thiorphan and morphine

thiorphan has been researched along with morphine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199013 (54.17)18.7374
1990's10 (41.67)18.2507
2000's1 (4.17)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bokszanska, A; Brinkman, EC; Cappendijk, SL; Dzoljic, M; Dzoljic, MR; Kaplan, CD; Korenhof, AM; Rupreht, J; Zijlstra, FJ1
Fournié-Zaluski, MC; Maldonado, R; Roques, BP1
Bousselmame, R; Costentin, J; Michael-Titus, A1
Berend, N; Breslin, AB; Kemsley, L; Panaretto, K; Peters, MJ1
Holroyde, MC; Jackson, DM; Leeson, ME; Norris, AA1
Suh, HH; Tseng, LL1
Conti, A; Marzanatti, M; Monopoli, A; Ongini, E; Trampus, M1
Tseng, LF1
Delay-Goyet, P; Meucci, E; Roques, BP; Zajac, JM1
Buéno, L; Fioramonti, J1
Livingston, SJ; Rooney, KF; Sewell, RD; Smith, HJ1
Han, JS; Jin, WQ; Zhou, ZF2
Hachisu, M; Hiranuma, T; Murata, S; Shibazaki, Y; Takahashi, H1
Chaillet, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Zajac, JM1
Bean, AJ; Vaught, JL1
Benoist, JM; Gautron, M; Guilbaud, G; Kayser, V1
Guilbaud, G; Kayser, V1
de Groat, WC; Hisamitsu, T1
Harty, GJ; Yaksh, TL1
Costentin, J; Khallouk-Bousselmame, R1
Kishioka, S; Masuda, Y; Miyamoto, Y; Ozaki, M; Yamamoto, H1
Bell, SC; Berend, N; Finnimore, AJ; Matheson, MJ; Rynell, AC1
Dang, VC; Williams, JT1

Reviews

1 review(s) available for thiorphan and morphine

ArticleYear
Enkephalins, other endogenous opioids and colonic motility in dog and man.
    Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:3 Pt 2

    Topics: Animals; Central Nervous System; Colon; Dogs; Endorphins; Enkephalins; Gastrointestinal Motility; Humans; In Vitro Techniques; Morphine; Muscle Contraction; Naloxone; Receptors, Opioid; Species Specificity; Thiorphan; Tiopronin

1987

Other Studies

23 other study(ies) available for thiorphan and morphine

ArticleYear
The effects of orally active enkephalinase inhibitors on morphine withdrawal syndrome.
    Neuroreport, 1992, Volume: 3, Issue:7

    Topics: Administration, Oral; Analgesics; Animals; Dioxolanes; Dipeptides; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Mice; Morphine; Morphine Dependence; Naloxone; Neprilysin; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome; Thiorphan

1992
Attenuation of the morphine withdrawal syndrome by inhibition of catabolism of endogenous enkephalins in the periaqueductal gray matter.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:4

    Topics: Analgesics; Animals; Behavior, Animal; Body Temperature; Body Weight; Corticosterone; Dipeptides; Enkephalins; Hydroxamic Acids; Male; Morphine; Morphine Dependence; Naloxone; Neprilysin; Periaqueductal Gray; Phenylalanine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Thiorphan

1992
Desensitization of mu-opioid receptors does not modify the analgesia induced by an enkephalinase inhibitor.
    European journal of pharmacology, 1991, Oct-15, Volume: 203, Issue:2

    Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Morphine; Neprilysin; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thiorphan

1991
Effect of neutral endopeptidase inhibition of f-Met-Leu-Phe-induced bronchoconstriction in the rabbit.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 70, Issue:2

    Topics: Airway Resistance; Animals; Atropine; Bronchi; Glycopeptides; Morphine; N-Formylmethionine Leucyl-Phenylalanine; Neprilysin; Rabbits; Thiorphan

