threonine and bortezomib

threonine has been researched along with bortezomib in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (25.00)29.6817
2010's12 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biggs, JR; Garcia, M; Kraft, AS; Peterson, LF; Zhang, DE; Zhang, Y1
Morris, AP; Sellin, JH; Umar, S; Wang, Y1
Ludwig, A; Meiners, S; Stangl, K; Stangl, V1
Allievi, C; Berkers, C; Bernareggi, A; Bussolati, B; Camussi, G; Cassin, M; Coscia, M; Costa, G; de Feudis, P; di Giovine, S; Ferracini, R; Ferrero, D; Giai, V; Hunter, K; Inghirami, G; Jones-Bolin, S; Massaia, M; Neri, A; Nicoli, P; Ovaa, H; Palumbo, A; Peola, S; Pescalli, N; Pezzoni, G; Piva, R; Roato, I; Ruggeri, B; Strepponi, I; Tamagno, I; Williams, M; Zhao, H1
Berenson, JR; Bonavida, B; Chen, H; Li, M; Li, ZW; Sanchez, E; Shen, J; Steinberg, JA; Wang, C1
Kay, LE; Ruschak, AM; Schimmer, AD; Slassi, M1
Appel, A1
Gallastegui, N; Groll, M1
Hu, Y; Wu, P; Zhang, J1
Hiepe, F; Radbruch, A1
Kłoczko, J; Ołdziej, AE; Romaniuk, W; Zińczuk, J1
Bourenkov, G; Chari, A; Henneberg, F; Mata, RA; Schneider, TR; Schrader, J; Stark, H; Tittmann, K1
Bocchia, M; Brambilla, CZ; Candi, V; Gozzetti, A; Papini, G; Sirianni, S1
Antoniadi, G; Eleftheriadis, T; Liakopoulos, V; Pissas, G; Stefanidis, I1
Hasinoff, BB; Patel, D1
Hawkins, CJ; Patatsos, K; Shekhar, TM1

Reviews

6 review(s) available for threonine and bortezomib

ArticleYear
Proteasome inhibitors: poisons and remedies.
    Medicinal research reviews, 2008, Volume: 28, Issue:2

    Topics: Binding Sites; Boronic Acids; Bortezomib; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Threonine

2008
Novel proteasome inhibitors to overcome bortezomib resistance.
    Journal of the National Cancer Institute, 2011, Jul-06, Volume: 103, Issue:13

    Topics: Allosteric Site; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Chloroquine; Clioquinol; Drug Resistance, Neoplasm; Humans; Hydroxyquinolines; Lactones; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Threonine; Ubiquitinated Proteins; Ubiquitination

2011
Clinical and marketed proteasome inhibitors for cancer treatment.
    Current medicinal chemistry, 2013, Volume: 20, Issue:20

    Topics: Boron Compounds; Boronic Acids; Bortezomib; Glycine; Humans; Lactones; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Structure-Activity Relationship; Threonine

2013
Plasma cells as an innovative target in autoimmune disease with renal manifestations.
    Nature reviews. Nephrology, 2016, Volume: 12, Issue:4

    Topics: Autoantibodies; Autoimmune Diseases; B-Lymphocytes; Boronic Acids; Bortezomib; Glomerulonephritis; Humans; Immunologic Memory; Immunosuppressive Agents; Kidney Diseases; Lupus Nephritis; Oligopeptides; Peptides; Plasma Cells; Proteasome Inhibitors; Threonine

2016
[Proteasome inhibitors in cancer therapy].
    Postepy higieny i medycyny doswiadczalnej (Online), 2015, Dec-31, Volume: 69

    Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caspases; Dipeptides; Humans; Lactones; Multiple Myeloma; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Pyrroles; Thiazoles; Threonine

2015
Second Generation Proteasome Inhibitors in Multiple Myeloma.
    Anti-cancer agents in medicinal chemistry, 2017, Volume: 17, Issue:7

    Topics: Animals; Boronic Acids; Bortezomib; Central Nervous System Neoplasms; Drug Discovery; Humans; Lactones; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Proteasome Inhibitors; Pyrroles; Threonine

2017

Other Studies

10 other study(ies) available for threonine and bortezomib

ArticleYear
Phosphorylation of AML1/RUNX1 regulates its degradation and nuclear matrix association.
    Molecular cancer research : MCR, 2005, Volume: 3, Issue:7

