thiorphan and cyclic gmp

thiorphan has been researched along with cyclic gmp in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (9.09)	18.7374
1990's	15 (68.18)	18.2507
2000's	5 (22.73)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Corvol, P; el Amrani, AI; Fournié-Zaluski, MC; Michel, JB; Pham, I; Roques, B	1
Bralet, J; Gros, C; Mossiat, C; Schwartz, JC	1
Duboc, D; Fouchard, J; Guérin, F; Muffat-Joly, M; Schwartz, JC; Varin, J; Weber, S	1
Ardaillou, R; Bodin, F; Dussaule, JC; Grangé, JD; Gros, C; Lecomte, JM; Schwartz, JC; Wolf, JP	1
Bralet, J; Danvy, D; Duhamel, L; Duhamel, P; Gros, C; Lecomte, JM; Noël, N; Plaquevent, JC; Schwartz, JC; Souque, A	1
Ardaillou, R; Baumer, P; Chaignon, B; Cournot, A; Duchier, J; Dussaule, JC; Gros, C; Lecomte, JM; Lim, C; Souque, A	1
Needleman, P; Settle, SL; Stockmann, PT; Wilkins, MR	1
McMartin, C; McNeal, RB; Webb, RL; Yasay, GD; Zimmerman, MB	1
Anderson, S; Brenner, BM; Gunning, M; Lafferty, HM; Silva, P; Zimmerman, MB	1
Dressel, J; Hirth-Dietrich, C; Kazda, S; Stasch, JP; Voges, KP; Wegner, M	1
Cernacek, P; Mulay, S; Omer, S; Varma, DR	1
Ardaillou, R; Dussaule, JC; Gros, C; Lecomte, JM; Michel, C; Mignon, F; Peraldi, MN	1
Doucet, J; Fournie-Zaluski, MC; Gonzalez, W; Michel, JB; Pham, I; Roques, BP	1
Ganten, D; Stasch, JP; Wegner, M	1
Anastasopoulos, F; Briscoe, TA; Campbell, DJ; Duncan, AM; James, GM; Kladis, A	1
Hashimoto, Y; Inui, K; Itoh, H; Nakao, K; Ozaki, J; Shimizu, H	1
Agata, J; Higashiura, K; Nanba, M; Shimamoto, K; Takada, M; Takagawa, Y; Torii, T; Ura, N	1
Bryant, HJ; Chen, S; Ghai, RD; Haddy, FJ; Pamnani, MB; Schooley, JF	1
Beals, S; Hanson, B; Kutas, SM; Olivier, NB; Windram, S	1
Brandenberger, G; Charloux, A; Doutreleau, S; Geny, B; Hannedouche, T; Piquard, F; Richard, R	1
Gerbes, AL; Lee, SS; Li, Y; Liu, H; Park, KS; Swain, MG; Zhang, Y	1
Berlan, M; Galitzky, J; Klimcakova, E; Lafontan, M; Moro, C	1

Reviews

1 review(s) available for thiorphan and cyclic gmp

Article	Year
[Effect of sinorphan, an endopeptidase inhibitor on severe congestive cardiac insufficiency]. Archives des maladies du coeur et des vaisseaux, 1991, Volume: 84, Issue:10 Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Cyclic GMP; Diuresis; Female; Heart Failure; Humans; Male; Middle Aged; Natriuresis; Neprilysin; Thiorphan	1991