1991
Modulation of neurogenic inflammation in rat trachea.
    Pulmonary pharmacology, 1990, Volume: 3, Issue:4

    Topics: Albuterol; Animals; Cromolyn Sodium; Dexamethasone; Electric Stimulation; Inflammation; Male; Methysergide; Morphine; Rats; Theophylline; Thiorphan; Trachea; Vagus Nerve

1990
Intrathecal administration of thiorphan, bestatin, desipramine and fluoxetine differentially potentiate the antinociceptive effects induced by beta-endorphin and morphine, administered intracerebroventricularly.
    Neuropharmacology, 1990, Volume: 29, Issue:3

    Topics: Analgesics; Animals; beta-Endorphin; Desipramine; Fluoxetine; Injections, Intraventricular; Injections, Spinal; Leucine; Male; Mice; Mice, Inbred ICR; Morphine; Reaction Time; Thiorphan

1990
Effects of the enkephalinase inhibitor SCH 34826 on the sleep-waking cycle and EEG activity in the rat.
    Neuropharmacology, 1990, Volume: 29, Issue:3

    Topics: Animals; Dioxolanes; Dioxoles; Dipeptides; Dose-Response Relationship, Drug; Electroencephalography; Male; Morphine; Naltrexone; Neprilysin; Rats; Rats, Inbred Strains; Sleep; Sleep, REM; Thiorphan; Wakefulness

1990
Release of a dynorphin A (1-8) degrading enzyme from the spinal cord by intraventricular morphine in the rat.
    Life sciences, 1988, Volume: 42, Issue:13

    Topics: Animals; Aprotinin; Bacitracin; Binding, Competitive; Dynorphins; Injections, Intraventricular; Kinetics; Male; Morphine; Neuropeptides; Peptide Fragments; Peptide Hydrolases; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Tiopronin

1988
Binding in vivo of selective mu and delta opioid receptor agonists: opioid receptor occupancy by endogenous enkephalins.
    European journal of pharmacology, 1989, Nov-21, Volume: 171, Issue:2-3

    Topics: Animals; Brain; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydroxamic Acids; In Vitro Techniques; Injections; Kinetics; Male; Mice; Morphine; Oligopeptides; Phenylalanine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thiorphan

1989
Amelioration of naloxone-precipitated opioid withdrawal symptoms by peripheral administration of the enkephalinase inhibitor acetorphan.
    Psychopharmacology, 1988, Volume: 94, Issue:4

    Topics: Amino Acids, Sulfur; Analgesics; Animals; Body Temperature; Body Weight; Male; Metalloendopeptidases; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Neprilysin; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Thiorphan; Tiopronin

1988
Electroacupuncture and morphine analgesia potentiated by bestatin and thiorphan administered to the nucleus accumbens of the rabbit.
    Brain research, 1986, Aug-20, Volume: 380, Issue:2

    Topics: Amino Acids, Sulfur; Analgesia; Animals; Dose-Response Relationship, Drug; Enkephalin, Methionine; Immune Sera; Leucine; Male; Microinjections; Morphine; Naloxone; Nucleus Accumbens; Rabbits; Septal Nuclei; Thiorphan; Time Factors; Tiopronin; Transcutaneous Electric Nerve Stimulation

1986
Relationship between enkephalinase inhibition of thiorphan in vivo and its analgesic activity.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:9

    Topics: Amino Acids, Sulfur; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Brain; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Morphine; Neprilysin; Nerve Tissue Proteins; Nociceptors; Protease Inhibitors; Rats; Rats, Inbred Strains; Reaction Time; Thiorphan; Tiopronin

1985
[Inhibition of enkephalins degradation in the nucleus accumbens leads to potentiation of acupuncture and morphine analgesia].
    Sheng li xue bao : [Acta physiologica Sinica], 1985, Volume: 37, Issue:4

    Topics: Acupuncture Therapy; Aminopeptidases; Analgesia; Animals; Electric Stimulation Therapy; Endopeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Morphine; Neprilysin; Nucleus Accumbens; Protease Inhibitors; Rabbits; Septal Nuclei; Thiorphan; Tiopronin; Transcutaneous Electric Nerve Stimulation

