Page last updated: 2024-08-16

thioridazine and propranolol

thioridazine has been researched along with propranolol in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199014 (38.89)18.7374
1990's2 (5.56)18.2507
2000's8 (22.22)29.6817
2010's12 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Abraham, MH; Acree, WE; Ibrahim, A1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gabriel, E; Karobath, M; Lenz, G1
Fogelholm, R; Kotilainen, P; Lamberg, BA; Linnoila, M; Olkinuora, M; Saarinen, P1
Caine, M; Raz, S1
Hill, DF; Hungen, KV; Roberts, S1
Greendyke, RM; Kanter, DR1
Katz, BL; Kogan, M; Silver, JM; Yudofsky, SC1
Manchanda, R1
Eccleston, D; Fairbairn, AF; Hassanyeh, F; McClelland, HA; Stephens, DA1
Dybing, E1
Del Rio, J; Fuentes, JA1
Hassanein, RS; Lukert, BP; Stein, PM1
Alfredsson, G; Hanssen, T; Heyden, T; Nybäck, H; Sundberg, I; Wetterberg, L1
Lang, C; Remington, D1
Betz, L; Champion, W; Geiser, F; Lee, J; Schultz, M; Shaimi, M1
Maskaoui, K; Zhou, JL1

Reviews

2 review(s) available for thioridazine and propranolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Some clinical implications of adrenergic receptors in the urinary tract.
    Archives of surgery (Chicago, Ill. : 1960), 1975, Volume: 110, Issue:3

    Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Autonomic Agents; Estrogens; Female; Humans; Imipramine; Male; Medroxyprogesterone; Phenoxybenzamine; Phentolamine; Progesterone; Propranolol; Prostate; Prostatitis; Receptors, Adrenergic; Thioridazine; Ureter; Urethra; Urinary Bladder; Urinary Incontinence, Stress; Urinary Tract; Urologic Diseases

1975

Trials

2 trial(s) available for thioridazine and propranolol

ArticleYear
The effect of propranolol and thioridazine on positive and negative symptoms of schizophrenia.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 147

    Topics: Adolescent; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Propranolol; Psychiatric Status Rating Scales; Pulse; Schizophrenia; Schizophrenic Psychology; Thioridazine; Time Factors

1985
Psychopharmacology.
    Acta psychiatrica Scandinavica. Supplementum, 1970, Volume: 217

    Topics: Alcoholism; Anxiety; Brain Damage, Chronic; Chronic Disease; Clinical Trials as Topic; Depression; Ethanol; Humans; Injections, Intramuscular; Meprobamate; Phenothiazines; Piperazines; Propranolol; Psychopharmacology; Reserpine; Retinitis; Schizophrenia; Thioridazine; Trifluoperazine; Xanthenes

1970

Other Studies

32 other study(ies) available for thioridazine and propranolol

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
[The extrapyramidal symptoms in the combination of lithium long-term lithium therapy with nortriptyline. A case report on the formation of a pathogenesis hypothesis].
    Der Nervenarzt, 1976, Volume: 47, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Bipolar Disorder; Chlorprothixene; Clopenthixol; Dibenzazepines; Drug Synergism; Drug Therapy, Combination; Female; Humans; Lithium; Long-Term Care; Nortriptyline; Parkinson Disease; Parkinson Disease, Secondary; Procyclidine; Propranolol; Synapses; Thioridazine

1976
The effect of psychotropic drugs on the TSH-response to thyroliberin (TRH).
    Neuroendocrinology, 1977, Volume: 24, Issue:2

    Topics: Chlorpromazine; Fusaric Acid; Humans; Levodopa; Norepinephrine; Pimozide; Pituitary Gland, Anterior; Propranolol; Psychotropic Drugs; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thioridazine; Thyrotropin; Thyrotropin-Releasing Hormone

1977
Interactions between lysergic acid diethylamide and dopamine-sensitive adenylate cyclase systems in rat brain.
    Brain research, 1975, Aug-22, Volume: 94, Issue:1

