Page last updated: 2024-08-16

thioridazine and olanzapine

thioridazine has been researched along with olanzapine in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (8.11)	18.2507
2000's	28 (75.68)	29.6817
2010's	6 (16.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A	1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L	1
Topliss, JG; Yoshida, F	1
Grinde, E; Herrick-Davis, K; Teitler, M	1
Chen, XL; Kang, J; Kongsamut, S; Rampe, D; Roehr, J	1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S	1
Keserü, GM	1
Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Jia, L; Sun, H	1
Ahman, M; Holmén, AG; Wan, H	1
Giordanetto, F; Leach, AG; Zachariae, U	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Sen, S; Sinha, N	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Marr, I; Schlicker, E	1
Hägg, S; Lindqvist, L; Mjörndal, T	1
Dai, J; Fowler, WL; Ichikawa, J; Meltzer, HY; O'Laughlin, IA	1
Philibin, SD; Porter, JH; Vann, RE; Varvel, SA; Wise, LE	1
Nomikos, GG; Rodriguez, DE; Shirazi-Southall, S	1
Campbell, C; King, DJ; Silke, B	1
Gupta, S	1
Lin, DA; Zareba, W	1
Alevizos, B	1
Anziano, R; Cutler, NR; Harrigan, EP; Miceli, JJ; Middle, M; Reeves, KR; Shiovitz, T; Sramek, J; Watsky, E	1
Curtis, LH; Dans, PE; Hutchison, S; Krishnan, RR; Masselink, LE; Schulman, KA; Wright, A; Østbye, T	1
Barbui, C; Fortino, I; Percudani, M; Petrovich, L	1
Beasley, CM; Carlson, C; Crumb, WJ; Ekins, S; Sarazan, RD; Wikel, JH; Wrighton, SA	1
Iwata, S; Miyata, A; Morioka, H	1
Gutierrez, AM; Mohammadi, M; Weber, M	1
Flanagan, RJ; Handley, S; Patel, MX	1
Bonarek, P; Chmielińska, A; Dziedzicka-Wasylewska, M; Polit, A; Skrobecki, P; Stepien, P; Wisniewska-Becker, A	1

Reviews

4 review(s) available for thioridazine and olanzapine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Safety in treating bipolar disorder. The Journal of family practice, 2003, Volume: Suppl Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Dyskinesias; Haloperidol; Humans; Hyperglycemia; Hyperprolactinemia; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Thioridazine; Weight Gain	2003
Antipsychotic drugs and QT interval prolongation. The Psychiatric quarterly, 2003,Fall, Volume: 74, Issue:3 Topics: Age Factors; Algorithms; Antipsychotic Agents; Benzodiazepines; Death, Sudden, Cardiac; Dopamine Antagonists; Drug Labeling; Haloperidol; Humans; Long QT Syndrome; Olanzapine; Pirenzepine; Sex Factors; Thioridazine; Torsades de Pointes	2003
Antipsychotic-related fatal poisoning, England and Wales, 1993-2013: impact of the withdrawal of thioridazine. Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:6 Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Drug Recalls; England; Heroin; Humans; Methadone; Morphine; Olanzapine; Poisoning; Quetiapine Fumarate; Thioridazine; Wales	2016

Trials

2 trial(s) available for thioridazine and olanzapine

Article	Year
The potential cardiotoxicity of antipsychotic drugs as assessed by heart rate variability. Journal of psychopharmacology (Oxford, England), 2002, Volume: 16, Issue:4 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Conscious Sedation; Double-Blind Method; Heart Diseases; Heart Rate; Humans; Male; Neuropsychological Tests; Olanzapine; Pirenzepine; Predictive Value of Tests; Psychomotor Performance; Reaction Time; Risk Assessment; Risperidone; Thioridazine	2002
A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition. Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:1 Topics: Adolescent; Adult; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Biotransformation; Clozapine; Dibenzothiazepines; Electrocardiography; Female; Haloperidol; Heart Conduction System; Humans; Long QT Syndrome; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Risperidone; Thioridazine	2004

Article

Year

The potential cardiotoxicity of antipsychotic drugs as assessed by heart rate variability.

Journal of psychopharmacology (Oxford, England), 2002, Volume: 16, Issue:4

Topics: Adult; Antipsychotic Agents; Benzodiazepines; Conscious Sedation; Double-Blind Method; Heart Diseases; Heart Rate; Humans; Male; Neuropsychological Tests; Olanzapine; Pirenzepine; Predictive Value of Tests; Psychomotor Performance; Reaction Time; Risk Assessment; Risperidone; Thioridazine

2002

A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition.

Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:1

Topics: Adolescent; Adult; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Biotransformation; Clozapine; Dibenzothiazepines; Electrocardiography; Female; Haloperidol; Heart Conduction System; Humans; Long QT Syndrome; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Risperidone; Thioridazine

