threonine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

threonine has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (14.29)18.2507
2000's17 (60.71)29.6817
2010's6 (21.43)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Alessi, DR; Andjelković, M; Cohen, P; Cron, P; Fernandez, A; Frech, M; Hemmings, BA; Lamb, NJ; Lucocq, JM; Meier, R1
Abraham, RT; Aebersold, R; Gingras, AC; Gygi, SP; Hoekstra, MF; Polakiewicz, RD; Raught, B; Sonenberg, N1
Bandyopadhyay, G; Burke, TR; Farese, RV; Quon, MJ; Sajan, MP; Standaert, ML1
Hara, K; Parekh, D; Parker, PJ; Yonezawa, K; Ziegler, W1
Arrieumerlou, C; Burgering, BM; Genot, EM; Kramer, IM; Ku, G; Weiss, A1
Forsthoefel, D; Hartman, M; Hofmeister, JK; Hume, DA; Ostrowski, MC; Schaffner, AE; Smith, JL; Wei, G1
Badorff, C; Dimmeler, S; Holzmann, Y; Rössig, L; Zeiher, AM1
Aschenbach, WG; Goodyear, LJ; Hirshman, MF; Sakamoto, K1
Hori, M; Kitagawa, K; Kuwabara, K; Mabuchi, T; Matsumoto, M; Omura-Matsuoka, E; Sasaki, T; Sugiura, S; Takasawa, K; Tanaka, S1
Ito, F; Takeuchi, K1
Ishikawa, K; Tokumoto, T; Watanabe, K1
Demetris, AJ; Han, C; Leng, J; Wu, T1
Dabiri, D; Esfandiarei, M; Luo, H; McManus, BM; Suarez, A; Yanagawa, B; Zhang, J1
Bernd, A; Guschel, M; Kaufmann, R; Kippenberger, S; Knies, Y; Loitsch, S; Müller, J1
Beugnet, A; Murakami, M; Proud, CG; Wang, X; Yamanaka, S1
Baran, V; Kalous, J; Kubelka, M; Motlik, J; Schultz, RM; Solc, P1
Misra, UK; Pizzo, SV1
Badger, TM; He, L; Mehendale, HM; Ronis, MJ; Simmen, FA1
Davis, S; Dufour, F; Horwood, JM; Laroche, S1
Cao, J; Chen, W; Dai, B; Lin, D; Liu, L; Liu, Y; Ma, D; Sun, Y; Yu, H1
Albert, L; Gulati, N; Jhanwar-Uniyal, M; Karsy, M; Murali, R1
Cheng, C; Cui, X; Gao, S; He, S; Ke, Q; Li, P; Liu, Y; Lu, M; Shen, A; Wang, Y; Xue, W; Zhao, Y1
Kay, EP; Lee, JG; Smith, RE; Song, JS1
Cinar, B; Collak, FK; Erkaya, B; Luthringer, DJ; Yagiz, K1
Doucette, CD; Hilchie, AL; Hoskin, DW; Liwski, R1
Branson, OE; Chaney, SB; Cheney, CM; Freitas, MA; Harshman, SW; Hoover, ME; Huang, C; Huebner, K; Rosol, TJ; Shapiro, CL; Wysocki, VH1
Dyckhoff, G; Freier, K; Freudlsperger, C; Grabe, N; Hess, J; Hoffmann, J; Horn, D; Plinkert, P; Saure, D; Sharma, S; Weber, KJ; Weichert, W; Weißfuß, S1

Other Studies

28 other study(ies) available for threonine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
Role of translocation in the activation and function of protein kinase B.
    The Journal of biological chemistry, 1997, Dec-12, Volume: 272, Issue:50

    Topics: Amino Acid Substitution; Biological Transport; Cell Membrane; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Humans; Insulin-Like Growth Factor I; Morpholines; Phosphorylation; Protein Serine-Threonine Kinases; Protein Sorting Signals; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Threonine

