thiourea has been researched along with pyrrolidine* in 4 studies
1 review(s) available for thiourea and pyrrolidine
| Article | Year |
|---|---|
Organocatalytic asymmetric epoxidation and aziridination of olefins and their synthetic applications.
Topics: Alkenes; Amines; Aspartic Acid; Aziridines; Catalysis; Molecular Structure; Peptides; Pyrrolidines; Thiourea | 2014 |
3 other study(ies) available for thiourea and pyrrolidine
| Article | Year |
|---|---|
A chiral benzoylthiourea-pyrrolidine catalyst for the highly enantioselective Michael addition of ketones to chalcones.
A benzoylthiourea-pyrrolidine catalyst was developed for the asymmetric Michael addition of ketones to chalcones. The corresponding products were obtained in high yields with high level of diastereoselectivities (up to 99:1 dr) and high level of enantioselectivities (up to 94% ee) under mild conditions. Topics: Catalysis; Chalcones; Ketones; Molecular Conformation; Pyrrolidines; Stereoisomerism; Thiourea | 2014 |
Organocatalytic stereocontrolled synthesis of 3,3'-pyrrolidinyl spirooxindoles by [3+2] annulation of isocyanoesters with methyleneindolinones.
A stereoselective [3+2] cycloaddition of isocyanoesters to methyleneindolinones catalyzed by a quinine-based thiourea-tertiary amine has been successfully developed. Just by tuning the protecting groups on substrates, a variety of optically enriched 3,3'-pyrrolidinyl spirooxindole diastereomers could be obtained in excellent enantioselectivities (up to 99% ee). Topics: Amines; Catalysis; Crystallography, X-Ray; Cyclization; Indoles; Molecular Conformation; Pyrrolidines; Quinine; Stereoisomerism; Thiourea | 2012 |
Highly enantioselective synthesis of gamma-nitro heteroaromatic ketones in a doubly stereocontrolled manner catalyzed by bifunctional thiourea catalysts based on dehydroabietic amine: a doubly stereocontrolled approach to pyrrolidine carboxylic acids.
A new class of dehydroabietic amine-substituted primary amine-thiourea bifunctional catalysts were designed and synthesized. The doubly stereocontrolled organocatalytic conjugate addition of a variety of heterocycles-bearing ketones to nitroalkenes was investigated for the first time, affording (S)- or (R)-gamma-nitro heteroaromatic ketones with excellent enantioselectivities (up to ee >99%). Furthermore, the nearly optically pure gamma-nitro heteroaromatic ketones can be readily transformed into chiral pyrrolidine carboxylic acids. Topics: Abietanes; Amines; Carboxylic Acids; Catalysis; Ketones; Molecular Structure; Pyrrolidines; Stereoisomerism; Thiourea | 2009 |