002 |
Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; DNA-Binding Proteins; Fas Ligand Protein; Forkhead Box Protein O3; Forkhead Transcription Factors; Hippocampus; Insulin-Like Growth Factor I; Membrane Glycoproteins; Nerve Tissue Proteins; Neurons; Nitrogen; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Receptor, IGF Type 1; Serine; Signal Transduction; Threonine; Time Factors; Transcription Factors; Transcription, Genetic | 2002 |
Critical roles of phosphorylation and actin binding motifs, but not the central proline-rich region, for Ena/vasodilator-stimulated phosphoprotein (VASP) function during cell migration.
Topics: Actins; Amino Acid Motifs; Animals; Binding Sites; Carrier Proteins; Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Fibroblasts; Genes, Reporter; Genetic Complementation Test; Green Fluorescent Proteins; Indicators and Reagents; Luminescent Proteins; Mice; Microfilament Proteins; Nerve Tissue Proteins; Phenotype; Phosphoproteins; Phosphorylation; Proline; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Serine; Threonine; Vinculin; Wiskott-Aldrich Syndrome Protein, Neuronal | 2002 |
Chicken anemia virus VP2 is a novel dual specificity protein phosphatase.
Topics: Amino Acid Motifs; Amino Acid Sequence; Biochemical Phenomena; Biochemistry; Capsid Proteins; Cloning, Molecular; Cysteine; Genome, Viral; Glutathione Transferase; Kinetics; Molecular Sequence Data; Mutation; Phosphates; Polymerase Chain Reaction; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Vanadates | 2002 |
Ganglioside loss promotes survival primarily by activating integrin-linked kinase/Akt without phosphoinositide 3-OH kinase signaling.
Topics: Apoptosis; bcl-Associated Death Protein; Carcinoma, Squamous Cell; Carrier Proteins; Caspase 9; Caspases; Cell Survival; Cyclin D1; Cyclin E; DNA, Complementary; Fibronectins; G1 Phase; Gangliosides; Humans; Integrin beta1; Keratinocytes; Neuraminidase; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; S Phase; Serine; Signal Transduction; Skin Neoplasms; Threonine; Transfection; Tumor Cells, Cultured | 2002 |
Phosphorylation of beta-arrestin2 regulates its function in internalization of beta(2)-adrenergic receptors.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Arrestins; beta-Arrestins; Casein Kinase II; Cell Line; Clathrin; COS Cells; Down-Regulation; Endocytosis; Humans; Isoproterenol; Phosphorylation; Point Mutation; Protein Binding; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-2; Serine; Threonine; Time Factors | 2002 |
Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cell Adhesion; Cell Division; Cell Line; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; Substrate Specificity; Thiazoles; Thiazolidines; Threonine; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine; Up-Regulation | 2002 |
Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase.
Topics: Animals; Binding Sites; Cell Cycle; Cell Cycle Proteins; Cell Line; Centrosome; Chymotrypsin; Flow Cytometry; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Insecta; Kinetics; Microscopy, Fluorescence; Mitosis; Mutation; Peptides; Phosphorylation; Polo-Like Kinase 1; Precipitin Tests; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; S Phase; Serine; Threonine; Time Factors; Transfection; Xenopus; Xenopus Proteins | 2002 |
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors.
Topics: Animals; Calcineurin; Casein Kinases; Chelating Agents; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cyclosporine; Dopamine and cAMP-Regulated Phosphoprotein 32; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Mice; Neostriatum; Nerve Tissue Proteins; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Kinases; Pyrrolidinones; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Type C Phospholipases | 2002 |
Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress.
Topics: Adenoviridae; Alanine; Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Blotting, Western; Cell Line; Cell Survival; DNA, Complementary; Escherichia coli; Humans; Hydrogen Peroxide; Mice; Mitochondria; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Oxidative Stress; Oxygen; p38 Mitogen-Activated Protein Kinases; Phosphoric Monoester Hydrolases; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 2002 |
Mutational analyses of the signals involved in the subcellular location of DSCR1.
Topics: Amino Acid Motifs; Animals; Calcineurin; Calcineurin Inhibitors; Cell Line; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cyclosporine; DNA-Binding Proteins; Down Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Kidney; Muscle Proteins; Mutagenesis, Site-Directed; Nuclear Proteins; Point Mutation; Proline; Protein Isoforms; Protein Sorting Signals; Serine; src Homology Domains; Tetradecanoylphorbol Acetate; Threonine | 2002 |
Phosphorylation of p85 beta PIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth.
Topics: Animals; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cells, Cultured; Enzyme Activation; Fibroblast Growth Factor 2; Guanine Nucleotide Exchange Factors; Immunoblotting; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Neurons; PC12 Cells; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Transport; Rats; Rho Guanine Nucleotide Exchange Factors; Serine; Signal Transduction; Tetracycline; Threonine; Time Factors; Transfection | 2002 |
Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau.
Topics: Animals; Blotting, Western; Cell Death; Cell Line; Humans; Insecta; Kinetics; Nerve Tissue Proteins; Neurons; Phosphorylation; Plasmids; Protein Binding; Protein Isoforms; Recombinant Proteins; Serine; tau Proteins; Threonine; Time Factors; Trypsin | 2002 |
The carboxyl terminus of peptidoglycan stem peptides is a determinant for methicillin resistance in Staphylococcus aureus.
Topics: Amino Acids; Bacterial Proteins; Carrier Proteins; Chromatography, High Pressure Liquid; Culture Media; Hexosyltransferases; Mass Spectrometry; Methicillin; Methicillin Resistance; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptides; Peptidoglycan; Peptidyl Transferases; Serine; Staphylococcus aureus; Threonine | 2002 |
Disruption of the SHM2 gene, encoding one of two serine hydroxymethyltransferase isoenzymes, reduces the flux from glycine to serine in Ashbya gossypii.
Topics: Amino Acid Sequence; Carbon Radioisotopes; Fungal Proteins; Gene Targeting; Genes, Fungal; Glycine; Glycine Hydroxymethyltransferase; Isoenzymes; Molecular Sequence Data; Promoter Regions, Genetic; Riboflavin; Saccharomycetales; Sequence Alignment; Sequence Analysis, DNA; Serine; Threonine | 2003 |
The relative relevance of phosphorylation of the Thr(17) residue of phospholamban is different at different levels of beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Male; Myocardial Contraction; Myocardium; Phosphorus Radioisotopes; Phosphorylation; Rats; Rats, Wistar; Serine; Sulfonamides; Threonine | 2002 |
The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator.
Topics: Amino Acid Sequence; Amino Acids; Animals; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Glutamic Acid; Humans; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; Mutation; Plasmids; Proline; Proteasome Endopeptidase Complex; Protein Folding; Serine; Threonine; Transfection | 2002 |
Mutations in the putative pore-forming segment favor short-lived wild-type Kir2.1 pore conformations.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Cysteine; Glycosylation; Ion Channel Gating; Isoleucine; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Phenylalanine; Point Mutation; Potassium Channels, Inwardly Rectifying; Protein Conformation; Protein Structure, Tertiary; Serine; Spodoptera; Threonine; Time Factors; Tyrosine | 2002 |
The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin.
Topics: Adaptor Proteins, Signal Transducing; Antibiotics, Antineoplastic; Binding Sites; Carrier Proteins; Cell Cycle Proteins; Cell Line; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Kinetics; Models, Biological; Mutagenesis, Site-Directed; Mutation; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinases; Protein Structure, Tertiary; Recombinant Proteins; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Sirolimus; Substrate Specificity; Threonine; Time Factors; TOR Serine-Threonine Kinases; Transfection | 2002 |
Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta.
Topics: Animals; Brain; Cell Adhesion Molecules, Neuronal; Cell Line; Enzyme Inhibitors; Extracellular Matrix Proteins; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Homozygote; Humans; Immunoblotting; Immunohistochemistry; Mice; Mice, Inbred C57BL; Models, Biological; Nerve Tissue Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Reelin Protein; Serine; Serine Endopeptidases; Signal Transduction; Subcellular Fractions; Threonine; Transfection | 2002 |
Shear stress stimulates phosphorylation of eNOS at Ser(635) by a protein kinase A-dependent mechanism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta, Thoracic; Cattle; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Growth Factors; Endothelium, Vascular; Intercellular Signaling Peptides and Proteins; Lymphokines; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Stress, Mechanical; Threonine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C.
Topics: Animals; Cells, Cultured; Electron Spin Resonance Spectroscopy; Enzyme Induction; Hydrogen Peroxide; Mice; Phosphorylation; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Signal Transduction; Skin; Threonine; TOR Serine-Threonine Kinases; Ultraviolet Rays | 2002 |
Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Binding Sites; Blotting, Western; Carrier Proteins; Cell Survival; DNA, Complementary; Down-Regulation; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Nerve Growth Factor; Neurons; PC12 Cells; Phosphorylation; Plasmids; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Serine; Threonine; Time Factors; Transfection | 2002 |
tRNA-dependent amino acid discrimination by yeast seryl-tRNA synthetase.
Topics: Adenosine Triphosphate; Amino Acids; Electrophoretic Mobility Shift Assay; Escherichia coli; Macromolecular Substances; Protein Binding; RNA, Transfer, Ser; Saccharomyces cerevisiae; Serine; Serine-tRNA Ligase; Substrate Specificity; Threonine | 2002 |
The activity of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is regulated by functional interaction between its two enzyme domains.
Topics: Alanine; Arabidopsis; Aspartic Acid; Casein Kinase II; Chromatography, Gel; Dimerization; Dose-Response Relationship, Drug; Egtazic Acid; Lysine; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; Saccharopine Dehydrogenases; Serine; Sodium Chloride; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2002 |
The stability of the lens-specific Maf protein is regulated by fibroblast growth factor (FGF)/ERK signaling in lens fiber differentiation.
Topics: Animals; Cell Differentiation; Cells, Cultured; Chick Embryo; Cysteine Endopeptidases; delta-Crystallins; Epithelial Cells; Eye Proteins; Fibroblast Growth Factor 2; Gene Expression Regulation, Developmental; Genes, Reporter; Humans; Immunohistochemistry; Lens, Crystalline; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Serine; Threonine; Transcription Factors | 2003 |
Mucin core O-glycosylation is modulated by neighboring residue glycosylation status. Kinetic modeling of the site-specific glycosylation of the apo-porcine submaxillary mucin tandem repeat by UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases T1 an
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Gastric Mucins; Glycosylation; Kinetics; Models, Chemical; Molecular Sequence Data; Mucins; N-Acetylgalactosaminyltransferases; Peptides; Polypeptide N-acetylgalactosaminyltransferase; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Swine; Threonine; Time Factors | 2002 |
Characterization of the O-GlcNAc protein modification in Xenopus laevis oocyte during oogenesis and progesterone-stimulated maturation.
Topics: Acetylglucosamine; Animals; beta-N-Acetylhexosaminidases; Glycosylation; Oocytes; Oogenesis; Progesterone; Proteins; Serine; Signal Transduction; Threonine; Xenopus laevis | 2002 |
Improved system for protein engineering of the hydroxylase component of soluble methane monooxygenase.
Topics: Amino Acid Substitution; Cysteine; Gene Expression; Genetic Vectors; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Oxygenases; Protein Engineering; Protein Subunits; Serine; Solubility; Threonine | 2002 |
Enhanced activity of human N-myristoyltransferase by dimethyl sulfoxide and related solvents in the presence of serine/threonine-containing peptide substrates.
Topics: Acyltransferases; Dimethyl Sulfoxide; Enzyme Activation; Escherichia coli; Humans; Peptides; Serine; Solvents; Substrate Specificity; Threonine | 2002 |
Differential Akt phosphorylation at Ser473 and Thr308 in cultured neurons after exposure to glutamate in rats.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromones; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Glutamic Acid; Glycogen Synthase Kinase 3; In Vitro Techniques; Morpholines; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Threonine; Time Factors | 2002 |
Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.
Topics: Amino Acid Sequence; GTP-Binding Proteins; Humans; Molecular Sequence Data; Phylogeny; Receptors, Cell Surface; Sequence Homology, Amino Acid; Serine; Threonine | 2002 |
Mutations affecting phosphorylation, ubiquitination and turnover of the ABC-transporter Ste6.
Topics: ATP-Binding Cassette Transporters; Base Sequence; DNA Primers; Fluorescent Antibody Technique; Fungal Proteins; Glycoproteins; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Ubiquitin | 2002 |
Mapping sites of O-GlcNAc modification using affinity tags for serine and threonine post-translational modifications.
Topics: Acetylglucosamine; Affinity Labels; Amino Acid Sequence; Animals; Cell Nucleus; Chromatography, Affinity; Chromatography, Liquid; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Lamin B Receptor; Mass Spectrometry; Nuclear Pore Complex Proteins; Peptides; Phosphorylation; Protein Processing, Post-Translational; Rats; Receptors, Cytoplasmic and Nuclear; Reproducibility of Results; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Synapsins; Threonine | 2002 |
Differential phosphorylation of SNAP-25 in vivo by protein kinase C and protein kinase A.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; HeLa Cells; Humans; Kinetics; Membrane Proteins; Nerve Tissue Proteins; Norepinephrine; PC12 Cells; Phosphorylation; Protein Kinase C; Rats; Serine; Synaptosomal-Associated Protein 25; Threonine | 2002 |
On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase.
Topics: Allosteric Regulation; Catalysis; Conserved Sequence; Crystallography, X-Ray; Glycerophosphates; Hydrogen Bonding; Indoles; Kinetics; Ligands; Models, Chemical; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Serine; Stereoisomerism; Structure-Activity Relationship; Threonine; Tryptophan Synthase; Valine | 2002 |
Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Binding Sites; Cell Nucleus; Cells, Cultured; DNA-Binding Proteins; Hepatocyte Nuclear Factor 4; Hepatocytes; Macrophages; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Mutagenesis; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Peptide Mapping; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Rats; Serine; Threonine; Transcription Factors; Transfection | 2003 |
Transcriptional activity of interferon regulatory factor (IRF)-3 depends on multiple protein-protein interactions.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cell Nucleus; Dimerization; DNA; DNA-Binding Proteins; E1A-Associated p300 Protein; Glutathione Transferase; Humans; Interferon Regulatory Factor-3; Mice; Molecular Sequence Data; Mutation; Nuclear Proteins; Phosphorylation; Plasmids; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Threonine; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2002 |
Liddle's syndrome associated with a point mutation in the extracellular domain of the epithelial sodium channel gamma subunit.
Topics: Adult; Amino Acid Sequence; Animals; Asparagine; Base Sequence; Epithelial Sodium Channels; Female; Genes, Dominant; Humans; Hypertension; Hypokalemia; Male; Molecular Sequence Data; Oocytes; Pedigree; Point Mutation; Serine; Sodium Channels; Syndrome; Threonine; Xenopus | 2002 |
Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor.
Topics: Amino Acid Sequence; Animals; Bile Acids and Salts; Binding, Competitive; Biological Transport, Active; Carrier Proteins; Cell Line; CHO Cells; Cricetinae; Cysteine; Humans; Hydroxysteroid Dehydrogenases; Ileum; Kinetics; Membrane Glycoproteins; Mesylates; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Organic Anion Transporters, Sodium-Dependent; Peptide Fragments; Rats; Recombinant Fusion Proteins; Sequence Alignment; Serine; Symporters; Taurocholic Acid; Thiazepines; Threonine; Valine | 2002 |
An expanded V2 receptor retention signal.
Topics: Alanine; Amino Acid Motifs; Cell Line; Cytoplasm; Humans; Ligands; Mutagenesis; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Receptors, Vasopressin; Serine; Signal Transduction; Threonine; Time Factors; Transfection | 2002 |
LXXLL-related motifs in Dax-1 have target specificity for the orphan nuclear receptors Ad4BP/SF-1 and LRH-1.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cells, Cultured; DAX-1 Orphan Nuclear Receptor; DNA-Binding Proteins; Estrogen Receptor alpha; Fushi Tarazu Transcription Factors; Homeodomain Proteins; Mice; Molecular Sequence Data; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Recombinant Proteins; Repressor Proteins; Serine; Steroidogenic Factor 1; Substrate Specificity; Threonine; Transcription Factors; Transcription, Genetic | 2003 |
Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Calcium; COS Cells; Cytoplasm; Drosophila Proteins; Gene Expression Regulation; Glutathione Transferase; Humans; Mass Spectrometry; Models, Biological; Molecular Sequence Data; Nerve Growth Factors; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Fusion Proteins; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Sequence Homology, Amino Acid; Serine; Threonine; Time Factors; Transfection | 2003 |
Site-specific dephosphorylation of endothelial nitric oxide synthase by protein phosphatase 2A: evidence for crosstalk between phosphorylation sites.
Topics: Animals; Cattle; Cell Line; COS Cells; Enzyme Activation; Enzyme Inhibitors; Marine Toxins; Mutagenesis, Site-Directed; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Okadaic Acid; Oxazoles; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Protein Phosphatase 2; Serine; Signal Transduction; Threonine; Transfection | 2002 |
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.
Topics: Amino Acid Sequence; Animals; Apolipoprotein A-I; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Calpain; Cell Line; Cell Membrane; Cells, Cultured; Chickens; Cholesterol; Cross-Linking Reagents; Dipeptides; DNA; Dose-Response Relationship, Drug; Endopeptidases; Glutamic Acid; Hepatocytes; Humans; Ligands; Lipid Metabolism; Macrophages; Mice; Molecular Sequence Data; Phospholipids; Plasmids; Proline; Serine; Threonine; Time Factors; Transfection; Up-Regulation | 2003 |
Polarized absorption spectra of green fluorescent protein single crystals: transition dipole moment directions.
Topics: Amino Acid Substitution; Animals; Crystallization; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; Light; Luminescent Proteins; Microscopy, Fluorescence; Microspectrophotometry; Models, Chemical; Photochemistry; Protons; Scyphozoa; Serine; Spectrometry, Fluorescence; Threonine | 2003 |
Protein engineering of the tissue inhibitor of metalloproteinase 1 (TIMP-1) inhibitory domain. In search of selective matrix metalloproteinase inhibitors.
Topics: Animals; Binding Sites; Catalytic Domain; Genetic Vectors; Humans; Kinetics; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinases; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Structure, Tertiary; Serine; Threonine; Tissue Inhibitor of Metalloproteinase-1; Valine | 2003 |
Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line; Chemokine CCL5; DNA-Binding Proteins; Drosophila Proteins; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Interferon Regulatory Factor-3; Interferon-alpha; Interferon-beta; Lipopolysaccharides; Luciferases; Membrane Glycoproteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Point Mutation; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Double-Stranded; Sendai virus; Serine; Threonine; Time Factors; Toll-Like Receptor 4; Toll-Like Receptors; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured; U937 Cells | 2003 |
Phosphorylation of RGS14 by protein kinase A potentiates its activity toward G alpha i.
Topics: Amino Acid Substitution; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Isoquinolines; Molecular Mimicry; Phosphorylation; Protein Subunits; Proto-Oncogene Proteins; Rats; Recombinant Proteins; RGS Proteins; Serine; Signal Transduction; Sulfonamides; Threonine; Tumor Cells, Cultured | 2003 |
Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Calcium; Humans; Isoenzymes; Mitogen-Activated Protein Kinases; Mitosis; Paclitaxel; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Type C Phospholipases | 2003 |
Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling.
Topics: Amino Acid Sequence; Amino Acid Substitution; beta Catenin; Cells, Cultured; Cytoskeletal Proteins; DNA-Binding Proteins; Down-Regulation; Humans; Intracellular Signaling Peptides and Proteins; Lymphoid Enhancer-Binding Factor 1; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; TCF Transcription Factors; Threonine; Trans-Activators; Transcription Factor 7-Like 2 Protein; Transcription Factors; Two-Hybrid System Techniques; Valine; Wnt Proteins; Zebrafish Proteins | 2003 |
Ab initio conformational space study of model compounds of O-glycosides of serine diamide.
Topics: Computer Simulation; Diamide; Glycopeptides; Glycosides; Hydrogen Bonding; Molecular Conformation; Molecular Structure; Serine; Thermodynamics; Threonine | 2002 |
There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini.
Topics: Amino Acid Sequence; Heterotrimeric GTP-Binding Proteins; Humans; Molecular Sequence Data; Phylogeny; Protein Structure, Tertiary; Receptors, Cell Surface; Sequence Alignment; Serine; Threonine | 2003 |
Fibroblast growth factor-2-induced signaling through lipid raft-associated fibroblast growth factor receptor substrate 2 (FRS2).
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Brain; Detergents; Enzyme Activation; Fibroblast Growth Factor 2; Humans; Lipid Metabolism; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Membrane Microdomains; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Octoxynol; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Serine; Signal Transduction; Threonine; Time Factors; Tumor Cells, Cultured; Tyrosine | 2003 |
Protein-protein interactions between cytochrome b and the Fe-S protein subunits during QH2 oxidation and large-scale domain movement in the bc1 complex.
Topics: Amino Acid Substitution; Catalysis; Cytochrome b Group; Electron Transport; Electron Transport Complex III; Escherichia coli Proteins; Iron-Sulfur Proteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Structure, Tertiary; Protein Subunits; Rhodobacter capsulatus; Serine; Threonine; Ubiquinone | 2003 |
Mitotic regulation of ribosomal S6 kinase 1 involves Ser/Thr, Pro phosphorylation of consensus and non-consensus sites by Cdc2.
Topics: CDC2 Protein Kinase; G2 Phase; HeLa Cells; Humans; Mitosis; Phosphorylation; Proline; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Threonine | 2003 |
Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
Topics: Adenosine Diphosphate; Adolescent; Adult; Benzylamines; Blood Platelets; Clopidogrel; Electrophoresis, Polyacrylamide Gel; Humans; Male; Membrane Proteins; Phosphorylation; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Serine; Signal Transduction; Thiazoles; Thionucleotides; Threonine; Ticlopidine; Tyrosine | 2003 |
Conversion of Ser to Thr residues at the sperm combining-site of mZP3 does not affect sperm receptor activity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Binding Sites; CHO Cells; Cricetinae; Egg Proteins; Female; In Vitro Techniques; Male; Membrane Glycoproteins; Mice; Mutagenesis, Site-Directed; Plasmids; Receptors, Cell Surface; Recombinant Proteins; Serine; Sperm-Ovum Interactions; Threonine; Transfection; Zona Pellucida Glycoproteins | 2003 |
Modulation of cardiac Ca(V)1.2 channels by dihydropyridine and phosphatase inhibitor requires Ser-1142 in the domain III pore loop.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cell Membrane; Cricetinae; Dihydropyridines; Electrophysiology; Enzyme Inhibitors; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rabbits; Serine; Threonine; Time Factors; Transfection | 2003 |
Novel in vitro and in vivo phosphorylation sites on protein phosphatase 1 inhibitor CPI-17.
Topics: Brain; Brain Chemistry; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Humans; Intracellular Signaling Peptides and Proteins; Muscle Proteins; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Phosphatase 1; Serine; Threonine | 2003 |
Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.
Topics: 3T3 Cells; Adenoviridae; Animals; Cell Division; Cell Line; Cloning, Molecular; COS Cells; Enzyme Activation; Fibroblast Growth Factors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Immunoblotting; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Serine; Signal Transduction; Threonine; Thymidine; Tyrosine | 2003 |
Identification of sites of phosphorylation by G-protein-coupled receptor kinase 2 in beta-tubulin.
Topics: Amino Acid Sequence; Animals; beta-Adrenergic Receptor Kinases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Serine; Threonine; Tubulin | 2003 |
Two new mutations in cis on (G)gamma chain of fetal hemoglobin: Hb F-Madrid [G gamma 50(D1)Ser-->Cys] and [G gamma 75(E19)Ile-->Thr].
Topics: Base Sequence; Chromatography, High Pressure Liquid; Cysteine; Female; Fetal Blood; Fetal Hemoglobin; Globins; Hemoglobins, Abnormal; Humans; Infant, Newborn; Isoelectric Focusing; Isoleucine; Male; Mutation; Polymerase Chain Reaction; Serine; Spain; Threonine | 2003 |
Chromium (VI) activates ataxia telangiectasia mutated (ATM) protein. Requirement of ATM for both apoptosis and recovery from terminal growth arrest.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Bromodeoxyuridine; Cell Cycle Proteins; Cell Division; Cell Lineage; Checkpoint Kinase 2; Chromates; Chromium; DNA Damage; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Exons; Fibroblasts; Flow Cytometry; Histones; Homozygote; Humans; Microscopy, Fluorescence; Models, Biological; Phosphatidylserines; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Transport; Serine; Sodium Compounds; Threonine; Time Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2003 |
Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization.
Topics: Agouti-Related Protein; alpha-MSH; Animals; Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestins; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dynamin I; Endocytosis; Enzyme Inhibitors; Gene Expression; Green Fluorescent Proteins; Hemagglutinins; Humans; Hypothalamus, Middle; Indicators and Reagents; Isoquinolines; Kidney; Luminescent Proteins; Mice; Peptide Fragments; Phosphorylation; Receptor, Melanocortin, Type 4; Receptors, Corticotropin; Serine; Signal Transduction; Sulfonamides; Threonine | 2003 |
Function of the loop residue Thr792 in human DNA topoisomerase II alpha.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Catalysis; Cell Division; Cysteine; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Fungal Proteins; Genetic Complementation Test; Glutamic Acid; Glycine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Poly-ADP-Ribose Binding Proteins; Saccharomyces cerevisiae; Serine; Threonine; Valine | 2003 |
Structure-function studies of the C3a-receptor: C-terminal serine and threonine residues which influence receptor internalization and signaling.
Topics: Animals; Calcium; Cell Line; Endocytosis; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Kinetics; Membrane Proteins; Mutation; Rats; Receptors, Complement; Serine; Signal Transduction; Structure-Activity Relationship; Threonine | 2003 |
Endocytosis of the AT1A angiotensin receptor is independent of ubiquitylation of its cytoplasmic serine/threonine-rich region.
Topics: Amino Acid Sequence; Angiotensin II; Animals; CHO Cells; Cricetinae; Endocytosis; Molecular Sequence Data; Mutagenesis; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Serine; Threonine; Ubiquitin | 2003 |
A serine/threonine phosphorylation site in the ectodomain of a T cell receptor beta chain is required for activation by superantigen.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Binding Sites; CD3 Complex; Cell Line; DNA, Complementary; Enterotoxins; Hybridomas; In Vitro Techniques; Interleukin-2; Mice; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Receptors, Antigen, T-Cell, alpha-beta; Serine; Superantigens; T-Lymphocytes; Threonine | 2003 |
Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; 3T3 Cells; Actins; Adipocytes; Animals; Binding Sites; Cell Adhesion; Cell Line; Cell Membrane; Cell-Free System; Cytoskeleton; Cytosol; Glutathione Transferase; Humans; Immunoblotting; Mice; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Subcellular Fractions; Substrate Specificity; Temperature; Threonine; Time Factors | 2003 |
Reconstitution of phosphoinositide 3-kinase-dependent insulin signaling in a cell-free system.
Topics: 3T3 Cells; Adipocytes; Androstadienes; Animals; Cell Membrane; Cell-Free System; Cytosol; Glutathione Transferase; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Recombinant Fusion Proteins; Serine; Signal Transduction; Subcellular Fractions; Threonine; Time Factors; Wortmannin | 2003 |
Phosphorylation of phosphatase inhibitor-2 at centrosomes during mitosis.
Topics: Amino Acid Sequence; Cell Cycle; Centrosome; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; HeLa Cells; Humans; Immunoblotting; Immunohistochemistry; Mass Spectrometry; Microscopy, Fluorescence; Mitosis; Molecular Sequence Data; Nocodazole; Phosphorylation; Protein Binding; Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Threonine | 2003 |
Stoichiometry of site-specific protein phosphorylation estimated with phosphopeptide-specific antibodies.
Topics: Antibodies; Binding Sites; Phosphopeptides; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Subunits; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2003 |
Practical synthesis of the 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D-glucosides of Fmoc-serine and Fmoc-threonine and their benzyl esters.
Topics: Benzene; Bromides; Carboxylic Acids; Esters; Ethylene Dichlorides; Glucosides; Glycosylation; Mercury; Molecular Structure; Serine; Threonine | 2003 |
Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Antineoplastic Agents; Cells, Cultured; Humans; Immunosuppressive Agents; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Mutation; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Proline; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Signal Transduction; Sirolimus; Threonine; Transfection; Wortmannin | 2003 |
Cdc2-mediated phosphorylation of Kid controls its distribution to spindle and chromosomes.
Topics: Bacterial Proteins; Bacterial Toxins; Base Sequence; CDC2 Protein Kinase; Chromosome Mapping; DNA Primers; HeLa Cells; Humans; Phosphorylation; Serine; Threonine | 2003 |
Glutamate substitutions at a PKA consensus site are consistent with inactivation of calpain by phosphorylation.
Topics: Amino Acid Substitution; Animals; Calcium; Calpain; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; Enzyme Stability; Glutamic Acid; Mutation; Phosphorylation; Rats; Serine; Threonine | 2003 |
A glycosylation site, 60SGTS63, of p67 is required for its ability to regulate the phosphorylation and activity of eukaryotic initiation factor 2alpha.
Topics: Acetylglucosaminidase; Amino Acid Substitution; Aminopeptidases; Animals; Blotting, Western; Carcinoma, Hepatocellular; DNA Primers; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Gene Expression Regulation; Glutathione Transferase; Glycoproteins; Glycosylation; Green Fluorescent Proteins; Liver Neoplasms; Luminescent Proteins; Methionine; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Polymerase Chain Reaction; Precipitin Tests; Protein Conformation; Rats; Recombinant Fusion Proteins; Serine; Threonine; Tumor Cells, Cultured | 2003 |
Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; cdc25 Phosphatases; Cell Cycle Proteins; G1 Phase; Glutathione Transferase; HeLa Cells; Humans; Membrane Proteins; Mitosis; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Phosphorylation; Polo-Like Kinase 1; Precipitin Tests; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Sequence Homology, Amino Acid; Serine; Threonine; Transfection; Xenopus; Xenopus Proteins | 2003 |
Glucose-induced stimulation of the Ras-cAMP pathway in yeast leads to multiple phosphorylations and activation of 6-phosphofructo-2-kinase.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Fungal Proteins; Glucose; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phosphofructokinase-2; Phosphorylation; ras Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Deletion; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2003 |
Two Hyposoter didmator ichnovirus genes expressed in the lepidopteran host encode secreted or membrane-associated serine and threonine rich proteins in segments that may be nested.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; DNA Primers; DNA, Viral; Genes, Viral; Lepidoptera; Molecular Sequence Data; Polydnaviridae; Polymerase Chain Reaction; Sequence Homology, Nucleic Acid; Serine; Threonine; Viral Proteins | 2003 |
Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters.
Topics: Agrin; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Chickens; Chondroitin Sulfates; Electrophoresis, Polyacrylamide Gel; Glycine; Glycosylation; Heparitin Sulfate; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Plasmids; Protein Structure, Tertiary; Proteoglycans; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Threonine | 2003 |
Mutations in the PDS gene in German families with Pendred's syndrome: V138F is a founder mutation.
Topics: Adolescent; Amino Acid Substitution; Base Sequence; Carrier Proteins; Child; Child, Preschool; Female; Founder Effect; Germany; Haplotypes; Hearing Loss, Sensorineural; Humans; Hypothyroidism; Infant, Newborn; Male; Membrane Transport Proteins; Mutation, Missense; Pedigree; Serine; Sulfate Transporters; Syndrome; Threonine; Turkey | 2003 |
Synergistic growth inhibitory effects of interferon-alpha and lovastatin on bcr-abl positive leukemic cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Fusion Proteins, bcr-abl; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon alpha-2; Interferon-alpha; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lovastatin; Mevalonic Acid; Phosphorylation; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Serine; Threonine; Time Factors; Tyrosine | 2003 |
Phenotype of retinitis pigmentosa associated with the Ser50Thr mutation in the NRL gene.
Topics: Adolescent; Adult; Basic-Leucine Zipper Transcription Factors; Child; Dark Adaptation; DNA-Binding Proteins; Electroretinography; Eye Proteins; Female; Fluorescein Angiography; Humans; Leucine Zippers; Male; Middle Aged; Mutation; Night Blindness; Ophthalmoscopy; Pedigree; Phenotype; Photoreceptor Cells, Vertebrate; Retinitis Pigmentosa; Serine; Threonine; Transcription Factors; Visual Acuity; Visual Fields | 2003 |
Functional correlates of mutations in beta-catenin exon 3 phosphorylation sites.
Topics: Animals; beta Catenin; Cell Line; COS Cells; Cytoskeletal Proteins; Dogs; Exons; I-kappa B Kinase; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine; Trans-Activators | 2003 |
Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation.
Topics: Bacteria; Catalytic Domain; Checkpoint Kinase 2; Enzyme Activation; Genetic Complementation Test; HeLa Cells; Humans; Mutagenesis, Site-Directed; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine | 2003 |
Mutational analysis of the human FATE gene in 144 infertile men.
Topics: Adult; Alanine; Amino Acid Sequence; Animals; Arginine; Cysteine; DNA Mutational Analysis; DNA Primers; DNA-Binding Proteins; Exons; Humans; Infertility, Male; Introns; Karyotyping; Male; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction; Polymorphism, Genetic; Serine; Threonine; Transcription Factors; X Chromosome | 2003 |
Identification of a site in GluR1 and GluR2 that is important for modulation of deactivation and desensitization.
Topics: Amino Acid Substitution; Animals; Benzothiadiazines; Binding Sites; Dioxoles; Glutamic Acid; Kinetics; Models, Molecular; Oocytes; Piperidines; Point Mutation; Receptors, AMPA; Serine; Threonine; Transfection; Xenopus laevis | 2003 |
Spectrum of CBS mutations in 16 homocystinuric patients from the Iberian Peninsula: high prevalence of T191M and absence of I278T or G307S.
Topics: Adolescent; Adult; Amino Acid Sequence; Amino Acid Substitution; Animals; Child; Child, Preschool; Cystathionine beta-Synthase; Female; Genotype; Glycine; Homocystinuria; Humans; Infant; Isoleucine; Male; Methionine; Middle Aged; Molecular Sequence Data; Phenotype; Portugal; Prevalence; Serine; Spain; Threonine | 2003 |
The role of two novel regulatory sites in the activation of the cGMP-dependent protein kinase from Plasmodium falciparum.
Topics: Alanine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Conserved Sequence; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Gene Duplication; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Recombinant Proteins; Serine; Thionucleotides; Threonine | 2003 |
Identifying protein kinase C substrates: an introduction.
Topics: Isoenzymes; Protein Kinase C; Serine; Substrate Specificity; Threonine | 2003 |
Mass spectrometry and site-directed mutagenesis identify several autophosphorylated residues required for the activity of PrkC, a Ser/Thr kinase from Bacillus subtilis.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Bacillus subtilis; Bacterial Proteins; Binding Sites; Chromatography, High Pressure Liquid; Escherichia coli; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Myelin Basic Protein; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Structure-Activity Relationship; Threonine | 2003 |
JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun.
Topics: 3T3 Cells; Animals; Cell Line; Genes, Reporter; Histone Deacetylases; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; RNA, Messenger; Sequence Deletion; Serine; Suppression, Genetic; Threonine; Transcription, Genetic; Transcriptional Activation | 2003 |
Requirement for 3-phosphoinositide-kependent dinase-1 (PDK-1) in insulin-induced glucose uptake in immortalized brown adipocytes.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adenoviridae; Adipocytes; Adipose Tissue, Brown; Aminoimidazole Carboxamide; Animals; Biological Transport; Cell Differentiation; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Gene Deletion; Gene Transfer Techniques; Genetic Vectors; Glucose; Glucose Transporter Type 4; Heterozygote; Immunohistochemistry; Insulin; Integrases; MAP Kinase Signaling System; Mice; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Muscle Proteins; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribonucleotides; Serine; Signal Transduction; Threonine; Viral Proteins | 2003 |
Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint.
Topics: Animals; Antineoplastic Agents; Cdc20 Proteins; Cell Cycle Proteins; Genes, cdc; Mitogen-Activated Protein Kinases; Mitosis; Models, Biological; Nocodazole; Oocytes; Phosphorylation; Saccharomyces cerevisiae Proteins; Serine; Spindle Apparatus; Threonine; Xenopus laevis | 2003 |
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Brain; Cell Cycle; Cell Line; Cell Nucleus; Chromosome Mapping; Cytosol; DNA Repair; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Green Fluorescent Proteins; Humans; In Situ Hybridization; Insulin; Luciferases; Luminescent Proteins; Mice; Mice, Inbred C57BL; Models, Genetic; Molecular Sequence Data; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Biosynthesis; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine; Time Factors; Tissue Distribution; Transcription Factors; Transfection | 2003 |
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells.
Topics: Acetylcysteine; Angiotensin II; Animals; Aorta; Azoles; Blotting, Western; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Genes, Dominant; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoindoles; Muscle, Smooth, Vascular; Okadaic Acid; Onium Compounds; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Pyridines; Rats; Reactive Oxygen Species; Serine; Threonine; Time Factors | 2003 |
Frequent beta-catenin alteration in gallbladder carcinomas.
Topics: Adult; Aged; beta Catenin; Binding Sites; Cell Differentiation; Cytoskeletal Proteins; DNA; DNA Mutational Analysis; Female; Gallbladder Neoplasms; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunohistochemistry; Male; Middle Aged; Mutation; Phosphorylation; Polymorphism, Single-Stranded Conformational; Serine; Signal Transduction; Threonine; Trans-Activators | 2003 |
Mucin production and composition is altered in dextran sulfate sodium-induced colitis in rats.
Topics: Animals; Dextran Sulfate; Enterocolitis; Goblet Cells; Intestines; Male; Models, Animal; Mucins; Rats; Rats, Sprague-Dawley; Serine; Threonine | 2003 |
A chemical approach for identifying O-GlcNAc-modified proteins in cells.
Topics: Acetylglucosamine; Blotting, Western; Cell Nucleus; Cloning, Molecular; Cytoplasm; Dose-Response Relationship, Drug; Glycosylation; Hexosamines; Humans; Jurkat Cells; Kinetics; Models, Chemical; Nuclear Pore; Phosphotransferases (Phosphomutases); Precipitin Tests; Protein Processing, Post-Translational; Proteins; Recombinant Proteins; Serine; Substrate Specificity; Threonine; Tumor Cells, Cultured | 2003 |
Efficiency of a cysteine-taurine-threonine-serine supplemented parenteral nutrition in an experimental model of acute inflammation.
Topics: Acute Disease; Animals; Cysteine; Dietary Supplements; Inflammation; Male; Parenteral Nutrition; Prospective Studies; Rats; Rats, Sprague-Dawley; Serine; Taurine; Threonine | 2003 |
A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun.
Topics: Amino Acid Sequence; Animals; Anisomycin; Antibodies; Cell Line; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Proto-Oncogene Proteins c-jun; Serine; Threonine | 2003 |
Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster.
Topics: Alcohols; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Butanols; Crystallography, X-Ray; Drosophila melanogaster; Hydrogen Bonding; Ions; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Receptors, Odorant; Serine; Threonine | 2003 |
Thin layer chromatographic resolution of some 2-arylpropionic acid enantiomers using L-(-)-serine, L-(-)-threonine and a mixture of L-(-)-serine and L-(-)-threonine-impregnated silica gel as stationary phases.
Topics: Chromatography, Thin Layer; Gels; Hydrogen-Ion Concentration; Molecular Structure; Phenylpropionates; Serine; Silicon Dioxide; Solvents; Stereoisomerism; Structure-Activity Relationship; Temperature; Threonine | 2003 |
Adhesion-associated and PKC-modulated changes in serine/threonine phosphorylation of p120-catenin.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Catenins; Cell Adhesion; Cell Adhesion Molecules; Cell Membrane Permeability; Conserved Sequence; Delta Catenin; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoamino Acids; Phosphoproteins; Phosphorylation; Protein Kinase C; Serine; Signal Transduction; Species Specificity; Staurosporine; Substrate Specificity; Threonine; Tumor Cells, Cultured | 2003 |
Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Blotting, Western; CHO Cells; Cricetinae; Dimerization; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Insulin; Mice; Models, Genetic; Mutagenesis, Site-Directed; Phosphoamino Acids; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Threonine | 2003 |
Protein PknE, a novel transmembrane eukaryotic-like serine/threonine kinase from Mycobacterium tuberculosis.
Topics: Amino Acid Motifs; Catalytic Domain; Cell Membrane; Cytoplasm; Cytosol; Glutathione Transferase; Lysine; Models, Genetic; Mutagenesis, Site-Directed; Mutation; Mycobacterium tuberculosis; Phosphorylation; Plasmids; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine | 2003 |
Serine acetyltransferase of Escherichia coli: substrate specificity and feedback control by cysteine.
Topics: Acetyl Coenzyme A; Acetyltransferases; Acyl Coenzyme A; Adenosine Triphosphate; Calorimetry; Cysteine; Escherichia coli; Feedback, Physiological; Glycine; Kinetics; Serine; Serine O-Acetyltransferase; Substrate Specificity; Threonine | 2003 |
Roles of Ser130 and Thr126 in chloride binding and photocycle of pharaonis halorhodopsin.
Topics: Absorption; Amino Acid Substitution; Chlorides; Escherichia coli; Halorhodopsins; Kinetics; Models, Molecular; Natronobacterium; Periodicity; Photochemistry; Protein Binding; Protein Conformation; Recombinant Proteins; Serine; Spectrophotometry; Threonine | 2003 |
Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin.
Topics: Alanine; Amino Acid Motifs; Collagen; Hydrogen Bonding; Integrin alpha1beta1; Integrins; Magnetic Resonance Spectroscopy; Models, Molecular; Models, Statistical; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Threonine; Viper Venoms | 2003 |
Phosphorylation of serine 337 of NF-kappaB p50 is critical for DNA binding.
Topics: Animals; Binding Sites; Blotting, Western; Cell Line; COS Cells; Cyclic AMP-Dependent Protein Kinases; Dimerization; DNA; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Models, Molecular; Mutagenesis, Site-Directed; NF-kappa B; NF-kappa B p50 Subunit; Phosphorylation; Plasmids; Protein Binding; Protein Biosynthesis; Serine; Threonine; Transcription Factor RelA; Transcription, Genetic; Transfection | 2003 |
Identification of two serine residues essential for agonist-induced 5-HT2A receptor desensitization.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cells, Cultured; Enzyme Inhibitors; Humans; Molecular Sequence Data; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Quipazine; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Recombinant Proteins; Serine; Serotonin; Serotonin Receptor Agonists; Threonine; Transfection | 2003 |
EGFR and FGFR signaling through FRS2 is subject to negative feedback control by ERK1/2.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; COS Cells; ErbB Receptors; Feedback, Physiological; Humans; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Binding; Receptors, Fibroblast Growth Factor; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Threonine; Tyrosine | 2003 |
The lipotropic action of threonine and related substances in the rat.
Topics: Amino Acids; Animals; Lipotropic Agents; Liver; Rats; Serine; Threonine | 1953 |
Some aspects of threonine and serine biosynthesis in E. coli.
Topics: Biochemical Phenomena; Escherichia coli; Serine; Threonine | 1953 |
Preparation and properties of 3-phenyl-2-thiohydantoins of serine, threonine and cystine.
Topics: Cystine; Hydantoins; Serine; Thiohydantoins; Threonine | 1955 |
The fermentation of L-threonine, L-serine, L-cysteine and acrylic acid by a gram-negative coccus.
Topics: Acids; Acrylates; Bacteria; Cysteine; Fermentation; Gram-Negative Bacteria; Serine; Threonine | 1955 |
Pyridoxal and metal ion catalysis of alpha, beta elimination reactions of serine-3-phosphate and related compounds.
Topics: Biological Transport; Catalysis; Metals; Phosphates; Phosphoserine; Pyridoxal; Serine; Threonine; Vitamin B 6 | 1957 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
The amino acid requirements of rabbit fibroblasts, strain RM3-56.
Topics: Alanine; Amino Acids; Animals; Arginine; Cystine; Fibroblasts; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rabbits; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
O-sulphate esters of L-serine, L-threonine and L-hydroxyproline.
Topics: Amino Acids; Esters; Hydroxyproline; Proline; Serine; Sulfates; Threonine | 1961 |
[Contributions to silkworm biochemistry. XVI. Conversion of threonine into the glycine, serine and alanine of silk fibroin].
Topics: Alanine; Amino Acids; Animals; Bombyx; Fibroins; Glycine; Insecta; Proteins; Serine; Silk; Threonine | 1960 |
The influence of folic acid, threonine and glycine on serine synthesis in Tetrahymena.
Topics: Amino Acids; Folic Acid; Glycine; Humans; Serine; Tetrahymena; Threonine | 1960 |
Mechanism of enzymic formation of threonine from O-phosphohomoserine.
Topics: Amino Acids; Biochemical Phenomena; Homoserine; Serine; Threonine | 1959 |
Studies on the biosynthesis of prophyrin and bacteriochlorophyll by Rhodoseudomonas spheroides. 3. The effect of threonine on the biosynthesis of homoserine and methionine.
Topics: Amino Acids; Bacteriochlorophylls; Homoserine; Methionine; Rhodopseudomonas; Serine; Threonine | 1962 |
Studies on the nature, inducibility, and assay of the threonine and serine dehydrase activities of rat liver.
Topics: Biological Assay; Hydro-Lyases; Liver; Serine; Threonine | 1962 |
[A new decomposition of serine and threonine by chloramine-T and periodate mixture].
Topics: Amino Acids; Anti-Infective Agents, Local; Chloramines; Halogens; Hydrocarbons, Halogenated; Periodic Acid; Serine; Threonine; Tosyl Compounds | 1962 |
Effect of cultural conditions on growth and metabolite uptake by serine-glycine auxotrophs of Escherichia coli.
Topics: Amino Acids; Asparagine; Biological Transport; Escherichia coli; Glycine; Homoserine; Serine; Threonine | 1962 |
Amino acids, amino sugars and sugars present in the cell wall of some strains of Streptococcus pyogenes.
Topics: Alanine; Amino Acids; Amino Sugars; Arginine; Aspartic Acid; Cell Wall; Cysteine; Glucosamine; Glutamates; Glycine; Hexosamines; Isoleucine; Leucine; Lysine; Serine; Streptococcus pyogenes; Threonine; Valine | 1962 |
[On amino acid metabolism in blood diseases with special reference to aplastic anemia].
Topics: Alanine; Amino Acids; Anemia; Anemia, Aplastic; Glutamates; Glycine; Humans; Hydroxyproline; Serine; Threonine | 1962 |
Nematode biochemistry. II. Biosynthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Nematoda; Serine; Threonine; Tyrosine; Valine | 1962 |
[o-Dinitrophenyl-D,L-serine, o-dinitrophenyl-D,L-threonine and o-dinitrophenyl-D,L-allo-threonine and their conversion to the N-dinitrophenyl derivatives].
Topics: Amino Acids; Dinitrobenzenes; Serine; Threonine | 1961 |
Metabolic adaptations in rat hepatomas. IV. Regulation of threonine and serine dehydrase.
Topics: Animals; Carcinoma, Hepatocellular; Dietary Proteins; Hydro-Lyases; Liver Neoplasms; Oxidoreductases; Rats; Serine; Threonine | 1963 |
Amino acid dependent control of DNA synthesis in bacteria and vegetative phage.
Topics: Amino Acids; Arginine; Coliphages; Cysteine; DNA; DNA, Bacterial; Escherichia coli; Histidine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan | 1962 |
GENE TRANSFER BY F' STRAINS OF ESCHERICHIA COLI K-12. II. INTERACTION BETWEEN F-MEROGENOTE AND CHROMOSOME DURING TRANSFER.
Topics: Chromosomes; Escherichia coli; Escherichia coli K12; Galactose; Histidine; Isoleucine; Lactose; Leucine; Maltose; Mannitol; Methionine; Proline; Research; Serine; Streptomycin; Thiamine; Threonine; Tryptophan; Valine; Xylose | 1963 |
[MECHANISMS OF AMINO ACID SYNTHESIS IN LEAVES. STUDIES USING RADIOCARBON].
Topics: Alanine; Amino Acids; Aminobutyrates; Ammonium Compounds; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chromatography; Darkness; Glutamates; Glutamine; Glycine; Light; Methionine; Nitrates; Plant Proteins; Proteins; Quaternary Ammonium Compounds; Research; Serine; Threonine | 1963 |
[SIDE-CHAIN RECIPROCAL ACTION IN SERINE- OR THREONINE-CONTAINING ASPARAGYL PEPTIDES].
Topics: Aspartic Acid; Glutamates; Peptides; Serine; Threonine | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
GAS CHROMATOGRAPHY OF AMINO ACIDS. 1. ANALYSIS OF THE MIXTURE OF METHYL-NTRIFLUOROACETYL DERIVATIVES.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Chromatography, Gas; Fluoroacetates; Glutamates; Glycine; Hydroxyproline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
THE NH2-TERMINAL RESIDUES OF THE PROTEINS FROM CELL-FREE EXTRACTS OF E. COLI.
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Chromatography; Electrophoresis; Escherichia coli; Glutamates; Methionine; Phenytoin; Proteins; Research; Serine; Threonine | 1963 |
EFFECT OF O-METHYL-DL-THREONINE AND O-METHYL-DL-SERINE ON GROWTH AND PROTEIN SYNTHESIS IN ESCHERICHIA COLI.
Topics: Alkaline Phosphatase; Amino Acids; Bacterial Proteins; beta-Galactosidase; Carbon Isotopes; Escherichia coli; Galactosidases; Methionine; Proteins; Research; Serine; Threonine | 1963 |
EFFECT OF ALANINE AND THREONINE ON THE SYNTHESIS OF SERINE BY LEUCONOSTOC MESENTEROIDES.
Topics: Alanine; Amino Acids; Bacterial Proteins; Benzoates; Formates; Glutamine; Glycine; Histidine; Leuconostoc; Leucovorin; Proteins; Research; Serine; Threonine | 1963 |
THE INHIBITION OF CEREBRAL DIGLYCINASE BY ALPHA-AMINO-, ALPHA-KETO- AND ALPHA-HYDROXY ACIDS.
Topics: Alanine; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cobalt; Enzyme Inhibitors; Histidine; Hydroxy Acids; Keto Acids; Leucine; Methionine; Mice; Peptide Hydrolases; Peptides; Pharmacology; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Valine | 1963 |
OXIDATION OF L-AMINO ACIDS AND INCORPORATION INTO PROTEIN IN HOMOGENATES OF BRAIN AT TWO STAGES OF DEVELOPMENT.
Topics: Alanine; Amino Acids; Arginine; Autoradiography; Brain; Carbon Isotopes; Chromatography; Glycine; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Mice; Nerve Tissue Proteins; Phenylalanine; Proline; Proteins; Pyruvates; Research; Serine; Threonine; Valine | 1963 |
THE EFFECT OF AMINO ACIDS ON THE PAPER ELECTROPHORESIS OF THYROXINE AND TRIIODOTHYRONINE.
Topics: Amino Acids; Blood Proteins; Electrophoresis; Electrophoresis, Paper; Hydrogen-Ion Concentration; Iodine Isotopes; Pharmacology; Phenylalanine; Research; Serine; Threonine; Thyroxine; Triiodothyronine; Trypsin | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine | 1963 |
EFFECTS OF FEEDBACK MODIFIERS ON THE STATE OF AGGREGATION OF HOMOSERINE DEHYDROGENASE OF RHODOSPIRILLUM RUBRUM.
Topics: Chemical Phenomena; Chemistry; Enzyme Inhibitors; Homoserine Dehydrogenase; Isoleucine; Methionine; Oxidoreductases; Research; Rhodospirillum; Rhodospirillum rubrum; Serine; Threonine | 1964 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
THE SUBMOLAR QUANTITIES OF N-TERMINALS IN PROTEINS. EFFECT OF SODIUM DODECYL SULFATE ON THE N-TERMINALS OF EGG ALBUMIN AND BOVINE, EQUINE, AND PORCINE GAMMA-GLOBULINS.
Topics: Alanine; Albumins; Animals; Cattle; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Horses; Ovalbumin; Proteins; Research; Serine; Sodium Dodecyl Sulfate; Surface-Active Agents; Swine; Threonine; Trypsin | 1964 |
A DETERMINATION OF THE ESSENTIAL AMINO ACID PROPORTIONS NEEDED TO ALLOW RAPID GROWTH IN CHICKS.
Topics: Amino Acids; Amino Acids, Essential; Animals; Animals, Newborn; Arginine; Caseins; Chickens; Cystine; Diet; Dietary Proteins; Glutamates; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Poultry; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
RELATIVE POTENCY OF DIETS CONTAINING AMINO ACIDS AND PROTEINS FOR PROMOTING GROWTH OF RATS.
Topics: Albumins; Amino Acids; Animals, Newborn; Arginine; Cystine; Diet; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proteins; Rats; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE CHEMICAL COMPOSITION OF THE CELL WALL OF THE YEAST, NADSONIA ELONGATA.
Topics: Aspartic Acid; Carbohydrates; Carbon Isotopes; Cell Biology; Cell Wall; Centrifugation; Chemical Phenomena; Chemistry; Chromatography; Fatty Acids; Glucosamine; Glycine; Mannose; Nitrogen; Phosphorus; Plant Proteins; Research; Serine; Sodium Chloride; Threonine; Yeasts | 1964 |
THE INCORPORATION OF LABELLED CO2 INTO CELLS AND EXTRACTS OF NITROSOMONAS EUROPAEA.
Topics: Adenosine Triphosphate; Alanine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Glycine; Heptoses; Hexoses; Metabolism; NAD; Nitrosomonas; Nitrosomonas europaea; Phosphates; Pyruvates; Research; Serine; Threonine | 1964 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine | 1964 |
POLYNUCLEOTIDE ANALOGUES. II. STIMULATION OF AMINO ACID INCORPORATION BY POLYNUCLEOTIDE ANALOGUES.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Glycine; Isoleucine; Leucine; Lysine; Pharmacology; Phenylalanine; Polynucleotides; Proline; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Uracil Nucleotides; Valine | 1964 |
MIGRATION OF AMINO ACIDS ACROSS THE MEMBRANE OF THE HUMAN ERYTHROCYTE.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Carbon Isotopes; Erythrocytes; Glycine; Histidine; Leucine; Methionine; Permeability; Phenylalanine; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
EFFECT OF INSULIN ON ACCUMULATION OF RADIOACTIVITY FROM AMINO-ACIDS BY ISOLATED INTACT RAT DIAPHRAGM.
Topics: Amino Acids; Arginine; Biological Transport; Carbon Isotopes; Cystine; Diaphragm; Hydroxyproline; Insulin; Isoleucine; Leucine; Muscles; Permeability; Pharmacology; Proteins; Radioactivity; Rats; Research; Serine; Threonine; Tryptophan | 1964 |
THE INHIBITION OF MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE. 2. THE EFFECTS OF AMINO ACIDS AND SUGARS.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Enzyme Inhibitors; Fructose; Glutamates; Glycine; Histidine; Hydroxyproline; Isoleucine; Lactose; Liver; Lysine; Methionine; Mitochondria; Oligosaccharides; Pharmacology; Proline; Rats; Research; Serine; Threonine; Valine | 1964 |
AMINO ACID METABOLISM IN RAT BRAIN STUDIED WITH 14C-LABELLED GLUCOSE.
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamates; Glutamine; Glycine; Lead; Nitrophenols; Proteins; Rats; Research; Seizures; Serine; Threonine; Tin; Toxicology | 1964 |
CHROMATOGRAPHIC SEPARATION OF PYRIDOXYL DERIVATIVES OF AMINO ACIDS.
Topics: Alanine; Amines; Amino Acids; Arginine; Aspartic Acid; Chromatography; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Phenylalanine; Pyridines; Pyridoxine; Research; Serine; Threonine; Tyrosine; Valine | 1964 |
SERUM AMINO ACIDS IN KWASHIORKOR. I. RELATIONSHIP TO CLINICAL CONDITION.
Topics: Alanine; Amino Acids; Biomedical Research; Black People; Blood; Glutamates; Glutamine; Glycine; Infant; Isoleucine; Kwashiorkor; Leucine; Methionine; Phenylalanine; Serine; Threonine; Tyrosine; Uganda; Valine | 1964 |
SERINE DEAMINATION BY THE B PROTEIN OF ESCHERICHIA COLI TRYPTOPHAN SYNTHETASE.
Topics: Bacterial Proteins; Chromatography; Deamination; Electrophoresis; Enzyme Inhibitors; Escherichia coli; Glycerophosphates; Hydro-Lyases; Indoles; Ligases; Membrane Glycoproteins; Oxidoreductases; Pyridoxal Phosphate; Research; Serine; Spectrophotometry; Threonine; Tryptophan; Tryptophan Synthase | 1964 |
[FREE AMINO ACIDS IN THE BLOOD AND URINE OF PATIENTS WITH SOME FORMS OF DERMATOSIS].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Blood; Cystine; Dermatitis; Eczema; Erythema Multiforme; Glutamates; Glycine; Histidine; Lupus Erythematosus, Systemic; Lysine; Proteins; Psoriasis; Renal Aminoacidurias; Serine; Skin Diseases; Taurine; Threonine; Toxicology; Tryptophan; Urticaria | 1964 |
THE SYNTHESIS OF 6-O-CARBAMYL-L-SERINE, 6-D-SERINE, AND 6-L-THREONINE BRADYKININ.
Topics: Animals; Blood Pressure; Bradykinin; Bronchi; Chemistry, Pharmaceutical; Guinea Pigs; Peptides; Pharmacology; Research; Serine; Threonine | 1963 |
THE ENZYMATIC SYNTHESIS OF D-ALANYL-D-ALANINE. 3. ON THE INHIBITION OF D-ALANYL-D-ALANINE SYNTHETASE BY THE ANTIBIOTIC D-CYCLOSERINE.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Anti-Bacterial Agents; Carbon Isotopes; Chromatography; Cycloserine; Enterococcus faecalis; Enzyme Inhibitors; Ligases; Magnesium; Oxazoles; Pharmacology; Potassium; Research; Serine; Threonine | 1964 |
[EFFECTOR-EFFECTOR COOPERATIVE INTERACTIONS IN 2 ALLOSTERIC ENZYMES INHIBITED IN A NONCOMPETETIVE MANNER].
Topics: Alcohol Oxidoreductases; Biochemical Phenomena; Biochemistry; Lysine; Phosphotransferases; Research; Serine; Threonine | 1964 |
INOTROPIC ACTIVITY OF A SERIES OF AMINO ACIDS.
Topics: Adrenal Glands; Alanine; Amino Acids; Blood Pressure; Cysteine; Dogs; Glycine; Heart; Leucine; Methionine; Pharmacology; Research; Sensory Receptor Cells; Serine; Threonine | 1964 |
[FREE PLASMA AMINO ACIDS IN LIVER CIRRHOSIS AND HEPATITIS].
Topics: Alanine; Amino Acids; Blood; Chromatography; Glutamine; Glycine; Hepatitis; Humans; Ion Exchange Resins; Liver Cirrhosis; Methionine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine | 1964 |
DISTRIBUTION AND METABOLISM OF THREONINE ETHANOLAMINE AND SERINE ETHANOLAMINE PHOSPHODIESTERS IN NERVOUS TISSUES.
Topics: Amino Alcohols; Animals; Biological Evolution; Brain Chemistry; Eels; Ethanolamine; Ethanolamines; Fishes; Nerve Tissue; Phosphates; Phosphatidylethanolamines; Phosphoric Monoester Hydrolases; Phosphoserine; Physiology, Comparative; Research; Serine; Species Specificity; Spinal Cord; Threonine | 1964 |
MYOGLOBIN FREE-RADICALS.
Topics: Alanine; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Glycine; Histidine; Hydrogen Peroxide; Leucine; Myoglobin; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
NUTRITIONAL AND REGULATORY ASPECTS OF SERINE METABOLISM IN ESCHERICHIA COLI.
Topics: Adenine Nucleotides; Amino Acids; Carbohydrate Metabolism; Carbon Isotopes; Escherichia coli; Fructose; Glucose; Glycerolphosphate Dehydrogenase; Glycine; Guanine Nucleotides; Isoleucine; Lactates; Leucine; Metabolism; Methionine; Phosphates; Phosphoric Monoester Hydrolases; Research; Serine; Threonine | 1964 |
SOME PROPERTIES OF METHANOBACTERIUM OMELIANSKII FERREDOXIN.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Chemistry Techniques, Analytical; Cystine; Ferredoxins; Glutamates; Glycine; Iron; Lysine; Methanobacterium; Proline; Serine; Spectrophotometry; Sulfides; Threonine; Tyrosine; Valine | 1964 |
LIQUID-LIQUID EXTRACTION IN THE AUTOANALYZER. DETERMINATION OF TAURINE.
Topics: Adrenalectomy; Alanine; Autoanalysis; Automation; Chemistry Techniques, Analytical; Chloroform; Glycine; Liquid-Liquid Extraction; Rats; Research; Serine; Sulfonic Acids; Taurine; Threonine | 1964 |
CLUSTERING OF FUNCTIONALLY RELATED GENES IN SALMONELLA TYPHIMURIUM.
Topics: Arginine; Cysteine; Escherichia coli; Glycine; Guanine; Histidine; Isoleucine; Leucine; Metabolism; Methionine; Molecular Biology; Mutation; Pantothenic Acid; Proline; Purines; Pyrimidines; Research; Salmonella typhimurium; Serine; Threonine; Tryptophan | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
SUPPRESSION OF THE INHIBITORY ACTION OF GUANIDINE ON VIRUS MULTIPLICATION BY SOME AMINO ACIDS.
Topics: Alanine; Albumins; Amino Acids; Animals; Cattle; Enterovirus; Foot-and-Mouth Disease Virus; Guanidine; Guanidines; Kidney; Leucine; Methionine; Pharmacology; Protein Hydrolysates; Research; Serine; Threonine; Valine | 1964 |
A STUDY OF AMINO ACID OXIDASE SPECIFICITY, USING A NEW SENSITIVE ASSAY.
Topics: Amino Acid Oxidoreductases; Biological Assay; Catalysis; D-Amino-Acid Oxidase; Lysine; Research; Serine; Threonine | 1964 |
THREONINE AND SERINE LINKAGES IN MUCOPOLYSACCHARIDES AND GLYCOPROTEINS.
Topics: Alanine; Aminobutyrates; Animals; Cattle; Chemical Phenomena; Chemistry; Glycoproteins; Glycosaminoglycans; Serine; Sharks; Threonine | 1964 |
STUDIES ON THREONINE AND SERINE DEHYDRASE.
Topics: Adrenalectomy; Brain Chemistry; Dietary Proteins; Hormones; Hydrolases; Hypophysectomy; Intestines; Kidney; Liver; Metabolism; Myocardium; Pharmacology; Rats; Research; Serine; Spectrophotometry; Spleen; Threonine | 1964 |
DILUTE ACID HYDROLYSIS OF PAPAIN. KINETIC STUDIES AND PEPTIDES FROM THE CARBOXYMETHYLATED PROTEIN.
Topics: Alanine; Aspartic Acid; Chromatography; Electrophoresis; Glutamates; Glycine; Hydrolysis; Kinetics; Papain; Peptides; Proteins; Research; Serine; Spectrophotometry; Threonine | 1965 |
HYDROGEN EXCHANGE AT CARBON-HYDROGEN SITES DURING ACID OR ALKALINE TREATMENT OF PROTEINS.
Topics: Amino Acids; Aspartic Acid; Carbon; Chemical Phenomena; Chemistry; Chromatography; Cystine; Glycine; Hydrogen; Insulin; Keratins; Muramidase; Proteins; Radiometry; Research; Ribonucleases; Serine; Threonine; Tritium | 1964 |
VARIATIONS IN KERATOSULFATES.