1997
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism.
    Genes & development, 1999, Jun-01, Volume: 13, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Antigen-Antibody Complex; Binding Sites; Carrier Proteins; Cell Cycle Proteins; Cell Line; Chromones; Culture Media, Serum-Free; Eukaryotic Initiation Factor-4E; Humans; Immunophilins; Molecular Sequence Data; Morpholines; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Isoforms; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Threonine; TOR Serine-Threonine Kinases

1999
Protein kinase C-zeta and phosphoinositide-dependent protein kinase-1 are required for insulin-induced activation of ERK in rat adipocytes.
    The Journal of biological chemistry, 1999, Oct-22, Volume: 274, Issue:43

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adipocytes; Amino Acid Substitution; Androstadienes; Animals; Chromones; Enzyme Activation; Enzyme Inhibitors; Epididymis; Flavonoids; Genistein; Insulin; Kinetics; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Recombinant Proteins; Signal Transduction; src Homology Domains; Threonine; Wortmannin

1999
Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon.
    The Journal of biological chemistry, 1999, Dec-03, Volume: 274, Issue:49

    Topics: Allosteric Regulation; Amino Acids; Cell Line; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Isoenzymes; Leucine; Morpholines; Naphthalenes; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinases; Serine; Signal Transduction; Sirolimus; Threonine; TOR Serine-Threonine Kinases; Transfection

1999
The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase.
    Molecular and cellular biology, 2000, Volume: 20, Issue:15

    Topics: Chromones; Cytoskeleton; Enzyme Activation; Enzyme Inhibitors; Humans; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Receptors, Antigen, T-Cell; T-Lymphocytes; Threonine; Tumor Cells, Cultured

2000
ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice.
    Molecular and cellular biology, 2000, Volume: 20, Issue:21

    Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Northern; Blotting, Western; Cell Line; Cell Survival; Chromones; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Macrophage Colony-Stimulating Factor; Macrophages; Membrane Proteins; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinases; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Protein c-ets-2; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Repressor Proteins; Scavenger Receptors, Class B; Signal Transduction; Threonine; Time Factors; Trans-Activators; Transcription Factors; Transfection; Urokinase-Type Plasminogen Activator

2000
Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation.
    The Journal of biological chemistry, 2002, Mar-22, Volume: 277, Issue:12

    Topics: Adjuvants, Immunologic; Androstadienes; Animals; Blotting, Western; Bromodeoxyuridine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Chromones; COS Cells; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Immunoblotting; Lithium Chloride; Morpholines; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Time Factors; Transfection; Umbilical Veins; Wortmannin

2002
Contraction regulation of Akt in rat skeletal muscle.
    The Journal of biological chemistry, 2002, Apr-05, Volume: 277, Issue:14

    Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Insulin; Morpholines; Muscle Contraction; Muscle, Skeletal; Phosphorylation; Protein Binding; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine; Wortmannin

2002
Differential Akt phosphorylation at Ser473 and Thr308 in cultured neurons after exposure to glutamate in rats.
    Neuroscience letters, 2002, Nov-29, Volume: 333, Issue:3

    Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromones; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Glutamic Acid; Glycogen Synthase Kinase 3; In Vitro Techniques; Morpholines; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Threonine; Time Factors

2002
Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3'-OH kinase-Akt pathway.
    The Journal of biological chemistry, 2004, Jan-09, Volume: 279, Issue:2

    Topics: Antibiotics, Antineoplastic; Apoptosis; Biotin; Caspase 9; Caspases; Cell Line; Cell Line, Tumor; Cell Membrane; Chromones; DNA Fragmentation; Down-Regulation; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Hepatocyte Growth Factor; Humans; Immunoblotting; Inositol; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Recombinant Proteins; Serine; Signal Transduction; Threonine; Time Factors

