thiourea and oroidin

thiourea has been researched along with oroidin* in 1 studies

Other Studies

1 other study(ies) available for thiourea and oroidin

ArticleYear
Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    The synthesis and antibiofilm activities of sulfonamide, urea, and thiourea oroidin analogues are described. The most active derivative was able to selectively inhibit P. aeruginosa biofilm development and is also shown to be nontoxic upward of 1 mM to the development of C. elegans in comparison to other similar isosteric analogues and the natural product oroidin.

    Topics: Amides; Animals; Anti-Bacterial Agents; Biofilms; Caenorhabditis elegans; Pseudomonas aeruginosa; Pyrroles; Structure-Activity Relationship; Sulfonamides; Thiourea; Urea

2009