Topics: Animals; Arachnodactyly; Cartilage; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Chemistry Techniques, Analytical; Cornea; Electrophoresis; Hyaluronoglucosaminidase; Intervertebral Disc; Keratan Sulfate; Marfan Syndrome; Peptide Hydrolases; Polysaccharides; Research; Serine; Sharks; Spectrum Analysis; Threonine | 1965 |
GAS CHROMATOGRAPHY OF VOLATILE AMINO ACID DERIVATIVES. I. ALANINE, GLYCINE, VALINE, LEUCINE, ISOLEUCINE, SERINE AND THREONINE.
Topics: Alanine; Arginine; Chromatography; Chromatography, Gas; Equipment and Supplies; Glycine; Isoleucine; Leucine; Research; Serine; Threonine; Valine | 1965 |
INFLUENCE OF PH AND S-RNA CONCENTRATION ON CODING AMBIGUITIES.
Topics: Amino Acids; Escherichia coli; Genetic Code; Hydrogen-Ion Concentration; Isoleucine; Leucine; Magnesium; Phenylalanine; Polynucleotides; Research; RNA; Serine; Threonine; Uracil Nucleotides | 1965 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
THE DISTRIBUTION AND THE BIOLOGICAL SIGNIFICANCE OF L-SERINE ETHANOLAMINE AND L-THREONINE ETHANOLAMINE PHOSPHATES.
Topics: Amino Alcohols; Amphibians; Animals; Biochemical Phenomena; Biochemistry; Brain Chemistry; Chordata; Chromatography; Ethanolamine; Ethanolamines; Fishes; Gonads; Intestinal Mucosa; Intestines; Ion Exchange Resins; Kidney; Liver; Muscles; Myocardium; Phosphates; Physiology, Comparative; Reptiles; Research; Serine; Spinal Cord; Spleen; Threonine | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
STUDIES ON HUMAN ANTIBODIES. 3. AMINO ACID COMPOSITION OF FOUR ANTIBODIES FROM ONE INDIVIDUAL.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Aspartic Acid; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Glycine; Histidine; Immunochemistry; Immunoglobulins; Isoleucine; Leucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1965 |
HORMONAL AND DIETARY CONTROL OF SERINE DEHYDRATASE IN RAT LIVER.
Topics: Adrenalectomy; Amino Acids; Animals; Carbohydrate Metabolism; Dactinomycin; Diabetes Mellitus, Experimental; Diet; Glucokinase; Gluconeogenesis; Growth Hormone; Hydro-Lyases; Hydrocortisone; L-Serine Dehydratase; Liver; Pharmacology; Pyruvates; Rats; Research; Serine; Spectrophotometry; Starvation; Threonine; Toxicology | 1965 |
TRIFLUROACETYLATED AMINO ACID ESTERS: THE STABILITY OF THE DERIVATIVES OF CYSTEINE, HYDROXYPROLINE, SERINE, THREONINE AND TYROSINE.
Topics: Acetates; Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Esters; Hydroxyproline; Research; Serine; Threonine; Tyrosine | 1965 |
DECREASE IN APPETITE AND BIOCHEMICAL CHANGES IN AMINO ACID IMBALANCE IN THE RAT.
Topics: Alanine; Amino Acids; Appetite; Biochemical Phenomena; Biochemistry; Diet; Dietary Proteins; Glutamates; Glutens; Isoleucine; Kwashiorkor; Leucine; Liver; Lysine; Muscles; Proline; Rats; Research; Serine; Threonine; Valine | 1965 |
STUDIES ON GLYCOPROTEINS. XI. THE O-GLYCOSIDIC LINKAGE OF N-ACETYLGALACTOSAMINE TO SERYL AND THREONYL RESIDUES IN OVINE SUBMAXILLARY GLAND GLYCOPROTEIN.
Topics: Acetylgalactosamine; Animals; Biochemical Phenomena; Biochemistry; Chemistry Techniques, Analytical; Chromatography; Electrophoresis; Glycoproteins; Hexosamines; Molecular Weight; Neuraminidase; Peptide Hydrolases; Peptides; Research; Serine; Sheep; Spectrophotometry; Submandibular Gland; Threonine | 1965 |
THE USE OF CHROMATOGRAPHIC PROCEDURES IN THE SYNTHESIS OF 14C-LABELLED PHOSPHODIESTERS.
Topics: Amino Alcohols; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Ion Exchange Resins; Phosphates; Research; Serine; Threonine | 1965 |
THE PERIODATE OXIDATION OF AMINO ACIDS WITH REFERENCE TO STUDIES ON GLYCOPROTEINS.
Topics: Amino Acids; Cysteine; Cystine; Glycoproteins; Histidine; Hydrogen-Ion Concentration; Hydroxyproline; Indoles; Isoleucine; Leucine; Methionine; Oxidation-Reduction; Periodic Acid; Phenylalanine; Proline; Pyrroles; Research; Serine; Threonine; Tryptophan; Tyrosine | 1965 |
ISOLATION AND PROPERTIES OF A HOMOGENEOUS PREPARATION OF CYSTATHIONINE SYNTHETASE-L-SERINE AND L-THREONINE DEHYDRATASE.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography; Cystathionine beta-Synthase; Dietary Proteins; Dogs; Electrophoresis; Hydro-Lyases; Liver; Mice; Molecular Weight; Poultry; Rats; Research; Serine; Sheep; Threonine; Threonine Dehydratase; Ultracentrifugation | 1965 |
THE READ-OUT OF TURNIP YELLOW MOSAIC VIRUS RIBONUCLEIC ACID AS A POLYCISTRONIC MESSENGER IN CELL-FREE SYSTEMS OF ESCHERICHIA COLI.
Topics: Cell-Free System; Escherichia coli; Genetic Code; Kinetics; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Plant Viruses; Proteins; Research; Ribosomes; RNA; RNA, Messenger; RNA, Viral; Serine; Threonine; Tymovirus; Tyrosine | 1965 |
THE SIGNIFICANCE OF NEURAMINIC ACID, SERINE AND THREONINE FOR A GLYCOPROTEIN INHIBITING INFLUENZA VIRUS HAEMAGGLUTINATION.
Topics: Animals; Glycoproteins; Hemagglutination; Hemagglutination Tests; Humans; Neuraminic Acids; Orthomyxoviridae; Research; Serine; Sheep; Sheep, Domestic; Submandibular Gland; Threonine | 1965 |
[Interrelations between glycine, serine and threonine in the hen's egg during embryonal development].
Topics: Animals; Chickens; Eggs; Embryo, Mammalian; Embryo, Nonmammalian; Embryonic Development; Fabaceae; Female; Glycine; Serine; Threonine | 1955 |
p21-activated kinase 2 in neutrophils can be regulated by phosphorylation at multiple sites and by a variety of protein phosphatases.
Topics: Amino Acid Sequence; Animals; Cell Fractionation; Enzyme Activation; Enzyme Inhibitors; Glutathione Transferase; Guinea Pigs; Humans; Mice; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oncogene Protein p21(ras); p21-Activated Kinases; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Threonine | 2003 |
Kinetics of the dimerization of retroviral proteases: the "fireman's grip" and dimerization.
Topics: Algorithms; Animals; Aspartic Acid Endopeptidases; Binding Sites; Dimerization; Enzyme Stability; Fluorescent Dyes; HIV Protease; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Point Mutation; Recombinant Proteins; Retroviridae Proteins; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine | 2003 |
Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway.
Topics: Animals; Aspartic Acid; Binding Sites; Calcium; Capsaicin; Cell Line; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Activation; Humans; Models, Biological; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Point Mutation; Protein Binding; Rats; Receptors, Drug; Serine; Threonine; Transfection | 2003 |
Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Binding Sites; Carrier Proteins; Cell Cycle Proteins; Cell Line; DNA, Complementary; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factors; Genetic Vectors; Humans; Insulin; Mutation; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Structure, Tertiary; Serine; Sirolimus; Threonine; Transfection | 2003 |
Phosphorylation of rat spermatidal protein TP2 by sperm-specific protein kinase A and modulation of its transport into the haploid nucleus.
Topics: Active Transport, Cell Nucleus; Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Blotting, Western; Cell Nucleolus; Cell Nucleus; Cell Separation; Chromosomal Proteins, Non-Histone; Cyclic AMP-Dependent Protein Kinases; Cytosol; DNA-Binding Proteins; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Flow Cytometry; Green Fluorescent Proteins; Haploidy; HeLa Cells; Humans; Luminescent Proteins; Male; Mice; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Protein Isoforms; Protein Structure, Tertiary; Protein Transport; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Serine; Sheep; Spermatozoa; Threonine; Transfection | 2003 |
Dual phosphorylation of phosphoinositide 3-kinase adaptor Grb2-associated binder 2 is responsible for superoxide formation synergistically stimulated by Fc gamma and formyl-methionyl-leucyl-phenylalanine receptors in differentiated THP-1 cells.
Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Cell Differentiation; Cell Line; Cross-Linking Reagents; Drug Synergism; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Formyl Peptide; Receptors, IgG; Serine; Superoxides; Threonine | 2003 |
Ser16-, but not Thr17-phosphorylation of phospholamban influences frequency-dependent force generation in human myocardium.
Topics: Adrenergic beta-Agonists; Adult; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cardiac Output, Low; Cardiomyopathy, Dilated; Case-Control Studies; Female; Humans; Isoenzymes; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Myocardium; Phosphorylation; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Threonine | 2003 |
Amlodipine activates the endothelial nitric oxide synthase by altering phosphorylation on Ser1177 and Thr495.
Topics: Amlodipine; Animals; Aorta; Bradykinin; Bradykinin B2 Receptor Antagonists; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Humans; In Vitro Techniques; Indoles; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred WKY; Serine; Swine; Threonine; Umbilical Veins; Vasodilation | 2003 |
Phosphorylation of the MAPKKK regulator Ste50p in Saccharomyces cerevisiae: a casein kinase I phosphorylation site is required for proper mating function.
Topics: Amino Acid Sequence; Amino Acid Substitution; Casein Kinases; Cell Division; Gene Deletion; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase Kinases; Molecular Sequence Data; Phosphorylation; Promoter Regions, Genetic; Protein Kinases; Protein Precursors; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Sorbitol; Subcellular Fractions; Threonine | 2003 |
Follicle-stimulating hormone receptor polymorphisms in women with normogonadotropic anovulatory infertility.
Topics: Anovulation; Asparagine; Case-Control Studies; Cross-Sectional Studies; Female; Gene Frequency; Genotype; Humans; Infertility, Female; Polymorphism, Genetic; Receptors, FSH; Serine; Threonine | 2003 |
Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; cdc25 Phosphatases; Cell Line; Checkpoint Kinase 1; Cyclin B; Cyclin B1; DNA Replication; Humans; Mitosis; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Kinases; Recombinant Fusion Proteins; Serine; Threonine; Tyrosine 3-Monooxygenase | 2003 |
Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3'-OH kinase-Akt pathway.
Topics: Antibiotics, Antineoplastic; Apoptosis; Biotin; Caspase 9; Caspases; Cell Line; Cell Line, Tumor; Cell Membrane; Chromones; DNA Fragmentation; Down-Regulation; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Hepatocyte Growth Factor; Humans; Immunoblotting; Inositol; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Recombinant Proteins; Serine; Signal Transduction; Threonine; Time Factors | 2004 |
Cloning and characterization of a GABAA receptor gamma2 subunit variant.
Topics: Alternative Splicing; Amino Acid Motifs; Amino Acid Sequence; Cell Line; Cell Membrane; Cloning, Molecular; Exons; Glycine; Humans; Immunohistochemistry; Introns; Microscopy, Fluorescence; Models, Genetic; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Proteins; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Threonine; Tissue Distribution; Transfection; Tyrosine | 2004 |
Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel.
Topics: Acetophenones; Benzopyrans; Calcium; Calmodulin; Catalytic Domain; Cations; Chromatography, Gel; Cobalt; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Electrophysiology; Enzyme Inhibitors; Escherichia coli; HeLa Cells; Histones; Humans; Ion Channels; Ions; Kinetics; Magnesium; Membrane Proteins; Molecular Sequence Data; Myelin Basic Protein; Phosphoamino Acids; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Staurosporine; Threonine; Time Factors; TRPM Cation Channels; Zinc | 2004 |
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5.
Topics: Acetylglucosamine; Active Transport, Cell Nucleus; Alanine; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Nucleus; CREB-Binding Protein; Cytoplasm; Dimerization; DNA-Binding Proteins; Epithelial Cells; Galactosyltransferases; Glycosylation; Growth Substances; Humans; Insecta; Interferons; Lectins; Ligands; Luciferases; Mass Spectrometry; Microscopy, Fluorescence; Milk Proteins; Mutation; Nuclear Proteins; Phosphorylation; Prolactin; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; STAT5 Transcription Factor; Threonine; Trans-Activators; Transcription, Genetic; Transfection; Tumor Suppressor Proteins; Tyrosine | 2004 |
Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells.
Topics: Animals; Insulin-Like Growth Factor II; Mice; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma; Serine; Threonine; Tumor Suppressor Proteins | 2003 |
Deciphering the molecular basis of the broad substrate specificity of alpha-glucosidase from Bacillus sp. SAM1606.
Topics: alpha-Glucosidases; Amino Acid Sequence; Amino Acids; Asparagine; Bacillus; Binding Sites; Catalysis; Evolution, Molecular; Glycine; Isomaltose; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Oligo-1,6-Glucosidase; Phylogeny; Plasmids; Proline; Serine; Substrate Specificity; Threonine; Trehalose | 2003 |
Susceptibility of the hydroxyl groups in serine and threonine to beta-elimination/Michael addition under commonly used moderately high-temperature conditions.
Topics: Hydroxyl Radical; Mass Spectrometry; Organophosphorus Compounds; Peptides; Serine; Temperature; Threonine | 2003 |
HPC2/ELAC2 gene variants associated with incident prostate cancer.
Topics: Age Factors; Alleles; Genetic Predisposition to Disease; Genetic Variation; Genotype; Heterozygote; Homozygote; Humans; Leucine; Logistic Models; Male; Neoplasm Proteins; Prostate; Prostatic Neoplasms; Risk; Serine; Threonine | 2003 |
Expression of phosphorylation of N-methyl-D-aspartate receptor subunits during graded hypoxia in the cerebral cortex of newborn piglets.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Hypoxia; Phosphocreatine; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Serine; Swine; Threonine; Tyrosine | 2004 |
Inositol 1,4,5-trisphosphate receptor (type 1) phosphorylation and modulation by Cdc2.
Topics: Amino Acid Sequence; Animals; Antibodies, Phospho-Specific; Calcium; Calcium Channels; CDC2 Protein Kinase; Cell Cycle; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Jurkat Cells; Phosphorylation; Receptors, Cytoplasmic and Nuclear; Serine; Threonine | 2003 |
Hydrogen bonding alteration of Thr-204 in the complex between pharaonis phoborhodopsin and its transducer protein.
Topics: Alanine; Amino Acid Substitution; Archaeal Proteins; Carotenoids; Deuterium Oxide; Halorhodopsins; Hydrogen Bonding; Natronobacterium; Phenylalanine; Photoreceptors, Microbial; Sensory Rhodopsins; Serine; Spectroscopy, Fourier Transform Infrared; Threonine; Tyrosine | 2003 |
The role of the unfolded state in hairpin stability.
Topics: Biophysical Phenomena; Biophysics; Computer Simulation; Models, Molecular; Mutation; Peptides; Protein Conformation; Protein Folding; Serine; Thermodynamics; Threonine; Time Factors | 2003 |
Poly-L-arginine enhances paracellular permeability via serine/threonine phosphorylation of ZO-1 and tyrosine dephosphorylation of occludin in rabbit nasal epithelium.
Topics: Animals; Arginine; Cell Membrane Permeability; In Vitro Techniques; Male; Membrane Proteins; Nasal Mucosa; Occludin; Peptides; Phosphoproteins; Phosphorylation; Rabbits; Serine; Threonine; Tyrosine; Zonula Occludens-1 Protein | 2003 |
Phosphorylation and mutation of human cardiac troponin I deferentially destabilize the interaction of the functional regions of troponin I with troponin C.
Topics: Amino Acid Sequence; Arginine; Calcium; Cardiomyopathy, Hypertrophic, Familial; Glycine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; Threonine; Troponin C; Troponin I; Tryptophan | 2003 |
Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms.
Topics: 14-3-3 Proteins; Active Transport, Cell Nucleus; Cell Line; Cell Nucleus; Cytoplasm; DNA-Binding Proteins; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Nuclear Localization Signals; Phosphorylation; Protein Sorting Signals; Protein Structure, Tertiary; Serine; Threonine; Transcription Factors; Tyrosine 3-Monooxygenase | 2004 |
Phosphorylation of tau protein to sites found in Alzheimer's disease brain is catalyzed by Ca2+/calmodulin-dependent protein kinase II as demonstrated tandem mass spectrometry.
Topics: Alzheimer Disease; Brain; Brain Chemistry; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catalysis; Gas Chromatography-Mass Spectrometry; Humans; Phosphorylation; Recombinant Proteins; Serine; Spectrometry, Mass, Electrospray Ionization; tau Proteins; Threonine | 2003 |
Acclimation of sperm motility apparatus in seawater-acclimated euryhaline tilapia Oreochromis mossambicus.
Topics: Acclimatization; Analysis of Variance; Aniline Compounds; Animals; Biological Transport; Blotting, Western; Calcium; Electrophoresis, Polyacrylamide Gel; Japan; Male; Microscopy, Confocal; Phosphoproteins; Phosphorylation; Seawater; Serine; Sperm Motility; Threonine; Tilapia; Xanthenes | 2004 |
Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells.
Topics: Anilides; Animals; Apoptosis; bcl-Associated Death Protein; Blotting, Western; Carrier Proteins; Cell Line, Tumor; Cell Survival; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Escherichia coli; Glutathione Transferase; Humans; Ligands; Mice; Models, Genetic; Nitriles; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Androgen; Serine; Signal Transduction; Threonine; Time Factors; Tosyl Compounds; Transcription, Genetic; Transfection | 2004 |
[Effects of site-directed mutagenesis at amino acid residues of GATA-1b different from that of GATA-1a in Xenopus].
Topics: Amino Acids; Animals; DNA-Binding Proteins; Embryo, Nonmammalian; Embryonic Development; Erythroid-Specific DNA-Binding Factors; Erythropoiesis; Histidine; Injections; Mutagenesis, Site-Directed; Mutation; Nervous System; Protein Isoforms; RNA, Messenger; Serine; Threonine; Transcription Factors; Xenopus laevis | 2003 |
Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding.
Topics: 14-3-3 Proteins; Amino Acid Motifs; Cell Cycle Proteins; DNA-Binding Proteins; Forkhead Transcription Factors; Humans; Insulin; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Response Elements; Serine; Threonine; Transcription Factors; Tyrosine 3-Monooxygenase; Ultracentrifugation | 2003 |
An FHA phosphoprotein recognition domain mediates protein EmbR phosphorylation by PknH, a Ser/Thr protein kinase from Mycobacterium tuberculosis.
Topics: Bacterial Proteins; Catalysis; Cytosol; Enzyme Activation; Forkhead Transcription Factors; Mycobacterium tuberculosis; Nuclear Proteins; Pentosyltransferases; Phosphoproteins; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Substrate Specificity; Threonine; Transcription Factors | 2003 |
Multiple phosphorylation events regulate the subcellular localization of GGA1.
Topics: Adaptor Proteins, Vesicular Transport; ADP-Ribosylation Factors; Animals; Biomarkers; Carrier Proteins; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; Golgi Apparatus; HeLa Cells; Humans; Mutation; Phosphorylation; Protein Structure, Tertiary; rab GTP-Binding Proteins; Serine; Subcellular Fractions; Threonine; trans-Golgi Network; Vesicular Transport Proteins | 2004 |
Ser and Thr residues modulate the conformation of pro-kinked transmembrane alpha-helices.
Topics: Amino Acid Sequence; Binding Sites; Computer Simulation; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Receptors, G-Protein-Coupled; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine | 2004 |
Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells.
Topics: Adaptor Proteins, Signal Transducing; Adherens Junctions; Binding Sites; Blotting, Western; Caco-2 Cells; Cadherins; Cell Adhesion; Cell Communication; Cell Differentiation; Cell Line; Cytoskeleton; Discs Large Homolog 1 Protein; Epithelial Cells; Genes, Reporter; Humans; Intestinal Mucosa; Intestines; Luciferases; Membrane Proteins; Microscopy, Fluorescence; Models, Genetic; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Serine; Signal Transduction; src Homology Domains; Subcellular Fractions; Threonine; Transfection; Tyrosine; Zonula Occludens-1 Protein | 2004 |
Inhibition of bile salt-induced apoptosis by cyclic AMP involves serine/threonine phosphorylation of CD95.
Topics: Adenosine; Animals; Apoptosis; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; ErbB Receptors; fas Receptor; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar; Serine; Taurolithocholic Acid; Threonine | 2004 |
Molecular dissection of a critical specificity determinant within the amino acid editing domain of leucyl-tRNA synthetase.
Topics: Amino Acid Substitution; Binding Sites; Computational Biology; DNA Mutational Analysis; Enzyme Stability; Escherichia coli Proteins; Hydrolysis; Leucine-tRNA Ligase; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; RNA Editing; Serine; Substrate Specificity; Surface Properties; Threonine; Valine | 2004 |
Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin receptor EP4 that is essential for agonist-induced beta-arrestin1 recruitment but differs from the apparent principal phosphorylation site.
Topics: Amino Acid Sequence; Arrestins; beta-Arrestins; Cell Line; Endocytosis; Humans; Ligands; Molecular Sequence Data; Mutation; Phosphopeptides; Phosphorylation; Prostaglandins; Protein Structure, Tertiary; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Serine; Signal Transduction; Threonine | 2004 |
Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation.
Topics: Androstadienes; Brain Neoplasms; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Fractionation; Cell Line; Cell Membrane; Cell Nucleus; Cytochromes c; Cytosol; Drug Interactions; Electron Transport Complex IV; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoblotting; Insulin-Like Growth Factor I; Ionophores; Kidney; Mitochondria; Mitochondrial Proton-Translocating ATPases; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphorylation; Porins; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase; Threonine; Time Factors; Voltage-Dependent Anion Channel 1; Wortmannin | 2003 |
Hydrated metal(II) complexes of N-(6-amino-3,4-dihydro-3-methyl-5-nitroso-4-oxopyrimidin-2-yl) derivatives of glycine, glycylglycine, threonine, serine, valine and methionine: a monomeric complex and coordination polymers in one, two and three dimensions
Topics: Amino Acids; Barium; Calcium; Cations, Divalent; Crystallography, X-Ray; Glycine; Glycylglycine; Hydrogen Bonding; Ligands; Methionine; Molecular Conformation; Molecular Structure; Molecular Weight; Nitroso Compounds; Polymers; Pyrimidinones; Serine; Strontium; Threonine; Valine; Water | 2004 |
O-sulfonation of serine and threonine: mass spectrometric detection and characterization of a new posttranslational modification in diverse proteins throughout the eukaryotes.
Topics: Animals; Chromatography, Liquid; Cloning, Molecular; Humans; Lymnaea; Mass Spectrometry; Myosin Light Chains; Peptides; Plasmodium falciparum; Protein Processing, Post-Translational; Protozoan Proteins; Receptor Tyrosine Kinase-like Orphan Receptors; Receptors, Cell Surface; Serine; Threonine | 2004 |
Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity.
Topics: Amino Acid Sequence; Bacterial Proteins; Bacteriocins; Cloning, Molecular; Cysteine; Enzymes; Escherichia coli; Lactococcus lactis; Molecular Sequence Data; Mutation; Protein Precursors; Protein Processing, Post-Translational; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Threonine | 2004 |
Single chain antibodies that recognize the N-glycosylation site.
Topics: Amino Acid Sequence; Animals; Antibodies; Asparagine; Binding Sites; Blotting, Western; Cattle; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Glycosylation; Hexosyltransferases; Humans; Immunoglobulin Variable Region; Kinetics; Membrane Proteins; Oligopeptides; Peptide Library; Serine; Serum Albumin, Bovine; Threonine | 2004 |
Threonine and homoserine in extracts of a methionineless mutant of Neurospora.
Topics: Homoserine; Neurospora; Serine; Threonine | 1951 |
[New research on the specificity of hydrolysis of serine and threonine bonds in proteins].
Topics: Hydrolysis; Sensitivity and Specificity; Serine; Threonine | 1951 |
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water | 2004 |
Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Chromatography, Affinity; Cystathionine beta-Synthase; Glutamine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Nickel; Phenylalanine; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 2004 |
Identification of endogenous phosphorylation sites of bovine medium and low molecular weight neurofilament proteins by tandem mass spectrometry.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Molecular Sequence Data; Molecular Weight; Neurofilament Proteins; Peptide Fragments; Peptide Mapping; Phosphorylation; Protein Structure, Tertiary; Protein Subunits; Sequence Analysis, Protein; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2004 |
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation.
Topics: Active Transport, Cell Nucleus; Binding Sites; Blotting, Western; cdc25 Phosphatases; Cell Cycle Proteins; Cell Line, Tumor; Cell Nucleus; Chromatography, Gel; Cyclin B; Glutathione Transferase; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Microscopy, Confocal; Mitosis; Mutagenesis, Site-Directed; Phosphorylation; Plasmids; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Transport; Recombinant Fusion Proteins; RNA, Messenger; RNA, Small Interfering; Serine; Subcellular Fractions; Threonine; Transfection; Tumor Suppressor Proteins; Tyrosine | 2004 |
Modulation of beta-catenin phosphorylation/degradation by cyclin-dependent kinase 2.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; beta Catenin; CDC2-CDC28 Kinases; Cell Cycle; Cell Line; Cell Line, Tumor; Cyclin-Dependent Kinase 2; Cysteine Endopeptidases; Cytoskeletal Proteins; Cytosol; Down-Regulation; G1 Phase; Glutathione Transferase; HeLa Cells; Humans; Immunoblotting; Molecular Sequence Data; Multienzyme Complexes; Phosphorylation; Plasmids; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Rats; Recombinant Proteins; Serine; Signal Transduction; Subcellular Fractions; Threonine; Time Factors; Trans-Activators; Transfection | 2004 |
The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatin; Gene Deletion; Glutamic Acid; Green Fluorescent Proteins; Histones; Humans; Kinetics; Luminescent Proteins; Lysine; Mice; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Point Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2004 |
Molecular determinants of vanilloid sensitivity in TRPV1.
Topics: Amino Acid Sequence; Animals; Calcium; Capsaicin; Cations; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Ganglia, Spinal; Hot Temperature; Humans; Hydrogen-Ion Concentration; In Situ Hybridization; Inhibitory Concentration 50; Ligands; Methionine; Models, Molecular; Molecular Sequence Data; Mutation; Neurons; Phorbol Esters; Phylogeny; Protein Binding; Protein Structure, Tertiary; Protons; Rabbits; Rats; Receptors, Drug; Sequence Homology, Amino Acid; Serine; Temperature; Threonine; Transfection; Tyrosine | 2004 |
Modulation of insulin effects on phosphorylation of protein kinase B and glycogen synthesis by tumor necrosis factor-alpha in HepG2 cells.
Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Glycogen; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Insulin; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Time Factors; Tumor Necrosis Factor-alpha | 2004 |
Regulation of phospholipase D2 activity by protein kinase C alpha.
Topics: Animals; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Indoles; Maleimides; Phospholipase D; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Serine; Subcellular Fractions; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection | 2004 |
Phosphorylated p40PHOX as a negative regulator of NADPH oxidase.
Topics: Alanine; Animals; Cell Separation; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Enzyme Inhibitors; Humans; Mutagenesis, Site-Directed; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Serine; Sodium Dodecyl Sulfate; Threonine | 2004 |
Protein kinase B/Akt regulates coxsackievirus B3 replication through a mechanism which is not caspase dependent.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Binding Sites; Capsid Proteins; Caspases; Chromones; Cysteine Proteinase Inhibitors; Enterovirus B, Human; Enzyme Inhibitors; HeLa Cells; Humans; MAP Kinase Signaling System; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA, Viral; Serine; Threonine; Ultraviolet Rays; Virus Replication | 2004 |
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.
Topics: Amino Acid Sequence; Animals; Antigens, Polyomavirus Transforming; Cell Line; Cell Transformation, Neoplastic; Genes, myc; Humans; Mice; Mutation; Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-myc; Rats; RNA Stability; Serine; Signal Transduction; Threonine | 2004 |
Beta-catenin is temporally regulated during normal liver development.
Topics: Animals; Animals, Newborn; beta Catenin; Cadherins; Cell Division; Cytoskeletal Proteins; Female; Gene Expression Regulation, Developmental; Immunohistochemistry; Liver; Mice; Mice, Inbred ICR; Phosphorylation; Pregnancy; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Serine; Threonine; Trans-Activators; Wnt Proteins; Zebrafish Proteins | 2004 |
Kinetic modeling confirms the biosynthesis of mucin core 1 (beta-Gal(1-3) alpha-GalNAc-O-Ser/Thr) O-glycan structures are modulated by neighboring glycosylation effects.
Topics: Amino Acid Sequence; Animals; Antigens, Tumor-Associated, Carbohydrate; Carbohydrate Conformation; Carbohydrate Sequence; Glycosylation; Kinetics; Models, Chemical; Molecular Sequence Data; Mucins; N-Acetylgalactosaminyltransferases; Oligosaccharides; Polypeptide N-acetylgalactosaminyltransferase; Polysaccharides; Salivary Proteins and Peptides; Serine; Swine; Threonine | 2004 |
Distinct activation mechanisms of protein kinase B by growth-factor stimulation and heat-shock treatment.
Topics: Animals; COS Cells; DNA Mutational Analysis; Enzyme Activation; Heat-Shock Response; Hot Temperature; Mice; Mutagenesis, Site-Directed; NIH 3T3 Cells; Phosphorylation; Platelet-Derived Growth Factor; Protein Conformation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Serine; Signal Transduction; Threonine; Transfection | 2004 |
IFN-gamma induces gp91phox expression in human monocytes via protein kinase C-dependent phosphorylation of PU.1.
Topics: Active Transport, Cell Nucleus; Cell Nucleus; Cells, Cultured; Enzyme Activation; Gene Expression Regulation; Humans; Interferon-gamma; Isoenzymes; Membrane Glycoproteins; Monocytes; NADPH Oxidase 2; NADPH Oxidases; Okadaic Acid; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Proto-Oncogene Proteins; Serine; Threonine; Trans-Activators | 2004 |
Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation.
Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Nucleus; Cisplatin; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Flavonoids; Humans; Immunoblotting; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; NF-kappa B; Phosphoprotein Phosphatases; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Serine; Signal Transduction; Threonine; Transcription Factor RelA; Transfection | 2004 |
Nuclear import and activity of histone deacetylase in Xenopus oocytes is regulated by phosphorylation.
Topics: Active Transport, Cell Nucleus; alpha Karyopherins; Amino Acid Sequence; Animals; Casein Kinase II; Cell Extracts; Chromatin; Dichlororibofuranosylbenzimidazole; Female; Gene Expression; Histone Deacetylases; Molecular Sequence Data; Nuclear Localization Signals; Oocytes; Phosphorylation; Point Mutation; Progesterone; Protein Structure, Tertiary; Rutin; Serine; Threonine; Xenopus | 2004 |
The crystal structure of the Y66L variant of green fluorescent protein supports a cyclization-oxidation-dehydration mechanism for chromophore maturation.
Topics: Amino Acid Substitution; Animals; Crystallization; Crystallography, X-Ray; Genetic Variation; Green Fluorescent Proteins; Heterocyclic Compounds; Hydrogen Bonding; Imidazoles; Leucine; Luminescent Proteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Protein Precursors; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Tyrosine | 2004 |
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
Topics: Animals; Cell Cycle Proteins; Cells, Cultured; Cyclin E; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Humans; Ligases; Mice; Mice, Knockout; Peptides; Phosphorylation; Proto-Oncogene Proteins c-myc; Recombinant Proteins; RNA Interference; S-Phase Kinase-Associated Proteins; Serine; Stem Cells; Threonine; Transcriptional Activation; Ubiquitin; Ubiquitin-Protein Ligases | 2004 |
Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK.
Topics: Activating Transcription Factor 2; Animals; Cell Line; Cell Nucleus; Collagenases; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; NIH 3T3 Cells; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proteins; Recombinant Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation; Transfection | 2004 |
Thr/Ser-rich domain of Aspergillus glucoamylase is essential for secretion.
Topics: Aspergillus; Fungal Proteins; Gene Expression Regulation; Glucan 1,4-alpha-Glucosidase; HSP70 Heat-Shock Proteins; Maltose; Protein Structure, Tertiary; RNA, Messenger; Sequence Deletion; Serine; Threonine | 2004 |
Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Anisomycin; Anthracenes; Brain; Cell Line; Cell Line, Tumor; COS Cells; Down-Regulation; Enzyme Inhibitors; Estradiol; Flavonoids; Genetic Vectors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Neurons; Oxidoreductases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Retroviridae; RNA, Small Interfering; Serine; tau Proteins; Temperature; Threonine; Time Factors; Tumor Suppressor Proteins; Two-Hybrid System Techniques; Tyrosine; WW Domain-Containing Oxidoreductase | 2004 |
Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis.
Topics: Blotting, Northern; Blotting, Western; Cell Line, Tumor; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Interleukin-7; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta; Up-Regulation | 2004 |
Bacterially expressed recombinant p68 RNA helicase is phosphorylated on serine, threonine, and tyrosine residues.
Topics: Blotting, Western; DEAD-box RNA Helicases; Escherichia coli; Phosphorylation; Protein Kinases; Recombinant Proteins; RNA Helicases; Serine; Threonine; Tyrosine | 2004 |
Regulation of the multifunctional Ca2+/calmodulin-dependent protein kinase II by the PP2C phosphatase PPM1F in fibroblasts.
Topics: Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catalytic Domain; Cell Line; Cloning, Molecular; DNA, Complementary; Fibroblasts; Gene Deletion; Gene Expression Regulation, Enzymologic; Humans; Mice; Mutation; Neurons; NIH 3T3 Cells; Peptides; Phosphoprotein Phosphatases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Phosphatase 2C; Rats; Serine; Threonine; Time Factors; Transfection; Vimentin | 2004 |
Chemical clamping allows for efficient phosphorylation of the RNA carrier protein Npl3.
Topics: Adenosine Diphosphate; Binding Sites; Catalysis; Kinetics; Models, Biological; Models, Chemical; Nuclear Proteins; ortho-Aminobenzoates; Peptides; Phosphoproteins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; RNA; RNA-Binding Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Serine; Spectrometry, Fluorescence; Threonine; Time Factors | 2004 |
Identification of mPer1 phosphorylation sites responsible for the nuclear entry.
Topics: Active Transport, Cell Nucleus; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Cell Cycle Proteins; Cell Nucleus; Cells, Cultured; Circadian Rhythm; COS Cells; Cytoplasm; DNA, Complementary; Fatty Acids, Unsaturated; Glutathione Transferase; Immunoblotting; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Period Circadian Proteins; Phosphorylation; Rats; Recombinant Proteins; Serine; Threonine; Time Factors; Transfection | 2004 |
The Phosphorylation Site Database: A guide to the serine-, threonine-, and/or tyrosine-phosphorylated proteins in prokaryotic organisms.
Topics: Archaea; Bacteria; Databases, Factual; Internet; Phosphoproteins; Prokaryotic Cells; Serine; Threonine; Tyrosine | 2004 |
Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells.
Topics: Adenocarcinoma; Amino Acid Substitution; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; Cytoplasm; Enzyme Inhibitors; Glutamic Acid; Humans; Lung Neoplasms; Phosphorylation; Serine; Threonine; Tissue Distribution; Tumor Suppressor Proteins | 2004 |
Positive correlation between overexpression of phospho-BAD with phosphorylated Akt at serine 473 but not threonine 308 in colorectal carcinoma.
Topics: Age Factors; Aged; Apoptosis; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunohistochemistry; Male; Middle Aged; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Up-Regulation | 2004 |
Promotion of hyperphosphorylation by frontotemporal dementia tau mutations.
Topics: Brain; Chromosomes, Human, Pair 17; Dementia; DNA; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Mutagenesis; Mutation; Neurons; Phenotype; Phosphorylation; Plasmids; Point Mutation; Protein Conformation; Protein Isoforms; Protein Kinases; Recombinant Proteins; Serine; tau Proteins; Threonine; Time Factors | 2004 |
The interaction of protein kinase C isozymes alpha, iota, and theta with the cytoplasmic domain of L-selectin is modulated by phosphorylation of the receptor.
Topics: Amino Acid Sequence; Calcium; CD3 Complex; Cross-Linking Reagents; Cyclic GMP; Cytoplasm; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Glutathione Transferase; Humans; Inflammation; Isoenzymes; Jurkat Cells; L-Selectin; Lymphocytes; Mass Spectrometry; Molecular Sequence Data; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-theta; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine | 2004 |
Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides.
Topics: Animals; Apoptosis Regulatory Proteins; Binding Sites; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Cyclic GMP; Death-Associated Protein Kinases; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Male; Models, Biological; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Nucleotides; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Rabbits; Recombinant Proteins; Serine; Threonine; Time Factors | 2004 |
Caspase-mediated specific cleavage of human histone deacetylase 4.
Topics: Amino Acid Motifs; Animals; Apoptosis; Aspartic Acid; Binding Sites; Biological Transport; Caspase 3; Caspases; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cycloheximide; Cysteine Endopeptidases; Dactinomycin; Doxycycline; Genetic Vectors; Glutamic Acid; HeLa Cells; Histone Deacetylases; Humans; Models, Biological; Multienzyme Complexes; Mutagenesis, Site-Directed; Proline; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Threonine; Time Factors; Ultraviolet Rays | 2004 |
Regulation of FOXO3a by brain-derived neurotrophic factor in differentiated human SH-SY5Y neuroblastoma cells.
Topics: Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Brain-Derived Neurotrophic Factor; Carrier Proteins; Cell Differentiation; Cell Line, Tumor; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Membrane Proteins; Neuroblastoma; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Serine; Signal Transduction; Subcellular Fractions; Thapsigargin; Threonine; Transcription Factors; Tretinoin | 2004 |
Temperature dependence of the thrombin-catalyzed proteolysis of prothrombin.
Topics: Animals; Arginine; Blood Coagulation; Catalysis; Chymotrypsin; Hydrolysis; Kinetics; Peptide Fragments; Protein Binding; Prothrombin; Serine; Temperature; Threonine; Thrombin; Trypsin | 2004 |
Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk.
Topics: Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Caspases; cdc42 GTP-Binding Protein; Cell Line; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4F; Eukaryotic Initiation Factor-4G; Glutathione Transferase; Humans; Hydrogen Peroxide; Insecta; Intracellular Signaling Peptides and Proteins; Kinetics; Mice; Molecular Sequence Data; p21-Activated Kinases; Peptides; Phosphorylation; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rabbits; Serine; Threonine; Time Factors; Trypsin | 2004 |
A freestanding proofreading domain is required for protein synthesis quality control in Archaea.
Topics: Acylation; Amino Acid Sequence; Chimera; Gene Deletion; Gene Expression Regulation, Archaeal; Hydrolysis; Molecular Sequence Data; Protein Biosynthesis; Protein Structure, Tertiary; RNA Editing; RNA, Transfer, Amino Acyl; Sequence Homology, Amino Acid; Serine; Sulfolobus; Threonine; Threonine-tRNA Ligase | 2004 |
O-GlcNAc transferase is in a functional complex with protein phosphatase 1 catalytic subunits.
Topics: Animals; Blotting, Western; Brain; Catalytic Domain; Cell Nucleus; Chromatography; Chromatography, Gel; Chromatography, Liquid; Cytosol; Mass Spectrometry; N-Acetylglucosaminyltransferases; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Phosphatase 1; Protein Structure, Tertiary; Rats; Serine; Signal Transduction; Threonine | 2004 |
MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation.
Topics: Cell Division; Cell Line; Endothelium, Vascular; Enzyme Activation; Gene Silencing; HT29 Cells; Humans; Jurkat Cells; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase Kinase Kinase 11; Mitogen-Activated Protein Kinases; Mitogens; Phosphorylation; Proto-Oncogene Proteins c-raf; RNA Interference; Serine; Threonine; Umbilical Veins | 2004 |
Dynamin GTPase domain mutants that differentially affect GTP binding, GTP hydrolysis, and clathrin-mediated endocytosis.
Topics: Adenoviridae; Alanine; Baculoviridae; Binding Sites; Chromatography, Gel; Clathrin; Dynamins; Endocytosis; GTP Phosphohydrolases; Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Lipids; Models, Chemical; Mutation; Oligonucleotides; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Temperature; Threonine; Time Factors; Transferrin | 2004 |
The fourth transmembrane domain of the Helicobacter pylori Na+/H+ antiporter NhaA faces a water-filled channel required for ion transport.
Topics: Alanine; Amino Acid Sequence; Antiporters; Aspartic Acid; Binding Sites; Cell Membrane; Cysteine; Cytoplasm; DNA; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Helicobacter pylori; Ion Transport; Ions; Kinetics; Leucine; Lithium; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Serine; Sodium-Hydrogen Exchangers; Threonine; Valine; Water | 2004 |
Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Animals; Cell Line; CHO Cells; COS Cells; Cricetinae; Cytoplasm; DNA Mutational Analysis; Dose-Response Relationship, Drug; Endocytosis; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Glutathione Transferase; Humans; Immunoblotting; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; Mutation; Phosphoamino Acids; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Tertiary; Proteins; Rats; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Signal Transduction; Threonine; Time Factors; Transfection | 2004 |
A mechanism-based cross-linker for the identification of kinase-substrate pairs.
Topics: Adenosine; Adenosine Triphosphate; Binding Sites; Cross-Linking Reagents; Cysteine; o-Phthalaldehyde; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Substrate Specificity; Threonine | 2004 |
Phosphorylation of tau at THR212 and SER214 in human neuronal and glial cultures: the role of AKT.
Topics: Apoptosis; Astrocytes; Blotting, Western; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Epitopes; Fetus; Gene Expression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; tau Proteins; Threonine; Up-Regulation | 2004 |
In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
Topics: Amino Acids; Animals; Binding Sites; Biological Transport; Blotting, Western; Carrier Proteins; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glucagon; Hepatocytes; Immunoprecipitation; Insulin; Intracellular Signaling Peptides and Proteins; Male; Okadaic Acid; Phosphoproteins; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Recombinant Proteins; Serine; Sirolimus; Threonine; Time Factors; TOR Serine-Threonine Kinases | 2004 |
Cdc28/Cdk1 regulates spindle pole body duplication through phosphorylation of Spc42 and Mps1.
Topics: Alleles; CDC2 Protein Kinase; CDC28 Protein Kinase, S cerevisiae; Cell Cycle; Centrosome; Cytoskeletal Proteins; Gene Expression Regulation; Green Fluorescent Proteins; Luminescent Proteins; Mass Spectrometry; Mitosis; Models, Biological; Mutation; Phosphoproteins; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Spindle Apparatus; Temperature; Threonine | 2004 |
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Topics: Amino Acid Sequence; Binding Sites; Cell Nucleus; Chromatography, Ion Exchange; Computational Biology; HeLa Cells; Humans; Mass Spectrometry; Molecular Sequence Data; Nuclear Proteins; Phosphoproteins; Phosphorylation; Serine; Threonine; Trypsin | 2004 |
Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes.
Topics: Blotting, Western; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Immunoprecipitation; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Liver; MAP Kinase Kinase 4; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Mutagenesis, Site-Directed; Mutation; Organic Anion Transporters, Sodium-Dependent; Phosphorylation; Plasmids; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Recombinant Fusion Proteins; Serine; Symporters; Threonine; Time Factors; Transfection; Ubiquitin | 2004 |
Autocrine transforming growth factor alpha regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells.
Topics: Autocrine Communication; Binding Sites; Biotinylation; Blotting, Western; Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Genes, Dominant; Humans; Immunoblotting; Indoles; Integrin alpha2; Maleimides; Mitogen-Activated Protein Kinase Kinases; Mutation; Phosphorylation; Plasmids; Protein Kinase C; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Signal Transduction; Sirolimus; Threonine; Time Factors; Transfection; Transforming Growth Factor alpha | 2004 |
Only a portion of the small seatbelt loop in human choriogonadotropin appears capable of contacting the lutropin receptor.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Carbon; Chorionic Gonadotropin; COS Cells; Cross-Linking Reagents; Cysteine; Dimerization; Disulfides; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Humans; Hydrogen-Ion Concentration; Ligands; Luteinizing Hormone; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Tertiary; Radioimmunoassay; Receptors, Thyrotropin; Serine; Signal Transduction; Temperature; Threonine | 2004 |
The study of serine-threonine kinases.
Topics: Blood Platelets; Cell Adhesion Molecules; Humans; Microfilament Proteins; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine | 2004 |
Novel CLCN1 mutations in Taiwanese patients with myotonia congenita.
Topics: Adolescent; Adult; Aspartic Acid; Child; Chloride Channels; DNA Mutational Analysis; Female; Glycine; Humans; Isoleucine; Male; Mutation, Missense; Myotonia Congenita; Phenylalanine; Polymorphism, Genetic; Proline; Serine; Taiwan; Threonine | 2004 |
Cell cycle-dependent phosphorylation of C/EBPbeta mediates oncogenic cooperativity between C/EBPbeta and H-RasV12.
Topics: Amino Acid Sequence; Animals; CCAAT-Enhancer-Binding Protein-beta; CDC2-CDC28 Kinases; Cell Cycle; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Enzyme Inhibitors; Genes, ras; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; NIH 3T3 Cells; Phosphorylation; Proto-Oncogene Proteins c-raf; ras Proteins; Sequence Alignment; Serine; Signal Transduction; Threonine | 2004 |
Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.
Topics: Animals; Binding Sites; Brain; Cell Membrane; Chromatography; Chromatography, High Pressure Liquid; COS Cells; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Green Fluorescent Proteins; HeLa Cells; HL-60 Cells; Humans; Isoelectric Focusing; Lipid Metabolism; Microscopy, Confocal; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptides; Phospholipid Transfer Proteins; Phosphorylation; Protein Conformation; Protein Kinase C; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection; Type C Phospholipases | 2004 |
Two threonine residues and two serine residues in the second and third intracellular loops are both involved in histamine H1 receptor downregulation.
Topics: Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Down-Regulation; Histamine; Humans; Molecular Sequence Data; Mutation; Protein Conformation; Receptors, Histamine H1; Serine; Threonine | 2004 |
Carbohydrate recognition factors of a Talpha (Galbeta1-->3GalNAcalpha1-->Ser/Thr) and Tn (GalNAcalpha1-->Ser/Thr) specific lectin isolated from the seeds of Artocarpus lakoocha.
Topics: Acetylation; Artocarpus; Biotinylation; Galactose; Glycosylation; Plant Lectins; Polysaccharides; Protein Binding; Seeds; Serine; Threonine | 2005 |
Expression and activation of Akt/protein kinase B in sexually immature and mature rat uterus.
Topics: Age Distribution; Animals; Enzyme Activation; Estradiol; Female; Gene Expression Regulation, Developmental; Ovariectomy; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Threonine; Uterus | 2004 |
Dietary glycine needs of broiler chicks.
Topics: Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Glycine; Male; Nutritional Requirements; Regression Analysis; Serine; Threonine; Weight Gain | 2004 |
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine | 2004 |
[KatG Ser3 15Thr mutation as the main reason of isoniazid resistance in Mycobacterium tuberculosis isolated in the Novosibirsk and Kemerovo Regions].
Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; Catalase; Drug Resistance, Bacterial; Humans; Isoniazid; Middle Aged; Mutation; Mycobacterium tuberculosis; Serine; Siberia; Threonine | 2004 |
Structured DNA promotes phosphorylation of p53 by DNA-dependent protein kinase at serine 9 and threonine 18.
Topics: Amino Acid Sequence; DNA; DNA-Activated Protein Kinase; DNA-Binding Proteins; DNA, Single-Stranded; Electrophoresis, Polyacrylamide Gel; Humans; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine; Tumor Suppressor Protein p53 | 2004 |
Expression and purification of His-tagged rat mitochondrial short-chain 3-hydroxyacyl-CoA dehydrogenase wild-type and Ser137 mutant proteins.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Amino Acid Sequence; Animals; Circular Dichroism; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mitochondria; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nickel; Oxygen; Plasmids; Rats; Sequence Homology, Amino Acid; Serine; Threonine | 2004 |
Activation of serine/threonine protein phosphatase-1 is required for ceramide-induced survival of sympathetic neurons.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Survival; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Enzyme Activation; Membrane Potentials; Mitochondria; Nerve Growth Factor; Neurons; Phosphatidic Acids; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Retinoblastoma Protein; Serine; Sympathetic Nervous System; Threonine | 2005 |
Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P.
Topics: Allosteric Regulation; Amino Acid Motifs; Amino Acid Sequence; Bacillus megaterium; Bacterial Proteins; DNA; DNA-Binding Proteins; Histidine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Phosphoprotein Phosphatases; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Repressor Proteins; Serine; Threonine; Transcription Factors | 2004 |
Effect of overexpression and nuclear translocation of constitutively active PKB-alpha on cellular survival and proliferation in HepG2 cells.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Cell Nucleus; Cell Proliferation; Cell Survival; Enzyme Activation; Humans; Insulin; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Transcription Factor RelA; Tumor Cells, Cultured | 2004 |
Characterization of the UDP-N-acetylgalactosamine binding domain of bovine polypeptide alphaN-acetylgalactosaminyltransferase T1.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cattle; Gene Expression; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Acetylgalactosaminyltransferases; Point Mutation; Protein Binding; Protein Structure, Tertiary; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine; Uridine Diphosphate N-Acetylgalactosamine | 2004 |
Identification of major ERK-related phosphorylation sites in Gab1.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Enzyme Activation; Gene Expression Regulation; Humans; Insulin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2004 |
Protein kinase C isoforms differentially phosphorylate human choline acetyltransferase regulating its catalytic activity.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Cell Line; Choline O-Acetyltransferase; Enzyme Activation; Humans; In Vitro Techniques; Isoenzymes; Mutagenesis, Site-Directed; Myasthenic Syndromes, Congenital; Neurons; Phosphorylation; Protein Kinase C; Recombinant Proteins; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine | 2004 |
Serine and threonine desaminaes of Escherichia coli; activators for a cell-free enzyme.
Topics: Bacteria; Enzymes; Escherichia coli; Serine; Threonine | 1949 |
Phosphorylation of calmodulin fragments by protein kinase CK2. Mechanistic aspects and structural consequences.
Topics: Amino Acid Sequence; Animals; Calmodulin; Casein Kinase II; Circular Dichroism; Electrophoresis, Gel, Two-Dimensional; Kinetics; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Polylysine; Protein Binding; Protein Folding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Subunits; Rats; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2004 |
The vaccinia virus B1R kinase induces p53 downregulation by an Mdm2-dependent mechanism.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Down-Regulation; Mice; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Serine; Threonine; Tumor Suppressor Protein p53; Vaccinia virus; Viral Proteins | 2004 |
Isolation and characterization of an Arabidopsis mutant that overaccumulates O-Acetyl-L-Ser.
Topics: Amino Acid Sequence; Arabidopsis; Base Sequence; Chromosome Mapping; Gene Expression Regulation, Plant; Molecular Sequence Data; Mutation; Phylogeny; Plants, Genetically Modified; RNA, Messenger; RNA, Plant; Sequence Homology, Amino Acid; Serine; Sulfur; Threonine | 2004 |
Multiple sequence signals determine the distribution of glycosylphosphatidylinositol proteins between the plasma membrane and cell wall in Saccharomyces cerevisiae.
Topics: Cell Membrane; Cell Wall; Glycosylphosphatidylinositols; Protein Sorting Signals; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine | 2004 |
Phorbol ester treatment of K562 cells regulates the transcriptional activity of AML1c through phosphorylation.
Topics: Aspartic Acid; Binding Sites; Blotting, Western; Cell Differentiation; Core Binding Factor Alpha 2 Subunit; DNA-Binding Proteins; Genetic Vectors; Humans; Immunoprecipitation; K562 Cells; Luciferases; Mutation; Phorbol Esters; Phosphorylation; Promoter Regions, Genetic; Protein Structure, Tertiary; Proto-Oncogene Proteins; Serine; Threonine; Time Factors; Transcription Factors; Transcription, Genetic; Transcriptional Activation; U937 Cells | 2004 |
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
Topics: Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Ataxia Telangiectasia Mutated Proteins; Binding Sites; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Nucleus; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Histones; Humans; Hydroxyl Radical; Image Processing, Computer-Assisted; Immunoblotting; Immunoprecipitation; Microscopy, Fluorescence; Oligonucleotides; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Radiation, Ionizing; Reactive Oxygen Species; Serine; Signal Transduction; Threonine; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin | 2004 |
Regulation of corticotropin-releasing hormone receptor type 1alpha signaling: structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated desensitization.
Topics: Adenylyl Cyclases; Animals; Arrestins; beta-Arrestins; Cell Line; Cyclic AMP; Dimerization; Electrophoresis, Polyacrylamide Gel; Endocytosis; Female; Heparin; Humans; Immunoprecipitation; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Muscle Cells; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Polymerase Chain Reaction; Protein Isoforms; Protein Structure, Tertiary; Protein Transport; Rats; Receptors, Corticotropin-Releasing Hormone; Serine; Sheep; Signal Transduction; Threonine; Time Factors; Transfection; Tyrosine | 2005 |
Serine/threonine/tyrosine phosphorylation of the LHX3 LIM-homeodomain transcription factor.
Topics: Amino Acid Sequence; Cell Line; Electrophoresis, Gel, Two-Dimensional; Homeodomain Proteins; Humans; LIM-Homeodomain Proteins; Molecular Sequence Data; Phosphorylation; Sequence Homology, Amino Acid; Serine; Threonine; Transcription Factors; Tyrosine | 2005 |
Migration and retraction of endothelial and epithelial cells require PHI-1, a specific protein-phosphatase-1 inhibitor protein.
Topics: Animals; Brain; Cell Movement; Cells, Cultured; Cytoskeleton; Endothelium, Vascular; Epithelial Cells; Gene Silencing; HeLa Cells; Humans; Immunohistochemistry; Lung; Lymphocytes; Microcirculation; Microscopy, Fluorescence; Phosphoprotein Phosphatases; Phosphorylation; Proteins; Rats; RNA Interference; RNA, Small Interfering; Serine; Threonine; Time Factors; Transfection; Wound Healing | 2004 |
Phosphorylation of phospholamban in ischemia-reperfusion injury: functional role of Thr17 residue.
Topics: Animals; Calcium; Calcium-Binding Proteins; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Phosphorylation; Rats; Rats, Wistar; Serine; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Threonine | 2004 |
Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint.
Topics: Anaphase-Promoting Complex-Cyclosome; Catalysis; Cdc20 Proteins; Cell Cycle Proteins; Genes, cdc; HeLa Cells; Humans; Mitosis; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; RNA Interference; Serine; Spindle Apparatus; Threonine; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligase Complexes | 2004 |
7-hydroxystaurosporine (UCN-01) inhibition of Akt Thr308 but not Ser473 phosphorylation: a basis for decreased insulin-stimulated glucose transport.
Topics: Adipose Tissue; Animals; Antineoplastic Agents; Biological Transport; Blotting, Western; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Glucose Transporter Type 4; Immunoblotting; Insulin; Male; Microsomes; Monosaccharide Transport Proteins; Muscle Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Serine; Staurosporine; Subcellular Fractions; Threonine | 2004 |
Burn injury impairs insulin-stimulated Akt/PKB activation in skeletal muscle.
Topics: Animals; Blood Glucose; Burns; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunoblotting; Insulin; Insulin Resistance; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Skeletal; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Threonine | 2005 |
Regulation of ultraviolet B-induced phosphorylation of histone H3 at serine 10 by Fyn kinase.
Topics: Animals; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Genes, Dominant; Histones; Humans; Isoxazoles; Leflunomide; MAP Kinase Signaling System; Mice; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fyn; RNA, Small Interfering; Serine; Signal Transduction; src-Family Kinases; Threonine; Time Factors; Transfection; Ultraviolet Rays | 2005 |
Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser908 and Thr911.
Topics: Alanine; Alkaline Phosphatase; Amino Acid Substitution; ATP-Binding Cassette Transporters; Cadmium; Electrophoretic Mobility Shift Assay; Fungal Proteins; Gene Deletion; Inactivation, Metabolic; Phosphorylation; Point Mutation; Protein Kinases; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine | 2004 |
A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization.
Topics: Active Transport, Cell Nucleus; Alanine; Amino Acid Sequence; Blotting, Western; Cell Line; Cell Nucleus; Cytoplasm; DNA Mutational Analysis; DNA-Binding Proteins; Exportin 1 Protein; Genes, Reporter; Green Fluorescent Proteins; Humans; Immunoblotting; Interferon Regulatory Factors; Interferons; Karyopherins; Leucine; Luciferases; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Phosphorylation; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Sequence Homology, Amino Acid; Serine; Threonine; Time Factors; Transcription Factors; Transfection | 2005 |
Structural characterization of the Ser324Thr variant of the catalase-peroxidase (KatG) from Burkholderia pseudomallei.
Topics: Bacterial Proteins; Burkholderia pseudomallei; Models, Molecular; Peroxidases; Point Mutation; Protein Structure, Tertiary; Serine; Threonine | 2005 |
Ser95, Asn97, and Thr78 are important for the catalytic function of porcine NADP-dependent isocitrate dehydrogenase.
Topics: Animals; Asparagine; Catalysis; Circular Dichroism; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Kinetics; Models, Molecular; Molecular Weight; Mutation; Recombinant Proteins; Serine; Swine; Threonine | 2005 |
Detection of the site of phosphorylation in a peptide using Raman spectroscopy and partial least squares discriminant analysis.
Topics: Humans; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphorylation; Serine; Spectrum Analysis, Raman; Threonine; Tyrosine | 2005 |
Protein kinase C-mediated phosphorylation of the BGT1 epithelial gamma-aminobutyric acid transporter regulates its association with LIN7 PDZ proteins: a post-translational mechanism regulating transporter surface density.
Topics: Animals; Binding Sites; Carrier Proteins; Clathrin-Coated Vesicles; Dogs; Epithelial Cells; GABA Plasma Membrane Transport Proteins; Membrane Proteins; Membrane Transport Proteins; Mice; Phosphorylation; Protein Kinase C; Serine; Threonine; Vesicular Transport Proteins | 2005 |
Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage.
Topics: Ataxia Telangiectasia Mutated Proteins; Caffeine; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Cyclin B; DNA Damage; DNA-Binding Proteins; Doxorubicin; Enzyme Activation; G2 Phase; Humans; Mitosis; Nocodazole; Phosphorylation; Polo-Like Kinase 1; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Serine; Signal Transduction; Staurosporine; Threonine; Tumor Suppressor Proteins | 2005 |
Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Female; Hippocampus; Histones; Humans; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Postmortem Changes; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Signal Transduction; Threonine | 2005 |
Hypoxia and AMP independently regulate AMP-activated protein kinase activity in heart.
Topics: Acetyl-CoA Carboxylase; Adenosine Monophosphate; AMP-Activated Protein Kinases; Animals; Cytosol; Enzyme Activation; Hypoxia; In Vitro Techniques; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Multienzyme Complexes; Myocardium; Phosphorus Isotopes; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Threonine | 2005 |
Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.
Topics: Animals; Brain Chemistry; Cytosol; Deuterium; Dithiothreitol; Feasibility Studies; Glycosylation; Hydrolysis; Isotope Labeling; Mass Spectrometry; Mice; N-Acetylglucosaminyltransferases; Oxidation-Reduction; Peptide Mapping; Peptides; Phosphorylation; Protein Processing, Post-Translational; Proteins; Proteomics; Serine; Threonine | 2005 |
Caged phosphoproteins.
Topics: Cyclic AMP-Dependent Protein Kinases; Phosphoproteins; RNA, Transfer, Amino Acid-Specific; Serine; Threonine | 2005 |
Role of protein phosphatase 2A in mGluR5-regulated MEK/ERK phosphorylation in neurons.
Topics: Animals; Blotting, Western; Brain; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Immunoprecipitation; MAP Kinase Kinase 1; Marine Toxins; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Okadaic Acid; Oxazoles; Peptides; Phenylacetates; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction; Threonine; Time Factors; Up-Regulation | 2005 |
p38 kinase mediates nitric oxide-induced apoptosis of chondrocytes through the inhibition of protein kinase C zeta by blocking autophosphorylation.
Topics: Animals; Apoptosis; Cartilage, Articular; Cells, Cultured; Chondrocytes; Chromatography, Liquid; Enzyme Activation; Mass Spectrometry; Nitric Oxide; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Rabbits; Recombinant Proteins; Serine; Signal Transduction; Threonine | 2005 |
Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor.
Topics: Alanine; Amino Acid Sequence; Cysteine; DNA Mutational Analysis; Genes, Suppressor; Genetic Testing; Mating Factor; Molecular Sequence Data; Mutagenesis; Peptides; Phenylalanine; Receptors, G-Protein-Coupled; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2005 |
Phosphorylation and glycosylation of bovine lens MP20.
Topics: Amino Acid Sequence; Animals; Cattle; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Glycosylation; Lens, Crystalline; Membrane Proteins; Molecular Sequence Data; Molecular Structure; Peptide Mapping; Phosphorylation; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2005 |
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks.
Topics: Amino Acid Sequence; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Nucleus; DNA Damage; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; HeLa Cells; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Radiation, Ionizing; S Phase; Serine; Threonine | 2005 |
Serine and threonine phospho-specific antibodies to p120-catenin.
Topics: Animals; Catenins; Cell Adhesion Molecules; Chlorocebus aethiops; COS Cells; Delta Catenin; Dogs; Fluorescent Antibody Technique; Humans; Mice; Phosphoproteins; Phosphorylation; Serine; Species Specificity; Threonine | 2004 |
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation.
Topics: Actins; Blood Coagulation Factors; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; Electric Impedance; Endothelium; Endothelium, Vascular; Genes, Dominant; Humans; Immunoprecipitation; Lung; Microscopy, Fluorescence; Models, Biological; Myosin Light Chains; Phosphorylation; Protein Binding; Protein C; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Receptors, Cell Surface; Receptors, Lysosphingolipid; RNA, Small Interfering; Sepsis; Serine; Signal Transduction; Threonine; Thrombin; Time Factors; Transcriptional Activation; Transfection | 2005 |
Uncoupling anaphase-promoting complex/cyclosome activity from spindle assembly checkpoint control by deregulating polo-like kinase 1.
Topics: Anaphase-Promoting Complex-Cyclosome; Cell Cycle Proteins; Cell Line, Tumor; Humans; Mitosis; Mutation; Phosphorylation; Polo-Like Kinase 1; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Serine; Spindle Apparatus; Threonine; Ubiquitin-Protein Ligase Complexes | 2005 |
Rapid microwave-assisted solid-phase glycopeptide synthesis.
Topics: Amino Acid Sequence; Amino Acids; Glycopeptides; Microwaves; Molecular Sequence Data; Serine; Threonine | 2005 |
Proteolysis of macrophage inflammatory protein-1alpha isoforms LD78beta and LD78alpha by neutrophil-derived serine proteases.
Topics: Amino Acid Sequence; Cathepsin G; Cathepsins; Chemokine CCL3; Chemokine CCL4; Chemokines; Chemotaxis; Cytokines; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Inflammation; Macrophage Inflammatory Proteins; Mass Spectrometry; Molecular Sequence Data; Myeloblastin; Neutrophils; Pancreatic Elastase; Peptides; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Time Factors | 2005 |
Glycogen synthase kinase-3beta phosphorylation of MAP1B at Ser1260 and Thr1265 is spatially restricted to growing axons.
