threonine and epidermal growth factor

threonine has been researched along with epidermal growth factor in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (13.75)	18.7374
1990's	33 (41.25)	18.2507
2000's	25 (31.25)	29.6817
2010's	10 (12.50)	24.3611
2020's	1 (1.25)	2.80

Authors

Authors	Studies
Countaway, JL; Davis, RJ; Nairn, AC	1
Lentz, SR; Sadler, JE; Tsiang, M	1
Her, JH; L'Allemain, G; Sturgill, TW; Weber, MJ; Wu, J	1
Park, D; Rhee, SG	1
Artrip, J; Bottaro, DP; Di Fiore, PP; Helin, K; Kraus, MH; Pierce, JH; Segatto, O	1
Felder, S; LaVin, J; Schlessinger, J; Ullrich, A	1
Bird, TA; Saklatvala, J	1
Mendelsohn, J; Peacock, JS; Sunada, H; Yu, P	1
Abdel-Ghany, M; Koland, J; Racker, E; Revis-Gupta, S	1
Griswold-Prenner, I; Ingebritsen, T; Rosner, MR; Takishima, K	1
Guzzetta, AW; Harris, RJ; Leonard, CK; Spellman, MW	1
Countaway, JL; Davis, RJ; Gironès, N; McQuilkin, P	1
Deuel, TF; Shawver, LK	1
Decker, SJ; Ellis, C; Pawson, T; Velu, T	1
Fiol, CJ; Gill, GN; Heisermann, GJ; Ingraham, HA; Walsh, BJ; Wiley, HS	1
Miyasaka, J; Miyasaka, T; Saltiel, AR	1
Chen, WS; Gill, GN; Herbst, JJ; Lazar, CS; Lund, KA; Rosenfeld, MG; Walsh, BJ; Walton, GM; Welsh, JB; Wiley, HS	1
Friedman, BA; Fujiki, H; Rosner, MR; van Amsterdam, J	1
Abdel-Ghany, M; el Saad, MA; Kole, HK; Racker, E	1
Dobashi, K; Greene, MI; Weiner, DB	1
Czech, MP; Davis, RJ	1
Cooper, JA; Hunter, T	1
Carpenter, CD; Chen, WS; Evans, RM; Gill, GN; Lazar, CS; Lin, CR; Rosenfeld, MG	1
Cooper, JA; King, CS	1
Glaser, L; Whiteley, B	1
Bertics, PJ; Gill, GN; Santon, JB	1
Berent, E; Dull, TJ; Livneh, E; Prywes, R; Schlessinger, J; Ullrich, A	1
Chinkers, M; Garbers, DL	1
Hayashi, T; Imura, H; Inoue, G; Kono, S; Kuzuya, H; Nakao, K; Okamoto, M; Suga, J; Yamada, K; Yoshimasa, Y	1
Carbonaro-Hall, DA; Hall, FL; Williams, RT; Wu, L	1
Liu, CF; Tam, JP	1
Deng, T; Karin, M	1
Decker, SJ; Pang, L; Saltiel, AR	1
Erikson, E; Fridman, H; Granot, Y; Maller, JL; Schrier, RW; Van Putten, V; Williams, B	1
Morrison, P; Rosner, MR; Takishima, K	1
Antonny, B; Boquet, P; Chardin, P; Chaves-Olarte, E; Chavrier, P; Cussac, D; de Gunzburg, J; Flatau, G; Giry, M; Lemichez, E; Popoff, MR; Thelestam, M; von Eichel-Streiber, C	1
Chantry, A; Feinmesser, RL; Gray, K; Means, AR	1
Adomeit, A; Boehmer, A; Boehmer, FD; Graness, A; Kovalenko, M; Liebmann, C; Nürnberg, B; Steinmetzer, T; Wetzker, R	1
Dolginov, Y; Hanoch, T; Lando, Z; Michael, D; Roubini, E; Rubinfeld, H; Seger, R; Yao, Z; Yung, Y; Zharhary, D	1
Fenton, SE; Sheffield, LG	1
Boonstra, J; Rijken, PJ; van der Heyden, MA; van Hal, GJ; Verkleij, AJ	1
