thiourea and 3-4-dihydroxy-1-2-epoxy-1-2-3-4-tetrahydrobenz(a)anthracene

thiourea has been researched along with 3-4-dihydroxy-1-2-epoxy-1-2-3-4-tetrahydrobenz(a)anthracene* in 1 studies

Other Studies

1 other study(ies) available for thiourea and 3-4-dihydroxy-1-2-epoxy-1-2-3-4-tetrahydrobenz(a)anthracene

Article	Year
Direct labeling of DNA-adducts formed from carcinogenic diol-epoxides with a fluorescent reporter compound specific for the cis vic-diol group. Biochemical and biophysical research communications, 1991, Nov-14, Volume: 180, Issue:3 The fluorescent reporter group, N-(5-FLUORESCEINYL),N'-(3-BORONATOPHENYL)THIOUREA (FABA) has been synthesized. This boronate group makes the reporter specific for cis vic-diols. The reporter group is bound to DNA-adducts formed from the reaction of calf-thymus DNA and benzanthracene trans-10,11-dihydrodiol,8,9-epoxide (anti), benzo(a)anthracene-trans-3,4-dihydrodiol-1,2-epoxide (anti) but is not bound to 3-methylcholanthrene-11,12 dihydro-epoxide. Femtomole quantities of adduct may be detected. Topics: Benz(a)Anthracenes; Carcinogens; DNA; Fluoresceins; Fluorescent Dyes; Methylcholanthrene; Molecular Structure; Thiourea	1991

Article

Year

Direct labeling of DNA-adducts formed from carcinogenic diol-epoxides with a fluorescent reporter compound specific for the cis vic-diol group.

Biochemical and biophysical research communications, 1991, Nov-14, Volume: 180, Issue:3

The fluorescent reporter group, N-(5-FLUORESCEINYL),N'-(3-BORONATOPHENYL)THIOUREA (FABA) has been synthesized. This boronate group makes the reporter specific for cis vic-diols. The reporter group is bound to DNA-adducts formed from the reaction of calf-thymus DNA and benzanthracene trans-10,11-dihydrodiol,8,9-epoxide (anti), benzo(a)anthracene-trans-3,4-dihydrodiol-1,2-epoxide (anti) but is not bound to 3-methylcholanthrene-11,12 dihydro-epoxide. Femtomole quantities of adduct may be detected.

Topics: Benz(a)Anthracenes; Carcinogens; DNA; Fluoresceins; Fluorescent Dyes; Methylcholanthrene; Molecular Structure; Thiourea

1991