Compounds > threonine

threonine and amyloid beta-peptides

threonine has been researched along with amyloid beta-peptides in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akiyama, H; Ikeda, K; Kondo, H; McGeer, PL; Mori, H; Nishimura, T; Oda, T; Sahara, N1
Aleshkov, SB; Lavrentiadou, SN; Li, X; Zannis, VI1
Ihara, Y; Mitsumori, R; Morishima-Kawashima, M; Qi, Y; Sato, T1
Barbiero, VS; Chiarini, S; Gennarelli, M; Gesuete, R; Musazzi, L; Popoli, M; Racagni, G; Rydel, RE; Tardito, D1
Gandy, S; Iijima, K; Iijima-Ando, K; Itohara, S; Mathews, PM; Nakaya, T; Pedrini, S; Sano, Y; Suzuki, T; Takeda, S1
Courtoy, PJ; Feyt, C; Kienlen-Campard, P; Octave, JN; Pierrot, N; Tasiaux, B; Van Hees, J1
Green, KN; LaFerla, FM; Martinez-Coria, H; Schreiber, SS; Steffan, JS; Sun, X; Thompson, LM1
Moir, RD; Myre, MA; Tanzi, RE; Tesco, G; Wasco, W; Washicosky, K1
Hsieh, SH; Sankaranarayanan, S; Savage, MJ; Simon, AJ; Wu, G1
Bowers, MT; Liu, D; Roychaudhuri, R; Teplow, DB; Zheng, X1
Conicella, AE; Fawzi, NL1

Other Studies

11 other study(ies) available for threonine and amyloid beta-peptides

ArticleYear
Variable deposition of amyloid beta-protein (A beta) with the carboxy-terminus that ends at residue valine40 (A beta 40) in the cerebral cortex of patients with Alzheimer's disease: a double-labeling immunohistochemical study with antibodies specific for
    Neurochemical research, 1997, Volume: 22, Issue:12

    Topics: Aged; Aged, 80 and over; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Antibodies; Antibody Specificity; Cerebral Cortex; Female; Humans; Immunohistochemistry; Male; Neurofibrillary Tangles; Peptide Fragments; Staining and Labeling; Threonine; Valine

1997
Contribution of cysteine 158, the glycosylation site threonine 194, the amino- and carboxy-terminal domains of apolipoprotein E in the binding to amyloid peptide beta (1-40).
    Biochemistry, 1999, Jul-13, Volume: 38, Issue:28

    Topics: Amino Acid Substitution; Amyloid beta-Peptides; Animals; Apolipoproteins E; Arginine; Binding Sites; Carbohydrate Conformation; Cell Line; Cricetinae; Cysteine; Electrophoresis, Polyacrylamide Gel; Glycosylation; Humans; Kidney; Macromolecular Substances; Peptide Fragments; Point Mutation; Protein Isoforms; Threonine

1999
Distinct mechanisms by mutant presenilin 1 and 2 leading to increased intracellular levels of amyloid beta-protein 42 in Chinese hamster ovary cells.
    Biochemistry, 2003, Feb-04, Volume: 42, Issue:4

    Topics: Amino Acid Substitution; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Asparagine; Aspartic Acid; Aspartic Acid Endopeptidases; Carbamates; Cell Line; Cell-Free System; CHO Cells; Cricetinae; Culture Media; Dipeptides; Endopeptidases; Humans; Intracellular Fluid; Isoleucine; Membrane Proteins; Methionine; Mutagenesis, Site-Directed; Peptide Fragments; Presenilin-1; Presenilin-2; Serine Proteinase Inhibitors; Threonine; Transfection; Up-Regulation; Valine

2003
Long-term soluble Abeta1-40 activates CaM kinase II in organotypic hippocampal cultures.
    Neurobiology of aging, 2007, Volume: 28, Issue:9

    Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Hippocampus; Organ Culture Techniques; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Threonine; Time Factors; Up-Regulation

2007
Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP.
    PloS one, 2006, Dec-20, Volume: 1

    Topics: Alzheimer Disease; Amino Acid Sequence; Amino Acid Substitution; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Base Sequence; Brain; DNA Primers; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Recombinant Proteins; Threonine

2006
Phosphorylation of APP695 at Thr668 decreases gamma-cleavage and extracellular Abeta.
    Biochemical and biophysical research communications, 2007, Jun-15, Volume: 357, Issue:4

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Binding Sites; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Extracellular Fluid; Mutagenesis, Site-Directed; Neurons; Peptide Fragments; Phosphorylation; Protein Binding; Rats; Rats, Wistar; Structure-Activity Relationship; Threonine

2007
Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Nov-05, Volume: 28, Issue:45

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Butyrates; Cell Line, Transformed; Cognition Disorders; Disease Models, Animal; Enzyme Inhibitors; Humans; Immunoprecipitation; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Mutation; Niacinamide; Peptide Fragments; Phosphorylation; Presenilin-1; Sirtuins; tau Proteins; Threonine; Time Factors; Transfection; Tubulin; Vitamin B Complex

2008
Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1.
    Cellular signalling, 2009, Volume: 21, Issue:4

    Topics: Acetylcysteine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzazepines; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclin D1; Fibroblasts; Glioma; Hexanones; Humans; Hydrocarbons, Chlorinated; Indoles; Leupeptins; Mice; Peptide Fragments; Proteasome Inhibitors; Purines; Recombinant Fusion Proteins; Roscovitine; Threonine

2009
Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
    Journal of neuroscience research, 2011, Volume: 89, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cerebral Cortex; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Peptide Fragments; Phosphorylation; tau Proteins; Threonine

2011
Amyloid β-Protein Assembly: Differential Effects of the Protective A2T Mutation and Recessive A2V Familial Alzheimer's Disease Mutation.
    ACS chemical neuroscience, 2015, Oct-21, Volume: 6, Issue:10

    Topics: Alanine; Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Humans; Hydrophobic and Hydrophilic Interactions; Mass Spectrometry; Microscopy, Electron, Transmission; Mutation; Peptide Fragments; Protein Structure, Secondary; Threonine; Valine

2015
The C-terminal threonine of Aβ43 nucleates toxic aggregation via structural and dynamical changes in monomers and protofibrils.
    Biochemistry, 2014, May-20, Volume: 53, Issue:19

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Humans; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Structure, Secondary; Threonine

2014