Tsukita, S; Yonemura, S	1
Bagowski, CP; Choidas, A; Stein-Gerlach, M; Ullrich, A	1
Campbell, DH; Daly, RJ; Sutherland, RL	1
Dolginov, Y; Hanoch, T; Lando, Z; Ridner, G; Seger, R; Yao, Z; Yung, Y; Zharhary, D	1
Deng, T; Huang, Y; Winston, BW	1
Lesslauer, W; Mary, JL; Tomás-Zuber, M	1
Chung, J; Kim, D; Kim, JW; Kim, S; Koh, H; Lee, KH	1
Kolesnick, R; Xing, HR	1
Diao, C; Hollenberg, MD; Matsubara, S; Wong, NC; Zheng, XL	1
Besner, GE; Brigstock, DR; Davis-Fleische, KM	1
Brown, MC; Terfera, DR; Turner, CE	1
Huang, YT; Hwang, JJ; Ke, FC; Lee, LT; Lee, MT; Lee, PP; Liebow, C; Lo, TB; Schally, AV	1
Bos, JL; Carter, AP; de Ruiter, ND; Kooistra, K; Maassen, JA; Ouwens, DM; Schouten, J; van Dam, H; van der Burgt, C; van der Zon, GC	1
Fowler, VM; Takemoto, DJ; Wagner, LM	1
Allan, LA; Brady, S; Clarke, PR; Magee, G; Morrice, N; Pathak, S	1
Ito, F; Takeuchi, K	1
Bagheri-Yarmand, R; Barnes, CJ; Kumar, R; Li, F; Vadlamudi, RK	1
Bao, M; Clauser, K; Conley, PB; Hart, MJ; Komuves, L; Lin, H; Nanda, N; Phillips, DR; Quertermous, T	1
Evans, DR; Guy, HI; Kotsis, DH; Serre, V; Sigoillot, FD; Sigoillot, SM	1
Cohen, MS; Shokat, KM; Taunton, J; Zhang, C	1
Brunet, A; David-Dufilho, M; Millanvoye-Van Brussel, E; Rendu, F; Topal, G; Walch, L	1
Fukushi, S; Kurane, I; Mizutani, T; Morikawa, S; Saijo, M	1
Suzuki, K; Takahashi, K	1
Bellamy, A; Hait, NC; Kordula, T; Milstien, S; Spiegel, S	1
Ge, C; Haltiwanger, RS; Hou, X; Luo, Y; Shi, S; Stanley, P	1
Grøsvik, H; Huitfeldt, HS; Lindeman, B; Oksvold, MP; Rosseland, CM; Skarpen, E; Wierød, L	1
Kawanishi, M; Koizumi, K; Nishimura, M; Saiki, I; Sakurai, H; Shin, MS; Singhirunnusorn, P; Suzuki, S	1
Fuks, Z; Haimovitz-Friedman, A; Kolesnick, R; Yin, X; Zafrullah, M	1
Bode, AM; Dong, Z; Li, T; Li, X; Liu, K; Ma, W; Peng, C; Shi, G; Wen, W; Zhang, J; Zhu, F; Zykova, T	1
Bartke, A; Díaz, ME; González, L; Martínez, CS; Miquet, JG; Sotelo, AI; Turyn, D	1
Frijns, E; Jalink, K; Kuikman, I; Litjens, S; Ports, M; Raspe, M; Sonnenberg, A; Wilhelmsen, K	1
Chaudhuri, R; Humphrey, SJ; James, DE; Ma, X; Parker, BL; Peterman, S; Yang, G	1
Hawke, DH; Lee, JH; Li, X; Lu, Z; Lyu, J; Qian, X; Wang, Y; Xia, Y; Zhang, G; Zheng, Y	1
Sonnenberg, A; Te Molder, L	1
Gao, S; Huang, J; Sixt, KM; Tripathi, V; Weigert, R; Xu, X; Zhang, YE; Zhou, M	1
Boukalova, S; Chvojka, S; Macikova, L; Vlachova, V; Vyklicka, L	1
Boveris, A; Buchholz, B; Gelpi, RJ; Helfenberger, KE; Poderoso, C; Poderoso, JJ; Villalba, NM	1
Gong, J; Kong, D; Liang, Y; Nie, Y; Teng, CB; Yang, L; Yu, W; Zhu, Y	1
Chen, G; Cho, YC; Kim, H; Kim, K; Lee, HJ; Shen, Y; Zhou, R	1

