threonine and calpain

threonine has been researched along with calpain in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's4 (20.00)18.2507
2000's10 (50.00)29.6817
2010's3 (15.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Christoph, G; Siman, R1
Blumenthal, EJ; Malkinson, AM; Miller, AC; Stein, GH1
Bartunik, HD; Bochtler, M; Ditzel, L; Groll, M; Huber, R; Löwe, J; Stock, D1
Aman, MJ; Henkart, PA; Leonard, WJ; Nakajima, H; Noguchi, M; Sarin, A; Shores, EW1
Baldin, V; Cans, C; Ducommun, B; Knibiehler, M1
de la Luz Ibarra, M; García, EJ; Jay, D; Lara, JE; Medina, MA1
Bordone, L; Campbell, C1
Alexa, A; Dombrádi, V; Friedrich, P; Kovács, J; Kulcsár, P; Ogueta, S; Schmidt, G; Tompa, P; Vázquez, J1
Agerholm-Larsen, B; Chen, W; Linsel-Nitschke, P; Martinez, LO; Silver, DL; Tall, AR; Wang, N1
Elce, JS; Huynh, KK; Jia, Z; Smith, SD; Wells, A1
Elce, JS; Hosfield, CM; Jia, Z1
Inanami, O; Kawahara, K; Kuwabara, M; Nakajima, T; Nomura, Y; Okuma, Y; Wakasa, T1
Chung, KC; Kim, HJ; Kim, J; Lee, CH; Lee, D; Paik, SR1
Baliova, M; Franekova, V; Jursky, F1
Minchin, RF; Mitchell, DJ1
Hu, JP; Teng, WP; Wang, CY; Wang, SL; Wang, T; Wang, X; Wang, ZY; Xie, JW1
Huang, Q; Lai, B; Li, M; Liu, S; Ma, S; Song, B; Wang, C; Xie, B1
Burster, T; Schauer, S; Spindler-Barth, M1
Abel, ED; Chen, B; Ciampa, G; Hall, DD; Peng, T; Shi, Q; Song, LS; Wang, J; Zheng, D1
Maitra, S; Vincent, B1

Reviews

1 review(s) available for threonine and calpain

ArticleYear
Cdk5-p25 as a key element linking amyloid and tau pathologies in Alzheimer's disease: Mechanisms and possible therapeutic interventions.
    Life sciences, 2022, Nov-01, Volume: 308

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Calpain; Cyclin-Dependent Kinase 5; Humans; Phosphorylation; Serine; tau Proteins; Threonine

2022

Other Studies

19 other study(ies) available for threonine and calpain

ArticleYear
beta-Amyloid precursor is a PEST protein.
    Biochemical and biophysical research communications, 1989, Dec-29, Volume: 165, Issue:3

    Topics: Amino Acid Sequence; Amyloid; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain Chemistry; Calpain; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Protease Inhibitors; Protein Precursors; Rats; Serine; Threonine

1989
Serine/threonine protein kinases and calcium-dependent protease in senescent IMR-90 fibroblasts.
    Mechanisms of ageing and development, 1993, Volume: 72, Issue:1

    Topics: Calcium; Calpain; Cell Line; Cellular Senescence; Diploidy; Endopeptidases; Fibroblasts; Humans; Osmolar Concentration; Protein Kinase C; Protein Kinases; Serine; Threonine

1993
Structure of 20S proteasome from yeast at 2.4 A resolution.
    Nature, 1997, Apr-03, Volume: 386, Issue:6624

    Topics: Acetylcysteine; Calpain; Crystallography, X-Ray; Cysteine Endopeptidases; Endopeptidases; Enzyme Inhibitors; Enzyme Precursors; Glycoproteins; Histocompatibility Antigens Class I; Models, Molecular; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Conformation; Saccharomyces cerevisiae; Thermoplasma; Threonine

1997
Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Oct-14, Volume: 94, Issue:21

