thiourea and dynorphin-(1-8)

thiourea has been researched along with dynorphin-(1-8)* in 1 studies

Other Studies

1 other study(ies) available for thiourea and dynorphin-(1-8)

Article	Year
New tris-alkoxycarbonyl arginine derivatives for peptide synthesis. Journal of peptide science : an official publication of the European Peptide Society, 2005, Volume: 11, Issue:1 alpha-Alkoxycarbonyl protected ornithines were treated with N,N'-[Z(2Cl)](2)-S-methylisothiourea and N,N'-[Z(2Br)](2)-S-methylisothiourea, N,N'-Z(2)-S-methylisothiourea and N,N'-Boc(2)-S-methylisothiourea to form N(alpha, omega, omega')-tris-alkoxycarbonyl arginines. Two of them, Boc-Arg-{omega,omega'-[Z(2Br)](2)}-OH and Boc-Arg-{omega,omega'-[Z(2Cl)](2)}-OH, were used for the synthesis of dermorphin fragments containing two or three arginine residues. Examination of the products by HPLC and ESI-MS revealed that the purity of the materials obtained with the use of the new derivatives was higher than that obtained in concurrent syntheses in which Boc-Arg(Tos) was used. Topics: Arginine; Dynorphins; Methods; Peptide Fragments; Peptides; Thiourea	2005

Article

Year

New tris-alkoxycarbonyl arginine derivatives for peptide synthesis.

Journal of peptide science : an official publication of the European Peptide Society, 2005, Volume: 11, Issue:1

alpha-Alkoxycarbonyl protected ornithines were treated with N,N'-[Z(2Cl)](2)-S-methylisothiourea and N,N'-[Z(2Br)](2)-S-methylisothiourea, N,N'-Z(2)-S-methylisothiourea and N,N'-Boc(2)-S-methylisothiourea to form N(alpha, omega, omega')-tris-alkoxycarbonyl arginines. Two of them, Boc-Arg-{omega,omega'-[Z(2Br)](2)}-OH and Boc-Arg-{omega,omega'-[Z(2Cl)](2)}-OH, were used for the synthesis of dermorphin fragments containing two or three arginine residues. Examination of the products by HPLC and ESI-MS revealed that the purity of the materials obtained with the use of the new derivatives was higher than that obtained in concurrent syntheses in which Boc-Arg(Tos) was used.

Topics: Arginine; Dynorphins; Methods; Peptide Fragments; Peptides; Thiourea

2005