thiourea has been researched along with trifluoromethanesulfonic-acid* in 1 studies
1 other study(ies) available for thiourea and trifluoromethanesulfonic-acid
| Article | Year |
|---|---|
2-Nitro-thioglycosides: α- and β-selective generation and their potential as β-selective glycosyl donors.
Michael-type addition of thiolates to 2-nitro-D-glucal or to 2-nitro-D-galactal derivatives readily provides 2-deoxy-2-nitro-1-thioglycosides. Kinetic and thermodynamic reaction control permitted formation of either the α- or preferentially the β-anomers, respectively. Addition of achiral and chiral thiourea derivatives to the reaction mixture increased the reaction rate; the outcome is substrate-controlled. The 2-deoxy-2-nitro-1-thioglycosides are excellent glycosyl donors under arylsulfenyl chloride/silver triflate (ArSCl/AgOTf) activation, and they provide, anchimerically assisted by the nitro group, mostly β-glycosides. Topics: Combinatorial Chemistry Techniques; Glycosylation; Kinetics; Mesylates; Molecular Structure; Nitro Compounds; Stereoisomerism; Thermodynamics; Thioglycosides; Thiourea | 2015 |