thiourea has been researched along with methyl-salicylate* in 2 studies
2 other study(ies) available for thiourea and methyl-salicylate
Article | Year |
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Bisthioureas of pimelic acid and 4-methylsalicylic acid derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP): Synthesis and molecular docking studies.
Alkaline phosphatases (ALPs) are membrane bound metalloenzymes, distributed all over the body. Recent studies have revealed that by targeting ALPs can lead towards the treatment of many deadliest diseases including cardiac, cancerous and brain diseases. Thioureas and their derivatives are of considerable significance and are privileged scaffolds in medicinal chemistry. They show a wide range of pharmacological activities such as antibacterial, antiparasitic, anti-inflammatory and antioxidants etc. On the other hand, salicylic acid and its derivatives are known for its broad spectrum of activities. The work presented comprises of synthesis of N-acyl-N'-aryl substituted bisthioureas of pimelic acid (1-7) and 3,5-dimethyl pyrazole (11), 1-aroyl-3-aryl thiourea (12) and 1,3,4-oxadiazole (13) derivatives of 4-methyl salicylic acid. Structures of all the synthesized compounds were characterized by FT-IR and Topics: Alkaline Phosphatase; Enzyme Inhibitors; Hydrogen Bonding; Intestines; Molecular Docking Simulation; Pimelic Acids; Salicylates; Structure-Activity Relationship; Thiourea | 2020 |
[Effects of dihydrogenated alkaloids of argot on the experimental pulmonary edema caused by adrenalin, methyl-salicylate and thiourea].
Topics: Alkaloids; Edema; Epinephrine; Pulmonary Edema; Salicylates; Thiourea | 1950 |