Topics: Animals; Axons; Binding Sites; Blotting, Western; Cell Proliferation; Cerebral Cortex; COS Cells; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Epitopes; Gene Expression Regulation, Developmental; Glutathione Transferase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunoblotting; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Mutagenesis, Site-Directed; Mutation; Neurons; Oligonucleotides; Peptides; Phosphorylation; Plasmids; Point Mutation; Protein Binding; Rats; Rats, Wistar; Recombinant Proteins; Serine; Threonine; Time Factors; Transfection; Valine | 2005 |
A serine/threonine-rich motif is one of three nuclear localization signals that determine unidirectional transport of the mineralocorticoid receptor to the nucleus.
Topics: Active Transport, Cell Nucleus; Amino Acid Motifs; Amino Acid Sequence; Animals; Biological Transport; Blotting, Western; Cell Nucleus; COS Cells; Cytoplasm; Fluorescence Recovery After Photobleaching; Fluorescent Antibody Technique, Indirect; Glutathione Transferase; Green Fluorescent Proteins; HeLa Cells; Humans; Ligands; Molecular Sequence Data; Nuclear Localization Signals; Nuclear Matrix; Phosphorylation; Plasmids; Protein Structure, Tertiary; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Serine; Steroids; Threonine; Time Factors; Transfection | 2005 |
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells.
Topics: Acetylcysteine; Apoptosis; Apoptosis Regulatory Proteins; Arsenites; Biliverdine; Blotting, Northern; Blotting, Western; Cell Line; Cell Nucleus; Cell Survival; Cytochromes c; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Silencing; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Luciferases; Membrane Glycoproteins; Membrane Proteins; Oligonucleotides; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Phosphorylation; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Protein Binding; Protein Biosynthesis; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Retroviridae; RNA, Messenger; RNA, Small Interfering; Serine; Sodium Compounds; Threonine; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor AP-1; Transfection; Tumor Necrosis Factor-alpha | 2005 |
c-Jun N-terminal kinase (JNK) positively regulates NFATc2 transactivation through phosphorylation within the N-terminal regulatory domain.
Topics: Amino Acid Sequence; Animals; Binding Sites; DNA; DNA-Binding Proteins; Enzyme Activation; Gene Expression; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 1; Mass Spectrometry; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; NFATC Transcription Factors; Nuclear Proteins; Peptide Fragments; Phosphorylation; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Serine; Signal Transduction; Structure-Activity Relationship; Threonine; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection | 2005 |
Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amino Acids; Animals; Carrier Proteins; Cell Cycle Proteins; Cell Line; Chromones; Cricetinae; Eukaryotic Initiation Factor-4E; Humans; Insulin; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Morpholines; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinases; Rats; Ribosomal Protein S6 Kinases; Sequence Alignment; Serine; Signal Transduction; Sirolimus; Threonine; TOR Serine-Threonine Kinases | 2005 |
Follicle-stimulating hormone activates p70 ribosomal protein S6 kinase by protein kinase A-mediated dephosphorylation of Thr 421/Ser 424 in primary Sertoli cells.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Follicle Stimulating Hormone; Male; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinases; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Sertoli Cells; Sirolimus; Threonine; TOR Serine-Threonine Kinases | 2005 |
Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor.
Topics: Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; Cell Cycle Proteins; Cell Line; Cell Nucleolus; Cell Proliferation; Checkpoint Kinase 1; Humans; NF-kappa B; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; RNA, Small Interfering; Serine; Threonine; Transcription Factor RelA; Transcriptional Activation; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53 | 2005 |
Role of putative anion-binding sites in cytoplasmic and extracellular channels of Natronomonas pharaonis halorhodopsin.
Topics: Anions; Arginine; Binding Sites; Chloride Channels; Chlorides; Circular Dichroism; Cytoplasm; Extracellular Fluid; Halorhodopsins; Lysine; Mutagenesis, Site-Directed; Natronobacterium; Photolysis; Serine; Spectrophotometry; Threonine; Titrimetry | 2005 |
N-acetylmuramic acid as capping element of alpha-D-fucose-containing S-layer glycoprotein glycans from Geobacillus tepidamans GS5-97T.
Topics: Bacillaceae; Carbohydrate Conformation; Carbohydrate Sequence; Electrophoresis, Polyacrylamide Gel; Fucose; Galactose; Glycoproteins; Glycosylation; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Microscopy, Electron; Molecular Sequence Data; Muramic Acids; Polysaccharides; Pronase; Rhamnose; Sequence Analysis; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine | 2005 |
Membrane depolarization induces the undulating phosphorylation/dephosphorylation of glycogen synthase kinase 3beta, and this dephosphorylation involves protein phosphatases 2A and 2B in SH-SY5Y human neuroblastoma cells.
Topics: Androstadienes; Animals; Calcineurin; Calcium; Cell Line; Cell Line, Tumor; Cell Membrane; Enzyme Inhibitors; Glioblastoma; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Humans; Immunoblotting; Immunoprecipitation; Microscopy, Confocal; Naphthalenes; PC12 Cells; Phosphoprotein Phosphatases; Phosphorylation; Potassium Chloride; Rats; Serine; Threonine; Time Factors; Transfection; Wortmannin | 2005 |
p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211.
Topics: Alanine; Animals; Apoptosis; Cell Line; Cell Line, Tumor; Cell Survival; Dexamethasone; DNA; Enzyme Activation; Flow Cytometry; Glucocorticoids; Humans; Immunohistochemistry; Kinetics; Lymphocytes; MAP Kinase Kinase 3; MAP Kinase Signaling System; Mice; Models, Biological; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Propidium; Proto-Oncogene Proteins c-myc; Receptors, Glucocorticoid; RNA, Messenger; Serine; Signal Transduction; Threonine; Time Factors; Transcriptional Activation; Transfection | 2005 |
PKB/AKT is involved in resumption of meiosis in mouse oocytes.
Topics: 4-Butyrolactone; Animals; CDC2 Protein Kinase; Centrosome; Chromones; Enzyme Activation; Female; In Vitro Techniques; Meiosis; Mice; Morpholines; Nuclear Envelope; Okadaic Acid; Oocytes; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2006 |
Mapping of phosphorylation sites of nuclear corepressor receptor interacting protein 140 by liquid chromatography-tandem mass spectroscopy.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Chromatography, Liquid; Insect Proteins; Mass Spectrometry; Molecular Sequence Data; Nuclear Proteins; Nuclear Receptor Interacting Protein 1; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Structure, Tertiary; Repressor Proteins; Serine; Spectrometry, Mass, Electrospray Ionization; Spodoptera; Threonine; Trypsin | 2005 |
Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation.
Topics: Amino Acid Sequence; Animals; Biotin; Blood Platelets; Blotting, Western; Cell Communication; Cell Line; Cloning, Molecular; COS Cells; Cross-Linking Reagents; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Epidermal Growth Factor; Eptifibatide; Flow Cytometry; Humans; Immunoprecipitation; Mass Spectrometry; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Peptides; Peroxidase; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Tissue Distribution; Transfection; Tyrosine | 2005 |
Hyperphosphorylation of the BARD1 tumor suppressor in mitotic cells.
Topics: Cell Cycle; Cell Division; Cell Line; Cell Separation; Cross-Linking Reagents; Dimerization; DNA; DNA Damage; DNA Mutational Analysis; Dose-Response Relationship, Drug; Flow Cytometry; Genetic Vectors; Genotype; HeLa Cells; Humans; Immunoprecipitation; Macromolecular Substances; Mass Spectrometry; Mitomycin; Mitosis; Mutation; Peptides; Phosphorylation; Plasmids; Polymerase Chain Reaction; Protein Binding; Serine; Threonine; Time Factors; Transfection; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2005 |
Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2.
Topics: Arginine; Bacillus; Crystallization; Crystallography, X-Ray; Glutamic Acid; Hordeum; Hydrogen Bonding; Hydrolysis; Methionine; Mutagenesis, Site-Directed; Peptides; Plant Proteins; Protein Binding; Serine; Serine Proteinase Inhibitors; Solvents; Structure-Activity Relationship; Subtilisins; Threonine | 2005 |
Molybdenum oxides as highly effective dehydrative cyclization catalysts for the synthesis of oxazolines and thiazolines.
Topics: Catalysis; Cyclization; Cysteine; Molybdenum; Oxazoles; Serine; Thiazoles; Threonine | 2005 |
Protein kinase C regulates the phosphorylation and oligomerization of ERM binding phosphoprotein 50.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cell Line; Culture Media, Serum-Free; Humans; Molecular Sequence Data; Mutation; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Rats; Recombinant Fusion Proteins; Serine; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Threonine; Transfection | 2005 |
Functional recovery from desensitization of vanilloid receptor TRPV1 requires resynthesis of phosphatidylinositol 4,5-bisphosphate.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Capsaicin; Cell Line; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Inhibitors; Humans; Membrane Potentials; Mutagenesis; Mutagenesis, Site-Directed; Nerve Growth Factor; Oxygenases; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Potassium Channels, Inwardly Rectifying; Rats; Rats, Mutant Strains; Receptor, trkA; Recovery of Function; Serine; Threonine; TRPV Cation Channels | 2005 |
Identification and functional analysis of in vivo phosphorylation sites of the Arabidopsis BRASSINOSTEROID-INSENSITIVE1 receptor kinase.
Topics: Arabidopsis; Arabidopsis Proteins; Binding Sites; Cell Membrane; Conserved Sequence; Mutation; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Signal Transduction; Threonine | 2005 |
Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase.
Topics: Alleles; Androstadienes; Cell Line; Cell Line, Tumor; Culture Media, Serum-Free; Enzyme Inhibitors; Genetic Vectors; Humans; Immunoblotting; Immunoprecipitation; Insulin; Models, Biological; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinases; Protein Structure, Tertiary; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Messenger; RNA, Small Interfering; Serine; Signal Transduction; Sirolimus; Threonine; Time Factors; TOR Serine-Threonine Kinases; Wortmannin | 2005 |
Adrenaline potentiates insulin-stimulated PKB activation via cAMP and Epac: implications for cross talk between insulin and adrenaline.
Topics: Androstadienes; Animals; Cyclic AMP; Drug Synergism; Epinephrine; Glycogen Phosphorylase; Guanine Nucleotide Exchange Factors; Insulin; Male; Muscle, Skeletal; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Serine; Signal Transduction; Threonine; Wortmannin | 2005 |
Pseudo-phosphorylation of tau at Ser202 and Thr205 affects tau filament formation.
Topics: Arachidonic Acid; Blotting, Western; Dose-Response Relationship, Drug; Microscopy, Electron, Transmission; Mutagenesis, Site-Directed; Neurofibrillary Tangles; Phosphorylation; Protein Processing, Post-Translational; Serine; Spectrometry, Fluorescence; tau Proteins; Threonine | 2005 |
Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestins; Cell Line; COS Cells; Culture Media, Serum-Free; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Dose-Response Relationship, Drug; Dynamins; Endocytosis; Enzyme-Linked Immunosorbent Assay; Genes, Dominant; Humans; Immunoblotting; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Sequence Data; Neurons; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Serotonin, 5-HT4; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Serine; Threonine; Time Factors; Transfection | 2005 |
Structural bioinformatics-based design of selective, irreversible kinase inhibitors.
Topics: Amino Acid Sequence; Animals; Binding Sites; Computational Biology; COS Cells; Cysteine; Cytidine Deaminase; Enzyme Inhibitors; Epidermal Growth Factor; Heterocyclic Compounds, 2-Ring; Histones; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Mutation; Phosphorylation; Protein Structure, Tertiary; Ribosomal Protein S6 Kinases, 90-kDa; Sequence Alignment; Serine; Structure-Activity Relationship; Threonine | 2005 |
Inhibition of nuclear import of LIMK2 in endothelial cells by protein kinase C-dependent phosphorylation at Ser-283.
Topics: Active Transport, Cell Nucleus; Binding Sites; Cell Nucleus; Cells, Cultured; Cyclin D1; Cytoplasm; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Activation; Fatty Acids, Unsaturated; Fluorescence Recovery After Photobleaching; G1 Phase; Humans; Immunoprecipitation; Lim Kinases; Microscopy, Fluorescence; Mutation; Phosphorylation; Pichia; Plasmids; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; Resting Phase, Cell Cycle; S Phase; Serine; Threonine; Time Factors; Transfection; Umbilical Veins | 2005 |
A Ser/Thr cluster within the C-terminal domain of the rat prostaglandin receptor EP3alpha is essential for agonist-induced phosphorylation, desensitization and internalization.
Topics: Animals; Base Sequence; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Isoforms; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Serine; Threonine; Transfection | 2005 |
Structure/function analysis of tristetraprolin (TTP): p38 stress-activated protein kinase and lipopolysaccharide stimulation do not alter TTP function.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Arsenites; Cell Line; Cell Line, Tumor; Cytoplasmic Granules; DNA-Binding Proteins; Humans; Immediate-Early Proteins; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polyribosomes; Predictive Value of Tests; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; RNA Stability; Sequence Deletion; Serine; Stress, Physiological; Structure-Activity Relationship; Threonine; Transfection; Tristetraprolin | 2005 |
D-Serine uptake by isolated retinas is consistent with ASCT-mediated transport.
Topics: 4-Chloro-7-nitrobenzofurazan; Alanine; Ambystoma; Amino Acid Transport System ASC; Animals; Biological Transport; Cysteine; Electrophoresis, Capillary; In Vitro Techniques; Retina; Serine; Sodium; Threonine; Time Factors | 2005 |
Varicella-zoster virus IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity.
Topics: Animals; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Line, Tumor; Chlorocebus aethiops; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Cytoplasm; DNA; DNA Mutational Analysis; Down-Regulation; Enzyme Inhibitors; Glutathione Transferase; Herpesvirus 3, Human; Humans; Immediate-Early Proteins; Immunoprecipitation; Mutation; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Kinase Inhibitors; Purines; Roscovitine; Serine; Threonine; Transfection; Vero Cells; Viral Envelope Proteins | 2005 |
Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.
Topics: Animals; Cell Line; Drosophila Proteins; Dyrk Kinases; Insecta; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine | 2005 |
MafA transcription factor is phosphorylated by p38 MAP kinase.
Topics: Amino Acid Sequence; Animals; Cell Differentiation; Chickens; DNA-Binding Proteins; Humans; Lens, Crystalline; Mice; Molecular Sequence Data; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-maf; Quail; Serine; Threonine; Transcription Factors | 2005 |
CDR3 sequence preference of TCRBV8S2+ T cells within the CNS does not reflect single amino acid dependent avidity expansion.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Division; Cell Separation; Central Nervous System; Complementarity Determining Regions; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Guinea Pigs; Haplotypes; Histocompatibility Antigens Class II; Immunization; Myelin Basic Protein; Peptide Fragments; Rats; Rats, Inbred Lew; Receptors, Antigen, T-Cell, alpha-beta; Serine; T-Lymphocytes; Threonine | 2005 |
Identification of Ser153 in ICL2 of the gonadotropin-releasing hormone (GnRH) receptor as a phosphorylation-independent site for inhibition of Gq coupling.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; COS Cells; DNA Primers; Epitopes; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gq-G11; Hydrolysis; Immunoblotting; Inositol Phosphates; Kinetics; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phosphorylation; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Receptors, LHRH; Serine; Threonine; Time Factors; Transfection | 2005 |
Phosphorylation of either Ser16 or Thr30 does not disrupt the structure of the Itch E3 ubiquitin ligase third WW domain.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Biophysics; Magnetic Resonance Spectroscopy; Mice; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Folding; Protein Structure, Tertiary; Proteomics; Serine; Threonine; Ubiquitin-Protein Ligases | 2005 |
Individual and regional variations of phospho-tau species in progressive supranuclear palsy.
Topics: Aged; Amino Acid Sequence; Binding Sites; Blotting, Western; Brain; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Male; Molecular Weight; Neurons; Peptide Fragments; Phosphorylation; Serine; Supranuclear Palsy, Progressive; tau Proteins; Threonine | 2005 |
Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium.
Topics: Aminophenols; Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Caspases; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Culture Media, Serum-Free; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Lithium; Maleimides; MEF2 Transcription Factors; Microscopy, Electron, Transmission; Myogenic Regulatory Factors; Neurons; Neuroprotective Agents; Potassium Deficiency; Rats; Rats, Sprague-Dawley; Serine; Threonine; Time Factors; Transcription Factors | 2005 |
FoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttling.
Topics: Amino Acid Motifs; Cell Line; Cell Nucleus; Cytoplasm; Forkhead Transcription Factors; Humans; Mutation; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Serine; Threonine; Transcription, Genetic | 2005 |
Enhancement of phosphoprotein analysis using a fluorescent affinity tag and mass spectrometry.
Topics: Affinity Labels; Animals; Caseins; Cattle; Chromatography, Affinity; Chromatography, High Pressure Liquid; Fluorescence; Peptide Mapping; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2005 |
Characterization of protein kinase C theta activation loop autophosphorylation and the kinase domain catalytic mechanism.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Binding, Competitive; Catalysis; Catalytic Domain; Enzyme Activation; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Osmolar Concentration; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-theta; Recombinant Proteins; Serine; Substrate Specificity; Threonine | 2005 |
Akt-mediated valosin-containing protein 97 phosphorylation regulates its association with ubiquitinated proteins.
Topics: Adenosine Triphosphatases; Animals; Brain; Cell Cycle Proteins; Hypoxia; Isoelectric Point; Male; PC12 Cells; Phosphatidylinositol 3-Kinases; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Serine; Threonine; Ubiquitin; Valosin Containing Protein | 2005 |
Regulation of peroxisome proliferator-activated receptor alpha by protein kinase C.
Topics: Animals; Cell Line, Tumor; Chlorocebus aethiops; Consensus Sequence; COS Cells; Humans; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Phosphorylation; PPAR alpha; Protein Kinase C; Pyrimidines; Rats; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection | 2005 |
Phosphorylation of AML1/RUNX1 regulates its degradation and nuclear matrix association.
Topics: Animals; Boronic Acids; Bortezomib; Core Binding Factor Alpha 2 Subunit; DNA-Binding Proteins; Immunoprecipitation; Mice; Mice, Knockout; Mutation; Nuclear Matrix; Phosphorylation; Protease Inhibitors; Proto-Oncogene Proteins; Pyrazines; Serine; Threonine; Transcription Factors; Transcription, Genetic; Ubiquitin | 2005 |
Cyclic GMP-dependent protein kinase regulates CCAAT enhancer-binding protein beta functions through inhibition of glycogen synthase kinase-3.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Osteoblasts; Phosphorylation; Protein Binding; Rats; Recombinant Proteins; Serine; Threonine; Time Factors; Transcriptional Activation | 2005 |
Human CDK2 inhibition modifies the dynamics of chromatin-bound minichromosome maintenance complex and replication protein A.
Topics: Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Chromatin; Cyclin-Dependent Kinase 2; DNA; Enzyme Inhibitors; Female; G1 Phase; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunoprecipitation; Male; Minichromosome Maintenance 1 Protein; Mitosis; Nocodazole; Phosphorylation; Protein Binding; Replication Protein A; Retroviridae; RNA, Small Interfering; S Phase; Serine; Threonine; Time Factors; Transfection | 2005 |
Molecular basis of alanine discrimination in editing site.
Topics: Acylation; Alanine; Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Apoenzymes; Bacterial Proteins; Binding Sites; Dimerization; Humans; Models, Molecular; Molecular Sequence Data; Protein Structure, Quaternary; Pyrococcus horikoshii; RNA Editing; RNA, Transfer, Ala; Sequence Alignment; Serine; Substrate Specificity; Threonine; Zinc | 2005 |
Morphine has an antinociceptive effect through activation of the okadaic-acid-sensitive Ser/Thr protein phosphatases PP 2 A and PP5 estimated by tail-pinch test in mice.
Topics: Animals; Area Under Curve; Blotting, Western; Brain; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Narcotics; Nuclear Proteins; Okadaic Acid; Pain; Phosphoprotein Phosphatases; Phosphorylation; Serine; Threonine; Time Factors | 2005 |
Phosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Blotting, Western; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Calcium-Calmodulin-Dependent Protein Kinases; Catalytic Domain; Chlorocebus aethiops; Chromatography, Affinity; Chromatography, Liquid; Cloning, Molecular; COS Cells; Cyclic AMP Response Element-Binding Protein; DNA, Complementary; Drosophila Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutathione Transferase; Intracellular Signaling Peptides and Proteins; Ionomycin; Juvenile Hormones; Mass Spectrometry; Molecular Sequence Data; Nerve Tissue Proteins; Phosphorylation; Polymerase Chain Reaction; Protein Binding; Protein Structure, Tertiary; Proteomics; Rats; Sequence Homology, Amino Acid; Serine; Synapsins; Threonine; Time Factors; Tissue Distribution; Transfection | 2005 |
Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta.
Topics: Amino Acid Sequence; Casein Kinase II; Cell Line; Glutathione Transferase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoblotting; Insulin; Models, Biological; Molecular Sequence Data; Peptide Mapping; Peptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Prions; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RNA Interference; Serine; Threonine; Transfection; Trypsin | 2005 |
Regulation of microfilament organization by Kaposi sarcoma-associated herpes virus-cyclin.CDK6 phosphorylation of caldesmon.
Topics: Actins; Animals; Calmodulin-Binding Proteins; Catalysis; Chromatography, Affinity; Cloning, Molecular; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Viral; HeLa Cells; Herpesvirus 8, Human; Humans; Mass Spectrometry; Mice; Microscopy, Fluorescence; NIH 3T3 Cells; Peptides; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Retinoblastoma Protein; RNA, Small Interfering; Sepharose; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Threonine; Time Factors | 2005 |
Protein tyrosine phosphorylation, hyperactivation and progesterone-induced acrosome reaction are enhanced in IVF media: an effect that is not associated with an increase in protein kinase A activation.
Topics: Acrosome Reaction; Culture Media; Cyclic AMP-Dependent Protein Kinases; Dimethyl Sulfoxide; Enzyme Activation; Fertilization in Vitro; Humans; Male; Phosphorylation; Progesterone; Serine; Sperm Capacitation; Spermatozoa; Threonine; Tyrosine | 2005 |
Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II.
Topics: Atherosclerosis; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catalysis; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Epidermal Growth Factor; ErbB Receptors; Humans; Inflammation; Models, Biological; Mutation; Nitric Oxide; Nitric Oxide Synthase Type III; Peptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Receptor, PAR-1; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; src-Family Kinases; Threonine; Thrombin; Thrombomodulin; Time Factors; Tyrosine; Umbilical Veins | 2005 |
Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A.
Topics: Active Transport, Cell Nucleus; Adenosine Triphosphate; Alkenes; Animals; B-Lymphocytes; Catalysis; Cell Line; Chromatography, Liquid; Cytoplasm; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gene Deletion; Humans; I-kappa B Kinase; Immunoblotting; Immunoprecipitation; Inflammation; Jurkat Cells; Mice; Mice, Inbred C57BL; Mutation; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Polyenes; Protein Phosphatase 2; Pyrones; Sepharose; Serine; Signal Transduction; Spleen; Threonine; Time Factors; Transfection; Tumor Necrosis Factor-alpha | 2005 |
Transient activation of protein phosphatase 2A induced by electroconvulsive shock in the rat frontal cortex.
Topics: Analysis of Variance; Animals; Blotting, Western; Dose-Response Relationship, Radiation; Electroshock; Enzyme Activation; Frontal Lobe; Gene Expression Regulation; Male; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Serine; Threonine; Time Factors | 2005 |
A novel splice variant of human gene NPL, mainly expressed in human liver, kidney and peripheral blood leukocyte.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA, Complementary; Gene Library; Humans; Kidney; Leukocytes; Liver; Mice; Molecular Sequence Data; Open Reading Frames; Oxo-Acid-Lyases; Phosphorylation; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Swine; Threonine; Tissue Distribution | 2005 |
Method development and measurements of endogenous serine/threonine Akt phosphorylation using capillary electrophoresis for systems biology.
Topics: Animals; Electrophoresis, Capillary; Enzyme Activation; PC12 Cells; Peptides; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Serine; Substrate Specificity; Threonine; Ultraviolet Rays | 2005 |
Phosphorylation of the p33 replication protein of Cucumber necrosis tombusvirus adjacent to the RNA binding site affects viral RNA replication.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Blotting, Northern; Molecular Sequence Data; Mutation, Missense; Nicotiana; Phosphorylation; Phosphotransferases; Plant Diseases; Protein Kinase C; Protein Processing, Post-Translational; RNA-Binding Proteins; RNA-Directed DNA Polymerase; RNA, Viral; Serine; Threonine; Tombusvirus; Viral Proteins; Virus Replication | 2005 |
KSHV viral cyclin inactivates p27KIP1 through Ser10 and Thr187 phosphorylation in proliferating primary effusion lymphomas.
Topics: Cell Proliferation; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cytoplasm; Fluorescent Antibody Technique, Indirect; Herpesvirus 8, Human; Humans; Immunoblotting; Immunoprecipitation; Lymphoma, AIDS-Related; Phosphorylation; Protein Transport; Sarcoma, Kaposi; Serine; Subcellular Fractions; Threonine; Tumor Cells, Cultured; Viral Proteins; Virus Replication | 2006 |
Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Asparagine; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Cysteine Synthase; Cytosol; Databases, Protein; Glutamine; Kinetics; Ligands; Methionine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plant Proteins; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Serine; Serine O-Acetyltransferase; Threonine | 2005 |
BAD Ser128 is not phosphorylated by c-Jun NH2-terminal kinase for promoting apoptosis.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Apoptosis; bcl-Associated Death Protein; Erythropoietin; Fibroblasts; HeLa Cells; Humans; Interleukin-3; JNK Mitogen-Activated Protein Kinases; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Serine; Species Specificity; Threonine; Transfection | 2005 |
Nitric oxide regulates prolidase activity by serine/threonine phosphorylation.
Topics: Animals; Blotting, Western; Cyclic GMP; Dipeptidases; DNA, Complementary; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Immunoprecipitation; Inflammation; Matrix Metalloproteinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Pathologic; NIH 3T3 Cells; Nitric Oxide; Nitric Oxide Synthase Type II; Peptides; Phosphorylation; Plasmids; Serine; Signal Transduction; Thiourea; Threonine; Time Factors; Transfection; Wound Healing | 2005 |
Identification of the conserved serine/threonine residues important for gibberellin-sensitivity of Arabidopsis RGL2 protein.
Topics: Arabidopsis; Arabidopsis Proteins; Cells, Cultured; Conserved Sequence; Down-Regulation; Gene Expression Regulation, Plant; Gibberellins; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Mutation; Nicotiana; Phosphoprotein Phosphatases; Plants, Genetically Modified; Proteasome Inhibitors; Serine; Signal Transduction; Threonine; Transcription Factors | 2005 |
Mutational scanning of potassium, sodium and chloride ion channels in malignant migrating partial seizures in infancy.
Topics: Aminopeptidases; Child; Child, Preschool; Chloride Channels; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; DNA Mutational Analysis; Electroencephalography; Endopeptidases; Epilepsies, Partial; Exons; Female; Humans; Infant; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Reverse Transcriptase Polymerase Chain Reaction; Serine; Serine Proteases; Threonine; Tripeptidyl-Peptidase 1 | 2006 |
The Basal phosphorylation sites of endothelial nitric oxide synthase at serine (Ser)1177, Ser116, and threonine (Thr)495 in rat molar epithelial rests of Malassez.
Topics: Animals; Cattle; Goats; Male; Molar; Nitric Oxide Synthase Type III; Periodontal Ligament; Periodontium; Phosphorylation; Rabbits; Rats; Rats, Wistar; Serine; Threonine | 2005 |
Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation.
Topics: Androstadienes; Animals; bcl-Associated Death Protein; Blotting, Western; Cell Count; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gene Silencing; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoprecipitation; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; rap1 GTP-Binding Proteins; RNA Interference; RNA, Double-Stranded; Serine; Signal Transduction; Sulfonamides; Threonine; Thymidine; Time Factors; Up-Regulation; Wortmannin; X-Linked Inhibitor of Apoptosis Protein | 2005 |
Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Marine Toxins; Okadaic Acid; Oxazoles; Phosphatidylinositols; Phosphoprotein Phosphatases; Phosphorylation; Protein Binding; Protein Isoforms; Protein Phosphatase 1; Protein Phosphatase 2; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Pyrans; RNA, Small Interfering; Serine; Signal Transduction; Spiro Compounds; Subcellular Fractions; Threonine; Time Factors | 2005 |
Developmental regulation of protein kinase B activation is isoform specific in skeletal muscle of neonatal pigs.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Animals, Newborn; Blotting, Western; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Immunoprecipitation; Insulin; Muscle, Skeletal; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Swine; Threonine; Time Factors | 2005 |
Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease.
Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Amino Acid Motifs; Amino Acid Sequence; Amyloid beta-Peptides; Anisomycin; Cells, Cultured; Chromatography, Affinity; Humans; Immunoprecipitation; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2006 |
Evaluation of the role of AMP-activated protein kinase and its downstream targets in mammalian hibernation.
Topics: Acetyl-CoA Carboxylase; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Glycogen Synthase; Hibernation; Multienzyme Complexes; Peptide Elongation Factor 2; Phosphorylation; Protein Serine-Threonine Kinases; Sciuridae; Serine; Sterol Esterase; Temperature; Threonine | 2005 |
Regulation of epithelial Na+ channel activity by conserved serine/threonine switches within sorting signals.
Topics: Adaptor Proteins, Vesicular Transport; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Conserved Sequence; Dynamins; Endosomal Sorting Complexes Required for Transport; Epithelial Sodium Channels; Genetic Complementation Test; Humans; In Vitro Techniques; Mice; Multiprotein Complexes; Nedd4 Ubiquitin Protein Ligases; Protein Subunits; Recombinant Proteins; Serine; Signal Transduction; Sodium Channels; Threonine; Transcription Factor AP-2; Ubiquitin-Protein Ligases; Vesicular Transport Proteins | 2005 |
PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.
Topics: Animals; Biopsy; Cell Nucleus; Cells, Cultured; Down-Regulation; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Enzymologic; Heat-Shock Proteins; Humans; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Models, Biological; Muscle, Skeletal; Oxygen; Palmitic Acid; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Promoter Regions, Genetic; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; RNA, Messenger; Serine; Threonine; Transcription Factors; Transcription, Genetic | 2005 |
Substrate specificity and activity regulation of protein kinase MELK.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Binding Sites; Buffers; Calcium; Cell Cycle; Cell Line; Chlorocebus aethiops; COS Cells; Dithiothreitol; Enzyme Activation; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Glutathione; Humans; Ions; Kinetics; Ligands; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Peptides; Phosphorylation; Protein Array Analysis; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; RNA, Messenger; Serine; Stem Cells; Substrate Specificity; Threonine; Tyrosine | 2005 |
Decrease of current responses at human recombinant P2X3 receptors after substitution by Asp of Ser/Thr residues in protein kinase C phosphorylation sites of their ecto-domains.
Topics: Adenosine Triphosphate; Aspartic Acid; Cell Line; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Membrane Potentials; Mutagenesis; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Recombinant Proteins; Serine; Threonine; Transfection; Uridine Triphosphate | 2006 |
Differential contribution of troponin I phosphorylation sites to the endothelin-modulated contractile response.
Topics: Actin Cytoskeleton; Adenoviridae; Alanine; Amiloride; Animals; Binding Sites; Calcium; Cells, Cultured; Cluster Analysis; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Endothelins; Hydrogen-Ion Concentration; Models, Statistical; Muscle Cells; Mutagenesis; Myocardial Contraction; Myocardium; Phosphorylation; Protein Kinase C; Rats; Sarcomeres; Serine; Threonine; Time Factors; Troponin I | 2005 |
LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Female; Leucine; Ligands; Lysine; Membrane Proteins; Molecular Sequence Data; Mutation; Protein Transport; Receptors, Notch; Serine; Signal Transduction; Threonine; Transcription Factors; Ubiquitin-Protein Ligases; Vulva | 2005 |
The mechanism of membrane targeting of human sphingosine kinase 1.
Topics: Amino Acid Sequence; Asparagine; Cell Line; Cell Membrane; DNA Mutational Analysis; Green Fluorescent Proteins; Humans; Kinetics; Lipids; Lysophospholipids; Mass Spectrometry; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Mutation; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pressure; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Sphingosine; Surface Plasmon Resonance; Threonine; Time Factors; Transfection | 2005 |
Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1.
Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Chromatography, Liquid; Glucose; Insulin; Insulin Receptor Substrate Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Trypsin | 2006 |
Regio- and enantioselectivities in epoxide conjugations are modulated by residue 210 in Mu class glutathione transferases.
Topics: Amino Acid Substitution; Catalysis; Epoxy Compounds; Glutathione; Glutathione Transferase; Humans; Kinetics; Models, Molecular; Mutation; Serine; Stereoisomerism; Substrate Specificity; Threonine | 2005 |
Rac1 leads to phosphorylation-dependent increase in stability of the p66shc adaptor protein: role in Rac1-induced oxidative stress.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Chlorocebus aethiops; Enzyme Stability; Mice; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; rac1 GTP-Binding Protein; Rats; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Threonine; Up-Regulation | 2006 |
Paxillin phosphorylation sites mapped by mass spectrometry.
Topics: Animals; Cell Line; Chickens; Chromatography, High Pressure Liquid; Humans; Mice; Paxillin; Phosphorylation; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Transfection; Tyrosine | 2005 |
FAK phosphorylation sites mapped by mass spectrometry.
Topics: Amino Acid Sequence; Animals; Cell Line; Chickens; Focal Adhesion Protein-Tyrosine Kinases; Humans; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Tyrosine | 2005 |
Development of a novel chemical probe for the selective enrichment of phosphorylated serine- and threonine-containing peptides.
Topics: Affinity Labels; Molecular Probes; Peptides; Phosphoproteins; Phosphorylation; Proteomics; Serine; Threonine | 2005 |
GSK-3beta directly phosphorylates and activates MARK2/PAR-1.
Topics: Alzheimer Disease; Binding Sites; Blotting, Western; Brain; Cell Line; Down-Regulation; Enzyme Activation; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hybridomas; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Recombinant Proteins; RNA Interference; RNA, Small Interfering; Serine; Threonine; Transfection | 2005 |
Study of highly constitutively active mutants suggests how cAMP activates cAMP receptor protein.
Topics: beta-Galactosidase; C-Reactive Protein; Cyclic AMP; Cyclic AMP Receptor Protein; Dimerization; DNA; Escherichia coli; Leucine; Methionine; Models, Molecular; Mutation; Plasmids; Promoter Regions, Genetic; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Cyclic AMP; Serine; Threonine; Time Factors; Transcription, Genetic | 2006 |
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation.
Topics: Aged, 80 and over; Alzheimer Disease; Catalytic Domain; Dose-Response Relationship, Drug; Enzyme Activation; Female; Humans; Immunoprecipitation; Iodine Isotopes; Kinetics; Male; Phosphoprotein Phosphatases; Phosphorylation; Postmortem Changes; Serine; tau Proteins; Threonine; Time Factors | 2005 |
A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages.
Topics: Adenosine Triphosphate; Alleles; Animals; Barium; Cell Differentiation; Cell Line; Codon, Terminator; Electrophysiology; Ethidium; Female; Flow Cytometry; Gene Frequency; Green Fluorescent Proteins; Heterozygote; Homozygote; Humans; Interferon-gamma; Lymphocytes; Macrophages; Male; Microscopy, Fluorescence; Monocytes; Mutagenesis, Site-Directed; Mutation; Mycobacterium; Mycobacterium bovis; Oocytes; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Serine; Threonine; Transfection; Xenopus laevis | 2006 |
Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma.
Topics: Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Fibronectins; G2 Phase; Glioblastoma; Glioma; Humans; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Vascular Endothelial Growth Factor A; Vitronectin | 2005 |
Mimicking reverse protein splicing by three-segment tandem peptide ligation.
Topics: Amino Acid Sequence; Cysteine; Inteins; Models, Chemical; Molecular Sequence Data; Peptide Fragments; Protein Engineering; Protein Splicing; Serine; Threonine | 2005 |
Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase.
Topics: Amino Acids; Apoptosis; Cell Cycle Proteins; Cell Line; Cell Nucleus; Checkpoint Kinase 2; DNA Damage; HCT116 Cells; Humans; Immunoblotting; Mutation; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2C; Protein Serine-Threonine Kinases; RNA, Small Interfering; Serine; Threonine; Tumor Suppressor Proteins | 2006 |
Identification of constitutive phosphorylation sites on the Epstein-Barr virus ZEBRA protein.
Topics: Binding Sites; Biochemistry; Cell Line, Tumor; Cell Movement; Cysteine; DNA-Binding Proteins; Escherichia coli; Genetic Vectors; Herpesvirus 4, Human; Humans; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Methionine; Mutagenesis; Peptides; Phosphorylation; Protein Structure, Tertiary; Serine; Threonine; Trans-Activators; Transfection; Trypsin; Tyrosine; Viral Proteins | 2006 |
Regulation of phosphorylation of the GluR1 AMPA receptor by dopamine D2 receptors.
Topics: Adenosine A2 Receptor Antagonists; Amino Acid Sequence; Animals; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Haloperidol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Purines; Quinpirole; Receptors, AMPA; Receptors, Dopamine D2; Serine; Threonine | 2006 |
Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147.
Topics: Alanine; Amino Acid Sequence; Bacteriocins; Chromatography, High Pressure Liquid; Codon; Glycine; Lactococcus lactis; Molecular Sequence Data; Protein Processing, Post-Translational; Serine; Structure-Activity Relationship; Threonine; Valine | 2005 |
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.
Topics: Adenosine Monophosphate; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Enzyme Activation; In Vitro Techniques; Insulin; Male; Multienzyme Complexes; Myocardial Ischemia; Myocardium; Phosphorylation; Protein Serine-Threonine Kinases; Protein Subunits; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Threonine | 2006 |
Conformational changes of yeast plasma membrane H(+)-ATPase during activation by glucose: role of threonine-912 in the carboxy-terminal tail.
Topics: Cell Membrane; Enzyme Activation; Glucose; Models, Molecular; Mutagenesis, Site-Directed; Peptide Mapping; Protein Conformation; Proton-Translocating ATPases; Saccharomyces cerevisiae; Serine; Threonine; Trypsin | 2005 |
Low-dose exposure of intestinal epithelial cells to formaldehyde results in MAP kinase activation and molecular alteration of the focal adhesion protein paxillin.
Topics: Alkaline Phosphatase; Blotting, Western; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Formaldehyde; HT29 Cells; Humans; Immunoprecipitation; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Paxillin; Phosphorylation; Serine; Signal Transduction; Threonine; Tyrosine | 2006 |
Cell adhesion regulates Ser/Thr phosphorylation and proteasomal degradation of HEF1.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Cell Adhesion; Cell Line; Colchicine; Cytochalasin D; Enzyme Inhibitors; Humans; Intermediate Filaments; Marine Toxins; Microtubules; Nocodazole; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Isoforms; Protein Phosphatase 2; Pyrans; Serine; Signal Transduction; Spiro Compounds; Threonine; Tubulin Modulators | 2006 |
Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Dimerization; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Humans; Models, Biological; Models, Molecular; Molecular Sequence Data; Multiprotein Complexes; Peptide Fragments; Phosphorylation; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Sequence Homology, Amino Acid; Serine; Threonine; Transcription Factor DP1; Transcription Factors | 2005 |
P70 S6 kinase mediates tau phosphorylation and synthesis.
Topics: Alzheimer Disease; Cell Line, Tumor; Cell-Free System; Enzyme Activation; Humans; Membrane Proteins; Phosphorylation; Protein Biosynthesis; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Threonine; Zinc | 2006 |
Reduced serine-16 and threonine-17 phospholamban phosphorylation in stunning of conscious dogs: no evidence for any involvement of protein kinase A or protein phosphatases.
Topics: Animals; Blotting, Western; Calcium-Binding Proteins; Cyclic AMP-Dependent Protein Kinases; Dogs; Electrophoresis, Polyacrylamide Gel; Myocardial Stunning; Phosphoprotein Phosphatases; Phosphorylation; Serine; Threonine | 2006 |
Dual inhibition of protein phosphatase-1/2A and calpain rescues nerve growth factor-differentiated PC12 cells from oxygen-glucose deprivation-induced cell death.
Topics: Animals; Blotting, Western; Calpain; Cell Differentiation; CREB-Binding Protein; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glucose; Hypoxia; L-Lactate Dehydrogenase; Nerve Growth Factor; Neural Inhibition; Neurons; Oncogene Protein v-akt; Oxygen; PC12 Cells; Phosphoprotein Phosphatases; Protein Phosphatase 1; Rats; Serine; Spectrin; tau Proteins; Threonine; Time Factors | 2006 |
Expression of Pin1, a peptidyl-prolyl isomerase, in the ovaries of eCG/hCG-treated immature female mice.
Topics: Animals; Blotting, Western; Chorionic Gonadotropin; E2F Transcription Factors; Female; Glycoprotein Hormones, alpha Subunit; Gonadotropins; Mice; Mice, Inbred ICR; Models, Statistical; NIMA-Interacting Peptidylprolyl Isomerase; Ovary; Peptidylprolyl Isomerase; Phosphorylation; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Serine; Signal Transduction; Threonine; Transcription, Genetic | 2006 |
Anomalously phosphorylated tau and Abeta fragments in the CSF correlates with cognitive impairment in MCI subjects.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Blotting, Western; Case-Control Studies; Cognition Disorders; Enzyme-Linked Immunosorbent Assay; Female; Humans; Longitudinal Studies; Male; Neuropsychological Tests; Phosphorylation; Serine; tau Proteins; Threonine | 2006 |
Role of aspartate 143 in Escherichia coli tRNA-guanine transglycosylase: alteration of heterocyclic substrate specificity.
Topics: Amino Acid Substitution; Anticodon; Aspartic Acid; Escherichia coli Proteins; Hypoxanthine; Kinetics; Mutation; Pentosyltransferases; Serine; Substrate Specificity; Threonine; Xanthine | 2006 |
Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils.
Topics: Arachidonic Acid; Aralia; Cell Membrane; Cells, Cultured; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; rac GTP-Binding Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Threonine; Triterpenes; Tyrosine | 2006 |
Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation.
Topics: 14-3-3 Proteins; Alanine; Amino Acid Sequence; Catalysis; Cell Line; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Isoenzymes; MAP Kinase Kinase 6; MAP Kinase Kinase Kinase 3; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Osmotic Pressure; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Serine; Signal Transduction; Threonine | 2006 |
Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium.
Topics: Animals; Caco-2 Cells; Carrier Proteins; Cell Movement; Chlorocebus aethiops; COS Cells; DNA, Complementary; HCT116 Cells; HT29 Cells; Humans; Intestinal Mucosa; Membrane Proteins; Peptides; Phosphorylation; RNA, Messenger; Serine; Signal Transduction; Threonine; Trefoil Factor-2; Trefoil Factor-3; Wound Healing | 2006 |
The APOA4 Thr347->Ser347 polymorphism is not a major risk factor of obesity.
Topics: Adult; Alleles; Apolipoproteins A; Body Mass Index; Exercise; Female; France; Genotype; Humans; Lipids; Lipoproteins; Logistic Models; Male; Middle Aged; Obesity; Polymorphism, Genetic; Prevalence; Risk Factors; Serine; Threonine | 2005 |
Oct-2 DNA binding transcription factor: functional consequences of phosphorylation and glycosylation.
Topics: Amino Acid Sequence; Animals; Dogs; Glycosylation; Humans; Mice; Molecular Sequence Data; Octamer Transcription Factor-2; Phosphorylation; Phylogeny; Protein Binding; Protein Structure, Tertiary; Rats; Sequence Alignment; Serine; Threonine | 2006 |
Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation.
Topics: Algorithms; Alzheimer Disease; Amino Acid Sequence; Chromatography, Liquid; Humans; Immunoblotting; Immunoprecipitation; Lysine; Mass Spectrometry; Molecular Sequence Data; Nerve Degeneration; Neurofibrillary Tangles; Peptides; Phosphorylation; Proteasome Endopeptidase Complex; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Solvents; tau Proteins; Threonine; Trypsin; Ubiquitin | 2006 |
Regulation of p90RSK phosphorylation by SARS-CoV infection in Vero E6 cells.
Topics: Animals; Chlorocebus aethiops; Epidermal Growth Factor; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Signal Transduction; Threonine; Vero Cells | 2006 |
Autophosphorylation of Arabidopsis nucleoside diphosphate kinase 2 occurs only on its active histidine residue.
Topics: Arabidopsis; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Light; Mutation; Nucleoside-Diphosphate Kinase; Phosphates; Phosphorylation; Phytochrome; Protein Binding; Serine; Signal Transduction; Threonine | 2006 |
The autophosphorylated Ser686, Thr688, and Ser689 residues in the intracellular juxtamembrane domain of XA21 are implicated in stability control of rice receptor-like kinase.
Topics: Amino Acid Substitution; Intracellular Space; Microsomes; Mutant Proteins; Oryza; Phosphorylation; Plant Proteins; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Receptors, Cell Surface; Serine; Threonine; Xanthomonas | 2006 |
The G972R variant of the insulin receptor substrate-1 gene impairs insulin signaling and cell differentiation in 3T3L1 adipocytes; treatment with a PPARgamma agonist restores normal cell signaling and differentiation.
Topics: 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Mice; Mitogen-Activated Protein Kinases; Mutation; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pioglitazone; PPAR gamma; Serine; Signal Transduction; Thiazolidinediones; Threonine; Transfection; Tyrosine | 2006 |
A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25.
Topics: 14-3-3 Proteins; Animals; CDC2 Protein Kinase; cdc25 Phosphatases; Cyclin B; Enzyme Activation; Feedback, Physiological; Mitosis; Mutation; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Serine; Threonine; Xenopus | 2006 |
Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase.
Topics: Animals; beta Catenin; Binding Sites; Blotting, Western; Casein Kinase I; Cell Line; Chlorocebus aethiops; COS Cells; CREB-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA; DNA, Complementary; Fluorescent Antibody Technique, Indirect; Genes, Reporter; Glycogen Synthase Kinase 3; Humans; Immunoprecipitation; Luciferases; Models, Genetic; Mutation; Phosphorylation; Protein Binding; Serine; Signal Transduction; Threonine; Transcription, Genetic; Transcriptional Activation | 2006 |
Phosphate group-driven fragmentation of multiply charged phosphopeptide anions. Improved recognition of peptides phosphorylated at serine, threonine, or tyrosine by negative ion electrospray tandem mass spectrometry.
Topics: Amino Acid Sequence; Anions; Phosphates; Phosphopeptides; Phosphorylation; Serine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Threonine; Tyrosine | 2006 |
Analysis of the dynamic Bacillus subtilis Ser/Thr/Tyr phosphoproteome implicated in a wide variety of cellular processes.
Topics: Bacillus subtilis; Bacterial Proteins; Cold Temperature; Culture Media; Electrophoresis, Gel, Two-Dimensional; Hot Temperature; Mass Spectrometry; Osmotic Pressure; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Proteomics; Serine; Threonine; Tyrosine | 2006 |
The vaccinia-related kinases phosphorylate the N' terminus of BAF, regulating its interaction with DNA and its retention in the nucleus.
Topics: Amino Acid Sequence; Animals; Cell Nucleus; Cells, Cultured; DNA; DNA-Binding Proteins; Humans; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Mutation; Nuclear Proteins; Phosphoamino Acids; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteins; Serine; Threonine; Viral Proteins | 2006 |
Quantification of phosphorylation of insulin receptor substrate-1 by HPLC-ESI-MS/MS.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Chromatography, High Pressure Liquid; Humans; Insulin; Insulin Receptor Substrate Proteins; Peptide Fragments; Phosphoproteins; Phosphorylation; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Tumor Necrosis Factor-alpha | 2006 |
Csk mediates G-protein-coupled lysophosphatidic acid receptor-induced inhibition of membrane-bound guanylyl cyclase activity.
Topics: Animals; Atrial Natriuretic Factor; Catalysis; Cell Line; Cell Membrane; CSK Tyrosine-Protein Kinase; Cyclic GMP; Fibroblasts; Gene Expression Regulation; Guanylate Cyclase; Lysophospholipids; Mice; Phosphorylation; Protein-Tyrosine Kinases; Receptors, G-Protein-Coupled; Serine; Signal Transduction; src-Family Kinases; Threonine; Transfection | 2006 |
The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; cdc42 GTP-Binding Protein; Chlorocebus aethiops; COS Cells; Extracellular Signal-Regulated MAP Kinases; Fetus; Gene Expression Regulation, Developmental; GTPase-Activating Proteins; Humans; Mice; Molecular Sequence Data; Phosphoproteins; Phosphorylation; rac1 GTP-Binding Protein; Recombinant Proteins; rhoA GTP-Binding Protein; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 2006 |
[Blood serum and neutrophil amino acid concentrations during hemodialysis].
Topics: Adult; Arginine; Cysteine; Female; Humans; Male; Neutrophils; Renal Dialysis; Renal Insufficiency; Serine; Threonine | 2005 |
Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.
Topics: Alanine; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microdialysis; Phosphorylation; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Serine; Threonine; Time Factors | 2006 |
Modulation of Reelin signaling by Cyclin-dependent kinase 5.
Topics: Animals; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Cyclin-Dependent Kinase 5; Embryo, Mammalian; Extracellular Matrix Proteins; Female; Humans; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Weight; Mutagenesis; Nerve Tissue Proteins; Neurons; Phosphorylation; Reelin Protein; Serine; Serine Endopeptidases; Signal Transduction; Threonine; Transfection | 2007 |
The radiomimetic enediyne C-1027 induces unusual DNA damage responses to double-strand breaks.
Topics: Amino Acids, Cyclic; Aminoglycosides; Antibiotics, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Death; Cells, Cultured; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Damage; DNA-Binding Proteins; Enediynes; Fibroblasts; Humans; Infrared Rays; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Zinostatin | 2006 |
Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution.
Topics: Enzyme Stability; Epoxy Compounds; Evolution, Molecular; Genetic Variation; Glutathione Transferase; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Protein Structure, Tertiary; Serine; Substrate Specificity; Temperature; Threonine | 2006 |
Immobilization of phospholipid-avidin on fused-silica capillaries for chiral separation in open-tubular capillary electrochromatography.
Topics: Adsorption; Avidin; Biotinylation; Chromatography; Electrophoresis, Capillary; Liposomes; Phenylthiohydantoin; Phospholipids; Serine; Silicon Dioxide; Stereoisomerism; Threonine; Tryptophan | 2006 |
Polar networks control oligomeric assembly in membranes.
Topics: Amino Acid Sequence; Fluorescence Resonance Energy Transfer; Kinetics; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Peptides; Protein Folding; Serine; Threonine; Ultracentrifugation | 2006 |
Conserved serine residues in serotonin transporter contribute to high-affinity cocaine binding.
Topics: Amino Acid Sequence; Animals; Bombyx; Cocaine; Conserved Sequence; Drosophila Proteins; HeLa Cells; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Serotonin Plasma Membrane Transport Proteins; Threonine | 2006 |
The ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2.
Topics: Amino Acid Sequence; Cell Line; Cell Line, Tumor; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Gene Expression Regulation; Half-Life; Humans; Hydrolysis; Leupeptins; Ligases; Mutagenesis, Site-Directed; Phosphorylation; Proteins; Serine; Threonine; Transcription Factors; Ubiquitin | 2006 |
Phosphorylation of the neural cell adhesion molecule on serine or threonine residues is induced by adhesion or nerve growth factor.
Topics: Animals; Blotting, Western; Cell Adhesion; Cell Differentiation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunoprecipitation; Nerve Growth Factor; Neural Cell Adhesion Molecules; PC12 Cells; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Serine; Threonine; Time Factors | 2006 |
BID, an interaction partner of protein kinase CK2alpha.
Topics: Amino Acid Sequence; Animals; BH3 Interacting Domain Death Agonist Protein; Casein Kinase II; Caspase 8; Caspases; Catalytic Domain; Immunoprecipitation; Kinetics; Mass Spectrometry; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phosphorylation; Protein Subunits; Recombinant Proteins; Serine; Threonine | 2006 |
Threonine 41 in beta-catenin serves as a key phosphorylation relay residue in beta-catenin degradation.
Topics: Amino Acid Sequence; Animals; beta Catenin; Gene Deletion; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Protein Binding; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Threonine | 2006 |
Regulation of N-formyl peptide receptor signaling and trafficking by individual carboxyl-terminal serine and threonine residues.
Topics: Cell Line; Humans; Mutation; Protein Transport; Receptors, Formyl Peptide; Serine; Signal Transduction; Threonine | 2006 |
Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by arsenic sulphide: involvement of serine/threonine protein phosphatases.
Topics: Arsenicals; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Monocytes; Phosphoprotein Phosphatases; Serine; Structure-Activity Relationship; Sulfides; Threonine | 2006 |
Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.
Topics: Binding Sites; Cells, Cultured; Enzyme Activation; Humans; Hyperkalemia; Hypertension; Intracellular Signaling Peptides and Proteins; Kidney; Minor Histocompatibility Antigens; Mutation; Osmolar Concentration; Phosphorylation; Protein Serine-Threonine Kinases; Sequence Homology, Amino Acid; Serine; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Substrate Specificity; Threonine; WNK Lysine-Deficient Protein Kinase 1 | 2006 |
Conversion of trypsin to a functional threonine protease.
Topics: Amino Acid Substitution; Disulfides; Enzyme Stability; Mutagenesis, Site-Directed; Protein Conformation; Protein Engineering; Serine; Substrate Specificity; Threonine; Trypsin | 2006 |
Structure of the unusual seryl-tRNA synthetase reveals a distinct zinc-dependent mode of substrate recognition.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Archaeal Proteins; Binding Sites; Crystallography, X-Ray; Dimerization; Enzyme Activation; Humans; Methanosarcina barkeri; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Structure, Quaternary; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Serine-tRNA Ligase; Substrate Specificity; Threonine | 2006 |
[Subunits of human holoenzyme of DNA dependent RNA polymerase III phosphorylated in vivo].
Topics: Carcinoma, Squamous Cell; Catalytic Domain; Cell Line, Tumor; Cell Nucleus; Chromatography, DEAE-Cellulose; Holoenzymes; Humans; Immunoblotting; Molecular Weight; Phosphorylation; Placenta; RNA Polymerase III; Serine; Threonine; Tyrosine | 2005 |
Theoretical and experimental investigation of the energetics of cis-trans proline isomerization in peptide models.
Topics: Acetamides; Algorithms; Binding Sites; Catalysis; Hydrogen Bonding; Isomerism; Models, Chemical; Nitrogen; Oxygen; Peptides; Peptidylprolyl Isomerase; Proline; Protons; Pyrrolidines; Serine; Thermodynamics; Threonine | 2006 |
Solid-phase synthesis of 1,3-azole-based peptides and peptidomimetics.
Topics: Amino Acids; Azoles; Combinatorial Chemistry Techniques; Imidazoles; Molecular Mimicry; Oxazoles; Peptides; Serine; Thiazoles; Threonine | 2006 |
Effect of Agkistroden blomhoffi (mamushi) on superoxide generation in human neutrophils.
Topics: Agkistrodon; Animals; Cytochromes c; Electrophoresis, Polyacrylamide Gel; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Protein Transport; rac GTP-Binding Proteins; Serine; Superoxides; Threonine; Tyrosine | 2006 |
Bradykinin mediates phosphorylation of eNOS in odontoblasts.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Down-Regulation; Enzyme Activation; Enzyme Activators; Fluorescent Antibody Technique; Immunohistochemistry; Male; Microscopy, Confocal; Mitogen-Activated Protein Kinase 3; Nitric Oxide Synthase Type III; Odontoblasts; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Threonine; Up-Regulation | 2006 |
Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation.
Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Bacterial Proteins; Catalytic Domain; Cell Line; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; I-kappa B Kinase; MAP Kinase Kinase 6; MAP Kinase Signaling System; NF-kappa B; Phosphorylation; Recombinant Proteins; Serine; Signal Transduction; Threonine; Yersinia | 2006 |
Microbiology. Bacteria seize control by acetylating host proteins.
Topics: Acetylation; Acetyltransferases; Bacterial Proteins; Enzyme Activation; Humans; I-kappa B Kinase; MAP Kinase Kinase 1; MAP Kinase Kinase 6; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Models, Biological; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Serine; Signal Transduction; SUMO-1 Protein; Threonine; Yersinia; Yersinia pestis | 2006 |
Simultaneous detection of tau phospho-epitopes with haptenylated antibodies.
Topics: Alzheimer Disease; Antibodies, Monoclonal; Antibody Specificity; Epitopes; Humans; Immunohistochemistry; Neocortex; Nerve Tissue Proteins; Phosphorylation; Serine; tau Proteins; Threonine | 2006 |
Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Cells, Cultured; Down-Regulation; Enzyme Activation; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Phosphorylation; Protein Kinase C; Rats; Serine; Threonine | 2006 |
The estimation of threonine and serine in proteins.
Topics: Humans; Proteins; Serine; Threonine | 1946 |
Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose.
Topics: 14-3-3 Proteins; Alanine; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Arabidopsis; Arabidopsis Proteins; Binding Sites; Cells, Cultured; Chromatography, Affinity; Deoxyglucose; Glucosyltransferases; Humans; Immunoprecipitation; Multienzyme Complexes; Mutation, Missense; Phenformin; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Threonine | 2006 |
Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes.
Topics: Animals; Animals, Newborn; Calcineurin; Cells, Cultured; Cyclosporine; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Myocytes, Cardiac; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Serine; Threonine | 2006 |
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors".
Topics: Animals; Cells, Cultured; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cytoplasm; Dogs; Enzyme Activation; Humans; Nuclear Localization Signals; Phosphorylation; Receptor Protein-Tyrosine Kinases; Serine; Threonine | 2006 |
Pharmacophore identification: the case of the ser/thr protein phosphatase inhibitors.
Topics: Enzyme Inhibitors; History, 20th Century; History, 21st Century; Humans; Phosphoprotein Phosphatases; Serine; Structure-Activity Relationship; Threonine | 2006 |
Analyses of phosphorylation events in the rubella virus capsid protein: role in early replication events.
Topics: Animals; Capsid; Capsid Proteins; Chlorocebus aethiops; COS Cells; Cricetinae; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; RNA, Viral; Rubella virus; Serine; Threonine; Vero Cells; Virus Assembly; Virus Replication | 2006 |
Increased submaximal insulin-stimulated glucose uptake in mouse skeletal muscle after treadmill exercise.
Topics: AMP-Activated Protein Kinases; Animals; Deoxyglucose; Dose-Response Relationship, Drug; Exercise Test; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Muscle, Skeletal; Phosphorylation; Physical Conditioning, Animal; Protein Serine-Threonine Kinases; Serine; Threonine; Tritium | 2006 |
Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade.
Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cyclic AMP Response Element-Binding Protein; Cytoplasm; Gene Silencing; HeLa Cells; Humans; Mice; Molecular Sequence Data; Multienzyme Complexes; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Serine; Signal Transduction; Staurosporine; Threonine; Trans-Activators; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2006 |
Signalling mechanisms mediated by the phosphoinositide 3-kinase/Akt cascade in synaptic plasticity and memory in the rat.
Topics: Animals; Behavior, Animal; Chromones; Dentate Gyrus; Electrophysiology; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Forkhead Transcription Factors; Long-Term Potentiation; Male; Maze Learning; Memory; Morpholines; Nerve Tissue Proteins; Neuronal Plasticity; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Threonine; TOR Serine-Threonine Kinases | 2006 |
Ser/Thr-rich domains are associated with genetic variation and morphogenesis in Saccharomyces cerevisiae.
Topics: Cluster Analysis; Genetic Variation; Genome, Fungal; Open Reading Frames; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Tandem Repeat Sequences; Threonine | 2006 |
The roles of conserved amino acids on substrate binding and conformational integrity of ClpB N-terminal domain.
Topics: Amino Acid Sequence; Conserved Sequence; Endopeptidase Clp; Escherichia coli Proteins; Heat-Shock Proteins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Structure, Tertiary; Serine; Substrate Specificity; Threonine | 2006 |
Effect of beta-O-glucosylation on L-Ser and L-Thr diamides: a bias toward alpha-helical conformations.
Topics: Carbohydrate Conformation; Diamide; Glucose; Glycopeptides; Protein Conformation; Protein Structure, Secondary; Serine; Thermodynamics; Threonine | 2006 |
Aberrant stabilization of c-Myc protein in some lymphoblastic leukemias.
Topics: Amino Acid Sequence; Blotting, Western; Cell Line; Child; Enzyme Activation; Gene Amplification; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoprecipitation; In Situ Hybridization, Fluorescence; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-myc; Sequence Homology, Amino Acid; Serine; Threonine | 2006 |
A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestin 1; beta-Arrestins; Cells, Cultured; Endocytosis; Extracellular Signal-Regulated MAP Kinases; G-Protein-Coupled Receptor Kinase 2; Humans; Molecular Sequence Data; Mutant Proteins; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Structure, Tertiary; Protein Transport; Receptors, FSH; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine | 2006 |
Phospholipase C epsilon suppresses integrin activation.
Topics: Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Cricetulus; Down-Regulation; Glycine; Integrins; Phosphoinositide Phospholipase C; ras Proteins; Rats; Serine; Signal Transduction; Threonine; Type C Phospholipases; Valine | 2006 |
Control of Listeria superoxide dismutase by phosphorylation.
Topics: Animals; Female; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred BALB C; Phosphorylation; Protein Processing, Post-Translational; Reactive Oxygen Species; Serine; Superoxide Dismutase; Threonine | 2006 |
Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation.
Topics: Animals; Cell Line; Chlorocebus aethiops; Computational Biology; Fluorescent Antibody Technique; Gene Expression; Humans; Immunoprecipitation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neuroblastoma; Phosphorylation; Protein Serine-Threonine Kinases; Sequence Alignment; Serine; tau Proteins; Threonine; Tissue Distribution; Transfection | 2006 |
Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein.
Topics: Amino Acid Sequence; Binding Sites; DNA Mutational Analysis; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Jurkat Cells; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptide Mapping; Phosphorylation; Serine; Threonine; Transfection | 2006 |
Interaction of vanadyl (VO2+) with ligands containing serine, tyrosine, and threonine.
Topics: Crystallography, X-Ray; Ligands; Models, Molecular; Molecular Conformation; Organometallic Compounds; Schiff Bases; Serine; Threonine; Tyrosine; Vanadates | 2006 |
p120 serine and threonine phosphorylation is controlled by multiple ligand-receptor pathways but not cadherin ligation.
Topics: Amino Acid Substitution; Animals; Cadherins; Catenins; Cell Adhesion Molecules; Cell Line, Tumor; Cell Nucleus; Delta Catenin; Dogs; Humans; Ligands; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Receptors, G-Protein-Coupled; RNA, Small Interfering; Serine; Signal Transduction; Threonine | 2006 |
Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance.
Topics: Amino Acid Sequence; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cells, Cultured; Cross-Linking Reagents; DNA Damage; DNA-Binding Proteins; Drug Resistance, Neoplasm; Fanconi Anemia Complementation Group D2 Protein; HeLa Cells; Humans; Mitomycin; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; S Phase; Serine; Threonine; Tumor Suppressor Proteins; Ubiquitin; Ultraviolet Rays | 2006 |
DsdX is the second D-serine transporter in uropathogenic Escherichia coli clinical isolate CFT073.
Topics: Alanine; Amino Acid Transport Systems; Biological Transport; Culture Media; Cycloserine; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Glycine; Kinetics; Membrane Transport Proteins; Models, Biological; Serine; Threonine | 2006 |
The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Calcium; Calmodulin; Catalysis; Electron Transport; Flavin-Adenine Dinucleotide; Humans; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxidation-Reduction; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Threonine | 2006 |
Glycine origin of the methyl substituent on C7'-N of octodiose for the biosynthesis of apramycin.