1985
The mu rather than the delta subtype of opioid receptors appears to be involved in enkephalin-induced analgesia.
    European journal of pharmacology, 1984, May-18, Volume: 101, Issue:1-2

    Topics: Analgesics; Animals; Enkephalin, Leucine; Enkephalins; Guinea Pigs; In Vitro Techniques; Leucine; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Nalorphine; Naloxone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thiorphan; Tiopronin

1984
Physical dependence produced by chronic intracerebroventricular infusion of [D-Arg]kyotorphin or thiorphan to rats.
    European journal of pharmacology, 1984, Oct-15, Volume: 105, Issue:3-4

    Topics: Amino Acids, Sulfur; Analgesics; Animals; Cerebral Ventricles; Endorphins; Humans; Male; Morphine; Naloxone; Neprilysin; Opioid-Related Disorders; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance Withdrawal Syndrome; Thiorphan; Tiopronin

1984
Depressive effects of morphine and of an enkephalinase inhibitor on responses of ventro-basal thalamic neurones to noxious stimuli.
    Life sciences, 1983, Volume: 33 Suppl 1

    Topics: Amino Acids, Sulfur; Animals; Morphine; Neprilysin; Neurons; Nociceptors; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Thalamus; Thiorphan; Tiopronin

1983
The analgesic effects of morphine, but not those of the enkephalinase inhibitor thiorphan, are enhanced in arthritic rats.
    Brain research, 1983, May-09, Volume: 267, Issue:1

    Topics: Amino Acids, Sulfur; Analgesia; Animals; Arthritis; Arthritis, Experimental; Male; Morphine; Naloxone; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Sensory Thresholds; Thiorphan; Tiopronin; Vocalization, Animal

1983
The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat.
    Brain research, 1984, Apr-23, Volume: 298, Issue:1

    Topics: Animals; Cats; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Morphine; Naloxone; Oligopeptides; Reflex; Thiorphan; Tiopronin; Urination

1984
Effects of thiorphan on the antinociceptive actions of intrathecal [D-Ala2,Met5] enkephalin.
    European journal of pharmacology, 1982, Apr-23, Volume: 79, Issue:3-4

    Topics: Amino Acids, Sulfur; Analgesics; Animals; Captopril; Drug Interactions; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Injections, Spinal; Macaca; Morphine; Neprilysin; Protease Inhibitors; Rats; Species Specificity; Thiorphan; Tiopronin

1982
Locomotor and analgesic effects of morphine and acetorphan in rats chronically treated with morphine or thiorphan.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:2

    Topics: Analgesics; Animals; Drug Tolerance; Injections, Intraventricular; Male; Morphine; Motor Activity; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiorphan

1994
Effect of some peptidase inhibitors on exogenous and endogenous opioid actions in guinea-pig ileum.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:1

    Topics: Aminopeptidases; Animals; Bacitracin; Captopril; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; Leucine; Male; Morphine; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Thiorphan

1994
Inhaled FMLP increases microvascular permeability in the rabbit trachea.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:3

    Topics: Administration, Inhalation; Angiotensin II; Animals; Atropine; Blood Pressure; Capillary Permeability; Evans Blue; Male; Morphine; N-Formylmethionine Leucyl-Phenylalanine; Naloxone; Neprilysin; Rabbits; Regional Blood Flow; Thiorphan; Trachea

1993
Chronic morphine treatment reduces recovery from opioid desensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-01, Volume: 24, Issue:35

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methionine; Leucine; Locus Coeruleus; Male; Monensin; Morphine; Morphine Dependence; Morphine Derivatives; Norepinephrine; Phosphorylation; Prazosin; Protein Kinase C; Protein Processing, Post-Translational; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Staurosporine; Thiorphan; Yohimbine

2004