thiorphan has been researched along with retrothiorphan in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (66.67) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crippen, GM | 1 |
| Böhm, M; Klebe, G | 1 |
| Devi, LA; Fournié-Zaluski, MC; Gagnidze, K; Orng, SV; Ouimet, T; Poras, H; Roques, BP | 1 |
| Corvol, P; el Amrani, AI; Fournié-Zaluski, MC; Michel, JB; Pham, I; Roques, B | 1 |
| Beaumont, A; Ficheux, D; Fournié-Zaluski, MC; Lucas, E; Michel, JB; Roques, BP; Soleilhac, JM; Turcaud, S | 1 |
| Barbe, B; Beaumont, A; Boileau, G; Crine, P; Fournié-Zaluski, MC; Le Moual, H; Roques, BP | 1 |
| Fournié-Zaluski, MC; Lévy, B; Michel, JB; Pham, I; Poitevin, P; Roques, BP | 1 |
| Bernard, E; Hornebeck, W; Robert, L | 1 |
| el Amrani, AI; Fournié-Zaluski, MC; Gonzalez, W; Laboulandine, I; Michel, JB; Pham, I; Philippe, M; Roques, BP | 1 |
| Beslot, F; Claperon, N; Fournie-Zaluski, MC; Peyroux, J; Roques, BP | 1 |
| Doucet, J; Fournie-Zaluski, MC; Gonzalez, W; Michel, JB; Pham, I; Roques, BP | 1 |
| Auburtin, G; Lafuma, C; Porcher, JM; Roques, BP; Soleilhac, JM | 1 |
| Adam, A; Blais, C; Drapeau, G; Gervais, N; Lamontagne, D; Raymond, P; Venneman, I | 1 |
| Adam, A; Blais, C; Dumoulin, MJ; Lamontagne, D | 1 |
| Arbin, V; Claperon, N; Fournié-Zaluski, MC; Peyroux, J; Roques, BP | 1 |
| Houard, X; Jacob, MP; Meilhac, O; Michel, JB; Mtairag, el M; Oudghiri, M; Pasquier, C; Rais, S | 1 |
| Chant, R; Davies, J; Powell, R; Simpson, S | 1 |
| Benaglia, M; Forni, A; Pirola, M; Puglisi, A; Raimondi, L | 1 |
18 other study(ies) available for thiorphan and retrothiorphan
| Article | Year |
|---|---|
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data.
Topics: Algorithms; Animals; Binding Sites; Computer Simulation; Folic Acid Antagonists; Models, Molecular; Peptidyl-Dipeptidase A; Protein Binding; Receptors, Cell Surface; Sex Hormone-Binding Globulin; Steroids; Testosterone; Tetrahydrofolate Dehydrogenase; Transcortin | 1997 |
Development of new hydrogen-bond descriptors and their application to comparative molecular field analyses.
Topics: Databases, Factual; Hydrogen Bonding; Ligands; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Thermolysin | 2002 |
Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay.
Topics: Animals; Aspartic Acid Endopeptidases; Endothelin-Converting Enzymes; Endothelins; Enzyme Assays; Enzyme Inhibitors; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Humans; Metalloendopeptidases; Mice; Organ Specificity; Peptide Library; Peptides; Substrate Specificity | 2010 |
Effects of the selective neutral endopeptidase inhibitor, retrothiorphan, on renal function and blood pressure in conscious normotensive Wistar and hypertensive DOCA-salt rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Bradykinin; Cyclic GMP; Desoxycorticosterone; Diuresis; Hypertension; Kidney; Kininogens; Male; Natriuresis; Neprilysin; Rats; Rats, Wistar; Sulfhydryl Compounds; Thiorphan | 1992 |
A 94-kDa protein, identified as neutral endopeptidase-24.11, can inactivate atrial natriuretic peptide in the vascular endothelium.
Topics: Amino Acid Sequence; Animals; Atrial Natriuretic Factor; Autoradiography; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enkephalin, Leucine-2-Alanine; Humans; In Vitro Techniques; Molecular Sequence Data; Neprilysin; Rats; Sulfhydryl Compounds; Thiorphan | 1992 |
Charge polarity reversal inverses the specificity of neutral endopeptidase-24.11.
