thiourea has been researched along with propyleneimine* in 2 studies
2 other study(ies) available for thiourea and propyleneimine
| Article | Year |
|---|---|
Genotoxic evaluation of ten carcinogens in the Drosophila melanogaster wing spot test.
To provide further background data on the wing spot somatic mutation and recombination assay, 10 selected carcinogens (acetamide, acrylamide, benzo(a)pyrene, cyclophosphamide, diethylstilbestrol, 4-nitroquinoline N-oxide, propyleneimine, safrole, thiourea, and o-toluidine) were tested in this assay. 72-h-old third-instar larvae, trans-heterozygous for 2 recessive wing cell markers: multiple wing hairs (mwh) and flare3 (flr3) were fed with 3 concentrations of each carcinogen during the rest of their development until pupation, and the genotoxic effects were measured as significant increases in the appearance of visible mutant hair clones on the adult wing blade. Our results show that 6 of the carcinogens tested produce significant increases in wing spot frequency, at least at one of the concentrations assayed. Benzo(a)pyrene, diethylstilbestrol, safrole and thiourea were the compounds that did not increase the incidence of mutant clones. Topics: 4-Nitroquinoline-1-oxide; Acetamides; Acrylamide; Acrylamides; Animals; Aziridines; Benzo(a)pyrene; Biological Assay; Carcinogens; Cyclophosphamide; Diethylstilbestrol; Drosophila melanogaster; Mutagenicity Tests; Safrole; Thiourea; Toluidines; Wings, Animal | 1995 |
Genotoxicity studies with the unstable zeste-white (UZ) system of Drosophila melanogaster: results with ten carcinogenic compounds.
To increase the number of chemicals tested using the zeste-white (UZ) somatic mutation assay, ten selected carcinogens (acetamide, acrylamide, benzo(alpha)pyrene, cyclophosphamide, diethylstilbestrol, 4-nitroquinoline N-oxide, propyleneimine, safrole, thiourea, and o-toluidine) have been evaluated in this assay. Our results show that all the compounds tested produce significant increases in the eye spot frequency at, at least, one of the concentrations assayed, indicating that the zeste-white assay appears to be highly sensitive to these carcinogenic compounds. That is in agreement with data previously reported by other authors. Topics: 4-Nitroquinoline-1-oxide; Acetamides; Acrylamide; Acrylamides; Animals; Aziridines; Benzo(a)pyrene; Carcinogens; Cyclophosphamide; Diethylstilbestrol; Drosophila melanogaster; Mutagenicity Tests; Mutagens; Safrole; Thiourea; Toluidines | 1991 |