2004
1,10-Phenanthroline phosphorylates (activates) MAP kinase in Xenopus oocytes.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: Animals; Blotting, Western; Butadienes; Cell-Free System; Chromones; Colforsin; Cycloheximide; Enzyme Inhibitors; Female; Flavonoids; Indoles; Kinetics; Maleimides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oocytes; Pentetic Acid; Phenanthrolines; Phosphorylation; Progesterone; Threonine; Tyrosine; Xenopus laevis; Zinc Sulfate

2003
The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase 9; Caspases; Celecoxib; Cell Death; Cell Line, Tumor; Cell Survival; Cholangiocarcinoma; Chromones; Cyclooxygenase 2; Cytochromes c; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Immunoassay; Immunohistochemistry; Isoenzymes; Membrane Proteins; Microscopy, Fluorescence; Morpholines; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Sulfonamides; Threonine; Time Factors

2004
Protein kinase B/Akt regulates coxsackievirus B3 replication through a mechanism which is not caspase dependent.
    Journal of virology, 2004, Volume: 78, Issue:8

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Binding Sites; Capsid Proteins; Caspases; Chromones; Cysteine Proteinase Inhibitors; Enterovirus B, Human; Enzyme Inhibitors; HeLa Cells; Humans; MAP Kinase Signaling System; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA, Viral; Serine; Threonine; Ultraviolet Rays; Virus Replication

2004
Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor.
    The Journal of biological chemistry, 2005, Jan-28, Volume: 280, Issue:4

    Topics: Androstadienes; Apoptosis; Caspase 3; Caspase 8; Caspases; Cell Line; Cell Membrane; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermis; Epithelial Cells; ErbB Receptors; Genes, Dominant; Humans; Immunoblotting; Microscopy, Confocal; Morpholines; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, Angiotensin, Type 1; Signal Transduction; Threonine; Time Factors; Tyrphostins; Wortmannin

2005
Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.
    Molecular and cellular biology, 2005, Volume: 25, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amino Acids; Animals; Carrier Proteins; Cell Cycle Proteins; Cell Line; Chromones; Cricetinae; Eukaryotic Initiation Factor-4E; Humans; Insulin; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Morpholines; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinases; Rats; Ribosomal Protein S6 Kinases; Sequence Alignment; Serine; Signal Transduction; Sirolimus; Threonine; TOR Serine-Threonine Kinases

2005
PKB/AKT is involved in resumption of meiosis in mouse oocytes.
    Biology of the cell, 2006, Volume: 98, Issue:2

    Topics: 4-Butyrolactone; Animals; CDC2 Protein Kinase; Centrosome; Chromones; Enzyme Activation; Female; In Vitro Techniques; Meiosis; Mice; Morpholines; Nuclear Envelope; Okadaic Acid; Oocytes; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Serine; Threonine

2006
Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation.
    The Journal of biological chemistry, 2005, Nov-18, Volume: 280, Issue:46

    Topics: Androstadienes; Animals; bcl-Associated Death Protein; Blotting, Western; Cell Count; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gene Silencing; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoprecipitation; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; rap1 GTP-Binding Proteins; RNA Interference; RNA, Double-Stranded; Serine; Signal Transduction; Sulfonamides; Threonine; Thymidine; Time Factors; Up-Regulation; Wortmannin; X-Linked Inhibitor of Apoptosis Protein

2005
Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation.
    The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16

    Topics: Alcohol Dehydrogenase; Animals; Binding Sites; Blotting, Northern; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Chromones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Immunoprecipitation; Insulin; Liver; Male; Models, Biological; Molecular Sequence Data; Morpholines; Phosphorylation; Plasmids; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Messenger; Signal Transduction; Threonine; Transcription, Genetic

2006
Signalling mechanisms mediated by the phosphoinositide 3-kinase/Akt cascade in synaptic plasticity and memory in the rat.
    The European journal of neuroscience, 2006, Volume: 23, Issue:12