Reviews

2 review(s) available for threonine and epidermal growth factor

Article	Year
Protein-tyrosine kinases. Annual review of biochemistry, 1985, Volume: 54 Topics: Amino Acid Sequence; Animals; Binding Sites; Epidermal Growth Factor; ErbB Receptors; Humans; Lipid Metabolism; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, Cell Surface; Retroviridae; Serine; Substrate Specificity; Threonine; Tyrosine; Viral Proteins	1985
Epidermal growth factor and its receptor. Molecular and cellular endocrinology, 1987, Volume: 51, Issue:3 Topics: Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Gene Amplification; Humans; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogenes; Threonine; Tyrosine	1987

Article

Year

Protein-tyrosine kinases.

Annual review of biochemistry, 1985, Volume: 54

Topics: Amino Acid Sequence; Animals; Binding Sites; Epidermal Growth Factor; ErbB Receptors; Humans; Lipid Metabolism; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, Cell Surface; Retroviridae; Serine; Substrate Specificity; Threonine; Tyrosine; Viral Proteins

1985

Epidermal growth factor and its receptor.

Molecular and cellular endocrinology, 1987, Volume: 51, Issue:3

Topics: Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Gene Amplification; Humans; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogenes; Threonine; Tyrosine

1987

Other Studies

78 other study(ies) available for threonine and epidermal growth factor

Article	Year
Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase. The Journal of biological chemistry, 1992, Jan-15, Volume: 267, Issue:2 Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Rabbits; Rats; Serine; Signal Transduction; Threonine; Tyrosine	1992
Functional domains of membrane-bound human thrombomodulin. EGF-like domains four to six and the serine/threonine-rich domain are required for cofactor activity. The Journal of biological chemistry, 1992, Mar-25, Volume: 267, Issue:9 Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Chromosome Deletion; Epidermal Growth Factor; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Conformation; Receptors, Cell Surface; Receptors, Thrombin; Restriction Mapping; Serine; Threonine; Thrombin; Transfection	1992
Growth factor-induced activation of a kinase activity which causes regulatory phosphorylation of p42/microtubule-associated protein kinase. Molecular and cellular biology, 1992, Volume: 12, Issue:5 Topics: 3T3 Cells; Amino Acid Sequence; Amino Acids; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Epidermal Growth Factor; Humans; Kinetics; Mice; Mutagenesis, Site-Directed; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Threonine; Tyrosine	1992
Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP. Molecular and cellular biology, 1992, Volume: 12, Issue:12 Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cell Line; Chromatography, Affinity; Colforsin; Cyclic AMP; Epidermal Growth Factor; Immunoblotting; Kinetics; Molecular Sequence Data; Oncogene Proteins; Organ Specificity; PC12 Cells; Phosphorylation; Precipitin Tests; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Serine; Tetradecanoylphorbol Acetate; Threonine; Type C Phospholipases	1992
A single amino acid substitution is sufficient to modify the mitogenic properties of the epidermal growth factor receptor to resemble that of gp185erbB-2. The EMBO journal, 1992, Volume: 11, Issue:11 Topics: 3T3 Cells; Amino Acid Sequence; Animals; Arginine; Base Sequence; Codon; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Genetic Vectors; Kinetics; Mice; Mitogens; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, ErbB-2; Repetitive Sequences, Nucleic Acid; Signal Transduction; Threonine; Thymidine; Transfection	1992
Kinetics of binding, endocytosis, and recycling of EGF receptor mutants. The Journal of cell biology, 1992, Volume: 117, Issue:1 Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cell Line; DNA; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Mathematics; Mice; Mutagenesis, Site-Directed; Protein Binding; Tetradecanoylphorbol Acetate; Threonine; Transfection; Up-Regulation	1992
Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654. The Journal of biological chemistry, 1990, Jan-05, Volume: 265, Issue:1 Topics: Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gingiva; Humans; Interleukin-1; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha; Tyrosine	1990
Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody. Journal of cellular physiology, 1990, Volume: 142, Issue:2 Topics: Antibodies, Monoclonal; Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Half-Life; Methylamines; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine	1990
Heparin stimulates epidermal growth factor receptor-mediated phosphorylation of tyrosine and threonine residues. Proceedings of the National Academy of Sciences of the United States of America, 1991, Jul-15, Volume: 88, Issue:14 Topics: Amino Acids; Animals; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Escherichia coli; Glutathione Transferase; Heparin; Humans; Insecta; Manganese; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Substrate Specificity; Threonine; Tyrosine	1991
Epidermal growth factor (EGF) receptor T669 peptide kinase from 3T3-L1 cells is an EGF-stimulated "MAP" kinase. Proceedings of the National Academy of Sciences of the United States of America, 1991, Mar-15, Volume: 88, Issue:6 Topics: Animals; Cell Line; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Epidermal Growth Factor; ErbB Receptors; Kinetics; Mice; Microtubule-Associated Proteins; Phosphorylation; Protein-Tyrosine Kinases; Threonine	1991
Tissue plasminogen activator has an O-linked fucose attached to threonine-61 in the epidermal growth factor domain. Biochemistry, 1991, Mar-05, Volume: 30, Issue:9 Topics: Amino Acid Sequence; Animals; Cell Line; Chromatography, High Pressure Liquid; Chymotrypsin; Epidermal Growth Factor; Fucose; Glycosylation; Humans; Melanoma; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Recombinant Proteins; Threonine; Tissue Plasminogen Activator; Trypsin	1991
