Compounds > threonine

threonine and paclitaxel

threonine has been researched along with paclitaxel in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's9 (69.23)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chau, MS; Hunter, T; Poon, RY; Yamashita, K1
Ichijo, H; Korsmeyer, SJ; Yamamoto, K1
Pietenpol, JA; Stewart, ZA; Tang, LJ1
Horwitz, SB; Yang, CP1
Bast, RC; Hittelman, WN; Le, XF; Li, C; Liu, J; McWatters, A; Mills, GB1
Craig, RW; Domina, AM; Gregory, MA; Hann, SR; Vrana, JA1
Scaife, RM1
Adachi, S; Itamochi, H; Sudo, T; Takahashi, T; Tamamori-Adachi, M; Ueno, NT; Yamasaki, F1
Audoynaud, C; Beghin, A; Bertholon, J; Bouchet, BP; Dumontet, C; Falette, N; Galmarini, CM; Lamblot, C; Puisieux, A; Wang, Q1
Andreu, JM; Barasoain, I; Buey, RM; Calvo, E; Cerezo, G; Day, BW; Díaz, JF; Edler, MC; Hamel, E; López, JA; Matesanz, R; Pineda, O; Sorensen, EJ; Vanderwal, CD1
Buscemi, G; Carlessi, L; Delia, D; Hong, Z; Larson, G; Wu, JZ1
Ahmed, AA; Bast, RC; Claret, FX; He, G; Hung, MC; Le, XF; Mao, W; Siddik, ZH; Xia, W1
Hayes, DF; Henry, NL; Hertz, DL; Kim, JH; Smith, EML; Stringer, KA; Sun, Y; Vangipuram, K; Yeomans, L1

Other Studies

13 other study(ies) available for threonine and paclitaxel

ArticleYear
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells.
    Cancer research, 1997, Nov-15, Volume: 57, Issue:22

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Caffeine; CDC2 Protein Kinase; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; Doxorubicin; Electrophoresis, Polyacrylamide Gel; G1 Phase; G2 Phase; Humans; Mice; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Protein Kinases; Threonine; Tumor Cells, Cultured; Tyrosine

1997
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.
    Molecular and cellular biology, 1999, Volume: 19, Issue:12

    Topics: Amino Acid Sequence; Apoptosis; Binding Sites; CDC2 Protein Kinase; Cyclin B; Cyclin B1; Enzyme Activation; G2 Phase; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 7; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Microtubules; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitosis; Molecular Sequence Data; Mutagenesis; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Serine; Threonine

1999
Increased p53 phosphorylation after microtubule disruption is mediated in a microtubule inhibitor- and cell-specific manner.
    Oncogene, 2001, Jan-04, Volume: 20, Issue:1

    Topics: Antineoplastic Agents; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Humans; Microtubules; Mutagenesis, Site-Directed; Paclitaxel; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Vincristine

2001
Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells.
    Biochimica et biophysica acta, 2002, Jun-12, Volume: 1590, Issue:1-3

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Antineoplastic Agents, Phytogenic; Butadienes; Cell Line; Enzyme Inhibitors; Gene Expression; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Proteins; Pyridines; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Threonine; Tumor Necrosis Factor-alpha

2002
Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis.
    Oncogene, 2003, Jan-30, Volume: 22, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Calcium; Humans; Isoenzymes; Mitogen-Activated Protein Kinases; Mitosis; Paclitaxel; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Type C Phospholipases

2003
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol.
    Oncogene, 2004, Jul-08, Volume: 23, Issue:31

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Carcinogens; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Okadaic Acid; Paclitaxel; Peptide Mapping; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection

2004
G2 cell cycle arrest, down-regulation of cyclin B, and induction of mitotic catastrophe by the flavoprotein inhibitor diphenyleneiodonium.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:10

    Topics: Animals; Antioxidants; Apoptosis; Aurora Kinase A; Aurora Kinases; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Centrosome; Chromatids; Cyclin B; Cyclin B1; DNA; Down-Regulation; Enzyme Inhibitors; Flavoproteins; Flow Cytometry; G2 Phase; Humans; MAP Kinase Signaling System; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Mitosis; NIH 3T3 Cells; Onium Compounds; Paclitaxel; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Reactive Oxygen Species; Spindle Apparatus; Threonine; Time Factors; Xenopus Proteins

2004
Cyclin A-associated kinase activity is needed for paclitaxel sensitivity.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; CDC2 Protein Kinase; Cyclin A; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Female; Humans; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Threonine; Transfection; Tumor Cells, Cultured

2005
A p21/WAF1 mutation favors the appearance of drug resistance to paclitaxel in human noncancerous epithelial mammary cells.
    International journal of cancer, 2006, Jul-01, Volume: 119, Issue:1

    Topics: Amino Acid Sequence; Antineoplastic Agents, Phytogenic; Base Pair Mismatch; Blotting, Western; Codon; Cyclin-Dependent Kinase Inhibitor p21; Drug Resistance; Epithelial Cells; Female; Gene Expression Regulation; Gene Silencing; Genes, MDR; Humans; Mammary Glands, Human; Molecular Sequence Data; Paclitaxel; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Radiation Dosage; Radiation, Ionizing; Threonine

2006
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
    Nature chemical biology, 2007, Volume: 3, Issue:2

    Topics: Alkanes; Amino Acid Sequence; Asparagine; Binding Sites; Binding, Competitive; Carbamates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Docetaxel; Epothilones; Humans; Inhibitory Concentration 50; Lactones; Mass Spectrometry; Microtubules; Models, Chemical; Models, Molecular; Molecular Sequence Data; Paclitaxel; Polycyclic Compounds; Protein Binding; Pyrones; Taxoids; Threonine; Tubulin; Tubulin Modulators

2007
Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Benzimidazoles; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cells, Cultured; Checkpoint Kinase 1; Checkpoint Kinase 2; Cisplatin; DNA Damage; DNA-Binding Proteins; Doxorubicin; Enzyme Inhibitors; Humans; Immunoprecipitation; Mice; Molecular Structure; Paclitaxel; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Radiation, Ionizing; Recombinant Proteins; Serine; Thiazoles; Threonine; Tumor Suppressor Proteins

2007
The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.
    Journal of the National Cancer Institute, 2011, Sep-21, Volume: 103, Issue:18

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Confounding Factors, Epidemiologic; Cyclin-Dependent Kinase Inhibitor p27; Dasatinib; Drug Synergism; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, bcl-1; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Research Design; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Serine; src-Family Kinases; Thiazoles; Threonine; Tyrosine; Xenograft Model Antitumor Assays

2011
Pharmacometabolomics reveals a role for histidine, phenylalanine, and threonine in the development of paclitaxel-induced peripheral neuropathy.
    Breast cancer research and treatment, 2018, Volume: 171, Issue:3

    Topics: Adult; Aged; Biomarkers; Breast Neoplasms; Female; Histidine; Humans; Magnetic Resonance Spectroscopy; Metabolomics; Middle Aged; Paclitaxel; Peripheral Nervous System Diseases; Phenylalanine; Threonine

2018