Trials

5 trial(s) available for thiorphan and cyclic gmp

Article	Year
[Effect of sinorphan, an endopeptidase inhibitor on severe congestive cardiac insufficiency]. Archives des maladies du coeur et des vaisseaux, 1991, Volume: 84, Issue:10 Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Cyclic GMP; Diuresis; Female; Heart Failure; Humans; Male; Middle Aged; Natriuresis; Neprilysin; Thiorphan	1991
Effect of sinorphan, an enkephalinase inhibitor, on plasma atrial natriuretic factor and sodium urinary excretion in cirrhotic patients with ascites. The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:3 Topics: Administration, Oral; Adult; Aldosterone; Atrial Natriuretic Factor; Cyclic GMP; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Liver Cirrhosis; Male; Middle Aged; Neprilysin; Renin; Sodium; Thiorphan	1991
Stereoselective protection of exogenous and endogenous atrial natriuretic factor by enkephalinase inhibitors in mice and humans. European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2 Topics: Administration, Oral; Adult; Animals; Atrial Natriuretic Factor; Binding, Competitive; Chemical Phenomena; Chemistry; Cyclic GMP; Double-Blind Method; Humans; Injections, Intravenous; Kidney; Male; Mice; Neprilysin; Random Allocation; Thiorphan; Time Factors	1990
Inhibition of neutral endopeptidase stimulates renal sodium excretion in patients with chronic renal failure. Clinical science (London, England : 1979), 1993, Volume: 84, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Atrial Natriuretic Factor; Cyclic GMP; Double-Blind Method; Female; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Neprilysin; Sodium; Sodium, Dietary; Thiorphan; Time Factors	1993
Hormonal, renal, hemodynamic responses to acute neutral endopeptidase inhibition in heart transplant patients. Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 93, Issue:2 Topics: Adult; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Cyclosporine; Double-Blind Method; Endothelin-1; Glomerular Filtration Rate; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Natriuresis; Neprilysin; Protease Inhibitors; Renal Circulation; Thiorphan; Vascular Resistance	2002

Other Studies

17 other study(ies) available for thiorphan and cyclic gmp

Article	Year
Effects of the selective neutral endopeptidase inhibitor, retrothiorphan, on renal function and blood pressure in conscious normotensive Wistar and hypertensive DOCA-salt rats. Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:6 Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Bradykinin; Cyclic GMP; Desoxycorticosterone; Diuresis; Hypertension; Kidney; Kininogens; Male; Natriuresis; Neprilysin; Rats; Rats, Wistar; Sulfhydryl Compounds; Thiorphan	1992
Thiorphan-induced natriuresis in volume-expanded rats: roles of endogenous atrial natriuretic factor and kinins. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3 Topics: Animals; Antibodies; Atrial Function; Atrial Natriuretic Factor; Bradykinin; Cardiac Volume; Cyclic GMP; Kidney; Kinins; Male; Natriuresis; Neprilysin; Rats; Rats, Inbred Strains; Thiorphan	1991
Mixed inhibitors of angiotensin-converting enzyme (EC 3.4.15.1) and enkephalinase (EC 3.4.24.11): rational design, properties, and potential cardiovascular applications of glycopril and alatriopril. Proceedings of the National Academy of Sciences of the United States of America, 1991, May-15, Volume: 88, Issue:10 Topics: Alanine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Pressure; Cell Membrane; Cyclic GMP; Dioxoles; Dipeptides; Diuresis; Glycine; Humans; Lung; Male; Mice; Molecular Structure; Natriuresis; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Thiorphan	1991
Maximizing the natriuretic effect of endogenous atriopeptin in a rat model of heart failure. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:16 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antibodies, Monoclonal; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Disease Models, Animal; Heart Failure; Male; Purinones; Rats; Rats, Inbred Strains; Reference Values; Sodium; Thiorphan	1990
Degradation of atrial natriuretic peptide: pharmacologic effects of protease EC 24.11 inhibition. Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:2 Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Glycopeptides; Heart Rate; In Vitro Techniques; Kidney; Male; Protease Inhibitors; Rats; Rats, Inbred SHR; Sodium; Thiorphan; Time Factors	1989
Enkephalinase inhibition increases plasma atrial natriuretic peptide levels, glomerular filtration rate, and urinary sodium excretion in rats with reduced renal mass. Circulation research, 1989, Volume: 65, Issue:3 Topics: Animals; Anti-Bacterial Agents; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Glomerular Filtration Rate; Glycopeptides; Kidney; Male; Nephrectomy; Neprilysin; Rats; Rats, Inbred Strains; Reference Values; Sodium; Thiorphan	1989
Interaction of a neutral endopeptidase inhibitor with an ANP-C receptor ligand in anesthetized dogs. Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:6 Topics: Animals; Atrial Natriuretic Factor; Cardiovascular Diseases; Cyclic GMP; Diuresis; Dogs; Drug Interactions; Female; Kidney; Ligands; Natriuresis; Neprilysin; Oligopeptides; Protease Inhibitors; Receptors, Atrial Natriuretic Factor; Renin; Thiorphan	1995
Attenuation of renal effects of atrial natriuretic factor during rat pregnancy. The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2 Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Diuresis; Female; Glomerular Filtration Rate; Kidney; Natriuresis; Peptide Fragments; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Thiorphan	1995
Effects of angiotensin-converting enzyme and neutral endopeptidase inhibitors: influence of bradykinin. European journal of pharmacology, 1996, Feb-05, Volume: 296, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Cyclic GMP; Enalaprilat; Hypertension; Kidney; Male; Neprilysin; Rats; Rats, Wistar; Thiorphan	1996
Neutral endopeptidase inhibition potentiates the effects of natriuretic peptides in renin transgenic rats. Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:4 Topics: Animals; Animals, Genetically Modified; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Disease Models, Animal; Drug Therapy, Combination; Electrolytes; Hypertension; Mice; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type; Neprilysin; Protease Inhibitors; Proteins; Rats; Rats, Sprague-Dawley; Renin; Sodium; Thiorphan	1996
Interaction between neutral endopeptidase and angiotensin converting enzyme inhibition in rats with myocardial infarction: effects on cardiac hypertrophy and angiotensin and bradykinin peptide levels. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:1 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Bradykinin; Cardiomegaly; Cyclic GMP; Drug Synergism; Indoles; Male; Myocardial Infarction; Neprilysin; Peptidyl-Dipeptidase A; Perindopril; Potassium; Protease Inhibitors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin; Sodium; Thiorphan	1999
Enzymatic inactivation of major circulating forms of atrial and brain natriuretic peptides. European journal of pharmacology, 1999, Apr-16, Volume: 370, Issue:3 Topics: Animals; Atrial Natriuretic Factor; Cell Culture Techniques; Cyclic GMP; Glycopeptides; Humans; LLC-PK1 Cells; Male; Natriuresis; Neprilysin; Nitrobenzenes; Protease Inhibitors; Rats; Rats, Wistar; Swine; Thiorphan	1999
The contribution of nitric oxide to diuretic and natriuretic effects of renal kinins in normotensive rats. Hypertension research : official journal of the Japanese Society of Hypertension, 1999, Volume: 22, Issue:2 Topics: Animals; Blood Pressure; Cyclic GMP; Diuresis; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Kinins; Male; Natriuresis; Neprilysin; Nitric Oxide; Rats; Rats, Sprague-Dawley; Renal Circulation; Second Messenger Systems; Thiorphan; Urodynamics	1999
Effects of a neutral endoprotease enzyme inhibitor, thiorphan, on hemodynamics and renal excretory function in four models of experimental hypertension. Clinical and experimental hypertension (New York, N.Y. : 1993), 2000, Volume: 22, Issue:1 Topics: Animals; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Cyclic GMP; Hypertension; Infusions, Intravenous; Kidney; Male; Potassium; Protease Inhibitors; Rats; Rats, Inbred SHR; Sodium; Thiorphan; Urodynamics	2000
Short-term effects of ecadotril in dogs with induced congestive heart failure. American journal of veterinary research, 2000, Volume: 61, Issue:3 Topics: Animals; Cyclic GMP; Dog Diseases; Dogs; Electrocardiography; Heart Failure; Hemodynamics; Male; Microspheres; Potassium; Protease Inhibitors; Random Allocation; Sodium; Thiorphan	2000
Effects of the neutral endopeptidase inhibitor thiorphan on cardiovascular and renal function in cirrhotic rats. British journal of pharmacology, 2003, Volume: 139, Issue:1 Topics: Animals; Atrial Natriuretic Factor; Cardiovascular Physiological Phenomena; Cyclic GMP; Endothelin-1; Glomerular Filtration Rate; Hemodynamics; Kidney; Liver Cirrhosis, Experimental; Natriuresis; Neprilysin; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Sodium-Potassium-Exchanging ATPase; Thiorphan	2003
Phosphodiesterase-5A and neutral endopeptidase activities in human adipocytes do not control atrial natriuretic peptide-mediated lipolysis. British journal of pharmacology, 2007, Volume: 152, Issue:7 Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adult; Atrial Natriuretic Factor; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Humans; Kinetics; Lipolysis; Neprilysin; Phosphodiesterase 5 Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiorphan; Time Factors	2007