Multisite phosphorylation of the epidermal growth factor receptor. Use of site-directed mutagenesis to examine the role of serine/threonine phosphorylation. The Journal of biological chemistry, 1990, Feb-25, Volume: 265, Issue:6 Topics: Amino Acid Sequence; Amino Acids; Animals; Cell Line; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Humans; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Peptide Fragments; Phosphopeptides; Phosphorylation; Plasmids; Platelet-Derived Growth Factor; Serine; Threonine; Thymidine	1990
Nuclear pp64 is phosphorylated in both serine/threonine and tyrosine through complex pathways regulated by 12-O-tetradecanoylphorbol-13-acetate and platelet-derived growth factor. Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Dimethyl Sulfoxide; Epidermal Growth Factor; Isoquinolines; Kinetics; Nuclear Proteins; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine	1990
Effects of substitution of threonine 654 of the epidermal growth factor receptor on epidermal growth factor-mediated activation of phospholipase C. The Journal of biological chemistry, 1990, Apr-25, Volume: 265, Issue:12 Topics: Animals; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Inositol Phosphates; Kinetics; Mice; Mutation; Peptide Mapping; Phosphopeptides; Phosphorylation; Plasmids; Tetradecanoylphorbol Acetate; Threonine; Transfection; Type C Phospholipases	1990
Mutational removal of the Thr669 and Ser671 phosphorylation sites alters substrate specificity and ligand-induced internalization of the epidermal growth factor receptor. The Journal of biological chemistry, 1990, Aug-05, Volume: 265, Issue:22 Topics: Amino Acid Sequence; Animals; Base Sequence; Casein Kinases; Cell Line; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Kinetics; Ligands; Mice; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Oligopeptides; Phosphorylation; Protein Kinases; Restriction Mapping; Serine; Substrate Specificity; Threonine; Transcription, Genetic; Transfection	1990
Okadaic acid stimulates the activity of microtubule associated protein kinase in PC-12 pheochromocytoma cells. Biochemical and biophysical research communications, 1990, May-16, Volume: 168, Issue:3 Topics: Adrenal Gland Neoplasms; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Epidermal Growth Factor; Ethers, Cyclic; Nerve Growth Factors; Okadaic Acid; Pheochromocytoma; Phosphorylation; Protein Kinases; Serine; Swine; Threonine; Tumor Cells, Cultured	1990
Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation. The Journal of biological chemistry, 1990, Nov-25, Volume: 265, Issue:33 Topics: Alanine; Animals; Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Ligands; Mice; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Threonine; Transfection	1990
Phosphorylation at threonine-654 is not required for negative regulation of the epidermal growth factor receptor by non-phorbol tumor promoters. Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:3 Topics: Calcimycin; Carcinogens; Cell Line; Chromatography, High Pressure Liquid; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phosphorylation; Plant Extracts; Protein-Tyrosine Kinases; Thapsigargin; Threonine; Trypsin	1989
Stimulation of phosphorylation of lipocortin at threonine residues by epidermal growth factor (EGF) and the EGF receptor: addition of protein kinase P with polylysine inhibits this effect. Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:16 Topics: Amino Acids; Annexins; Blood Platelets; Calcium; Calcium-Binding Proteins; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Molecular Weight; Phosphorylation; Polylysine; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Threonine	1989
Differential regulation of oncogenic and cellular p185 by serine/threonine kinases. DNA (Mary Ann Liebert, Inc.), 1989, Volume: 8, Issue:10 Topics: Cell Division; Cell Line; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Membrane Proteins; Mutation; Oncogene Proteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor, ErbB-2; Serine; Tetradecanoylphorbol Acetate; Threonine	1989
Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654. Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:12 Topics: Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Oncogenes; Peptide Fragments; Phorbols; Phosphorylation; Platelet-Derived Growth Factor; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine	1985
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms. Cell, 1986, Mar-28, Volume: 44, Issue:6 Topics: Alanine; Cell Line; DNA; Epidermal Growth Factor; ErbB Receptors; Humans; Methionine; Mutation; Phosphorylation; Protein Conformation; Protein Kinase C; Receptors, Cell Surface; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Threonine; Transcription, Genetic	1986
Effects of protein kinase C activation after epidermal growth factor binding on epidermal growth factor receptor phosphorylation. The Journal of biological chemistry, 1986, Aug-05, Volume: 261, Issue:22 Topics: Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Phosphorylation; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine; Tyrosine	1986
Epidermal growth factor (EGF) promotes phosphorylation at threonine-654 of the EGF receptor: possible role of protein kinase C in homologous regulation of the EGF receptor. The Journal of cell biology, 1986, Volume: 103, Issue:4 Topics: Carcinoma, Squamous Cell; Cell Line; Culture Media; Diglycerides; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Feedback; Humans; Hypertonic Solutions; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Threonine	1986
Release of a phorbol ester-induced mitogenic block by mutation at Thr-654 of the epidermal growth factor receptor. Molecular and cellular biology, 1988, Volume: 8, Issue:6 Topics: Animals; Base Sequence; Cell Line; Cloning, Molecular; Epidermal Growth Factor; ErbB Receptors; Mice; Mutation; Phosphorylation; Tetradecanoylphorbol Acetate; Threonine; Transfection	1988
Phorbol ester-induced threonine phosphorylation of the human epidermal growth factor receptor occurs within the EGF binding domain. Biochemical and biophysical research communications, 1984, Sep-17, Volume: 123, Issue:2 Topics: Binding Sites; Cell Line; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; Humans; Models, Biological; Neoplasms; Peptide Fragments; Phorbols; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine; Trypsin	1984