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Calpain; CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Primers; Glutamic Acid; Humans; Interleukin-2; Ionomycin; Lymphocyte Activation; Macromolecular Substances; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Cytokine; Recombinant Proteins; Sequence Alignment; Serine; Signal Transduction; Substrate Specificity; T-Lymphocytes; Threonine

1997
Phosphorylation of human CDC25B phosphatase by CDK1-cyclin A triggers its proteasome-dependent degradation.
    The Journal of biological chemistry, 1997, Dec-26, Volume: 272, Issue:52

    Topics: Calpain; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cyclin A; Cysteine Endopeptidases; HeLa Cells; Humans; Leupeptins; Multienzyme Complexes; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Threonine; Tyrosine

1997
Determination of a cAMP-dependent protein kinase phosphorylation site in the C-terminal region of human endothelial actin-binding protein.
    Archives of biochemistry and biophysics, 2000, May-01, Volume: 377, Issue:1

    Topics: Amino Acid Motifs; Amino Acid Substitution; Blood Platelets; Calpain; Contractile Proteins; Cyclic AMP-Dependent Protein Kinases; Endothelium; Filamins; Humans; Immune Sera; Microfilament Proteins; Molecular Weight; Mutation; Peptide Fragments; Phosphorylation; Phosphoserine; Recombinant Proteins; Sequence Analysis, Protein; Serine; Threonine

2000
DNA ligase III is degraded by calpain during cell death induced by DNA-damaging agents.
    The Journal of biological chemistry, 2002, Jul-19, Volume: 277, Issue:29

    Topics: Amino Acid Motifs; Amino Acid Substitution; Apoptosis; Aspartic Acid; Calpain; DNA Damage; DNA Ligase ATP; DNA Ligases; Humans; Mutagenesis, Site-Directed; Poly-ADP-Ribose Binding Proteins; Proline; Recombinant Proteins; Serine; Threonine; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques; Xenopus Proteins

2002
The phosphorylation state of threonine-220, a uniquely phosphatase-sensitive protein kinase A site in microtubule-associated protein MAP2c, regulates microtubule binding and stability.
    Biochemistry, 2002, Oct-15, Volume: 41, Issue:41

    Topics: Amino Acid Sequence; Animals; Calpain; Cattle; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; Endopeptidases; Microtubule-Associated Proteins; Microtubules; Molecular Sequence Data; Phosphoprotein Phosphatases; Phosphorylation; Protein Binding; Rats; Swine; Threonine

2002
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.
    The Journal of clinical investigation, 2003, Volume: 111, Issue:1

    Topics: Amino Acid Sequence; Animals; Apolipoprotein A-I; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Calpain; Cell Line; Cell Membrane; Cells, Cultured; Chickens; Cholesterol; Cross-Linking Reagents; Dipeptides; DNA; Dose-Response Relationship, Drug; Endopeptidases; Glutamic Acid; Hepatocytes; Humans; Ligands; Lipid Metabolism; Macrophages; Mice; Molecular Sequence Data; Phospholipids; Plasmids; Proline; Serine; Threonine; Time Factors; Transfection; Up-Regulation

2003
Glutamate substitutions at a PKA consensus site are consistent with inactivation of calpain by phosphorylation.
    FEBS letters, 2003, May-08, Volume: 542, Issue:1-3

    Topics: Amino Acid Substitution; Animals; Calcium; Calpain; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; Enzyme Stability; Glutamic Acid; Mutation; Phosphorylation; Rats; Serine; Threonine

2003
Activation of calpain by Ca2+: roles of the large subunit N-terminal and domain III-IV linker peptides.
    Journal of molecular biology, 2004, Oct-29, Volume: 343, Issue:4

    Topics: Calcium; Calpain; Lysine; Mutation; Protein Structure, Tertiary; Threonine

2004
Dual inhibition of protein phosphatase-1/2A and calpain rescues nerve growth factor-differentiated PC12 cells from oxygen-glucose deprivation-induced cell death.
    Journal of neuroscience research, 2006, Feb-15, Volume: 83, Issue:3