    Topics: Animals; Boronic Acids; Bortezomib; Core Binding Factor Alpha 2 Subunit; DNA-Binding Proteins; Immunoprecipitation; Mice; Mice, Knockout; Mutation; Nuclear Matrix; Phosphorylation; Protease Inhibitors; Proto-Oncogene Proteins; Pyrazines; Serine; Threonine; Transcription Factors; Transcription, Genetic; Ubiquitin

2005
Dual alterations in casein kinase I-epsilon and GSK-3beta modulate beta-catenin stability in hyperproliferating colonic epithelia.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:2

    Topics: Animals; Axin Protein; beta Catenin; Boronic Acids; Bortezomib; Casein Kinase 1 epsilon; Cell Nucleus; Citrobacter rodentium; Colon; Cyclic AMP Response Element-Binding Protein; Cytoskeleton; DNA; Enterobacteriaceae Infections; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperplasia; Immunoprecipitation; Intestinal Mucosa; Mice; Phosphorylation; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Kinase C; Pyrazines; Repressor Proteins; Serine; TCF Transcription Factors; Threonine; Transcription Factor 7-Like 2 Protein

2007
CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib.
    Blood, 2008, Mar-01, Volume: 111, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Inhibitors; Humans; Macrophage Colony-Stimulating Factor; Mice; Mice, Nude; Multiple Myeloma; Neoplasms; NF-kappa B; Osteogenesis; Proteasome Inhibitors; Pyrazines; RANK Ligand; Threonine; Treatment Outcome; Ubiquitin; Xenograft Model Antitumor Assays

2008
The proteasome inhibitor CEP-18770 enhances the anti-myeloma activity of bortezomib and melphalan.
    British journal of haematology, 2010, Volume: 148, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Death; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Male; Melphalan; Mice; Mice, SCID; Multiple Myeloma; Proteasome Inhibitors; Pyrazines; Threonine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
Drugs: More shots on target.
    Nature, 2011, Dec-14, Volume: 480, Issue:7377

    Topics: Antineoplastic Agents; Boron Compounds; Boronic Acids; Bortezomib; Clinical Trials as Topic; Drug Resistance, Neoplasm; Glycine; Humans; Immunologic Factors; Lenalidomide; Multiple Myeloma; Oligopeptides; Protease Inhibitors; Pyrazines; Survival Rate; Thalidomide; Threonine

2011
Analysing properties of proteasome inhibitors using kinetic and X-ray crystallographic studies.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 832

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Lactones; Multiple Myeloma; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Saccharomyces cerevisiae; Threonine

2012
The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
    Science (New York, N.Y.), 2016, Aug-05, Volume: 353, Issue:6299

    Topics: Antineoplastic Agents; Biocatalysis; Boron Compounds; Boronic Acids; Bortezomib; Catalytic Domain; Crystallography, X-Ray; Drug Design; Glycine; Humans; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Conformation; Threonine

2016
A comparative analysis between proteasome and immunoproteasome inhibition in cellular and humoral alloimmunity.
    International immunopharmacology, 2017, Volume: 50

    Topics: Antibody-Dependent Cell Cytotoxicity; Boronic Acids; Bortezomib; Cell Proliferation; Cells, Cultured; Graft Rejection; Histocompatibility; Humans; Immunity, Cellular; Immunity, Humoral; Immunosuppression Therapy; Isoantibodies; Kidney Transplantation; Leukocytes, Mononuclear; Lymphocyte Culture Test, Mixed; Oligopeptides; Proteasome Inhibitors; Threonine

2017
Myocyte-Damaging Effects and Binding Kinetics of Boronic Acid and Epoxyketone Proteasomal-Targeted Drugs.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:6

    Topics: Animals; Animals, Newborn; Boron Compounds; Boronic Acids; Bortezomib; Cardiotoxicity; Cell Survival; Dose-Response Relationship, Drug; Epoxy Compounds; Glycine; Humans; K562 Cells; Ketones; Kinetics; Myocytes, Cardiac; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Rats, Sprague-Dawley; Threonine

2018
Pre-clinical evaluation of proteasome inhibitors for canine and human osteosarcoma.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:4

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Bone Neoplasms; Boron Compounds; Boronic Acids; Bortezomib; Carboplatin; Cell Line, Tumor; Dog Diseases; Dogs; Doxorubicin; Glycine; Humans; Oligopeptides; Osteosarcoma; Proteasome Inhibitors; Sulfonamides; Threonine

2018