    Topics: Adenylyl Cyclases; Animals; Brain; Chlorpromazine; Corpus Striatum; Cyproheptadine; Dopamine; Dose-Response Relationship, Drug; Enzyme Activation; Hallucinogens; Haloperidol; Hippocampus; Lysergic Acid Diethylamide; Male; Methysergide; Norepinephrine; Promethazine; Propranolol; Serotonin; Thioridazine; Trifluoperazine

1975
Plasma propranolol levels and their effect on plasma thioridazine and haloperidol concentrations.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:3

    Topics: Adult; Aged; Drug Interactions; Haloperidol; Humans; Male; Mesoridazine; Middle Aged; Neurocognitive Disorders; Phenothiazines; Propranolol; Thioridazine

1987
Elevation of thioridazine plasma levels by propranolol.
    The American journal of psychiatry, 1986, Volume: 143, Issue:10

    Topics: Adult; Aggression; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Mental Disorders; Propranolol; Prospective Studies; Stimulation, Chemical; Thioridazine

1986
Criteria for measuring change: statistical significance vs clinical significance.
    The British journal of psychiatry : the journal of mental science, 1986, Volume: 148

    Topics: Humans; Propranolol; Schizophrenia; Thioridazine

1986
Effects of membrane stabilizers on glucuronidation and amino acid transport in cultures of rat hepatoma cells.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:6

    Topics: Alanine; Aminoisobutyric Acids; Animals; Antipsychotic Agents; Biological Transport; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Depression, Chemical; Glucuronates; Imipramine; Liver Neoplasms; Promazine; Propranolol; Protein Binding; Rats; Thioridazine

1973
Further studies on the antagonism of stereotyped behaviour induced by amphetamine.
    European journal of pharmacology, 1969, Volume: 8, Issue:1

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Benperidol; Chlorpromazine; Exploratory Behavior; Haloperidol; Male; Perphenazine; Phenothiazines; Phenoxybenzamine; Phentolamine; Pilocarpine; Promazine; Propranolol; Rats; Thioridazine; Tremorine; Trifluperidol

1969
Predicting weight loss success among obese clients in a hospital nutrition clinic.
    The American journal of clinical nutrition, 1981, Volume: 34, Issue:10

    Topics: Adolescent; Adult; Age Factors; Aged; Ambulatory Care Facilities; Body Weight; Estrogens, Conjugated (USP); Female; Humans; Male; Middle Aged; Obesity; Prognosis; Propranolol; Regression Analysis; Retrospective Studies; Sex Factors; Thioridazine

1981
Propranolol in schizophrenia. Clinical, metabolic, and pharmacological findings.
    Archives of general psychiatry, 1980, Volume: 37, Issue:6

    Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Melatonin; Middle Aged; Prolactin; Propranolol; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Thioridazine

1980
Treatment with propranolol of severe self-injurious behavior in a blind, deaf, retarded adolescent.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1994, Volume: 33, Issue:2

    Topics: Activities of Daily Living; Adolescent; Arousal; Blindness; Deafness; Drug Therapy, Combination; Education of Intellectually Disabled; Female; Humans; Neurologic Examination; Propranolol; Self-Injurious Behavior; Thioridazine

1994
Direct, preparative enantioselective chromatography of propranolol hydrochloride and thioridazine hydrochloride using carbon dioxide-based mobile phases.
    Journal of chromatography. A, 1999, Dec-31, Volume: 865, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Antipsychotic Agents; Carbon Dioxide; Chromatography; Mass Spectrometry; Methanol; Propranolol; Stereoisomerism; Thioridazine

1999
Colloids as a sink for certain pharmaceuticals in the aquatic environment.
    Environmental science and pollution research international, 2010, Volume: 17, Issue:4

    Topics: Carbamazepine; Colloids; Diclofenac; Environmental Restoration and Remediation; Fresh Water; Indomethacin; Meclofenamic Acid; Pharmaceutical Preparations; Phenethylamines; Propranolol; Sewage; Sulfamethoxazole; Tamoxifen; Thioridazine; Water Pollutants, Chemical

2010