Page last updated: 2024-08-16

thioridazine and clomipramine

thioridazine has been researched along with clomipramine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19906 (24.00)18.7374
1990's0 (0.00)18.2507
2000's9 (36.00)29.6817
2010's8 (32.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Abraham, MH; Acree, WE; Ibrahim, A1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dexheimer, TS; Jones, CL; Njomen, E; Sjögren, B; Tepe, JJ1
Fry, EE; Ren, J; Stuart, DI; Townsend, AR; Xiao, J; Zhao, Y1
Alonso, C; Campillo, NE; Cuesta-Geijo, MÁ; Delgado, R; Gil, C; Ginex, T; Morales-Tenorio, M; Muñoz-Fontela, C1
Chen, W; Han, S; Hu, Y; Li, H; Tong, X; Yang, L; Zuo, J1
Ahlenius, S; Heimann, M; Larsson, K1
Lüllmann-Rauch, R; Scheid, D1
Moyes, IC; Moyes, R1
Baumann, P; Cuendet, C; Eap, CB1
Lüllmann-Rauch, R1
Alibert-Franco, S; Barbe, J; Brouant, P; Castaing, M; Loiseau, A; Mahamoud, A; Santelli, M; Santelli-Rouvier, C1
Ghafourifar, P; Mousavizadeh, K; Sadeghi-Nejad, H1
Cai, Y; Ruan, J; Tang, Y; Xiong, C1

Reviews

2 review(s) available for thioridazine and clomipramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction.
    European journal of medicinal chemistry, 2021, Nov-05, Volume: 223

    Topics: Antibodies; Ebolavirus; Glycoproteins; Hemorrhagic Fever, Ebola; Humans; Molecular Docking Simulation; Niemann-Pick C1 Protein; Protein Binding; Small Molecule Libraries; Virus Internalization

2021

Other Studies

23 other study(ies) available for thioridazine and clomipramine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Small Molecule Enhancement of 20S Proteasome Activity Targets Intrinsically Disordered Proteins.
    ACS chemical biology, 2017, 09-15, Volume: 12, Issue:9

    Topics: alpha-Synuclein; Cell Line, Tumor; Chlorpromazine; HEK293 Cells; Humans; Intrinsically Disordered Proteins; Molecular Docking Simulation; Oxidative Stress; Proteasome Endopeptidase Complex; Proteolysis; Small Molecule Libraries; tau Proteins

2017
Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.
    Journal of medicinal chemistry, 2018, 06-14, Volume: 61, Issue:11

    Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Binding Sites; Drug Design; Ebolavirus; Glycoproteins; Models, Molecular; Protein Binding; Protein Conformation; Viral Proteins

2018
Discovery of potent ebola entry inhibitors with (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold.
    European journal of medicinal chemistry, 2022, Oct-05, Volume: 240

    Topics: Antiviral Agents; Ebolavirus; Hemorrhagic Fever, Ebola; HIV Fusion Inhibitors; Humans; Molecular Docking Simulation; Virus Internalization

2022
Prolongation of the ejaculation latency in the male rat by thioridazine and chlorimipramine.
    Psychopharmacology, 1979, Volume: 65, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Clomipramine; Ejaculation; Male; Phenoxybenzamine; Phentolamine; Rats; Serotonin Antagonists; Sexual Behavior, Animal; Thioridazine; Time Factors

1979
Intraalveolar foam cells associated with lipidosis-like alterations in lung and liver of rats treated with tricyclic psychotropic drugs.
    Virchows Archiv. B, Cell pathology, 1975, Nov-21, Volume: 19, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Dibenzocycloheptenes; Endoplasmic Reticulum; Female; Imipramine; Inclusion Bodies; Iprindole; Lipidoses; Liver; Macrophages; Male; Pulmonary Alveoli; Rats; Thioridazine

1975
Urinary adenosine 3',5'-cyclic monophosphate: effects of electroconvulsive therapy.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 129

    Topics: Clomipramine; Cyclic AMP; Depression; Electroconvulsive Therapy; Humans; Psychiatric Status Rating Scales; Thioridazine; Time Factors

1976
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:2

    Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine

1988
Lipidosis-like ultrastructural alterations in rat lymph nodes after treatment with tricyclic antidepressants or neuroleptics.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 286, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Dibenzocycloheptenes; Female; Imipramine; Inclusion Bodies; Iprindole; Lipidoses; Lymph Nodes; Lymphocytes; Male; Microscopy, Electron; Rats; Thioridazine

1974
Membrane permeation by multidrug-resistance-modulators and non-modulators: effects of hydrophobicity and electric charge.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:3

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Antiparasitic Agents; Buffers; Calcium Channel Blockers; Chemical Phenomena; Chemistry, Physical; Clomipramine; Drug Resistance, Multiple; Lipid Bilayers; Liposomes; Octanols; Permeability; Pharmaceutical Preparations; Steroids; Thioridazine

2000
Calcium channel blocking activity of thioridazine, clomipramine and fluoxetine in isolated rat vas deferens: a relative potency measurement study.
    The Journal of urology, 2002, Volume: 168, Issue:6

    Topics: Animals; Antidepressive Agents; Calcium; Calcium Channel Blockers; Clomipramine; Dose-Response Relationship, Drug; Fluoxetine; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Thioridazine; Vas Deferens

2002
Extraction and determination of some psychotropic drugs in urine samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 2009, Feb-20, Volume: 49, Issue:2

    Topics: Amitriptyline; Calibration; Chromatography, High Pressure Liquid; Clomipramine; Drug Combinations; Drug Stability; Drug Storage; Female; Freezing; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Psychotropic Drugs; Reference Standards; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Thioridazine; Time Factors

2009