thiorphan has been researched along with bradykinin in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.06) | 18.7374 |
| 1990's | 24 (72.73) | 18.2507 |
| 2000's | 6 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Corvol, P; el Amrani, AI; Fournié-Zaluski, MC; Michel, JB; Pham, I; Roques, B | 1 |
| Conlon, JM; Gao, XP; Koizumi, S; Mayhan, WG; Rennard, SI; Rubinstein, I; Yong, T | 1 |
| Abraham, WM; Ahmed, A; Burch, RM; Caplan, J; Cortes, A; Mansour, E | 1 |
| Bertrand, C; Da Silva, A; Dhuy, J; Landry, Y; Waeldelé, F | 1 |
| Håkanson, R; Wang, ZY | 1 |
| Bralet, J; Gros, C; Mossiat, C; Schwartz, JC | 1 |
| Hayakawa, H; Hirata, Y; Kangawa, K; Matsuo, H; Matsuoka, H; Sugimoto, T; Suzuki, E | 1 |
| Chiu, PJ; Sybertz, EJ; Vemulapalli, S; Watkins, RW | 1 |
| Del Bianco, E; Geppetti, P; Maggi, CA; Santicioli, P; Tramontana, M; Ziche, M | 1 |
| McGraw, DE; Smits, GJ; Trapani, AJ | 1 |
| Cecconi, R; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Cohen, ML; Geary, LE; Scott, WL; Wiley, KS | 1 |
| Amrani, Y; Da Silva, A; Landry, Y; Trifilieff, A | 1 |
| Botyánszki, J; Fehér, E; Hepp, J; Magyar, A; Medzihradszky, K; Rónai, AZ | 1 |
| Broom, T; DeSiato, MA; Farmer, SG | 1 |
| Kitano, S; Webber, SE; Wells, UM; Widdicombe, JG; Yurdakos, E | 1 |
| Doucet, J; Fournie-Zaluski, MC; Gonzalez, W; Michel, JB; Pham, I; Roques, BP | 1 |
| Hoang, MV; Turner, AJ | 1 |
| Gao, XP; Olopade, CO; Pakhlevaniants, S; Rubinstein, I; Suzuki, H | 1 |
| Adam, A; Blais, C; Drapeau, G; Gervais, N; Lamontagne, D; Raymond, P; Venneman, I | 1 |
| Hintze, TH; Nasjletti, A; Xu, X; Zhang, X | 1 |
| Adam, A; Blais, C; Dumoulin, MJ; Lamontagne, D | 1 |
| Anastasopoulos, F; Briscoe, TA; Campbell, DJ; Duncan, AM; James, GM; Kladis, A | 1 |
| Hayashi, I; Ito, H; Izumi, T; Katori, M; Majima, M; Nakajima, S | 1 |
| Hintze, TH; Kaley, G; Kichuk, MR; Michler, R; Mital, S; Nasjletti, A; Oz, M; Zhang, X | 1 |
| Addonizio, L; Bernstein, R; Hintze, TH; Kaley, G; Laycock, SK; Loke, KE; Mital, S; Oz, M; Wolin, MS | 1 |
| Arbin, V; Claperon, N; Fournié-Zaluski, MC; Peyroux, J; Roques, BP | 1 |
| Miyamoto, A; Murata, S; Nishio, A | 1 |
| Ansai, T; Awano, S; Carson, JA; Takehara, T; Turner, AJ; Yu, W | 1 |
| Krassói, I; Papp, JG; Pataricza, J | 1 |
| Brooks, DP; Edwards, RM; Pullen, MA; Sulpizio, AC | 1 |
| Cruden, NL; Fox, KA; Johnston, NR; Ludlam, CA; Newby, DE | 1 |
| Acharya, KR; Cozier, GE; Sharma, U; Sturrock, ED | 1 |
1 trial(s) available for thiorphan and bradykinin
| Article | Year |
|---|---|
Neutral endopeptidase inhibition augments vascular actions of bradykinin in patients treated with angiotensin-converting enzyme inhibition.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Bradykinin; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Heart Failure; Humans; Male; Middle Aged; Neprilysin; Nitroprusside; Protease Inhibitors; Receptor, Bradykinin B1; Thiorphan; Tissue Plasminogen Activator; Vasodilation; Vasodilator Agents | 2004 |
32 other study(ies) available for thiorphan and bradykinin
| Article | Year |
|---|---|
Effects of the selective neutral endopeptidase inhibitor, retrothiorphan, on renal function and blood pressure in conscious normotensive Wistar and hypertensive DOCA-salt rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Bradykinin; Cyclic GMP; Desoxycorticosterone; Diuresis; Hypertension; Kidney; Kininogens; Male; Natriuresis; Neprilysin; Rats; Rats, Wistar; Sulfhydryl Compounds; Thiorphan | 1992 |
Role of peptidases in bradykinin-induced increase in vascular permeability in vivo.