A novel substrate for insulin-sensitive serine/threonine kinase in intact cells. Endocrinology, 1994, Volume: 135, Issue:4 Topics: Animals; Antibodies; Carcinoma, Squamous Cell; CHO Cells; Cricetinae; Cycloheximide; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Humans; Immunoblotting; Insulin; Liver Neoplasms, Experimental; Membrane Proteins; Molecular Weight; Peptide Mapping; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Rats; Receptor, Insulin; Threonine; Tumor Cells, Cultured	1994
Identification, assay, and purification of a Cdc2-activating threonine-161 protein kinase from human cells. Archives of biochemistry and biophysics, 1994, Volume: 314, Issue:1 Topics: Animals; Blood Platelets; CDC2 Protein Kinase; Chromatography, High Pressure Liquid; Enzyme Activation; Epidermal Growth Factor; Humans; Hydrogen-Ion Concentration; Immunosorbent Techniques; Kinetics; Phosphorylation; Protein Kinases; Recombinant Proteins; Threonine; Tumor Cells, Cultured; Wilms Tumor	1994
Peptide segment ligation strategy without use of protecting groups. Proceedings of the National Academy of Sciences of the United States of America, 1994, Jul-05, Volume: 91, Issue:14 Topics: Amino Acid Sequence; Cysteine; Disulfides; Epidermal Growth Factor; Esters; Indicators and Reagents; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Peptides; Proteins; Threonine	1994
c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK. Nature, 1994, Sep-08, Volume: 371, Issue:6493 Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA-Binding Proteins; Epidermal Growth Factor; Humans; Mitogen-Activated Protein Kinase 1; Phosphorylation; Proline-Directed Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transcription Factor Pit-1; Transcription Factors; Transcription, Genetic; Ultraviolet Rays	1994
Bombesin and epidermal growth factor stimulate the mitogen-activated protein kinase through different pathways in Swiss 3T3 cells. The Biochemical journal, 1993, Jan-01, Volume: 289 ( Pt 1) Topics: 3T3 Cells; Animals; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Mice; Phosphorylation; Protein Kinase C; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine	1993
Direct evidence for tyrosine and threonine phosphorylation and activation of mitogen-activated protein kinase by vasopressin in cultured rat vascular smooth muscle cells. The Journal of biological chemistry, 1993, May-05, Volume: 268, Issue:13 Topics: 3T3 Cells; Amino Acid Sequence; Animals; Arginine Vasopressin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Culture Media, Serum-Free; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Kinetics; Mice; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Ribosomal Protein S6 Kinases; Threonine; Tyrosine; Virulence Factors, Bordetella	1993
Role of threonine residues in regulation of the epidermal growth factor receptor by protein kinase C and mitogen-activated protein kinase. The Journal of biological chemistry, 1993, Jul-25, Volume: 268, Issue:21 Topics: Animals; CHO Cells; Cloning, Molecular; Cricetinae; Epidermal Growth Factor; ErbB Receptors; Mitogen-Activated Protein Kinase 1; Mutation; Peptide Mapping; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Threonine; Transfection	1993
Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation. The Journal of biological chemistry, 1996, Apr-26, Volume: 271, Issue:17 Topics: 3T3 Cells; Actin Cytoskeleton; Actins; Amino Acid Sequence; Animals; Bacterial Toxins; Calcium-Calmodulin-Dependent Protein Kinases; Clostridium; Epidermal Growth Factor; Glucose; Glucosyltransferases; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; HeLa Cells; Humans; Kinetics; Mice; Molecular Sequence Data; Proto-Oncogene Proteins p21(ras); rac GTP-Binding Proteins; rap GTP-Binding Proteins; Threonine; Uridine Diphosphate Glucose	1996
HER-2/c-erbB2 is phosphorylated by calmodulin-dependent protein kinase II on a single site in the cytoplasmic tail at threonine-1172. Oncogene, 1996, Jun-20, Volume: 12, Issue:12 Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cytoplasm; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Humans; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Proto-Oncogene Mas; Rats; Receptor, ErbB-2; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Threonine	1996
Tyrosine phosphorylation of GSalpha and inhibition of bradykinin-induced activation of the cyclic AMP pathway in A431 cells by epidermal growth factor receptor. The Journal of biological chemistry, 1996, Dec-06, Volume: 271, Issue:49 Topics: Adenylyl Cyclases; Bradykinin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Humans; Isoproterenol; Oncogene Proteins; Phosphorylation; Serine; Threonine; Tumor Cells, Cultured; Tyrosine	1996
Detection of ERK activation by a novel monoclonal antibody. FEBS letters, 1997, May-26, Volume: 408, Issue:3 Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; COS Cells; Drosophila melanogaster; Enzyme Activation; Epidermal Growth Factor; Eukaryota; HeLa Cells; Humans; Kinetics; Mice; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphorylation; Point Mutation; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Signal Transduction; Spodoptera; Threonine; Transfection; Tyrosine	1997
Prolactin inhibits EGF-induced DNA synthesis in mammary epithelium via early signaling mechanisms: possible involvement of protein kinase C. Experimental cell research, 1997, Oct-10, Volume: 236, Issue:1 Topics: Animals; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Indoles; Iodine Radioisotopes; Maleimides; Mammary Glands, Animal; Mice; Naphthalenes; Phosphorylation; Prolactin; Protein Kinase C; Sensitivity and Specificity; Signal Transduction; Threonine	1997
Actin polymerization is required for negative feedback regulation of epidermal growth factor-induced signal transduction. Experimental cell research, 1998, Sep-15, Volume: 243, Issue:2 Topics: Actins; Biopolymers; Catalysis; Cytochalasin B; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation; Humans; Oncogenes; Phosphorylation; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Signal Transduction; Threonine; Tumor Cells, Cultured	1998
Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins. The Journal of cell biology, 1999, Jun-28, Volume: 145, Issue:7 Topics: Actin Cytoskeleton; Actins; Animals; Antigens, CD; Blood Proteins; Cadherins; Cell Adhesion Molecules; Cell Line; Cytoskeletal Proteins; Epidermal Growth Factor; Epithelial Cells; Fibroblasts; Humans; Hyaluronan Receptors; Leukosialin; Membrane Proteins; Microfilament Proteins; Microvilli; Phosphoproteins; Phosphorylation; Protein Binding; Recombinant Fusion Proteins; Sequence Deletion; Sialoglycoproteins; Threonine; Transfection	1999