Topics: Binding Sites; Cell Line; DNA; Electrochemistry; Enkephalin, Leucine-2-Alanine; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Substrate Specificity; Sulfhydryl Compounds; Thiorphan | 1992 |
Acute hemodynamic effects of combined inhibition of neutral endopeptidase and angiotensin converting enzyme in spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Drug Therapy, Combination; Enalaprilat; Heart Rate; Hemodynamics; Hypertension; Kinetics; Neprilysin; Rats; Rats, Inbred SHR; Thiorphan; Time Factors | 1995 |
[Elastase-type endopeptidase of fibroblasts. Effect of metalloprotease inhibitors].
Topics: Adult; Female; Fibroblasts; Glycopeptides; Humans; Neprilysin; Pancreatic Elastase; Protease Inhibitors; Skin; Thiorphan | 1995 |
Effects of converting enzyme inhibitor and neutral endopeptidase inhibitor on blood pressure and renal function in experimental hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Desoxycorticosterone; Diuresis; Enalaprilat; Hypertension, Renovascular; Kidney; Male; Natriuresis; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred SHR; Rats, Wistar; Sodium Chloride; Sulfhydryl Compounds; Thiorphan | 1993 |
Effect of endopeptidase-24.11 inhibitors and C-ANP receptor ligand on responses evoked in arterioles of rat cremaster muscle by atrial natriuretic peptide.
Topics: Abdominal Muscles; Adenosine; Administration, Topical; Animals; Arterioles; Atrial Natriuretic Factor; Blood Pressure; Dipeptides; Injections, Intravenous; Male; Neprilysin; Nitroprusside; Peptide Fragments; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Thiorphan; Vasodilator Agents | 1995 |
Effects of angiotensin-converting enzyme and neutral endopeptidase inhibitors: influence of bradykinin.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Cyclic GMP; Enalaprilat; Hypertension; Kidney; Male; Neprilysin; Rats; Rats, Wistar; Thiorphan | 1996 |
Characterization of a soluble form of neutral endopeptidase-24.11 (EC 3.4.24.11) in human serum: enhancement of its activity in serum of underground miners exposed to coal dust particles.
Topics: Coal; Coal Mining; Dust; Humans; Immunoblotting; Neprilysin; Pneumoconiosis; Protease Inhibitors; Solubility; Thiorphan | 1996 |
Contribution of angiotensin-converting enzyme to the cardiac metabolism of bradykinin: an interspecies study.
Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies; Bradykinin; Cross Reactions; Dogs; Enalaprilat; Humans; Kinetics; Losartan; Myocardium; Peptidyl-Dipeptidase A; Protease Inhibitors; Rabbits; Rats; Species Specificity; Substrate Specificity; Thiorphan | 1997 |
Metabolism of bradykinin by the rat coronary vascular bed.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Chromatography, High Pressure Liquid; Coronary Circulation; Coronary Vessels; Enalaprilat; Hemodynamics; Immunoenzyme Techniques; In Vitro Techniques; Male; Neprilysin; Perfusion; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Thiorphan; Time Factors | 1998 |
Effects of combined neutral endopeptidase 24-11 and angiotensin-converting enzyme inhibition on femoral vascular conductance in streptozotocin-induced diabetic rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Femoral Artery; Hemodynamics; Kininogens; Lysine Carboxypeptidase; Male; Neprilysin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Thiorphan; Time Factors | 2000 |
Pharmacological potentiation of natriuretic peptide limits polymorphonuclear neutrophil-vascular cell interactions.
Topics: Atrial Natriuretic Factor; Cell Adhesion; Cell Communication; Cell Degranulation; Culture Media, Conditioned; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Fibronectins; Humans; Hypoxia; Leukocyte Elastase; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Neprilysin; Neutrophil Activation; Neutrophils; Respiratory Burst; Thiorphan; Umbilical Veins | 2002 |
Routine antenatal anti-D prophylaxis--is the protection adequate?
Topics: Delivery, Obstetric; Female; Fetus; Humans; Infant, Newborn; Isoantibodies; Male; Pregnancy; Premedication; Prenatal Care; Rh Isoimmunization; Rho(D) Immune Globulin; Thiorphan | 2011 |
Evaluation of In-Batch and In-Flow Synthetic Strategies towards the Stereoselective Synthesis of a Fluorinated Analogue of Retro-Thiorphan.
Topics: Catalysis; Halogenation; Models, Molecular; Molecular Structure; Oxidation-Reduction; Stereoisomerism; Thiorphan | 2019 |