Page last updated: 2024-08-16

thioridazine and nortriptyline

thioridazine has been researched along with nortriptyline in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199022 (59.46)18.7374
1990's1 (2.70)18.2507
2000's7 (18.92)29.6817
2010's7 (18.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Modestin, J; Petrin, A1
Gabriel, E; Karobath, M; Lenz, G1
Lin, HL; Marks, MJ; Medzihradsky, F1
Davidson, S; Elizur, A; Steiner, M1
Henry, BW; Overall, JE; Woodward, JA1
Frisk-Holmberg, M; van der Kleijn, E1
Taub, A1
De Leenheer, A; Heyndrickx, A1
Fuller, RW; Slater, IH; Snoddy, HD1
Zingales, I1
Tuck, JR1
Grivell, PD; Pritchard, DW; Rump, EE1
Vencovský, E1
Furlong, FW; Luby, ED1
Bechthold, HG; Schottky, A1
Núnek, K1
Milner, G1
Schechter, MD1
Arzu, D; DeJohn, C; Korivi, P; Leelavathi, DE; Misra, CH; Schoolar, J; Smith, RC; Vroulis, G1
Cesková, E; Náhunek, K; Novotná, H; Rysánek, R; Svestka, J1
Ghaemi, SN; Kirkwood, CK1
LEAHY, MR; ROSE, JT1
Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA1
Haefeli, WE; Kopitz, J; Mayer, T; Plaschke, K; Seidling, HM; Weiss, J1

Reviews

2 review(s) available for thioridazine and nortriptyline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants].
    International journal of clinical pharmacology and biopharmacy, 1976, Volume: 13, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Fluphenazine; Humans; Imipramine; Nortriptyline; Perazine; Phenelzine; Thioridazine

1976

Trials

2 trial(s) available for thioridazine and nortriptyline

ArticleYear
[Treatment of depressive conditions with nortriptyline].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1966, Volume: 18, Issue:1

    Topics: Aged; Anxiety; Arteriosclerosis; Clinical Trials as Topic; Depression; Humans; Nortriptyline; Thioridazine

1966
Lithium in the control of mania.
    International journal of neuropsychiatry, 1967, Volume: 3, Issue:4

    Topics: Adult; Amitriptyline; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Nortriptyline; Thioridazine; Tranylcypromine; Trifluoperazine

1967

Other Studies

33 other study(ies) available for thioridazine and nortriptyline

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
[The extrapyramidal symptoms in the combination of lithium long-term lithium therapy with nortriptyline. A case report on the formation of a pathogenesis hypothesis].
    Der Nervenarzt, 1976, Volume: 47, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Bipolar Disorder; Chlorprothixene; Clopenthixol; Dibenzazepines; Drug Synergism; Drug Therapy, Combination; Female; Humans; Lithium; Long-Term Care; Nortriptyline; Parkinson Disease; Parkinson Disease, Secondary; Procyclidine; Propranolol; Synapses; Thioridazine

1976
Drug inhibitable ecta-ATPase in leukocytes.
    Life sciences, 1975, May-01, Volume: 16, Issue:9

    Topics: Adenosine Triphosphatases; Animals; Calcium; Cations, Divalent; Cations, Monovalent; Desipramine; Dinitrophenols; Enzyme Inhibitors; Kinetics; Leukocytes; Male; Nortriptyline; Oligomycins; Ouabain; Potassium; Rats; Sodium; Sulfhydryl Reagents; Thioridazine; Trifluoperazine

1975
A psychosomatic triad in a bipolar patient.
    The Journal of nervous and mental disease, 1977, Volume: 164, Issue:5

    Topics: Asthma; Bipolar Disorder; Dermatitis, Seborrheic; Drug Therapy, Combination; Humans; Male; Middle Aged; Mother-Child Relations; Nortriptyline; Oral Stage; Peptic Ulcer; Psychophysiologic Disorders; Psychotherapy; Thioridazine

1977
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
    Diseases of the nervous system, 1975, Volume: 36, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine

1975
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
    European journal of pharmacology, 1972, Volume: 18, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine

1972
Relief of postherpetic neuralgia with psychotropic drugs.
    Journal of neurosurgery, 1973, Volume: 39, Issue:2

    Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents; Antipsychotic Agents; Female; Fluphenazine; Herpesviridae Infections; Humans; Male; Middle Aged; Neuralgia; Nortriptyline; Pain; Perphenazine; Thioridazine

1973
Identification of phenothiazine derivatives and analogs by x-ray diffraction. II. Active substances in pharmaceutical formulations.
    Journal - Association of Official Analytical Chemists, 1971, Volume: 54, Issue:3