Topics: Carbohydrate Sequence; Carbon; Carbon Isotopes; Culture Media; Glycine; Molecular Sequence Data; Nebramycin; Nitrogen; Saccharopolyspora; Serine; Threonine | 2006 |
Oxygen alters caveolin-1 and nitric oxide synthase-3 functions in ovine fetal and neonatal lung microvascular endothelial cells.
Topics: Animals; Antibody Specificity; Caveolin 1; Cells, Cultured; Down-Regulation; Endocytosis; Endothelial Cells; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Hypoxia; Lung; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type III; Oxygen; Pertussis Toxin; Phosphorylation; Pregnancy; Protein Kinase C; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Serine; Sheep; Threonine | 2006 |
Hydrogen bonding pathways in human dihydroorotate dehydrogenase.
Topics: Carbon; Cysteine; Dihydroorotate Dehydrogenase; Escherichia coli; Humans; Hydrogen Bonding; Models, Chemical; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Protons; Serine; Solvents; Threonine | 2006 |
Calpain-resistant fragment(s) of alpha-synuclein regulates the synuclein-cleaving activity of 20S proteasome.
Topics: alpha-Synuclein; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Calpain; Electrophoresis, Polyacrylamide Gel; Glutamates; Hydrolysis; Models, Biological; Molecular Sequence Data; Mutation; Proline; Proteasome Endopeptidase Complex; Serine; Substrate Specificity; Swine; Threonine | 2006 |
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
Topics: Action Potentials; Cell Line; Erythromelalgia; Genes, Dominant; Humans; Ion Channel Gating; Membrane Potentials; Models, Chemical; Mutation; NAV1.7 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Serine; Sodium Channels; Threonine; Transfection | 2006 |
Trapping the tetrahedral intermediate in the alkaline phosphatase reaction by substitution of the active site serine with threonine.
Topics: Alkaline Phosphatase; Amino Acid Substitution; Binding Sites; Catalysis; Crystallography, X-Ray; Escherichia coli Proteins; Kinetics; Serine; Thermodynamics; Threonine | 2006 |
Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B.
Topics: Amino Acid Sequence; Calgranulin B; Cell Cycle Proteins; Humans; Molecular Sequence Data; Nuclear Proteins; Peptides; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; S100 Proteins; Serine; Threonine; Tumor Suppressor Protein p53 | 2006 |
SECRET AGENT, an Arabidopsis thaliana O-GlcNAc transferase, modifies the Plum pox virus capsid protein.
Topics: Amino Acid Substitution; Arabidopsis; Arabidopsis Proteins; Base Sequence; Binding Sites; Capsid Proteins; DNA, Viral; Glycosylation; Mutagenesis, Site-Directed; N-Acetylglucosaminyltransferases; Plum Pox Virus; Protein Processing, Post-Translational; Recombinant Proteins; Sequence Deletion; Serine; Threonine | 2006 |
RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.
Topics: Ataxia Telangiectasia Mutated Proteins; Binding Sites; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Chromatin; DNA Damage; DNA-Directed DNA Polymerase; Humans; Hydrogen-Ion Concentration; Mutation; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Replication Protein A; S Phase; Serine; Threonine; Ultraviolet Rays | 2006 |
Predominant alpha2/beta2/gamma3 AMPK activation during exercise in human skeletal muscle.
Topics: Acetyl-CoA Carboxylase; Adult; AMP-Activated Protein Kinases; Exercise; Humans; Male; Multienzyme Complexes; Muscle, Skeletal; Phosphorylation; Physical Endurance; Protein Kinases; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine; Time Factors | 2006 |
Dual alterations in casein kinase I-epsilon and GSK-3beta modulate beta-catenin stability in hyperproliferating colonic epithelia.
Topics: Animals; Axin Protein; beta Catenin; Boronic Acids; Bortezomib; Casein Kinase 1 epsilon; Cell Nucleus; Citrobacter rodentium; Colon; Cyclic AMP Response Element-Binding Protein; Cytoskeleton; DNA; Enterobacteriaceae Infections; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperplasia; Immunoprecipitation; Intestinal Mucosa; Mice; Phosphorylation; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Kinase C; Pyrazines; Repressor Proteins; Serine; TCF Transcription Factors; Threonine; Transcription Factor 7-Like 2 Protein | 2007 |
Phosphorylation of Galpha11 protein contributes to agonist-induced desensitization of 5-HT2A receptor signaling.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurons; Phosphorylation; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT2A; Recombinant Proteins; Serine; Signal Transduction; Threonine; Transfection | 2007 |
Oxidation of L-serine and L-threonine by bis(hydrogen periodato)argentate(III) complex anion: a mechanistic study.
Topics: Anions; Organometallic Compounds; Oxidation-Reduction; Periodic Acid; Serine; Spectrophotometry, Ultraviolet; Threonine | 2007 |
The location and characterisation of the O-linked glycans of the human insulin receptor.
Topics: Acetylgalactosamine; Animals; Cell Line; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Epitopes; Glycopeptides; Glycosylation; Humans; Monosaccharide Transport Proteins; Neural Networks, Computer; Polysaccharides; Protein Conformation; Protein Processing, Post-Translational; Receptor, IGF Type 1; Receptor, Insulin; Recombinant Fusion Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2007 |
Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation.
Topics: Amino Acid Motifs; Amino Acid Sequence; Carrier Proteins; Cell Cycle Proteins; Chromosome Segregation; Epitopes; HeLa Cells; Humans; Kinetochores; Models, Biological; Molecular Sequence Data; Phosphorylation; Polo-Like Kinase 1; Prometaphase; Prophase; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteins; Proto-Oncogene Proteins; Serine; Spindle Apparatus; Threonine | 2006 |
Ecto- and exo-protein kinases in Schistosoma mansoni: regulation of surface phosphorylation by acetylcholine and identification of the alpha subunit of CKII as a major secreted protein kinase.
Topics: Acetylcholine; Animals; Biomphalaria; Casein Kinase II; Caseins; Electrophoresis, Polyacrylamide Gel; Heparin; Mice; Phosphorylation; Phosvitin; Protein Kinase Inhibitors; Protein Kinases; Schistosoma mansoni; Serine; Threonine; Tyrosine | 2005 |
CCAAT/enhancer-binding protein (C/EBP) beta is acetylated at multiple lysines: acetylation of C/EBPbeta at lysine 39 modulates its ability to activate transcription.
Topics: 3T3 Cells; Acetylation; Animals; CCAAT-Binding Factor; CCAAT-Enhancer-Binding Protein-alpha; Cell Cycle Proteins; Growth Hormone; Histone Acetyltransferases; Humans; In Vitro Techniques; Lysine; Mice; Mutagenesis, Site-Directed; p300-CBP Transcription Factors; Promoter Regions, Genetic; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fos; Serine; Threonine; Transcription Factors; Transcriptional Activation | 2007 |
Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2.
Topics: Animals; Biological Transport; Cell Nucleus; Cell Proliferation; Cells, Cultured; Embryo, Mammalian; Endothelial Cells; Fibroblasts; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Osmolar Concentration; Phosphorylation; Protein Isoforms; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Serine; Threonine; TOR Serine-Threonine Kinases; Transcription Factors; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2007 |
Solid-phase synthesis of Stat3 inhibitors incorporating O-carbamoylserine and O-carbamoylthreonine as glutamine mimics.
Topics: Crystallography, X-Ray; Glutamine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Mimicry; Serine; src Homology Domains; STAT3 Transcription Factor; Threonine | 2007 |
Adeno-associated virus 2-mediated gene transfer: role of a cellular serine/threonine protein phosphatase in augmenting transduction efficiency.
Topics: Cell Line; Dependovirus; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Kidney; Nuclear Proteins; Parvoviridae Infections; Phosphoprotein Phosphatases; Phosphorylation; Serine; Staurosporine; Threonine; Transduction, Genetic; Transgenes | 2007 |
Alterations of CREB and DARPP-32 phosphorylation following cocaine and monoaminergic uptake inhibitors.
Topics: Analysis of Variance; Animals; Blotting, Western; Caudate Nucleus; Cocaine; Cyclic AMP Response Element-Binding Protein; Dopamine and cAMP-Regulated Phosphoprotein 32; Dose-Response Relationship, Drug; Drug Administration Schedule; Gene Expression Regulation; Male; Neurotransmitter Uptake Inhibitors; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Threonine | 2007 |
Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer.
Topics: Amino Acid Sequence; Cell Line; Cyclic AMP; Genetic Variation; Hair Color; Humans; Models, Molecular; Molecular Sequence Data; Protein Conformation; Receptor, Melanocortin, Type 1; Recombinant Proteins; Serine; Signal Transduction; Skin Neoplasms; Threonine; Transfection | 2007 |
The functional variant of the CLC-Kb channel T481S is not associated with blood pressure or hypertension in Swedes.
Topics: Adult; Blood Pressure; Chloride Channels; Cohort Studies; Cross-Sectional Studies; Disease Progression; Female; Gene Frequency; Genotype; Humans; Hypertension; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Prevalence; Serine; Sweden; Threonine; Time Factors; White People | 2007 |
Selective enrichment of Ser-/Thr-phosphorylated peptides in the presence of Ser-/Thr-glycosylated peptides.
Topics: Glycopeptides; Molecular Structure; Oligopeptides; Phosphopeptides; Proteomics; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2006 |
In vitro embryonic developmental phosphorylation of the cellular nucleic acid binding protein by cAMP-dependent protein kinase, and its relevance for biochemical activities.
Topics: Amino Acid Sequence; Animals; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Developmental; Molecular Sequence Data; Phosphorylation; Promoter Regions, Genetic; RNA-Binding Proteins; Sequence Homology, Amino Acid; Serine; Threonine; Transcription, Genetic; Transcriptional Activation; Zebrafish; Zebrafish Proteins | 2007 |
Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cells, Cultured; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Fibroblasts; Humans; Kinetics; Phosphorylation; Protein Serine-Threonine Kinases; Radiation, Ionizing; Serine; Threonine; Tumor Suppressor Proteins | 2007 |
Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors.
Topics: Allosteric Regulation; Amino Acid Substitution; Asparagine; Mutagenesis, Site-Directed; N-Methylscopolamine; Proline; Protein Conformation; Receptors, Muscarinic; Serine; Strychnine; Threonine; Valine | 2006 |
Mitogen-activated protein kinase-dependent activation of the Na+/H+ exchanger is mediated through phosphorylation of amino acids Ser770 and Ser771.
Topics: Acidosis; Cell Line; Extracellular Signal-Regulated MAP Kinases; Humans; Immunoprecipitation; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Serine; Sodium-Hydrogen Exchangers; Threonine | 2007 |
Two populations of p27 use differential kinetics to phosphorylate Ser-10 and Thr-187 via phosphatidylinositol 3-Kinase in response to fibroblast growth factor-2 stimulation.
Topics: Animals; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Endothelium, Corneal; Eye; Fibroblast Growth Factor 2; Interphase; Kinetics; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Rabbits; Serine; Threonine | 2007 |
Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; B-Cell CLL-Lymphoma 10 Protein; beta-Transducin Repeat-Containing Proteins; CARD Signaling Adaptor Proteins; Cell Line; Feedback, Physiological; Guanylate Cyclase; Humans; I-kappa B Kinase; Interleukin-2; Lymphocyte Activation; Mutation; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Receptors, Antigen, T-Cell; Serine; T-Lymphocytes; Threonine; Ubiquitin | 2007 |
DNA-PK phosphorylation sites on Oct-1 promote cell survival following DNA damage.
Topics: 3T3 Cells; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Survival; DNA Damage; DNA-Activated Protein Kinase; Dose-Response Relationship, Radiation; Histones; Humans; Mice; Mice, Knockout; Molecular Sequence Data; Octamer Transcription Factor-1; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Serine; Threonine; Transfection | 2007 |
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Binding Sites; Chromatography, Liquid; DNA-Binding Proteins; Genes, Bacterial; Mass Spectrometry; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Repressor Proteins; Serine; Threonine; Tyrosine | 2007 |
A general amphipathic alpha-helical motif for sensing membrane curvature.
Topics: Algorithms; Amino Acid Motifs; Animals; Cell Membrane; Computational Biology; Cytoskeletal Proteins; GTPase-Activating Proteins; Humans; Liposomes; Membrane Proteins; Minor Histocompatibility Antigens; Models, Molecular; Nuclear Pore Complex Proteins; Nuclear Proteins; Protein Folding; Rats; Receptors, Steroid; Saccharomyces cerevisiae Proteins; Serine; Threonine | 2007 |
Sustained activation of extracellular signal-regulated kinase by nerve growth factor regulates c-fos protein stabilization and transactivation in PC12 cells.
Topics: Animals; Blotting, Western; Butadienes; Cell Proliferation; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Luciferases; Matrix Metalloproteinase 3; Mutagenesis; Nerve Growth Factor; Nitriles; PC12 Cells; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Serine; Threonine; Transcription Factor AP-1; Transcriptional Activation; Transfection | 2006 |
Production of dehydroamino acid-containing peptides by Lactococcus lactis.
Topics: Aminobutyrates; Bacterial Proteins; Lactococcus lactis; Mass Spectrometry; Membrane Proteins; Membrane Transport Proteins; Nisin; Peptides; Plasmids; Protein Sorting Signals; Recombinant Fusion Proteins; Serine; Threonine | 2007 |
Novel substrates of Mycobacterium tuberculosis PknH Ser/Thr kinase.
Topics: Bacterial Proteins; Base Sequence; Cloning, Molecular; Computational Biology; Enzyme Activation; Escherichia coli; Molecular Sequence Data; Mutagenesis; Mycobacterium tuberculosis; Plasmids; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Substrate Specificity; Threonine | 2007 |
Protein phosphatases 2A and 1 interact with occludin and negatively regulate the assembly of tight junctions in the CACO-2 cell monolayer.
Topics: Caco-2 Cells; Calcium; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Membrane Proteins; Occludin; Oligonucleotides; Phosphoprotein Phosphatases; Phosphoproteins; Protein Binding; RNA, Small Interfering; Serine; Threonine; Tight Junctions; Zonula Occludens-1 Protein | 2007 |
Phosphorylation-induced conformational changes in short peptides probed by fluorescence resonance energy transfer in the 10A domain.
Topics: Arginine; Fluorescence Resonance Energy Transfer; Models, Chemical; Models, Statistical; Normal Distribution; Peptides; Phosphates; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Serine; Spectrometry, Fluorescence; Stereoisomerism; Threonine; Water | 2007 |
Low energy peptide fragmentations in an ESI-Q-Tof type mass spectrometer.
Topics: Amino Acid Sequence; Dissociative Disorders; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptide Mapping; Sequence Analysis, Protein; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine | 2007 |
Important roles of hydroxylic amino acid residues in the function of Bacillus subtilis adenylosuccinate lyase.
Topics: Adenylosuccinate Lyase; Amino Acid Sequence; Amino Acid Substitution; Bacillus subtilis; Circular Dichroism; Hydroxy Acids; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Serine; Threonine | 2007 |
Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-fluoroorotate: catalytic activity is reflected by the crystal form.
Topics: Amino Acid Substitution; Catalytic Domain; Crystallography, X-Ray; Dihydroorotase; Escherichia coli Proteins; Mutation; Orotic Acid; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine | 2007 |
Neuron-specific phosphorylation of mitogen- and stress-activated protein kinase-1 involved in cerebral hypoxic preconditioning of mice.
Topics: Animals; Blotting, Western; Brain; Disease Models, Animal; Hypoxia, Brain; Immunohistochemistry; Ischemic Preconditioning; Male; Mice; Mice, Inbred BALB C; Neurogranin; Neurons; Phosphorylation; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Threonine; Time Factors | 2007 |
Functional and structural characterization of the first prokaryotic member of the L-amino acid transporter (LAT) family: a model for APC transporters.
Topics: Amino Acid Transport Systems, Neutral; Bacillus subtilis; Biological Transport; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Liposomes; Microscopy, Electron, Transmission; Models, Molecular; Phylogeny; Protein Structure, Tertiary; Serine; Threonine | 2007 |
Site specific phosphorylation of cytochrome c oxidase subunits I, IVi1 and Vb in rabbit hearts subjected to ischemia/reperfusion.
Topics: Amino Acid Sequence; Animals; Chromatography, Liquid; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Glycine; Heart; Molecular Sequence Data; Myocardial Reperfusion Injury; Myocardium; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Rabbits; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine | 2007 |
LRRK2 exon 41 mutations in sporadic Parkinson disease in Europeans.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; DNA Mutational Analysis; Europe; Exons; Female; Histidine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Threonine; Tyrosine | 2007 |
The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors.
Topics: Apoptosis; beta Catenin; Butyrates; Cell Line; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Phosphorylation; Serine; Signal Transduction; Structure-Activity Relationship; Threonine; Wnt Proteins | 2007 |
Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2.
Topics: Animals; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Benzimidazoles; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cells, Cultured; Checkpoint Kinase 1; Checkpoint Kinase 2; Cisplatin; DNA Damage; DNA-Binding Proteins; Doxorubicin; Enzyme Inhibitors; Humans; Immunoprecipitation; Mice; Molecular Structure; Paclitaxel; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Radiation, Ionizing; Recombinant Proteins; Serine; Thiazoles; Threonine; Tumor Suppressor Proteins | 2007 |
Ubiquitin-independent proteasomal degradation of Fra-1 is antagonized by Erk1/2 pathway-mediated phosphorylation of a unique C-terminal destabilizer.
Topics: Amino Acid Sequence; Animals; Cell Cycle; Cell Line; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Neoplasms; Phosphorylation; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fos; Sequence Alignment; Serine; Threonine; Ubiquitin | 2007 |
Identification of C-terminal domain residues involved in protein kinase A-mediated potentiation of kainate receptor subtype 6.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Cell Line; Cyclic AMP-Dependent Protein Kinases; Data Interpretation, Statistical; Electrophysiology; Escherichia coli; GluK2 Kainate Receptor; Glutathione Transferase; Humans; Ion Channels; Molecular Sequence Data; Mutagenesis; Patch-Clamp Techniques; Phosphorylation; Receptors, Kainic Acid; Serine; Structure-Activity Relationship; Threonine; Transfection | 2007 |
Analysis of protein phosphorylation in the regions of consecutive serine/threonine residues by negative ion electrospray collision-induced dissociation. Approach to pinpointing of phosphorylation sites.
Topics: Binding Sites; Molecular Structure; Phosphopeptides; Phosphorylation; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2007 |
Phosphorylation of human inhibitor-1 at Ser67 and/or Thr75 attenuates stimulatory effects of protein kinase A signaling in cardiac myocytes.
Topics: Animals; Binding Sites; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Male; Myocytes, Cardiac; Phosphorylation; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Threonine | 2007 |
Myocilin mutations among primary open angle glaucoma patients of Kanyakumari district, South India.
Topics: Aged; Asian People; Base Sequence; Cytoskeletal Proteins; Eye Proteins; Female; Glaucoma, Open-Angle; Glycoproteins; Humans; India; Leucine; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Proline; Serine; Threonine; Tyrosine | 2007 |
Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis.
Topics: Alanine; Animals; Cyclin-Dependent Kinase 5; Drug Interactions; Endocytosis; Humans; Lipids; Liposomes; Mass Spectrometry; Microscopy, Electron, Scanning; Mutagenesis; Nerve Tissue Proteins; PC12 Cells; Phosphorylation; Protein Kinase Inhibitors; Purines; Rats; Roscovitine; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Transfection | 2007 |
Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
Topics: Amino Acid Sequence; Binding Sites; Cell Cycle Proteins; Cell Line; Cyclin E; Cyclin-Dependent Kinase Inhibitor Proteins; Dimerization; F-Box Proteins; Humans; Models, Biological; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Protein Binding; Protein Structure, Tertiary; S-Phase Kinase-Associated Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Serine; SKP Cullin F-Box Protein Ligases; Structure-Activity Relationship; Substrate Specificity; Threonine; Transfection; Ubiquitin; Ubiquitin-Protein Ligases | 2007 |
The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF.
Topics: Amino Acid Sequence; Animals; Casein Kinase I; Cell Differentiation; Cell Nucleus; Cytoplasm; Embryonic Stem Cells; Fibroblast Growth Factor 2; Forkhead Transcription Factors; HeLa Cells; Humans; Mice; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Neurons; Phosphorylation; Prosencephalon; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Transport; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Transfection; Xenopus laevis; Xenopus Proteins | 2007 |
Interorganelle trafficking of ceramide is regulated by phosphorylation-dependent cooperativity between the PH and START domains of CERT.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Membrane; Ceramides; HeLa Cells; Humans; Membrane Microdomains; Molecular Sequence Data; Mutation; Organelles; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Sequence Alignment; Serine; Threonine | 2007 |
The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage.
Topics: Binding Sites; Dimerization; DNA; DNA Restriction Enzymes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Serine; Substrate Specificity; Threonine | 2007 |
Phosphorylation of human CTP synthetase 1 by protein kinase C: identification of Ser(462) and Thr(455) as major sites of phosphorylation.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Carbon-Nitrogen Ligases; Humans; Isoenzymes; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Saccharomyces cerevisiae; Serine; Threonine | 2007 |
Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3.
Topics: Amino Acid Sequence; Animals; Cell Line; Cytoplasm; Endoplasmic Reticulum; Gammaherpesvirinae; Histocompatibility Antigens Class I; Humans; Lysine; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Protein Structure, Tertiary; Serine; Threonine; Ubiquitin; Ubiquitin-Protein Ligases | 2007 |
Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts.
Topics: Amino Acid Substitution; Ataxia Telangiectasia Mutated Proteins; Catalysis; Cell Cycle Proteins; Cell Extracts; Cell Line, Tumor; DNA Ligase ATP; DNA Ligases; DNA-Activated Protein Kinase; DNA-Binding Proteins; HeLa Cells; Humans; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Suppressor Proteins | 2007 |
Mechanism underlying the iron-dependent nuclear export of the iron-responsive transcription factor Aft1p in Saccharomyces cerevisiae.
Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Cell Nucleus; Iron; Karyopherins; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Trans-Activators; Transcription Factors | 2007 |
Cellular localization and function of DARPP-32 in the rodent retina.
Topics: Animals; Benzazepines; Circadian Rhythm; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Gene Expression Regulation; Immunohistochemistry; Light; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Retina; Rodentia; Serine; Threonine | 2007 |
Expression, generation, and purification of unphosphorylated and phospho-Ser-380/Thr-382/Thr-383 form of recombinant PTEN phosphatase.
Topics: Animals; Cell Line; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Phosphorylation; PTEN Phosphohydrolase; Rats; Recombinant Proteins; Serine; Spodoptera; Threonine | 2007 |
Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation.
Topics: Aurora Kinases; Cell Cycle; Cell Division; Cell Line; Humans; Immunoprecipitation; Microtubules; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Suppressor Proteins | 2007 |
Neutral loss-based phosphopeptide recognition: a collection of caveats.
Topics: Phosphopeptides; Phosphoproteins; Phosphoric Acids; Phosphorylation; Serine; Tandem Mass Spectrometry; Threonine | 2007 |
Physical and functional interaction between mortalin and Mps1 kinase.
Topics: Amino Acid Sequence; Cell Cycle Proteins; Cell Line, Tumor; Centrosome; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Humans; Hydroxyurea; Microscopy, Fluorescence; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; Threonine | 2007 |
Phosphorylation of Irs1 at SER-522 inhibits insulin signaling.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Insulin; Insulin Receptor Substrate Proteins; Phosphoproteins; Phosphorylation; Rabbits; Serine; Signal Transduction; Threonine | 2007 |
Latent membrane protein 1 of Epstein-Barr virus regulates p53 phosphorylation through MAP kinases.
Topics: Cell Line, Tumor; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Mitogen-Activated Protein Kinases; Nasopharyngeal Neoplasms; Phosphorylation; Serine; Threonine; Tumor Suppressor Protein p53; Viral Matrix Proteins | 2007 |
Identification of histidine phosphorylations in proteins using mass spectrometry and affinity-based techniques.
Topics: Bacterial Proteins; Biochemistry; Histidine; Histidine Kinase; Mass Spectrometry; Models, Chemical; Phosphorylation; Protein Kinases; Serine; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine | 2007 |
Synthesis of alkylated sugar amino acids: conformationally restricted L-Xaa-L-Ser/Thr mimics.
Topics: Alkylation; Amino Acids; Dipeptides; Serine; Stereoisomerism; Sugar Acids; Threonine | 2007 |
Serine versus threonine glycosylation: the methyl group causes a drastic alteration on the carbohydrate orientation and on the surrounding water shell.
Topics: Carbohydrates; Glycopeptides; Glycosylation; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Proteins; Serine; Surface Properties; Threonine; Water | 2007 |
Chemical interaction between titanium implant surface and amino acids.
Topics: Amino Acids; Aspartic Acid; Carbon Dioxide; Dental Implants; Electron Probe Microanalysis; Materials Testing; Molecular Structure; Nitrogen; Serine; Surface Properties; Threonine; Titanium | 2007 |
Activation segment exchange: a common mechanism of kinase autophosphorylation?
Topics: Animals; Checkpoint Kinase 2; Crystallography, X-Ray; Dimerization; Humans; Models, Biological; Models, Chemical; Molecular Conformation; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Threonine | 2007 |
The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc.
Topics: Amino Acid Sequence; Antigens, Viral; Cell Line, Tumor; Glycogen Synthase Kinase 3; Herpesvirus 8, Human; Humans; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins c-myc; Sarcoma, Kaposi; Serine; Threonine; Ubiquitin | 2007 |
Insights into the catalytic mechanism of PPM Ser/Thr phosphatases from the atomic resolution structures of a mycobacterial enzyme.
Topics: Bacterial Proteins; Binding Sites; Catalysis; Ligands; Models, Molecular; Mycobacterium smegmatis; Phosphoprotein Phosphatases; Protein Conformation; Recombinant Proteins; Serine; Threonine | 2007 |
On the regioselectivity of thioether formation by lacticin 481 synthetase.
Topics: Bacteriocins; Cysteine; Enzymes; Peptides; Serine; Sulfides; Threonine | 2007 |
Single amino acid changes in the Nipah and Hendra virus attachment glycoproteins distinguish ephrinB2 from ephrinB3 usage.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Brain; CHO Cells; Cricetinae; Cricetulus; Ephrin-B2; Ephrin-B3; Hendra Virus; Humans; Mice; Molecular Sequence Data; Nipah Virus; Protein Conformation; Protein Interaction Mapping; Serine; Threonine; Viral Envelope Proteins; Virus Internalization | 2007 |
Resistance to deglycosylation by ammonia of IgA1 O-glycopeptides: implications for the beta-elimination of O-glycans linked to serine and threonine.
Topics: Amino Acid Sequence; Ammonia; Animals; Chemistry; Glycopeptides; Glycosylation; Humans; Immunoglobulin A; Models, Chemical; Molecular Sequence Data; Neuraminidase; Peptides; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2007 |
MafA stability in pancreatic beta cells is regulated by glucose and is dependent on its constitutive phosphorylation at multiple sites by glycogen synthase kinase 3.
Topics: Amino Acid Sequence; Animals; Cell Line; DNA Mutational Analysis; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Insulin; Insulin-Secreting Cells; Maf Transcription Factors, Large; Mice; Molecular Sequence Data; Phosphorylation; Proto-Oncogene Proteins c-akt; Sequence Alignment; Serine; Signal Transduction; Threonine | 2007 |
Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76).
Topics: Amino Acid Sequence; ATP-Binding Cassette Transporters; GTPase-Activating Proteins; Humans; Mass Spectrometry; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; ral GTP-Binding Proteins; Sequence Homology, Amino Acid; Serine; Threonine; Urinary Bladder Neoplasms | 2007 |
A sequential program of dual phosphorylation of KaiC as a basis for circadian rhythm in cyanobacteria.
Topics: Bacterial Proteins; Circadian Rhythm; Circadian Rhythm Signaling Peptides and Proteins; Cyanobacteria; Phosphorylation; Serine; Threonine | 2007 |
The regulatory or phosphorylation domain of p120 catenin controls E-cadherin dynamics at the plasma membrane.
Topics: Animals; Binding Sites; Cadherins; Catenins; Cell Adhesion; Cell Adhesion Molecules; Cell Membrane; Delta Catenin; Dimerization; Endocytosis; Humans; Intercellular Junctions; Mice; Phosphoproteins; Phosphorylation; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Protein Transport; Serine; Solubility; Threonine | 2008 |
Dynamics of protein phosphorylation on Ser/Thr/Tyr in Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; Electrophoresis, Gel, Two-Dimensional; Isoelectric Focusing; Phosphorus Radioisotopes; Phosphorylation; Proteins; Serine; Staining and Labeling; Threonine; Tyrosine | 2007 |
Stereoselective syntheses of 4-oxa diaminopimelic acid and its protected derivatives via aziridine ring opening.
Topics: Alanine; Amino Acids; Aziridines; Catalysis; Diaminopimelic Acid; Haemophilus influenzae; Molecular Structure; Racemases and Epimerases; Serine; Stereoisomerism; Sulfides; Threonine | 2007 |
Conformational consequences of protein glycosylation: preparation of O-mannosyl serine and threonine building blocks, and their incorporation into glycopeptide sequences derived from alpha-dystroglycan.
Topics: Carbohydrate Sequence; Circular Dichroism; Dystroglycans; Glycopeptides; Glycosylation; Humans; Mannose; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Serine; Threonine | 2008 |
Nucleocytoplasmic shuttling of BZR1 mediated by phosphorylation is essential in Arabidopsis brassinosteroid signaling.
Topics: 14-3-3 Proteins; Active Transport, Cell Nucleus; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cell Nucleus; DNA-Binding Proteins; Molecular Sequence Data; Mutation; Nuclear Proteins; Phosphoprotein Phosphatases; Phosphorylation; Phytosterols; Protein Binding; Protein Kinases; Protein Structure, Tertiary; Protein Transport; Serine; Signal Transduction; Subcellular Fractions; Threonine | 2007 |
Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Apoptosis; Cells, Cultured; Diabetes Mellitus, Experimental; Endothelium, Vascular; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Mice; Peroxynitrous Acid; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reactive Nitrogen Species; Serine; Signal Transduction; Threonine; Umbilical Veins; Up-Regulation | 2007 |
Disappearance of interfering alkali-metal adducted peaks from matrix-assisted laser desorption/ionization mass spectra of peptides with serine addition to alpha-cyano-4-hydroxycinnamic acid matrix.
Topics: Animals; Cattle; Coumaric Acids; Metals, Alkali; Peptide Fragments; Peptide Mapping; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Threonine | 2007 |
Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation.
Topics: Androstadienes; Animals; Blotting, Western; Cell Line, Tumor; Immunohistochemistry; Immunoprecipitation; Mutation; Neurofibromin 2; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Serine; Threonine; Ubiquitins; Wortmannin | 2007 |
DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
Topics: Alzheimer Disease; Animals; Brain; Cell Line; DNA, Complementary; Down Syndrome; Dyrk Kinases; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Models, Biological; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Serine; tau Proteins; Threonine | 2007 |
EGFR and beta1 integrins utilize different signaling pathways to activate Akt.
Topics: Animals; Cell Adhesion; Cells, Cultured; ErbB Receptors; Focal Adhesion Kinase 1; Integrin beta1; Mice; Models, Biological; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine | 2008 |
Protein kinase C regulates expression and function of inhibitory killer cell Ig-like receptors in NK cells.
Topics: Amino Acid Substitution; Casein Kinase II; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cytotoxicity, Immunologic; Down-Regulation; Glutamic Acid; Humans; Killer Cells, Natural; Phosphorylation; Protein Kinase C; Receptors, KIR; Receptors, KIR3DL1; Serine; Substrate Specificity; Threonine | 2007 |
Site directed mutagenesis of Drosophila flightin disrupts phosphorylation and impairs flight muscle structure and mechanics.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Animals, Genetically Modified; Binding Sites; Drosophila melanogaster; Drosophila Proteins; Filamins; Microscopy, Electron, Transmission; Muscle Contraction; Muscle Proteins; Muscle, Striated; Mutagenesis, Site-Directed; Mutation; Phenotype; Phosphorylation; Sarcomeres; Serine; Threonine; Transgenes; Wings, Animal | 2007 |
Identification of protein phosphorylation sites within Ser/Thr-rich cluster domains using site-directed mutagenesis and hybrid linear quadrupole ion trap Fourier transform ion cyclotron resonance mass spectrometry.
Topics: Amino Acid Sequence; Checkpoint Kinase 2; Chromatography, Liquid; Cyclotrons; Glutamine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Nanotechnology; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Threonine | 2007 |
Site-directed mutagenesis of five conserved residues of subunit i of the cytochrome cbb3 oxidase in Rhodobacter capsulatus.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Bacterial Proteins; Catalysis; Cytochromes c; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Heme; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Subunits; Rhodobacter capsulatus; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine | 2007 |
Hydrolysis of non-cognate aminoacyl-adenylates by a class II aminoacyl-tRNA synthetase lacking an editing domain.
Topics: Adenosine Monophosphate; Binding Sites; Cysteine; Escherichia coli Proteins; Hydrolysis; Protein Structure, Tertiary; RNA Editing; Saccharomyces cerevisiae Proteins; Serine; Serine-tRNA Ligase; Substrate Specificity; Threonine | 2007 |
Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.
Topics: Amino Acid Sequence; Amino Acids; Bacillus subtilis; Bacterial Proteins; Conserved Sequence; Escherichia coli; Evolution, Molecular; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphoproteins; Phosphorylation; Proteome; Serine; Threonine; Tyrosine | 2008 |
Unique anthranilic acid chemistry facilitates profiling and characterization of Ser/Thr-linked sugar chains following hydrazinolysis.
Topics: Carbohydrate Sequence; Carbohydrates; Chromatography, High Pressure Liquid; Hydrazines; Hydrolysis; Molecular Sequence Data; ortho-Aminobenzoates; Reference Standards; Serine; Threonine | 2008 |
O-linked glycosylation ensures the normal conformation of the autotransporter adhesin involved in diffuse adherence.
Topics: Adhesins, Escherichia coli; Bacterial Adhesion; Cell Line; Epithelial Cells; Escherichia coli; Glycosylation; Heptoses; Humans; Mass Spectrometry; Peptide Hydrolases; Peptides; Protein Conformation; Protein Processing, Post-Translational; Sequence Analysis, Protein; Serine; Threonine | 2007 |
Activation of double-stranded RNA-activated protein kinase by mild impairment of oxidative metabolism in neurons.
Topics: Active Transport, Cell Nucleus; Animals; Animals, Newborn; Antioxidants; Brain; Cells, Cultured; eIF-2 Kinase; Enzyme Activation; Eukaryotic Initiation Factor-2; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Oxidative Phosphorylation; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Thiamine Deficiency; Threonine; Tocopherols | 2007 |
Homeodomain-interacting protein kinase-2 (HIPK2) phosphorylates HMGA1a at Ser-35, Thr-52, and Thr-77 and modulates its DNA binding affinity.
Topics: Amino Acid Sequence; Carrier Proteins; CDC2 Protein Kinase; DNA; HMGA1a Protein; HMGA1b Protein; Humans; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Isoforms; Protein Serine-Threonine Kinases; Serine; Threonine | 2007 |
Purification and characterization of serine racemase from a hyperthermophilic archaeon, Pyrobaculum islandicum.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Archaeal Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hydrogen-Ion Concentration; Ions; Models, Genetic; Molecular Sequence Data; Pyrobaculum; Racemases and Epimerases; Recombinant Proteins; Sequence Analysis, Protein; Serine; Stereoisomerism; Substrate Specificity; Threonine | 2008 |
Protein kinase C delta is phosphorylated on five novel Ser/Thr sites following inducible overexpression in human colorectal cancer cells.
Topics: Amino Acid Sequence; Catalytic Domain; Colorectal Neoplasms; Doxycycline; Humans; Mass Spectrometry; Molecular Sequence Data; Phosphorylation; Protein Kinase C-delta; Serine; Threonine | 2007 |
Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators.
Topics: AMP-Activated Protein Kinases; Animals; Binding Sites; GTPase-Activating Proteins; Humans; Immunohistochemistry; Insulin; Insulin-Like Growth Factor I; Multienzyme Complexes; Muscle Fibers, Skeletal; Mutation; Nuclear Proteins; Phosphorylation; Phylogeny; Protein Serine-Threonine Kinases; Rats; Serine; Threonine | 2008 |
Confluence induced threonine41/serine45 phospho-beta-catenin dephosphorylation via ceramide-mediated activation of PP1cgamma.
Topics: beta Catenin; Cell Line, Tumor; Cell Movement; Ceramides; Enzyme Activation; Humans; Isoenzymes; Protein Phosphatase 1; RNA, Small Interfering; Serine; Sphingomyelin Phosphodiesterase; Stereoisomerism; Threonine | 2007 |
Mass-spectrometric identification of proteins detected in forskolin-stimulated Xenopus laevis oocytes using antibody against phospho-(Ser/Thr) cAMP-dependent protein kinase substrate.
Topics: Amino Acid Sequence; Animals; Antibodies; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Female; Mass Spectrometry; Molecular Sequence Data; Oocytes; Peptide Elongation Factor 2; Phosphorylation; Serine; Substrate Specificity; Threonine; Xenopus laevis; Xenopus Proteins | 2007 |
Novel mutation confirms seizure locus SCN1A is also familial hemiplegic migraine locus FHM3.
Topics: Adult; Child, Preschool; DNA Mutational Analysis; Family Health; Female; Humans; Male; Migraine with Aura; Mutation, Missense; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neurologic Examination; Seizures; Serine; Sodium Channels; Threonine | 2007 |
Competitive inhibition of amino acid uptake suppresses chlamydial growth: involvement of the chlamydial amino acid transporter BrnQ.
Topics: Amino Acid Transport Systems; Amino Acids; Bacterial Proteins; Biological Transport; Cell Survival; Chlamydia; Chromatography, High Pressure Liquid; Cycloheximide; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Glycine; HeLa Cells; Humans; Isoleucine; Leucine; Methionine; Microscopy, Confocal; Microscopy, Electron, Transmission; Oligonucleotide Array Sequence Analysis; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; Serine; Sirolimus; Threonine | 2008 |
Thr339-to-serine substitution in rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Binding Sites; Cell Line; Cell Membrane; Humans; Ion Channel Gating; Lysine; Mutagenesis; Protein Binding; Protein Structure, Tertiary; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Serine; Suramin; Threonine | 2007 |
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.
Topics: Amino Acid Sequence; Animals; Catalysis; Cattle; Cell Cycle; DNA Glycosylases; HeLa Cells; Humans; Mice; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Isoforms; Replication Protein A; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Uracil | 2008 |
Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding.
Topics: 14-3-3 Proteins; Binding Sites; Cell Cycle Proteins; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dimerization; Electroporation; Enzyme Activation; Guanine Nucleotide Exchange Factors; Humans; Kidney; Models, Biological; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Proto-Oncogene Proteins c-myc; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; Rho Guanine Nucleotide Exchange Factors; Serine; Threonine; Time Factors; Transfection | 2008 |
Tuning the HNN experiment: generation of serine-threonine check points.
Topics: Animals; Carbon Isotopes; Drosophila; Drosophila Proteins; Methanosarcina; Nuclear Magnetic Resonance, Biomolecular; Serine; Threonine | 2008 |
alpha2 But not alpha1 AMP-activated protein kinase mediates oxidative stress-induced inhibition of retinal pigment epithelium cell phagocytosis of photoreceptor outer segments.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cell Line; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Models, Biological; Multienzyme Complexes; Oxidative Stress; Phagocytosis; Phosphorylation; Photoreceptor Cells; Pigment Epithelium of Eye; Protein Serine-Threonine Kinases; Ribonucleotides; Serine; Threonine | 2008 |
Functional and structural roles of conserved cysteine residues in the carboxyl-terminal domain of the follicle-stimulating hormone receptor in human embryonic kidney 293 cells.
Topics: Alanine; Amino Acid Sequence; Cell Line; Computer Simulation; Cyclic AMP; Cysteine; Humans; Kidney; Lipoylation; Molecular Sequence Data; Mutation; Receptors, FSH; Serine; Threonine | 2008 |
Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep.
Topics: Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Electroencephalography; Electromyography; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; Neuronal Plasticity; Phosphorylation; Rats; Rats, Inbred WKY; Receptors, AMPA; Serine; Sleep; Synapses; Temperature; Threonine; Wakefulness | 2008 |
Induction of actin cytoskeleton rearrangement by methyl okadaate--comparison with okadaic acid.
Topics: Actins; Calcium; Cell Line; Cytoskeleton; Cytosol; Ethers, Cyclic; Humans; Membrane Potentials; Okadaic Acid; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; Serine; Threonine | 2008 |
The mouse and human Ah receptor differ in recognition of LXXLL motifs.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids, Acidic; Animals; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; DNA-Binding Proteins; Glutamine; Humans; Mice; Molecular Sequence Data; Proline; Receptors, Aryl Hydrocarbon; Recombinant Fusion Proteins; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation | 2008 |
Another example of a KEL1 variant red cell phenotype due to a threonine to serine change at position 193 of Kell glycoprotein.
Topics: Anemia, Sickle Cell; Antibodies, Monoclonal; Blood Donors; Blood Transfusion; Genotype; Humans; Immunoglobulin M; Kell Blood-Group System; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Serine; Threonine | 2008 |
PI(3,4,5)P3 and PI(3,4)P2 levels correlate with PKB/akt phosphorylation at Thr308 and Ser473, respectively; PI(3,4)P2 levels determine PKB activity.
Topics: Antibodies; B-Lymphocytes; Cell Line, Tumor; Cell Membrane; Dose-Response Relationship, Immunologic; Enzyme Activation; Humans; Immunoglobulin Fab Fragments; Inositol Polyphosphate 5-Phosphatases; Kinetics; Ligands; Lymphoma, B-Cell; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Receptors, Antigen, B-Cell; Receptors, IgG; Recombinant Fusion Proteins; Second Messenger Systems; Serine; Threonine; Transfection | 2008 |
Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1.
Topics: Angiotensin II; Animals; Antibodies; Carotid Artery Diseases; Catheterization; Cells, Cultured; Disease Models, Animal; Humans; Lymphokines; Muscle, Smooth, Vascular; Mutagenesis; Phosphorylation; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Protein Kinase C; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Serine; Sp1 Transcription Factor; Spectrometry, Mass, Electrospray Ionization; Threonine; Transcription, Genetic; Vasoconstrictor Agents; Zinc Fingers | 2008 |
Characteristics of testicular dysgenesis syndrome and decreased expression of SRY and SOX9 in Frasier syndrome.
Topics: Adult; Cells, Cultured; Child; DNA Mutational Analysis; Down-Regulation; Frasier Syndrome; Genes, Wilms Tumor; Gonadal Dysgenesis; High Mobility Group Proteins; Humans; Lysine; Male; Mutation; RNA, Messenger; Serine; Sex-Determining Region Y Protein; SOX9 Transcription Factor; Spermatogenesis; Testicular Diseases; Threonine; Transcription Factors | 2008 |
Vibrational signatures of protonated, phosphorylated amino acids in the gas phase.
Topics: Gases; Models, Chemical; Molecular Structure; Phosphorylation; Protons; Serine; Spectrophotometry, Infrared; Threonine; Tyrosine; Vibration | 2008 |
Posttranslational modifications on protein kinase c isozymes. Effects of epinephrine and phorbol esters.
Topics: Acetylglucosamine; Animals; Enzyme Activation; Epinephrine; Hepatocytes; Isoenzymes; Male; Mass Spectrometry; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Wistar; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2008 |
Inhibitory effects of ginsenosides from the root of Panax ginseng on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation, and translocation of cytosolic compounds to plasma membrane in human neutrophils.
Topics: Cell Membrane; Cytochromes c; Cytosol; Ginsenosides; Neutrophils; Oxidation-Reduction; Panax; Phosphorylation; Plant Roots; Serine; Superoxides; Threonine; Tyrosine | 2008 |
Effects of protein phosphatase inhibitor calyculin a on the postacrosomal protein serine/threonine phosphorylation state and acrosome reaction in boar spermatozoa incubated with a cAMP analog.
Topics: Acrosome; Acrosome Reaction; Animals; Chlortetracycline; Cyclic AMP; Dichlororibofuranosylbenzimidazole; Enzyme Inhibitors; Male; Marine Toxins; Oxazoles; Phosphorylation; Protein Phosphatase 1; Protein Synthesis Inhibitors; Serine; Sus scrofa; Thionucleotides; Threonine | 2008 |
Chemical derivatization of peptides containing phosphorylated serine/threonine for efficient ionization and quantification in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Algorithms; Computer Simulation; Models, Chemical; Peptides; Phosphorylation; Reproducibility of Results; Sensitivity and Specificity; Serine; Specimen Handling; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2008 |
Effect of glycosylation on the extracellular domain of the Ag43 bacterial autotransporter: enhanced stability and reduced cellular aggregation.
Topics: Adhesins, Bacterial; Adhesins, Escherichia coli; Amino Acid Sequence; Biological Transport; Calcium; Escherichia coli; Escherichia coli Proteins; Glycosylation; Kinetics; Models, Molecular; Molecular Sequence Data; Periplasm; Protein Folding; Protein Structure, Tertiary; Serine; Structure-Activity Relationship; Threonine | 2008 |
Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.
Topics: Catalysis; Cell Line; Humans; Mutagenesis, Site-Directed; Myosin Type II; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Sequence Deletion; Serine; Threonine; TRPM Cation Channels | 2008 |
Charge environments around phosphorylation sites in proteins.
Topics: Binding Sites; Databases, Protein; Models, Molecular; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Proteins; Serine; Threonine; Tyrosine | 2008 |
Blue light-induced autophosphorylation of phototropin is a primary step for signaling.
Topics: Arabidopsis Proteins; Binding Sites; Cryptochromes; Flavoproteins; Kinetics; Light; Phosphorylation; Serine; Signal Transduction; Threonine | 2008 |
Adeno-associated virus transfer of a gene encoding SNAP-25 resistant to botulinum toxin A attenuates neuromuscular paralysis associated with botulism.
Topics: Animals; Botulinum Toxins, Type A; Botulism; Catecholamines; Cells, Cultured; Chromaffin Cells; Dependovirus; Endocytosis; Gene Transfer Techniques; Green Fluorescent Proteins; Muscle, Skeletal; Mutation; Neuromuscular Agents; Neuromuscular Junction; Pseudobulbar Palsy; Rats; Serine; Synaptosomal-Associated Protein 25; Threonine | 2008 |
Roles of two surface residues near the access channel in the substrate recognition by cytochrome P450cam.
Topics: Binding Sites; Camphor 5-Monooxygenase; Kinetics; Models, Biological; Molecular Structure; Mutation; Protein Binding; Serine; Spectrum Analysis; Substrate Specificity; Thermodynamics; Threonine | 2008 |
Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria.
Topics: Amino Acid Sequence; Animals; Betulinic Acid; Cell Death; Cell Line; Cytochromes c; DNA-Binding Proteins; Down-Regulation; Humans; Membrane Potential, Mitochondrial; Mice; Mitochondria; Molecular Sequence Data; Oxidoreductases; Pentacyclic Triterpenes; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Serine; Threonine; Triterpenes; Tumor Suppressor Protein p53 | 2008 |
ORF018R, a highly abundant virion protein from Singapore grouper iridovirus, is involved in serine/threonine phosphorylation and virion assembly.
Topics: Animals; Cell Nucleus; Cells, Cultured; Cytoplasm; Electrophoresis, Gel, Two-Dimensional; Fishes; Gene Silencing; Iridovirus; Isoelectric Point; Microscopy, Fluorescence; Molecular Weight; Phosphorylation; Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Viral Proteins; Virus Assembly | 2008 |
Preparation and application of polyclonal and monoclonal sequence-specific anti-phosphoamino acid antibodies.
Topics: Adjuvants, Immunologic; Amino Acid Sequence; Animals; Antibodies; Antibodies, Monoclonal; Antigens; Chromatography, Affinity; Cross-Linking Reagents; Culture Media, Conditioned; Humans; Mice; Molecular Sequence Data; Peptides; Phosphoamino Acids; Serine; Threonine; Tyrosine | 2004 |
[Plasmodium falciparum chloroquine and pyrimethamine resistance monitoring network with molecular tools in the Niger River valley, Republic of Niger].
Topics: Animals; Antigens, Protozoan; Antimalarials; Asparagine; Biomarkers; Chloroquine; Communicable Disease Control; Drug Resistance; Humans; Lysine; Membrane Transport Proteins; Mutation; Niger; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Serine; Tetrahydrofolate Dehydrogenase; Threonine | 2008 |
Preparation and analysis of phosphorylated proteins.
Topics: Animals; Binding Sites; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Ligands; Mice; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; T-Lymphocytes; Threonine; Time Factors; Tyrosine | 2001 |
Iodine-mediated glycosylation en route to mucin-related glyco-aminoacids and glycopeptides.
Topics: Acetylgalactosamine; Amino Acids; Glycopeptides; Glycosylation; Iodine; Mucins; Serine; Threonine | 2008 |
Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53-induced apoptosis.
Topics: Adenoviridae; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression; Gene Expression Regulation; Genetic Therapy; Genetic Vectors; Humans; Immunoprecipitation; Oligonucleotide Array Sequence Analysis; Phosphorylation; Polymerase Chain Reaction; Serine; Threonine; Tumor Suppressor Protein p53 | 2008 |
Truncation of human dopamine transporter by protease calpain.
Topics: Amino Acid Sequence; Animals; Calpain; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Female; Humans; Peptide Fragments; Protein Kinase C; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors for Activated C Kinase; Receptors, Cell Surface; Receptors, Dopamine D2; Recombinant Proteins; Serine; Synaptosomes; Threonine | 2008 |
Thr308 determines Akt1 nuclear localization in insulin-stimulated keratinocytes.
Topics: Animals; Cell Nucleus; Cells, Cultured; Cytoplasm; Enzyme Activation; Female; Insulin; Isoenzymes; Keratinocytes; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Serine; Skin; Threonine; Transfection | 2008 |
Influence of shifting positions of Ser, Thr, and Cys residues in prenisin on the efficiency of modification reactions and on the antimicrobial activities of the modified prepeptides.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Binding Sites; Cysteine; Lactococcus lactis; Molecular Sequence Data; Nisin; Peptides; Plasmids; Protein Precursors; Protein Sorting Signals; Serine; Threonine | 2008 |
Phosphorylation and kinetics of mammalian cytochrome c oxidase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Cattle; Electron Transport Complex IV; Kinetics; Mitochondria, Heart; Myocardium; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine | 2008 |
O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic beta cells.
Topics: Acetylglucosamine; Alloxan; Animals; Apoptosis; Cell Line; Glucosamine; Glucose; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; Mannitol; Mice; N-Acetylglucosaminyltransferases; Point Mutation; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Serine; Threonine | 2008 |
Protonation and conformational dynamics of GFP mutants by two-photon excitation fluorescence correlation spectroscopy.
Topics: Computer Simulation; Glutamic Acid; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Luminescent Agents; Mutation; Photons; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Threonine | 2008 |
Adaptational modification of serine and threonine metabolism in the liver to essential amino acid deficiency in rats.
Topics: Amino Acids, Essential; Animals; Diet; Food, Formulated; Gene Expression; L-Serine Dehydratase; Liver; Phosphoglycerate Dehydrogenase; Rats; Rats, Wistar; RNA, Messenger; Serine; Threonine | 2009 |
Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling.
Topics: Animals; Antibodies; beta Catenin; Catalytic Domain; Cell Proliferation; Colonic Neoplasms; Female; Fibroblast Growth Factors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HCT116 Cells; Humans; Mice; Mice, Nude; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 4; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2008 |
Constitutively active Akt induces enhanced myelination in the CNS.
Topics: Age Factors; Animals; Bromodeoxyuridine; Cell Death; Cell Proliferation; Central Nervous System; Gene Expression Regulation; Green Fluorescent Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Myelin Proteolipid Protein; Myelin Sheath; Oligodendroglia; Oncogene Protein v-akt; Optic Nerve; Sciatic Nerve; Serine; Threonine | 2008 |
Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cadherins; Cell Adhesion Molecules; Cell Line; Drosophila melanogaster; Drosophila Proteins; Electrophoretic Mobility Shift Assay; Glycosylation; Golgi Apparatus; Kinetics; Membrane Glycoproteins; Molecular Sequence Data; Mutant Proteins; Phosphorylation; Protein Kinases; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine | 2008 |
Experimental and theoretical investigation of the decomposition of lithiated hydroxyl side-chain amino acids.
Topics: Carbon Dioxide; Cations; Computational Biology; Ligands; Lithium; Mass Spectrometry; Models, Chemical; Models, Statistical; Molecular Conformation; Molecular Structure; Quantum Theory; Serine; Software; Threonine; Water | 2008 |
Experimental and theoretical investigation of alkali metal cation interactions with hydroxyl side-chain amino acids.
Topics: Amino Acids; Cations; Chemistry, Physical; Hydroxyl Radical; Ions; Mass Spectrometry; Metals, Alkali; Models, Statistical; Molecular Structure; Serine; Software; Solvents; Temperature; Threonine; Xenon | 2008 |
The Ser/Thr/Tyr phosphoproteome of Lactococcus lactis IL1403 reveals multiply phosphorylated proteins.
Topics: Amino Acid Sequence; Bacterial Proteins; Glycolysis; Lactococcus lactis; Phosphopeptides; Phosphorylation; Proteome; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2008 |
Importance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavage.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Geobacillus stearothermophilus; Glycine; Glycine Hydroxymethyltransferase; Models, Molecular; Protein Binding; Pyridoxal Phosphate; Serine; Stereoisomerism; Tetrahydrofolates; Threonine; Tyrosine | 2008 |
Site-specific radical directed dissociation of peptides at phosphorylated residues.
Topics: Free Radicals; Naphthalenes; Peptides; Phosphorylation; Photochemistry; Serine; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Threonine | 2008 |
Chances and pitfalls of chemical cross-linking with amine-reactive N-hydroxysuccinimide esters.
Topics: Amino Acid Sequence; Amino Acids; Cross-Linking Reagents; Esters; Laminin; Lysine; Molecular Sequence Data; Peptides; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinimides; Threonine; Tyrosine | 2008 |
A potential role for Drosophila mucins in development and physiology.
Topics: Animals; Drosophila; Drosophila Proteins; Embryonic Development; Gene Expression Regulation, Developmental; Glycosylation; In Situ Hybridization; Mucins; Serine; Threonine | 2008 |
Phytic acid increases mucin and endogenous amino acid losses from the gastrointestinal tract of chickens.
Topics: Amino Acids; Animal Feed; Animals; Biomarkers; Chickens; Digestion; Feces; Gastrointestinal Tract; Male; Mucins; N-Acetylneuraminic Acid; Phytic Acid; Proline; Random Allocation; Serine; Threonine | 2009 |
Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Axin Protein; Cell Line; Dishevelled Proteins; Frizzled Receptors; Humans; LDL-Receptor Related Proteins; Low Density Lipoprotein Receptor-Related Protein-6; Mice; Minor Histocompatibility Antigens; Models, Biological; Phosphatidylinositol 4,5-Diphosphate; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Repressor Proteins; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Wnt Proteins; Wnt3 Protein; Wnt3A Protein; Xenopus; Xenopus Proteins | 2008 |
Extracellular signal-regulated kinase 2 (ERK2) phosphorylation sites and docking domain on the nuclear pore complex protein Tpr cooperatively regulate ERK2-Tpr interaction.
Topics: Animals; Chlorocebus aethiops; COS Cells; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinase 8; Nuclear Pore; Nuclear Pore Complex Proteins; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Serine; Threonine | 2008 |
Phosphorylation by p38 MAP kinase is required for E2F1 degradation and keratinocyte differentiation.
Topics: Animals; Cell Differentiation; Cell Line; DNA Mutational Analysis; E2F1 Transcription Factor; Keratinocytes; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Sequence Deletion; Serine; Threonine | 2009 |
Stereoselective cyclopropanation of serine- and threonine-derived oxazines to access new morpholine-based scaffolds.
Topics: Catalysis; Cyclopropanes; Hydrogen; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Morpholines; Serine; Stereoisomerism; Threonine | 2008 |
Characteristic negative ion fragmentations of deprotonated peptides containing post-translational modifications: mono-phosphorylated Ser, Thr and Tyr. A joint experimental and theoretical study.
Topics: Amino Acid Sequence; Molecular Sequence Data; Peptides; Phosphorylation; Protein Processing, Post-Translational; Protons; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Tyrosine | 2008 |
Identification of new, well-populated amino-acid sidechain rotamers involving hydroxyl-hydrogen atoms and sulfhydryl-hydrogen atoms.
Topics: Amino Acids; Crystallography, X-Ray; Cysteine; Hydrogen; Hydrogen Bonding; Hydroxyl Radical; Protein Conformation; Protein Structure, Secondary; Serine; Sulfhydryl Compounds; Threonine; Tyrosine | 2008 |
Inactivation of HDAC5 by SIK1 in AICAR-treated C2C12 myoblasts.
Topics: Aminoimidazole Carboxamide; Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Histone Deacetylase Inhibitors; Histone Deacetylases; MEF2 Transcription Factors; Mice; Myoblasts; Myogenic Regulatory Factors; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Ribonucleotides; Serine; Signal Transduction; Threonine; Trans-Activators; Transcription Factors | 2009 |
Structural basis for the complete loss of GSK3beta catalytic activity due to R96 mutation investigated by molecular dynamics study.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Arginine; Catalysis; Catalytic Domain; Computer Simulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Models, Molecular; Mutagenesis; Mutation; Phosphorylation; Protein Binding; Protein Conformation; Serine; Structure-Activity Relationship; Thermodynamics; Threonine | 2009 |
Acute ethanol challenge inhibits glycogen synthase kinase-3beta in the rat prefrontal cortex.
Topics: Animals; Central Nervous System Depressants; Ethanol; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mitogen-Activated Protein Kinase 3; Nucleus Accumbens; Oncogene Protein v-akt; Phosphorylation; Prefrontal Cortex; Rats; Serine; Threonine | 2009 |
Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway.
Topics: Binding Sites; Casein Kinase I; Dipeptides; Escherichia coli; Glucose; Glycogen Synthase Kinase 3; Mass Spectrometry; Phosphorylation; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine; Ubiquitin-Protein Ligases | 2008 |
Site-selective intramolecular hydrogen-bonding interactions in phosphorylated serine and threonine dipeptides.
Topics: Circular Dichroism; Dipeptides; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Phosphorylation; Serine; Spectrophotometry, Infrared; Threonine | 2008 |
NetPhosBac - a predictor for Ser/Thr phosphorylation sites in bacterial proteins.
Topics: Algorithms; Animals; Bacillus subtilis; Bacterial Proteins; Databases, Protein; Escherichia coli; Escherichia coli Proteins; Models, Chemical; Neural Networks, Computer; Phosphorylation; Phosphotransferases; Serine; Threonine | 2009 |
Search for inhibitors of bacterial and human protein kinases among derivatives of diazepines[1,4] annelated with maleimide and indole cycles.
Topics: Chemistry, Pharmaceutical; Humans; Indoles; Inhibitory Concentration 50; Maleimides; Models, Chemical; Molecular Conformation; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Recombinant Proteins; Serine; Streptomyces lividans; Thiourea; Threonine | 2008 |
L-Serine lowers while glycine increases blood pressure in chronic L-NAME-treated and spontaneously hypertensive rats.
Topics: Animals; Apamin; Blood Pressure; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Potassium Channels, Calcium-Activated; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Serine; Threonine | 2008 |
S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.
Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Antineoplastic Agents; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Chromones; Cyclin B; Enzyme Inhibitors; Humans; Megakaryocytes; Morpholines; Nocodazole; Phosphoproteins; Phosphorylation; Polyploidy; Protein Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Sirolimus; Tetradecanoylphorbol Acetate; Threonine; TOR Serine-Threonine Kinases; Wortmannin | 2009 |
O-GlcNAc modification of Sp1 inhibits the functional interaction between Sp1 and Oct1.
Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Cell Line; Humans; Mice; Molecular Sequence Data; Organic Cation Transporter 1; Promoter Regions, Genetic; Protein Binding; RNA, Small Nuclear; Serine; Sp1 Transcription Factor; Threonine; Transcription, Genetic | 2009 |
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Cell Line; Glucose; Humans; Muscles; Niacinamide; Oxidation-Reduction; Phosphorylation; Pyruvic Acid; Quercetin; Rats; Resveratrol; Serine; Sirtuin 1; Sirtuins; Stilbenes; Threonine | 2009 |
SCF(Fbxw7/hCdc4) targets cyclin E2 for ubiquitin-dependent proteolysis.
Topics: Binding Sites; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cyclin E; Cyclins; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; HeLa Cells; Humans; Mutagenesis, Site-Directed; Neoplasms; Oncogene Proteins; Phosphorylation; Recombinant Proteins; RNA Interference; Serine; Substrate Specificity; Threonine; Ubiquitin; Ubiquitin-Protein Ligases | 2009 |
Crystal structure of the parasporin-2 Bacillus thuringiensis toxin that recognizes cancer cells.
Topics: Amino Acid Sequence; Bacillus thuringiensis; Binding Sites; Crystallography, X-Ray; Databases, Protein; Drug Screening Assays, Antitumor; Endotoxins; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Folding; Serine; Threonine | 2009 |
Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemistry, Pharmaceutical; Crystallography, X-Ray; Cytochrome P-450 CYP2C9; Diabetes Mellitus, Type 2; Drug Design; Glycine; Glycogen Phosphorylase; Humans; Imides; Inhibitory Concentration 50; Liver; Models, Chemical; ortho-Aminobenzoates; Rats; Serine; Threonine | 2009 |
Identification of in vitro phosphorylation sites in the Arabidopsis thaliana somatic embryogenesis receptor-like kinases.
Topics: Arabidopsis; Arabidopsis Proteins; Catalytic Domain; Escherichia coli; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Repetitive Sequences, Amino Acid; Serine; Signal Transduction; Tandem Mass Spectrometry; Threonine | 2009 |
Phosphorylation regulates SIRT1 function.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Catalytic Domain; CDC2 Protein Kinase; Cells, Cultured; Cyclin B; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Mice; Models, Molecular; Phosphorylation; Protein Binding; Serine; Sirtuin 1; Sirtuins; Threonine | 2008 |
Presentation of cytosolically stable peptides by HLA-B27 is not dependent on the canonic interactions of N-terminal basic residues in the A pocket.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antigen Presentation; Cell Line, Tumor; Cytosol; Gene Expression Regulation; Glutamic Acid; HLA-B Antigens; HLA-B27 Antigen; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ligands; Peptide Fragments; Protein Binding; Serine; Signal Transduction; Thermodynamics; Threonine; Tryptophan | 2009 |
RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Melanins; Neurons; Oncogene Protein v-akt; Oxidopamine; Parkinson Disease; Phosphorylation; Rats; Serine; Substantia Nigra; Superior Cervical Ganglion; Sympatholytics; Threonine; Time Factors; Transcription Factors; Transfection | 2008 |
D-serine induces lipid and protein oxidative damage and decreases glutathione levels in brain cortex of rats.
Topics: Alanine; Analysis of Variance; Animals; Antioxidants; Cerebral Cortex; Glutathione; Lipid Peroxidation; Luminescence; Oxidants; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Serine; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Threonine | 2009 |
Long-term effects of prenatal hypoxia on endothelium-dependent relaxation responses in pulmonary arteries of adult sheep.
Topics: Acetylcholine; Animals; Calcimycin; Calmodulin; Caveolin 1; Endothelium, Vascular; Female; Fetal Hypoxia; HSP90 Heat-Shock Proteins; In Vitro Techniques; Nitric Oxide Synthase Type III; Nitroso Compounds; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Artery; Serine; Sheep; Threonine; Vasodilation | 2009 |
Mutational analysis of the cytoplasmic domain of CEACAM1-4L in humanized mammary glands reveals key residues involved in lumen formation: stimulation by Thr-457 and inhibition by Ser-461.