    Topics: Animals; Behavior, Animal; Chromones; Dentate Gyrus; Electrophysiology; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Forkhead Transcription Factors; Long-Term Potentiation; Male; Maze Learning; Memory; Morpholines; Nerve Tissue Proteins; Neuronal Plasticity; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Threonine; TOR Serine-Threonine Kinases

2006
S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.
    Journal of cellular physiology, 2009, Volume: 219, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Antineoplastic Agents; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Chromones; Cyclin B; Enzyme Inhibitors; Humans; Megakaryocytes; Morpholines; Nocodazole; Phosphoproteins; Phosphorylation; Polyploidy; Protein Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Sirolimus; Tetradecanoylphorbol Acetate; Threonine; TOR Serine-Threonine Kinases; Wortmannin

2009
Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    International journal of oncology, 2009, Volume: 35, Issue:4

    Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Antibiotics, Antineoplastic; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromones; Enzyme Activation; Fibronectins; Glioblastoma; Humans; Morpholines; Multiprotein Complexes; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Protein Kinases; Proteins; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; Regulatory-Associated Protein of mTOR; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; Serine; Signal Transduction; Sirolimus; STAT3 Transcription Factor; Threonine; Time Factors; TOR Serine-Threonine Kinases

2009
Phosphorylated p27Kip1 on Thr157 is an important prognosis in human hepatocellular carcinoma in vivo and in vitro.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:1

    Topics: Adult; Aged; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Female; Humans; Immunoenzyme Techniques; In Vitro Techniques; Ki-67 Antigen; Liver Neoplasms; Male; Middle Aged; Morpholines; Mutant Proteins; Mutation; Phosphorylation; Prognosis; Threonine; Tumor Cells, Cultured

2011
Human corneal endothelial cells employ phosphorylation of p27(Kip1) at both Ser10 and Thr187 sites for FGF-2-mediated cell proliferation via PI 3-kinase.
    Investigative ophthalmology & visual science, 2011, Oct-17, Volume: 52, Issue:11

    Topics: Adolescent; Adult; Aged; Butadienes; Cell Proliferation; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Endothelium, Corneal; Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Microscopy, Confocal; Middle Aged; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; RNA, Small Interfering; Serine; Tetrazolium Salts; Thiazoles; Threonine; Tissue Donors; Transfection; Young Adult

2011
Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1.
    The Journal of biological chemistry, 2012, Jul-06, Volume: 287, Issue:28

    Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Chromones; HEK293 Cells; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Nude; Morpholines; Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; RNA Interference; Signal Transduction; Sirolimus; Threonine; TOR Serine-Threonine Kinases; Transplantation, Heterologous; Tumor Burden

2012
Piperine, a dietary phytochemical, inhibits angiogenesis.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:1

    Topics: Alkaloids; Angiogenesis Inhibitors; Animals; Aorta; Benzodioxoles; Breast Neoplasms; Cell Movement; Cell Proliferation; Chick Embryo; Chromones; Drug Screening Assays, Antitumor; Female; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Morpholines; Neovascularization, Pathologic; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-akt; Rats, Wistar; S Phase; Serine; Threonine; TRPV Cation Channels

2013
Histone H1 phosphorylation in breast cancer.
    Journal of proteome research, 2014, May-02, Volume: 13, Issue:5

    Topics: Amino Acid Sequence; Blotting, Western; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromatography, Liquid; Chromones; Enzyme Inhibitors; Estradiol; Female; Histones; Humans; Immunohistochemistry; Mass Spectrometry; MCF-7 Cells; Molecular Sequence Data; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Isoforms; Proteomics; Threonine

2014
Phosphorylation of AKT(Ser473) serves as an independent prognostic marker for radiosensitivity in advanced head and neck squamous cell carcinoma.
    International journal of cancer, 2015, Jun-15, Volume: 136, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Chromones; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Morpholines; Multivariate Analysis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Serine; Survival Analysis; Threonine; Tissue Culture Techniques

2015