    Topics: Amitriptyline; Chlorprothixene; Crystallization; Dibenzazepines; Fluphenazine; Imipramine; Methods; Methotrimeprazine; Nortriptyline; Opipramol; Perphenazine; Phenothiazines; Picrates; Prochlorperazine; Promazine; Promethazine; Quaternary Ammonium Compounds; Thioridazine; Triflupromazine; X-Ray Diffraction

1971
Metabolic interactions between nortriptyline and thioridazine in rats.
    Toxicology and applied pharmacology, 1974, Volume: 29, Issue:2

    Topics: Animals; Drug Interactions; Male; Nortriptyline; Rats; Rats, Inbred Strains; Thioridazine

1974
Systematic identification of psychotropic drugs by thin layer chromatography. II.
    Journal of chromatography, 1968, Mar-26, Volume: 34, Issue:1

    Topics: Amitriptyline; Chlorpromazine; Chlorprothixene; Chromatography, Thin Layer; Desipramine; Female; Humans; Imipramine; Male; Meprobamate; Nortriptyline; Phenothiazines; Schizophrenia; Silicon Dioxide; Thioridazine; Tranquilizing Agents

1968
Effects of chlorpromazine, thioridazine and haloperidol on adrenergic transmitter mechanisms in man.
    European journal of clinical pharmacology, 1973, Volume: 6, Issue:2

    Topics: Animals; Biological Transport, Active; Blood Pressure; Cell Membrane; Chlorpromazine; Drug Interactions; Haloperidol; Humans; In Vitro Techniques; Iris; Norepinephrine; Nortriptyline; Phentolamine; Rats; Receptors, Adrenergic; Sympathetic Nervous System; Synaptic Transmission; Thioridazine; Tritium; Tyramine

1973
Time series for symptom-clusters in a case of manic-depressive illness.
    The Australian and New Zealand journal of psychiatry, 1972, Volume: 6, Issue:4

    Topics: Benztropine; Bipolar Disorder; Electroconvulsive Therapy; Female; Humans; Lithium; Middle Aged; Nortriptyline; Phenelzine; Psychological Tests; Thioridazine; Time Factors

1972
[Phasic depression and epilepsy. Two polar cases].
    Der Nervenarzt, 1971, Volume: 42, Issue:10

    Topics: Adult; Bipolar Disorder; Chlorprothixene; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Haloperidol; Humans; Imidazoles; Middle Aged; Nortriptyline; Phenothiazines; Piperazines; Primidone; Thioridazine

1971
[Current problems of endogenous depression].
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; Fluphenazine; Humans; Imipramine; Methotrimeprazine; Nortriptyline; Perphenazine; Thioridazine

1970
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
    British journal of pharmacology, 1968, Volume: 34, Issue:2

    Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine; Diazepam; Dibenzazepines; Drug Synergism; Ethanol; Humans; Imipramine; Methylphenidate; Mice; Nortriptyline; Phenelzine; Phenobarbital; Reflex; Substance-Related Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine

1968
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imipramine; Male; Nortriptyline; Promethazine; Rats; Sodium Chloride; Thioridazine; Trifluoperazine

1980
Receptor techniques in the study of plasma levels of neuroleptics and antidepressant drugs.
    Communications in psychopharmacology, 1980, Volume: 4, Issue:6

    Topics: Chromatography, Gas; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Haloperidol; Humans; Mood Disorders; Nortriptyline; Radioligand Assay; Schizophrenia; Thioridazine

1980
[Comparison of the effectiveness of tranylcypromine, nortriptyline, thioridazine and amitriptyline in two syndromological types of endogenous depression (author's transl)].
    Ceskoslovenska psychiatrie, 1981, Volume: 77, Issue:4

    Topics: Adult; Amitriptyline; Depressive Disorder; Female; Humans; Male; Middle Aged; Nortriptyline; Thioridazine; Tranylcypromine

1981
Elevation of nortriptyline plasma levels after cotreatment with paroxetine and thioridazine.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Male; Nortriptyline; Paroxetine; Psychiatric Status Rating Scales; Thioridazine

1998
A PRELIMINARY STUDY OF NORTRIPTYLINE IN DEPRESSION.
    The American journal of psychiatry, 1964, Volume: 121

    Topics: Antidepressive Agents; Biomedical Research; Depression; Depressive Disorder; Nortriptyline; Thioridazine; Toxicology

1964
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol

2007
Limitations of the Anticholinergic Activity Assay and Assay-Based Anticholinergic Drug Scales.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2016, Volume: 24, Issue:12

    Topics: Amitriptyline; Cholinergic Antagonists; Cognitive Dysfunction; Diphenhydramine; Dose-Response Relationship, Drug; Drug Interactions; Furosemide; Humans; Nortriptyline; Pilocarpine; Radioligand Assay; Thioridazine

2016