2004

Other Studies

31 other study(ies) available for thioridazine and olanzapine

Article	Year
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3 Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin	1994
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes	1998
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1 Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists	2000
A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs. European journal of pharmacology, 2002, Aug-16, Volume: 450, Issue:1 Topics: Animals; Antipsychotic Agents; Cation Transport Proteins; Cell Line; Clinical Trials as Topic; Cricetinae; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Trans-Activators; Transcriptional Regulator ERG	2002
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3 Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain	2003
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs. Psychopharmacology, 2005, Volume: 179, Issue:2 Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection	2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers. Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14 Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
The moderate affinity of clozapine at H3 receptors is not shared by its two major metabolites and by structurally related and unrelated atypical neuroleptics. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Binding, Competitive; Clozapine; Dibenzothiepins; Dose-Response Relationship, Drug; Histamine Antagonists; Isotope Labeling; Male; Methylhistamines; Mice; Olanzapine; Pirenzepine; Rats; Rats, Wistar; Receptors, Histamine H3; Remoxipride; Risperidone; Structure-Activity Relationship; Thioridazine; Tritium	1996
Repeated episodes of hypothermia in a subject treated with haloperidol, levomepromazine, olanzapine, and thioridazine. Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:1 Topics: Aged; Antipsychotic Agents; Benzodiazepines; Female; Haloperidol; Humans; Hypothermia; Methotrimeprazine; Olanzapine; Pirenzepine; Thioridazine	2001
Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:3 Topics: Acetylcholine; Acetylcholinesterase; Animals; Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Cholinesterase Inhibitors; Clozapine; Corpus Striatum; Haloperidol; Male; Nucleus Accumbens; Olanzapine; Oxotremorine; Piperazines; Pirenzepine; Rats; Rats, Sprague-Dawley; Risperidone; Scopolamine; Sulpiride; Thiazoles; Thioridazine	2002
Effects of antipsychotic drugs on operant responding after acute and repeated administration. Psychopharmacology, 2002, Volume: 160, Issue:2 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Conditioning, Operant; Dibenzothiazepines; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Indoles; Male; Olanzapine; Pirenzepine; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Thioridazine; Time Factors	2002
Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:5 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Dialysis Solutions; Dopamine Antagonists; Extracellular Space; Haloperidol; Hippocampus; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Microdialysis; Olanzapine; Piperazines; Pirenzepine; Rats; Rats, Wistar; Risperidone; Serotonin Antagonists; Thiazoles; Thioridazine	2002
Adverse drug reaction update. Adverse drug reactions and toxicological reviews, 2002, Volume: 21, Issue:4 Topics: Adult; Adverse Drug Reaction Reporting Systems; Benzodiazepines; Bupropion; Carbolines; Child; Epirubicin; Europe; Humans; Olanzapine; Pirenzepine; Pyrones; Thioridazine; Vigabatrin	2002
Dependence and chronic psychosis with D-nor-pseudoephedrine. European psychiatry : the journal of the Association of European Psychiatrists, 2003, Volume: 18, Issue:8 Topics: Antipsychotic Agents; Appetite; Appetite Depressants; Benzodiazepines; Central Nervous System Stimulants; Delusions; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ephedrine; Euphoria; Female; Hallucinations; Haloperidol; Humans; Long-Term Care; Mazindol; Middle Aged; Olanzapine; Psychoses, Substance-Induced; Recurrence; Substance Withdrawal Syndrome; Substance-Related Disorders; Thioridazine	2003
Atypical antipsychotic drugs and diabetes mellitus in a large outpatient population: a retrospective cohort study. Pharmacoepidemiology and drug safety, 2005, Volume: 14, Issue:6 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Clozapine; Cohort Studies; Databases, Factual; Diabetes Mellitus; Dibenzothiazepines; Drug Prescriptions; Female; Humans; Incidence; Insurance Claim Reporting; Male; Middle Aged; Multivariate Analysis; Olanzapine; Outpatients; Piperazines; Quetiapine Fumarate; Retrospective Studies; Risperidone; Sex Factors; Thiazoles; Thioridazine; Time Factors; United States	2005
Antipsychotic drug prescribing in the elderly is cause for concern. International clinical psychopharmacology, 2004, Volume: 19, Issue:6 Topics: Aged; Antipsychotic Agents; Benzodiazepines; Data Collection; Drug Prescriptions; Drug Utilization; Female; Humans; Italy; Male; Olanzapine; Psychotic Disorders; Risperidone; Thioridazine	2004
Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis. Pharmaceutical research, 2006, Volume: 23, Issue:6 Topics: Action Potentials; Aged; Antipsychotic Agents; Benzodiazepines; Cell Line; Electrocardiography; Ether-A-Go-Go Potassium Channels; Humans; Imidazoles; In Vitro Techniques; Indoles; Ion Channels; Middle Aged; Molecular Structure; Myocytes, Cardiac; Neural Networks, Computer; Olanzapine; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Sodium Channels; Structure-Activity Relationship; Thioridazine; Transfection	2006
Classification of antipsychotic drugs by gene expression in the frontal cortex of mice. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2006, Volume: 26, Issue:2 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cluster Analysis; Dibenzothiazepines; Frontal Lobe; Gene Expression; Male; Mice; Olanzapine; Quetiapine Fumarate; Thioridazine	2006
The risks and benefits of switching antipsychotics: a case study approach. Perspectives in psychiatric care, 2009, Volume: 45, Issue:1 Topics: Antipsychotic Agents; Benzodiazepines; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypercholesterolemia; Hypertriglyceridemia; Long-Term Care; Male; Middle Aged; Olanzapine; Paroxetine; Psychotic Disorders; Risk Assessment; Schizophrenia; Thioridazine	2009
Sulpiride, Amisulpride, Thioridazine, and Olanzapine: Interaction with Model Membranes. Thermodynamic and Structural Aspects. ACS chemical neuroscience, 2017, 07-19, Volume: 8, Issue:7 Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Calorimetry; Dynamic Light Scattering; Electron Spin Resonance Spectroscopy; Membranes, Artificial; Models, Chemical; Molecular Structure; Olanzapine; Phosphatidylcholines; Phosphatidylglycerols; Protons; Sulpiride; Thermodynamics; Thioridazine; Water	2017