Topics: Adipose Tissue; Alternative Splicing; Amino Acid Sequence; Animals; Antigens, CD; Cell Adhesion Molecules; Cell Line; Cells, Cultured; DNA Mutational Analysis; Humans; Mammary Glands, Human; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Sequence Data; Protein Isoforms; Protein Structure, Tertiary; Serine; Threonine | 2009 |
The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukaemia.
Topics: Adolescent; Adult; Apoptosis; Cell Proliferation; Cytogenetic Analysis; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phosphorylation; Prognosis; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Risk Assessment; Serine; Survival Rate; Threonine; Young Adult | 2009 |
Site-specific regulation of CA(V)2.2 channels by protein kinase C isozymes betaII and epsilon.
Topics: Animals; Aspartic Acid; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation; Guanosine Diphosphate; Membrane Potentials; Microinjections; Mutation; Oocytes; Patch-Clamp Techniques; Phorbol Esters; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Structure, Tertiary; RNA, Small Interfering; Serine; Thionucleotides; Threonine; Xenopus laevis; Xenopus Proteins | 2009 |
Structural basis of glyphosate resistance resulting from the double mutation Thr97 -> Ile and Pro101 -> Ser in 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Binding Sites; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Glycine; Glyphosate; Isoleucine; Kinetics; Models, Chemical; Molecular Conformation; Mutation; Proline; Serine; Threonine | 2009 |
NMR structure of a complex formed by the carboxyl-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 phosphatase.
Topics: Amino Acid Sequence; Binding Sites; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phosphoprotein Phosphatases; Phosphorylation; Protein Binding; Protein Structure, Tertiary; RNA Polymerase II; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Thermodynamics; Threonine; Transcription Factors, TFII | 2009 |
Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation.
Topics: Crystallography, X-Ray; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; p300-CBP Transcription Factors; Phosphorylation; Protein Binding; Protein Interaction Domains and Motifs; Protein Interaction Mapping; Protein Kinases; Protein Structure, Quaternary; Serine; Thermodynamics; Threonine; Tumor Suppressor Protein p53 | 2009 |
Alzheimer's disease-specific tau phosphorylation is induced by herpes simplex virus type 1.
Topics: Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Glycogen Synthase Kinase 3; Herpesvirus 1, Human; Humans; Infections; Neuroblastoma; Phosphorylation; Serine; tau Proteins; Threonine | 2009 |
Essential role of one-carbon metabolism and Gcn4p and Bas1p transcriptional regulators during adaptation to anaerobic growth of Saccharomyces cerevisiae.
Topics: Basic-Leucine Zipper Transcription Factors; Cell Proliferation; Cell Wall; DNA-Binding Proteins; Gene Expression Regulation, Fungal; Genes, Reporter; Genotype; Glycine; Models, Biological; Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Subcellular Fractions; Threonine; Trans-Activators; Transcription Factors; Transcription, Genetic | 2009 |
A role for calmodulin-stimulated adenylyl cyclases in cocaine sensitization.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Behavior, Animal; Calcium; Calmodulin; Cocaine; Corpus Striatum; CREB-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Signal Transduction; Threonine; Up-Regulation | 2009 |
CpgA, EF-Tu and the stressosome protein YezB are substrates of the Ser/Thr kinase/phosphatase couple, PrkC/PrpC, in Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; Escherichia coli; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Substrate Specificity; Threonine | 2009 |
PARK11 gene (GIGYF2) variants Asn56Ser and Asn457Thr are not pathogenic for Parkinson's disease.
Topics: Aged; Asparagine; Austria; Carrier Proteins; DNA Mutational Analysis; Egypt; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germany; Humans; Male; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Serine; Threonine; White People | 2009 |
cAMP enhances estrogen-related receptor alpha (ERRalpha) transcriptional activity at the SP-A promoter by increasing its interaction with protein kinase A and steroid receptor coactivator 2 (SRC-2).
Topics: Animals; Cell Nucleus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; ERRalpha Estrogen-Related Receptor; Fetus; Genome, Human; Humans; Isoquinolines; Lung; Mice; Nuclear Receptor Coactivator 2; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Transport; Pulmonary Surfactant-Associated Protein A; Receptors, Estrogen; Response Elements; Serine; Sulfonamides; Threonine; Transcription, Genetic | 2009 |
Ser/Thr/Tyr protein phosphorylation in the archaeon Halobacterium salinarum--a representative of the third domain of life.
Topics: Amino Acids; Archaea; Biological Evolution; Genome, Bacterial; Halobacterium salinarum; Phosphorylation; Proteomics; Serine; Signal Transduction; Threonine; Tyrosine | 2009 |
The role of the Ser/Thr cluster in the phosphorylation of PPPSP motifs in Wnt coreceptors.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; beta Catenin; Casein Kinase I; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; LDL-Receptor Related Proteins; Low Density Lipoprotein Receptor-Related Protein-5; Low Density Lipoprotein Receptor-Related Protein-6; Mice; Molecular Sequence Data; Phosphorylation; Receptors, LDL; Serine; Threonine; Wnt Proteins | 2009 |
p97/valosin-containing protein (VCP) is highly modulated by phosphorylation and acetylation.
Topics: Acetylation; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Blotting, Western; Cell Cycle Proteins; Cell Line; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Humans; Kinetics; Lysine; Mass Spectrometry; Molecular Sequence Data; Mutation; Phosphorylation; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spodoptera; Threonine; Tyrosine; Valosin Containing Protein | 2009 |
FXYD1 phosphorylation in vitro and in adult rat cardiac myocytes: threonine 69 is a novel substrate for protein kinase C.
Topics: Animals; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dogs; Enzyme Activation; Humans; Male; Membrane Potentials; Membrane Proteins; Myocytes, Cardiac; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Cell Surface; Recombinant Proteins; Serine; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Threonine; Time Factors | 2009 |
Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.
Topics: Aging; Alanine; Animals; Aspartic Acid; Brain Ischemia; Brain Stem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Potassium; Serine; Taurine; Threonine | 2009 |
Weak functional constraints on phosphoproteomes.
Topics: Animals; Binding Sites; Evolution, Molecular; Humans; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Proteome; Serine; Threonine; Tyrosine | 2009 |
Phosphorylated serine and threonine residues promote site-specific fragmentation of singly charged, arginine-containing peptide ions.
Topics: Arginine; Ions; Oryza; Phosphopeptides; Phosphorylation; Plant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2009 |
Regulatory autophosphorylation sites on protein kinase C-delta at threonine-141 and threonine-295.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Biocatalysis; Chlorocebus aethiops; COS Cells; Down-Regulation; Enzyme Activation; Humans; Mice; Molecular Sequence Data; Phosphorylation; Protein Kinase C-delta; Rats; Serine; Threonine | 2009 |
Prenatal stress alters glutamatergic system responsiveness in adult rat prefrontal cortex.
Topics: Analysis of Variance; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Female; Glutamic Acid; Hippocampus; Male; Phosphorylation; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Restraint, Physical; Serine; Sex Factors; Stress, Psychological; Swimming; Threonine | 2009 |
New insights into mTOR signaling: mTORC2 and beyond.
Topics: Amino Acid Sequence; Animals; Cell Proliferation; Humans; Immediate-Early Proteins; Models, Biological; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; TOR Serine-Threonine Kinases; Transcription Factors | 2009 |
Ser/Thr/Tyr phosphoproteome analysis of pathogenic and non-pathogenic Pseudomonas species.
Topics: Amino Acids; Bacterial Proteins; Chromatography, Liquid; Cyclic GMP; Mass Spectrometry; Phosphoamino Acids; Phosphopeptides; Phosphorylation; Protein Kinases; Proteome; Pseudomonas aeruginosa; Pseudomonas putida; Serine; Signal Transduction; Threonine; Tyrosine | 2009 |
Preparation of a new crown ether-based chiral stationary phase containing thioester linkage for the liquid chromatographic separation of enantiomers.
Topics: Amines; Amino Acids; Amino Alcohols; Chromatography, Liquid; Crown Ethers; Methionine; Molecular Structure; Serine; Stereoisomerism; Threonine | 2009 |
Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner.
Topics: Animals; Animals, Newborn; Apoptosis; Carrier Proteins; Cells, Cultured; Child, Preschool; Dose-Response Relationship, Drug; Embryo, Mammalian; Endoplasmic Reticulum; Flow Cytometry; Gene Expression Regulation; Heme Oxygenase-1; Hippocampus; Humans; Lactones; Male; Mice; Mice, Transgenic; Mitochondria; Neurons; Oxidative Stress; Phosphotransferases (Alcohol Group Acceptor); Reactive Oxygen Species; RNA, Small Interfering; Serine; Sesquiterpenes; Threonine; Time Factors; TOR Serine-Threonine Kinases; Transcription Factor CHOP; Transduction, Genetic; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Tunicamycin | 2009 |
Negative ion fragmentations of deprotonated peptides containing post-translational modifications: diphosphorylated systems containing Ser, Thr and Tyr. A characteristic phosphate/phosphate cyclisation. A joint experimental and theoretical study.
Topics: Cyclization; Ions; Peptides; Phosphates; Phosphorylation; Protein Processing, Post-Translational; Serine; Spectrum Analysis; Tandem Mass Spectrometry; Threonine; Tyrosine | 2009 |
Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Calpain; Cysteine Proteinase Inhibitors; Cytosol; Escherichia coli; Escherichia coli Proteins; Glutathione Transferase; Half-Life; HeLa Cells; Humans; Leupeptins; Molecular Sequence Data; NIMA-Interacting Peptidylprolyl Isomerase; Okadaic Acid; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Recombinant Proteins; Serine; Sulfotransferases; Threonine; Transfection; Two-Hybrid System Techniques | 2009 |
Radical-driven dissociation of odd-electron peptide radical ions produced in 157 nm photodissociation.
Topics: Amides; Amino Acids; Deuterium Exchange Measurement; Electrons; Free Radicals; Hydrogen; Ions; Kinetics; Mass Spectrometry; Peptides; Photochemical Processes; Protein Structure, Secondary; Serine; Threonine | 2009 |
Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1.
Topics: Amino Acid Substitution; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Bacillus; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Circular Dichroism; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Malates; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Nitro Compounds; Propionates; Protein Structure, Tertiary; Serine; Substrate Specificity; Threonine | 2009 |
Occludin phosphorylation in regulation of epithelial tight junctions.
Topics: Animals; Binding Sites; Epithelium; Humans; Membrane Proteins; Mice; Mice, Knockout; Occludin; Phosphorylation; Serine; Threonine; Tight Junctions; Tyrosine | 2009 |
Nonprimed and DYRK1A-primed GSK3 beta-phosphorylation sites on MAP1B regulate microtubule dynamics in growing axons.
Topics: Age Factors; Animals; Axons; Cerebral Cortex; Chlorocebus aethiops; COS Cells; Dyrk Kinases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mass Spectrometry; Mice; Microtubule-Associated Proteins; Microtubules; Mutation; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Recombinant Fusion Proteins; RNA Interference; Serine; Spinal Cord; Threonine; Transfection | 2009 |
Suppression of nonhomologous end joining repair by overexpression of HMGA2.
Topics: Animals; Antigens, Nuclear; Blotting, Western; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA Breaks, Double-Stranded; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Gene Expression; HeLa Cells; Histones; HMGA2 Protein; Humans; Ku Autoantigen; Phosphorylation; Recombination, Genetic; Serine; Threonine; Translocation, Genetic; X-Rays | 2009 |
Site-specific phosphorylation regulates human T-cell leukemia virus type 2 Rex function in vivo.
Topics: Amino Acid Sequence; Cell Nucleus; Chromatography, Affinity; Cytoplasm; Gene Expression Regulation, Viral; Gene Products, rex; Human T-lymphotropic virus 2; Humans; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Serine; Tandem Mass Spectrometry; Threonine | 2009 |
Syntheses of mucin-type O-glycopeptides and oligosaccharides using transglycosylation and reverse-hydrolysis activities of Bifidobacterium endo-alpha-N-acetylgalactosaminidase.
Topics: alpha-N-Acetylgalactosaminidase; Amino Acid Sequence; Animals; Bifidobacterium; Galactosamine; Gastric Mucins; Glycopeptides; Glycosylation; Hydrolysis; Molecular Sequence Data; Oligosaccharides; Serine; Sus scrofa; Threonine | 2010 |
Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1.
Topics: Aldosterone; Animals; Diuresis; Hyperkalemia; Immediate-Early Proteins; Kidney; Mice; Mice, Knockout; Phosphorylation; Potassium, Dietary; Protein Serine-Threonine Kinases; Receptors, Drug; Serine; Sodium Chloride, Dietary; Solute Carrier Family 12, Member 3; Symporters; Threonine | 2009 |
Protein kinase G phosphorylates mosquito-borne flavivirus NS5.
Topics: Animals; Chlorocebus aethiops; Cyclic GMP-Dependent Protein Kinases; Dengue Virus; Flavivirus; Histidine; Mass Spectrometry; Phosphorylation; Serine; Threonine; Ticks; Viral Nonstructural Proteins; Virus Replication; Yellow fever virus | 2009 |
Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Catalysis; Catalytic Domain; Cell Line; Cell Line, Tumor; Conserved Sequence; Drosophila melanogaster; Drosophila Proteins; Enzyme Activation; Evolution, Molecular; Humans; Immunoblotting; Immunoprecipitation; MAP Kinase Kinase Kinase 5; Mitochondrial Proteins; Molecular Sequence Data; Mutation; Phosphoprotein Phosphatases; Phosphorylation; Sequence Homology, Amino Acid; Serine; Threonine | 2009 |
Par-4 is an essential downstream target of DAP-like kinase (Dlk) in Dlk/Par-4-mediated apoptosis.
Topics: Amino Acid Sequence; Amino Acids, Acidic; Animals; Apoptosis; Apoptosis Regulatory Proteins; Biocatalysis; Calcium-Calmodulin-Dependent Protein Kinases; Death-Associated Protein Kinases; Lysophospholipids; Molecular Mimicry; Molecular Sequence Data; Phosphorylation; Protein Binding; Rats; Serine; Substrate Specificity; Threonine; Time Factors | 2009 |
Using expressed protein ligation to probe the substrate specificity of lantibiotic synthetases.
Topics: Amino Acids; Analytic Sample Preparation Methods; Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; Cyclization; Cysteine; Dehydration; Gene Expression; Hydro-Lyases; Inteins; Ligases; Molecular Structure; Peptides; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Threonine | 2009 |
Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells.
Topics: Casein Kinase II; Cell Line; Cell Survival; Enzyme Activation; HSP90 Heat-Shock Proteins; Humans; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2009 |
Moderate intensity of regular exercise improves cardiac SR Ca2+ uptake activity in ovariectomized rats.
Topics: Animals; Biological Transport; Calcium; Calcium-Binding Proteins; Calsequestrin; Carrier Proteins; Female; Heart Ventricles; Myocardium; Ovariectomy; Phosphorylation; Physical Exertion; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Threonine | 2009 |
TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling.
Topics: Anthracenes; Butadienes; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; HeLa Cells; Humans; Imidazoles; Lactones; MAP Kinase Kinase Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinazolines; Resorcinols; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha | 2009 |
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Topics: Actins; Amino Acid Sequence; Binding Sites; Biological Transport; Cytokines; Endocytosis; Extracellular Signal-Regulated MAP Kinases; Humans; Jurkat Cells; Microtubules; Models, Biological; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Binding; Protein Interaction Mapping; Proteomics; Receptors, Antigen, T-Cell; RNA Splicing; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2009 |
Human SMAD4 is phosphorylated at Thr9 and Ser138 by interacting with NLK.
Topics: Binding Sites; Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Serine; Smad4 Protein; Threonine; Two-Hybrid System Techniques | 2010 |
Impaired contractile function and calcium handling in hearts of cardiac-specific calcineurin b1-deficient mice.
Topics: Aging; Animals; Calcineurin; Calcium Signaling; Calcium-Binding Proteins; Cardiomyopathies; Cardiotonic Agents; Dobutamine; Fatty Acids; Genotype; Heart Ventricles; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Mitochondria, Heart; Muscle Proteins; Myocardial Contraction; Myocardium; Oxidation-Reduction; Phenotype; Phosphorylation; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Sodium-Calcium Exchanger; Threonine; Ventricular Dysfunction, Left; Ventricular Remodeling | 2009 |
Phosphorylated proteins of the mammalian mitochondrial ribosome: implications in protein synthesis.
Topics: Amino Acid Sequence; Animals; Apoptosis; Cattle; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Escherichia coli Proteins; Immunoblotting; Mammals; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Structure, Tertiary; Proteomics; Ribosomal Proteins; Sequence Alignment; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2009 |
Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress.
Topics: Cell Line; DNA Damage; DNA Repair; DNA Replication; Humans; Hydroxyurea; Mitosis; Phosphorylation; Protein Phosphatase 2; Replication Protein A; Serine; Stress, Physiological; Threonine; Ultraviolet Rays | 2009 |
Mutations of Lysine 47 in cyclodextrin glycosyltransferase from Paenibacillus macerans enhance beta-cyclodextrin specificity.
Topics: alpha-Cyclodextrins; beta-Cyclodextrins; Glucosyltransferases; Leucine; Lysine; Mutagenesis, Site-Directed; Paenibacillus; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine | 2009 |
Activation of the PDK-1/Akt/eNOS pathway involved in aortic endothelial function differs between hyperinsulinemic and insulin-deficient diabetic rats.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Acetylcholine; Animals; Aorta; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Hyperinsulinism; Inositol; Insulin; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Signal Transduction; Threonine; Vasodilation; Vasodilator Agents | 2009 |
Tyrosine and serine phosphorylation regulate the conformation and subsequent threonine phosphorylation of the L1 cytoplasmic domain.
Topics: Amino Acid Sequence; Antibodies, Phospho-Specific; Casein Kinase II; Cytoplasm; Epitopes; Humans; Molecular Sequence Data; Mutation; Neural Cell Adhesion Molecule L1; Phosphorylation; Protein Folding; Protein Kinase C-alpha; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Threonine; Tyrosine | 2009 |
Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Antibiotics, Antineoplastic; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromones; Enzyme Activation; Fibronectins; Glioblastoma; Humans; Morpholines; Multiprotein Complexes; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Protein Kinases; Proteins; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; Regulatory-Associated Protein of mTOR; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; Serine; Signal Transduction; Sirolimus; STAT3 Transcription Factor; Threonine; Time Factors; TOR Serine-Threonine Kinases | 2009 |
Controlling peptide folding with repulsive interactions between phosphorylated amino acids and tryptophan.
Topics: Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorylation; Phosphoserine; Protein Folding; Protein Processing, Post-Translational; Serine; Threonine; Tryptophan; Tyrosine | 2009 |
Schizosaccharomyces pombe Cds1Chk2 regulates homologous recombination at stalled replication forks through the phosphorylation of recombination protein Rad60.
Topics: Cell Cycle Proteins; Cell Nucleus; Checkpoint Kinase 2; Chromosomal Proteins, Non-Histone; DNA Damage; DNA Replication; DNA, Ribosomal; Hydroxyurea; Microbial Viability; Mutagens; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; Recombination, Genetic; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Serine; Threonine | 2009 |
Influence of the g- conformation of Ser and Thr on the structure of transmembrane helices.
Topics: Aquaporins; Escherichia coli Proteins; Membrane Proteins; Models, Molecular; Molecular Dynamics Simulation; Protein Structure, Secondary; Receptors, Adrenergic, beta-2; Serine; Structure-Activity Relationship; Threonine | 2010 |
Cell biology. Evolving cell signals.
Topics: Animals; Binding Sites; Biological Evolution; CDC2 Protein Kinase; Evolution, Molecular; Fungi; Phosphorylation; Protein Binding; Protein Folding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proteins; Serine; Signal Transduction; Threonine; Tyrosine | 2009 |
Contribution of Ser463 residue to the enzymatic and autoprocessing activities of Escherichia coli gamma-glutamyltranspeptidase.
Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Circular Dichroism; Escherichia coli; gamma-Glutamyltransferase; Glutamine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Tryptophan | 2009 |
Regulation of the transcription factor YY1 in mitosis through phosphorylation of its DNA-binding domain.
Topics: Amino Acid Sequence; Binding Sites; DNA; Gene Expression Regulation; HeLa Cells; Humans; Mitosis; Mutagenesis, Site-Directed; Nocodazole; Phosphorylation; Serine; Threonine; Tubulin Modulators; YY1 Transcription Factor | 2009 |
Regulation of endothelial nitric oxide synthase (eNOS) in myocardium subjected to cardioplegic arrest.
Topics: Animals; Cardiopulmonary Bypass; Enzyme Activation; Female; Heart Arrest, Induced; Heart Ventricles; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Animal; Myocardial Contraction; Myocardium; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Swine; Threonine; Time Factors; Ventricular Function, Left | 2009 |
AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K.
Topics: Animals; Base Sequence; Blotting, Western; Cell Line, Tumor; Cells, Cultured; DNA Mutational Analysis; Enzyme Activation; Gene Frequency; Humans; Mice; Mutation, Missense; NIH 3T3 Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Threonine; Transfection; Urinary Bladder Neoplasms | 2010 |
Cancer Osaka thyroid (Cot) phosphorylates Polo-like kinase (PLK1) at Ser137 but not at Thr210.
Topics: Amino Acid Sequence; Cell Cycle Proteins; Cell Line; Humans; MAP Kinase Kinase Kinases; Models, Molecular; Molecular Sequence Data; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; RNA, Small Interfering; Serine; Substrate Specificity; Threonine | 2009 |
Regulation of protein kinase A activity by p90 ribosomal S6 kinase 1.
Topics: Amino Acids; Animals; Binding Sites; Blotting, Western; Catalytic Domain; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; HeLa Cells; Humans; Immunoprecipitation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Phosphorylation; Protein Binding; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Serine; Threonine; Transfection | 2009 |
Phosphorylation of protease-activated receptor-2 differentially regulates desensitization and internalization.
Topics: Animals; Arrestins; beta-Arrestins; Cell Line; Endocytosis; Fibroblasts; GTP-Binding Proteins; Humans; Models, Biological; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Rats; Receptor, PAR-2; Serine; Threonine | 2009 |
Structure and function of glycosylated tandem repeats from Candida albicans Als adhesins.
Topics: Amino Acid Sequence; Candida albicans; Cell Adhesion Molecules; Circular Dichroism; Disaccharides; Enzyme-Linked Immunosorbent Assay; Fibronectins; Fungal Proteins; Glycosylation; Lectins; Mannosides; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Peptide Fragments; Polystyrenes; Protein Binding; Protein Denaturation; Protein Interaction Domains and Motifs; Protein Renaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Threonine | 2010 |
Identification of the autophosphorylation sites of LRRK2.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies; Biocatalysis; Cell Line; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Holoenzymes; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Microfilament Proteins; Parkinson Disease; Peptide Fragments; Phosphorylation; Phosphothreonine; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spodoptera; Threonine; Transfection | 2009 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells.
Topics: Angiotensin II; Animals; Cell Line; Enzyme Inhibitors; ErbB Receptors; Hepatocytes; Insulin; Insulin Resistance; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Receptor, Insulin; Serine; Signal Transduction; Threonine; Transcriptional Activation; Tyrphostins; Vasoconstrictor Agents | 2010 |
Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster.
Topics: Acetylation; Alanine; Animals; Animals, Genetically Modified; Binding Sites; Blotting, Western; Carboxy-Lyases; Cell Line; Databases, Protein; Drosophila melanogaster; Drosophila Proteins; HeLa Cells; Humans; Immunoprecipitation; Mass Spectrometry; Mutation; Protein Biosynthesis; Protein Processing, Post-Translational; Serine; Threonine; Transgenes | 2009 |
A transition path ensemble study reveals a linchpin role for Mg(2+) during rate-limiting ADP release from protein kinase A.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Algorithms; Binding Sites; Cations, Divalent; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Glycine; Kinetics; Magnesium; Models, Molecular; Serine; Thermodynamics; Threonine | 2009 |
PDK1 regulates chemotaxis in human neutrophils.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Aggressive Periodontitis; Blotting, Western; Cells, Cultured; Chemotaxis, Leukocyte; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Silencing; Humans; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Serine; Signal Transduction; Staurosporine; Superoxides; Temperature; Threonine; Time Factors | 2009 |
Identification of substrates for Ser/Thr kinases using residue-based statistical pair potentials.
Topics: Binding Sites; Computational Biology; Databases, Protein; Models, Molecular; Protein Serine-Threonine Kinases; Sequence Analysis, Protein; Serine; Substrate Specificity; Threonine | 2010 |
Synthesis of Lipoamino acids and their activity against cerebral ischemic injury.
Topics: Anaerobiosis; Animals; Brain; Brain Ischemia; Hydrogen Peroxide; Neuroprotective Agents; Rats; Serine; Threonine; Tyrosine | 2009 |
Conformational effects of the non-natural alpha-methylserine on small peptides and glycopeptides.
Topics: Alanine; Amides; Amino Acid Sequence; Glycopeptides; Glycosylation; Molecular Dynamics Simulation; Molecular Sequence Data; Peptides; Protein Conformation; Serine; Solvents; Threonine; Water | 2009 |
Is Asp-His-Ser/Thr-Trp tetrad hydrogen-bond network important to WD40-repeat proteins: a statistical and theoretical study.
Topics: Amino Acid Sequence; Aspartic Acid; Crystallography, X-Ray; Databases, Protein; Histidine; Humans; Hydrogen Bonding; Molecular Sequence Data; Molecular Structure; Protein Conformation; Proteins; Serine; Threonine; Tryptophan | 2010 |
Characterization of two isotypes of l-threonine dehydratase from Entamoeba histolytica.
Topics: Adenosine Monophosphate; Allosteric Regulation; Amino Acid Sequence; Ammonia; Animals; Carboxylic Acids; Cysteine; Cytidine Monophosphate; Entamoeba histolytica; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoelectric Point; Isoenzymes; Kinetics; Molecular Sequence Data; Molecular Weight; Protozoan Proteins; Pyridoxal; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Threonine; Threonine Dehydratase | 2010 |
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase.
Topics: 3T3 Cells; Animals; Cullin Proteins; Drosophila Proteins; Intracellular Signaling Peptides and Proteins; Kruppel-Like Transcription Factors; Mice; Nuclear Proteins; Protein Stability; Repressor Proteins; Serine; Threonine; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Zinc Finger Protein GLI1 | 2009 |
The products of pronase digestion of purified blood group-specific glycoproteins.
Topics: Blood Group Antigens; Chromatography, Gel; Galactosamine; Glucosamine; Glycoproteins; Glycosides; Humans; Hydrolysis; Peptide Hydrolases; Proline; Pronase; Sepharose; Serine; Sulfur; Threonine; Time Factors; Ultracentrifugation | 1973 |
Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebellum; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperammonemia; In Vitro Techniques; Male; Microdialysis; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Phosphorylation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Statistics, Nonparametric; Subcellular Fractions; Threonine | 2010 |
Effects of sulfur amino acids on tyrosyl or serine/threonine phosphorylation and translocation of cytosolic compounds to cell membrane in stimulus-treated human neutrophils.
Topics: Amino Acids, Sulfur; Animals; Biological Transport; Cell Membrane; Cells, Cultured; Humans; Lipid Peroxidation; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; rac GTP-Binding Proteins; Respiratory Burst; Serine; Superoxides; Threonine; Tyrosine | 2009 |
FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex.
Topics: Actins; Animals; Animals, Newborn; Apoptosis; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen Type I; Enzyme Activation; Fibroblasts; Focal Adhesion Kinase 1; Intracellular Signaling Peptides and Proteins; Leucine; Matrix Metalloproteinase 2; Mechanotransduction, Cellular; Myocardium; Oligopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases; RNA Interference; Serine; Sirolimus; Stress, Mechanical; Threonine; Time Factors; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Tyrosine | 2010 |
Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Adult; Amino Acid Substitution; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Bariatric Surgery; Biguanides; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Humans; Insulin Resistance; Lipolysis; Overweight; Patient Selection; Ribonucleotides; Serine; Thiazolidinediones; Threonine | 2010 |
Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation.
Topics: Amino Acid Sequence; Animals; ARNTL Transcription Factors; Cells, Cultured; Circadian Rhythm; Dopamine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Molecular Sequence Data; Phosphorylation; Protein Processing, Post-Translational; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Ubiquitination | 2010 |
Identification and analysis of residues contained on beta --> alpha loops of the dual-substrate (beta alpha)8 phosphoribosyl isomerase A specific for its phosphoribosyl anthranilate isomerase activity.
Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Arginine; Asparagine; Catalytic Domain; Crystallography, X-Ray; Evolution, Molecular; Kinetics; Protein Conformation; Protein Structure, Secondary; Sequence Analysis, Protein; Serine; Streptomyces coelicolor; Threonine | 2010 |
CASK phosphorylation by PKA regulates the protein-protein interactions of CASK and expression of the NMDAR2b gene.
Topics: Animals; Brain; Cell Line; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disks Large Homolog 4 Protein; Enzyme Inhibitors; Gene Expression Regulation; Guanylate Kinases; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Isoquinolines; Membrane Proteins; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Neuroblastoma; Neurons; Phosphoproteins; Phosphorylation; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sulfonamides; Syndecan-2; T-Box Domain Proteins; Tetrodotoxin; Threonine; Transfection; Up-Regulation; Zonula Occludens-1 Protein | 2010 |
Phosphorylation of Thr-516 and Ser-520 in the kinase activation loop of MEKK3 is required for lysophosphatidic acid-mediated optimal IkappaB kinase beta (IKKbeta)/nuclear factor-kappaB (NF-kappaB) activation.
Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Specificity; Cell Division; Cells, Cultured; Humans; I-kappa B Kinase; Interleukin-6; Kidney; Luciferases; Lysophospholipids; MAP Kinase Kinase Kinase 3; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Phosphorylation; Protein Kinase C; Rabbits; Serine; Signal Transduction; Threonine | 2010 |
Differential effects of Tau on the integrity and function of neurons essential for learning in Drosophila.
Topics: Animals; Animals, Genetically Modified; B7-1 Antigen; Behavior, Animal; Discrimination Learning; Drosophila; Drosophila Proteins; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Humans; Larva; Memory; Mushroom Bodies; Mutation; Nerve Tissue Proteins; Neurons; Olfactory Pathways; Phosphorylation; Serine; tau Proteins; Threonine | 2010 |
Serine/threonine kinase akt activation regulates the activity of retinal serine/threonine phosphatases, PHLPP and PHLPPL.
Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hypoglycemic Agents; Insulin; Molecular Weight; Nuclear Proteins; Oncogene Protein v-akt; Organ Culture Techniques; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Retina; Retinal Rod Photoreceptor Cells; Serine; Signal Transduction; Stress, Psychological; Threonine; Transfection | 2010 |
Transient overexpression of alpha-Ca2+/calmodulin-dependent protein kinase II in the nucleus accumbens shell enhances behavioral responding to amphetamine.
Topics: Amphetamines; Analysis of Variance; Animals; Aspartic Acid; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Central Nervous System Stimulants; Conditioning, Operant; CREB-Binding Protein; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Regulation; Gene Transfer Techniques; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, AMPA; Self Administration; Serine; Threonine; Time Factors | 2010 |
Glycine oxidation and conversion into amino acids in Saccharomyces cerevisiae and Candida albicans.
Topics: Candida albicans; Glycine; Oxidation-Reduction; Saccharomyces cerevisiae; Serine; Threonine | 2010 |
The phosphoproteome of the minimal bacterium Mycoplasma pneumoniae: analysis of the complete known Ser/Thr kinome suggests the existence of novel kinases.
Topics: Amino Acid Sequence; Bacterial Adhesion; Bacterial Proteins; Conserved Sequence; Enzyme Activation; Glycolysis; Mass Spectrometry; Molecular Sequence Data; Mutation; Mycoplasma pneumoniae; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proteome; Serine; Threonine | 2010 |
An improved procedure for the synthesis of dehydroamino acids and dehydropeptides from the carbonate derivatives of serine and threonine using tetrabutylammonium fluoride.
Topics: Alanine; Carbonates; gamma-Aminobutyric Acid; Peptides; Quaternary Ammonium Compounds; Serine; Threonine | 2010 |
Structure and function of the apoA-IV T347S and Q360H common variants.
Topics: Amino Acid Substitution; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins A; Cell Line; Cholesterol; Endothelium, Vascular; Glutamine; Histidine; Homeostasis; Humans; Inflammation; Interleukin-6; Lipid Metabolism; Lipoproteins, HDL; Mice; Protein Structure, Secondary; Serine; Threonine; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2010 |
Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.
Topics: Adenosine Triphosphate; Animals; Ataxia Telangiectasia Mutated Proteins; Base Sequence; Cell Cycle Proteins; Cell Line; DNA; DNA Damage; DNA-Binding Proteins; Glutamine; Humans; Molecular Structure; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; RNA Interference; Serine; Threonine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2010 |
Beneficial effect of the oligomerized polyphenol oligonol on high glucose-induced changes in eNOS phosphorylation and dephosphorylation in endothelial cells.
Topics: Animals; Bradykinin; Cardiovascular Agents; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Glucose; Nitric Oxide; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Serine; Signal Transduction; Superoxide Dismutase; Swine; Threonine; Time Factors | 2010 |
Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.
Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Cell Line; Enzyme Inhibitors; Humans; Insulin; Insulin Resistance; Mice; Muscle, Skeletal; NIH 3T3 Cells; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Serine; Sirolimus; Threonine; Transcription Factors; Wortmannin | 2010 |
Raptor is phosphorylated by cdc2 during mitosis.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Binding Sites; CDC2 Protein Kinase; Cell Line; Cell Line, Tumor; Cyclin B; Cyclin-Dependent Kinases; HeLa Cells; Humans; Immunoblotting; Immunoprecipitation; Mass Spectrometry; Mitosis; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Regulatory-Associated Protein of mTOR; Sequence Homology, Amino Acid; Serine; Threonine; Transcription Factors; Transfection | 2010 |
The amino-terminal region of hemokinin-1 regulates the induction of thermal hyperalgesia in rats.
Topics: Amino Acid Sequence; Animals; Arginine; Hyperalgesia; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Serine; Substance P; Tachykinins; Threonine | 2010 |
Caffeine and theophylline block insulin-stimulated glucose uptake and PKB phosphorylation in rat skeletal muscles.
Topics: Animals; Caffeine; Dantrolene; Dose-Response Relationship, Drug; Electric Stimulation; Glucose; Glucose Transporter Type 4; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Insulin; Male; Muscle Contraction; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Theophylline; Threonine; Time Factors | 2010 |
Metal cation dependence of interactions with amino acids: bond energies of Rb+ to Gly, Ser, Thr, and Pro.
Topics: Amino Acids; Cations; Glycine; Proline; Rubidium; Serine; Tandem Mass Spectrometry; Thermodynamics; Threonine; Xenon | 2010 |
Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ.
Topics: Amino Acid Sequence; Animals; Dimerization; Mice; Molecular Sequence Data; Mycobacterium tuberculosis; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Sequence Alignment; Serine; Signal Transduction; Threonine; Tuberculosis; Virulence | 2010 |
Dissecting the M phase-specific phosphorylation of serine-proline or threonine-proline motifs.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites; cdc25 Phosphatases; Epitopes; Female; Immunoblotting; Mitogen-Activated Protein Kinases; Mitosis; Oocytes; Phosphorylation; Proline; Recombinant Fusion Proteins; Serine; Threonine; Xenopus; Xenopus Proteins | 2010 |
Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the muscle microcirculation increases nitric oxide synthesis and microvascular perfusion.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Hindlimb; Infusions, Intravenous; Microcirculation; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroarginine; Phosphorylation; Pyrazoles; Pyrimidines; Rats; Regional Blood Flow; Ribonucleotides; S-Nitroso-N-Acetylpenicillamine; Serine; Threonine; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents | 2010 |
alpha-Amino-beta-hydroxy-gamma-lactam for constraining peptide Ser and Thr residue conformation.
Topics: Lactams; Molecular Conformation; Peptides; Serine; Threonine | 2010 |
Salicylaldehyde ester-induced chemoselective peptide ligations: enabling generation of natural peptidic linkages at the serine/threonine sites.
Topics: Aldehydes; Catalysis; Peptides; Serine; Substrate Specificity; Threonine | 2010 |
Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants.
Topics: Candida albicans; Cell Proliferation; Cycloheximide; Feedback, Physiological; Fungal Proteins; Genes, Suppressor; Homoserine; Mutation; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Proteasome Endopeptidase Complex; Protein Biosynthesis; Saccharomyces cerevisiae; Serine; Suppression, Genetic; Threonine | 2010 |
Phosphorylation of histone H2A.X by DNA-dependent protein kinase is not affected by core histone acetylation, but it alters nucleosome stability and histone H1 binding.
Topics: Animals; DNA; DNA-Activated Protein Kinase; HeLa Cells; Histones; Humans; Mice; Nucleosomes; Phosphorylation; Plasmids; Protein Processing, Post-Translational; Serine; Threonine; Transfection | 2010 |
The T-loop extension of the tomato protein kinase AvrPto-dependent Pto-interacting protein 3 (Adi3) directs nuclear localization for suppression of plant cell death.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Active Transport, Cell Nucleus; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Cell Nucleus; Models, Biological; Nuclear Localization Signals; Phosphorylation; Plant Proteins; Plasmids; Protein Kinases; Protein Serine-Threonine Kinases; Serine; Solanum lycopersicum; Subcellular Fractions; Threonine | 2010 |
In vitro phosphorylation of key metabolic enzymes from Bacillus subtilis: PrkC phosphorylates enzymes from different branches of basic metabolism.
Topics: Bacillus subtilis; Bacterial Proteins; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Serine; Threonine | 2010 |
Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells.
Topics: Cell Cycle Proteins; Cell Line, Tumor; Chemokines, CXC; Humans; Immediate-Early Proteins; Intracellular Signaling Peptides and Proteins; Neovascularization, Pathologic; NF-kappa B; Pancreatic Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Sequence Deletion; Serine; Threonine | 2010 |
Modulation of the Arabidopsis KAT1 channel by an activator of protein kinase C in Xenopus laevis oocytes.
Topics: Amino Acid Substitution; Animals; Arabidopsis Proteins; Electrophysiological Phenomena; Naphthalenes; Oocytes; Phosphorylation; Potassium Channels, Inwardly Rectifying; Protein Interaction Domains and Motifs; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; Threonine; Transfection; Xenopus laevis | 2010 |
Protein phosphatase 2A acts as a mitogen-activated protein kinase kinase kinase 3 (MEKK3) phosphatase to inhibit lysophosphatidic acid-induced IkappaB kinase beta/nuclear factor-kappaB activation.
Topics: Cell Line; HeLa Cells; Humans; I-kappa B Kinase; Lysophospholipids; MAP Kinase Kinase Kinase 3; NF-kappa B; Phosphorylation; Protein Isoforms; Protein Phosphatase 2; Retroviridae; RNA, Small Interfering; Serine; Signal Transduction; Threonine | 2010 |
Aminoacyl transfer rate dictates choice of editing pathway in threonyl-tRNA synthetase.
Topics: Adenosine Triphosphate; Binding Sites; Catalytic Domain; Escherichia coli; Hydrolysis; Kinetics; Models, Biological; Models, Chemical; Models, Genetic; RNA Editing; RNA, Transfer, Amino Acyl; Serine; Solvents; Threonine | 2010 |
Identification of a novel in vivo virus-targeted phosphorylation site in interferon regulatory factor-3 (IRF3).
Topics: Amino Acid Sequence; Binding Sites; Gene Expression Regulation, Viral; Humans; Interferon Regulatory Factor-3; Mass Spectrometry; Molecular Sequence Data; Mutagenesis; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Sendai virus; Sequence Homology, Amino Acid; Serine; Threonine | 2010 |
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.
Topics: Amino Acid Sequence; Animals; Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome; Apoptosis; Caspase 9; CDC2 Protein Kinase; Cdc20 Proteins; Cell Cycle Proteins; Cell Line; Cyclin B1; Humans; Mitosis; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Phosphopeptides; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Serine; Threonine | 2010 |
Uncoating of human immunodeficiency virus type 1 requires prolyl isomerase Pin1.
Topics: Capsid Proteins; Cell Line; Cell Line, Tumor; HIV-1; Humans; Jurkat Cells; Leukemia, T-Cell; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; RNA, Small Interfering; Serine; Threonine | 2010 |
Calponin h1-S175T point mutation enhances resistance to actin cytoskeleton perturbation in human cancer cells.
Topics: Actin Cytoskeleton; Actins; Amino Acid Substitution; Binding Sites; Calcium-Binding Proteins; Calponins; Cell Movement; Cytochalasin D; HeLa Cells; Humans; Microfilament Proteins; Phorbol 12,13-Dibutyrate; Point Mutation; Serine; Threonine; Transfection | 2010 |
Mass spectrometric analysis, automated identification and complete annotation of O-linked glycopeptides.
Topics: Acetylgalactosamine; Asparagine; Automation; Chromatography, Liquid; Galactose; Glycopeptides; Glycosylation; Mass Spectrometry; Serine; Threonine; Tryptophan | 2010 |
Influence of phosphorylation of THR-3, SER-11, and SER-15 on deoxycytidine kinase activity and stability.
Topics: Cell Line; Deoxycytidine Kinase; Enzyme Stability; Humans; Mutagenesis, Site-Directed; Phosphorylation; Serine; Structure-Activity Relationship; Threonine | 2010 |
Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport.
Topics: Animals; Biological Transport; Blotting, Western; Cell Line; Cells, Cultured; Dopamine; Electrophoresis, Polyacrylamide Gel; Humans; Mice; Parathyroid Hormone; Phosphates; Phosphoproteins; Phosphorylation; Protein Binding; Serine; Sodium-Hydrogen Exchangers; Sodium-Phosphate Cotransporter Proteins, Type IIa; Threonine | 2010 |
Involvement of threonine 258 and serine 259 motif in amphetamine-induced norepinephrine transporter endocytosis.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Biotinylation; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Membrane; Central Nervous System Stimulants; Desipramine; Down-Regulation; Endocytosis; Female; Humans; Mutation; Norepinephrine Plasma Membrane Transport Proteins; Placenta; Pregnancy; Protein Kinase C; Protein Kinase Inhibitors; Serine; Signal Transduction; Threonine; Trophoblasts | 2010 |
Differential phosphorylation of myosin light chain (Thr)18 and (Ser)19 and functional implications in platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cell Shape; Humans; Kinetics; Myosin Light Chains; Phosphorylation; Platelet Aggregation; rho-Associated Kinases; Serine; Signal Transduction; Threonine | 2010 |
DevT (Alr4674), resembling a Ser/Thr protein phosphatase, is essential for heterocyst function in the cyanobacterium Anabaena sp. PCC 7120.
Topics: Anabaena; Bacterial Proteins; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Phosphoprotein Phosphatases; Serine; Threonine | 2010 |
PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2.
Topics: Animals; Blotting, Western; cdc25 Phosphatases; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Electrophoresis, Polyacrylamide Gel; Endothelium, Corneal; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphorylation; Rabbits; rac1 GTP-Binding Protein; RNA, Small Interfering; Serine; Stathmin; Threonine; Transfection | 2011 |
The active Zot domain (aa 288-293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation.
Topics: Amino Acid Sequence; Animals; Caco-2 Cells; Cell Line; Cells, Cultured; Cholera Toxin; Endotoxins; Epithelial Cells; Humans; Immunoblotting; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Myosins; Oligopeptides; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C-alpha; Rats; Rats, Wistar; Receptor, PAR-2; RNA Interference; Serine; Threonine; Tight Junctions; Zonula Occludens-1 Protein | 2011 |
Phosphorylation of p37 is important for Golgi disassembly at mitosis.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Golgi Apparatus; HeLa Cells; Humans; Membrane Fusion; Mitosis; Mutation; Nuclear Proteins; Phosphorylation; Serine; Threonine | 2010 |
Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain.
Topics: Amino Acid Sequence; Binding Sites; ErbB Receptors; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-cbl; Serine; src Homology Domains; Threonine | 2010 |
Serine/threonine protein phosphatase assays.
Topics: Colorimetry; Enzyme Assays; Phosphoprotein Phosphatases; Radiometry; Serine; Threonine | 2010 |
Two histone marks establish the inner centromere and chromosome bi-orientation.
Topics: Amino Acid Sequence; Aurora Kinase B; Aurora Kinases; Cell Cycle Proteins; Centromere; Chromatin; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Chromosomes, Fungal; Chromosomes, Human; Cohesins; HeLa Cells; Heterochromatin; Histones; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Kinetochores; Microtubule-Associated Proteins; Mitosis; Molecular Sequence Data; Mutation; Nucleosomes; Phosphorylation; Protein Binding; Protein Interaction Domains and Motifs; Protein Serine-Threonine Kinases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Serine; Survivin; Threonine | 2010 |
Evolution of protein phosphorylation for distinct functional modules in vertebrate genomes.
Topics: Animals; Conserved Sequence; Evolution, Molecular; Gene Regulatory Networks; Genome; Humans; Phosphoproteins; Phosphorylation; Proteomics; Serine; Structure-Activity Relationship; Threonine; Tyrosine; Vertebrates | 2011 |
Tyrosine dephosphorylation is required for Bak activation in apoptosis.
Topics: Amino Acid Sequence; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Cell Line; Extracellular Signal-Regulated MAP Kinases; Humans; Mitochondria; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatases, Non-Receptor; Serine; Threonine; Tyrosine | 2010 |
The M2-type isoenzyme of pyruvate kinase phosphorylates prothymosin α in proliferating lymphocytes.
Topics: Amino Acid Sequence; Animals; Cell Line, Transformed; Cell Proliferation; HEK293 Cells; Humans; In Vitro Techniques; Lymphocytes; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Precursors; Pyruvate Kinase; Rabbits; Recombinant Proteins; Serine; Substrate Specificity; Threonine; Thymosin | 2011 |
Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu.
Topics: Amino Acid Sequence; Animals; Antigens, CD; beta-Transducin Repeat-Containing Proteins; Down-Regulation; GPI-Linked Proteins; HEK293 Cells; HIV-1; Human Immunodeficiency Virus Proteins; Humans; Molecular Sequence Data; Serine; Threonine; Ubiquitin; Viral Regulatory and Accessory Proteins; Virion; Virus Release | 2011 |
Phospho.ELM: a database of phosphorylation sites--update 2011.
Topics: Amino Acid Sequence; Animals; Conserved Sequence; Databases, Protein; Humans; Mice; Phosphoproteins; Phosphorylation; Protein Conformation; Sequence Analysis, Protein; Serine; Threonine; Tyrosine | 2011 |
Phosphorylation of RIG-I by casein kinase II inhibits its antiviral response.
Topics: Amino Acid Substitution; Casein Kinase II; Cell Line; DEAD Box Protein 58; DEAD-box RNA Helicases; Humans; Interferon-alpha; Interferon-beta; Mutagenesis, Site-Directed; Phosphorylation; Receptors, Immunologic; Serine; Threonine; Viruses | 2011 |
Redox regulation of the AMP-activated protein kinase.
Topics: Acetyl-CoA Carboxylase; Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Antioxidants; Berberine; Blotting, Western; Cattle; Cell Line; Cyclic N-Oxides; Electron Transport Complex IV; Endothelial Cells; Enzyme Activation; Humans; Mitochondria; Oxidation-Reduction; Peroxynitrous Acid; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Serine; Spin Labels; Superoxide Dismutase; Superoxides; Threonine; Time Factors | 2010 |
Phosphorylation of phosphatidate phosphatase regulates its membrane association and physiological functions in Saccharomyces cerevisiae: identification of SER(602), THR(723), AND SER(744) as the sites phosphorylated by CDC28 (CDK1)-encoded cyclin-dependen
Topics: CDC28 Protein Kinase, S cerevisiae; Endoplasmic Reticulum; Inositol; Lipid Metabolism; Mutagenesis, Site-Directed; Nuclear Envelope; Phenotype; Phosphatidate Phosphatase; Phosphatidic Acids; Phosphorylation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Triglycerides | 2011 |
Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids.
Topics: Animals; Cell Line; Chlorocebus aethiops; COS Cells; Cysteine; Endoplasmic Reticulum; Humans; Hydrogen-Ion Concentration; Immunoglobulin kappa-Chains; Lysine; Mice; NIH 3T3 Cells; Protein Structure, Tertiary; Protein Unfolding; Saccharomyces cerevisiae Proteins; Serine; Sodium Hydroxide; Substrate Specificity; Threonine; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2010 |
Molecular recognition of β-O-GlcNAc glycopeptides by a lectin-like receptor: binding modulation by the underlying Ser or Thr amino acids.
Topics: Glycopeptides; Lectins; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Serine; Threonine | 2011 |
Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels.
Topics: Age of Onset; Aged; Alzheimer Disease; Amino Acid Substitution; Female; Frontotemporal Lobar Degeneration; Gene Expression; Genetic Predisposition to Disease; Heterozygote; Humans; Intercellular Signaling Peptides and Proteins; Kaplan-Meier Estimate; Linkage Disequilibrium; Male; Membrane Proteins; Middle Aged; Mutation; Nerve Tissue Proteins; Polymorphism, Single Nucleotide; Progranulins; Proportional Hazards Models; Risk Assessment; Risk Factors; Serine; Threonine; Time Factors | 2011 |
MYC phosphorylation, activation, and tumorigenic potential in hepatocellular carcinoma are regulated by HMG-CoA reductase.
Topics: Animals; Atorvastatin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Hep G2 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Kaplan-Meier Estimate; Liver Neoplasms; Mice; Mice, SCID; Mice, Transgenic; Mutation; Phosphorylation; Proto-Oncogene Proteins c-myc; Pyrroles; rac GTP-Binding Proteins; Serine; Threonine; Tumor Burden; Xenograft Model Antitumor Assays | 2011 |
An efficient approach for the characterization of mucin-type glycopeptides: the effect of O-glycosylation on the conformation of synthetic mucin peptides.
Topics: Amino Acid Sequence; Glycopeptides; Glycosylation; Humans; Models, Molecular; Mucin 5AC; Mucin-4; Mucins; N-Acetylgalactosaminyltransferases; Nuclear Magnetic Resonance, Biomolecular; Serine; Threonine | 2011 |
Rampant purifying selection conserves positions with posttranslational modifications in human proteins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Evolution, Molecular; Humans; Models, Genetic; Phylogeny; Protein Processing, Post-Translational; Proteins; Selection, Genetic; Sequence Alignment; Serine; Threonine; Tyrosine | 2011 |
Tyrosine 656 in topoisomerase IIβ is important for the catalytic activity of the enzyme: Identification based on artifactual +80-Da modification at this site.
Topics: Antibodies, Phospho-Specific; Artifacts; Biocatalysis; Blotting, Western; Circular Dichroism; Cyanogen Bromide; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Halogenation; HL-60 Cells; Humans; Isoenzymes; Models, Molecular; Mutation; Phosphorylation; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Threonine; Trypsin; Tyrosine | 2011 |
Development of chemically defined media supporting high cell density growth of Ketogulonicigenium vulgare and Bacillus megaterium.
Topics: Bacillus megaterium; Biomass; Biotin; Culture Media; Glycine; Niacin; Proline; Rhodobacteraceae; Serine; Sorbose; Sugar Acids; Threonine; Zea mays | 2011 |
Autoregulatory characteristics of a Bacillus anthracis serine/threonine kinase.
Topics: Amino Acid Sequence; Bacillus anthracis; DNA Mutational Analysis; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Mutant Proteins; Mutation, Missense; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Sequence Homology, Amino Acid; Serine; Tandem Mass Spectrometry; Threonine | 2011 |
Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways.
Topics: Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Cell Membrane; HEK293 Cells; Humans; Ions; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Sequence Alignment; Serine; Signal Transduction; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Threonine | 2011 |
c-Jun N-terminal kinase (JNK-1) confers protection against brief but not extended ischemia during acute myocardial infarction.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Catalysis; Glucose; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase 8; Myocardial Infarction; Phosphorylation; Serine; Threonine | 2011 |
Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex.
Topics: Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Inhibitors; ErbB Receptors; HEK293 Cells; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Proteasome Endopeptidase Complex; Serine; Threonine | 2011 |
Pharmacologic modulation of serine/threonine phosphorylation highly sensitizes PHEO in a MPC cell and mouse model to conventional chemotherapy.
Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Humans; Mice; Neoplasm Metastasis; Pheochromocytoma; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 2; Serine; Temozolomide; Threonine | 2011 |
Crystal structure of E339K mutated human glucokinase reveals changes in the ATP binding site.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Glucokinase; Glucose; Histidine; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Threonine | 2011 |
Stabilization of triple-helical structures of collagen peptides containing a Hyp-Thr-Gly, Hyp-Val-Gly, or Hyp-Ser-Gly sequence.
Topics: Amino Acid Sequence; Circular Dichroism; Collagen; Crystallization; Crystallography, X-Ray; Glycine; Hydroxyproline; Molecular Conformation; Molecular Sequence Data; Peptides; Proline; Protein Conformation; Protein Structure, Secondary; Sequence Homology, Amino Acid; Serine; Threonine; Valine | 2011 |
Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent manner.
Topics: Down-Regulation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Substrate Specificity; Threonine | 2011 |
ATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2A.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; DNA-Binding Proteins; Down-Regulation; Humans; Phosphorylation; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-mdm2; Serine; Threonine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2011 |
Characterization of AMPylation on threonine, serine, and tyrosine using mass spectrometry.
Topics: Adenosine Monophosphate; Amino Acid Sequence; Biochemical Phenomena; Mass Spectrometry; Peptides; Serine; Threonine; Tyrosine | 2011 |
Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system.
Topics: Arabidopsis; Arabidopsis Proteins; Cell-Free System; Phosphorylation; Protein Kinases; Serine; Threonine | 2011 |
Swim-exercised mice show a decreased level of protein O-GlcNAcylation and expression of O-GlcNAc transferase in heart.
Topics: Acetylglucosamine; Adaptation, Physiological; Animals; Cardiomegaly; Down-Regulation; Gene Expression Regulation, Enzymologic; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Glycosylation; Male; Mice; Muscle Contraction; Muscle Proteins; Myocardium; N-Acetylglucosaminyltransferases; Nitrogenous Group Transferases; Physical Exertion; Protein Processing, Post-Translational; RNA, Messenger; Serine; Swimming; Threonine | 2011 |
Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer.
Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Enzyme Activation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2011 |
Developmental downregulation of Xenopus cyclin E is phosphorylation and nuclear import dependent and is mediated by ubiquitination.
Topics: Active Transport, Cell Nucleus; Animals; Cell Nucleus; Cyclin E; Cyclin-Dependent Kinase 2; Down-Regulation; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; Serine; Threonine; Ubiquitination; Xenopus laevis; Xenopus Proteins | 2011 |
PKB signaling and atrogene expression in skeletal muscle of aged mice.
Topics: Age Factors; Aging; Animals; Apoptosis Regulatory Proteins; Autophagy; Cytoskeletal Proteins; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation; Insulin; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mitochondrial Proteins; Muscle Proteins; Muscular Atrophy; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Quadriceps Muscle; RNA, Messenger; Sarcopenia; Serine; Signal Transduction; SKP Cullin F-Box Protein Ligases; Threonine; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2011 |
Forkhead-associated (FHA) domain containing ABC transporter Rv1747 is positively regulated by Ser/Thr phosphorylation in Mycobacterium tuberculosis.
Topics: Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Bacterial Proteins; Female; Macrophages; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Mycobacterium tuberculosis; Operon; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Signal Transduction; Threonine | 2011 |
Discovery of cellular substrates for protein kinase A using a peptide array screening protocol.
Topics: Amino Acid Motifs; Amino Acid Sequence; Blotting, Western; Cell Proliferation; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Humans; LIM Domain Proteins; Male; Molecular Sequence Data; Phosphorylation; Prostatic Neoplasms; Protein Array Analysis; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Threonine; Tumor Cells, Cultured | 2011 |
Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids.
Topics: Binding Sites; cdc25 Phosphatases; Cell Line, Tumor; Click Chemistry; Computer Simulation; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Monosaccharides; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Serine; Threonine | 2011 |
Unconventional myristoylation of large-conductance Ca²⁺-activated K⁺ channel (Slo1) via serine/threonine residues regulates channel surface expression.
Topics: Cell Line; Cell Membrane; Esters; Humans; Immunohistochemistry; Kinetics; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Mutation; Myristic Acid; Patch-Clamp Techniques; Protein Processing, Post-Translational; Serine; Threonine | 2011 |
Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid beta-peptides in human cerebrospinal fluid.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Chromatography, Liquid; Glycosylation; Humans; Molecular Sequence Data; Proteomics; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2011 |
Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase.
Topics: Animals; Carrier Proteins; HEK293 Cells; HeLa Cells; Humans; Mice; Mutation; Phosphorylation; Plasmids; Proteasome Endopeptidase Complex; Protein Binding; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Serine; Signal Transduction; Threonine; Transfection; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Ubiquitination | 2011 |
The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Confounding Factors, Epidemiologic; Cyclin-Dependent Kinase Inhibitor p27; Dasatinib; Drug Synergism; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, bcl-1; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Research Design; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Serine; src-Family Kinases; Thiazoles; Threonine; Tyrosine; Xenograft Model Antitumor Assays | 2011 |
Negative regulation by Ser/Thr phosphorylation of HadAB and HadBC dehydratases from Mycobacterium tuberculosis type II fatty acid synthase system.
Topics: Amino Acid Sequence; Down-Regulation; Fatty Acid Synthase, Type II; Hydro-Lyases; Molecular Sequence Data; Mycobacterium tuberculosis; Phosphorylation; Serine; Threonine | 2011 |
Energy maps, side chain conformational flexibility, and vibrational features of polar amino acids L-serine and L-threonine in aqueous environment.
Topics: Models, Molecular; Molecular Conformation; Serine; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics; Threonine; Water | 2011 |
Stability of mitochondrial membrane proteins in terrestrial vertebrates predicts aerobic capacity and longevity.
Topics: Animals; Cell Respiration; Humans; Hydrogen Bonding; Longevity; Membrane Proteins; Mitochondrial Membranes; Mitochondrial Proteins; Serine; Threonine; Vertebrates | 2011 |
Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation.
Topics: Adipocytes; Axin Signaling Complex; beta Catenin; Cell Differentiation; Enzyme Activation; Enzyme Assays; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Imidazoles; Immunoprecipitation; Isoxazoles; Mesenchymal Stem Cells; Osteoblasts; Phosphorylation; Plasmids; Protein Interaction Mapping; Proteolysis; Serine; Threonine; Transfection; Wnt Signaling Pathway | 2012 |
Cytoplasmic Ig alpha serine/threonines fine-tune Ig alpha tyrosine phosphorylation and limit bone marrow plasma cell formation.
Topics: Amino Acid Sequence; Animals; Bone Marrow Cells; Cell Differentiation; Cell Separation; Cytoplasm; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunoblotting; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Phosphorylation; Plasma Cells; Receptors, Antigen, B-Cell; Serine; Signal Transduction; Threonine; Tyrosine | 2011 |
Global IRS-1 phosphorylation analysis in insulin resistance.
Topics: Adult; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Middle Aged; Obesity; Phosphorylation; Protein Processing, Post-Translational; Quadriceps Muscle; Serine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Threonine | 2011 |
Phosphorylation of Ataxin-10 by polo-like kinase 1 is required for cytokinesis.
Topics: Ataxin-10; Binding Sites; Cell Cycle Proteins; Cytokinesis; Gene Knockdown Techniques; Giant Cells; HeLa Cells; Humans; Nerve Tissue Proteins; Phosphorylation; Polo-Like Kinase 1; Protein Interaction Domains and Motifs; Protein Serine-Threonine Kinases; Protein Stability; Proto-Oncogene Proteins; Pteridines; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Transfection; Ubiquitination | 2011 |
Myosin binding protein-C slow is a novel substrate for protein kinase A (PKA) and C (PKC) in skeletal muscle.
Topics: Animals; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Phosphopeptides; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Serine; Threonine | 2011 |
Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo.
Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Differentiation; Cell Movement; Cell Proliferation; Class Ia Phosphatidylinositol 3-Kinase; Curcuma; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Furans; Green Fluorescent Proteins; Heterocyclic Compounds, 2-Ring; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Medicine, Chinese Traditional; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Physiologic; Phosphorylation; Plants, Medicinal; Proto-Oncogene Protein c-fli-1; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Tyrosine; Vascular Endothelial Growth Factor A; Wound Healing; Zebrafish | 2012 |
A novel sequence-based method for phosphorylation site prediction with feature selection and analysis.
Topics: Binding Sites; Computational Biology; Data Mining; Databases, Protein; Peptides; Phosphoproteins; Phosphorylation; Predictive Value of Tests; Protein Processing, Post-Translational; Sequence Analysis, Protein; Serine; Support Vector Machine; Threonine; Tyrosine | 2012 |
Mechanisms of melanocortin-2 receptor (MC2R) internalization and recycling in human embryonic kidney (hek) cells: identification of Key Ser/Thr (S/T) amino acids.
Topics: Arrestins; Blotting, Western; Cell Line; Cell Membrane; Cyclic AMP; Dynamins; Endosomes; Enzyme-Linked Immunosorbent Assay; Humans; Immunoprecipitation; Microscopy, Fluorescence; Protein Binding; Receptor, Melanocortin, Type 2; Serine; Threonine | 2011 |
Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms.
Topics: Amino Acid Substitution; Arachidonic Acid; Aspartic Acid; Biopolymers; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mutagenesis, Site-Directed; Phosphorylation; Protein Isoforms; Serine; tau Proteins; Tauopathies; Threonine | 2011 |
Acid-base thermochemistry of gaseous oxygen and sulfur substituted amino acids (Ser, Thr, Cys, Met).
Topics: Amino Acids; Cysteine; Gases; Methionine; Oxygen; Quantum Theory; Serine; Sulfur; Thermodynamics; Threonine | 2011 |
Human corneal endothelial cells employ phosphorylation of p27(Kip1) at both Ser10 and Thr187 sites for FGF-2-mediated cell proliferation via PI 3-kinase.
Topics: Adolescent; Adult; Aged; Butadienes; Cell Proliferation; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Endothelium, Corneal; Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Microscopy, Confocal; Middle Aged; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; RNA, Small Interfering; Serine; Tetrazolium Salts; Thiazoles; Threonine; Tissue Donors; Transfection; Young Adult | 2011 |
Hydrogen exchange study on the hydroxyl groups of serine and threonine residues in proteins and structure refinement using NOE restraints with polar side-chain groups.
Topics: Deuterium Exchange Measurement; Hydroxides; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Serine; Threonine | 2011 |
Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence.
Topics: Amino Acid Sequence; Bacterial Proteins; Listeria monocytogenes; Molecular Sequence Data; Phosphopeptides; Phosphoproteins; Phosphorylation; Proteomics; Serine; Threonine; Tyrosine; Virulence | 2011 |
Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2.
Topics: Acetyl-CoA Carboxylase; Aldehydes; AMP-Activated Protein Kinases; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Berberine; Blood Glucose; Cholesterol; Enzyme Activation; Humans; Intercellular Adhesion Molecule-1; Ion Channels; Mice; Mitochondrial Proteins; Phosphorylation; Plaque, Atherosclerotic; Protein Transport; Serine; Threonine; Transcription, Genetic; Triglycerides; Tyrosine; Uncoupling Protein 2; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2011 |
Phosphorylation alters backbone conformational preferences of serine and threonine peptides.
Topics: Circular Dichroism; Hydrogen-Ion Concentration; Mathematical Concepts; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorylation; Protein Conformation; Serine; Temperature; Thermodynamics; Threonine | 2011 |
A versatile method for analysis of serine/threonine posttranslational modifications by β-elimination in the presence of pyrazolone analogues.
