thiorphan has been researched along with neurokinin a in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (25.93) | 18.7374 |
| 1990's | 18 (66.67) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Drazen, JM; Martins, MA; Shore, SA | 2 |
| Bel, EH; Cheung, D; Den Hartigh, J; Dijkman, JH; Sterk, PJ | 1 |
| Buckner, CK; DeHaas, CJ; Krell, RD; Kusner, EJ; Lengel, DJ; Marks, RL | 1 |
| Drazen, JM; Gerard, C; Gerard, NP; Martins, MA; Shore, SA | 1 |
| Dolara, P; Maggi, CA; Morbidelli, L; Pacini, M; Ziche, M | 1 |
| Kondo, M; Takizawa, T; Tamaoki, J | 1 |
| Geppetti, P; Grassi, J; Maillet, S; Mantellini, P; Renzi, D; Santicioli, P; Surrenti, C; Theodorsson, E | 1 |
| Barnes, J; Frossard, N | 1 |
| Basbaum, CB; Borson, DB; Graf, PD; Nadel, JA; Sekizawa, K; Tamaoki, J | 1 |
| Advenier, C; Devillier, P; Drapeau, G; Marsac, J; Regoli, D | 1 |
| Drapeau, G; Maggi, CA; Meli, A; Patacchini, R; Regoli, D; Renzi, D; Rovero, P; Santicioli, P; Surrenti, C | 1 |
| Maggi, CA; Meli, A; Patacchini, R; Rovero, P | 1 |
| Webber, SE | 1 |
| Cherniack, NS; Deal, EC; Haxhiu, MA; van Lunteren, E | 1 |
| Drazen, JM; Shore, SA | 1 |
| Joos, GF; Kips, JC; Pauwels, RA | 1 |
| Bertrand, C; Da Silva, A; Landry, Y | 1 |
| Kurihara, T; Otsuka, M; Yoshioka, K | 1 |
| Hosoki, R; Otsuka, M; Saito, K; Seno, N; Suzuki, H; Yanagisawa, M | 1 |
| Bryce, DK; Desai, MC; Heym, J; Longo, KP; McLean, S; Rosen, T; Schmidt, AW; Snider, RM | 1 |
| Cheung, D; den Hartigh, J; Dijkman, JH; Sterk, PJ; Timmers, MC; Zwinderman, AH | 1 |
| Costa, C; Cozzolino, A; Esposito, C; Falciani, M; Filippelli, A; Porta, R; Rossi, F | 1 |
| Anthes, J; Chapman, RW; Egan, RW; Greenfeder, S; Hey, JA; Kreutner, W; Mauser, PJ; Rasquinha, C; Sherwood, JE | 1 |
| Exintaris, B; Lang, RJ | 1 |
| Coupar, IM; Kerr, KP; Thai, B | 1 |
| Dournaud, P; Fontaine, RH; Gressens, P; Lebas, F; Lelièvre, V; Leroux, P; Medja, F; Ouimet, T; Rougeot, C; Saria, A | 1 |
1 trial(s) available for thiorphan and neurokinin a
| Article | Year |
|---|---|
The effect of an inhaled neutral endopeptidase inhibitor, thiorphan, on airway responses to neurokinin A in normal humans in vivo.
Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Humans; Male; Methacholine Chloride; Neprilysin; Neurokinin A; Premedication; Thiorphan; Time Factors | 1992 |
26 other study(ies) available for thiorphan and neurokinin a
| Article | Year |
|---|---|
Effect of the NEP inhibitor SCH32615 on airway responses to intravenous substance P in guinea pigs.
Topics: Airway Resistance; Animals; Blood Pressure; Captopril; Dipeptides; Guinea Pigs; Injections, Intravenous; Male; Neprilysin; Neurokinin A; Substance P; Thiorphan | 1992 |
Tachykinin-induced dyspnea in conscious guinea pigs.
Topics: Aerosols; Animals; Drug Interactions; Dyspnea; Guinea Pigs; Male; Neurokinin A; SRS-A; Substance P; Thiorphan | 1992 |
Peptidase modulation of the pulmonary effects of tachykinins in tracheal superfused guinea pig lungs.