    Topics: Animals; Blotting, Western; Calpain; Cell Differentiation; CREB-Binding Protein; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glucose; Hypoxia; L-Lactate Dehydrogenase; Nerve Growth Factor; Neural Inhibition; Neurons; Oncogene Protein v-akt; Oxygen; PC12 Cells; Phosphoprotein Phosphatases; Protein Phosphatase 1; Rats; Serine; Spectrin; tau Proteins; Threonine; Time Factors

2006
Calpain-resistant fragment(s) of alpha-synuclein regulates the synuclein-cleaving activity of 20S proteasome.
    Archives of biochemistry and biophysics, 2006, Nov-01, Volume: 455, Issue:1

    Topics: alpha-Synuclein; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Calpain; Electrophoresis, Polyacrylamide Gel; Glutamates; Hydrolysis; Models, Biological; Molecular Sequence Data; Mutation; Proline; Proteasome Endopeptidase Complex; Serine; Substrate Specificity; Swine; Threonine

2006
Truncation of human dopamine transporter by protease calpain.
    Neurochemistry international, 2008, Volume: 52, Issue:8

    Topics: Amino Acid Sequence; Animals; Calpain; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Female; Humans; Peptide Fragments; Protein Kinase C; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors for Activated C Kinase; Receptors, Cell Surface; Receptors, Dopamine D2; Recombinant Proteins; Serine; Synaptosomes; Threonine

2008
Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.
    Molecular pharmacology, 2009, Volume: 76, Issue:2

    Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Calpain; Cysteine Proteinase Inhibitors; Cytosol; Escherichia coli; Escherichia coli Proteins; Glutathione Transferase; Half-Life; HeLa Cells; Humans; Leupeptins; Molecular Sequence Data; NIMA-Interacting Peptidylprolyl Isomerase; Okadaic Acid; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Recombinant Proteins; Serine; Sulfotransferases; Threonine; Transfection; Two-Hybrid System Techniques

2009
Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways.
    Brain research bulletin, 2011, May-30, Volume: 85, Issue:3-4

    Topics: Amyloid beta-Protein Precursor; Animals; Brain; Calpain; Cell Line, Tumor; Cyclin-Dependent Kinase 5; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Mice; Mice, Transgenic; Neuroblastoma; Phosphorylation; Presenilin-1; Signal Transduction; tau Proteins; Threonine; Valproic Acid

2011
Site-specific phosphorylation protects glycogen synthase kinase-3β from calpain-mediated truncation of its N and C termini.
    The Journal of biological chemistry, 2012, Jun-29, Volume: 287, Issue:27

    Topics: Animals; Apoptosis; Calpain; Cerebellum; Glutamine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Isoleucine; Mutagenesis; Nerve Degeneration; Neurons; Phosphorylation; Protein Structure, Tertiary; Rabbits; Rats; Serine; Threonine

2012
N- and C-terminal degradation of ecdysteroid receptor isoforms, when transiently expressed in mammalian CHO cells, is regulated by the proteasome and cysteine and threonine proteases.
    Insect molecular biology, 2012, Volume: 21, Issue:3

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Calpain; Cathepsins; CHO Cells; Cricetinae; Cysteine Proteases; Drosophila melanogaster; Drosophila Proteins; Leupeptins; Mammals; Molecular Sequence Data; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Isoforms; Protein Multimerization; Protein Stability; Protein Structure, Tertiary; Proteolysis; Receptors, Steroid; Threonine; Transcription, Genetic; Ubiquitination

2012
Calpain-2 specifically cleaves Junctophilin-2 at the same site as Calpain-1 but with less efficacy.
    The Biochemical journal, 2021, 10-15, Volume: 478, Issue:19

    Topics: Animals; Arginine; Calpain; Disease Models, Animal; Glycine; Heart Failure; HEK293 Cells; Humans; Male; Membrane Proteins; Mice; Muscle Proteins; Mutagenesis, Site-Directed; Myocytes, Cardiac; Proteolysis; Signal Transduction; Threonine; Transfection

2021