Page last updated: 2024-08-16

thioridazine and diazepam

thioridazine has been researched along with diazepam in 91 studies

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-199068 (74.73)18.7374
1990's3 (3.30)18.2507
2000's10 (10.99)29.6817
2010's10 (10.99)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allen, RC; Bauer, VJ; Cornfeldt, ML; Fielding, S; Geyer, HM; Kosley, RW; McFadden, AR; Shutske, GM; Wilker, JC1
Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Andrews, PR; Craik, DJ; Martin, JL1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Abraham, MH; Acree, WE; Ibrahim, A1
Ahman, M; Holmén, AG; Wan, H1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Adler, MW; Baldino, F; Cowan, A; Geller, EB1
Glaeser, BS; Hare, TA; Oleweiler, DB; Vogel, WH1
Kissin, B1
Beaubien, AR; Coldwell, BB; Mathieu, LF1
Kurland, ML1
Linnoila, M; Mattila, MJ; Saario, I1
Covington, JS1
Henry, BW; Overall, JE; Woodward, JA1
Snodgrass, RE1
Gogerty, JH; Iorio, LC; Ryan, EA1
Fillmore, MT; Ruggles, JL; Taukulis, HK1
McDaniel, KD1
Alimova, RA; Tibilova, AU1
Beckers, W1
Keegan, DL; Rajput, AH1
Marcy, R; Quermonne, MA1
McNair, DM1
Gouret, C; Raynaud, G1
Dixon, K; Taeschler, M2
Bowden, CL; Rosenthal, SH1
Denber, HC; Goldner, F; Seeman, MV1
Nardini, L1
Oge, V1
Linnoila, M; Mäki, M1
Masland, RL; Pippenger, CE; Siris, JH; Werner, WL1
Greene, NM1
Kirven, LE; Montero, EF1
Linnoila, M1
Anttila, M; Linnoila, M; Otterström, S1
Clark, EL; Gordon, PE; Jenkins, BW; Rickels, K; Rose, CK; Rosenfeld, H; Weise, CC1
Kellner, R; Schuster, TS; Winslow, WW1
Grützner, A1
Soyka, D1
Hofmann, KW; Manach, J; Sögtrop, HH1
Fracchia, J; Merlis, S; Sheppard, C1
Howell, MC; Rever, GW; Rutledge, A; Scholl, ML; Trowbridge, F1
Harinath, M; Hussain, MZ; Murphy, J1
Glick, BS; Schulman, D; Turecki, S1
Garriott, JC; Stolman, A1
Muller, DJ1
Perez de Francisco, C1
Nuutila, A; Viukari, M1
Arnold, OH; Heves, HP1
Vaglum, P1
Schaumann, W; Wohlfarth-Ribbentrop, A1
Milner, G2
Perlson, P; Tobin, JM1
McLaughlin, BE1
Senault, B1
Fletcher, BD; Lussier-Lazaroff, J1
Gauron, EF; Rowley, VN1
Langner, E1
Cramond, WA1
Sofia, RD1
Cohen, MM; Frosch, WA; Hirschhorn, K1
Dordain, G; Goulon, M; Lévy-Alcover, MA; Nouailhat, F1
Overall, JE; Rhoades, HM1
Beckmann, H; Emrich, HM; Gramsch, C; Haas, S; John, S; von Zerssen, D; Zaudig, M1
Stotsky, B1
Bigot, MC; Camsonne, R; Debruyne, D; Moulin, MA1
Bergqvist, Y; Breyer, S; Burgmann, H; Feistauer, S; Feucht, M; Graninger, W; Hellgren, U; Uhl, F; Winkler, S1
Dent, J1
GROSS, H; KALTENBAECK, E1
BORIS, A; STEVENSON, RH1
Demars, JP; Lofft, JG1
Chu, X; Ding, F; Ling, Y; Sun, L; Suo, R; Xu, C; Yang, M; Zhang, F1

Reviews

6 review(s) available for thioridazine and diazepam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1).
    Clinical pediatrics, 1986, Volume: 25, Issue:2

