thiorphan has been researched along with enkephalin, leucine-2-alanine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beaumont, A; Ficheux, D; Fournié-Zaluski, MC; Lucas, E; Michel, JB; Roques, BP; Soleilhac, JM; Turcaud, S | 1 |
| Barbe, B; Beaumont, A; Boileau, G; Crine, P; Fournié-Zaluski, MC; Le Moual, H; Roques, BP | 1 |
| Borson, DB; Djokic, TD; Nadel, JA; Sekizawa, K | 1 |
| Gonzalez, JP; Sewell, RD; Smith, HJ; Williams, PS | 1 |
| Martinez, JL; Weinberger, SB | 1 |
| de Groat, WC; Hisamitsu, T | 1 |
| Boileau, G; Crine, P; Dion, N; Fournié-Zaluski, MC; Le Moual, H; Roques, BP | 1 |
| Bawab, W; Crine, P; Fournié-Zaluski, MC; Landry, C; Roques, BP; Santagata, P; Vinay, P | 1 |
| Haberstock, H; Marotti, T | 1 |
| Hoang, MV; Sansom, CE; Turner, AJ | 1 |
| Boileau, G; Carpentier, M; Crine, P; Desgroseillers, L; Ghaddar, G; Marcinkiewicz, M; Ruchon, AF; Seidah, NG | 1 |
| Fournel, S; Nano, JL; Rampal, P | 1 |
12 other study(ies) available for thiorphan and enkephalin, leucine-2-alanine
| Article | Year |
|---|---|
A 94-kDa protein, identified as neutral endopeptidase-24.11, can inactivate atrial natriuretic peptide in the vascular endothelium.
Topics: Amino Acid Sequence; Animals; Atrial Natriuretic Factor; Autoradiography; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enkephalin, Leucine-2-Alanine; Humans; In Vitro Techniques; Molecular Sequence Data; Neprilysin; Rats; Sulfhydryl Compounds; Thiorphan | 1992 |
Charge polarity reversal inverses the specificity of neutral endopeptidase-24.11.
Topics: Binding Sites; Cell Line; DNA; Electrochemistry; Enkephalin, Leucine-2-Alanine; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Substrate Specificity; Sulfhydryl Compounds; Thiorphan | 1992 |
Neutral endopeptidase inhibitors potentiate substance P-induced contraction in gut smooth muscle.
Topics: Animals; Drug Synergism; Duodenum; Endopeptidases; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Ferrets; Glycopeptides; Ileum; Intestines; Male; Muscle Contraction; Protease Inhibitors; Rats; Substance P; Thiorphan | 1989 |
Novel inhibitors of enkephalin-degrading enzymes. I: Inhibitors of enkephalinase by penicillins.
Topics: Analgesics; Animals; Brain; Enkephalin, Leucine-2-Alanine; Isoenzymes; Male; Mice; Mice, Inbred Strains; Naltrexone; Neprilysin; Pain; Penicillins; Thiorphan; Time Factors | 1989 |
Characterization of hydrolysis of [leu]enkephalin and D-ala2-[L-leu]enkephalin in rat plasma.
Topics: Aminopeptidases; Animals; CD13 Antigens; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Half-Life; Hydrolysis; Leucine; Male; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Thiorphan | 1988 |
The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat.
Topics: Animals; Cats; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Morphine; Naloxone; Oligopeptides; Reflex; Thiorphan; Tiopronin; Urination | 1984 |
Evidence that Asn542 of neprilysin (EC 3.4.24.11) is involved in binding of the P2' residue of substrates and inhibitors.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cell Line; Chlorocebus aethiops; Consensus Sequence; Enkephalin, Leucine-2-Alanine; Gene Expression Regulation, Enzymologic; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Neprilysin; Protease Inhibitors; Sequence Alignment; Substrate Specificity; Thermolysin; Thiorphan; Transfection | 1995 |
Characterization of neutral endopeptidase 24.11 in dog glomeruli.
Topics: Animals; Antibodies, Monoclonal; Autoradiography; Blotting, Western; Dogs; Enkephalin, Leucine-2-Alanine; gamma-Aminobutyric Acid; Glycopeptides; Glycosylation; Immunoblotting; Iodobenzenes; Kidney Glomerulus; Kidney Tubules, Proximal; Microvilli; Neprilysin; Octoxynol; Polyethylene Glycols; Thiorphan | 1993 |
The relevance of intact enkephalin molecule in predominantly delta opioid receptor mediated superoxide anion release.
Topics: Adult; Anions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Neprilysin; Neutrophils; Oligopeptides; Protease Inhibitors; Receptors, Opioid, delta; Superoxides; Thiorphan | 1995 |
Mutagenesis of Glu403 to Cys in rabbit neutral endopeptidase-24.11 (neprilysin) creates a disulphide-linked homodimer: analogy with endothelin-converting enzyme.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid Endopeptidases; COS Cells; Cystine; Dimerization; Disulfides; Endothelin-Converting Enzymes; Enkephalin, Leucine-2-Alanine; Glutamic Acid; Glycopeptides; Humans; Immunoblotting; Kinetics; Metalloendopeptidases; Molecular Sequence Data; Mutagenesis, Site-Directed; Neprilysin; Oligopeptides; Protease Inhibitors; Protein Conformation; Rabbits; Rats; Thiorphan | 1997 |
Molecular cloning and biochemical characterization of a new mouse testis soluble-zinc-metallopeptidase of the neprilysin family.
Topics: Amino Acid Sequence; Animals; Cell Line; Chromatography, High Pressure Liquid; Cloning, Molecular; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glycopeptides; Glycosylation; Humans; In Situ Hybridization; Inhibitory Concentration 50; Male; Metalloendopeptidases; Mice; Molecular Sequence Data; Neprilysin; Organ Specificity; Protein Processing, Post-Translational; RNA, Messenger; Sequence Alignment; Solubility; Subtilisin; Testis; Thiorphan; Transfection; Zinc | 2000 |
Characterization of delta-opioid receptors and effect of enkephalins on IRD 98 rat epithelial intestinal cell line.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Cell Line; Cholera Toxin; Cyclic AMP; Dextrorphan; Enkephalin, Leucine-2-Alanine; Enkephalins; Epithelial Cells; Excitatory Amino Acid Antagonists; Fetus; Intestinal Secretions; Intestines; Kinetics; Levorphanol; Naltrexone; Narcotic Antagonists; Neprilysin; Protease Inhibitors; Rats; Receptors, Opioid, delta; Stereoisomerism; Thiorphan; Tritium | 2000 |