Topics: Animals; Bradykinin; Capillary Permeability; Captopril; Cheek; Cricetinae; Glycopeptides; Inflammation; Microcirculation; Neprilysin; Peptidyl-Dipeptidase A; Thiorphan | 1992 |
Mechanisms of metabisulfite-induced bronchoconstriction: evidence for bradykinin B2-receptor stimulation.
Topics: Animals; Asthma; Bradykinin; Bronchoconstriction; Food Preservatives; Receptors, Bradykinin; Receptors, Neurotransmitter; Sheep; Sulfites; Thiorphan | 1992 |
Endopeptidase 24.15 modulates bradykinin-induced contraction in guinea-pig trachea.
Topics: Amino Acid Sequence; Animals; Bradykinin; Dose-Response Relationship, Drug; Guinea Pigs; Male; Metalloendopeptidases; Molecular Sequence Data; Muscle Contraction; Oligopeptides; Peptidyl-Dipeptidase A; Substance P; Thiorphan; Trachea | 1992 |
Effect of resiniferatoxin on the isolated rabbit iris sphincter muscle: comparison with capsaicin and bradykinin.
Topics: Animals; Bradykinin; Capsaicin; Captopril; Diterpenes; Electric Stimulation; Female; Iris; Male; Muscle Contraction; Rabbits; Substance P; Tachykinins; Tachyphylaxis; Thiorphan | 1992 |
Thiorphan-induced natriuresis in volume-expanded rats: roles of endogenous atrial natriuretic factor and kinins.
Topics: Animals; Antibodies; Atrial Function; Atrial Natriuretic Factor; Bradykinin; Cardiac Volume; Cyclic GMP; Kidney; Kinins; Male; Natriuresis; Neprilysin; Rats; Rats, Inbred Strains; Thiorphan | 1991 |
Role of endogenous atrial natriuretic peptide in regulating sodium excretion in spontaneously hypertensive rats. Effects of neutral endopeptidase inhibition.
Topics: Animals; Atrial Natriuretic Factor; Bradykinin; Immune Sera; Male; Natriuresis; Neprilysin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thiorphan | 1991 |
Neutral metalloendopeptidase inhibitors as ANF potentiators: sites and mechanisms of action.
Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Bradykinin; Desoxycorticosterone; Dioxolanes; Dipeptides; Drug Synergism; Hypertension; Iodine Radioisotopes; Kinins; Male; Metalloendopeptidases; Rats; Rats, Inbred Strains; Thiorphan | 1991 |
The effect of thiorphan on release of sensory neuropeptides from guinea-pig cerebral venous sinuses.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cranial Sinuses; Female; Guinea Pigs; Immunoenzyme Techniques; In Vitro Techniques; Male; Neurons, Afferent; Neuropeptides; Radioimmunoassay; Thiorphan | 1991 |
Interaction of ANP and bradykinin during endopeptidase 24.11 inhibition: renal effects.
Topics: Animals; Atrial Natriuretic Factor; Bradykinin; Captopril; Diuretics; Drug Synergism; Kidney; Male; Natriuresis; Neprilysin; Peptide Fragments; Rats; Rats, Inbred Strains; Thiorphan | 1990 |
Multiple mechanisms in the motor responses of the guinea-pig isolated urinary bladder to bradykinin.
Topics: Animals; Apamin; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Indomethacin; Kallidin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Substance P; Tetrodotoxin; Thiorphan; Urinary Bladder | 1989 |
Degradation of exogenous enkephalin in the guinea-pig ileum: relative importance of aminopeptidase, enkephalinase and angiotensin converting enzyme activity.
Topics: Aminopeptidases; Angiotensin I; Animals; Bradykinin; Endopeptidases; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neprilysin; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin | 1982 |
Involvement of B2 receptors in the bradykinin-induced relaxation of guinea-pig isolated trachea.
Topics: Animals; Bradykinin; Dose-Response Relationship, Drug; Guinea Pigs; Male; Melitten; Receptors, Adrenergic, beta-2; Relaxation; Thiorphan; Trachea | 1995 |
Substrate- and inhibitor-specificity of a non-endothelial enzyme which forms [Met5]-enkephalin from [Met5]-enkephalin-Arg6,Phe7 in isolated rabbit ear artery: pharmacological characterization.
Topics: Amino Acid Sequence; Angiotensin I; Animals; Arteries; Bradykinin; Captopril; Disease Models, Animal; Ear, External; Enalapril; Endopeptidases; Endothelium, Vascular; Enkephalin, Methionine; Male; Migraine Disorders; Molecular Sequence Data; Rabbits; Substrate Specificity; Thiorphan | 1995 |
Effects of bradykinin receptor agonists, and captopril and thiorphan in ferret isolated trachea: evidence for bradykinin generation in vitro.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Ferrets; In Vitro Techniques; Male; Muscle Contraction; Receptors, Bradykinin; Thiorphan; Trachea | 1994 |
The effects of indomethacin and thiorphan on bradykinin-induced albumin output and submucosal gland secretion in the ferret trachea in vivo.
Topics: Albumins; Animals; Bradykinin; Female; Ferrets; Indomethacin; Male; Muramidase; Neprilysin; Thiorphan; Trachea | 1993 |
Effects of angiotensin-converting enzyme and neutral endopeptidase inhibitors: influence of bradykinin.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Cyclic GMP; Enalaprilat; Hypertension; Kidney; Male; Neprilysin; Rats; Rats, Wistar; Thiorphan | 1996 |
Novel activity of endothelin-converting enzyme: hydrolysis of bradykinin.
Topics: Animals; Aspartic Acid Endopeptidases; Blotting, Western; Bradykinin; Chelating Agents; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Edetic Acid; Endopeptidases; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glycopeptides; Hydrolysis; Kinetics; Metalloendopeptidases; Peptide Fragments; Rats; Substrate Specificity; Thiorphan | 1997 |
Angiotensin-converting enzyme and neutral endopeptidase modulate smokeless tobacco-induced increase in macromolecular efflux from the oral mucosa in vivo.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Captopril; Cricetinae; Dextrans; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Glycopeptides; Lisinopril; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Neprilysin; Peptidyl-Dipeptidase A; Plants, Toxic; Protease Inhibitors; Thiorphan; Tobacco, Smokeless | 1997 |
Contribution of angiotensin-converting enzyme to the cardiac metabolism of bradykinin: an interspecies study.
Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies; Bradykinin; Cross Reactions; Dogs; Enalaprilat; Humans; Kinetics; Losartan; Myocardium; Peptidyl-Dipeptidase A; Protease Inhibitors; Rabbits; Rats; Species Specificity; Substrate Specificity; Thiorphan | 1997 |
Neutral endopeptidase and angiotensin-converting enzyme inhibitors increase nitric oxide production in isolated canine coronary microvessels by a kinin-dependent mechanism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coronary Vessels; Coumarins; Dogs; Drug Interactions; Glycopeptides; In Vitro Techniques; Isocoumarins; Neprilysin; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Protease Inhibitors; Ramipril; Serine Proteinase Inhibitors; Thiorphan | 1998 |
Metabolism of bradykinin by the rat coronary vascular bed.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Chromatography, High Pressure Liquid; Coronary Circulation; Coronary Vessels; Enalaprilat; Hemodynamics; Immunoenzyme Techniques; In Vitro Techniques; Male; Neprilysin; Perfusion; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Thiorphan; Time Factors | 1998 |
Interaction between neutral endopeptidase and angiotensin converting enzyme inhibition in rats with myocardial infarction: effects on cardiac hypertrophy and angiotensin and bradykinin peptide levels.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Bradykinin; Cardiomegaly; Cyclic GMP; Drug Synergism; Indoles; Male; Myocardial Infarction; Neprilysin; Peptidyl-Dipeptidase A; Perindopril; Potassium; Protease Inhibitors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin; Sodium; Thiorphan | 1999 |
Effect of prolonged administration of a urinary kinase inhibitor, ebelactone B on the development of deoxycorticosterone acetate-salt hypertension in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Carboxypeptidases; Cathepsin A; Desoxycorticosterone; Drinking; Heart; Heart Ventricles; Hypertension; Kallikreins; Kidney; Kinins; Lactones; Lisinopril; Male; Organ Size; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thiorphan; Time Factors; Urination; Water-Electrolyte Balance | 1999 |
Amlodipine promotes kinin-mediated nitric oxide production in coronary microvessels of failing human hearts.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bradykinin Receptor Antagonists; Calcium Channel Blockers; Cardiac Output, Low; Coronary Vessels; Dose-Response Relationship, Drug; Glycopeptides; Humans; Metalloendopeptidases; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Quinine; Ramipril; Serine Proteinase Inhibitors; Thiorphan | 1999 |
Nitric oxide modulates mitochondrial respiration in failing human heart.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Calcium Channel Blockers; Humans; In Vitro Techniques; Mitochondria, Muscle; Myocardium; Neprilysin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Oxygen Consumption; Ramipril; Thiorphan; Vasodilator Agents | 1999 |
Effects of combined neutral endopeptidase 24-11 and angiotensin-converting enzyme inhibition on femoral vascular conductance in streptozotocin-induced diabetic rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Femoral Artery; Hemodynamics; Kininogens; Lysine Carboxypeptidase; Male; Neprilysin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Thiorphan; Time Factors | 2000 |
Role of ACE and NEP in bradykinin-induced relaxation and contraction response of isolated porcine basilar artery.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Basilar Artery; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neprilysin; Peptidyl-Dipeptidase A; Protease Inhibitors; Receptor, Bradykinin B2; Swine; Thiorphan; Vasoconstriction; Vasodilation | 2002 |
Characterization of PgPepO, a bacterial homologue of endothelin-converting enzyme-1.
Topics: Angiotensin I; Angiotensin II; Aspartic Acid Endopeptidases; Bacterial Proteins; Bradykinin; Chromatography, High Pressure Liquid; Endothelin-Converting Enzymes; Enzyme Activation; Enzyme Inhibitors; Glycopeptides; Humans; Hydrolysis; Inhibitory Concentration 50; Metalloendopeptidases; Neurotensin; Porphyromonas gingivalis; Substance P; Thiorphan | 2002 |
Thiorphan enhances bradykinin-induced vascular relaxation in hypoxic/hyperkalaemic porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Coronary Vessels; Drug Synergism; Hyperkalemia; Hypoxia; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Protease Inhibitors; Swine; Thiorphan; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
The effect of acute angiotensin-converting enzyme and neutral endopeptidase 24.11 inhibition on plasma extravasation in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Lung; Male; Neprilysin; Peptidyl-Dipeptidase A; Plasma; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Neurokinin-1; Substance P; Thiorphan | 2004 |
Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin-Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Crystallography, X-Ray; Drug Design; Mesylates; Neprilysin; Peptidyl-Dipeptidase A; Protein Binding; Protein Structure, Secondary; Pyridines; Thiazepines; Tyrosine | 2020 |