    Topics: Adolescent; Aggression; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Developmental Disabilities; Diazepam; Histamine H1 Antagonists; Humans; Imipramine; Lithium; Mental Disorders; Methylphenidate; Pemoline; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Thioridazine

1986
Self-evaluations of antidepressants.
    Psychopharmacologia, 1974, Volume: 37, Issue:4

    Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipramine; Dextroamphetamine; Diazepam; Doxepin; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methylphenidate; MMPI; Nialamide; Pargyline; Placebos; Psychiatric Status Rating Scales; Psychological Tests; Statistics as Topic; Thioridazine; Tranylcypromine

1974
Halothane anesthesia and hepatitis in a high-risk population.
    The New England journal of medicine, 1973, Aug-09, Volume: 289, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Diazepam; Enzyme Induction; Halothane; Humans; Liver; Microsomes, Liver; Phenobarbital; Phenytoin; Postoperative Complications; Reserpine; Thioridazine; Time Factors

1973
[Treatment of endogenous depression with psychopharmaceutics].
    Medizinische Klinik, 1967, Feb-17, Volume: 62, Issue:7

    Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Chlorprothixene; Depression; Diazepam; Humans; Imipramine; Methotrimeprazine; Thioridazine

1967
[Dipotassium chlorazepate. Clinical reports on a new anxiolytic].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:1

    Topics: Adult; Aged; Alcoholism; Automobile Driving; Cardiovascular Diseases; Diabetes Mellitus; Diazepam; Dibenzazepines; Drug Tolerance; Fear; Female; Gastrointestinal Diseases; Humans; Male; Mental Disorders; Meprobamate; Middle Aged; Neurotic Disorders; Placebos; Psychotic Disorders; Thioridazine; Thyroid Diseases; Tranquilizing Agents

1970

Trials

18 trial(s) available for thioridazine and diazepam

ArticleYear
Neurotic depression an empirical guide to two specific drug treatments.
    Diseases of the nervous system, 1976, Volume: 37, Issue:8

    Topics: Adjustment Disorders; Anxiety; Clinical Trials as Topic; Diazepam; Drug Evaluation; Humans; Hypochondriasis; Self-Assessment; Suicide Prevention; Thioridazine

1976
Modification by diazepam or thioridazine of the psychomotor skills related to driving: a subacute trial in neurotic out-patients.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:5

    Topics: Adult; Ambulatory Care; Anxiety Disorders; Attention; Automobile Driving; Diazepam; Female; Humans; Male; Motor Skills; Placebos; Reaction Time; Thioridazine; Visual Perception

1976
Alleviating agitation, apprehension, and related symptoms in geriatric patients: A double-blind comparison of a phenothiazine and a benzodiazepien.
    Southern medical journal, 1975, Volume: 68, Issue:6

    Topics: Aged; Anxiety; Clinical Trials as Topic; Dementia; Depression; Diazepam; Drug Evaluation; Female; Humans; Male; Nursing Homes; Psychiatric Status Rating Scales; Sleep Wake Disorders; Thioridazine

1975
Self-evaluations of antidepressants.
    Psychopharmacologia, 1974, Volume: 37, Issue:4

    Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipramine; Dextroamphetamine; Diazepam; Doxepin; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methylphenidate; MMPI; Nialamide; Pargyline; Placebos; Psychiatric Status Rating Scales; Psychological Tests; Statistics as Topic; Thioridazine; Tranylcypromine

1974
A double-blind comparison of thioridazine (Mellaril) versus diazepam (valium) in patients with chronic mixed anxiety and depressive symptoms.
    Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:5

    Topics: Adult; Anxiety; Clinical Trials as Topic; Depression; Diazepam; Humans; Middle Aged; Psychiatric Status Rating Scales; Thioridazine

1973
Acute effects of alcohol, diazepam, thioridazine, flupenthixole and atropine on psychomotor performance profiles.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:4

