thiourea and fluorophosphate

thiourea has been researched along with fluorophosphate* in 1 studies

Other Studies

1 other study(ies) available for thiourea and fluorophosphate

Article	Year
In vitro DNA scission activity of heterometallocenes. Dalton transactions (Cambridge, England : 2003), 2007, Feb-21, Issue:7 A comparative DNA scission activity study of azaferrocene, N-methyl-azaferrocene iodide and 3,3',4,4'-tetramethyl-1,1'-diphosphaferrocene (featuring iron in a +2 oxidation state), along with ferrocene (iron +2) and ferrocenium (iron +3) cation is described. Experiments indicate a high cleavage activity of azaferrocene and its N-methyl derivative in DMSO. DNA cleavage activity can be slowed down by addition of a free radical scavenger (thiourea) or triggered by addition of a reductive agent (dithiothreitol, DTT). The X-ray crystal structure of the N-methyl-2,5-dimethylazaferrocene cation (iron +2) with hexafluorophosphate as counter anion is also reported. Topics: Aza Compounds; Crystallography, X-Ray; Dithiothreitol; DNA; DNA Cleavage; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Ferric Compounds; Ferrous Compounds; Fluorides; Free Radical Scavengers; Ions; Metallocenes; Organometallic Compounds; Phosphates; Reducing Agents; Thiourea	2007

Article

Year

In vitro DNA scission activity of heterometallocenes.

Dalton transactions (Cambridge, England : 2003), 2007, Feb-21, Issue:7

A comparative DNA scission activity study of azaferrocene, N-methyl-azaferrocene iodide and 3,3',4,4'-tetramethyl-1,1'-diphosphaferrocene (featuring iron in a +2 oxidation state), along with ferrocene (iron +2) and ferrocenium (iron +3) cation is described. Experiments indicate a high cleavage activity of azaferrocene and its N-methyl derivative in DMSO. DNA cleavage activity can be slowed down by addition of a free radical scavenger (thiourea) or triggered by addition of a reductive agent (dithiothreitol, DTT). The X-ray crystal structure of the N-methyl-2,5-dimethylazaferrocene cation (iron +2) with hexafluorophosphate as counter anion is also reported.

Topics: Aza Compounds; Crystallography, X-Ray; Dithiothreitol; DNA; DNA Cleavage; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Ferric Compounds; Ferrous Compounds; Fluorides; Free Radical Scavengers; Ions; Metallocenes; Organometallic Compounds; Phosphates; Reducing Agents; Thiourea

2007