Cell-type specific phosphorylation of threonines T654 and T669 by PKD defines the signal capacity of the EGF receptor. The EMBO journal, 1999, Oct-15, Volume: 18, Issue:20 Topics: 3T3 Cells; Animals; Cell Line; DNA; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Genes, fos; Genes, jun; Humans; Mice; Mutagenesis, Site-Directed; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins c-jun; Rats; Receptor Cross-Talk; RNA, Messenger; Signal Transduction; Threonine	1999
Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin. Cancer research, 1999, Oct-15, Volume: 59, Issue:20 Topics: Cell Adhesion; Cells, Cultured; Cortactin; Epidermal Growth Factor; Flavonoids; Humans; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Microfilament Proteins; Neoplasm Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; src Homology Domains; Structure-Activity Relationship; Threonine	1999
Detection of partially phosphorylated forms of ERK by monoclonal antibodies reveals spatial regulation of ERK activity by phosphatases. FEBS letters, 2000, Feb-18, Volume: 468, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites; Blotting, Western; Cell Nucleus; CHO Cells; Cricetinae; Cytoplasm; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Intracellular Fluid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Phosphoric Monoester Hydrolases; Phosphorylation; Signal Transduction; Threonine; Transfection; Tyrosine	2000
Characterization of hPRP4 kinase activation: potential role in signaling. Biochemical and biophysical research communications, 2000, May-10, Volume: 271, Issue:2 Topics: Animals; Blotting, Northern; Colforsin; COS Cells; DNA-Binding Proteins; Enzyme Activation; Epidermal Growth Factor; ets-Domain Protein Elk-1; Gene Library; Humans; Luciferases; Mutagenesis, Site-Directed; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Ribonucleoprotein, U4-U6 Small Nuclear; Signal Transduction; Threonine; Tissue Distribution; Transcription Factors; Transfection	2000
Control sites of ribosomal S6 kinase B and persistent activation through tumor necrosis factor. The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31 Topics: Amino Acid Sequence; Catalytic Domain; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; HeLa Cells; Humans; Indoles; Insulin; Ionomycin; Isoquinolines; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Substrate Specificity; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha	2000
Inhibition of Akt and its anti-apoptotic activities by tumor necrosis factor-induced protein kinase C-related kinase 2 (PRK2) cleavage. The Journal of biological chemistry, 2000, Nov-03, Volume: 275, Issue:44 Topics: Animals; Apoptosis; Caspases; Cell Line; Epidermal Growth Factor; Humans; Hydrolysis; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Threonine; Tumor Necrosis Factor-alpha; Two-Hybrid System Techniques	2000
Kinase suppressor of Ras signals through Thr269 of c-Raf-1. The Journal of biological chemistry, 2001, Mar-30, Volume: 276, Issue:13 Topics: Animals; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Humans; Mice; Mutation; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins c-raf; ras Proteins; Recombinant Proteins; Serine; Signal Transduction; Threonine; Transfection; Tyrosine; Valine	2001
Epidermal growth factor induction of apolipoprotein A-I is mediated by the Ras-MAP kinase cascade and Sp1. The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17 Topics: Amino Acid Sequence; Apolipoprotein A-I; Binding Sites; Blotting, Western; Chloramphenicol O-Acetyltransferase; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genes, Dominant; Genes, ras; Genes, Reporter; Humans; Insulin; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Kinase C; Protein Synthesis Inhibitors; Quinazolines; ras Proteins; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sp1 Transcription Factor; Threonine; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation	2001
Site-directed mutagenesis of heparin-binding EGF-like growth factor (HB-EGF): analysis of O-glycosylation sites and properties. Growth factors (Chur, Switzerland), 2001, Volume: 19, Issue:2 Topics: Alanine; Binding Sites; Blotting, Western; Chromatography, High Pressure Liquid; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Genetic Vectors; Glycosylation; HeLa Cells; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; Recombinant Proteins; Threonine; Vaccinia virus	2001
Epidermal growth factor stimulates serine/threonine phosphorylation of the focal adhesion protein paxillin in a MEK-dependent manner in normal rat kidney cells. Journal of cellular physiology, 2002, Volume: 191, Issue:1 Topics: Actins; Animals; Cell Adhesion; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Enzyme Activation; Epidermal Growth Factor; Kidney; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Paxillin; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Reference Values; Serine; Threonine	2002
Inhibitory effects of a luteinizing hormone-releasing hormone agonist on basal and epidermal growth factor-induced cell proliferation and metastasis-associated properties in human epidermoid carcinoma A431 cells. International journal of cancer, 2002, Jun-01, Volume: 99, Issue:4 Topics: Antineoplastic Agents, Hormonal; Carcinoma, Squamous Cell; Caspases; Cell Division; DNA Fragmentation; Enzyme Activation; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Humans; Immunoblotting; Matrix Metalloproteinases; Neoplasm Invasiveness; Phosphorylation; Precipitin Tests; Protein Tyrosine Phosphatases; Serine; Threonine; Time Factors; Triptorelin Pamoate; Tumor Cells, Cultured	2002
Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38. The EMBO journal, 2002, Jul-15, Volume: 21, Issue:14 Topics: Activating Transcription Factor 2; Blood; Cell Line; Cyclic AMP Response Element-Binding Protein; Epidermal Growth Factor; Humans; Insulin; MAP Kinase Signaling System; Phosphorylation; Threonine; Transcription Factors	2002
The interaction and phosphorylation of tropomodulin by protein kinase Calpha in N/N 1003A lens epithelial cells. Molecular vision, 2002, Oct-22, Volume: 8 Topics: Animals; Blotting, Western; Carrier Proteins; Cells, Cultured; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Isoenzymes; Lens, Crystalline; Microfilament Proteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Rabbits; Tetradecanoylphorbol Acetate; Threonine; Transfection; Tropomodulin	2002
