thiorphan has been researched along with amyloid beta-peptides in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harigaya, W; Iwata, H; Iwata, N; Iwatsubo, T; Kiryu-Seo, S; Kiyama, H; Maruyama, K; Saido, TC; Shirotani, K; Takaki, Y; Tomita, T; Tsubuki, S | 1 |
| Beach, TG; Newell, AJ; Potter, PE; Rauschkolb, PK; Scott, S; Sue, LI; Walker, DG | 1 |
| Iwata, N; Mizoguchi, H; Mouri, A; Nabeshima, T; Noda, Y; Saido, TC; Wang, D; Wang, MW; Zou, LB | 1 |
| Capetillo-Zarate, E; Gouras, GK; Lin, MT; Rahman, N; Tampellini, D | 1 |
4 other study(ies) available for thiorphan and amyloid beta-peptides
| Article | Year |
|---|---|
Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Base Sequence; Chromosome Mapping; Cloning, Molecular; Endopeptidases; Enzyme Inhibitors; Glycopeptides; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Neprilysin; Neurons; Peptide Fragments; Recombinant Proteins; Substrate Specificity; Thiorphan; X Chromosome | 2001 |
Thiorphan-induced neprilysin inhibition raises amyloid beta levels in rabbit cortex and cerebrospinal fluid.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain Chemistry; Cerebral Cortex; Enzyme-Linked Immunosorbent Assay; Immunoblotting; Immunohistochemistry; Injections, Intraventricular; Neprilysin; Peptide Fragments; Protease Inhibitors; Rabbits; Thiorphan | 2003 |
Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid Beta and impairment of learning and memory.
Topics: Acetylcholine; Amyloid beta-Peptides; Animals; Enzyme Inhibitors; Hippocampus; Infusions, Parenteral; Male; Maze Learning; Memory; Motor Activity; Neprilysin; Nicotine; Peptide Fragments; Rats; Rats, Wistar; Thiorphan | 2006 |
Impaired β-amyloid secretion in Alzheimer's disease pathogenesis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Disks Large Homolog 4 Protein; Electric Stimulation; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Female; Glycine; Guanylate Kinases; Long-Term Potentiation; Male; Membrane Proteins; Mice; Mice, Transgenic; Neurons; Peptide Fragments; Protease Inhibitors; Thiorphan | 2011 |