Page last updated: 2024-08-16

thiotepa and mesna

thiotepa has been researched along with mesna in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (50.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Beijnen, JH; Maes, RA; Rodenhuis, S; van Tellingen, O; van Warmerdam, LJ1
Cruz, JM; Fleming, RA; Hurd, DD; Kucera, GL; Perry, JJ; Webb, CD1
Champlin, R; Deisseroth, AB; Holmes, F; Hortobagyi, G1
Betts, E; Goebel, ME; Honegger, H; Jost, LM; Nagler, A; Stahel, RA1
Palangié, T; Pierga, JY; Pouillart, P1
Allen, J; Atlas, MP; Dunkel, IJ; Fangusaro, JR; Finlay, JL; Gardner, S; Gonzalez-Gomez, I; Jubran, RF; Miller, D; Rosenblum, M1
Beijnen, JH; Ekhart, C; Huitema, AD; Rodenhuis, S1

Reviews

1 review(s) available for thiotepa and mesna

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for thiotepa and mesna

ArticleYear
Validation of a limited sampling model for carboplatin in a high-dose chemotherapy combination.
    Cancer chemotherapy and pharmacology, 1994, Volume: 35, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cyclophosphamide; Drug Administration Schedule; Hematopoietic Stem Cell Transplantation; Humans; Infusions, Intravenous; Mesna; Models, Biological; Reproducibility of Results; Thiotepa

1994
Urinary elimination of cyclophosphamide alkylating metabolites and free thiols following two administration schedules of high-dose cyclophosphamide and mesna.
    Bone marrow transplantation, 1996, Volume: 17, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Carboplatin; Cyclophosphamide; Cystitis; Drug Administration Schedule; Female; Hemorrhage; Humans; Infusions, Intravenous; Male; Mesna; Middle Aged; Neoplasms; Sulfhydryl Compounds; Thiotepa; Urinary Bladder

1996
Randomized trial showing equivalent efficacy of filgrastim 5 micrograms/kg/d and 10 micrograms/kg/d following high-dose chemotherapy and autologous bone marrow transplantation in high-risk lymphomas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hodgkin Disease; Humans; Lymphoma, Non-Hodgkin; Male; Melphalan; Mesna; Middle Aged; Neutropenia; Patient Selection; Recombinant Proteins; Thiotepa

1997
Dose-intense salvage therapy after neoadjuvant chemotherapy: feasibility and preliminary results.
    Cancer chemotherapy and pharmacology, 1999, Volume: 44 Suppl

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Lymphatic Metastasis; Melphalan; Mesna; Middle Aged; Pilot Projects; Salvage Therapy; Tegafur; Thiotepa; Vinblastine; Vinorelbine

1999
Brainstem primitive neuroectodermal tumors (bstPNET): results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Damage, Chronic; Brain Stem; Carboplatin; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Etoposide; Humans; Infant; Infratentorial Neoplasms; Leucovorin; Mesna; Methotrexate; Neuroectodermal Tumors, Primitive; Peripheral Blood Stem Cell Transplantation; Remission Induction; Thiotepa; Transplantation, Autologous; Vincristine

2008

Other Studies

4 other study(ies) available for thiotepa and mesna

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Use of safety-modified retroviruses to introduce chemotherapy resistance sequences into normal hematopoietic cells for chemoprotection during the therapy of breast cancer: a pilot trial.
    Human gene therapy, 1996, Feb-10, Volume: 7, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Diseases; Breast Neoplasms; Carmustine; Cyclophosphamide; Defective Viruses; DNA, Complementary; DNA, Recombinant; Drug Resistance, Neoplasm; Ethics, Medical; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Interleukin-3; Interleukin-6; Mesna; Middle Aged; Paclitaxel; Pilot Projects; Recombinant Fusion Proteins; Retroviridae; Safety; Thiotepa

1996
Pharmacokinetics of cyclophosphamide and thiotepa in a conventional fractionated high-dose regimen compared with a novel simplified unfractionated regimen.
    Therapeutic drug monitoring, 2009, Volume: 31, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Breast Neoplasms; Chromatography, Gas; Chromatography, High Pressure Liquid; Cyclophosphamide; Expectorants; Female; Forecasting; Humans; Infusions, Intravenous; Male; Mesna; Models, Statistical; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Testicular Neoplasms; Thiotepa

2009
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