    Topics: Adult; Atropine; Attention; Auditory Perception; Diazepam; Drug Interactions; Ethanol; Female; Humans; Male; Motor Activity; Piperazines; Placebos; Reaction Time; Statistics as Topic; Thioridazine; Time Factors; Visual Perception; Xanthenes

1974
Comparison of thioridazine and diazepam in the control of nonpsychotic symptoms associated with senility: double-blind study.
    Journal of the American Geriatrics Society, 1973, Volume: 21, Issue:12

    Topics: Aged; Behavior; Clinical Trials as Topic; Diazepam; Electrocardiography; Female; Hospitalization; Humans; Length of Stay; Male; Mental Disorders; Psychiatric Status Rating Scales; Sleep Wake Disorders; Speech Disorders; Thioridazine; Time Factors

1973
Effects of diazepam, chlordiazepoxide, thioridazine, haloperidole, flupenthixole and alcohol on psychomotor skills related to driving.
    Annales medicinae experimentalis et biologiae Fenniae, 1973, Volume: 51, Issue:3

    Topics: Adult; Attention; Automobile Driving; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Drug Synergism; Ethanol; Haloperidol; Humans; Male; Motor Skills; Piperazines; Placebos; Reaction Time; Thioridazine; Time Factors

1973
Serum chlordiazepoxide, diazepam and thioridazine concentrations after the simultaneous ingestion of alcohol or placebo drink.
    Annals of clinical research, 1974, Volume: 6, Issue:1

    Topics: Chlordiazepoxide; Chromatography, Gas; Chromatography, Thin Layer; Clinical Trials as Topic; Diazepam; Drug Interactions; Ethanol; Humans; Male; Placebos; Stimulation, Chemical; Thioridazine; Time Factors

1974
Thiothixene and thioridazine in anxiety.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 125, Issue:0

    Topics: Antisocial Personality Disorder; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Sex Factors; Social Class; Thioridazine; Thiothixene

1974
A comparison of thioridazine and diazepam in non-psychotic anxiety-depression: a pilot study.
    Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:3

    Topics: Adjustment Disorders; Administration, Oral; Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Personality Inventory; Pilot Projects; Psychiatric Status Rating Scales; Thioridazine; Time Factors

1972
[The effect of psychopharmacological drugs and other central nervous system effecting drugs on experimental nystagmus].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1968, Volume: 36, Issue:9

    Topics: Amitriptyline; Apomorphine; Aporphines; Barbiturates; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Diazepam; Dimenhydrinate; Eye Movements; Fluphenazine; Haloperidol; Humans; Imipramine; Schizophrenia; Thioridazine; Triflupromazine

1968
Combination medications in psychiatric treatment: patterns in a group of elderly hospital patients.
    Journal of the American Geriatrics Society, 1971, Volume: 19, Issue:4

    Topics: Age Factors; Aged; Amitriptyline; Antidepressive Agents; Antihypertensive Agents; Antisocial Personality Disorder; Bipolar Disorder; Chlorpromazine; Chlorprothixene; Clinical Trials as Topic; Depressive Disorder, Major; Diazepam; Drug Synergism; Female; Geriatrics; Humans; Imipramine; Male; Mental Disorders; Middle Aged; Perphenazine; Psychoses, Alcoholic; Reserpine; Schizophrenia; Sex Factors; Thioridazine; Tranquilizing Agents; Trifluoperazine

1971
[Necessity of hypnotics for seriously ill chronic psychiatric patients].
    Duodecim; laaketieteellinen aikakauskirja, 1966, Volume: 82, Issue:14

    Topics: Clinical Trials as Topic; Diazepam; Humans; Psychotic Disorders; Thioridazine

1966
[The treatment of endogenous depression with monochlorimipramin].
    Wiener klinische Wochenschrift, 1967, Jan-06, Volume: 79, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Chlordiazepoxide; Clinical Trials as Topic; Depression; Diazepam; Humans; Imipramine; Thioridazine

1967
The significance of treatment effects across several independent studies.
    Journal of psychiatric research, 1981, Volume: 16, Issue:4

    Topics: Antipsychotic Agents; Anxiety Disorders; Arousal; Clinical Trials as Topic; Diazepam; Dihydroergotoxine; Double-Blind Method; Drug Therapy, Combination; Humans; Mental Disorders; Outcome and Process Assessment, Health Care; Psychiatric Status Rating Scales; Psychotropic Drugs; Schizophrenia; Statistics as Topic; Thioridazine

1981
Multicenter study comparing thioridazine with diazepam and placebo in elderly, nonpsychotic patients with emotional and behavioral disorders.
    Clinical therapeutics, 1984, Volume: 6, Issue:4

    Topics: Affective Symptoms; Aged; Clinical Trials as Topic; Dementia; Diazepam; Double-Blind Method; Humans; Psychiatric Status Rating Scales; Thioridazine

1984
A chemotherapeutic alternative to the antianxiety agents for the extended treatment of psychoneurosis.
    Diseases of the nervous system, 1974, Volume: 35, Issue:9

    Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neurotic Disorders; Psychiatric Status Rating Scales; Thioridazine; Treatment Outcome

1974

Other Studies

68 other study(ies) available for thioridazine and diazepam

ArticleYear
Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 4. Central nervous system depressants.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:11

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Central Nervous System Depressants; Dogs; Dose-Response Relationship, Drug; Escape Reaction; Female; Haplorhini; Humans; Male; Rats; Receptors, Dopamine; Saimiri; Spiro Compounds; Stereotyped Behavior; Structure-Activity Relationship; Vomiting

1978
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:5

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship

1989
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Effects of antipsychotic and antianxiety drugs on the morphine abstinence syndrome in rats.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Body Weight; Chlordiazepoxide; Chlorpromazine; Diazepam; Haloperidol; Humans; Male; Morphine Dependence; Rats; Substance Withdrawal Syndrome; Thioridazine

1979
GABA levels in cerebrospinal fluid of patients with Huntington's chorea: a preliminary report.
    Biochemical medicine, 1975, Volume: 12, Issue:4

    Topics: Adult; Aged; Aminobutyrates; Amitriptyline; Chlorpromazine; Diazepam; Female; gamma-Aminobutyric Acid; Haloperidol; Humans; Huntington Disease; Imipramine; Male; Middle Aged; Thioridazine; Time Factors

1975
The use of psychoactive drugs in the long-term treatment of chronic alcoholics.
    Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252

    Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Chronic Disease; Depression; Diazepam; Disulfiram; Drug Synergism; Drug Therapy, Combination; Humans; Imipramine; Mental Disorders; New York City; Patient Acceptance of Health Care; Psychotherapy; Substance Withdrawal Syndrome; Substance-Related Disorders; Thioridazine

1975
Effects of thioridazine and diazepam on the pharmacokinetics of [14C]imipramine in rat: acute study.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:7

    Topics: Animals; Bile; Diazepam; Gastric Mucosa; Imipramine; Intestinal Absorption; Kinetics; Liver; Male; Rats; Thioridazine

1975
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
    Diseases of the nervous system, 1975, Volume: 36, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine

1975
Practical clinical psychopharmacology: the tranquilizers.
    The Journal of the Indiana State Medical Association, 1975, Volume: 68, Issue:10

    Topics: Butyrophenones; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Diazepam; Humans; Male; Meprobamate; Psychotic Disorders; Secologanin Tryptamine Alkaloids; Thioridazine; Thioxanthenes; Tranquilizing Agents; Trifluoperazine

1975
Combinations of selected CNS depressants with d-amphetamine or mazindol on food intake and motor activity of rats.
    European journal of pharmacology, 1976, Volume: 36, Issue:1

    Topics: Amobarbital; Animals; Dextroamphetamine; Diazepam; Drug Synergism; Eating; Indoles; Male; Mazindol; Motor Activity; Prochlorperazine; Rats; Thioridazine

1976
Neuroleptic-induced changes in the anxiolytic and myorelaxant properties of diazepam in the rat.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Chlorpromazine; Diazepam; Drug Interactions; Haloperidol; Male; Muscle Relaxants, Central; Pimozide; Rats; Thioridazine

1992
[Problem of transient dementias of old age (clinico-diagnostic aspect)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985, Volume: 85, Issue:9

    Topics: Aged; Amphetamine; Anxiety; Central Nervous System Stimulants; Dementia; Depressive Disorder; Diagnosis, Differential; Diazepam; Factitious Disorders; Humans; Psychotropic Drugs; Substance-Related Disorders; Thioridazine

1985
[Gilles de la Tourette's disease based on five own observations].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1973, May-30, Volume: 217, Issue:2

    Topics: Adolescent; Adult; Basal Ganglia Diseases; Compulsive Behavior; Diazepam; Dibenzocycloheptenes; Echolalia; Female; Haloperidol; Humans; Male; Methylamines; Perphenazine; Phenothiazines; Psychosurgery; Speech Disorders; Stereotaxic Techniques; Thiazines; Thioridazine; Tic Disorders; Tourette Syndrome

1973
Drug induced dystonia tarda: treatment with L-dopa.
    Diseases of the nervous system, 1973, Volume: 34, Issue:3

    Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Diazepam; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Evaluation Studies as Topic; Female; Humans; Middle Aged; Schizophrenia; Thioridazine; Trifluoperazine

1973
An improved method for studying the psychogalvanic reaction in mice and its inhibition by psycholeptic drugs. Comparison with the effects of other pharmacological agents.
    Psychopharmacologia, 1974, Feb-06, Volume: 34, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Benactyzine; Chlordiazepoxide; Chlorpromazine; Diazepam; Female; Galvanic Skin Response; Haloperidol; Hydroxyzine; Hypnotics and Sedatives; Male; Meprobamate; Methaqualone; Methotrimeprazine; Mice; Muscle Relaxants, Central; Neuromuscular Nondepolarizing Agents; Nitrazepam; Parasympatholytics; Pentobarbital; Phenobarbital; Phenothiazines; Thioridazine; Tranquilizing Agents; Trifluperidol

1974
[Activity of various neuroleptics after single repeated treatment in the mice submitted to the four plate test and the escape test].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1974, Volume: 168, Issue:2-3

    Topics: Animals; Chlorpromazine; Chlorprothixene; Diazepam; Drug Evaluation, Preclinical; Electroshock; Escape Reaction; Fluphenazine; Haloperidol; Methotrimeprazine; Mice; Perphenazine; Phenothiazines; Prochlorperazine; Thioridazine; Tranquilizing Agents; Trifluperidol

1974
Pharmacological differentiation of sedative drugs.
    Electroencephalography and clinical neurophysiology, 1969, Volume: 27, Issue:1

    Topics: Animals; Behavior, Animal; Diazepam; Mice; Phenobarbital; Promethazine; Rats; Thioridazine

1969
Paradoxical effects of phenothiazines.
    The Psychiatric quarterly, 1968, Volume: 42, Issue:1

    Topics: Adult; Amitriptyline; Chlorpromazine; Diazepam; Female; Humans; Meclofenoxate; Meprobamate; Phenothiazines; Prochlorperazine; Procyclidine; Schizophrenia; Thioridazine; Trifluoperazine; Trihexyphenidyl

1968
[Clinico-therapeutic evaluation of some psychopharmacologic drugs used in acute dissociative and anxiety syndromes in hospital practical experience].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1967, Oct-31, Volume: 91, Issue:5

    Topics: Acute Disease; Adult; Anxiety; Butanones; Chlorprothixene; Clopenthixol; Diazepam; Dissociative Disorders; Female; Humans; Male; Mental Disorders; Phenothiazines; Piperazines; Thioridazine; Tranquilizing Agents

1967
Drug therapy in alcoholism. It is especially important in the prevention of such complications as seizures, DT's, Wernicke's encephalopathy, or polyneuritis.
    IMJ. Illinois medical journal, 1971, Volume: 139, Issue:6

    Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Diazepam; Disulfiram; Humans; Hydroxyzine; Lysergic Acid Diethylamide; Magnesium; Polyneuropathies; Promazine; Psychoses, Alcoholic; Substance Withdrawal Syndrome; Thioridazine; Tranquilizing Agents; Vitamins; Wernicke Encephalopathy

1971
Anticonvulsant drug-serum levels in psychiatric patients with seizure disorders. Effects of certain psychotropic drugs.
    New York state journal of medicine, 1974, Volume: 74, Issue:9

    Topics: Chlorpromazine; Chromatography, Gas; Diazepam; Drug Interactions; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Thioridazine

1974
Hyperactivity in children: types, diagosis, drug therapy, approaches to management.
    Clinical pediatrics, 1972, Volume: 11, Issue:1

    Topics: Amphetamine; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chronic; Child; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Environment; Family; Female; Humans; Hyperkinesis; Methylphenidate; Motor Skills; Phenytoin; Thioridazine

1972
Tranquillizer-induced galactorrhea.
    Canadian Medical Association journal, 1972, May-20, Volume: 106, Issue:10

    Topics: Adolescent; Amitriptyline; Chlorprothixene; Diazepam; Female; Haloperidol; Humans; Lactation Disorders; Perphenazine; Pregnancy; Thioridazine; Tranquilizing Agents; Trifluoperazine

1972
Diazepam (Valium) treatment in childhood sleep disorders. A preliminary investigation.
    Diseases of the nervous system, 1971, Volume: 32, Issue:8

    Topics: Child; Diazepam; Enuresis; Female; Humans; Imipramine; Male; Sleep Wake Disorders; Somnambulism; Thioridazine

1971
Detection of some psychotherapeutic drugs and their metabolites in urine.
    Clinical toxicology, 1971, Volume: 4, Issue:2

    Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine

1971
ECT in LSD psychosis. a report of three cases.
    The American journal of psychiatry, 1971, Volume: 128, Issue:3

    Topics: Chlordiazepoxide; Chlorpromazine; Diazepam; Electroconvulsive Therapy; Humans; Lysergic Acid Diethylamide; Psychoses, Substance-Induced; Psychotherapy; Substance-Related Disorders; Therapeutic Community; Thioridazine

1971
[Psychopharmacological treatment of anxiety].
    La Prensa medica mexicana, 1971, Volume: 36, Issue:9

    Topics: Adult; Amitriptyline; Anxiety; Benzazepines; Carbamates; Chlordiazepoxide; Diazepam; Dibenzazepines; Female; Humans; Ketones; Meprobamate; Methotrimeprazine; Nitro Compounds; Oxazepam; Piperidines; Thioridazine

1971
[Therapeutic utilization of the ego-control-weakening effect of benzodiazepines. New viewpoint on the mechanism of action and indications for use].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1969, Volume: 23, Issue:2

    Topics: Child; Child Behavior Disorders; Chlordiazepoxide; Diazepam; Ego; Humans; Male; Milieu Therapy; Psychotherapy; Thioridazine; Tranquilizing Agents

1969
[Pharmacologic differentiation of sedatives].
    Revue neurologique, 1969, Volume: 120, Issue:6

    Topics: Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Conditioning, Classical; Diazepam; Emotions; Escape Reaction; Hypnotics and Sedatives; Mice; Motor Activity; Phenobarbital; Promethazine; Rats; Thioridazine; Tranquilizing Agents

1969
[Animal experimental comparison of tranquilizing effect of doxepine with known psychopharmaceuticals].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:12

    Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Conditioning, Classical; Depression, Chemical; Diazepam; Dibenzoxepins; Drug Synergism; Electroshock; Exploratory Behavior; Fear; Female; Humans; Hypnotics and Sedatives; Male; Mice; Movement; Muscle Relaxants, Central; Opipramol; Pentylenetetrazole; Rats; Strychnine; Thioridazine; Tranquilizing Agents; Urethane

1969
Interaction between barbiturates, alcohol and some psychotropic drugs.
    The Medical journal of Australia, 1970, Jun-13, Volume: 1, Issue:24

    Topics: Adolescent; Adult; Alcoholic Intoxication; Amitriptyline; Animals; Antidepressive Agents; Automobile Driving; Barbiturates; Chlorpromazine; Diazepam; Drug Synergism; Humans; Imipramine; Methylphenidate; Mice; Psychomotor Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine

1970
Treatment of psychic masochism in schizophrenic patients.
    Diseases of the nervous system, 1970, Volume: 31

    Topics: Adolescent; Adult; Amitriptyline; Behavior Therapy; Chlordiazepoxide; Diazepam; Female; Haloperidol; Humans; Male; Masochism; Perphenazine; Psychological Tests; Psychotherapy; Schizophrenia; Thioridazine; Trifluoperazine

1970
Unexpected failure of a satisfactory anti-depressive drug routine to control hostile expression in psychiatric out-patients.
    Diseases of the nervous system, 1970, Volume: 31

    Topics: Adjustment Disorders; Ambulatory Care; Antidepressive Agents; Anxiety; Bipolar Disorder; Chlordiazepoxide; Desipramine; Diazepam; Hostility; Humans; Meprobamate; Psychological Tests; Thioridazine; Tranquilizing Agents

1970
[Intraspecific aggressive behavior induced by apomorphine in the rat].
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine

1970
Rickets and anticonvulsant therapy in children: a roentgenologic investigation.
    Journal of the Canadian Association of Radiologists, 1971, Volume: 22, Issue:2

    Topics: Adolescent; Anticonvulsants; Benzazepines; Child; Dextroamphetamine; Diazepam; Ethosuximide; Female; Hand; Humans; Knee; Male; Methylphenidate; Phenobarbital; Phenytoin; Primidone; Radiography; Rickets; Thioridazine; Time Factors

1971
Infantile shock traumatization and the mitigating effects of tranquilizing drugs.
    The Journal of genetic psychology, 1967, Volume: 111, Issue:2d Half

    Topics: Analysis of Variance; Animals; Avoidance Learning; Chlorpromazine; Conditioning, Psychological; Diazepam; Electroshock; Female; Hydroxyzine; Male; Meprobamate; Prochlorperazine; Rats; Stress, Physiological; Thioridazine; Tranquilizing Agents

1967
[Management of psychotic drive disorders].
    Wiener medizinische Wochenschrift (1946), 1968, Sep-07, Volume: 118, Issue:36

    Topics: Adult; Bipolar Disorder; Chlorprothixene; Diazepam; Drive; Female; Fluphenazine; Humans; Imipramine; Male; Middle Aged; Paranoid Disorders; Psychotic Disorders; Schizophrenia; Thioridazine; Tranylcypromine; Trifluoperazine

1968
Organic psychosis.
    British medical journal, 1968, Nov-23, Volume: 4, Issue:5629

    Topics: Acute Disease; Affective Symptoms; Bender-Gestalt Test; Chlordiazepoxide; Chlorpromazine; Chronic Disease; Cognition Disorders; Diazepam; Female; Humans; Male; Middle Aged; Neurocognitive Disorders; Psychiatric Nursing; Social Behavior Disorders; Thioridazine

1968
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
    British journal of pharmacology, 1968, Volume: 34, Issue:2

    Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine; Diazepam; Dibenzazepines; Drug Synergism; Ethanol; Humans; Imipramine; Methylphenidate; Mice; Nortriptyline; Phenelzine; Phenobarbital; Reflex; Substance-Related Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine

1968
Effects of centrally active drugs on four models of experimentally-induced aggregession in rodents.
    Life sciences, 1969, Jul-01, Volume: 8, Issue:13

    Topics: Acridines; Aggression; Animals; Antidepressive Agents; Azepines; Chlordiazepoxide; Desipramine; Diazepam; Electrocoagulation; Electroshock; Ethers, Cyclic; Humans; Imipramine; Mice; Models, Biological; Rats; Rotation; Social Isolation; Thioridazine; Tranquilizing Agents

