Page last updated: 2024-08-16

thioridazine and spiperone

thioridazine has been researched along with spiperone in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199019 (65.52)18.7374
1990's6 (20.69)18.2507
2000's2 (6.90)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
George, SR; Guan, HC; Laurier, LG; Ng, G; Niznik, HB; O'Dowd, BF; Seeman, P; Sunahara, RK; Torchia, J; Van Tol, HH1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Andrews, PR; Craik, DJ; Martin, JL1
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Grinde, E; Herrick-Davis, K; Teitler, M1
Glennon, RA1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Artursson, P; Mateus, A; Matsson, P1
Amdur, RL; Carvey, PM; Kao, LC; Klawans, HL; Lin, DH; Nath, ST; Singh, R; Zhang, TJ1
Amato, G; Calzà, L; Giardino, L; Piazza, PV1
Cubeddu, LX; Mailman, RB; Niedzwiecki, DM1
Babb, S; Baldessarini, RJ; Bird, ED; Campbell, A; Cohen, BM; Froimowitz, M; Hrbek, C; Kula, N; Svendsen, CN; Teicher, MH1
Ko, GN; Korpi, ER; Linnoila, M1
Clow, A; Jenner, P; Marsden, CD; Theodorou, A3
Lader, SR1
Carino, MA; Horita, A; Lai, HC1
Carino, MA; Horita, A; Lai, H1
Seeman, P; Ulpian, C1
Angeby, K; Florvall, L; Hall, H; Köhler, C; Lindbom, LO; Magnusson, O; Ogren, SO1
Breese, GR; Kilts, CD; Knight, DL; Mailman, RB; Widerlöv, E1
Crofton, KM; DeHaven, DL; Kilts, CD; Lewis, MH; Mailman, RB; Petitto, J; Pierce, JP1
Bentall, AC; Herberg, LJ1
Angeby, T; Haglund, L; Köhler, C; Ogren, SO1
Herberg, LJ; Wishart, TB1
Smythies, JR1
Assié, MB; Koek, W; Sleight, AJ1

Reviews

2 review(s) available for thioridazine and spiperone

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003
On the clinical relevance and methods of quantification of plasma concentrations of neuroleptics.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:5

    Topics: Animals; Antipsychotic Agents; Binding Sites; Chromatography, Gas; Corpus Striatum; Ethnicity; Follow-Up Studies; Haloperidol; Humans; Kinetics; Orosomucoid; Prolactin; Radioligand Assay; Rats; Schizophrenia; Spiperone; Thioridazine

1985

Other Studies

27 other study(ies) available for thioridazine and spiperone

ArticleYear
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
    Nature, 1991, Apr-18, Volume: 350, Issue:6319

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain; Cell Line; Cell Membrane; Cloning, Molecular; Dopamine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Oligonucleotide Probes; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D5; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection

1991
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin

1994
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1

    Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists

2000
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Clozapine fails to prevent the development of haloperidol-induced behavioral hypersensitivity in a cotreatment paradigm.
    European journal of pharmacology, 1990, Aug-02, Volume: 184, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Binding, Competitive; Brain Chemistry; Clozapine; Corpus Striatum; Dopamine; Drug Interactions; Haloperidol; Male; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior; Thioridazine

1990
Thioridazine chronic administration: a behavioural and autoradiographic study.
    Neuroscience letters, 1990, Feb-05, Volume: 109, Issue:1-2

    Topics: Animals; Apomorphine; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Thioridazine

1990
Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: Acetylcholine; Animals; Antidepressive Agents; Binding, Competitive; Corpus Striatum; Dopamine; Dopamine Antagonists; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mesoridazine; Phenothiazines; Rabbits; Receptors, Dopamine; Spiperone; Thioridazine

1989
Receptor affinity, neurochemistry and behavioral characteristics of the enantiomers of thioridazine: evidence for different stereoselectivities at D1 and D2 receptors in rat brain.
    Neuropharmacology, 1988, Volume: 27, Issue:11

    Topics: Animals; Benzazepines; Brain Chemistry; Catalepsy; Dopamine Antagonists; Male; Norepinephrine; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Muscarinic; Spiperone; Stereoisomerism; Thioridazine

1988
Changes in rat striatal dopamine turnover and receptor activity during one years neuroleptic administration.
    European journal of pharmacology, 1980, May-02, Volume: 63, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Binding Sites; Corpus Striatum; Cyclic AMP; Dopamine; Homovanillic Acid; Male; Rats; Receptors, Dopamine; Spiperone; Thioridazine; Time Factors; Trifluoperazine

1980
Cerebral dopamine function in rats following withdrawal from one year of continuous neuroleptic administration.
    European journal of pharmacology, 1980, May-02, Volume: 63, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Binding Sites; Body Weight; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Male; Motor Activity; Mouth; Movement; Rats; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine; Time Factors; Trifluoperazine

1980
A radioreceptor assay for neuroleptic drugs in plasma.
    Journal of immunoassay, 1980, Volume: 1, Issue:1

    Topics: Animals; Antipsychotic Agents; Binding Sites; Cattle; Chromatography, Gas; Dose-Response Relationship, Drug; Haloperidol; Heparin; Humans; Quality Control; Radioligand Assay; Receptors, Dopamine; Spiperone; Thioridazine

1980
Effects of chronic haloperidol, thioridazine and zotepine treatment on apomorphine elicited stereotypic behavior and 3H-spiroperidol binding sites in the striatum of the rat.
    Proceedings of the Western Pharmacology Society, 1981, Volume: 24

    Topics: Animals; Antipsychotic Agents; Apomorphine; Binding Sites; Butyrophenones; Corpus Striatum; Dibenzothiepins; Haloperidol; Humans; Male; Rats; Spiperone; Stereotyped Behavior; Thioridazine

1981
Chronic treatments with zotepine, thioridazine, and haloperidol affect apomorphine-elicited stereotypic behavior and striatal 3H-spiroperidol binding sites in the rat.
    Psychopharmacology, 1981, Volume: 75, Issue:4

    Topics: Animals; Antipsychotic Agents; Apomorphine; Binding Sites; Butyrophenones; Corpus Striatum; Dibenzothiepins; Drug Interactions; Haloperidol; Humans; Male; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior; Thioridazine

1981
Neuroleptics have identical potencies in human brain limbic and putamen regions.
    European journal of pharmacology, 1983, Oct-14, Volume: 94, Issue:1-2

    Topics: Antipsychotic Agents; Binding, Competitive; Haloperidol; Humans; In Vitro Techniques; Limbic System; Nucleus Accumbens; Putamen; Receptors, Dopamine; Spiperone; Thioridazine

1983
Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain.
    European journal of pharmacology, 1984, Jul-20, Volume: 102, Issue:3-4

    Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzamides; Binding, Competitive; Brain Chemistry; Catalepsy; Chlorpromazine; Dogs; Female; Haloperidol; Histocytochemistry; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Remoxipride; Spiperone; Sulpiride; Thioridazine; Vomiting

1984
Effects of thioridazine and its metabolites on dopaminergic function: drug metabolism as a determinant of the antidopaminergic actions of thioridazine.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Dextroamphetamine; Dopamine; Homovanillic Acid; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Thioridazine

1984
Thioridazine and the neuroleptic radioreceptor assay.
    Biological psychiatry, 1984, Volume: 19, Issue:6

    Topics: Animals; Binding, Competitive; Cattle; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Thioridazine

1984
Changes in cerebral dopamine function induced by a year's administration of trifluoperazine or thioridazine and their subsequent withdrawal.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Brain; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Humans; Male; Rats; Spiperone; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine; Time Factors; Trifluoperazine

1980
Blockade of amphetamine-induced locomotor activity and stereotypy in rats by spiroperidol but not by an atypical neuroleptic, thioridazine.
    Neuropharmacology, 1980, Volume: 19, Issue:8

    Topics: Amphetamine; Animals; Butyrophenones; Humans; Male; Motor Activity; Rats; Spiperone; Stereotyped Behavior; Thioridazine

1980
Regional blockade by neuroleptic drugs of in vivo 3H-spiperone binding in the rat brain. Relation to blockade of apomorphine induced hyperactivity and stereotypies.
    Journal of neural transmission, 1981, Volume: 52, Issue:3

    Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butyrophenones; Chlorpromazine; Clozapine; Haloperidol; Humans; Hyperkinesis; Kinetics; Organ Specificity; Rats; Receptors, Dopamine; Receptors, Drug; Spiperone; Stereotyped Behavior; Sulpiride; Thioridazine

1981
Self-stimulation and locomotor changes indicating "latent" anticholinergic activity by an atypical neuroleptic (thioridazine).
    Neuropharmacology, 1981, Volume: 20, Issue:1

    Topics: Animals; Drug Interactions; Hypothalamus; Male; Motor Activity; Oxotremorine; Parasympatholytics; Rats; Scopolamine; Self Stimulation; Spiperone; Thioridazine

1981
An hypothesis of the molecular structure of the dopamine receptor.
    Medical hypotheses, 1981, Volume: 7, Issue:12

    Topics: Apomorphine; Chemical Phenomena; Chemistry; Dopamine; Neurotensin; Pimozide; Receptors, Cholinergic; Receptors, Dopamine; Spiperone; Thioridazine

1981
Biphasic displacement of [3H]YM-09151-2 binding in the rat brain by thioridazine, risperidone and clozapine, but not by other antipsychotics.
    European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

    Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Clozapine; Corpus Striatum; Dopamine D2 Receptor Antagonists; In Vitro Techniques; Isoxazoles; Male; Olfactory Pathways; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Risperidone; Spiperone; Thioridazine

1993