Topics: Glycopeptides; Phosphopeptides; Protein Processing, Post-Translational; Pyrazolones; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2011 |
Phosphoproteome analysis of Streptomyces development reveals extensive protein phosphorylation accompanying bacterial differentiation.
Topics: Amino Acid Motifs; Bacterial Proteins; Computational Biology; Fractional Precipitation; Phosphoproteins; Phosphorylation; Phylogeny; Protein Kinases; Regulatory Elements, Transcriptional; Serine; Software; Spores, Bacterial; Streptomyces coelicolor; Threonine; Tyrosine | 2011 |
Growth hormone modulation of EGF-induced PI3K-Akt pathway in mice liver.
Topics: Adaptor Proteins, Signal Transducing; Animals; Epidermal Growth Factor; Gene Expression; Growth Hormone; Liver; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinase; Phosphoproteins; Phosphorylation; Protein Binding; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Serine; Signal Transduction; Threonine; TOR Serine-Threonine Kinases | 2012 |
The induction of serine/threonine protein phosphorylations by a PDGFR/TrkA chimera in stably transfected PC12 cells.
Topics: Amino Acid Motifs; Animals; Becaplermin; Cloning, Molecular; Humans; Isotope Labeling; Nerve Growth Factor; Neurites; PC12 Cells; Phosphoproteins; Phosphorylation; Protein Interaction Maps; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteome; Proto-Oncogene Proteins c-sis; Rats; Receptor, trkA; Receptors, Platelet-Derived Growth Factor; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Up-Regulation | 2012 |
Amino acid building blocks for efficient Fmoc solid-phase synthesis of peptides adenylylated at serine or threonine.
Topics: Adenine; Amino Acids; Molecular Structure; Peptides; Serine; Solid-Phase Synthesis Techniques; Threonine | 2011 |
Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors.
Topics: Antigens, Neoplasm; Bicarbonates; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Cell Hypoxia; Cell Line; Cell Movement; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Space; HEK293 Cells; HeLa Cells; HT29 Cells; Humans; Hydrogen-Ion Concentration; Immunoblotting; Mutation; Neoplasms; Phosphorylation; Protein Binding; Serine; Sodium-Bicarbonate Symporters; Threonine | 2011 |
Association between Thr21Met and Ser89Asn polymorphisms of the urotensin II gene and systemic sclerosis.
Topics: Adult; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Scleroderma, Systemic; Serine; Threonine; Turkey; Urotensins | 2012 |
Pathways for water loss from doubly protonated peptides containing serine or threonine.
Topics: Aziridines; Ions; Oligopeptides; Protons; Serine; Tandem Mass Spectrometry; Threonine; Water | 2012 |
Multiple regulatory roles of the carboxy terminus of Ste2p a yeast GPCR.
Topics: Amino Acid Sequence; Endocytosis; Gene Expression Regulation, Fungal; Genes, Reporter; Genotype; Lac Operon; Ligands; Mating Factor; Membrane Proteins; Molecular Sequence Data; Peptides; Phenotype; Phosphorylation; Point Mutation; Protein Structure, Tertiary; Receptors, Mating Factor; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine; Time Factors; Up-Regulation | 2012 |
Analysis of the role of Ser1/Ser2/Thr9 phosphorylation on myosin II assembly and function in live cells.
Topics: Catalytic Domain; Cell Division; Cells, Cultured; HeLa Cells; Humans; Myosin Light Chains; Myosin Type II; Phosphorylation; Serine; Threonine | 2011 |
Ser/ Thr residues at α3/β5 loop of Gαs are important in morphine-induced adenylyl cyclase sensitization but not mitogen-activated protein kinase phosphorylation.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Analgesics, Opioid; Animals; Blotting, Western; Cell Line, Tumor; Cyclic AMP; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gs; Immunoprecipitation; Isoproterenol; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morphine; Mutation; Phosphorylation; Protein Binding; Receptors, Adrenergic, beta-2; Receptors, Opioid, mu; Serine; Threonine; Transfection | 2012 |
Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures.
Topics: Animals; Antiemetics; Biophysical Phenomena; Biotinylation; Body Weight; Carbamazepine; Cells, Cultured; Chromosome Mapping; Disease Models, Animal; DNA Mutational Analysis; Electric Stimulation; Electroencephalography; Electromyography; Epilepsy; Ethylnitrosourea; Gene Transfer Techniques; Humans; Isaacs Syndrome; Kv1.1 Potassium Channel; Male; Membrane Potentials; Mice; Models, Molecular; Mutagenesis; Mutagens; Mutation, Missense; Myokymia; Oocytes; Patch-Clamp Techniques; Protein Transport; Psychomotor Performance; Rats; Rats, Inbred F344; Rats, Mutant Strains; Sequence Analysis; Serine; Survival Analysis; Swimming; Threonine; Time Factors; Xenopus | 2012 |
Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase.
Topics: Calmodulin; Catalytic Domain; Elongation Factor 2 Kinase; HEK293 Cells; Humans; Phosphorylation; Serine; Threonine | 2012 |
Coffee polyphenol caffeic acid but not chlorogenic acid increases 5'AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Biological Transport; Caffeic Acids; Chlorogenic Acid; Coffee; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Activation; Glucose; Hypoglycemic Agents; In Vitro Techniques; Insulin; Isoenzymes; Male; Muscle, Skeletal; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Threonine | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Influence of lineage-specific amino acid dimorphisms in GyrA on Mycobacterium tuberculosis resistance to fluoroquinolones.
Topics: Amino Acid Substitution; DNA Gyrase; DNA, Bacterial; DNA, Superhelical; Drug Resistance, Bacterial; Enzyme Activation; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmids; Recombinant Proteins; Serine; Threonine | 2012 |
Hyperglycaemia normalises insulin action on glucose metabolism but not the impaired activation of AKT and glycogen synthase in the skeletal muscle of patients with type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Female; Glucose; Glucose Clamp Technique; Glycogen Synthase; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Muscle, Skeletal; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2012 |
Calcium/calmodulin stimulates the autophosphorylation of elongation factor 2 kinase on Thr-348 and Ser-500 to regulate its activity and calcium dependence.
Topics: Amino Acid Sequence; Binding Sites; Calcium; Calmodulin; Elongation Factor 2 Kinase; Humans; Mass Spectrometry; Molecular Sequence Data; Phosphorylation; Serine; Threonine | 2012 |
Model studies on iTRAQ modification of peptides: sequence-dependent reaction specificity.
Topics: Acylation; Amino Acid Sequence; Escherichia coli Proteins; Hydroxylamine; Oligopeptides; Peptide Fragments; Peptide Mapping; Reference Standards; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staining and Labeling; Tandem Mass Spectrometry; Threonine; Tyrosine | 2012 |
Biochemical characterization of a recombinant Swainsona canescens calcium-dependent protein kinase (ScCPK1).
Topics: Calcium; Calmodulin; Enzyme Inhibitors; Fabaceae; Histones; Hydrogen-Ion Concentration; Imidazoles; Phosphorylation; Plant Proteins; Protein Kinases; Recombinant Proteins; Serine; Signal Transduction; Sulfonamides; Temperature; Threonine | 2012 |
Substrate-selective and calcium-independent activation of CaMKII by α-actinin.
Topics: Actinin; Actins; Amino Acid Sequence; Animals; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Enzyme Activation; HEK293 Cells; Humans; Immunoblotting; Mice; Microscopy, Fluorescence; Models, Molecular; Molecular Sequence Data; Mutation; Phosphorylation; Prosencephalon; Protein Binding; Protein Structure, Tertiary; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Threonine | 2012 |
Metal cation dependence of interactions with amino acids: bond energies of Cs+ to Gly, Pro, Ser, Thr, and Cys.
Topics: Cations; Cesium; Cysteine; Glycine; Proline; Quantum Theory; Serine; Threonine | 2012 |
Phosphorylation regulates human OCT4.
Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Cells, Cultured; Embryonic Stem Cells; HEK293 Cells; Humans; Immunoprecipitation; Mitogen-Activated Protein Kinase 1; Models, Molecular; Molecular Sequence Data; Mutation; Octamer Transcription Factor-3; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; SOXB1 Transcription Factors; Threonine; Transcription Factors; Transcriptional Activation | 2012 |
Synthesis of cyclopropyl glycosides and their use as novel glycosyl donors.
Topics: Alcohols; Amino Acids; Cyclopropanes; Fluorenes; Glycosides; Glycosylation; Mesylates; Monosaccharides; Serine; Stereoisomerism; Threonine | 2012 |
Site-specific phosphorylation protects glycogen synthase kinase-3β from calpain-mediated truncation of its N and C termini.
Topics: Animals; Apoptosis; Calpain; Cerebellum; Glutamine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Isoleucine; Mutagenesis; Nerve Degeneration; Neurons; Phosphorylation; Protein Structure, Tertiary; Rabbits; Rats; Serine; Threonine | 2012 |
Glycogen synthase kinase 3β (GSK3β) modulates antiviral activity of zinc-finger antiviral protein (ZAP).
Topics: Animals; Carrier Proteins; Gene Library; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Indoles; Lentivirus; Lentivirus Infections; Maleimides; Phosphorylation; Rats; RNA-Binding Proteins; RNA, Small Interfering; RNA, Viral; Serine; Threonine | 2012 |
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
Topics: Cell Cycle Proteins; Cell Line, Tumor; Chromosome Segregation; Green Fluorescent Proteins; Humans; Immunoblotting; Kinesins; Kinetochores; Mass Spectrometry; Microscopy, Fluorescence; Microtubules; Mitosis; Mutation; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Serine; Threonine | 2012 |
Constitutive cholesterol-dependent endocytosis of melanocortin-4 receptor (MC4R) is essential to maintain receptor responsiveness to α-melanocyte-stimulating hormone (α-MSH).
Topics: alpha-MSH; Cell Membrane; Cholesterol; Clathrin; Dose-Response Relationship, Drug; Endocytosis; Endosomes; HEK293 Cells; Homeostasis; Humans; Mutation; Receptor, Melanocortin, Type 4; Receptors, G-Protein-Coupled; RNA, Small Interfering; Serine; Signal Transduction; Threonine | 2012 |
Gene regulation via excitation and BDNF is mediated by induction and phosphorylation of the Etv1 transcription factor in cerebellar granule cells.
Topics: Animals; Base Sequence; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Cells, Cultured; Cerebellum; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Immunoblotting; Luciferases; Mice; Mice, Inbred ICR; Mutation; Phosphorylation; Promoter Regions, Genetic; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Serine; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Threonine; Transcription Factors | 2012 |
Reversible Ser/Thr SHIP phosphorylation: a new paradigm in phosphoinositide signalling?: Targeting of SHIP1/2 phosphatases may be controlled by phosphorylation on Ser and Thr residues.
Topics: Animals; Cell Differentiation; Cell Membrane; Cell Nucleus; Enzyme Activation; Humans; Inositol Polyphosphate 5-Phosphatases; Mice; Mice, Knockout; Phosphatidylinositol Phosphates; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Interaction Mapping; PTEN Phosphohydrolase; Serine; Signal Transduction; Substrate Specificity; Threonine; Tyrosine | 2012 |
Diminished muscle growth in the obese Zucker rat following overload is associated with hyperphosphorylation of AMPK and dsRNA-dependent protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; eIF-2 Kinase; Extracellular Signal-Regulated MAP Kinases; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Phosphorylation; Rats; Rats, Zucker; Serine; Signal Transduction; Threonine; Tyrosine; Ubiquitination | 2012 |
Discovery of O-GlcNAc-modified proteins in published large-scale proteome data.
Topics: Acetylglucosamine; Amino Acid Sequence; Cell Line; Cell Nucleus; Cytoplasm; Databases, Protein; Humans; Molecular Sequence Data; Peptides; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Proteome; Serine; Software; Tandem Mass Spectrometry; Threonine | 2012 |
Screening for POLG W748S and A467T mutations in ataxia patients from Spain.
Topics: Adult; Age of Onset; Aged; Alanine; Ataxia; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Serine; Spain; Threonine; Tryptophan; Young Adult | 2012 |
Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C γ2 (PLCγ2) using TRPM7-kinase.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Chickens; Humans; Magnesium; Molecular Sequence Data; Phospholipase C gamma; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Antigen, B-Cell; Serine; Signal Transduction; Threonine; TRPM Cation Channels | 2012 |
Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging.
Topics: Aging; Animals; Calcium; Carrier Proteins; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphorylation; Protein Phosphatase 1; Proteins; Serine; Threonine; Ventricular Remodeling | 2012 |
Roles of the phosphorylation of specific serines and threonines in the NS1 protein of human influenza A viruses.
Topics: Animals; Catalysis; Cell Line; Cell Line, Tumor; Dogs; HEK293 Cells; Humans; Influenza A virus; Influenza, Human; Pandemics; Phosphorylation; Protein Kinase C-alpha; RNA, Double-Stranded; Serine; Threonine; Time Factors; Viral Nonstructural Proteins | 2012 |
A new paradigm in phosphoinositide signaling? (Comment on DOI 10.1002/bies.201100195).
Topics: Animals; Humans; Inositol Polyphosphate 5-Phosphatases; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Serine; Signal Transduction; Threonine | 2012 |
Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events.
Topics: Acetylation; Animals; Aurora Kinases; Base Sequence; Binding Sites; Checkpoint Kinase 1; DNA Primers; Histones; Humans; Lysine; Models, Molecular; Nucleosomes; Phosphorylation; Protein Kinase C-alpha; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Threonine; Xenopus laevis; Xenopus Proteins | 2012 |
Selective lighting up of segments around Gly, Ala and Ser/Thr in proteins.
Topics: Alanine; Glycine; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Serine; Threonine; Ubiquitin | 2012 |
Protein phosphatase-1M and Rho-kinase affect exocytosis from cortical synaptosomes and influence neurotransmission at a glutamatergic giant synapse of the rat auditory system.
Topics: Animals; Animals, Newborn; Calcium; Cardiac Myosins; Cerebral Cortex; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Exocytosis; Female; Glutamic Acid; Immunoprecipitation; In Vitro Techniques; Male; Mass Spectrometry; Microscopy, Electron, Transmission; Myosin Light Chains; Patch-Clamp Techniques; Phosphorylation; Protein Binding; Protein Phosphatase 1; Qa-SNARE Proteins; Rats; Rats, Wistar; rho-Associated Kinases; Serine; Synapses; Synapsins; Synaptic Transmission; Synaptosomes; Threonine | 2012 |
Divergent behavior of glycosylated threonine and serine derivatives in solid phase peptide synthesis.
Topics: Glycosylation; Molecular Structure; Serine; Solid-Phase Synthesis Techniques; Structure-Activity Relationship; Threonine | 2012 |
Ser/Thr motifs in transmembrane proteins: conservation patterns and effects on local protein structure and dynamics.
Topics: Amino Acid Motifs; Amino Acid Sequence; Computational Biology; Conserved Sequence; Hydrogen Bonding; Membrane Proteins; Membrane Transport Proteins; Molecular Dynamics Simulation; Peptides; Protein Conformation; Receptors, Cell Surface; Serine; Threonine | 2012 |
Calcineurin regulates endothelial barrier function by interaction with and dephosphorylation of myosin phosphatase.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Capillary Permeability; Cattle; Cells, Cultured; Cyclosporine; Electric Impedance; Endothelial Cells; Enzyme Activation; Humans; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Phosphorylation; Protein Binding; rho-Associated Kinases; Serine; Surface Plasmon Resonance; Threonine; Thrombin; Time Factors; Transfection | 2012 |
Interaction of human immunodeficiency virus type 1 Vif with APOBEC3G is not dependent on serine/threonine phosphorylation status.
Topics: Amino Acid Sequence; APOBEC-3G Deaminase; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP-Dependent Protein Kinases; Cytidine Deaminase; Gene Expression Regulation; HEK293 Cells; HIV-1; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Point Mutation; Serine; Threonine; vif Gene Products, Human Immunodeficiency Virus | 2012 |
Suppressor analyses identify threonine as a modulator of ridA mutant phenotypes in Salmonella enterica.
Topics: Alleles; Aspartic Acid; Bacterial Proteins; Mutation; Phenotype; Salmonella enterica; Serine; Suppression, Genetic; Threonine | 2012 |
Piperine, a dietary phytochemical, inhibits angiogenesis.
Topics: Alkaloids; Angiogenesis Inhibitors; Animals; Aorta; Benzodioxoles; Breast Neoplasms; Cell Movement; Cell Proliferation; Chick Embryo; Chromones; Drug Screening Assays, Antitumor; Female; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Morpholines; Neovascularization, Pathologic; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-akt; Rats, Wistar; S Phase; Serine; Threonine; TRPV Cation Channels | 2013 |
Sustained postexercise increases in AS160 Thr642 and Ser588 phosphorylation in skeletal muscle without sustained increases in kinase phosphorylation.
Topics: Animals; Binding Sites; GTPase-Activating Proteins; Male; Muscle Contraction; Phosphorylation; Phosphotransferases; Physical Endurance; Physical Exertion; Protein Binding; Rats; Rats, Wistar; Serine; Threonine | 2012 |
Convergent solid-phase synthesis of N-glycopeptides facilitated by pseudoprolines at consensus-sequence Ser/Thr residues.
Topics: Amino Acid Sequence; Aspartic Acid; Consensus Sequence; Glycopeptides; Molecular Sequence Data; Proline; Serine; Solid-Phase Synthesis Techniques; Threonine | 2012 |
Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases.
Topics: Acyclovir; Adenosine; Bacillus subtilis; Catalysis; Catalytic Domain; Crystallography, X-Ray; Ganciclovir; Genetic Therapy; Humans; Ligands; Models, Molecular; Molecular Conformation; Neoplasms; Phosphates; Prodrugs; Protein Structure, Quaternary; Purine-Nucleoside Phosphorylase; Serine; Threonine; Tubercidin | 2012 |
Role of conformational sampling of Ser16 and Thr17-phosphorylated phospholamban in interactions with SERCA.
Topics: Animals; Calcium-Binding Proteins; Cell Membrane; Computer Simulation; Cytoplasm; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Threonine | 2013 |
Fc receptor-γ subunits with both polar or non-polar amino acids at position of T22 are capable of restoring surface expression of the high-affinity IgE receptor and degranulation in γ subunit-deficient rat basophilic leukemia cells.
Topics: Alanine; Amino Acid Substitution; Animals; Basophils; Cell Degranulation; Cell Line, Tumor; Hydrogen Bonding; Leukemia, Basophilic, Acute; Mutant Proteins; Protein Interaction Domains and Motifs; Protein Subunits; Rats; Receptors, IgE; Recombinant Proteins; Serine; Signal Transduction; Threonine; Transfection | 2013 |
Sulforaphane induced adipolysis via hormone sensitive lipase activation, regulated by AMPK signaling pathway.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Isothiocyanates; Lipolysis; Mice; Phosphorylation; Serine; Signal Transduction; Sterol Esterase; Sulfoxides; Thiocyanates; Threonine | 2012 |
High abundance of Serine/Threonine-rich regions predicted to be hyper-O-glycosylated in the secretory proteins coded by eight fungal genomes.
Topics: Computational Biology; Fungal Proteins; Fungi; Genome, Fungal; Glycosylation; Protein Processing, Post-Translational; Serine; Threonine | 2012 |
Cell signaling, post-translational protein modifications and NMR spectroscopy.
Topics: Acetylation; Acylation; Alkylation; Amino Acids; Arginine; Cell Communication; Eukaryotic Cells; Glycosylation; Histidine; Lysine; Magnetic Resonance Spectroscopy; Methylation; Phosphorylation; Protein Processing, Post-Translational; Proteins; Serine; Threonine; Tyrosine | 2012 |
Phosphorylation of mouse melanopsin by protein kinase A.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dopamine; Gene Expression Regulation; HEK293 Cells; Humans; Light; Light Signal Transduction; Mice; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Phylogeny; Protein Structure, Secondary; Protein Structure, Tertiary; Retinal Ganglion Cells; Rod Opsins; Serine; Threonine; Transfection | 2012 |
Recent trends in Cys- and Ser/Thr-based synthetic strategies for the elaboration of peptide constructs.
Topics: Cysteine; Esterification; Imines; Ionic Liquids; Peptides; Serine; Solvents; Sulfur; Threonine; Water | 2012 |
CDPKs are dual-specificity protein kinases and tyrosine autophosphorylation attenuates kinase activity.
Topics: Arabidopsis Proteins; Calcium; Calcium-Binding Proteins; Immunoblotting; Mass Spectrometry; Mutagenesis, Site-Directed; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2012 |
ARF6 and GASP-1 are post-endocytic sorting proteins selectively involved in the intracellular trafficking of dopamine D₂ receptors mediated by GRK and PKC in transfected cells.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Cell Line; Dopamine Agonists; Dopaminergic Neurons; Endosomes; Enzyme Activators; G-Protein-Coupled Receptor Kinase 2; HEK293 Cells; Humans; Intercellular Signaling Peptides and Proteins; Mutant Proteins; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Transport; Proteins; Receptors, Dopamine D2; Recombinant Proteins; RNA Interference; Serine; Tachyphylaxis; Threonine | 2013 |
H2O2-induced endothelial NO production contributes to vascular cell apoptosis and increased permeability in rat venules.
Topics: Animals; Apoptosis; Calcium; Calmodulin; Capillary Permeability; Caspase 3; Caspase 7; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Female; Fluorescein; Fluorescent Dyes; Fura-2; Hydrogen Peroxide; Mesentery; Microscopy, Confocal; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidants; Perfusion; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Threonine; Time Factors; Venules | 2013 |
Translational fidelity maintenance preventing Ser mis-incorporation at Thr codon in protein from eukaryote.
Topics: Amino Acid Sequence; Anticodon; Arginine; Base Sequence; Codon; Cytoplasm; Isoenzymes; Molecular Sequence Data; Mutation; RNA Editing; RNA, Transfer; RNA, Transfer, Thr; Saccharomyces cerevisiae; Sequence Alignment; Serine; Threonine; Threonine-tRNA Ligase; Transfer RNA Aminoacylation; Tyrosine | 2013 |
Structural and dynamical properties of KTS-disintegrins: A comparison between Obtustatin and Lebestatin.
Topics: Animals; Disintegrins; Lysine; Models, Molecular; Molecular Dynamics Simulation; Serine; Threonine; Viper Venoms; Viperidae | 2013 |
Comprehensive mutational analysis reveals p6Gag phosphorylation to be dispensable for HIV-1 morphogenesis and replication.
Topics: Amino Acid Substitution; gag Gene Products, Human Immunodeficiency Virus; HeLa Cells; HIV-1; Humans; Mass Spectrometry; Mutagenesis, Site-Directed; Phosphorylation; Serine; Threonine; Virus Assembly; Virus Release; Virus Replication | 2013 |
Thymoquinone blocks pSer/pThr recognition by Plk1 Polo-box domain as a phosphate mimic.
Topics: Benzoquinones; Cell Cycle Proteins; Crystallography, X-Ray; Models, Molecular; Phosphates; Phosphorylation; Polo-Like Kinase 1; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Serine; Structure-Activity Relationship; Threonine | 2013 |
Identification and origin of N-linked β-D-N-acetylglucosamine monosaccharide modifications on Arabidopsis proteins.
Topics: Acetylglucosamine; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Asparagine; Chromatography, Affinity; Cytosol; Endoplasmic Reticulum; Enzyme Activation; Glycoside Hydrolases; Glycosylation; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Conformation; Polysaccharides; Protein Folding; Recombinant Proteins; Serine; Threonine | 2013 |
GmDREB2A;2, a canonical DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN2-type transcription factor in soybean, is posttranslationally regulated and mediates dehydration-responsive element-dependent gene expression.
Topics: Adaptation, Physiological; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cell Nucleus; Droughts; Gene Expression Regulation, Plant; Genes, Plant; Germination; Glycine max; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Phenotype; Phylogeny; Plants, Genetically Modified; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Stability; Sequence Homology; Serine; Soybean Proteins; Stress, Physiological; Threonine; Transcription Factors; Transcriptional Activation | 2013 |
An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control.
Topics: Amino Acid Motifs; Computational Biology; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine | 2012 |
Mycobacterium tuberculosis S-adenosyl-l-homocysteine hydrolase is negatively regulated by Ser/Thr phosphorylation.
Topics: Adenosylhomocysteinase; Amino Acid Sequence; Bacterial Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Secondary; Serine; Threonine | 2013 |
Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase.
Topics: Amino Acid Sequence; Cell Line; Cyclin A; Cyclin-Dependent Kinase 2; Elongation Factor 2 Kinase; Humans; Mitosis; Molecular Sequence Data; Peptide Elongation Factor 2; Phosphorylation; Point Mutation; Serine; Threonine | 2013 |
Influence of the O-phosphorylation of serine, threonine and tyrosine in proteins on the amidic ¹⁵N chemical shielding anisotropy tensors.
Topics: Anisotropy; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphates; Phosphorylation; Proteins; Serine; Solvents; Threonine; Tyrosine | 2013 |
Characterization of rare lens epithelium-derived growth factor/p75 genetic variants identified in HIV-1 long-term nonprogressors.
Topics: Adaptor Proteins, Signal Transducing; Anti-HIV Agents; Exons; HIV Integrase; HIV Long-Term Survivors; HIV Seropositivity; Humans; Isoleucine; Point Mutation; Protein Binding; Serine; Threonine; Transcription Factors; Virus Replication | 2013 |
Phosphoproteomic analysis of protein kinase C signaling in Saccharomyces cerevisiae reveals Slt2 mitogen-activated protein kinase (MAPK)-dependent phosphorylation of eisosome core components.
Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Cell Membrane; Cell Wall; Mass Spectrometry; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutation; Phosphopeptides; Phosphoproteins; Phosphorylation; Protein Kinase C; Proteome; Proteomics; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine | 2013 |
LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.
Topics: Amino Acid Sequence; Apolipoproteins E; Cerebrospinal Fluid; Chromatography, Liquid; Glycomics; Glycoproteins; Glycosylation; Hemopexin; Humans; Membrane Proteins; Molecular Conformation; Molecular Sequence Data; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Polysaccharides; Receptor Protein-Tyrosine Kinases; Receptors, G-Protein-Coupled; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Trypsin | 2013 |
Differentiation of opioid drug effects by hierarchical multi-site phosphorylation.
Topics: Analgesics, Opioid; Animals; Endocytosis; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 3; HEK293 Cells; Humans; Mice; Neurons; Phosphorylation; Protein Isoforms; Receptors, Opioid; Serine; Threonine | 2013 |
MS/MS of synthetic peptide is not sufficient to confirm new types of protein modifications.
Topics: Acetylation; Amino Acid Sequence; Animals; Chlorocebus aethiops; COS Cells; HeLa Cells; Histones; Humans; Isoelectric Focusing; Molecular Sequence Data; Peptides; Propionates; Protein Processing, Post-Translational; Sequence Alignment; Serine; Tandem Mass Spectrometry; Threonine | 2013 |
Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1.
Topics: Carrier Proteins; Histones; Humans; Kinetics; mRNA Cleavage and Polyadenylation Factors; Mutagenesis, Site-Directed; Mutant Proteins; Nuclear Proteins; Peptide Fragments; Phosphorylation; Point Mutation; Protein Binding; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Processing, Post-Translational; Recombinant Proteins; RNA Folding; RNA-Binding Proteins; RNA, Messenger; Serine; Threonine; Tyrosine | 2013 |
Phosphorylation at Ser²⁶ in the ATP-binding site of Ca²⁺/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Ferrets; Mutation; Phosphorylation; Protein Isoforms; Serine; Signal Transduction; Threonine | 2013 |
Protein tyrosine phosphatase with proline-glutamine-serine-threonine-rich motifs negatively regulates TLR-triggered innate responses by selectively inhibiting IκB kinase β/NF-κB activation.
Topics: Amino Acid Motifs; Animals; Cell Line; Cells, Cultured; Down-Regulation; Glutamine; HEK293 Cells; Humans; I-kappa B Kinase; Immunity, Innate; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; NF-kappa B; Proline; Protein Interaction Mapping; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Serine; Threonine; Tissue Distribution; Toll-Like Receptors | 2013 |
PMT1 gene plays a major role in O-mannosylation of insulin precursor in Pichia pastoris.
Topics: Animals; Endoplasmic Reticulum; Gene Knockout Techniques; Genome, Fungal; Glycosylation; Insulin; Mannosyltransferases; Pichia; Saccharomyces cerevisiae; Serine; Threonine | 2013 |
Protein lysine-Nζ alkylation and O-phosphorylation mediated by DTT-generated reactive oxygen species.
Topics: Alkylation; Animals; Catalysis; Dithiothreitol; Humans; Lysine; Mutant Proteins; Oxidation-Reduction; Phosphorylation; Protein Conformation; Protein Folding; Proteins; Reactive Oxygen Species; Reducing Agents; Schiff Bases; Serine; Threonine | 2013 |
Testosterone alters maternal vascular adaptations: role of the endothelial NO system.
Topics: Acetylcholine; Adaptation, Physiological; Animals; Arterial Pressure; Biological Factors; Endothelium, Vascular; Epoprostenol; Female; Hypertension, Pregnancy-Induced; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Serine; Testosterone; Threonine; Vasodilator Agents | 2013 |
Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cytoplasm; Humans; Mice; NIH 3T3 Cells; Phosphorylation; Poly A; Poly(A)-Binding Protein I; RNA, Messenger; Serine; Threonine; Transfection | 2013 |
A 19F NMR label to substitute polar amino acids in peptides: a CF3-substituted analogue of serine and threonine.
Topics: Cyclobutanes; Fluorine; Isomerism; Magnetic Resonance Spectroscopy; Peptides; Serine; Threonine | 2013 |
Amino acid building blocks for Fmoc solid-phase synthesis of peptides phosphocholinated at serine, threonine, and tyrosine.
Topics: Amino Acids; Fluorenes; Peptides; Phosphorylcholine; Serine; Solid-Phase Synthesis Techniques; Threonine; Tyrosine | 2013 |
Bioengineering of AAV2 capsid at specific serine, threonine, or lysine residues improves its transduction efficiency in vitro and in vivo.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies, Neutralizing; Antibodies, Viral; Capsid Proteins; Cell Line; Conserved Sequence; Dependovirus; Gene Expression; Gene Transfer Techniques; Genetic Vectors; Hepatocytes; Humans; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Kinase Inhibitors; Sequence Alignment; Serine; Threonine; Transduction, Genetic; Ubiquitination; Viral Load | 2013 |
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.
Topics: Adaptor Proteins, Signal Transducing; Alanine; Animals; Culture Media, Conditioned; Dishevelled Proteins; Gene Expression Regulation; HEK293 Cells; Humans; Mutation; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins; Rats; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Wnt Proteins; Wnt-5a Protein; Wnt3A Protein | 2013 |
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Topics: Animals; Crystallography, X-Ray; Electrophysiology; Female; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Ligand-Gated Ion Channels; Ligands; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Mutation; Oocytes; Protein Structure, Quaternary; Serine; Sodium; Threonine; Water; Xenopus laevis | 2013 |
Human 14-3-3 paralogs differences uncovered by cross-talk of phosphorylation and lysine acetylation.
Topics: 14-3-3 Proteins; Acetylation; Gene Expression Regulation; Humans; Lysine; Phosphorylation; Serine; Threonine | 2013 |
Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency.
Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Amino Acid Substitution; Artemisia annua; Artemisinins; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Leucine; Models, Molecular; Molecular Sequence Data; Monocyclic Sesquiterpenes; Plant Proteins; Protein Engineering; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Sesquiterpenes; Structure-Activity Relationship; Threonine | 2013 |
Targeted modifications in adeno-associated virus serotype 8 capsid improves its hepatic gene transfer efficiency in vivo.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies, Neutralizing; Antibodies, Viral; Capsid Proteins; Cytokines; Dependovirus; Gene Expression; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; Hepatocytes; Humans; Liver; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Sequence Alignment; Serine; Threonine; Transduction, Genetic; Ubiquitination | 2013 |
Global phosphoproteomic analysis reveals diverse functions of serine/threonine/tyrosine phosphorylation in the model cyanobacterium Synechococcus sp. strain PCC 7002.
Topics: Bacteria; Bacterial Proteins; Gene Ontology; Phosphoproteins; Phosphorylation; Photosynthesis; Proteomics; Serine; Signal Transduction; Synechococcus; Threonine; Tyrosine | 2013 |
A maternal diet rich in fish oil may improve cardiac Akt-related signaling in the offspring of diabetic mother rats.
Topics: Animals; Animals, Newborn; Diet, High-Fat; Female; Fish Oils; Hyperglycemia; Hypertriglyceridemia; Hypoglycemic Agents; MAP Kinase Signaling System; Maternal Nutritional Physiological Phenomena; Myometrium; Phosphorylation; Prediabetic State; Pregnancy; Pregnancy in Diabetics; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Serine; Threonine | 2013 |
An enzymatic route to selenazolines.
Topics: Amino Acid Sequence; Cysteine; Iodoacetamide; Multienzyme Complexes; Oxazoles; Peptides, Cyclic; Selenium; Selenocysteine; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles; Threonine | 2013 |
Mitotic phosphorylation of VCIP135 blocks p97ATPase-mediated Golgi membrane fusion.
Topics: Adenosine Triphosphatases; Endopeptidases; Golgi Apparatus; HeLa Cells; Humans; Membrane Fusion; Mitosis; Nuclear Proteins; Phosphorylation; Serine; Threonine | 2013 |
Association study between FSHR Ala307Thr and Ser680Asn variants and polycystic ovary syndrome (PCOS) in Northern Chinese Han women.
Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Asparagine; Case-Control Studies; China; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Geography; Humans; Mutation, Missense; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Receptors, FSH; Serine; Threonine | 2013 |
Total synthesis of daptomycin by cyclization via a chemoselective serine ligation.
Topics: Amino Acids; Anti-Bacterial Agents; Cyclization; Daptomycin; Indicators and Reagents; Kynurenine; Lactams; Ligands; Ozone; Serine; Structure-Activity Relationship; Threonine | 2013 |
Protein chemical synthesis by serine and threonine ligation.
Topics: Acid Anhydride Hydrolases; Acylphosphatase; Aldehydes; Animals; Chromatography, High Pressure Liquid; Corticotropin-Releasing Hormone; Humans; Mass Spectrometry; Molecular Structure; Peptides; Protein Engineering; Serine; Sheep; Teriparatide; Threonine | 2013 |
Changes in the mitochondrial phosphoproteome during mammalian hibernation.
Topics: Animals; Body Temperature; Electrophoresis, Gel, Two-Dimensional; Female; Hibernation; Male; Mammals; Mitochondria, Liver; Mitochondrial Proteins; Oxygen Consumption; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Sciuridae; Seasons; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2013 |
Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
Topics: Amino Acid Sequence; Catalytic Domain; Down Syndrome; Dyrk Kinases; Enzyme Activation; Humans; Models, Molecular; Molecular Sequence Data; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; Substrate Specificity; Threonine | 2013 |
Improved adeno-associated virus (AAV) serotype 1 and 5 vectors for gene therapy.
Topics: Animals; Antibodies, Neutralizing; Capsid Proteins; CHO Cells; Cricetinae; Dependovirus; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Liver; Mice; Mice, Inbred C57BL; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Serine; Threonine; Transduction, Genetic; Ubiquitination | 2013 |
Identification of ubiquitin-modified lysine residues and novel phosphorylation sites on eukaryotic initiation factor 2B epsilon.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Cell Line; Endosomal Sorting Complexes Required for Transport; Epitopes; Eukaryotic Initiation Factor-2B; Humans; Lysine; Mice; Molecular Sequence Data; Nedd4 Ubiquitin Protein Ligases; Phosphorylation; Proteasome Endopeptidase Complex; Protein Binding; Protein Processing, Post-Translational; Rats; Sequence Homology, Amino Acid; Serine; Threonine; Ubiquitin; Ubiquitin-Protein Ligases | 2013 |
Chemoselective fragment condensation between peptide and peptidomimetic oligomers.
Topics: Aldehydes; Amides; Peptides; Peptidomimetics; Peptoids; Serine; Threonine | 2013 |
Conserved water mediated H-bonding dynamics of Ser117 and Thr119 residues in human transthyretin-thyroxin complexation: inhibitor modeling study through docking and molecular dynamics simulation.
Topics: Humans; Hydrogen Bonding; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Multiprotein Complexes; Prealbumin; Protein Binding; Protein Conformation; Protein Multimerization; Serine; Threonine; Thyroxine; Water | 2013 |
Dietary glycine+serine responses of male broilers given low-protein diets with different concentrations of threonine.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Creatine; Diet; Diet, Protein-Restricted; Dietary Proteins; Dietary Supplements; Digestion; Dose-Response Relationship, Drug; Glycine; Male; Pectoralis Muscles; Serine; Threonine; Uric Acid | 2013 |
Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells.
Topics: Angiotensin II; Animals; Cattle; Cell Line; Endothelial Cells; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Zucker; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2013 |
Impairments in site-specific AS160 phosphorylation and effects of exercise training.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Aging; Blotting, Western; Cross-Sectional Studies; Female; Glucose Clamp Technique; GTPase-Activating Proteins; Humans; Insulin; Male; Middle Aged; Muscle, Skeletal; Nuclear Proteins; Nuclear Receptor Interacting Protein 1; Phosphorylation; Physical Endurance; Resistance Training; Sedentary Behavior; Serine; Signal Transduction; Threonine | 2013 |
Site-specific NMR mapping and time-resolved monitoring of serine and threonine phosphorylation in reconstituted kinase reactions and mammalian cell extracts.
Topics: Animals; Cell Extracts; Humans; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Kinases; Protein Structure, Tertiary; Proteins; Serine; Threonine; Time Factors; Tumor Suppressor Protein p53 | 2013 |
Mechanism of dual specificity kinase activity of DYRK1A.
Topics: Animals; Biocatalysis; Dyrk Kinases; Escherichia coli; HeLa Cells; Humans; Kinetics; Models, Molecular; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Serine; Substrate Specificity; Thermodynamics; Threonine; Transfection; Tyrosine | 2013 |
β-adrenergic regulation of the L-type Ca2+ channel does not require phosphorylation of α1C Ser1700.
Topics: Action Potentials; Adrenergic Agents; Alanine; Amino Acid Motifs; Animals; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; Mice; Mutation; Myocytes, Cardiac; Phosphorylation; Proteolysis; Rabbits; Serine; Threonine | 2013 |
Humic acid induces the endothelial nitric oxide synthase phosphorylation at Ser1177 and Thr495 Via Hsp90α and Hsp90β upregulation in human umbilical vein endothelial cells.
Topics: Adult; Calcium; Chelating Agents; Egtazic Acid; Female; HSP90 Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; Humic Substances; L-Lactate Dehydrogenase; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Phosphorylation; Pregnancy; Serine; Soil; Threonine | 2015 |
Identification of two ATR-dependent phosphorylation sites on coronavirus nucleocapsid protein with nonessential functions in viral replication and infectivity in cultured cells.
Topics: Amino Acid Substitution; Animals; Cell Line; Chlorocebus aethiops; Coronavirus Nucleocapsid Proteins; DNA Mutational Analysis; Infectious bronchitis virus; Mutagenesis, Site-Directed; Nucleocapsid Proteins; Phosphorylation; Protein Processing, Post-Translational; Serine; Threonine; Vero Cells | 2013 |
CK1δ kinase activity is modulated by Chk1-mediated phosphorylation.
Topics: Amino Acid Sequence; Animals; Casein Kinase Idelta; Cell Line, Tumor; Checkpoint Kinase 1; Fibroblasts; Gene Expression Regulation; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinases; Rats; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine | 2013 |
Role of methyl-induced polarization in ion binding.
Topics: Algorithms; Amino Acid Substitution; Barium; Binding Sites; Ion Channel Gating; Ion Transport; Models, Chemical; Models, Molecular; Potassium; Potassium Channels; Protein Structure, Tertiary; Serine; Thermodynamics; Threonine | 2013 |
Phosphorylation regulates FOXC2-mediated transcription in lymphatic endothelial cells.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Chlorocebus aethiops; COS Cells; Endothelial Cells; Forkhead Transcription Factors; Gene Expression Regulation; HEK293 Cells; Hep G2 Cells; Humans; Immunoblotting; Mice; Mice, Transgenic; Microscopy, Confocal; Molecular Sequence Data; Mutation; Oligonucleotide Array Sequence Analysis; Phosphorylation; Proline; Reverse Transcriptase Polymerase Chain Reaction; Serine; Threonine; Transcription, Genetic | 2013 |
Synthesis of human growth hormone-releasing hormone via three-fragment serine/threonine ligation (STL).
Topics: Growth Hormone-Releasing Hormone; Humans; Molecular Structure; Peptide Fragments; Serine; Threonine | 2013 |
Arabidopsis casein kinase1 proteins CK1.3 and CK1.4 phosphorylate cryptochrome2 to regulate blue light signaling.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Casein Kinase I; Cotyledon; Cryptochromes; Flowers; Gene Expression Regulation, Plant; Hypocotyl; Immunoblotting; Light; Luminescent Proteins; Microscopy, Confocal; Models, Genetic; Molecular Sequence Data; Mutation; Phosphorylation; Phylogeny; Plant Leaves; Plants, Genetically Modified; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine | 2013 |
Multisite light-induced phosphorylation of the transcription factor PIF3 is necessary for both its rapid degradation and concomitant negative feedback modulation of photoreceptor phyB levels in Arabidopsis.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Feedback, Physiological; Immunoblotting; Light; Molecular Sequence Data; Mutation; Phosphorylation; Phytochrome B; Plants, Genetically Modified; Proteolysis; Reverse Transcriptase Polymerase Chain Reaction; Seedlings; Serine; Tandem Mass Spectrometry; Threonine | 2013 |
Evolutionary conservation of mammalian sperm proteins associates with overall, not tyrosine, phosphorylation in human spermatozoa.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Conserved Sequence; Electrophoresis, Gel, Two-Dimensional; Evolution, Molecular; Fertility; Gene Expression Regulation; Humans; Male; Molecular Sequence Annotation; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; Spermatozoa; Threonine; Tyrosine | 2013 |
A dileucine motif is involved in plasma membrane expression and endocytosis of rat sodium taurocholate cotransporting polypeptide (Ntcp).
Topics: Amino Acid Motifs; Animals; Cell Membrane; Clathrin; Endocytosis; Gene Expression Regulation; Hep G2 Cells; Humans; Leucine; Organic Anion Transporters, Sodium-Dependent; Protein Transport; Rats; Serine; Symporters; Threonine | 2013 |
In vivo peripheral nervous system insulin signaling.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Proto-Oncogene Proteins c-akt; Sciatic Nerve; Serine; Signal Transduction; Threonine; Time Factors | 2013 |
Three most common nonsynonymous UGT1A6*2 polymorphisms (Thr181Ala, Arg184Ser and Ser7Ala) and therapeutic response to deferiprone in β-thalassemia major patients.
Topics: Adolescent; Alanine; Amino Acid Substitution; Arginine; beta-Thalassemia; Child; Child, Preschool; Deferiprone; Female; Gene Frequency; Genetic Association Studies; Glucuronosyltransferase; Humans; Iron Chelating Agents; Iron Overload; Isoenzymes; Male; Mutation, Missense; Polymorphism, Single Nucleotide; Pyridones; Serine; Threonine; Treatment Outcome | 2013 |
Phosphorylation of the Drosophila transient receptor potential ion channel is regulated by the phototransduction cascade and involves several protein kinases and phosphatases.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Drosophila melanogaster; Drosophila Proteins; Light; Mass Spectrometry; Molecular Sequence Data; Mutation; Phosphoric Monoester Hydrolases; Phosphorylation; Photoreceptor Cells, Invertebrate; Protein Kinase C; Protein Kinases; Serine; Threonine; Transient Receptor Potential Channels; Tryptophan | 2013 |
The presence of modifiable residues in the core peptide part of precursor nisin is not crucial for precursor nisin interactions with NisB- and NisC.
Topics: Anti-Infective Agents; Bacterial Proteins; Cloning, Molecular; Cysteine; Genetic Variation; Intramolecular Lyases; Lactococcus lactis; Membrane Proteins; Nisin; Peptides; Plasmids; Protein Binding; Protein Engineering; Protein Structure, Tertiary; Recombination, Genetic; Serine; Substrate Specificity; Threonine | 2013 |
Chromatin PTEN is involved in DNA damage response partly through regulating Rad52 sumoylation.
Topics: Active Transport, Cell Nucleus; Casein Kinase II; Cell Nucleus; Chromatin; Cytoplasm; DNA Damage; DNA Repair; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; HeLa Cells; Histones; Humans; Hydrogen Peroxide; Phosphorylation; PTEN Phosphohydrolase; Rad52 DNA Repair and Recombination Protein; Serine; Signal Transduction; Sumoylation; Threonine | 2013 |
O-GlcNAcPRED: a sensitive predictor to capture protein O-GlcNAcylation sites.
Topics: Acetylation; Glycosylation; Humans; Models, Biological; Protein Processing, Post-Translational; Proteins; Reproducibility of Results; Sensitivity and Specificity; Serine; Support Vector Machine; Threonine | 2013 |
Detection of phospho-sites generated by protein kinase CK2 in CFTR: mechanistic aspects of Thr1471 phosphorylation.
Topics: Amino Acid Sequence; Animals; Casein Kinase II; Cell Line; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Kinetics; Mass Spectrometry; Mice; Models, Molecular; Molecular Sequence Data; Naphthyridines; Phenazines; Phosphopeptides; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Stability; Saccharomyces cerevisiae; Serine; Threonine | 2013 |
O-linked protein glycosylation in Mycoplasma.
Topics: Amino Acid Sequence; Bacterial Proteins; Glycoproteins; Glycosylation; Glycosyltransferases; Mass Spectrometry; Mycoplasma arthritidis; Peptide Mapping; Polysaccharides, Bacterial; Protein Processing, Post-Translational; Serine; Threonine | 2013 |
Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates.
Topics: Adult; Aged, 80 and over; Alanine; Amino Acid Sequence; Aminobutyrates; Cell Nucleus; Cross-Linking Reagents; Crystallins; Glutathione; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Peptides; Protein Processing, Post-Translational; Serine; Tandem Mass Spectrometry; Threonine; Time Factors | 2014 |
Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication.
Topics: Amino Acid Sequence; Blotting, Western; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Chromosomal Proteins, Non-Histone; DNA Damage; DNA Replication; Molecular Sequence Data; Multiprotein Complexes; Mutation; Phosphorylation; Protein Binding; Saccharomyces cerevisiae Proteins; Serine; Telomerase; Telomere; Telomere Homeostasis; Telomere-Binding Proteins; Threonine; Time Factors; Two-Hybrid System Techniques | 2014 |
PI3 kinase directly phosphorylates Akt1/2 at Ser473/474 in the insulin signal transduction pathway.
Topics: 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Blotting, Western; Glucose; Glucose Transporter Type 4; Heterocyclic Compounds, 3-Ring; Hypoglycemic Agents; Insulin; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA Interference; Serine; Signal Transduction; Threonine; Wortmannin | 2014 |
Regulation of autophosphorylation controls PLK4 self-destruction and centriole number.
Topics: Amino Acid Sequence; Animals; Animals, Genetically Modified; Cell Cycle Proteins; Centrioles; Drosophila; Drosophila Proteins; Female; Gene Expression Regulation; Male; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Ubiquitin-Protein Ligases | 2013 |
A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation.
Topics: Fluorescent Dyes; Hydroxylysine; Peptide Fragments; Proteins; Serine; Threonine | 2014 |
Molecular determinants of orexin receptor-arrestin-ubiquitin complex formation.
Topics: Amino Acid Sequence; Arrestin; DNA, Complementary; Glutamic Acid; HEK293 Cells; Humans; Inositol Phosphates; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Mutagenesis; Neuropeptides; Orexin Receptors; Orexins; Serine; Threonine; Ubiquitin | 2014 |
AT1 receptor blocker potentiates shear-stress induced nitric oxide production via modulation of eNOS phosphorylation of residues Thr(495) and Ser(1177.).
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Calcium; Cell Line, Tumor; Endothelial Cells; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Receptor, Angiotensin, Type 1; Serine; Shear Strength; Stress, Mechanical; Telmisartan; Tetrazoles; Threonine | 2013 |
Detection and characterization of serine and threonine hydroxyl protons in Bacillus circulans xylanase by NMR spectroscopy.
Topics: Bacillus; Endo-1,4-beta Xylanases; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protons; Serine; Threonine | 2014 |
Altered human gut dendritic cell properties in ulcerative colitis are reversed by Lactobacillus plantarum extracellular encrypted peptide STp.
Topics: Adult; Antigens, CD; B7-1 Antigen; Case-Control Studies; CD40 Antigens; Cell Adhesion Molecules; Cell Proliferation; Colitis, Ulcerative; Dendritic Cells; Female; Gastrointestinal Tract; Healthy Volunteers; Humans; Immunohistochemistry; Inflammatory Bowel Diseases; Lactobacillus plantarum; Lectins, C-Type; Male; Mannose-Binding Lectins; Membrane Glycoproteins; Middle Aged; Peptides; Probiotics; Receptors, Cell Surface; Receptors, Immunologic; Serine; T-Lymphocytes; Threonine; Toll-Like Receptors | 2014 |
PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adaptor Proteins, Signal Transducing; Adenosine Triphosphate; Blood Platelets; Cells, Cultured; Clot Retraction; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Oncogene Protein v-akt; Phosphorylation; Platelet Activation; Pyrimidines; Receptors, Thrombin; Serine; Signal Transduction; Thiophenes; Threonine; Thromboxanes | 2014 |
Molecular interactions between general anesthetics and the 5HT2B receptor.
Topics: Anesthetics, General; Binding Sites; Binding, Competitive; Humans; Hydrogen Bonding; Isoflurane; Kinetics; Models, Molecular; Molecular Conformation; Propofol; Protein Structure, Tertiary; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Serine; Signal Transduction; Static Electricity; Threonine | 2015 |
Inhibition of serine/threonine protein phosphatase PP1 protects cardiomyocytes from tunicamycin-induced apoptosis and I/R through the upregulation of p-eIF2α.
Topics: Animals; Apoptosis; Cell Survival; Eukaryotic Initiation Factor-2; Myocytes, Cardiac; Phosphoprotein Phosphatases; Phosphorylation; Pyrazoles; Pyrimidines; Rats; Reperfusion Injury; Serine; Threonine; Tunicamycin | 2014 |
Children with severe asthma have unique oxidative stress-associated metabolomic profiles.
Topics: Adolescent; Adrenal Cortex Hormones; Asthma; Child; Chromatography, High Pressure Liquid; Computational Biology; Drug Resistance; Ethanolamines; Female; Glycine; Humans; Lipid Peroxidation; Male; Metabolome; Oxidative Stress; Serine; Sphingosine N-Acyltransferase; Threonine | 2014 |
Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacterial Proteins; Carbazoles; Gene Expression Regulation, Bacterial; Indole Alkaloids; Mycobacterium tuberculosis; Oxygen; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine | 2014 |
Exon resequencing of the gene encoding UCma/GRP reveals a common carboxy-terminal 138Thr > Ser polymorphism.
Topics: Base Sequence; Case-Control Studies; DNA Primers; Exons; Humans; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Kidney Failure, Chronic; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proteins; Serine; Sweden; Threonine | 2013 |
Mechanisms of homologous and heterologous phosphorylation of FFA receptor 4 (GPR120): GRK6 and PKC mediate phosphorylation of Thr³⁴⁷, Ser³⁵⁰, and Ser³⁵⁷ in the C-terminal tail.
Topics: Amino Acid Sequence; G-Protein-Coupled Receptor Kinases; HEK293 Cells; Humans; Molecular Sequence Data; Mutation; Peptide Fragments; Phosphorylation; Protein Kinase C; Receptors, G-Protein-Coupled; Sequence Homology, Amino Acid; Serine; Threonine | 2014 |
Molecular characterization of an alanine-, proline-, glycine-, threonine-, and serine-rich protein of the hard tick Haemaphysalis qinghaiensis and its effect as a vaccine against tick infestation in sheep.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Glycine; Immunity, Active; Ixodidae; Molecular Sequence Data; Phylogeny; Proline; Rabbits; Recombinant Proteins; Sequence Analysis, DNA; Serine; Sheep; Sheep Diseases; Threonine; Tick Infestations; Vaccination; Vaccines | 2014 |
Regulation of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor function by protein kinase C at serine-818 and threonine-840.
Topics: Animals; Female; HEK293 Cells; Hippocampus; Humans; Male; Mice; Models, Molecular; Mutation; Neurons; Patch-Clamp Techniques; Phosphorylation; Primary Cell Culture; Protein Conformation; Protein Kinase C; Rats; Receptors, AMPA; Serine; Threonine | 2014 |
Crystal structures of the phosphorylated BRI1 kinase domain and implications for brassinosteroid signal initiation.
Topics: Arabidopsis; Arabidopsis Proteins; Brassinosteroids; Mutation; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine | 2014 |
Distinct and site-specific phosphorylation of the retinoblastoma protein at serine 612 in differentiated cells.
Topics: Cell Differentiation; Chromatin; DNA-Binding Proteins; E2F1 Transcription Factor; Humans; K562 Cells; Nuclear Proteins; Phosphorylation; Retinoblastoma Protein; Serine; Threonine; U937 Cells | 2014 |
Global phosphoproteomic analysis of Daphnia pulex reveals evolutionary conservation of Ser/Thr/Tyr phosphorylation.
Topics: Amino Acid Sequence; Animals; Arthropod Proteins; Biological Evolution; Conserved Sequence; Daphnia; Gene Expression Regulation; Humans; Molecular Sequence Annotation; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Proteomics; Serine; Threonine; Titanium; Tyrosine | 2014 |
Hb A2-Konz [δ50(D1)Ser → Thr; HBD: c.151T > A]: a new δ chain hemoglobin variant characterized by mass spectrometry and high performance liquid chromatography.
Topics: Aged; Chromatography, High Pressure Liquid; delta-Globins; Female; Hemoglobin A2; Hemoglobins, Abnormal; Humans; Mutation, Missense; Serine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Threonine | 2014 |
Azilsartan, an angiotensin II type 1 receptor blocker, restores endothelial function by reducing vascular inflammation and by increasing the phosphorylation ratio Ser(1177)/Thr(497) of endothelial nitric oxide synthase in diabetic mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Organ Culture Techniques; Oxadiazoles; Phosphorylation; Serine; Threonine; Vasculitis; Vasodilation | 2014 |
Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Aging; Animals; Cyclic AMP-Dependent Protein Kinases; Food; Gene Expression Regulation, Fungal; Glucose; Longevity; Mice; Protein Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Stress, Physiological; Threonine; Transcription Factors; Valine | 2014 |
Influence of amino acid stereocenters on the formation of bicyclic N,O-acetals.
Topics: Acetals; Amino Acids; Bridged Bicyclo Compounds, Heterocyclic; Serine; Stereoisomerism; Thermodynamics; Threonine | 2014 |
The nucleotide-binding oligomerization domain-containing protein 1 (NOD1) polymorphism S7N does not affect receptor function.
Topics: Amino Acid Sequence; Binding Sites; Black or African American; HEK293 Cells; Humans; Immunoblotting; Luciferases; Models, Molecular; Molecular Sequence Data; Mutation; NF-kappa B; Nod1 Signaling Adaptor Protein; Phosphorylation; Polymorphism, Genetic; Protein Structure, Tertiary; Serine; Signal Transduction; Threonine; Tyrosine; White People | 2014 |
Phosphoregulation of the human SMN complex.
Topics: Amino Acid Sequence; Coiled Bodies; HeLa Cells; Humans; Molecular Sequence Data; Mutation; Phosphoproteins; Phosphorylation; Proteome; Ribonucleoproteins, Small Nuclear; Serine; SMN Complex Proteins; Threonine; Tyrosine | 2014 |
Hydrogen bonding constrains free radical reaction dynamics at serine and threonine residues in peptides.
Topics: Electron Transport; Free Radicals; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Nitrogen; Sequence Analysis, Protein; Serine; Thermodynamics; Threonine | 2014 |
Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.
Topics: Animals; Anisomycin; Antigens, CD; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Receptor, Insulin; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Signal Transduction; Thapsigargin; Threonine; TOR Serine-Threonine Kinases; Tunicamycin; Tyrosine | 2014 |
Ser/Thr/Tyr phosphoproteome characterization of Acinetobacter baumannii: comparison between a reference strain and a highly invasive multidrug-resistant clinical isolate.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Chromatography; Drug Resistance, Multiple, Bacterial; Glycolysis; Mass Spectrometry; Molecular Sequence Data; Peptides; Phenotype; Phosphorylation; Proteome; Proteomics; Serine; Tandem Mass Spectrometry; Threonine; Titanium; Tyrosine | 2014 |
The Mycobacterium tuberculosis transcriptional repressor EthR is negatively regulated by Serine/Threonine phosphorylation.
Topics: Amino Acid Sequence; Antitubercular Agents; Bacterial Proteins; Ethionamide; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Phosphorylation; Protein Serine-Threonine Kinases; Repressor Proteins; Serine; Threonine; Tuberculosis | 2014 |
Metabolomics of asthma.
Topics: Asthma; Carnitine; Ethanolamines; Female; Glycine; Humans; Male; Methylamines; Oxidative Stress; Serine; Sphingosine N-Acyltransferase; Threonine | 2014 |
Reply: To PMID 24369803.
Topics: Asthma; Carnitine; Ethanolamines; Female; Glycine; Humans; Male; Methylamines; Oxidative Stress; Serine; Sphingosine N-Acyltransferase; Threonine | 2014 |
Reply: To PMID 24369802.
Topics: Asthma; Ethanolamines; Female; Glycine; Humans; Male; Oxidative Stress; Serine; Sphingosine N-Acyltransferase; Threonine | 2014 |
Inhibitory interactions between phosphorylation sites in the C terminus of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor GluA1 subunits.
Topics: Animals; Binding Sites; Blotting, Western; Calcium; Calcium Channels; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Hippocampus; Humans; Male; Marine Toxins; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Okadaic Acid; Oxazoles; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Phosphatase 2; Protein Subunits; Receptors, AMPA; Serine; Threonine | 2014 |
Blue light-induced proteomic changes in etiolated Arabidopsis seedlings.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Blotting, Western; Carrier Proteins; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Etiolation; Green Fluorescent Proteins; Light; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proteome; Proteomics; Seedlings; Sequence Homology, Amino Acid; Serine; Threonine | 2014 |
Plasma anti-α-galactoside antibody binds to serine- and threonine-rich peptide sequence of apo(a) subunit in Lp(a).
Topics: Amino Acid Motifs; Antigen-Antibody Complex; Apolipoproteins A; Binding Sites; Galactosides; Humans; Immunoglobulin G; Serine; Threonine | 2014 |
Apolipoprotein E4 impairs in vivo hippocampal long-term synaptic plasticity by reducing the phosphorylation of CaMKIIα and CREB.
Topics: Analysis of Variance; Animals; Apolipoprotein E4; Biophysics; Calcium-Calmodulin-Dependent Protein Kinase Type 2; CREB-Binding Protein; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Long-Term Potentiation; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Threonine | 2014 |
Development and application of serine/threonine ligation for synthetic protein chemistry.
Topics: Acid Anhydride Hydrolases; Acylphosphatase; Amino Acid Sequence; Chemistry Techniques, Synthetic; Erythrocytes; Esters; Molecular Sequence Data; Mucin-1; Peptides, Cyclic; Serine; Threonine | 2014 |
mTORC1 and JNK coordinate phosphorylation of the p70S6K1 autoinhibitory domain in skeletal muscle following functional overloading.
Topics: Animals; Carrier Proteins; Cumulative Trauma Disorders; Disease Models, Animal; HEK293 Cells; Humans; Insulin-Like Growth Factor I; Male; MAP Kinase Signaling System; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Mitogen-Activated Protein Kinase 8; Multiprotein Complexes; Muscle, Skeletal; Phosphorylation; Protein Interaction Domains and Motifs; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rapamycin-Insensitive Companion of mTOR Protein; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Serine; Threonine; TOR Serine-Threonine Kinases | 2014 |
The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation.
Topics: Animals; Brain; Cell Cycle; Cell Differentiation; Cell Line; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Down Syndrome; Dyrk Kinases; Humans; Mice, Inbred ICR; Neurogenesis; Neurons; Phosphorylation; Primary Cell Culture; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; Threonine | 2014 |
Phosphoacceptors threonine 162 and serines 170 and 178 within the carboxyl-terminal RRRS/T motif of the hepatitis B virus core protein make multiple contributions to hepatitis B virus replication.
Topics: Amino Acid Motifs; Amino Acid Sequence; Cell Line, Tumor; DNA Replication; DNA, Viral; Genome, Viral; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Core Antigens; Hepatitis B virus; Humans; Mutation; Phosphorylation; Serine; Threonine; Viral Core Proteins; Virus Replication | 2014 |
Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs.
Topics: 14-3-3 Proteins; Adenocarcinoma; Amino Acid Motifs; Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Survival; Cell Transformation, Neoplastic; Chromatography, Affinity; Gene Knockdown Techniques; Heterografts; Humans; Immunoprecipitation; Lung Neoplasms; Mice; Mice, SCID; Microfilament Proteins; Mutagenesis, Site-Directed; Neoplasm Invasiveness; Phosphorylation; RNA, Small Interfering; Serine; src Homology Domains; Threonine; Transfection | 2014 |
Free amino acids in stimulated and unstimulated whole saliva: advantages or disadvantages.
Topics: Amino Acids; Chromatography, Liquid; Citrulline; Cross-Sectional Studies; Dental Caries; Female; Glutamine; Humans; Male; Ornithine; Phenylalanine; Saliva; Serine; Threonine; Young Adult | 2014 |
Inhibition of protein phosphatase 2A (PP2A) prevents Mcl-1 protein dephosphorylation at the Thr-163/Ser-159 phosphodegron, dramatically reducing expression in Mcl-1-amplified lymphoma cells.
Topics: Binding Sites; Burkitt Lymphoma; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression; Gene Knockdown Techniques; Humans; MAP Kinase Signaling System; Marine Toxins; Myeloid Cell Leukemia Sequence 1 Protein; Okadaic Acid; Oxazoles; Phosphorylation; Protein Phosphatase 2; Proteolysis; Serine; Tetradecanoylphorbol Acetate; Threonine | 2014 |
Integrated stability and activity control of the Drosophila Rbf1 retinoblastoma protein.
Topics: Animals; Animals, Genetically Modified; Binding Sites; Blotting, Western; Cell Line; Cyclin-Dependent Kinases; Cyclins; Drosophila Proteins; Eye; Humans; Lysine; Microscopy, Electron; Mutation; Phosphorylation; Protein Stability; Retinoblastoma Protein; Serine; Threonine; Transcription Factors; Wings, Animal | 2014 |
The six conserved serine/threonine sites of REPRESSOR OF ga1-3 protein are important for its functionality and stability in gibberellin signaling in Arabidopsis.
Topics: Amino Acid Substitution; Arabidopsis; Arabidopsis Proteins; Gibberellins; Mutation; Phenotype; Phosphorylation; Plant Growth Regulators; Plants, Genetically Modified; Protein Stability; Repressor Proteins; Serine; Signal Transduction; Threonine; Triazoles; Two-Hybrid System Techniques | 2014 |
The influence of Ser-154, Cys-113, and the phosphorylated threonine residue on the catalytic reaction mechanism of Pin1.
Topics: Binding Sites; Biocatalysis; Catalytic Domain; Cysteine; Humans; Hydrogen Bonding; Isomerism; Molecular Dynamics Simulation; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Quantum Theory; Serine; Static Electricity; Substrate Specificity; Thermodynamics; Threonine | 2014 |
Serine versus threonine glycosylation with α-O-GalNAc: unexpected selectivity in their molecular recognition with lectins.
