thiourea and chloroacetamide

thiourea has been researched along with chloroacetamide* in 1 studies

Other Studies

1 other study(ies) available for thiourea and chloroacetamide

Article	Year
Selective thiourea optical probe based on thiourea-induced removal of chloroacetyl group from chloroacetylamine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2006, Volume: 65, Issue:5 A novel chromogenic probe for thiourea, N-chloroacetyl parafuchsin (CAP), was designed and synthesized. The method was based on the reaction of CAP with thiourea, resulting in the initial formation of the S-substituted thioformamidine hydrochloride, which would then undergo the intramolecular amidinolysis to liberate the corresponding amine, and thus leading to an absorbance increase at visible spectral range. Based on this mechanism, a highly selective optical probe for thiourea was developed. Under optimal conditions, absorbance increase (DeltaA) at 562 nm is proportional to thiourea concentration up to 0.2 mmolL(-1) with a detection limit of 2.1 micromolL(-1) (3sigma). Because of the selective removal of chloroacetyl group from CAP by thiourea, there is little interference by other molecules. Topics: Acetamides; Chloroacetates; Color; Hydrogen-Ion Concentration; Models, Biological; Solvents; Spectrum Analysis; Temperature; Thiourea; Time Factors; Trichloroacetic Acid; Trityl Compounds	2006

Article

Year

Selective thiourea optical probe based on thiourea-induced removal of chloroacetyl group from chloroacetylamine.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2006, Volume: 65, Issue:5

A novel chromogenic probe for thiourea, N-chloroacetyl parafuchsin (CAP), was designed and synthesized. The method was based on the reaction of CAP with thiourea, resulting in the initial formation of the S-substituted thioformamidine hydrochloride, which would then undergo the intramolecular amidinolysis to liberate the corresponding amine, and thus leading to an absorbance increase at visible spectral range. Based on this mechanism, a highly selective optical probe for thiourea was developed. Under optimal conditions, absorbance increase (DeltaA) at 562 nm is proportional to thiourea concentration up to 0.2 mmolL(-1) with a detection limit of 2.1 micromolL(-1) (3sigma). Because of the selective removal of chloroacetyl group from CAP by thiourea, there is little interference by other molecules.

Topics: Acetamides; Chloroacetates; Color; Hydrogen-Ion Concentration; Models, Biological; Solvents; Spectrum Analysis; Temperature; Thiourea; Time Factors; Trichloroacetic Acid; Trityl Compounds

2006