Topics: Animals; Captopril; Dipeptides; Guinea Pigs; Kinetics; Lung; Male; Neurokinin A; Peptide Hydrolases; Perfusion; Substance P; Thiorphan; Trachea | 1990 |
NK1-receptors mediate the proliferative response of human fibroblasts to tachykinins.
Topics: Autoradiography; Cell Division; Fibroblasts; Humans; In Vitro Techniques; Neurokinin A; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Skin; Substance P; Tachykinins; Thiorphan; Thymidine | 1990 |
Neutral endopeptidase inhibitor potentiates the tachykinin-induced increase in ciliary beat frequency in rabbit trachea.
Topics: Animals; Male; Mucociliary Clearance; Neprilysin; Neurokinin A; Rabbits; Stimulation, Chemical; Substance P; Thiorphan; Trachea | 1990 |
Enzyme immunoassay for tachykinin-like immunoreactivity in the guinea pig spinal cord.
Topics: Acetylcholinesterase; Animals; Capsaicin; Eledoisin; Guinea Pigs; Immunoenzyme Techniques; Kassinin; Male; Neurokinin A; Neurokinin B; Physalaemin; Potassium; Radioimmunoassay; Spinal Cord; Substance P; Tachykinins; Thiorphan | 1991 |
Effect of tachykinins in small human airways.
Topics: Bronchi; Bronchoconstriction; Carbachol; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Substance P; Thiorphan | 1991 |
Peptidase modulation of the pulmonary effects of tachykinins.
Topics: Animals; Captopril; Dipeptides; Guinea Pigs; In Vitro Techniques; Lung; Neprilysin; Neurokinin A; Perfusion; Substance P; Thiorphan | 1991 |
Enkephalinase inhibitor potentiates mammalian tachykinin-induced contraction in ferret trachea.
Topics: Animals; Atropine; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epithelium; Ferrets; In Vitro Techniques; Metalloendopeptidases; Muscle Contraction; Neprilysin; Neurokinin A; Neurokinin B; Neuropeptides; Substance P; Tachykinins; Thiorphan; Tiopronin; Trachea | 1987 |
Comparison of the effects of epithelium removal and of an enkephalinase inhibitor on the neurokinin-induced contractions of guinea-pig isolated trachea.
Topics: Airway Resistance; Animals; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Neprilysin; Neurokinin A; Neurokinin B; Substance P; Tachykinins; Thiorphan; Trachea | 1988 |
Effect of thiorphan on response of the guinea-pig gallbladder to tachykinins.
Topics: Animals; Captopril; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Substance P; Tachykinins; Thiorphan | 1989 |
The hamster isolated trachea: a new preparation for studying NK-2 receptors.
Topics: Animals; Atropine; Cricetinae; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Pyrilamine; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tachykinins; Thiorphan; Trachea | 1989 |
Receptors mediating the effects of substance P and neurokinin A on mucus secretion and smooth muscle tone of the ferret trachea: potentiation by an enkephalinase inhibitor.
Topics: Animals; Female; Ferrets; In Vitro Techniques; Male; Mucus; Muramidase; Muscle Tonus; Muscle, Smooth; Neprilysin; Neurokinin A; Receptors, Cell Surface; Serum Albumin, Bovine; Substance P; Thiorphan; Trachea | 1989 |
Central modulatory effects of tachykinin peptides on airway tone.
Topics: Airway Resistance; Animals; Cats; Female; Glycopeptides; Male; Medulla Oblongata; Neprilysin; Neurokinin A; Phrenic Nerve; Substance P; Thiorphan; Trachea | 1989 |
Degradative enzymes modulate airway responses to intravenous neurokinins A and B.
Topics: Animals; Bronchi; Captopril; Guinea Pigs; Infusions, Intravenous; Male; Neprilysin; Neurokinin A; Neurokinin B; Thiorphan; Trachea | 1989 |
In vivo characterization of the tachykinin receptors involved in the direct and indirect bronchoconstrictor effect of tachykinins in two inbred rat strains.