Topics: Amino Acid Sequence; Antigens, Tumor-Associated, Carbohydrate; Glycopeptides; Glycosylation; Lectins; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Plant Lectins; Serine; Soybean Proteins; Threonine | 2014 |
Understanding the determinants of substrate specificity in IMP family metallo-β-lactamases: the importance of residue 262.
Topics: Amino Acid Substitution; Bacterial Proteins; beta-Lactamases; Catalytic Domain; Cephalothin; Genetic Variation; Gram-Negative Bacteria; Models, Molecular; Protein Structure, Secondary; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine; Valine | 2014 |
Improvement of Trichoderma reesei xylanase II thermal stability by serine to threonine surface mutations.
Topics: Amino Acid Substitution; Endo-1,4-beta Xylanases; Enzyme Stability; Escherichia coli; Kinetics; Mutation; Protein Conformation; Protein Engineering; Serine; Temperature; Threonine; Trichoderma | 2015 |
Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling.
Topics: Algorithms; HeLa Cells; Humans; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Proteome; Sequence Analysis, Protein; Serine; Signal Transduction; Threonine; Tyrosine | 2014 |
Dipalmitoleoylphosphoethanolamine as a PP2A enhancer obstructs insulin signaling by promoting Ser/Thr dephosphorylation of Akt.
Topics: 3T3-L1 Cells; Animals; Enzyme Activation; Ethanolamines; Fatty Acids, Unsaturated; Humans; Insulin; Mice; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine | 2014 |
Copper(II)-mediated O-arylation of protected serines and threonines.
Topics: Amino Acids; Boronic Acids; Catalysis; Copper; Molecular Structure; Serine; Threonine | 2014 |
Dynamic autophosphorylation of mps1 kinase is required for faithful mitotic progression.
Topics: Cell Cycle Proteins; HeLa Cells; Humans; Mitosis; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; Threonine | 2014 |
Tissue-specific distribution of serine/threonine protein phosphatase 1 of Toxocara canis.
Topics: Amino Acid Sequence; Animals; Gene Expression; Male; Models, Structural; Organ Specificity; Phosphoprotein Phosphatases; Rabbits; Recombinant Proteins; Serine; Spermatozoa; Testis; Threonine; Toxocara canis; Toxocariasis | 2014 |
UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase from the snail Biomphalaria glabrata - substrate specificity and preference of glycosylation sites.
Topics: Acetylgalactosamine; Acetylglucosamine; Amino Acid Motifs; Animals; Binding Sites; Biomphalaria; Galactose; Gene Expression; Glucose; Glycosylation; Kinetics; Molecular Sequence Data; N-Acetylgalactosaminyltransferases; Peptides; Polypeptide N-acetylgalactosaminyltransferase; Protein Binding; Recombinant Proteins; Serine; Sf9 Cells; Spodoptera; Substrate Specificity; Threonine | 2014 |
Combined correlation-based network and mQTL analyses efficiently identified loci for branched-chain amino acid, serine to threonine, and proline metabolism in tomato seeds.
Topics: Amino Acids, Branched-Chain; Chromosomes, Plant; Circadian Clocks; Computer Simulation; DNA, Plant; Gene Expression Regulation, Plant; Light; Metabolic Networks and Pathways; Metabolomics; Proline; Proline Oxidase; Quantitative Trait Loci; Seeds; Sequence Analysis, DNA; Serine; Solanum lycopersicum; Threonine | 2015 |
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB.
Topics: Bacterial Proteins; Bacteriocins; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Hydro-Lyases; Lactococcus lactis; Membrane Proteins; Models, Molecular; Nisin; Phylogeny; Protein Structure, Tertiary; RNA, Transfer, Glu; Serine; Threonine | 2015 |
Dexmedetomidine directly increases tau phosphorylation.
Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Brain; Cells, Cultured; Cerebral Cortex; Dexmedetomidine; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Male; Neurons; Okadaic Acid; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; tau Proteins; Threonine; Time Factors | 2015 |
Quantitative proteome analyses identify PrfA-responsive proteins and phosphoproteins in Listeria monocytogenes.
Topics: Bacterial Proteins; Binding Sites; Chromatography, Liquid; Culture Media; Glucose; Listeria monocytogenes; Mutation; Peptide Termination Factors; Peptides; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Purines; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine; Virulence | 2014 |
Prediction of serine/threonine phosphorylation sites in bacteria proteins.
Topics: Algorithms; Bacterial Proteins; Phosphorylation; Serine; Threonine | 2015 |
Phosphorylation of AKT(Ser473) serves as an independent prognostic marker for radiosensitivity in advanced head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Chromones; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Morpholines; Multivariate Analysis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Serine; Survival Analysis; Threonine; Tissue Culture Techniques | 2015 |
Echinochrome A regulates phosphorylation of phospholamban Ser16 and Thr17 suppressing cardiac SERCA2A Ca²⁺ reuptake.
Topics: Animals; Calcium Signaling; Calcium-Binding Proteins; Cardiotonic Agents; Cells, Cultured; Heart Ventricles; Male; Myocardial Contraction; Myocytes, Cardiac; Naphthoquinones; Phosphorylation; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Threonine; Ventricular Function | 2015 |
Kinetic analysis of BCL11B multisite phosphorylation-dephosphorylation and coupled sumoylation in primary thymocytes by multiple reaction monitoring mass spectroscopy.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Calcimycin; Calcium Ionophores; Cells, Cultured; Immunoblotting; Kinetics; Lysine; Mass Spectrometry; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phorbol 12,13-Dibutyrate; Phosphorylation; Repressor Proteins; Serine; Sumoylation; Threonine; Thymocytes; Time Factors; Tumor Suppressor Proteins | 2014 |
Traceless splicing enabled by substrate-induced activation of the Nostoc punctiforme Npu DnaE intein after mutation of a catalytic cysteine to serine.
Topics: Aldehyde-Lyases; Amino Acid Sequence; Bacterial Proteins; Blotting, Western; Catalytic Domain; Cysteine; DNA Polymerase III; Enzyme Activation; Escherichia coli Proteins; Exteins; Inteins; Molecular Sequence Data; Mutation, Missense; Nostoc; Protein Splicing; Serine; Substrate Specificity; Threonine | 2014 |
Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Cell Line, Tumor; Colorectal Neoplasms; Genes, ras; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Oncogenes; Phosphorylation; Serine; Signal Transduction; Threonine; Transcription Factor 4; Transcription Factors; Wnt Signaling Pathway | 2015 |
Interactions with the bifunctional interface of the transcriptional coactivator DCoH1 are kinetically regulated.
Topics: Animals; Chromatography, Gel; Crystallography, X-Ray; Hydro-Lyases; Kinetics; Mice; Models, Molecular; Mutation; Protein Conformation; Protein Folding; Protein Multimerization; Serine; Threonine; Water | 2015 |
Synthesis and cell-selective antitumor properties of amino acid conjugated tumor-associated carbohydrate antigen-coated gold nanoparticles.
Topics: Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chemistry Techniques, Synthetic; Gold; Humans; Metal Nanoparticles; Serine; Threonine | 2015 |
Molecular basis of E. coli L-threonine aldolase catalytic inactivation at low pH.
Topics: Catalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Glycine Hydroxymethyltransferase; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Protein Binding; Pyridoxal Phosphate; Serine; Threonine | 2015 |
Using support vector machines to identify protein phosphorylation sites in viruses.
Topics: Amino Acid Sequence; Databases, Protein; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Structure, Tertiary; Serine; Support Vector Machine; Threonine; Tyrosine; Viral Proteins | 2015 |
Why Ser and not Thr brokers catalysis in the trypsin fold.
Topics: Allosteric Regulation; Amino Acid Chloromethyl Ketones; Amino Acid Substitution; Catalytic Domain; Crystallography, X-Ray; HEK293 Cells; Humans; Models, Molecular; Point Mutation; Protein Conformation; Serine; Threonine; Thrombin; Trypsin | 2015 |
Evidence that phosphorylation of threonine in the GT motif triggers activation of PknA, a eukaryotic-type serine/threonine kinase from Mycobacterium tuberculosis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; Molecular Sequence Data; Mutant Proteins; Mycobacterium tuberculosis; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Threonine | 2015 |
Communication between the N and C termini is required for copper-stimulated Ser/Thr phosphorylation of Cu(I)-ATPase (ATP7B).
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Biological Transport; Cation Transport Proteins; Cell Line; Copper; Copper-Transporting ATPases; Humans; Molecular Sequence Data; Phosphorylation; Serine; Threonine | 2015 |
TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport.
Topics: alpha-Macroglobulins; Animals; Blood-Brain Barrier; Blotting, Western; Calcium; Cells, Cultured; Cerebrospinal Fluid; Choroid Plexus; Epithelial Cells; Humans; Leucine; Mice; Microscopy, Confocal; Phosphorylation; Primary Cell Culture; Protein Transport; Serine; Sulfonamides; Swine; Threonine; TRPV Cation Channels | 2015 |
Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Topics: Alagille Syndrome; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Conserved Sequence; Crystallography, X-Ray; Fucose; Glucose; Glycosylation; Intracellular Signaling Peptides and Proteins; Ligands; Membrane Proteins; Molecular Sequence Data; Molecular Targeted Therapy; Polysaccharides; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Protein Structure, Tertiary; Rats; Receptor, Notch1; Serine; Threonine | 2015 |
Dynamical role of phosphorylation on serine/threonine-proline Pin1 substrates from constant force molecular dynamics simulations.
Topics: Diffusion; Friction; Isomerism; Kinetics; Molecular Dynamics Simulation; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Folding; Rotation; Serine; Threonine | 2015 |
α-Thalassemia associated with hb instability: a tale of two features. the case of Hb Rogliano or α1 Cod 108(G15)Thr→Asn and Hb Policoro or α2 Cod 124(H7)Ser→Pro.
Topics: Adolescent; Adult; Aged; alpha-Thalassemia; Asparagine; Base Sequence; Child; DNA Mutational Analysis; Exons; Female; Genotype; Hemoglobins, Abnormal; Humans; Male; Middle Aged; Pedigree; Polymorphism, Single Nucleotide; Proline; Protein Stability; Protein Structure, Quaternary; Protein Structure, Tertiary; RNA, Messenger; Serine; Threonine; Young Adult | 2015 |
Excess of threonine compared with serine promotes threonine aldolase activity in Lactococcus lactis IL1403.
Topics: Amino Acids; Biomass; Glycine Hydroxymethyltransferase; Lactococcus lactis; Metabolic Networks and Pathways; Proteomics; Serine; Threonine | 2015 |
Analysis of the Candida albicans Phosphoproteome.
Topics: Candida albicans; Fungal Proteins; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Serine; Threonine | 2015 |
Exogenous glycine and serine promote growth and antifungal activity of Penicillium citrinum W1 from the south-west Indian Ocean.
Topics: Antifungal Agents; Fungal Proteins; Geologic Sediments; Glycine; Indian Ocean; Metabolic Networks and Pathways; Metabolome; Penicillium; Serine; Threonine | 2015 |
Phosphorylation of PTEN at STT motif is associated with DNA damage response.
Topics: Amino Acid Sequence; Cells, Cultured; DNA Damage; DNA Repair; Etoposide; HEK293 Cells; Humans; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; PTEN Phosphohydrolase; Serine; Threonine | 2014 |
Protein Kinase A (PKA) Phosphorylation of Shp2 Protein Inhibits Its Phosphatase Activity and Modulates Ligand Specificity.
Topics: Animals; Cardiomegaly; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Humans; Ligands; Mutation; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Rats; Receptors, Adrenergic, beta; Serine; Signal Transduction; src Homology Domains; Threonine; Tyrosine | 2015 |
Site-selective modification of peptides: From "customizable units" to novel α-aryl and α-alkyl glycine derivatives, and components of branched peptides.
Topics: Glycine; Peptides; Serine; Small Molecule Libraries; Substrate Specificity; Threonine | 2015 |
Phosphorylation of the cell division protein GpsB regulates PrkC kinase activity through a negative feedback loop in Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; Catalytic Domain; Cell Cycle Proteins; Cell Division; Feedback, Physiological; Phosphorylation; Protein Kinase C; Protein Structure, Tertiary; Serine; Threonine | 2015 |
The crystal structure of D-threonine aldolase from Alcaligenes xylosoxidans provides insight into a metal ion assisted PLP-dependent mechanism.
Topics: Acetaldehyde; Alanine Racemase; Alcaligenes; Aldehyde-Lyases; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Escherichia coli; Glycine; Manganese; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Multigene Family; Protein Conformation; Protein Structure, Tertiary; Protons; Pyridoxal Phosphate; Recombinant Proteins; Serine; Structure-Activity Relationship; Threonine | 2015 |
The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human Chemokines.
Topics: Amino Acid Sequence; Arrestins; beta-Arrestins; Cell Proliferation; Chemokine CXCL1; Chemokine CXCL10; DNA, Complementary; Endocytosis; Enzyme-Linked Immunosorbent Assay; HEK293 Cells; Humans; Interleukin-8; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Chemokine; Receptors, G-Protein-Coupled; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Type C Phospholipases; Viral Proteins | 2015 |
A quantitative study of the interactive effects of glycine and serine with threonine and choline on growth performance in broilers.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Choline; Diet; Dietary Supplements; Digestion; Glycine; Intestinal Mucosa; Male; Random Allocation; Serine; Threonine | 2015 |
Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasis.
Topics: Animals; Blood Vessels; Body Weight; Cytokines; Eicosanoids; Epoxide Hydrolases; Female; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Homeostasis; Hydroxyeicosatetraenoic Acids; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Sex Characteristics; Solubility; Superoxides; Threonine | 2015 |
C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor.
Topics: Animals; Arrestin; Binding Sites; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Receptors, G-Protein-Coupled; Retinal Rod Photoreceptor Cells; Rhodopsin; Serine; Threonine | 2015 |
Homologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivation.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Bacillus; Catalysis; Cell Proliferation; Computational Biology; Escherichia coli; Hydrolysis; Protein Biosynthesis; Protein Structure, Tertiary; Reproducibility of Results; RNA Editing; RNA, Transfer; Serine; Substrate Specificity; Temperature; Threonine | 2015 |
Phosphorylation site prediction in plants.
Topics: Binding Sites; Computational Biology; Databases, Protein; Internet; Machine Learning; Models, Statistical; Phosphorylation; Plant Proteins; Plants; Serine; Software; Threonine; Tyrosine | 2015 |
Drosophila DBT Autophosphorylation of Its C-Terminal Domain Antagonized by SPAG and Involved in UV-Induced Apoptosis.
Topics: Amino Acid Sequence; Animals; Apoptosis; Casein Kinase 1 epsilon; Cell Line; Circadian Rhythm; Drosophila melanogaster; Drosophila Proteins; Molecular Chaperones; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Threonine; Ultraviolet Rays | 2015 |
[Identifying phosphopeptide by searching a site annotated protein database].
Topics: Databases, Protein; Phosphopeptides; Phosphorylation; Proteomics; Reproducibility of Results; Serine; Threonine; Tyrosine | 2015 |
Useful agents against aflatoxin B1 - antibacterial azomethine and Mn(III) complexes involving L-Threonine, L-Serine, and L-Tyrosine.
Topics: Aflatoxin B1; Anti-Bacterial Agents; Antidotes; Azo Compounds; Bacteria; Female; Humans; Male; Manganese; Serine; Thiosemicarbazones; Threonine; Tyrosine | 2016 |
Cardiac Nitric Oxide Synthases and Na⁺/K⁺-ATPase in the Rat Model of Polycystic Ovary Syndrome Induced by Dihydrotestosterone.
Topics: Animals; Cell Membrane; Dihydrotestosterone; Disease Models, Animal; Down-Regulation; Female; Myocardium; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Polycystic Ovary Syndrome; Protein Processing, Post-Translational; Protein Transport; Random Allocation; Rats, Wistar; Serine; Sodium-Potassium-Exchanging ATPase; Threonine; Up-Regulation | 2015 |
Molecular mechanism of serine/threonine protein phosphatase 1 (PP1cα-PP1r7) in spermatogenesis of Toxocara canis.
Topics: Animals; Kinetochores; Male; Microtubules; Protein Phosphatase 1; Serine; Spermatogenesis; Threonine; Toxocara canis | 2015 |
Western Blotting Using PVDF Membranes and Its Downstream Applications.
Topics: Antibodies; Blotting, Western; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Horseradish Peroxidase; Hydrogen-Ion Concentration; Membranes, Artificial; Polyvinyls; Pyrrolidonecarboxylic Acid; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Serine; Threonine | 2015 |
Far infrared spectra of solid state L-serine, L-threonine, L-cysteine, and L-methionine in different protonation states.
Topics: Cysteine; Methionine; Models, Molecular; Molecular Conformation; Protons; Serine; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Threonine; Vibration; Water | 2015 |
Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry.
Topics: 14-3-3 Proteins; 3T3-L1 Cells; Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Enzyme Inhibitors; Epidermal Growth Factor; HEK293 Cells; Humans; Insulin; Mice; Phosphopeptides; Phosphoproteins; Phosphorylation; Proteomics; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Tandem Mass Spectrometry; Threonine; TOR Serine-Threonine Kinases | 2015 |
Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer.
Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Renal Cell; Catenins; Cell Transformation, Neoplastic; Delta Catenin; Female; Humans; Immunoenzyme Techniques; Immunoprecipitation; Kidney Neoplasms; Phosphoproteins; Phosphorylation; Protein Binding; Serine; Threonine; Tissue Array Analysis; Tumor Cells, Cultured; Tyrosine | 2015 |
Enzymatic Synthesis of Galactosylated Serine/Threonine Derivatives by β-Galactosidase from Escherichia coli.
Topics: beta-Galactosidase; Biocatalysis; Escherichia coli Proteins; Galactose; Molecular Docking Simulation; Serine; Threonine | 2015 |
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody.
Topics: Antibodies, Monoclonal; Antigens, Tumor-Associated, Carbohydrate; Glycosylation; Models, Molecular; Molecular Conformation; Mucin-1; Serine; Threonine | 2015 |
Physiologically relevant factors influence tau phosphorylation by leucine-rich repeat kinase 2.
Topics: Animals; Antibody Specificity; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Manganese; Mutation; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Serine; tau Proteins; Threonine | 2015 |
Potential Role of Glycogen Synthase Kinase-3β in Regulation of Myocardin Activity in Human Vascular Smooth Muscle Cells.
Topics: Actins; Calcium-Binding Proteins; Calponins; Cell Differentiation; Cell Line; Gene Expression Regulation; Gene Knockout Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Membrane Proteins; Microfilament Proteins; Muscle Proteins; Myocytes, Smooth Muscle; Nuclear Proteins; Phosphoproteins; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Recombinant Proteins; RNA, Small Interfering; Serine; Thiazoles; Threonine; Trans-Activators; Urea | 2016 |
Interleukin-2 Receptor β Thr-450 Phosphorylation Is a Positive Regulator for Receptor Complex Stability and Activation of Signaling Molecules.
Topics: Amino Acid Sequence; Cell Line; Gene Expression Regulation; Humans; Interleukin-2; Interleukin-2 Receptor beta Subunit; Janus Kinase 3; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Phosphorylation; Protein Phosphatase 1; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Serine; Signal Transduction; STAT5 Transcription Factor; Threonine; Tyrosine | 2015 |
Anks3 alters the sub-cellular localization of the Nek7 kinase.
Topics: Animals; Ankyrin Repeat; Carrier Proteins; Cytoplasm; HEK293 Cells; Humans; Kidney Diseases, Cystic; Mice; Molecular Weight; Multiprotein Complexes; Mutation; NIMA-Related Kinases; Nuclear Proteins; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Serine; Threonine; Transfection | 2015 |
Potential regulatory phosphorylation sites in a Medicago truncatula plasma membrane proton pump implicated during early symbiotic signaling in roots.
Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Cell Membrane; Cluster Analysis; Gene Expression Regulation, Enzymologic; Genetic Complementation Test; Host-Pathogen Interactions; Medicago truncatula; Molecular Sequence Data; Multigene Family; Mutation; Phosphorylation; Phylogeny; Plant Proteins; Plant Roots; Proton-Translocating ATPases; Rhizobium; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Serine; Signal Transduction; Symbiosis; Threonine | 2015 |
Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation.
Topics: Acetylglucosamine; Animals; Cell Line; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Glioma; Humans; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Macrophage Migration-Inhibitory Factors; Matrix Metalloproteinase 13; Mice, Nude; Microscopy, Fluorescence; Mutation; Phosphorylation; Protein Binding; RNA Interference; Serine; Survival Analysis; Threonine; Transplantation, Heterologous | 2015 |
Metabolomics strategy reveals therapeutical assessment of limonin on nonbacterial prostatitis.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Capsaicin; Disease Models, Animal; Glycerophospholipids; Glycine; Limonins; Male; Metabolomics; Prostatitis; Rats; Rats, Wistar; Serine; Threonine | 2015 |
Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown.
Topics: Anaphase; Animals; Binding Sites; Cell Cycle Proteins; Cell Line, Tumor; Centrosome; Cyclin-Dependent Kinase 2; Cyclins; Humans; Immunoblotting; Lung Neoplasms; Microtubule-Associated Proteins; Mutation; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Purines; RNA Interference; Roscovitine; Serine; Threonine; Ubiquitin Thiolesterase | 2015 |
A novel method for predicting post-translational modifications on serine and threonine sites by using site-modification network profiles.
Topics: Acetylation; Acetylglucosamine; Area Under Curve; Biochemistry; Phosphorylation; Protein Processing, Post-Translational; ROC Curve; Serine; Threonine | 2015 |
Atypical PKC phosphorylates microtubule affinity-regulating kinase 4 in vitro.
Topics: Adenosine Triphosphate; Cell Polarity; Humans; Hydrolysis; Mutation; Phosphorylation; Protein Engineering; Protein Interaction Domains and Motifs; Protein Kinase C; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Signal Transduction; Substrate Specificity; Threonine | 2015 |
Directed evolution of the Escherichia coli cAMP receptor protein at the cAMP pocket.
Topics: Allosteric Regulation; Codon; Crystallography, X-Ray; Cyclic AMP; Cyclic AMP Receptor Protein; Directed Molecular Evolution; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Gene Expression Regulation, Bacterial; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Serine; Threonine; Transcription, Genetic | 2015 |
Site-Specific Ser/Thr/Tyr Phosphoproteome of Sinorhizobium meliloti at Stationary Phase.
Topics: Bacterial Proteins; Computational Biology; Phosphoproteins; Phosphorylation; Proteome; Sequence Analysis, Protein; Serine; Sinorhizobium meliloti; Subcellular Fractions; Tandem Mass Spectrometry; Threonine; Tyrosine | 2015 |
O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities.
Topics: Acetylglucosamine; Escherichia coli; Genes, Reporter; HEK293 Cells; HeLa Cells; Humans; Luciferases; N-Acetylglucosaminyltransferases; Plasmids; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins; Serine; Signal Transduction; Sp2 Transcription Factor; Sp3 Transcription Factor; Sp4 Transcription Factor; Threonine; Transcription, Genetic | 2015 |
Arabidopsis Yak1 protein (AtYak1) is a dual specificity protein kinase.
Topics: Annexins; Arabidopsis; Arabidopsis Proteins; Electrophoresis, Gel, Two-Dimensional; Mutation; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Tyrosine | 2015 |
Specific Enrichment of Peptides with N-Terminal Serine/Threonine by a Solid-Phase Capture-Release Approach for Efficient Proteomics Analysis.
Topics: Chromatography, High Pressure Liquid; Humans; Peptides; Proteomics; Serine; Tandem Mass Spectrometry; Threonine; Trypsin | 2015 |
Stereoselective recognition of the Ac-Glu-Tyr-OH dipeptide by pseudopeptidic cages.
Topics: Amides; Cyclohexanes; Dipeptides; Glutamine; Models, Biological; Molecular Structure; Serine; Stereoisomerism; Threonine; Tyrosine | 2015 |
The Sensor Histidine Kinases AHK2 and AHK3 Proceed into Multiple Serine/Threonine/Tyrosine Phosphorylation Pathways in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Histidine Kinase; Phosphorylation; Protein Kinases; Serine; Threonine; Tyrosine | 2016 |
Solid-phase synthesis and in vitro biological activity of a Thr4→Ser4 analog of daptomycin.
Topics: Anti-Bacterial Agents; Bacillaceae; Calcium; Daptomycin; Microbial Sensitivity Tests; Molecular Structure; Serine; Solid-Phase Synthesis Techniques; Threonine | 2015 |
Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone.
Topics: Animals; Cyclic GMP; Epiregulin; Female; Granulosa Cells; Guanylate Cyclase; Luteinizing Hormone; Meiosis; Mice; Oocytes; Phosphorylation; Receptors, Atrial Natriuretic Factor; Serine; Sheep; Threonine | 2016 |
Theoretical investigations on the interactions of glucokinase regulatory protein with fructose phosphates.
Topics: Adaptor Proteins, Signal Transducing; Catalytic Domain; Fructosephosphates; Humans; Lysine; Models, Chemical; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Domains; Serine; Threonine | 2016 |
Obg-like ATPase 1 regulates global protein serine/threonine phosphorylation in cancer cells by suppressing the GSK3β-inhibitor 2-PP1 positive feedback loop.
Topics: Adenosine Triphosphatases; Animals; Blotting, Western; Colorectal Neoplasms; Feedback, Physiological; Female; Glycogen Synthase Kinase 3 beta; GTP-Binding Proteins; Humans; Immunoenzyme Techniques; Mice; Mice, SCID; Ovarian Neoplasms; Phosphoproteins; Phosphorylation; Protein Phosphatase 1; Proteins; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Involvement of cAMP-dependent unique signaling cascades in the decrease of serine/threonine-phosphorylated proteins in boar sperm head.
Topics: Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Male; Phosphorylation; Serine; Signal Transduction; Sperm Head; Swine; Threonine | 2016 |
Spontaneous cleavage of proteins at serine and threonine is facilitated by zinc.
Topics: alpha-Crystallin B Chain; Humans; Longevity; Nuclear Magnetic Resonance, Biomolecular; Proteomics; Recombinant Proteins; Serine; Threonine; Zinc | 2016 |
Effects of phosphorylation on the intrinsic propensity of backbone conformations of serine/threonine.
Topics: Amino Acid Sequence; Molecular Dynamics Simulation; Oligopeptides; Peptides; Phosphorylation; Protein Conformation; Serine; Threonine | 2016 |
Phosphorylation Increases Persistence Length and End-to-End Distance of a Segment of Tau Protein.
Topics: Amino Acid Sequence; Humans; Molecular Sequence Data; Peptides; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Serine; tau Proteins; Threonine | 2016 |
Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Binding Sites, Antibody; Crystallography, X-Ray; Epitope Mapping; Epitopes; Gene Expression; HEK293 Cells; Humans; Immunoglobulin Fab Fragments; Models, Molecular; Phosphopeptides; Phosphorylation; Protein Binding; Protein Folding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Recombinant Proteins; Serine; tau Proteins; Threonine | 2016 |
Structural and functional characterization of phosphomimetic mutants of cytochrome c at threonine 28 and serine 47.
Topics: Cardiolipins; Caspases; Cytochromes c; Electron Transport; Enzyme Stability; Mutation; Serine; Threonine | 2016 |
A Human Disease-causing Point Mutation in Mitochondrial Threonyl-tRNA Synthetase Induces Both Structural and Functional Defects.
Topics: Adenosine Monophosphate; Alternative Splicing; Amino Acid Sequence; Enzyme Activation; Enzyme Stability; Genetic Complementation Test; HEK293 Cells; Humans; Isoenzymes; Kinetics; Mitochondria; Mitochondrial Encephalomyopathies; Models, Molecular; Molecular Sequence Data; Point Mutation; Protein Multimerization; Protein Transport; Saccharomyces cerevisiae; Serine; Threonine; Threonine-tRNA Ligase; Transfer RNA Aminoacylation | 2016 |
Preventing N- and O-formylation of proteins when incubated in concentrated formic acid.
Topics: Escherichia coli Proteins; Formates; Histones; Humans; Peptide Fragments; Proteomics; Serine; Solubility; Tandem Mass Spectrometry; Threonine | 2016 |
Kinetic Study of Laboratory Mutants of NDM-1 Metallo-β-Lactamase and the Importance of an Isoleucine at Position 35.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Biocatalysis; Catalytic Domain; Cephalosporins; Cloning, Molecular; Escherichia coli; Gene Expression; Isoleucine; Kinetics; Models, Molecular; Mutation; Protein Structure, Secondary; Recombinant Proteins; Serine; Threonine | 2016 |
Myosin di-phosphorylation and peripheral actin bundle formation as initial events during endothelial barrier disruption.
Topics: Actins; Animals; Aorta; Calcium; Capillary Permeability; Electric Impedance; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Mutation; Myosin Light Chains; Myosins; Phosphorylation; Primary Cell Culture; Protein Kinase Inhibitors; Receptor, PAR-1; rho-Associated Kinases; Serine; Swine; Threonine; Thrombin | 2016 |
Ablation of eNOS does not promote adipose tissue inflammation.
Topics: Adipose Tissue, Brown; Adiposity; Animals; Diet, High-Fat; Disease Models, Animal; Genetic Predisposition to Disease; Inflammation Mediators; Insulin Resistance; Intra-Abdominal Fat; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Panniculitis; Phenotype; Phosphorylation; Serine; Signal Transduction; Threonine | 2016 |
Distinct Phosphorylation Clusters Determine the Signaling Outcome of Free Fatty Acid Receptor 4/G Protein-Coupled Receptor 120.
Topics: Amino Acid Substitution; Animals; Arrestins; Bacterial Proteins; Cell Membrane; CHO Cells; Cricetulus; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gq-G11; HEK293 Cells; Humans; Luminescent Proteins; MAP Kinase Signaling System; Membrane Transport Modulators; Mice; Mutation; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Serine; Threonine | 2016 |
Cytotoxicity studies of water soluble coordination compounds with a [Mo2O2S2](2+) core.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Coordination Complexes; Cysteine; HT29 Cells; Humans; Inhibitory Concentration 50; Ligands; MCF-7 Cells; Metals, Alkali; Molybdenum; Organometallic Compounds; Serine; Solubility; Structure-Activity Relationship; Sulfur; Threonine; Water | 2016 |
NEK1 mutations in familial amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Brain; Cohort Studies; Family Health; Female; Gene Frequency; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; NIMA-Related Kinase 1; Respiratory Insufficiency; Serine; Threonine | 2016 |
Identification of Novel Variants in the PVRL1 Gene in Patients With Nonsyndromic Cleft Lip With or Without Cleft Palate.
Topics: Amino Acid Substitution; Case-Control Studies; Cell Adhesion Molecules; Child; Child, Preschool; Cleft Lip; Cleft Palate; DNA Mutational Analysis; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Nectins; Polymorphism, Single Nucleotide; Serine; Threonine; Turkey | 2016 |
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Topics: Aspartic Acid; Autolysis; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Lysine; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Protein Precursors; Proteolysis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine | 2016 |
p38β Mitogen-Activated Protein Kinase Modulates Its Own Basal Activity by Autophosphorylation of the Activating Residue Thr180 and the Inhibitory Residues Thr241 and Ser261.
Topics: Animals; Bone and Bones; Catalytic Domain; Cell Differentiation; Cell Line; Fibroblasts; HEK293 Cells; Humans; Mice; Mitogen-Activated Protein Kinase 11; Muscles; Phosphorylation; Serine; Threonine | 2016 |
Basal levels of AMPA receptor GluA1 subunit phosphorylation at threonine 840 and serine 845 in hippocampal neurons.
Topics: Animals; Hippocampus; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Neurons; Protein Subunits; Receptors, AMPA; Serine; Threonine | 2016 |
Effects of straight alkyl chain, extra hydroxylated alkyl chain and branched chain amino acids on gastric emptying evaluated using a non-invasive breath test in conscious rats.
Topics: Acetic Acid; Administration, Oral; Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Breath Tests; Consciousness; Gastric Emptying; Glycine; Isoleucine; Leucine; Male; Rats, Sprague-Dawley; Serine; Threonine; Valine | 2016 |
Identification of Connexin43 Phosphorylation and S-Nitrosylation in Cultured Primary Vascular Cells.
Topics: Biotin; Blotting, Western; Cells, Cultured; Connexin 43; Cysteine; Fluorescent Antibody Technique; Human Umbilical Vein Endothelial Cells; Humans; Phosphorylation; Primary Cell Culture; Protein Processing, Post-Translational; S-Nitrosothiols; Serine; Threonine; Tyrosine | 2016 |
Serine and threonine residues of plant STN7 kinase are differentially phosphorylated upon changing light conditions and specifically influence the activity and stability of the kinase.
Topics: Arabidopsis; Arabidopsis Proteins; Light; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine | 2016 |
Development of Optimized AAV Serotype Vectors for High-Efficiency Transduction at Further Reduced Doses.
Topics: Capsid; Dependovirus; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Genome, Human; HEK293 Cells; Humans; Lysine; Serine; Serogroup; Threonine; Transduction, Genetic; Tyrosine | 2016 |
Increases of SET level and translocation are correlated with tau hyperphosphorylation at ser202/thr205 in CA1 of Ts65Dn mice.
Topics: Amyloid beta-Protein Precursor; Animals; Brain; CA1 Region, Hippocampal; Cytoplasm; Disease Models, Animal; DNA-Binding Proteins; Down Syndrome; Gene Expression; Histone Chaperones; Male; Mice; Mice, Inbred Strains; Molecular Targeted Therapy; Oncogene Proteins; Phosphorylation; Protein Phosphatase 2; Protein Transport; Serine; Sirolimus; tau Proteins; Threonine | 2016 |
Topics: Adolescent; Adult; Age Factors; Aged; Amino Acid Substitution; Anemia, Aplastic; Athletes; Athletic Performance; Bone Marrow Transplantation; Carcinoma, Non-Small-Cell Lung; Catalytic Domain; Cell Count; Child; Child, Preschool; Escherichia coli; Female; Gene Expression; Graft Survival; Graft vs Host Disease; Histocompatibility Testing; Humans; Hydrogen Bonding; Immunosuppression Therapy; Inosine Monophosphate; Integrin alphaVbeta3; Kinetics; Knee Joint; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinal Neoplasms; Middle Aged; Molecular Dynamics Simulation; Muscle, Skeletal; Mutation; Organotechnetium Compounds; Pentosyltransferases; Peptides, Cyclic; Phenylalanine; Plasmodium falciparum; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protozoan Proteins; Radiopharmaceuticals; Recombinant Proteins; Running; Sensitivity and Specificity; Serine; Siblings; Single Photon Emission Computed Tomography Computed Tomography; Soccer; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Threonine; Time Factors; Torque; Treatment Outcome; Tryptophan; Tyrosine; Young Adult | 2016 |
PIN1 in hepatocellular carcinoma is associated with TP53 gene status.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; NIMA-Interacting Peptidylprolyl Isomerase; Phosphorylation; Serine; Threonine; Tumor Suppressor Protein p53 | 2016 |
Position 97 of HLA-B, a residue implicated in pathogenesis of ankylosing spondylitis, plays a key role in cell surface free heavy chain expression.
Topics: Aminopeptidases; Antigens, Surface; Asparagine; ATP-Binding Cassette Transporters; beta 2-Microglobulin; Flow Cytometry; HeLa Cells; HLA-B27 Antigen; HLA-B51 Antigen; HLA-B7 Antigen; Humans; Membrane Transport Proteins; Minor Histocompatibility Antigens; Mutation; Serine; Spondylitis, Ankylosing; Threonine; Transfection; Valine | 2017 |
Activation and inhibition of Snf1 kinase activity by phosphorylation within the activation loop.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cloning, Molecular; Conserved Sequence; Escherichia coli; Gene Expression; Models, Molecular; Mutation; Phosphoproteins; Phosphorylation; Protein Domains; Protein Serine-Threonine Kinases; Protein Structure, Secondary; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Alignment; Serine; Threonine | 2016 |
Elevated O-GlcNAcylation promotes gastric cancer cells proliferation by modulating cell cycle related proteins and ERK 1/2 signaling.
Topics: Acetylglucosamine; Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 2; Down-Regulation; Female; Gene Knockdown Techniques; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Acetylglucosaminyltransferases; Phosphorylation; Protein Processing, Post-Translational; RNA Interference; RNA, Small Interfering; Serine; Stomach Neoplasms; Threonine; Up-Regulation; Xenograft Model Antitumor Assays | 2016 |
Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes.
Topics: Animals; Calcineurin; Cells, Cultured; Mice; Microfilament Proteins; Phosphorylation; Podocytes; Receptor Cross-Talk; rhoA GTP-Binding Protein; Serine; Signal Transduction; Threonine; Tyrosine | 2017 |
Podocyte biology: Dynamic control of actin remodelling.
Topics: Actins; Phosphorylation; Podocytes; Serine; Threonine; Tyrosine | 2016 |
Flagellin FliC Phosphorylation Affects Type 2 Protease Secretion and Biofilm Dispersal in Pseudomonas aeruginosa PAO1.
Topics: Adaptation, Physiological; Bacterial Proteins; Biofilms; Flagellin; Gene Expression Regulation, Bacterial; Mutation; Peptide Hydrolases; Phosphorylation; Proteomics; Pseudomonas aeruginosa; Serine; Threonine; Type II Secretion Systems | 2016 |
Two novel pyrrolooxazole pigments formed by the Maillard reaction between glucose and threonine or serine.
Topics: Glucose; Maillard Reaction; Oxazoles; Pigments, Biological; Serine; Threonine | 2017 |
An archaeal ADP-dependent serine kinase involved in cysteine biosynthesis and serine metabolism.
Topics: Archaeal Proteins; Cysteine; Gene Expression Regulation, Archaeal; Gene Expression Regulation, Enzymologic; Glycine; Protein Serine-Threonine Kinases; Serine; Thermococcus; Threonine | 2016 |
Tracking protons from respiratory chain complexes to ATP synthase c-subunit: The critical role of serine and threonine residues.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Bacterial Proton-Translocating ATPases; Escherichia coli; Escherichia coli Proteins; Humans; Hydrogen Bonding; Models, Molecular; Protons; Sequence Alignment; Serine; Threonine; X-Ray Diffraction | 2017 |
CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes.
Topics: Active Transport, Cell Nucleus; Amino Acid Substitution; Animals; Cdh1 Proteins; Cell Differentiation; Cell Nucleus; Cells, Cultured; DNA Damage; Down-Regulation; E2F1 Transcription Factor; Keratinocytes; Lysine; Mice; Protein Processing, Post-Translational; Proteolysis; Serine; Threonine | 2017 |
Estrogen Protects the Female Heart from Ischemia/Reperfusion Injury through Manganese Superoxide Dismutase Phosphorylation by Mitochondrial p38β at Threonine 79 and Serine 106.
Topics: Animals; Estradiol; Female; Mitochondria, Heart; Myocardial Reperfusion Injury; Ovariectomy; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Superoxide Dismutase; Threonine | 2016 |
Chemical Synthesis of HMGA1a Proteins with Post-translational Modifications via Ser/Thr Ligation.
Topics: Amino Acid Sequence; HMGA1a Protein; Molecular Structure; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Serine; Solid-Phase Synthesis Techniques; Threonine | 2016 |
Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity.
Topics: Allosteric Regulation; Archaeal Proteins; Binding Sites; Biocatalysis; Biosynthetic Pathways; Crystallography, X-Ray; Glycerophosphates; Indoles; Kinetics; Models, Molecular; Molecular Structure; Protein Binding; Protein Domains; Protein Subunits; Pyrococcus furiosus; Serine; Spectrophotometry; Substrate Specificity; Threonine; Tryptophan; Tryptophan Synthase | 2016 |
Bisulfite Sequencing with Daphnia Highlights a Role for Epigenetics in Regulating Stress Response to Microcystis through Preferential Differential Methylation of Serine and Threonine Amino Acids.
Topics: Amino Acids; Animals; Daphnia; Microcystis; Serine; Threonine | 2017 |
Post-translational Modifications of Trypanosoma cruzi Canonical and Variant Histones.
Topics: Acetylation; Acylation; Epigenesis, Genetic; Histone Code; Histones; Lysine; Protein Processing, Post-Translational; Protozoan Proteins; Serine; Threonine; Trypanosoma cruzi | 2017 |
PP2A
Topics: Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinases; Phosphorylation; Protein Phosphatase 2; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine; Transcription Factors | 2017 |
Metagenomics approach to the study of the gut microbiome structure and function in zebrafish Danio rerio fed with gluten formulated diet.
Topics: Animals; Bacteria; Bile Acids and Salts; Biodiversity; Computational Biology; Diet; DNA, Bacterial; Ecosystem; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Tract; Genes, Bacterial; Glutens; Glycine; Metagenomics; Microbial Consortia; Models, Animal; Phylogeny; RNA, Ribosomal, 16S; Serine; Threonine; Vitamin B 12; Zebrafish | 2017 |
Stoichiometry and structure of a lantibiotic maturation complex.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genetic Vectors; Intramolecular Lyases; Lactococcus lactis; Membrane Proteins; Models, Molecular; Nisin; Peptides; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins; Serine; Structural Homology, Protein; Substrate Specificity; Threonine | 2017 |
Unambiguous Identification of Serine and Threonine Pyrophosphorylation Using Neutral-Loss-Triggered Electron-Transfer/Higher-Energy Collision Dissociation.
Topics: Chromatography, Liquid; Electron Transport; Phosphopeptides; Phosphorylation; Serine; Tandem Mass Spectrometry; Threonine | 2017 |
Histone and DNA methylation control by H3 serine 10/threonine 11 phosphorylation in the mouse zygote.
Topics: Animals; Chromatin; CpG Islands; DNA Methylation; Histones; Mice; Mutagenesis, Site-Directed; Phosphorylation; Sequence Analysis, DNA; Serine; Threonine; Zygote | 2017 |
Semi-microbiological synthesis of an active lysinoalanine-bridged analog of glucagon-like-peptide-1.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Glucagon-Like Peptide 1; Hydro-Lyases; Lactococcus lactis; Lysinoalanine; Membrane Proteins; Membrane Transport Proteins; Protein Processing, Post-Translational; SEC Translocation Channels; Serine; Substrate Specificity; Threonine | 2017 |
Molecular dynamics simulations elucidate conformational selection and induced fit mechanisms in the binding of PD-1 and PD-L1.
Topics: B7-H1 Antigen; Crystallography, X-Ray; Humans; Hydrogen Bonding; Models, Molecular; Molecular Dynamics Simulation; Programmed Cell Death 1 Receptor; Protein Binding; Protein Conformation; Serine; Threonine | 2017 |
Different phosphoisoforms of RNA polymerase II engage the Rtt103 termination factor in a structurally analogous manner.
Topics: Amino Acid Sequence; Peptide Termination Factors; Phosphorylation; Protein Domains; Protein Isoforms; RNA Polymerase II; RNA, Small Nucleolar; RNA, Small Untranslated; RNA, Untranslated; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Transcription Factors; Transcription, Genetic | 2017 |
Structural insight into recognition of phosphorylated threonine-4 of RNA polymerase II C-terminal domain by Rtt103p.
Topics: Phosphorylation; Protein Binding; Protein Kinases; Protein Structure, Tertiary; Proteolysis; RNA Polymerase II; Saccharomyces cerevisiae Proteins; Serine; Threonine; Transcription Factors; Transcription, Genetic; Tyrosine | 2017 |
Synthesis and structure-activity relationship of teixobactin analogues via convergent Ser ligation.
Topics: Anti-Bacterial Agents; Depsipeptides; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Serine; Staphylococcus aureus; Structure-Activity Relationship; Threonine | 2017 |
Site-specific phosphorylation of casein kinase 1 δ (CK1δ) regulates its activity towards the circadian regulator PER2.
Topics: Binding Sites; Casein Kinase Idelta; Cell Cycle; Gene Expression Regulation; HEK293 Cells; Humans; Mutation; Period Circadian Proteins; Phosphorylation; Protein Stability; Serine; Signal Transduction; Threonine | 2017 |
Characterization and application studies of ProxyPhos, a chemosensor for the detection of proximally phosphorylated peptides and proteins in aqueous solutions.
Topics: Fluorescent Dyes; Peptides; Phosphorylation; Proteins; Serine; Spectrometry, Fluorescence; Threonine; Tyrosine | 2017 |
Quantitative chiral analysis of amino acids in solution using enantiomer-selective photodissociation of cold gas-phase tryptophan via chiral recognition.
Topics: Alanine; Amino Acids; Serine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Threonine; Tryptophan | 2017 |
The Sulfur-Linked Analogue of O-GlcNAc (S-GlcNAc) Is an Enzymatically Stable and Reasonable Structural Surrogate for O-GlcNAc at the Peptide and Protein Levels.
Topics: Acetylglucosamine; alpha-Synuclein; Animals; beta-N-Acetylhexosaminidases; Circular Dichroism; Computational Biology; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Folding; Protein Processing, Post-Translational; Protein Stability; Recombinant Proteins; Serine; Substrate Specificity; Threonine | 2017 |
Autophosphorylation Affects Substrate-Binding Affinity of Tobacco Ca
Topics: 14-3-3 Proteins; Gibberellins; Mutation; Nicotiana; Phosphorylation; Plant Proteins; Plants, Genetically Modified; Protein Binding; Protein Kinases; Protein Multimerization; Serine; Substrate Specificity; Threonine; Triazoles | 2017 |
Deciphering the role of the signal- and Sty1 kinase-dependent phosphorylation of the stress-responsive transcription factor Atf1 on gene activation.
Topics: Activating Transcription Factor 1; Amino Acid Substitution; Basic-Leucine Zipper Transcription Factors; Gene Deletion; Gene Expression Regulation, Fungal; MAP Kinase Signaling System; Microbial Viability; Mitogen-Activated Protein Kinases; Models, Molecular; Mutation; Oxidative Stress; Pancreatitis-Associated Proteins; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Protein Conformation; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Stability; Recombinant Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Serine; Threonine; Transcriptional Activation | 2017 |
iMulti-HumPhos: a multi-label classifier for identifying human phosphorylated proteins using multiple kernel learning based support vector machines.
Topics: Benchmarking; Computational Biology; Datasets as Topic; Humans; Internet; Phosphorylation; Protein Processing, Post-Translational; Proteins; Serine; Software; Support Vector Machine; Threonine; Tyrosine | 2017 |
The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites.
Topics: Amino Acid Substitution; Enzyme Stability; Gene Expression Regulation, Fungal; Mechanistic Target of Rapamycin Complex 2; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Stress, Physiological; Threonine | 2017 |
Lead exposure and tau hyperphosphorylation: An in vitro study.
Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Cyclin-Dependent Kinase 5; Densitometry; Dose-Response Relationship, Drug; Humans; Lead; Nerve Tissue Proteins; Neuroblastoma; Neurons; Phosphorylation; Serine; tau Proteins; Threonine; Time Factors; Tretinoin | 2017 |
Phosphorylation-dependent signaling controls degradation of DNA mismatch repair protein PMS2.
Topics: Blotting, Western; Enzyme Inhibitors; HEK293 Cells; Humans; Marine Toxins; Mismatch Repair Endonuclease PMS2; Mutation; MutL Protein Homolog 1; MutL Proteins; Niacinamide; Oxazoles; Phenylurea Compounds; Phosphorylation; Proteolysis; Serine; Signal Transduction; Sorafenib; Threonine | 2017 |
CDK1-mediated mitotic phosphorylation of PBK is involved in cytokinesis and inhibits its oncogenic activity.
Topics: Carcinogenesis; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Cytokinesis; HEK293 Cells; HeLa Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Mitosis; Mutation; Phosphorylation; Serine; Threonine | 2017 |
Identification of the Tau phosphorylation pattern that drives its aggregation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Humans; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Models, Molecular; Peptide Fragments; Phosphorylation; Protein Aggregation, Pathological; Protein Domains; Rats, Sprague-Dawley; Serine; tau Proteins; Threonine | 2017 |
Histone phosphorylation by TRPM6's cleaved kinase attenuates adjacent arginine methylation to regulate gene expression.
Topics: Arginine; Cell Line; Gene Expression Regulation; Histones; Humans; Methylation; Phosphorylation; Protein Domains; Serine; Threonine; TRPM Cation Channels | 2017 |
Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation.
Topics: Acetylglucosamine; Amino Acid Motifs; Amino Acid Sequence; Glycosylation; Humans; Mass Spectrometry; N-Acetylglucosaminyltransferases; Phosphorylation; Proline; Protein Processing, Post-Translational; Proteins; Proteolysis; Serine; Signal Transduction; Threonine | 2017 |
Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation.
Topics: Cell Cycle Proteins; Checkpoint Kinase 2; DNA Damage; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Phosphothreonine; Protein Domains; Protein Multimerization; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae Proteins; Scattering, Small Angle; Serine; Threonine | 2017 |
FPD: A comprehensive phosphorylation database in fungi.
Topics: Animals; Databases, Factual; Fungal Proteins; Fungi; Humans; Phosphorylation; Plants; Protein Processing, Post-Translational; Serine; Threonine; Tyrosine | 2017 |
Prediction of phosphorylation sites based on Krawtchouk image moments.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Area Under Curve; Computational Biology; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; ROC Curve; Serine; Support Vector Machine; Threonine; Tyrosine | 2017 |
Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Topics: beta-N-Acetylhexosaminidases; Crystallography, X-Ray; Glycopeptides; Humans; Models, Molecular; Protein Conformation; Serine; Substrate Specificity; Threonine | 2017 |
Metal-Free, Site-Selective Peptide Modification by Conversion of "Customizable" Units into β-Substituted Dehydroamino Acids.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Biochemical Phenomena; Organophosphonates; Peptides; Protein Binding; Protein Conformation; Serine; Threonine | 2018 |
Subarachnoid hemorrhage induces neuronal nitric oxide synthase phosphorylation at Ser
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dentate Gyrus; Male; Neurons; Nitric Oxide Synthase Type I; Phosphorylation; Rats, Sprague-Dawley; Serine; Subarachnoid Hemorrhage; Threonine | 2018 |
Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis.
Topics: Amino Acid Sequence; Amino Acid Substitution; CDC2 Protein Kinase; Cdc20 Proteins; Cdh1 Proteins; Chromosomal Proteins, Non-Histone; Conserved Sequence; HeLa Cells; Humans; Kinetics; Mitosis; Phosphorylation; Protein Phosphatase 2; Recombinant Proteins; RNA Interference; Serine; Threonine | 2017 |
Regulation of transcription elongation in response to osmostress.
Topics: Gene Expression Regulation, Fungal; Mitogen-Activated Protein Kinases; Nuclear Proteins; Osmotic Pressure; Protein Binding; RNA Polymerase II; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Transcription, Genetic; Transcriptional Elongation Factors | 2017 |
Long-term Helicobacter pylori infection does not induce tauopathy and memory impairment in SD rats.
Topics: Animals; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Female; Gene Expression Regulation; Helicobacter Infections; Helicobacter pylori; Hippocampus; Maze Learning; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Stomach; tau Proteins; Threonine | 2017 |
RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases.
Topics: Cell Line, Tumor; Cell Movement; Enzyme Activation; HEK293 Cells; Humans; Mutation; Phosphorylation; rho GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Serine; Signal Transduction; Threonine | 2018 |
Filling gaps in bacterial amino acid biosynthesis pathways with high-throughput genetics.
Topics: Amino Acids; Bacteria; Bacterial Proteins; Heterotrophic Processes; High-Throughput Nucleotide Sequencing; Histidine; Methionine; Sequence Analysis, DNA; Serine; Threonine | 2018 |
Discrepancy Between Low Levels of mTOR Activity and High Levels of P-S6 in Primary Central Nervous System Lymphoma May Be Explained by PAS Domain-Containing Serine/Threonine-Protein Kinase-Mediated Phosphorylation.
Topics: Cell Line, Tumor; Central Nervous System Neoplasms; Chi-Square Distribution; Female; Humans; Lymphoma; Male; Phosphorylation; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Threonine; TOR Serine-Threonine Kinases | 2018 |
p.Val452Ile mutation of the SLC25A13 gene in a Turkish patient with citrin deficiency.
Topics: Child; Citrulline; Citrullinemia; High-Throughput Nucleotide Sequencing; Humans; Infant; Infant Formula; Jaundice, Neonatal; Male; Mitochondrial Membrane Transport Proteins; Mutation, Missense; Serine; Threonine; Turkey | 2017 |
Computational Prediction of Protein O-GlcNAc Modification.
Topics: Acetylglucosamine; Algorithms; Animals; Computational Biology; Datasets as Topic; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Protein Structure, Secondary; Serine; Threonine | 2018 |
The Phosphorylation of CCR6 on Distinct Ser/Thr Residues in the Carboxyl Terminus Differentially Regulates Biological Function.
Topics: Actins; beta-Arrestin 1; beta-Arrestin 2; Humans; Jurkat Cells; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Domains; Receptor Aggregation; Receptors, CCR6; Serine; Signal Transduction; Threonine | 2018 |
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.
Topics: Adaptor Proteins, Signal Transducing; Biocatalysis; Cell Line, Tumor; Crystallography, X-Ray; Cysteine; Esterification; HEK293 Cells; Humans; Lysine; Models, Molecular; Protein Domains; Proteomics; Serine; Substrate Specificity; Threonine; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2018 |
Phosphorylated nucleolar Tau protein is related to the neuronal in vitro differentiation.
Topics: Alternative Splicing; Biomarkers; Cell Differentiation; Cell Line, Tumor; Cell Nucleolus; Dactinomycin; DNA, Ribosomal; Epitopes; Fluorescent Antibody Technique; Humans; Lymphocytes; Mitosis; Neurons; Phosphorylation; Phytohemagglutinins; Pol1 Transcription Initiation Complex Proteins; Protein Isoforms; Serine; tau Proteins; Threonine; Tretinoin | 2018 |
Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition.
Topics: Adenosine Triphosphate; Bacterial Proteins; Binding Sites; Catalytic Domain; Histidine Kinase; Molecular Docking Simulation; Protein Kinase Inhibitors; Serine; Thermotoga maritima; Threonine | 2018 |
Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy.
Topics: A549 Cells; Adenylate Kinase; Amino Acid Sequence; Animals; Autophagy; bcl-X Protein; Beclin-1; Catalysis; Death-Associated Protein Kinases; Dimerization; HCT116 Cells; HEK293 Cells; Humans; Male; Mice; Mutation; Phosphorylation; Sequence Homology, Amino Acid; Serine; Stress, Physiological; Threonine | 2018 |
Suppressive effects of the peel of Citrus kawachiensis (Kawachi Bankan) on astroglial activation, tau phosphorylation, and inhibition of neurogenesis in the hippocampus of type 2 diabetic db/db mice.
Topics: Animals; Blood Glucose; Citrus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hippocampus; Hyperglycemia; Male; Mice, Inbred C57BL; Microglia; Neurogenesis; Neuroprotective Agents; Phosphorylation; Plant Structures; Powders; Serine; Streptozocin; tau Proteins; Threonine | 2018 |
Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation.
Topics: Cyclin-Dependent Kinase 9; Enzyme Activation; HIV-1; HSP90 Heat-Shock Proteins; Humans; Jurkat Cells; Phosphorylation; Positive Transcriptional Elongation Factor B; Protein Binding; Serine; tat Gene Products, Human Immunodeficiency Virus; Threonine; Virus Activation | 2018 |
Identification and efficacy of glycine, serine and threonine metabolism in potentiating kanamycin-mediated killing of Edwardsiella piscicida.
Topics: Amino Acids; Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Synergism; Edwardsiella; Glucose; Glycine; Kanamycin; Serine; Threonine | 2018 |
Multiple phosphorylation sites on γ-tubulin are essential and contribute to the biogenesis of basal bodies in Tetrahymena.
Topics: Amino Acid Sequence; Animals; Basal Bodies; Centrioles; Cilia; Genome; Microtubules; Phosphorylation; Serine; Tetrahymena thermophila; Threonine; Tubulin | 2018 |
Genetic code expansion and live cell imaging reveal that Thr-308 phosphorylation is irreplaceable and sufficient for Akt1 activity.
Topics: Cells, Cultured; Crystallography, X-Ray; Genetic Code; Humans; Molecular Imaging; Mutation; Phosphorylation; Protein Conformation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2018 |
Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; GTP-Binding Protein alpha Subunits; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Nuclear Proteins; Phosphorylation; Protein Conformation; Protein Folding; Rats; Serine; Signal Transduction; Threonine | 2018 |
Hydrazide functionalized magnetic nanoparticles for specific extraction of N-terminal serine and threonine peptides.
Topics: Chromatography, High Pressure Liquid; Hydrazones; Magnetite Nanoparticles; Peptides; Serine; Solid Phase Extraction; Threonine | 2018 |
Evaluation of functionality for serine and threonine phosphorylation with different evolutionary ages in human and mouse.
Topics: Animals; Evolution, Molecular; Humans; Mice; Phosphorylation; Serine; Threonine | 2018 |
Quantification of thioether-linked glutathione modifications in human lens proteins.
Topics: Adolescent; Alanine; Aminobutyrates; Cataract; Cellular Senescence; Chromatography, Liquid; Crystallins; Cysteine; Glutathione; Humans; Lens, Crystalline; Middle Aged; Protein Processing, Post-Translational; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Tissue Donors; Young Adult | 2018 |
Phosphorylation of different tau sites during progression of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Disease Progression; Female; Humans; Male; Middle Aged; Phosphorylation; Psychiatric Status Rating Scales; Serine; Statistics, Nonparametric; tau Proteins; Threonine; Tyrosine | 2018 |
Serine/Threonine Ligation: Origin, Mechanistic Aspects, and Applications.
Topics: Aldehydes; Esters; Models, Chemical; Peptides, Cyclic; Proteins; Serine; Threonine | 2018 |
Glyphosate Resistance in Tridax procumbens via a Novel EPSPS Thr-102-Ser Substitution.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Amino Acid Motifs; Amino Acid Substitution; Asteraceae; Glycine; Glyphosate; Herbicide Resistance; Herbicides; Mutation, Missense; Phosphoenolpyruvate; Plant Proteins; Serine; Threonine | 2018 |
Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis.
Topics: Crystallography, X-Ray; Enzyme Activation; HCT116 Cells; Humans; Phosphorylation; Pleckstrin Homology Domains; Protein Binding; Protein Biosynthesis; Protein Conformation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine | 2018 |
Rhodobacterales use a unique L-threonine kinase for the assembly of the nucleotide loop of coenzyme B
Topics: Amino Acid Sequence; Bacterial Proteins; Cobalt; Cobamides; Nucleotides; Phylogeny; Protein Serine-Threonine Kinases; Rhodobacter capsulatus; Rhodobacter sphaeroides; Salmonella enterica; Serine; Threonine | 2018 |
[Effects of serine/threonine-protein kinase B-Raf-activated long-chain non-coding RNA on apoptosis and autophagy in thyroid carcinoma cells].
Topics: Apoptosis; Autophagy; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Proto-Oncogene Proteins B-raf; RNA, Long Noncoding; Serine; Threonine; Thyroid Gland; Thyroid Neoplasms | 2018 |
Protein Chemical Approaches to Understanding PTEN Lipid Phosphatase Regulation.
Topics: Animals; Cell Membrane; Enzyme Assays; Mutation; Phosphorylation; Protein Domains; Protein Stability; PTEN Phosphohydrolase; Recombinant Fusion Proteins; Serine; Sf9 Cells; Spodoptera; Structure-Activity Relationship; Threonine; Ubiquitination | 2018 |
Role of Ser65, His148 and Thr203 in the Organic Solvent-dependent Spectral Shift in Green Fluorescent Protein.
Topics: Green Fluorescent Proteins; Histidine; Organic Chemicals; Serine; Solvents; Threonine | 2019 |
Regulation of the Natriuretic Peptide Receptor 2 (Npr2) by Phosphorylation of Juxtamembrane Serine and Threonine Residues Is Essential for Bifurcation of Sensory Axons.
Topics: Animals; Axons; Female; Ganglia, Sensory; Ganglia, Spinal; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphorylation; Pregnancy; Receptors, Atrial Natriuretic Factor; Sensory Receptor Cells; Serine; Threonine | 2018 |
Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism.
Topics: Adenosine Triphosphate; Allosteric Regulation; Allosteric Site; Binding Sites; Humans; Ligands; Molecular Dynamics Simulation; Phosphorylation; Protein Kinase C-alpha; Protein Kinase Inhibitors; Serine; Threonine | 2018 |
Bioformation of Volatile and Nonvolatile Metabolites by
Topics: Acetates; Alanine; Carbon; Glutamic Acid; Glycine; Isoleucine; Mannitol; Mannose; Phenylacetates; Phenylalanine; Phenylethyl Alcohol; Proline; Saccharomycopsis; Serine; Sugar Alcohols; Threonine; Time Factors | 2018 |
The effects of electrical stimulation of the peripheral vestibular system on neurochemical release in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Electric Stimulation Therapy; Electrodes; Male; Neostriatum; Parkinson Disease; Peripheral Nervous System; Rats; Rats, Wistar; Serine; Taurine; Threonine; Vestibular Nerve | 2018 |
The role of loops B and C in determining the potentiation of GABA
Topics: Allosteric Regulation; Allosteric Site; GABA Modulators; HEK293 Cells; Humans; Midazolam; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Structure, Secondary; Receptors, GABA-A; Serine; Threonine | 2018 |
AMBER and CHARMM Force Fields Inconsistently Portray the Microscopic Details of Phosphorylation.
Topics: Hydrogen Bonding; Molecular Dynamics Simulation; Phosphorylation; Protein Conformation; Serine; Threonine; Tyrosine | 2019 |
AKT phosphorylation sites of Ser473 and Thr308 regulate AKT degradation.
Topics: Binding Sites; HEK293 Cells; HeLa Cells; Humans; Mutation; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-akt; Serine; Threonine; Ubiquitin | 2019 |
The Preparation and Solution NMR Spectroscopy of Human Glycoproteins Is Accessible and Rewarding.
Topics: Acetylgalactosamine; Carbohydrate Sequence; Cell Line; Chromatography, Affinity; Gene Expression; Glycoproteins; Glycosylation; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Immunoglobulin Fc Fragments; Immunoglobulin G; Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2019 |
Kinetic and thermodynamic effects of phosphorylation on p53 binding to MDM2.
Topics: Binding Sites; Circular Dichroism; Humans; Kinetics; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Mutation; Peptide Fragments; Phosphorylation; Protein Conformation; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-mdm2; Serine; Spectrometry, Fluorescence; Thermodynamics; Threonine; Tumor Suppressor Protein p53 | 2019 |
O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
Topics: Animals; Apoptosis; Cell Line; Glucose; Humans; Immunity, Innate; Inflammation; Mice; Mice, Inbred C57BL; N-Acetylglucosaminyltransferases; Necrosis; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine | 2019 |
Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport.
Topics: Active Transport, Cell Nucleus; Cell Nucleus; Cytoplasm; Gene Expression Regulation; HEK293 Cells; Humans; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-fos; Response Elements; Serine; Threonine; Transcription Factors; Transcriptional Activation | 2019 |
Sugar Fix Keeps RIPK3 at Bay.
Topics: Humans; Inflammation; N-Acetylglucosaminyltransferases; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Sugars; Threonine | 2019 |
Mapping Post-Translational Modifications of de Novo Purine Biosynthetic Enzymes: Implications for Pathway Regulation.
Topics: Acetylation; Adenylosuccinate Lyase; Amidophosphoribosyltransferase; Amino Acid Sequence; Carbon-Nitrogen Ligases; Green Fluorescent Proteins; HEK293 Cells; Humans; Peptide Mapping; Peptides; Phosphoribosylglycinamide Formyltransferase; Phosphorylation; Protein Processing, Post-Translational; Proteomics; Proto-Oncogene Proteins c-akt; Purines; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Ubiquitination | 2019 |
Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors.
Topics: Animals; Cell Line, Tumor; Mice; Mutation; Phosphoserine; Phosphothreonine; Receptors, Granulocyte Colony-Stimulating Factor; Serine; Signal Transduction; Threonine | 2019 |
Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs.