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. Nature cell biology, 2003, Volume: 5, Issue:7 Topics: 3T3 Cells; Animals; Apoptosis; Base Sequence; Caspase 3; Caspase 9; Caspases; Cell Survival; Cell Transformation, Neoplastic; Cytochrome c Group; Enzyme Inhibitors; Epidermal Growth Factor; Eukaryotic Cells; HeLa Cells; Humans; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins; Signal Transduction; Threonine	2003
Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3'-OH kinase-Akt pathway. The Journal of biological chemistry, 2004, Jan-09, Volume: 279, Issue:2 Topics: Antibiotics, Antineoplastic; Apoptosis; Biotin; Caspase 9; Caspases; Cell Line; Cell Line, Tumor; Cell Membrane; Chromones; DNA Fragmentation; Down-Regulation; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Hepatocyte Growth Factor; Humans; Immunoblotting; Inositol; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Recombinant Proteins; Serine; Signal Transduction; Threonine; Time Factors	2004
p41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate. EMBO reports, 2004, Volume: 5, Issue:2 Topics: Actin Cytoskeleton; Actin-Related Protein 2-3 Complex; Actins; Cell Movement; Epidermal Growth Factor; Gene Library; Glutathione Transferase; Humans; Immunoprecipitation; Mutation; p21-Activated Kinases; Phalloidine; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein Subunits; RNA, Small Interfering; Threonine; Wound Healing	2004
Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation. The Journal of biological chemistry, 2005, Jul-01, Volume: 280, Issue:26 Topics: Amino Acid Sequence; Animals; Biotin; Blood Platelets; Blotting, Western; Cell Communication; Cell Line; Cloning, Molecular; COS Cells; Cross-Linking Reagents; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Epidermal Growth Factor; Eptifibatide; Flow Cytometry; Humans; Immunoprecipitation; Mass Spectrometry; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Peptides; Peroxidase; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Tissue Distribution; Transfection; Tyrosine	2005
Nuclear localization and mitogen-activated protein kinase phosphorylation of the multifunctional protein CAD. The Journal of biological chemistry, 2005, Jul-08, Volume: 280, Issue:27 Topics: Active Transport, Cell Nucleus; Animals; Aspartate Carbamoyltransferase; Breast Neoplasms; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Division; Cell Fractionation; Cell Line, Tumor; Cell Nucleus; Cricetinae; Cytoplasm; Dihydroorotase; Dihydroorotate Dehydrogenase; Epidermal Growth Factor; Fluorescent Antibody Technique; Humans; Kidney; Microscopy, Confocal; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Mutagenesis, Site-Directed; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Oxidoreductases Acting on CH-CH Group Donors; Phosphorylation; Pyrimidines; Threonine	2005
Structural bioinformatics-based design of selective, irreversible kinase inhibitors. Science (New York, N.Y.), 2005, May-27, Volume: 308, Issue:5726 Topics: Amino Acid Sequence; Animals; Binding Sites; Computational Biology; COS Cells; Cysteine; Cytidine Deaminase; Enzyme Inhibitors; Epidermal Growth Factor; Heterocyclic Compounds, 2-Ring; Histones; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Mutation; Phosphorylation; Protein Structure, Tertiary; Ribosomal Protein S6 Kinases, 90-kDa; Sequence Alignment; Serine; Structure-Activity Relationship; Threonine	2005
Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II. The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43 Topics: Atherosclerosis; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catalysis; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Epidermal Growth Factor; ErbB Receptors; Humans; Inflammation; Models, Biological; Mutation; Nitric Oxide; Nitric Oxide Synthase Type III; Peptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Receptor, PAR-1; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; src-Family Kinases; Threonine; Thrombin; Thrombomodulin; Time Factors; Tyrosine; Umbilical Veins	2005
Regulation of p90RSK phosphorylation by SARS-CoV infection in Vero E6 cells. FEBS letters, 2006, Feb-20, Volume: 580, Issue:5 Topics: Animals; Chlorocebus aethiops; Epidermal Growth Factor; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Signal Transduction; Threonine; Vero Cells	2006
Regulation of protein phosphatase 2A-mediated recruitment of IQGAP1 to beta1 integrin by EGF through activation of Ca2+/calmodulin-dependent protein kinase II. Journal of cellular physiology, 2006, Volume: 208, Issue:1 Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Female; Flow Cytometry; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Integrin beta1; Mammary Glands, Human; Phosphoprotein Phosphatases; Phosphorylation; Protein Interaction Mapping; Protein Phosphatase 2; rac GTP-Binding Proteins; ras GTPase-Activating Proteins; Threonine	2006
Sphingosine kinase type 2 activation by ERK-mediated phosphorylation. The Journal of biological chemistry, 2007, Apr-20, Volume: 282, Issue:16 Topics: Amino Acid Sequence; Cell Line, Tumor; Enzyme Activation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Humans; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Sequence Homology, Amino Acid; Threonine	2007
The threonine that carries fucose, but not fucose, is required for Cripto to facilitate Nodal signaling. The Journal of biological chemistry, 2007, Jul-13, Volume: 282, Issue:28 Topics: Amino Acid Substitution; Animals; Cell Differentiation; Cell Line; Embryonic Stem Cells; Epidermal Growth Factor; Fucose; Fucosyltransferases; GPI-Linked Proteins; Humans; Intercellular Signaling Peptides and Proteins; Membrane Glycoproteins; Mice; Mutation, Missense; Myocytes, Cardiac; Neoplasm Proteins; Nodal Protein; Protein Modification, Translational; Receptor, Notch1; Signal Transduction; Threonine; Transforming Growth Factor beta	2007
CDK2 regulation through PI3K and CDK4 is necessary for cell cycle progression of primary rat hepatocytes. Cell proliferation, 2007, Volume: 40, Issue:4 Topics: Active Transport, Cell Nucleus; Animals; Cell Cycle; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Epidermal Growth Factor; Hepatocytes; Male; Phosphatidylinositol 3-Kinases; Rats; Rats, Wistar; Threonine	2007
TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling. Molecular and cellular biology, 2009, Volume: 29, Issue:20 Topics: Anthracenes; Butadienes; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; HeLa Cells; Humans; Imidazoles; Lactones; MAP Kinase Kinase Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinazolines; Resorcinols; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha	2009
Kinase suppressor of Ras transphosphorylates c-Raf-1. Biochemical and biophysical research communications, 2009, Dec-18, Volume: 390, Issue:3 Topics: Animals; Antibodies, Monoclonal; Antibodies, Phospho-Specific; Chlorocebus aethiops; COS Cells; Epidermal Growth Factor; Humans; Mice; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-raf; Threonine	2009
P21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformation. Carcinogenesis, 2011, Volume: 32, Issue:5 Topics: Animals; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermal Growth Factor; Epidermis; Humans; Immunoenzyme Techniques; Immunoprecipitation; Melanoma; Mice; Mutation; p21-Activated Kinases; Phosphorylation; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Skin; Skin Neoplasms; Threonine; Tissue Array Analysis; Transcription Factor AP-1	2011
Growth hormone modulation of EGF-induced PI3K-Akt pathway in mice liver. Cellular signalling, 2012, Volume: 24, Issue:2 Topics: Adaptor Proteins, Signal Transducing; Animals; Epidermal Growth Factor; Gene Expression; Growth Hormone; Liver; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinase; Phosphoproteins; Phosphorylation; Protein Binding; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Serine; Signal Transduction; Threonine; TOR Serine-Threonine Kinases	2012
Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly. Molecular biology of the cell, 2012, Volume: 23, Issue:8 Topics: Animals; Cell Line; Cell Membrane; Cell Movement; Cell Proliferation; Chlorocebus aethiops; COS Cells; Epidermal Growth Factor; ErbB Receptors; Fluorescence Resonance Energy Transfer; HEK293 Cells; Hemidesmosomes; Humans; Integrin beta4; Keratinocytes; Mutation; Phosphorylation; Plectin; Protein Kinase C; Threonine	2012
Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Science signaling, 2015, Jun-09, Volume: 8, Issue:380 Topics: 14-3-3 Proteins; 3T3-L1 Cells; Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Enzyme Inhibitors; Epidermal Growth Factor; HEK293 Cells; Humans; Insulin; Mice; Phosphopeptides; Phosphoproteins; Phosphorylation; Proteomics; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Tandem Mass Spectrometry; Threonine; TOR Serine-Threonine Kinases	2015
Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation. Nature cell biology, 2015, Volume: 17, Issue:10 Topics: Acetylglucosamine; Animals; Cell Line; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Glioma; Humans; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Macrophage Migration-Inhibitory Factors; Matrix Metalloproteinase 13; Mice, Nude; Microscopy, Fluorescence; Mutation; Phosphorylation; Protein Binding; RNA Interference; Serine; Survival Analysis; Threonine; Transplantation, Heterologous	2015
PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736. PloS one, 2015, Volume: 10, Issue:11 Topics: Calcineurin; Calcium; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Transformed; Epidermal Growth Factor; Gene Expression Regulation; Hemidesmosomes; Humans; Integrin alpha6beta4; Kalinin; Keratinocytes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Plectin; Protein Kinase C-delta; Protein Structure, Tertiary; Pteridines; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; TRPP Cation Channels	2015
Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β. Molecular cell, 2016, 11-03, Volume: 64, Issue:3 Topics: Alternative Splicing; Animals; Cell Line, Tumor; DNA-Binding Proteins; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Exons; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Hyaluronan Receptors; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Neoplastic Stem Cells; Phosphorylation; Promoter Regions, Genetic; Protein Isoforms; RNA Precursors; RNA-Binding Proteins; Signal Transduction; Smad3 Protein; Threonine; Transforming Growth Factor beta	2016
The human transient receptor potential vanilloid 3 channel is sensitized via the ERK pathway. The Journal of biological chemistry, 2017, 12-22, Volume: 292, Issue:51 Topics: Boron Compounds; Cell Line, Transformed; Cymenes; Epidermal Growth Factor; ErbB Receptors; Green Fluorescent Proteins; HEK293 Cells; Humans; Keratinocytes; MAP Kinase Signaling System; Membrane Transport Modulators; Mitogen-Activated Protein Kinase 3; Monoterpenes; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Phosphorylation; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Recombinant Proteins; Threonine; TRPV Cation Channels; Up-Regulation	2017
Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells. PloS one, 2018, Volume: 13, Issue:2 Topics: Animals; Cell Line; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Hydrogen Peroxide; Lung; Male; Mice; Mitochondria; Mitogen-Activated Protein Kinase 1; Oxidation-Reduction; Phosphorylation; Subcellular Fractions; Threonine; Tyrosine	2018
EGF suppresses the expression of miR-124a in pancreatic β cell lines via ETS2 activation through the MEK and PI3K signaling pathways. International journal of biological sciences, 2019, Volume: 15, Issue:12 Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Diabetes Mellitus; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hepatocyte Nuclear Factor 3-beta; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Inbred C57BL; MicroRNAs; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Protein c-ets-2; Signal Transduction; Threonine	2019
δ-Catenin Participates in EGF/AKT/p21 International journal of molecular sciences, 2021, May-18, Volume: 22, Issue:10 Topics: Active Transport, Cell Nucleus; Binding Sites; Catenins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Delta Catenin; Epidermal Growth Factor; Humans; Ligands; Male; Models, Biological; Mutagenesis, Site-Directed; Neoplasm Invasiveness; PC-3 Cells; Phosphorylation; Prostatic Neoplasms; Protein Interaction Domains and Motifs; Protein Stability; Proto-Oncogene Proteins c-akt; Signal Transduction; Threonine	2021