threonine has been researched along with piperidines in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bonn, G; Fiechtner, B; Glossmann, H; Huck, CW; Moebius, FF; Soellner, KE | 1 |
| Bryckaert, M; Contreres, JO; Dupuy, E; Habib, A; Herbert, JM; Job, B; Levy-Toledano, S; Rosa, JP; Savi, P; Simoneau, G | 1 |
| Clark, S; Leever, JD; Partin, KM; Weeks, AM | 1 |
| Fukui, R; Higashi, H; Matsuyama, S; Nishi, A | 1 |
| Ahn, KH; D'Antona, AM; Kendall, DA | 1 |
| He, D; Liu, F; Matsuura, I; Wang, G | 1 |
| Dow, EC; Liu, H; Rice, AP | 1 |
| Doucette, CD; Hilchie, AL; Hoskin, DW; Liwski, R | 1 |
| Bergmeier, SC; Boyd, RT; González-Cestari, TF; Henderson, BJ; Li, C; McKay, DB; Pavlovicz, RE; Yi, B | 1 |
| Dai, B; Fang, B; Gao, W; Gold, KA; Heymach, JV; Hofstetter, WL; Lu, H; Minna, J; Ou, Z; Roth, JA; Swisher, SG; Wang, L; Wang, M; Wu, S; Zhang, L | 1 |
| Ali, SM; Busaidy, NL; Chmielecki, J; Elvin, JA; Erlich, RL; Heilmann, AM; Khan, SA; Lipson, D; Miller, VA; Murthy, R; Nangia, C; Ross, JS; Shah, MH; Sherman, SI; Stephens, PJ; Subbiah, I; Subbiah, V; Sun, JX; Vergilio, JA; Wang, K; Yelensky, R | 1 |
| Berglöf, A; Blomberg, KE; Hamasy, A; Mohammad, DK; Smith, CI; Vihinen, M; Wang, Q; Yu, L | 1 |
| Belmont, LD; Bergeron, P; Bowman, K; Burton, L; Choy, R; Crawford, JJ; Eigenbrot, C; Estevez, A; Franke, Y; Gogol, E; Johnson, AR; Katewa, A; Kohli, PB; Li, H; Lin, M; Mortara, K; Ortwine, DF; Penuel, E; Tam, C; Wu, J; Young, WB; Yu, C | 1 |
| Gobec, S; Grabrijan, K; Jukič, M; Kadić, S; Lera Garrido, FJ; Obreza, A; Sosič, I | 1 |
| Berglöf, A; Estupiñán, HY; Mohammad, DK; Schaafsma, GCP; Shi, Y; Smith, CIE; Vihinen, M; Wang, Q; Yu, L; Zain, R; Zhou, L | 1 |
15 other study(ies) available for threonine and piperidines
| Article | Year |
|---|---|
Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Asparagine; Carrier Proteins; Cell Membrane; Glutamic Acid; Histidine; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Piperidines; Saccharomyces cerevisiae; Steroid Isomerases; Threonine; Tryptophan | 1999 |
Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
Topics: Adenosine Diphosphate; Adolescent; Adult; Benzylamines; Blood Platelets; Clopidogrel; Electrophoresis, Polyacrylamide Gel; Humans; Male; Membrane Proteins; Phosphorylation; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Serine; Signal Transduction; Thiazoles; Thionucleotides; Threonine; Ticlopidine; Tyrosine | 2003 |
Identification of a site in GluR1 and GluR2 that is important for modulation of deactivation and desensitization.