Topics: Humans; NIMA-Related Kinases; Phosphorylation; Serine; Signal Transduction; Substrate Specificity; Threonine | 2019 |
Covalent Labeling with Diethylpyrocarbonate: Sensitive to the Residue Microenvironment, Providing Improved Analysis of Protein Higher Order Structure by Mass Spectrometry.
Topics: beta 2-Microglobulin; Diethyl Pyrocarbonate; Human Growth Hormone; Humans; Mass Spectrometry; Peptide Fragments; Protein Conformation; Serine; Threonine; Tyrosine; Ubiquitin | 2019 |
Cytotoxic activity of broussochalcone a against colon and liver cancer cells by promoting destruction complex-independent β-catenin degradation.
Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Cell Line, Tumor; Cell Survival; Chalcones; Down-Regulation; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Phosphorylation; Proteasome Endopeptidase Complex; Resorcinols; Serine; Threonine; Wnt Signaling Pathway | 2019 |
The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells.
Topics: Animals; Catalysis; Gene Knock-In Techniques; Immunity, Innate; Interleukin-1 Receptor-Associated Kinases; Macrophages; Mice; Mice, Transgenic; Multiprotein Complexes; Serine; Threonine; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2019 |
Putative Nox2 inhibitors worsen homocysteine-induced impaired acetylcholine-mediated relaxation.
Topics: Acetophenones; Acetylcholine; Animals; Aorta; Enzyme Inhibitors; Glycoproteins; Homocysteine; In Vitro Techniques; Male; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; Nitric Oxide Synthase Type III; Phosphorylation; Rabbits; Serine; Threonine; Vasodilation; Vasodilator Agents | 2019 |
Synthetic Access to 3-Substituted Pyroglutamic Acids from Tetramate Derivatives of Serine, Threonine,
Topics: Cysteine; Molecular Conformation; Pyrrolidonecarboxylic Acid; Serine; Stereoisomerism; Threonine | 2019 |
Glycine, serine and threonine metabolism confounds efficacy of complement-mediated killing.
Topics: Adenosine Triphosphate; Bacterial Outer Membrane Proteins; Chaperonins; Citric Acid Cycle; Complement Membrane Attack Complex; Complement System Proteins; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Glycine; Humans; Purines; Serine; Serum; Threonine | 2019 |
Boosting phosphorylation site prediction with sequence feature-based machine learning.
Topics: Algorithms; Animals; Binding Sites; Computational Biology; Databases, Protein; Humans; Machine Learning; Models, Molecular; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Proteins; Reproducibility of Results; Sequence Analysis, Protein; Serine; Species Specificity; Threonine; Tyrosine | 2020 |
Supplementing glycine, serine, and threonine in low protein diets for meat type chickens.
Topics: Animal Feed; Animals; Body Weight; Chickens; Diet, Protein-Restricted; Dietary Supplements; Glycine; Male; Random Allocation; Serine; Threonine | 2019 |
Proteomic Phosphosite Analysis Identified Crucial NPM-ALK-Mediated NIPA Serine and Threonine Residues.
Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cell Line; Flow Cytometry; Humans; Immunoprecipitation; Lymphoma, Large-Cell, Anaplastic; Microscopy, Fluorescence; Nuclear Proteins; Phosphoproteins; Phosphorylation; Proteomics; Serine; Signal Transduction; Threonine | 2019 |
Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation.
Topics: Cell Cycle Proteins; Fragile X Mental Retardation Protein; Humans; Nuclear Magnetic Resonance, Biomolecular; Phase Transition; Phosphorylation; Polyadenylation; Protein Biosynthesis; RNA, Messenger; Serine; Signal Transduction; Threonine; Tyrosine | 2019 |
Molecular evolution of the switch for progesterone and spironolactone from mineralocorticoid receptor agonist to antagonist.
Topics: Aldosterone; Amino Acid Substitution; Animals; Evolution, Molecular; Homeostasis; Humans; Leucine; Ligands; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Progesterone; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Receptors, Mineralocorticoid; Rodentia; Serine; Spironolactone; Structure-Activity Relationship; Threonine; Zebrafish | 2019 |
An amino-terminal threonine/serine motif is necessary for activity of the Crp/Fnr homolog, MrpC and for Myxococcus xanthus developmental robustness.
Topics: Amino Acid Sequence; Bacterial Proteins; DNA-Binding Proteins; Escherichia coli; Gene Expression Regulation, Bacterial; Myxococcus xanthus; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine; Transcription Factors; Transcription, Genetic | 2019 |
In vivo evidence for a regulatory role of phosphorylation of
Topics: Amino Acid Substitution; Arabidopsis; Arabidopsis Proteins; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Mutation; Phosphorylation; Photoperiod; Photosynthesis; Photosystem II Protein Complex; Plants, Genetically Modified; Serine; Threonine | 2019 |
Random coil chemical shifts for serine, threonine and tyrosine phosphorylation over a broad pH range.
Topics: Amino Acids; Hydrogen-Ion Concentration; Intrinsically Disordered Proteins; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Structure, Secondary; Serine; Temperature; Threonine; Tyrosine | 2019 |
Predominant cleavage of proteins N-terminal to serines and threonines using scandium(III) triflate.
Topics: Amino Acid Sequence; Chromatography, Liquid; Mesylates; Proteins; Proteolysis; Scandium; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine | 2020 |
Discovery of novel serine/threonine protein phosphatase 1 inhibitors from traditional Chinese medicine through virtual screening and biological assays.
Topics: Biological Assay; Medicine, Chinese Traditional; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Phosphatase 1; Quantitative Structure-Activity Relationship; Serine; Threonine | 2020 |
FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation.
Topics: Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Cell Proliferation; F-Box-WD Repeat-Containing Protein 7; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glycogen Synthase Kinase 3 beta; Humans; Male; Melanoma; Middle Aged; Phosphorylation; Protein Stability; Proteolysis; Serine; Signal Transduction; Skin; Skin Neoplasms; STAT2 Transcription Factor; Threonine; Tissue Array Analysis; Ubiquitination; WD40 Repeats | 2020 |
Chemical Synthesis of Native S-Palmitoylated Membrane Proteins through Removable-Backbone-Modification-Assisted Ser/Thr Ligation.
Topics: Amino Acid Sequence; Aminobutyrates; Animals; Ion Channels; Membrane Proteins; Muscle Proteins; Palmitates; Peptides; Proteolipids; Rabbits; Serine; Solid-Phase Synthesis Techniques; Solubility; Threonine | 2020 |
Use of Serine/Threonine Ligation for the Total Chemical Synthesis of HMGA1a Protein with Site-Specific Lysine Acetylations.
Topics: Acetylation; Amino Acid Sequence; Chemistry Techniques, Synthetic; HMGA1a Protein; Lysine; Peptide Fragments; Protein Processing, Post-Translational; Serine; Threonine | 2019 |
Gigaxonin glycosylation regulates intermediate filament turnover and may impact giant axonal neuropathy etiology or treatment
Topics: Acetylglucosamine; Antigens, Neoplasm; Binding Sites; Cell Line; Cytoskeletal Proteins; Epigenesis, Genetic; Genetic Therapy; Giant Axonal Neuropathy; Glycosylation; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Intercellular Signaling Peptides and Proteins; Intermediate Filament Proteins; Models, Biological; Nutritional Status; Proteasome Endopeptidase Complex; Protein Binding; Proteostasis; Serine; Threonine; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2020 |
Thr420 and Ser454 of ZmCCaMK play a crucial role in brassinosteroid-induced antioxidant defense in maize.
Topics: Adaptation, Physiological; Antioxidants; Brassinosteroids; Calcium-Calmodulin-Dependent Protein Kinases; Droughts; Mutant Proteins; Nicotiana; Phosphorylation; Plant Proteins; Plants, Genetically Modified; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine; Zea mays | 2020 |
Feature of Heart Rate Variability and Metabolic Mechanism in Female College Students with Depression.
Topics: Adolescent; Autonomic Nervous System; Depression; Fatigue; Female; Glycine; Heart Rate; Humans; Metabolomics; Monitoring, Physiologic; Pyrimidines; Serine; Steroids; Stress, Physiological; Students; Threonine; Tyrosine; Ubiquinone; Urine; Young Adult | 2020 |
Phosphorylation Modulates the Coregulatory Protein Exchange of the Nuclear Receptor Pregnane X Receptor.
Topics: Animals; Cell Line, Tumor; Cells, Cultured; Hepatocytes; Humans; Mice; Phosphorylation; Pregnane X Receptor; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Serine; Threonine | 2020 |
PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72.
Topics: HEK293 Cells; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mitochondria; Parkinsonian Disorders; Phosphorylation; Protein Kinases; rab GTP-Binding Proteins; Serine; Threonine | 2020 |
Melanopsin Carboxy-terminus phosphorylation plasticity and bulk negative charge, not strict site specificity, achieves phototransduction deactivation.
Topics: beta-Arrestin 1; HEK293 Cells; Humans; Light Signal Transduction; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Binding; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Rod Opsins; Serine; Threonine | 2020 |
Structural basis for ion selectivity in TMEM175 K
Topics: HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Models, Molecular; Potassium; Potassium Channels; Protein Conformation; Serine; Threonine | 2020 |
Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3' processing and transcription termination that functions via its effects on CTD phosphatase Ssu72.
Topics: Cell Cycle Proteins; Cleavage And Polyadenylation Specificity Factor; Gene Deletion; Gene Expression Regulation, Fungal; NIMA-Interacting Peptidylprolyl Isomerase; Nuclear Proteins; Peptidylprolyl Isomerase; Phosphates; Phosphoprotein Phosphatases; Phosphorylation; Protein Domains; Pyrophosphatases; Regulon; RNA 3' End Processing; RNA Polymerase II; RNA-Seq; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Serine; Threonine; Transcription Termination, Genetic | 2020 |
Ser and Thr acceptor preferences of the GalNAc-Ts vary among isoenzymes to modulate mucin-type O-glycosylation.
Topics: Glycosylation; Humans; Isoenzymes; Mucins; N-Acetylgalactosaminyltransferases; Polypeptide N-acetylgalactosaminyltransferase; Serine; Threonine | 2020 |
Protein Phosphorylation in Serine Residues Correlates with Progression from Precancerous Lesions to Cervical Cancer in Mexican Patients.
Topics: Adult; Cervix Uteri; Clusterin; Disease Progression; Female; Heat-Shock Proteins; Humans; Keratin-19; Keratin-8; Mexico; Middle Aged; Molecular Chaperones; Papillomavirus Infections; Phosphorylation; Precancerous Conditions; Proteomics; Serine; Squamous Intraepithelial Lesions of the Cervix; Threonine; Uterine Cervical Neoplasms; Young Adult | 2020 |
The effect of reduced dietary glycine and serine and supplemental threonine on growth performance, protein deposition in carcass and viscera, and skin collagen abundance of nursery pigs fed low crude protein diets.
Topics: Animal Feed; Animals; Body Composition; Collagen; Diet; Diet, Protein-Restricted; Dietary Proteins; Dietary Supplements; Glycine; Male; Serine; Skin; Skin Physiological Phenomena; Swine; Threonine; Viscera; Weight Gain | 2020 |
Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in Mice.
Topics: Animals; Caloric Restriction; Fatty Acids, Unsaturated; Female; Glucose; Glucose Tolerance Test; Glycine; Longevity; Male; Metabolomics; Mice; Mice, Inbred C57BL; Serine; Threonine | 2020 |
Phosphorylation status of BolA affects its role in transcription and biofilm development.
Topics: Amino Acid Sequence; Binding Sites; Biofilms; Blotting, Western; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Mass Spectrometry; Mutation; Phosphorylation; Protein Domains; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Threonine; Transcription Factors | 2021 |
Recognition of physiological phosphorylation sites by p21-activated kinase 4.
Topics: beta Catenin; Catalytic Domain; Crystallography, X-Ray; Humans; Lim Kinases; Mutation; p21-Activated Kinases; Peptide Fragments; Phosphorylation; Serine; Threonine | 2020 |
Molecular Basis for Ser/Thr Specificity in PKA Signaling.
Topics: Humans; Protein Kinases; Serine; Signal Transduction; Threonine | 2020 |
Resistance to serine in Bacillus subtilis: identification of the serine transporter YbeC and of a metabolic network that links serine and threonine metabolism.
Topics: Amino Acid Transport Systems; Bacillus subtilis; Bacterial Proteins; Drug Resistance, Bacterial; Escherichia coli; Metabolic Networks and Pathways; Mutation; Serine; Threonine | 2020 |
Topics: Carcinoma, Squamous Cell; Cytochrome P-450 Enzyme System; Drug Design; Head and Neck Neoplasms; Humans; Molecular Docking Simulation; Monoamine Oxidase; Mouth Neoplasms; Proto-Oncogene Proteins c-akt; Serine; Squamous Cell Carcinoma of Head and Neck; Threonine | 2021 |
Generation of a serine/threonine-protein kinase LATS1 gene-edited iPSC MUSIi012-A-3.
Topics: Animals; Gene Editing; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine; Transcription Factors | 2020 |
Improved GROMOS 54A7 Charge Sets for Phosphorylated Tyr, Ser, and Thr to Deal with pH-Dependent Binding Phenomena.
Topics: Binding Sites; Hydrogen-Ion Concentration; Molecular Dynamics Simulation; Phosphorylation; Serine; Threonine; Tyrosine | 2020 |
Novel serine/threonine-O-glycosylation with N-acetylneuraminic acid and 3-deoxy-D-manno-octulosonic acid by bacterial flagellin glycosyltransferases.
Topics: Flagellin; Glycosylation; Glycosyltransferases; N-Acetylneuraminic Acid; Serine; Sugar Acids; Threonine | 2021 |
Intracellular Ser/Thr/Tyr phosphoproteome of the oral commensal Streptococcus gordonii DL1.
Topics: Bacterial Proteins; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Humans; Mouth; Phosphoproteins; Phosphorylation; Serine; Streptococcus gordonii; Tandem Mass Spectrometry; Threonine; Tyrosine | 2020 |
DeepPPSite: A deep learning-based model for analysis and prediction of phosphorylation sites using efficient sequence information.
Topics: Amino Acid Sequence; Animals; Computational Biology; Databases, Protein; Deep Learning; Models, Statistical; Phosphorylation; Protein Processing, Post-Translational; ROC Curve; Sequence Analysis, Protein; Serine; Threonine; Tyrosine | 2021 |
Spectral quality overrides software score-A brief tutorial on the analysis of peptide fragmentation data for mass spectrometry laymen.
Topics: Artifacts; Data Accuracy; Mass Spectrometry; Metabolomics; Peptide Fragments; Phosphorylation; Proteomics; Serine; Software; Threonine | 2021 |
The O-GlcNAc transferase OGT is a conserved and essential regulator of the cellular and organismal response to hypertonic stress.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Gene Expression Regulation, Enzymologic; Humans; N-Acetylglucosaminyltransferases; Osmotic Pressure; Protein Domains; Protein Processing, Post-Translational; Serine; Threonine | 2020 |
Evaluation of glycation reaction of ovalbumin with dextran: Glycation sites identification by capillary liquid chromatography coupled with tandem mass spectrometry.
Topics: Chromatography, Liquid; Dextrans; Glycation End Products, Advanced; Glycosylation; Hydrophobic and Hydrophilic Interactions; Microwaves; Ovalbumin; Serine; Tandem Mass Spectrometry; Threonine | 2021 |
Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation.
Topics: Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; Protein Binding; Protein Conformation; Protein Domains; Protein Phosphatase 1; Serine; Threonine | 2021 |
β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes.
Topics: Adipocytes, Brown; Animals; Cyclic AMP-Dependent Protein Kinases; Energy Metabolism; Enzyme Activation; Gene Expression Regulation; HEK293 Cells; Humans; Male; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Phosphorylation; Receptors, Adrenergic, beta; Serine; Threonine | 2020 |
O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation.
Topics: Acetylglucosamine; Breast Neoplasms; Female; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Protein Processing, Post-Translational; Proteolysis; Serine; Signal Transduction; Smad4 Protein; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Ubiquitin | 2020 |
Water-Soluble α-Amino Acid Complexes of Molybdenum as Potential Antidotes for Cyanide Poisoning: Synthesis and Catalytic Studies of Threonine, Methionine, Serine, and Leucine Complexes.
Topics: A549 Cells; Amino Acids; Antidotes; Cell Survival; Cyanides; Humans; Inhibitory Concentration 50; Leucine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methionine; Models, Molecular; Molecular Structure; Molybdenum; Serine; Solubility; Spectrophotometry, Infrared; Thiocyanates; Threonine; Water | 2020 |
mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1.
Topics: Amino Acid Motifs; Autoantigens; HEK293 Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Naphthyridines; Phosphorylation; Protein Binding; Protein Biosynthesis; Ribonucleoproteins; Serine; Sirolimus; SS-B Antigen; Threonine; Tyrosine | 2021 |
Impact of immune checkpoint gene CD155 Ala67Thr and CD226 Gly307Ser polymorphisms on small cell lung cancer clinical outcome.
Topics: Aged; Alanine; Amino Acid Substitution; Antigens, Differentiation, T-Lymphocyte; Carcinoma, Small Cell; Female; Glycine; Humans; Lung Neoplasms; Male; Polymorphism, Genetic; Receptors, Virus; Serine; Threonine; Treatment Outcome | 2021 |
Protein kinase G phosphorylates the Alzheimer's disease-associated tau protein at distinct Ser/Thr sites.
Topics: Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Aggregates; Rats, Sprague-Dawley; Serine; tau Proteins; Threonine | 2021 |
DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells.
Topics: Caveolin 1; Cell Line, Tumor; Cell Proliferation; Cholesterol; Gene Knockout Techniques; Glycogen Synthase Kinase 3 beta; Humans; Membrane Microdomains; Nerve Tissue Proteins; Oxidoreductases Acting on CH-CH Group Donors; Phosphorylation; Protein Phosphatase 2; Serine; Signal Transduction; tau Proteins; Threonine | 2021 |
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry.
Topics: Amino Acid Motifs; Animals; Aurora Kinase A; Cell Cycle Proteins; Cell Line, Tumor; Cyclin A2; Cyclin-Dependent Kinase 2; Enzyme Activation; Female; Humans; Mitosis; Oocytes; Phosphorylation; Polo-Like Kinase 1; Proline; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Serine; Threonine; Xenopus laevis | 2021 |
Analgesic Activity of Jin Ling Zi Powder and Its Single Herbs: A Serum Metabonomics Study.
Topics: Analgesics; Animals; Aspirin; Biomarkers; Body Weight; Drugs, Chinese Herbal; Glycine; Glyoxylates; Inositol Phosphates; Isoleucine; Leucine; Metabolomics; Mice; Powders; RNA, Transfer; Serine; Threonine; Valine | 2022 |
Open stomata 1 exhibits dual serine/threonine and tyrosine kinase activity in regulating abscisic acid signaling.
Topics: Abscisic Acid; Arabidopsis Proteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Serine; Threonine | 2021 |
Glycogen synthase kinase-3 beta (GSK3β)-mediated phosphorylation of ETS1 promotes progression of ovarian carcinoma.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Movement; Disease Progression; Female; Glycogen Synthase Kinase 3 beta; Humans; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Models, Biological; Mutation; Neoplasm Staging; Ovarian Neoplasms; Phosphorylation; Protein Binding; Protein Stability; Proto-Oncogene Protein c-ets-1; Serine; Substrate Specificity; Threonine | 2021 |
A deep learning based approach for prediction of Chlamydomonas reinhardtii phosphorylation sites.
Topics: Chlamydomonas reinhardtii; Chromatography, Liquid; Deep Learning; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Proteome; Serine; Tandem Mass Spectrometry; Threonine | 2021 |
Root angle in maize influences nitrogen capture and is regulated by calcineurin B-like protein (CBL)-interacting serine/threonine-protein kinase 15 (ZmCIPK15).
Topics: Calcineurin; Genome-Wide Association Study; Nitrogen; Plant Roots; Protein Kinases; Serine; Threonine; Water; Zea mays | 2022 |
Composition of Amino Acids in Foodstuffs for Humans and Animals.
Topics: Amino Acids; Animals; Humans; Isoleucine; Leucine; Methionine; Serine; Swine; Threonine; Tyrosine | 2021 |
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1).
Topics: Apoptosis; Humans; Imidazoles; Indoles; NAD; NAD(P)H Dehydrogenase (Quinone); Quinones; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Threonine | 2021 |
Formation of catanionic vesicles by threonine-derived surfactants and gemini surfactants based on conventional or serine-derived headgroups: designing versatile and cytocompatible nanocarriers.
Topics: Micelles; Serine; Surface-Active Agents; Threonine | 2021 |
Influence of Stereochemistry on the Monolayer Characteristics of
Topics: Serine; Thermodynamics; Threonine; Water; X-Ray Diffraction | 2021 |
Transcriptome profiling reveals sex-specific gene expressions in pupal and adult stages of the mosquito Culex pipiens.
Topics: Animals; Culex; Culicidae; Female; Gene Expression; Gene Expression Profiling; Male; Mosquito Vectors; Protein Kinases; Pupa; Serine; Threonine | 2022 |
Serine/threonine ligation-assisted chemical synthesis of HMGA1a protein with site-specific post-translational modifications.
Topics: HMGA1a Protein; Phosphorylation; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Solid-Phase Synthesis Techniques; Threonine | 2021 |
Investigation of sequon engineering for improved O-glycosylation by the human polypeptide N-acetylgalactosaminyl transferase T2 isozyme and two orthologues.
Topics: Amino Acid Sequence; Catalytic Domain; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Escherichia coli; Glycosylation; Human Growth Hormone; Humans; Interferon alpha-2; Isoenzymes; Kinetics; Mucins; N-Acetylgalactosaminyltransferases; Polypeptide N-acetylgalactosaminyltransferase; Polysaccharides; Protein Engineering; Recombinant Proteins; Sequence Alignment; Serine; Synthetic Biology; Threonine | 2021 |
Design and Development of a Chemical Probe for Pseudokinase Ca
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Drug Design; Humans; Molecular Probes; Protein Kinase Inhibitors; Serine; Structure-Activity Relationship; Substrate Specificity; Threonine | 2021 |
Extensive regulation of enzyme activity by phosphorylation in Escherichia coli.
Topics: Binding Sites; Enzymes; Escherichia coli; Escherichia coli Proteins; Mass Spectrometry; Metabolomics; Mutation; Phosphorylation; Protein Processing, Post-Translational; Proteome; Proteomics; Serine; Threonine; Tyrosine | 2021 |
Serine/Threonine-Protein Kinase 3 Facilitates Myocardial Repair After Cardiac Injury Possibly Through the Glycogen Synthase Kinase-3β/β-Catenin Pathway.
Topics: Animals; Apoptosis; beta Catenin; Glycogen Synthase Kinase 3 beta; Mice; Myocardial Infarction; Myocytes, Cardiac; Protein Serine-Threonine Kinases; Reperfusion Injury; Serine; Threonine | 2021 |
Bioinformatic Analysis of Lytic Polysaccharide Monooxygenases Reveals the Pan-Families Occurrence of Intrinsically Disordered C-Terminal Extensions.
Topics: Amino Acid Sequence; Binding Sites; Buffers; Computational Biology; Fungi; Gene Expression Regulation, Fungal; Intrinsically Disordered Proteins; Mixed Function Oxygenases; Polysaccharides; Serine; Threonine; Viruses | 2021 |
Discerning Tyrosine Phosphorylation from Multiple Phosphorylations Using a Nanofluidic Logic Platform.
Topics: Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Serine; Threonine; Tyrosine | 2021 |
Integrated computational approach for
Topics: Humans; Ligands; Molecular Docking Simulation; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyridines; Pyrimidines; Serine; Threonine | 2022 |
Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker.
Topics: A549 Cells; Amino Acid Sequence; Binding Sites; Cell Line, Tumor; Crystallography, X-Ray; Gene Expression; HEK293 Cells; Humans; Models, Molecular; Molecular Mimicry; PC-3 Cells; Phosphorylation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Receptor, EphA2; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Static Electricity; Sterile Alpha Motif; Substrate Specificity; Threonine | 2021 |
Relationship between indirect genetic effects for growth, environmental enrichment, coping style and sex with the serum metabolome profile of pigs.
Topics: Adaptation, Psychological; Animals; Female; Glycine; Housing, Animal; Magnetic Resonance Spectroscopy; Male; Metabolomics; Orchiectomy; Selective Breeding; Serine; Swine; Threonine | 2021 |
TTF-1: A Well-Favored Addition to the Immunohistochemistry Armamentarium as a Diagnostic Marker of SEGA.
Topics: Astrocytoma; Brain Neoplasms; Child; Ependymoma; Glioblastoma; Humans; Immunohistochemistry; Neurocytoma; Proto-Oncogene Proteins c-akt; Serine; Threonine; Thyroid Nuclear Factor 1; Tuberous Sclerosis | 2022 |
SGIP1 modulates kinetics and interactions of the cannabinoid receptor 1 and G protein-coupled receptor kinase 3 signalosome.
Topics: Carrier Proteins; GTP-Binding Proteins; Kinetics; Phosphorylation; Receptors, Cannabinoid; Serine; Threonine | 2022 |
Proline-serine-threonine-repeat region of MDC1 mediates Chk1 phosphorylation and the DNA double-strand break repair.
Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Checkpoint Kinase 1; DNA Breaks, Double-Stranded; Humans; Phosphorylation; Proline; Serine; Threonine; Transfection | 2022 |
Clostridioides difficile Phosphoproteomics Shows an Expansion of Phosphorylated Proteins in Stationary Growth Phase.
Topics: Clostridioides; Clostridioides difficile; Serine; Threonine; Tyrosine | 2022 |
Metabolomics and microbiomes for discovering biomarkers of antituberculosis drugs-induced hepatotoxicity.
Topics: Adult; Antitubercular Agents; Biomarkers; Chemical and Drug Induced Liver Injury; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Male; Metabolomics; Microbiota; Middle Aged; RNA, Ribosomal, 16S; Serine; Threonine | 2022 |
Plasma Metabolomic Changes in Children with Cerebral Palsy Exposed to Botulinum Neurotoxin.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Child; Cysteine; Glycine; Humans; Injections, Intramuscular; Methionine; Muscle Spasticity; Neuromuscular Agents; Serine; Threonine; Treatment Outcome | 2022 |
AKT serine/threonine kinase 2-mediated phosphorylation of fascin threonine 403 regulates esophageal cancer progression.
Topics: Actins; Carrier Proteins; Cell Line, Tumor; Esophageal Neoplasms; Humans; Microfilament Proteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2022 |
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge.
Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine | 2022 |
Global profiling of phosphorylation-dependent changes in cysteine reactivity.
Topics: Cysteine; Humans; Phosphorylation; Protein Processing, Post-Translational; Proteome; Proteomics; Serine; Threonine | 2022 |
Hepatic kinome atlas: An in-depth identification of kinase pathways in liver fibrosis of humans and rodents.
Topics: Animals; Collagen; Discoidin Domain Receptors; Fibrosis; Humans; Liver; Liver Cirrhosis; Liver Diseases; Mice; Protein Kinases; Receptor, Insulin; Rodentia; Serine; Threonine | 2022 |
Specificity and Reactivity of
Topics: Bacterial Proteins; Mycobacterium tuberculosis; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2022 |
Proteomic analysis reveals the heterogeneity of metabolic reprogramming in lacrimal gland tumors.
Topics: Chromatography, Liquid; Eye Neoplasms; Glycine; Humans; Lacrimal Apparatus; Lacrimal Apparatus Diseases; Proteomics; Serine; Tandem Mass Spectrometry; Threonine | 2022 |
Cerebrospinal fluid amino acids glycine, serine, and threonine in nonketotic hyperglycinemia.
Topics: Amino Acids; Cross-Sectional Studies; Glycine; Humans; Hyperglycinemia, Nonketotic; Infant, Newborn; Serine; Threonine | 2022 |
Metabolomics study of the effect of Danggui Buxue Tang on rats with chronic fatigue syndrome.
Topics: Angelica sinensis; Animals; Drugs, Chinese Herbal; Fatigue Syndrome, Chronic; Glycine; Metabolomics; Rats; Serine; Threonine; Tyrosine | 2022 |
T-cell Dysfunction upon Expression of MYC with Altered Phosphorylation at Threonine 58 and Serine 62.
Topics: Animals; Carcinogenesis; Lymphoma, T-Cell; Mice; Phosphorylation; Proto-Oncogene Proteins c-myc; Serine; T-Lymphocytes; Threonine; Transcription Factors | 2022 |
Inhibition of p38 MAPK decreases hyperglycemia-induced nephrin endocytosis and attenuates albuminuria.
Topics: Albuminuria; Endocytosis; Humans; Hyperglycemia; Membrane Proteins; p38 Mitogen-Activated Protein Kinases; Podocytes; Protein Kinase C-alpha; Serine; Threonine | 2022 |
A pancancer analysis of the carcinogenic role of receptor-interacting serine/threonine protein kinase-2 (RIPK2) in human tumours.
Topics: Carcinogenesis; Carcinogens; Humans; Neoplasms; NF-kappa B; Receptor-Interacting Protein Serine-Threonine Kinase 2; Serine; Threonine | 2022 |
High Receptor-interacting Serine/Threonine-protein Kinase 3 (RIP3) Expression Serves as an Independent Poor Prognostic Factor for Triple-negative Breast Carcinoma.
Topics: Breast; Humans; Prognosis; Serine; Threonine; Triple Negative Breast Neoplasms | 2022 |
GC-MS based metabolite fingerprinting of serous ovarian carcinoma and benign ovarian tumor.
Topics: Benzoic Acid; Biomarkers; Creatinine; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Glycine; Humans; Metabolomics; Ovarian Neoplasms; Pyrrolidonecarboxylic Acid; RNA, Transfer; Serine; Threonine | 2022 |
Development of an off-line heart cutting two-dimensional HPLC system for enantioselective analysis of serine, threonine and allo-threonine in human physiological fluids.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Humans; Serine; Stereoisomerism; Threonine | 2022 |
Unraveling Pathways of Health and Lifespan with Integrated Multiomics Approaches.
Topics: Animals; Diet; Longevity; Metabolomics; Mice; Serine; Threonine | 2022 |
Phosphorylation of serine residues S252, S268/S269, and S879 in p120 catenin activates migration of presomitic mesoderm in gastrulating zebrafish embryos.
Topics: Animals; Cadherins; Catenins; Glutamic Acid; Mesoderm; Mice; Phosphorylation; Serine; Threonine; Zebrafish | 2022 |
Discovery of Potent and Selective Receptor-Interacting Serine/Threonine Protein Kinase 2 (RIPK2) Inhibitors for the Treatment of Inflammatory Bowel Diseases (IBDs).
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Humans; Inflammatory Bowel Diseases; Protein Kinase Inhibitors; Receptor-Interacting Protein Serine-Threonine Kinase 2; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Threonine | 2022 |
A RAC-alpha serine/threonine-protein kinase (CgAKT1) involved in the synthesis of CgIFNLP in oyster Crassostrea gigas.
Topics: Animals; Crassostrea; Fluoresceins; Gene Expression Regulation; HEK293 Cells; Hemocytes; Humans; Immunity, Innate; Interferons; Poly I-C; Proto-Oncogene Proteins c-akt; RNA, Messenger; Serine; Sulfonic Acids; Threonine | 2022 |
SET improved oocyte maturation by serine/threonine protein phosphatase 2A and inhibited oocyte apoptosis in mouse oocytes.
Topics: Animals; Apoptosis; Female; Humans; Mice; Mice, Inbred ICR; Oocytes; Polycystic Ovary Syndrome; Protein Phosphatase 2; RNA, Small Interfering; Serine; Threonine | 2022 |
Role of serine/threonine protein kinase STN7 in the formation of two distinct photosystem I supercomplexes in Physcomitrium patens.
Topics: Arabidopsis; Arabidopsis Proteins; Bryopsida; Light; Light-Harvesting Protein Complexes; Phosphorylation; Photosystem I Protein Complex; Photosystem II Protein Complex; Protein Serine-Threonine Kinases; Serine; Threonine | 2022 |
Serine/Threonine Ligation and Cysteine/Penicillamine Ligation.
Topics: Cysteine; Esters; Penicillamine; Peptides; Serine; Threonine | 2022 |
PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma.
Topics: Carcinoma, Hepatocellular; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Liver Neoplasms; Macrophages; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Serine; Threonine; Tumor Microenvironment | 2022 |
Blunted Amphetamine-induced Reinforcing Behaviors and Transporter Downregulation in Knock-in Mice Carrying Alanine Mutations at Threonine-258 and Serine-259 of Norepinephrine Transporter.
Topics: Alanine; Amphetamine; Animals; Down-Regulation; Male; Membrane Transport Proteins; Mice; Mutation; Norepinephrine Plasma Membrane Transport Proteins; Serine; Threonine | 2022 |
Role of the gut-microbiota-metabolite axis in the rotenone model of early-stage Parkinson's Disease.
Topics: Alanine; Animals; Asparagine; Gastrointestinal Microbiome; Glutamine; Hydroxyproline; Methionine; Mice; Parkinson Disease; Rotenone; Serine; Threonine | 2022 |
PrrA modulates Mycobacterium tuberculosis response to multiple environmental cues and is critically regulated by serine/threonine protein kinases.
Topics: Bacterial Proteins; Cues; Gene Expression Regulation, Bacterial; Humans; Hypoxia; Mycobacterium tuberculosis; Protein Serine-Threonine Kinases; Serine; Threonine; Transcription Factors | 2022 |
Role of serine/threonine protein phosphatase PrpN in the life cycle of Bacillus anthracis.
Topics: Animals; Bacillus anthracis; Bacterial Proteins; Life Cycle Stages; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine | 2022 |
Treatment with FRAX486 rescues neurobehavioral and metabolic alterations in a female mouse model of CDKL5 deficiency disorder.
Topics: Animals; Disease Models, Animal; Disks Large Homolog 4 Protein; Epileptic Syndromes; Female; Glucose; Male; Mice; Mice, Knockout; p21-Activated Kinases; Protein Serine-Threonine Kinases; Pyridones; Pyrimidines; Serine; Spasms, Infantile; Threonine | 2022 |
Multiple Viral Protein Genome-Linked Proteins Compensate for Viral Translation in a Positive-Sense Single-Stranded RNA Virus Infection.
Topics: 5' Untranslated Regions; Animals; Cell Line; Dicistroviridae; Drosophila; Genome, Viral; Internal Ribosome Entry Sites; Mutation; Protein Biosynthesis; RNA Virus Infections; RNA, Viral; Serine; Threonine; Viral Load; Viral Proteins | 2022 |
Stabilization of the c-Myc Protein via the Modulation of Threonine 58 and Serine 62 Phosphorylation by the Disulfiram/Copper Complex in Oral Cancer Cells.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Copper; Disulfiram; Humans; Mouth Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-myc; Reactive Oxygen Species; Serine; Threonine | 2022 |
Targeting non-alcoholic fatty liver disease: Design, X-ray co-crystal structure and synthesis of 'first-in-kind' inhibitors of serine/threonine kinase25.
Topics: Humans; Intracellular Signaling Peptides and Proteins; Molecular Docking Simulation; Non-alcoholic Fatty Liver Disease; Oxazines; Protein Serine-Threonine Kinases; Serine; Threonine; X-Rays | 2022 |
Pregnane X receptor promotes liver enlargement in mice through the spatial induction of hepatocyte hypertrophy and proliferation.
Topics: Animals; Anions; ATP Binding Cassette Transporter, Subfamily B; Cell Proliferation; Cyclin B1; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Digitonin; Hepatocytes; Hepatomegaly; Hypertrophy; Liver; Mice; Mice, Inbred C57BL; NIMA-Related Kinases; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Retinoblastoma-Like Protein p130; Serine; Threonine; Triglycerides | 2022 |
A new perspective on endocrine disrupting effects of triphenyltin on marine medaka: From brain transcriptome, gut content metabolome and behavior.
Topics: Animals; Brain; Glycine; Humans; Metabolome; Organotin Compounds; Oryzias; PPAR gamma; Serine; Threonine; Transcriptome; Water Pollutants, Chemical | 2022 |
Yogurt Benefits Bone Mineralization in Ovariectomized Rats with Concomitant Modulation of the Gut Microbiome.
Topics: Animals; Calcification, Physiologic; Calcium; Calcium Carbonate; Calcium, Dietary; Fatty Acids, Volatile; Female; Gastrointestinal Microbiome; Glycine; Inulin; Rats; Serine; Threonine; Yogurt | 2022 |
[Effect and mechanism of Dahuang Zhechong Pills against testicular aging in rats by inhibiting necroptosis signaling pathway].
Topics: Aging; Animals; Drugs, Chinese Herbal; Male; Necroptosis; Protein Kinases; Rats; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Signal Transduction; Testis; Threonine | 2022 |
The amino acid profile of Camelina sativa seeds correlates with the strongest immune response in dairy ewes.
Topics: Amino Acids; Animal Feed; Animals; Brassicaceae; Diet; Fatty Acids; Fatty Acids, Unsaturated; Female; Immunity, Innate; Interferon Regulatory Factors; Interferon-beta; Interleukin-10; Interleukin-1beta; Interleukin-8; Lysine; Mitogen-Activated Protein Kinases; Seeds; Serine; Sheep; Threonine; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins; Tyrosine | 2022 |
In Silico Positional Analogue Scanning with Amber GPU-TI.
Topics: Amber; Cyclin-Dependent Kinase 8; Halogens; Histone Acetyltransferases; Humans; Lysine; Nitrogen; Orexin Receptors; Orexins; Phosphoric Diester Hydrolases; PPAR gamma; Proto-Oncogene Proteins c-akt; Serine; Tankyrases; Threonine | 2022 |
Network pharmacology combined with metabolomics reveals the mechanism of Fuzi decoction against chronic heart failure in rats.
Topics: Animals; beta-Alanine; Chronic Disease; Coenzyme A; Diterpenes; Drugs, Chinese Herbal; Glycine; Glyoxylates; Heart Failure; Lactates; Metabolomics; Network Pharmacology; Pyruvates; Rats; RNA, Transfer; Serine; Threonine | 2022 |
The Detoxification Enzymatic Responses of Plutella xylostella (Lepidoptera: Plutellidae) to Cantharidin.
Topics: Animals; Cantharidin; Carboxylic Ester Hydrolases; Cytochrome P-450 Enzyme System; Glutathione; Insecticides; Larva; Lepidoptera; Moths; Phosphoric Monoester Hydrolases; Serine; Threonine; Transferases | 2022 |
The combination of microbiome and metabolome to analyze the cross-cooperation mechanism of
Topics: Alanine; Animals; Echinacea; Fatty Acids, Volatile; Gastrointestinal Microbiome; Glycine; Glycosphingolipids; Humans; Leucine; Metabolome; Mice; Microbiota; Ornithine; Phenylalanine; Polysaccharides; Porphyrins; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
GpsB Promotes PASTA Kinase Signaling and Cephalosporin Resistance in
Topics: Anti-Bacterial Agents; Cephalosporin Resistance; Cephalosporins; Enterococcus faecalis; Phosphotransferases; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine | 2022 |
O-GlcNAc transferase is important for homology-directed repair.
Topics: Acetylglucosamine; Chromosome Breakage; DNA; Humans; N-Acetylglucosaminyltransferases; Serine; Threonine | 2022 |
Recent strains of influenza D virus create a new genetic cluster for European strains.
Topics: Alanine; Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Cattle Diseases; Glycine; Nucleotides; Orthomyxoviridae; Orthomyxoviridae Infections; Phylogeny; Proline; Serine; Thogotovirus; Threonine; Valine | 2022 |
Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.
Topics: CD28 Antigens; Insulin; Insulin Receptor Substrate Proteins; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Threonine | 2022 |
Gene signature and connectivity mapping to assist with drug prediction for pancreatic ductal adenocarcinoma.
Topics: Aurora Kinase A; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Computational Biology; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genome-Wide Association Study; Humans; Lapatinib; Pancreatic Neoplasms; Prospective Studies; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); RNA; Roscovitine; Serine; Threonine; Trypsin | 2022 |
[Bioinformatics analysis of differentially expressed genes associated with chronic schistosomiasis japonica-induced hepatic fibrosis].
Topics: Adenosine Monophosphate; Calcium; Coenzyme A; Computational Biology; Fatty Acids; Humans; Liver Cirrhosis; Mitogen-Activated Protein Kinases; Oxidoreductases; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Proto-Oncogene Proteins c-akt; Schistosomiasis japonica; Serine; Somatomedins; Sulfur Compounds; Threonine | 2022 |
Transcriptomic and proteomic analysis of Staphylococcus aureus response to cuminaldehyde stress.
Topics: Adenosine Triphosphate; Amino Acids, Branched-Chain; Animals; Anti-Bacterial Agents; Bacterial Proteins; Benzaldehydes; Betaine; Cattle; Cymenes; Cysteine; DNA, Single-Stranded; Fatty Acids; Gene Expression Regulation, Bacterial; Glycine; Iron; Methionine; Peptidoglycan; Proteomics; Serine; Staphylococcal Infections; Staphylococcus aureus; Threonine; Transcriptome | 2022 |
The cell cortex-localized protein CHDP-1 is required for dendritic development and transport in C. elegans neurons.
Topics: Actins; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dendrites; Protein Serine-Threonine Kinases; Sensory Receptor Cells; Serine; Threonine | 2022 |
Characterization of a new Bacillus velezensis as a powerful biocontrol agent against tomato gray mold.
Topics: Agar; Antifungal Agents; Antioxidants; Bacillus; Catalase; Cellulose; Complex Mixtures; Glucose; Glycine; Peptide Hydrolases; Phosphoric Monoester Hydrolases; Plant Diseases; Salicylic Acid; Serine; Siderophores; Solanum lycopersicum; Sulfur; Superoxide Dismutase; Threonine | 2022 |
Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.
Topics: Angiogenesis Inhibitors; Humans; Isoenzymes; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Serine; Tamoxifen; Threonine | 2022 |
Functional Divergence in a Multi-gene Family Is a Key Evolutionary Innovation for Anaerobic Growth in Saccharomyces cerevisiae.
Topics: Anaerobiosis; Carrier Proteins; Evolution, Molecular; Gene Duplication; Glycoproteins; Phylogeny; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine | 2022 |
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors.
Topics: Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinase Inhibitor Proteins; Ligands; Machine Learning; Molecular Docking Simulation; Proline; Reproducibility of Results; Serine; Threonine | 2022 |
Targeted Bottom-Up Mass Spectrometry Approach for the Relative Quantification of Post-Translational Modification of Bovine κ-Casein during Milk Fermentation.
Topics: Allergens; Amino Acids; Caseins; Fermentation; Mass Spectrometry; Micelles; Milk Proteins; Protein Processing, Post-Translational; Reproducibility of Results; Serine; Threonine | 2022 |
NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovirus B, Human; Glutamic Acid; Glutamine; Glycine; Mice; Mice, Inbred BALB C; Myocarditis; Niacin; Niacinamide; Serine; Taurine; Threonine | 2022 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
DSTYK inhibition increases the sensitivity of lung cancer cells to T cell-mediated cytotoxicity.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; T-Lymphocytes; Threonine; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Tyrosine | 2022 |
A functional interaction between liprin-α1 and B56γ regulatory subunit of protein phosphatase 2A supports tumor cell motility.
Topics: Breast Neoplasms; Cell Movement; Female; Holoenzymes; Humans; Protein Phosphatase 2; Serine; Threonine | 2022 |
Targeting aurora kinase a (AURKA) in cancer: molecular docking and dynamic simulations of potential AURKA inhibitors.
Topics: Animals; Aurora Kinase A; Cell Line, Tumor; Humans; Mammals; Molecular Docking Simulation; Neoplasms; Piperazines; Serine; Thiazoles; Threonine | 2022 |
Differential expression patterns of genes associated with metabolisms, muscle growth and repair in Pectoralis major muscles of fast- and medium-growing chickens.
Topics: AMP-Activated Protein Kinases; Animals; Chickens; Matrix Metalloproteinase 14; Muscular Diseases; Pectoralis Muscles; Poultry Diseases; Serine; Threonine | 2022 |
Exploring AI-2-mediated interspecies communications within rumen microbial communities.
Topics: Animals; Bacteria; Bacterial Proteins; Histidine; Homoserine; Lactones; Methyl-Accepting Chemotaxis Proteins; Microbiota; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Rumen; Serine; Threonine | 2022 |
Inhibition of 26S proteasome enhances AKAP3-mediated cAMP-PKA signaling during boar sperm capacitation.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Male; Phosphorylation; Proteasome Endopeptidase Complex; Semen; Serine; Sperm Capacitation; Spermatozoa; Swine; Threonine; Tyrosine; Ubiquitins | 2022 |
The protein phosphatase 2A catalytic subunit StPP2Ac2b enhances susceptibility to Phytophthora infestans and senescence in potato.
Topics: Catalytic Domain; Disease Resistance; Hormones; Phytophthora infestans; Plant Diseases; Plants, Genetically Modified; Protein Phosphatase 2; Serine; Solanum tuberosum; Threonine | 2022 |
Sexual dimorphism in the molecular mechanisms of insulin resistance during a critical developmental window in Wistar rats.
Topics: Animals; Blood Glucose; Female; Glucose; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Sex Characteristics; Threonine | 2022 |
Sequence Characteristics and Expression Analysis of
Topics: Abscisic Acid; Amino Acids; Calcineurin; Gene Expression Regulation, Plant; Gossypium; Phylogeny; Plant Breeding; Plant Growth Regulators; Plant Proteins; Protein Kinases; Serine; Stress, Physiological; Threonine | 2022 |
Design of Novel IRAK4 Inhibitors Using Molecular Docking, Dynamics Simulation and 3D-QSAR Studies.
Topics: Autoimmune Diseases; Humans; Interleukin-1 Receptor-Associated Kinases; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Myeloid Differentiation Factor 88; Protein Kinase Inhibitors; Quantitative Structure-Activity Relationship; Receptors, Interleukin-1; Serine; Threonine | 2022 |
Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling.
Topics: Adipocytes; Animals; Diabetes Mellitus, Type 2; Homeostasis; Insulin; Insulin Resistance; Male; Mice; Phosphorylation; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Serine; Threonine; Tyrosine | 2022 |
Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125.
Topics: Antarctic Regions; Cold Temperature; Epileptic Syndromes; Humans; Peptide Hydrolases; Protein Kinases; Protein Serine-Threonine Kinases; Proteome; Pseudoalteromonas; Recombinant Proteins; Serine; Spasms, Infantile; Threonine | 2022 |
Subcellular partitioning of protein kinase activity revealed by functional kinome profiling.
Topics: Animals; Peptides; Phosphorylation; Protein Kinases; Rats; Serine; Subcellular Fractions; Threonine | 2022 |
Identification and expression profiling of receptor-interacting serine/threonine-protein kinase 2 in Siberian sturgeon (Acipenser baerii).
Topics: Animals; Fishes; Phylogeny; Protein Kinases; Serine; Threonine | 2023 |
In-Depth Characterization of the Clostridioides difficile Phosphoproteome to Identify Ser/Thr Kinase Substrates.
Topics: Bacterial Proteins; Clostridioides; Clostridioides difficile; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proteome; Serine; Threonine | 2022 |
Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury.
Topics: Acetaminophen; Adaptor Proteins, Signal Transducing; Animals; Chemical and Drug Induced Liver Injury; Mice; Nuclear Proteins; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Serine; Threonine; YAP-Signaling Proteins | 2022 |
Brain O-GlcNAcylation: From Molecular Mechanisms to Clinical Phenotype.
Topics: Acetylglucosamine; Brain; Monosaccharides; Phenotype; Serine; Threonine | 2023 |
Accurately predicting microbial phosphorylation sites using evolutionary and structural features.
Topics: Amino Acid Sequence; Computational Biology; Phosphorylation; Protein Processing, Post-Translational; Serine; Software; Threonine | 2023 |
Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancer.
Topics: Cell Cycle Proteins; Humans; Male; Neoplasms; Retinoblastoma Protein; Serine; Threonine; Transcription Factors | 2022 |
Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.
Topics: Animals; COVID-19; Glycogen Synthase Kinase 3; Humans; Mammals; Nucleocapsid; Nucleocapsid Proteins; Phosphorylation; Protein Serine-Threonine Kinases; SARS-CoV-2; Serine; Threonine; Virus Replication | 2022 |
Identification of serine/threonine kinases that regulate metabolism and sporulation in Clostridium beijerinckii.
Topics: 1-Butanol; Butanols; Clostridium; Clostridium beijerinckii; Ethanol; Fermentation; Protein Serine-Threonine Kinases; Serine; Threonine | 2022 |
Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study.
Topics: Amino Acids; Animals; Coronary Artery Disease; Fatty Acids; Glycine; Liver; Metabolomics; Myocardial Ischemia; Purines; Rats; Rats, Sprague-Dawley; Serine; Threonine | 2022 |
Comprehensive In Silico Functional Prediction Analysis of CDKL5 by Single Amino Acid Substitution in the Catalytic Domain.
Topics: Amino Acid Substitution; Catalytic Domain; Cyclin-Dependent Kinases; Mutation, Missense; Serine; Threonine | 2022 |
Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns.
Topics: Alanine; Amino Acids; Animals; Antihypertensive Agents; Antioxidants; Aspartic Acid; Cucurbitaceae; Glycine; Hypertension; Phenylalanine; Plant Extracts; Rats; Rats, Inbred Dahl; Renal Insufficiency; Serine; Sodium Chloride; Sodium Chloride, Dietary; Threonine; Tyrosine | 2022 |
Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation.
Topics: Animals; Apoptosis; Inflammation; Mice; Phosphorylation; Protein Kinases; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 2022 |
Investigation of in vitro histone H3 glycosylation using H3 tail peptides.
Topics: Acetylglucosamine; Glycosylation; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; N-Acetylglucosaminyltransferases; Peptides; Protein Processing, Post-Translational; Serine; Threonine | 2022 |
Alteration in tyrosine phosphorylation of cardiac proteome and EGFR pathway contribute to hypertrophic cardiomyopathy.
Topics: Animals; Cardiomegaly; Cardiomyopathy, Hypertrophic; Mice; Phosphorylation; Proteome; Serine; Threonine; Tyrosine | 2022 |
The Integration of Proteome-Wide PTM Data with Protein Structural and Sequence Features Identifies Phosphorylations that Mediate 14-3-3 Interactions.
Topics: 14-3-3 Proteins; Binding Sites; Fetal Proteins; Humans; Machine Learning; Mitogen-Activated Protein Kinase 7; Phosphorylation; Protein Interaction Maps; Protein-Tyrosine Kinases; Proteome; Serine; Threonine | 2023 |
Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12.
Topics: Esters; Serine; Threonine; Ubiquitin | 2022 |
Identification of highly specific antibodies for Serine/threonine-protein kinase TBK1 for use in immunoblot, immunoprecipitation and immunofluorescence.
Topics: Antibodies; Fluorescent Antibody Technique; Immunoprecipitation; Mutation; Protein Serine-Threonine Kinases; Serine; Threonine | 2022 |
Cytotoxicity of a Novel Compound Produced in Foods via the Reaction of Amino Acids with Acrolein along with Formaldehyde.
Topics: Acrolein; Aldehydes; Amino Acids; Formaldehyde; gamma-Aminobutyric Acid; Humans; Serine; Threonine | 2022 |
Characterization of thermostable serine hydroxymethyltransferase for β-hydroxy amino acids synthesis.
Topics: Amino Acids; Glycine Hydroxymethyltransferase; Serine; Threonine | 2023 |
Evolutionary divergence in the conformational landscapes of tyrosine vs serine/threonine kinases.
Topics: Molecular Dynamics Simulation; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Serine; Threonine; Tyrosine | 2022 |
[Preliminary exploration of the metabolic profile and metabolic pathways in newly diagnosed multiple myeloma].
Topics: Adult; Aged; Biomarkers; Cysteine; Female; Humans; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Methionine; Middle Aged; Multiple Myeloma; Phenylalanine; Reproducibility of Results; Serine; Threonine | 2022 |
Metabolic pathway analysis of hyperuricaemia patients with hyperlipidaemia based on high-throughput mass spectrometry: a case‒control study.
Topics: Alanine; Aspartic Acid; Biomarkers; Case-Control Studies; Glycine; Humans; Hyperlipidemias; Hyperuricemia; Linoleic Acid; Mass Spectrometry; Metabolic Diseases; Metabolic Networks and Pathways; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Heat Capacities of L-Cysteine, L-Serine, L-Threonine, L-Lysine, and L-Methionine.
Topics: Cysteine; Hot Temperature; Lysine; Methionine; Serine; Threonine | 2023 |
Nutritional geometry framework of sleep.
Topics: Animals; Diet; Diet, Protein-Restricted; Dietary Carbohydrates; Dietary Proteins; Drosophila; Female; Glucose; Glycine; Glycogen; Male; Serine; Sleep; Threonine | 2023 |
Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia.
Topics: Animals; Apoptosis; Cell Line, Tumor; Dasatinib; DNA; DNA-Activated Protein Kinase; Leukemia, Myeloid, Acute; Mice; Mutation; Protein Kinase Inhibitors; Receptor Protein-Tyrosine Kinases; Serine; Signal Transduction; Threonine; TOR Serine-Threonine Kinases; Tyrosine | 2023 |
Comparative multi-tissue analyses identify testis-specific serine/threonine protein kinase (TSSK) genes involved in male fertility in the melon fly Zeugodacus cucurbitae.
Topics: Animals; Cucurbitaceae; Fertility; Male; Protein Kinases; Seeds; Serine; Tephritidae; Testis; Threonine | 2023 |
Understanding the mechanism of twenty-five ingredient decoction for setting a fracture in the treatment of fractures based on network pharmacology.
Topics: Cyclin-Dependent Kinases; Databases, Genetic; Drugs, Chinese Herbal; Humans; Interleukin-6; Medicine, Chinese Traditional; Network Pharmacology; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Serine; Threonine; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2023 |
Nutritional geometry framework of sucrose taste in Drosophila.
Topics: Animals; Carbohydrates; Dietary Proteins; Drosophila; Female; Male; Serine; Sucrose; Taste; Taste Perception; Threonine | 2023 |
Embryonic poly(A)-binding protein interacts with translation-related proteins and undergoes phosphorylation on the serine, threonine, and tyrosine residues in the mouse oocytes and early embryos.
Topics: Animals; Humans; Mice; Oocytes; Phosphorylation; Poly(A)-Binding Proteins; Serine; Threonine; Tyrosine | 2023 |
Metabolic Mechanism of
Topics: Bacillus; Glycine; Metabolomics; Serine; Threonine | 2023 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Metabolic perturbations in pregnant rats exposed to low-dose perfluorooctanesulfonic acid: An integrated multi-omics analysis.
Topics: Animals; Female; Fluorocarbons; Glycine; Multiomics; Pregnancy; Rats; Rats, Sprague-Dawley; Serine; Steroids; Threonine | 2023 |
An LTR retrotransposon insertion inside CsERECTA for an LRR receptor-like serine/threonine-protein kinase results in compact (cp) plant architecture in cucumber.
Topics: Arabidopsis; Cucumis sativus; Gene Expression Regulation, Plant; Phenotype; Plant Breeding; Plant Proteins; Protein Kinases; Retroelements; Serine; Terminal Repeat Sequences; Threonine | 2023 |
The Majority of the Serine/Threonine Phosphorylation Sites in Bcl11b Protein Are Dispensable for the Differentiation of T Cells.
Topics: Animals; Cell Differentiation; Mice; Phosphorylation; Protein Processing, Post-Translational; Repressor Proteins; Serine; Threonine; Transcription Factors; Tumor Suppressor Proteins | 2023 |
Synthesis of Disulfide Surrogate Peptides through a Serine/Threonine Ligation-Assisted Diaminodiacid Strategy.
Topics: Disulfides; Peptides; Serine; Threonine | 2023 |
Serine Threonine-Protein Kinase-Derived IW13 Improves Lipid Metabolism via C/EBP-α/SREBP1/FAS Signaling Pathways in HFD-Induced Zebrafish In Vivo Larval Model.
Topics: Animals; Antioxidants; CCAAT-Enhancer-Binding Protein-alpha; Diabetes Mellitus, Type 2; Lipid Metabolism; Obesity; Oxidative Stress; Protein Kinases; Serine; Signal Transduction; Threonine; Zebrafish | 2023 |
Standardized ileal digestibility of amino acids in cottonseed meal fed to pregnant and non-pregnant sows.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Cottonseed Oil; Cysteine; Diet; Digestion; Female; Glycine max; Ileum; Methionine; Pregnancy; Serine; Swine; Threonine; Tyrosine | 2023 |
RACK1 release from the Ribosome Couples Translational Regulation with Starving Signaling and Possibly Depends on Phosphorylation of Key Serine and Threonine Residues.
Topics: Phosphorylation; Protein Biosynthesis; Serine; Signal Transduction; Threonine | 2023 |
Efficient production of natural sunscreens shinorine, porphyra-334, and mycosporine-2-glycine in Saccharomyces cerevisiae.
Topics: Amino Acids; Cyanobacteria; Glycine; Saccharomyces cerevisiae; Serine; Sunscreening Agents; Threonine | 2023 |
AS160 expression, but not AS160 Serine-588, Threonine-642, and Serine-704 phosphorylation, is essential for elevated insulin-stimulated glucose uptake by skeletal muscle from female rats after acute exercise.
Topics: Animals; Female; Glucose; Glucose Transporter Type 4; GTPase-Activating Proteins; Hyperinsulinism; Insulin; Male; Muscle, Skeletal; Phosphorylation; Physical Conditioning, Animal; Rats; Serine; Threonine | 2023 |
Study on the mechanism of Baihe Dihuang decoction in treating menopausal syndrome based on network pharmacology.
Topics: Drugs, Chinese Herbal; ErbB Receptors; Estrogen Receptor alpha; Female; Humans; Medicine, Chinese Traditional; Menopause; Molecular Docking Simulation; Network Pharmacology; Proto-Oncogene Proteins c-akt; Serine; Threonine; Tumor Suppressor Protein p53 | 2023 |
The triglyceride catabolism regulated by a serine/threonine protein phosphatase, Smek1, is required for development and plant infection in Magnaporthe oryzae.
Topics: Arabinose; Carbon; Fatty Acids; Fungal Proteins; Gene Expression Regulation, Fungal; Glucose; Glycerol; Glyoxylates; Lipids; Lipolysis; Magnaporthe; Oryza; Phosphoprotein Phosphatases; Plant Diseases; Serine; Spores, Fungal; Threonine | 2023 |
Pharmacokinetics of the Akt Serine/Threonine Protein Kinase Inhibitor, Capivasertib, Administered to Healthy Volunteers in the Presence and Absence of the CYP3A4 Inhibitor Itraconazole.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Healthy Volunteers; Humans; Itraconazole; Middle Aged; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Serine; Threonine | 2023 |
Oxidation and Phenolysis of Peptide/Protein C-Terminal Hydrazides Afford Salicylaldehyde Ester Surrogates for Chemical Protein Synthesis.
Topics: Cysteine; Esters; Peptides; Protein C; Proteins; Serine; Threonine | 2023 |
Expression of Testis-specific Serine/Threonine Kinases during the Reproductive and Nonreproductive Seasons and Their Localization in Mature Spermatozoa of Tree Shrews (
Topics: Animals; Male; Protein Serine-Threonine Kinases; RNA, Messenger; Seasons; Semen; Serine; Shrews; Spermatozoa; Testis; Threonine; Tupaia; Tupaiidae | 2023 |
An Inherent Difference between Serine and Threonine Phosphorylation: Phosphothreonine Strongly Prefers a Highly Ordered, Compact, Cyclic Conformation.
Topics: Amino Acids; Phosphorylation; Phosphothreonine; Serine; Threonine | 2023 |
Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring.
Topics: Alanine; Animals; Aspartic Acid; Cytochrome P-450 Enzyme System; Female; Gene Expression Profiling; Glycine; Lactation; Lipid Metabolism; Metabolomics; Pantetheine; Phosphates; Pregnancy; Rats; Serine; Threonine; Transcriptome; Xenobiotics | 2023 |
Quizartinib inhibits necroptosis by targeting receptor-interacting serine/threonine protein kinase 1.
Topics: Animals; Mice; Necroptosis; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Necrosis Factor-alpha | 2023 |
The C-terminal domain of the antiamyloid chaperone DNAJB6 binds to amyloid-β peptide fibrils and inhibits secondary nucleation.
Topics: Amyloid; Amyloid beta-Peptides; HSP40 Heat-Shock Proteins; Humans; Molecular Chaperones; Nerve Tissue Proteins; Peptide Fragments; Protein Binding; Serine; Threonine | 2023 |
The Role of Serine/Threonine-Specific Protein Kinases in Cyanobacteria - SpkB Is Involved in Acclimation to Fluctuating Conditions in Synechocystis sp. PCC 6803.
Topics: Acclimatization; Bacterial Proteins; Mutation; Protein Serine-Threonine Kinases; Proteome; Serine; Synechocystis; Threonine | 2023 |
[Effects and mechanisms of total flavones of Abelmoschus manihot in inhibiting podocyte necroptosis and renal fibrosis in diabetic kidney disease].
Topics: Abelmoschus; Animals; Collagen; Diabetes Mellitus; Diabetic Nephropathies; Fibrosis; Flavones; Humans; Necroptosis; Podocytes; Rats; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Necrosis Factor-alpha | 2023 |
Assessment of the anti-inflammatory mechanism of quercetin 3,7-dirhamnoside using an integrated pharmacology strategy.
Topics: Anti-Inflammatory Agents; Drugs, Chinese Herbal; Flavonoids; Ligands; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases; Quercetin; Serine; Threonine; TOR Serine-Threonine Kinases | 2023 |
Differential tyrosine and serine/threonine phosphorylation/dephosphorylation pathways regulate the expression of α7 versus α3β4 nicotinic receptor subtypes in mouse hippocampal neurons.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Hippocampus; Humans; Mice; Neurons; Phosphorylation; Protein Tyrosine Phosphatases; Receptors, Nicotinic; Serine; Threonine; Tyrosine | 2023 |
Antibody-Proteolysis Targeting Chimera Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 in HER2+ Cell Lines.
Topics: Cell Line; Immunoconjugates; Proteolysis; Proteolysis Targeting Chimera; Serine; Threonine; Ubiquitin-Protein Ligases | 2023 |
Detection and identification of amino acids and proteins using their intrinsic fluorescence in the visible light spectrum.
Topics: Alanine; Amino Acids; Arginine; Cystine; Fluorescence; Glycine; Leucine; Methionine; Proteins; Serine; Threonine; Tyrosine; Valine | 2023 |
[Characterization the response of
Topics: Carbon; Chlamydomonas reinhardtii; Photosynthesis; Plants; Protein Kinases; Serine; Threonine | 2023 |
Identification and validation of major-effect quantitative trait locus QMS-5B associated with male sterility in photo-thermo-sensitive genic male sterile wheat.
Topics: Humans; Infertility, Male; Male; Protein Serine-Threonine Kinases; Quantitative Trait Loci; Serine; Threonine; Triticum | 2023 |
Metabolic alterations unravel the maternofetal immune responses with disease severity in pregnant women infected with SARS-CoV-2.
Topics: COVID-19; Cytokines; Female; Glycine; Humans; Immunity; Infant, Newborn; Interferon-alpha; Interleukin-6; Interleukin-9; Lactates; NAD; Patient Acuity; Pregnancy; Pregnant Women; Pyruvates; Riboflavin; SARS-CoV-2; Serine; Threonine | 2023 |
Advancing the accuracy of SARS-CoV-2 phosphorylation site detection via meta-learning approach.
Topics: COVID-19; Humans; Phosphorylation; SARS-CoV-2; Serine; Threonine | 2023 |