Page last updated: 2024-08-16

thioridazine and atropine

thioridazine has been researched along with atropine in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199026 (66.67)18.7374
1990's1 (2.56)18.2507
2000's7 (17.95)29.6817
2010's5 (12.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Andrews, PR; Craik, DJ; Martin, JL1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Uchida, M1
Bolden, C; Cusack, B; Richelson, E1
Cubeddu, LX; Mailman, RB; Niedzwiecki, DM1
Hiley, CR; Miller, RJ1
Del Rio, J; Fuentes, JA1
Linnoila, M; Mäki, M1
Clarke, GM; Hollow, VM; Weekes, JW1
Haffner, JF; Landmark, K1
O'Keeffe, R; Sharman, DF; Vogt, M1
Landmark, K2
Rao, HN; Tonapi, GT1
Chatterjee, S; Grinspoon, L; Ohler, J; Shader, R1
Senault, B1
Houser, J; Jaramillo, J; Kruger, S; Mattes, LM; Spoto, E1
Alender, CB; Feigen, GA; Sanz, E1
Carino, MA; Horita, A; Lai, H; Sperry, R1
de Belleroche, JS; Neal, MJ1
Erickson, CK; Goldman, ME1
LEME, JG; ROCHAESILVA, M1
COHLER, J; ELASHOFF, R; GRINSPOON, L; SHADER, RI1
CHATTERJEE, S; COHLER, J; GRINSPOON, L; SHADER, RI1
RUDOLPH, AS; SEWELL, HH; WHITE, RP1
LAVERTY, R; SHARMAN, DF1

Reviews

1 review(s) available for thioridazine and atropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for thioridazine and atropine

ArticleYear
Acute effects of alcohol, diazepam, thioridazine, flupenthixole and atropine on psychomotor performance profiles.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:4

    Topics: Adult; Atropine; Attention; