thiourea has been researched along with sesamol* in 2 studies
2 other study(ies) available for thiourea and sesamol
| Article | Year |
|---|---|
Organocatalytic asymmetric Friedel-Crafts reaction of sesamol with isatins: access to biologically relevant 3-aryl-3-hydroxy-2-oxindoles.
The Friedel-Crafts reaction of electron-rich phenols with isatins was developed by employing bifunctional thiourea-tertiary amine organocatalysts. Cinchona alkaloid derived thiourea epiCDT-3 a efficiently catalyzed the Friedel-Crafts-type addition of phenols to isatin derivatives to provide 3-aryl-3-hydroxy-2-oxindoles 7 and 9 in good yield (80-95 %) with good enantiomeric excess (83-94 %). Friedel-Crafts adduct 7 t was subjected to a copper(I)-catalyzed azide-alkyne cycloaddition to obtain biologically important 3-aryl-3-hydroxy-2-oxindole 11 in good enantiomeric excess and having a 1,2,3-triazole moiety. Topics: Benzodioxoles; Catalysis; Cinchona Alkaloids; Indoles; Isatin; Models, Molecular; Molecular Structure; Phenols; Thiourea | 2014 |
[Studies on chemical protectors against radiation. XXXIII. Protective mechanisms of various compounds against skin injury induced by radiation].
The radiation protective mechanisms on skin injury induced by soft X-irradiation were investigated by use of various radiation protective agents such as sulfur compounds (MEA, MEG, thiourea), nucleic acid constitutional compounds (adenosine, inosine), antioxidative compounds (sesamol, ferulic acid, ascorbic acid), crude drugs (Rosae Fructus, Anemarrhenae Rhizoma, Trapae Fructus, Forsythiae Fructus, Aloe arborescens). Scavenge action of activated oxygen, inhibitory effect of lipid peroxidation, induction of antioxidative protein and protective effect against damage of deoxyribonucleic acid and superoxide dismutase by X-irradiation were evaluated as the radiation protective mechanisms, and relationship between these results and protective effect of skin injury induced by radiation was studied. Topics: Adenosine; Animals; Benzodioxoles; Coumaric Acids; Drugs, Chinese Herbal; Free Radical Scavengers; Lipid Peroxidation; Male; Mice; Nucleic Acids; Phenols; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Skin; Thiourea; Thymidine | 1991 |