1969
Cytogenetic effects of tranquilizing drugs in vivo and in vitro.
    JAMA, 1969, Mar-31, Volume: 207, Issue:13

    Topics: Adolescent; Adult; Child; Chlordiazepoxide; Chlorpromazine; Chromosome Aberrations; Culture Techniques; Diazepam; Female; Fluphenazine; Humans; Leukocytes; Male; Middle Aged; Thioridazine; Time Factors; Tranquilizing Agents

1969
[Toxic coma with autonomic sideration, with a favorable outcome].
    Revue neurologique, 1967, Volume: 116, Issue:4

    Topics: Adult; Amobarbital; Body Temperature; Brain; Cardiovascular System; Chlorpromazine; Coma; Diazepam; Dysautonomia, Familial; Electroencephalography; Female; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Methotrimeprazine; Middle Aged; Neurologic Manifestations; Phenelzine; Phenobarbital; Poisoning; Respiratory System; Secobarbital; Thioridazine; Tranquilizing Agents

1967
The effect of neuroleptic treatment and of high dosage diazepam therapy on beta-endorphin immunoreactivity in plasma of schizophrenic patients.
    Journal of neural transmission, 1984, Volume: 59, Issue:2

    Topics: Adolescent; Adult; Antipsychotic Agents; beta-Endorphin; Diazepam; Dose-Response Relationship, Drug; Endorphins; Female; Fluspirilene; Haloperidol; Humans; Male; Schizophrenia; Thioridazine

1984
Wall-coated open tubular column coupled with nitrogen-selective detector for routine GLC determination of diazepam, meprobamate, phenylbutazone, and thioridazine in serum.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:7

    Topics: Adolescent; Adult; Child; Chromatography, Gas; Diazepam; Epilepsy; Female; Humans; Male; Meprobamate; Middle Aged; Nitrogen; Phenylbutazone; Thioridazine

1980
[Mefloquine and sulfadoxine/pyrimethamine overdose in malaria tropica].
    Wiener klinische Wochenschrift, 1993, Volume: 105, Issue:2

    Topics: Adult; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Haloperidol; Humans; Malaria, Falciparum; Male; Mefloquine; Psychoses, Substance-Induced; Pyrimethamine; Sulfadoxine; Thioridazine

1993
Catatonic syndrome following recovery from neuroleptic malignant syndrome.
    Journal of intellectual disability research : JIDR, 1995, Volume: 39 ( Pt 5)

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Catatonia; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Humans; Intellectual Disability; Male; Middle Aged; Neuroleptic Malignant Syndrome; Psychomotor Agitation; Sleep Initiation and Maintenance Disorders; Syndrome; Thioridazine

1995
[THE ADVANCES OF MODERN PHARMACOTHERAPY OF THE ENDOGENOUS PSYCHOSES AND ITS SIGNIFICANCE FOR INSTITUTIONAL PSYCHIATRY].
    Wiener Zeitschrift fur Nervenheilkunde und deren Grenzgebiete, 1963, Volume: 21

    Topics: Chlordiazepoxide; Chlorprothixene; Diazepam; Humans; Phenothiazines; Psychiatry; Psychotic Disorders; Schizophrenia; Thioridazine; Tranquilizing Agents

1963
EFFECTS OF SOME PSYCHOTROPIC DRUGS UPON URINARY WATER OUTPUT.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Diazepam; Diuresis; Imipramine; Pharmacology; Psychotropic Drugs; Rats; Research; Thioridazine; Tranquilizing Agents; Urine; Water

1964
[Simultaneous determination of 10 unapproved sedative drugs in feeds by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry].
    Se pu = Chinese journal of chromatography, 2012, Volume: 30, Issue:5

    Topics: Animal Feed; Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Diazepam; Hypnotics and Sedatives; Mass Spectrometry; Nitrazepam; Pyridines; Thioridazine; Zolpidem

2012