Compounds > threonine

threonine and naloxone

threonine has been researched along with naloxone in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
George, SR; O'Dowd, BF; Pak, Y1
George, SR; O'Dowd, BF; Pak, Y; Wang, JB1
Wang, HL1
Chen, C; Huang, P; Li, J; Liu-Chen, LY; Visiers, I; Weinstein, H1
Fukazawa, Y; Gao, Y; Hamabe, W; Kishioka, S; Kumamoto, K; Maeda, T; Ozaki, M1

Other Studies

5 other study(ies) available for threonine and naloxone

ArticleYear
Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail.
    The Journal of biological chemistry, 1997, Oct-03, Volume: 272, Issue:40

    Topics: Alanine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Point Mutation; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection

1997
Agonist-induced, G protein-dependent and -independent down-regulation of the mu opioid receptor. The receptor is a direct substrate for protein-tyrosine kinase.
    The Journal of biological chemistry, 1999, Sep-24, Volume: 274, Issue:39

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; CHO Cells; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; GTP-Binding Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Pertussis Toxin; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Rats; Receptors, Opioid, mu; Recombinant Proteins; Threonine; Transfection; Virulence Factors, Bordetella

1999
A cluster of Ser/Thr residues at the C-terminus of mu-opioid receptor is required for G protein-coupled receptor kinase 2-mediated desensitization.
    Neuropharmacology, 2000, Jan-28, Volume: 39, Issue:3

    Topics: Analgesics, Opioid; Animals; beta-Adrenergic Receptor Kinases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; G-Protein-Coupled Receptor Kinase 2; Humans; Naloxone; Narcotic Antagonists; Rats; Receptors, Opioid, mu; Serine; Threonine; Transfection

2000
Functional role of a conserved motif in TM6 of the rat mu opioid receptor: constitutively active and inactive receptors result from substitutions of Thr6.34(279) with Lys and Asp.
    Biochemistry, 2001, Nov-13, Volume: 40, Issue:45

    Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Aspartic Acid; CHO Cells; Conserved Sequence; Cricetinae; Diprenorphine; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Lysine; Models, Molecular; Naloxone; Narcotic Antagonists; Pertussis Toxin; Rats; Receptors, Opioid, mu; Sulfur Radioisotopes; Threonine; Tritium; Virulence Factors, Bordetella

2001
Morphine has an antinociceptive effect through activation of the okadaic-acid-sensitive Ser/Thr protein phosphatases PP 2 A and PP5 estimated by tail-pinch test in mice.
    Brain research, 2005, Sep-21, Volume: 1056, Issue:2

    Topics: Animals; Area Under Curve; Blotting, Western; Brain; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Narcotics; Nuclear Proteins; Okadaic Acid; Pain; Phosphoprotein Phosphatases; Phosphorylation; Serine; Threonine; Time Factors

2005