Topics: Amino Acid Substitution; Animals; Benzothiadiazines; Binding Sites; Dioxoles; Glutamic Acid; Kinetics; Models, Molecular; Oocytes; Piperidines; Point Mutation; Receptors, AMPA; Serine; Threonine; Transfection; Xenopus laevis | 2003 |
Regulation of DARPP-32 Thr75 phosphorylation by neurotensin in neostriatal neurons: involvement of glutamate signalling.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Benzazepines; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Histamine H1 Antagonists; Immunoblotting; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Neostriatum; Nerve Tissue Proteins; Neurons; Neurotensin; Phosphoproteins; Piperidines; Pyrazoles; Quinolines; Raclopride; Receptors, Neurotensin; Signal Transduction; Tetrodotoxin; Threonine; Time Factors | 2003 |
Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arachidonic Acids; Benzoxazines; Cells, Cultured; Cyclic AMP; Dronabinol; Drug Stability; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Humans; Kidney; Ligands; Morpholines; Mutation; Naphthalenes; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Threonine | 2006 |
Transforming growth factor-{beta}-inducible phosphorylation of Smad3.
Topics: Animals; Cell Line, Tumor; Fibroblasts; Flavonoids; Humans; Ligands; Mice; Mink; Models, Biological; Mutation; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Smad3 Protein; Threonine; Transforming Growth Factor beta | 2009 |
T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes.
Topics: CD4-Positive T-Lymphocytes; Cell Cycle Proteins; Cell Nucleus; Cyclin T; Cyclin-Dependent Kinase 9; Flavonoids; HeLa Cells; Humans; Microscopy, Fluorescence; Multienzyme Complexes; Mutation; Nuclear Proteins; Phosphorylation; Piperidines; Positive Transcriptional Elongation Factor B; Protein Kinase Inhibitors; Protein Multimerization; Protein Transport; Recombinant Fusion Proteins; Ribonucleoproteins, Small Nuclear; RNA Polymerase II; RNA-Binding Proteins; Threonine; Transcription Factors; Transcription, Genetic; Transfection | 2010 |
Piperine, a dietary phytochemical, inhibits angiogenesis.
Topics: Alkaloids; Angiogenesis Inhibitors; Animals; Aorta; Benzodioxoles; Breast Neoplasms; Cell Movement; Cell Proliferation; Chick Embryo; Chromones; Drug Screening Assays, Antitumor; Female; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Morpholines; Neovascularization, Pathologic; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-akt; Rats, Wistar; S Phase; Serine; Threonine; TRPV Cation Channels | 2013 |
Defining the putative inhibitory site for a selective negative allosteric modulator of human α4β2 neuronal nicotinic receptors.
Topics: Binding Sites; Biphenyl Compounds; Calcium; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neurons; Nicotinic Antagonists; Phenylalanine; Piperidines; Receptors, Nicotinic; Structure-Activity Relationship; Threonine | 2012 |
Selective antitumor activity of ibrutinib in EGFR-mutant non-small cell lung cancer cells.
Topics: Adenine; Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Methionine; Mice; Mutation; Piperidines; Pyrazoles; Pyrimidines; Quinazolines; Threonine | 2014 |
Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma.
Topics: Aged; Anilides; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Drug Resistance, Neoplasm; Everolimus; Female; Fibroblast Growth Factor 3; Fibroblast Growth Factors; Gene Amplification; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Methionine; Middle Aged; Molecular Targeted Therapy; Mutation; Piperidines; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Pyridines; Quinazolines; Threonine; Thyroid Neoplasms | 2016 |
Substitution scanning identifies a novel, catalytically active ibrutinib-resistant BTK cysteine 481 to threonine (C481T) variant.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Amino Acid Substitution; Animals; Biocatalysis; Cell Line; Cysteine; Drug Resistance, Neoplasm; Humans; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Threonine; Transfection | 2017 |
Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Agents; Cysteine; Humans; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Mutation; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Threonine | 2016 |
Chlorocarbonylsulfenyl Chloride Cyclizations Towards Piperidin-3-yl-oxathiazol-2-ones as Potential Covalent Inhibitors of Threonine Proteases.
Topics: Cyclization; Piperidines; Protease Inhibitors; Thiazoles; Threonine | 2017 |
BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Benzamides; Cell Line; Cell Line, Tumor; Chickens; Chlorocebus aethiops; COS Cells; Cysteine; Drug Resistance, Neoplasm; HEK293 Cells; Humans; Mutation; Piperidines; Protein Kinase Inhibitors; Pyrazines; Pyrazoles; Pyrimidines; Threonine | 2021 |