Topics: Airway Resistance; Animals; Atropine; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Captopril; Dose-Response Relationship, Drug; Indoles; Isoindoles; Male; Methysergide; Neurokinin A; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Tachykinin; Serotonin; Substance P; Thiorphan | 1994 |
Epithelium modulates the kinetics of the response to substance P and its intrinsic activity in the guinea-pig trachea.
Topics: Animals; Carbachol; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Substance P; Thiorphan; Trachea | 1994 |
Tachykininergic slow depolarization of motoneurones evoked by descending fibres in the neonatal rat spinal cord.
Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ketanserin; Motor Neurons; Neurokinin A; Rats; Rats, Wistar; Spinal Nerve Roots; Substance P; Synaptic Transmission; Tachykinins; Thiorphan; Thyrotropin-Releasing Hormone | 1995 |
Potentiating effect of peptidase inhibitors on a C fiber-evoked response in the isolated spinal cord preparation of the neonatal rat.
Topics: Animals; Animals, Newborn; Captopril; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Guanidines; Hydroxamic Acids; In Vitro Techniques; Kinetics; Leucine; Nerve Fibers; Neurokinin A; Protease Inhibitors; Rats; Rats, Wistar; Spinal Cord; Spinal Nerve Roots; Substance P; Tetrodotoxin; Thiorphan | 1993 |
CP-99,994, a nonpeptide antagonist of the tachykinin NK1 receptor.
Topics: Albuterol; Animals; Binding, Competitive; Calcium Channels; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Kinetics; Lung; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Thiorphan; Verapamil | 1993 |
Neutral endopeptidase activity and airway hyperresponsiveness to neurokinin A in asthmatic subjects in vivo.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Double-Blind Method; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Neprilysin; Neurokinin A; Thiorphan | 1993 |
Transglutaminase-synthesized spermine derivative of substance P recognizes rat portal vein neurokinin-3 receptors.
Topics: Androstanes; Animals; Benzimidazoles; In Vitro Techniques; Male; Neurokinin A; Peptide Fragments; Physalaemin; Piperidines; Portal Vein; Rats; Rats, Wistar; Receptors, Neurokinin-3; Substance P; Thiorphan; Transglutaminases; Vasoconstriction | 1997 |
Sch 37224, an experimental antiallergy compound, inhibits the neuropeptide component of hyperventilation- and nicotine-induced bronchoconstriction in guinea pigs.
Topics: Animals; Bronchoconstriction; Bronchoconstrictor Agents; Glycopeptides; Guinea Pigs; Histamine H1 Antagonists; Hyperventilation; Male; Metalloendopeptidases; Naphthyridines; Neurokinin A; Nicotine; Protease Inhibitors; Thiorphan | 1997 |
Effects of nerve stimulation on spontaneously active preparations of the guinea pig ureter.
Topics: Action Potentials; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Electrophysiology; Guinea Pigs; Humans; In Vitro Techniques; Motor Activity; Nervous System Physiological Phenomena; Neurokinin A; Peptides, Cyclic; Substance P; Tachykinins; Thiorphan; Ureter; Urinary Tract Physiological Phenomena | 1999 |
Tachykinin-induced contraction of the guinea-pig isolated oesophageal mucosa is mediated by NK(2) receptors.
Topics: Animals; Benzamides; Captopril; Dose-Response Relationship, Drug; Esophagus; Guinea Pigs; In Vitro Techniques; Mucous Membrane; Muscle Contraction; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Protease Inhibitors; Quinolines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Tachykinins; Thiorphan | 2000 |
Thiorphan, a neutral endopeptidase inhibitor used for diarrhoea, is neuroprotective in newborn mice.
Topics: Animals; Animals, Newborn; Caspase 3; Cell Death; Cells, Cultured; Cerebral Cortex; Cerebral Palsy; Excitatory Amino Acid Agonists; Female; Ibotenic Acid; Immunohistochemistry; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Neprilysin; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Protease Inhibitors; Receptors, Neurokinin-2; Seizures; Substance P; Thiorphan | 2006 |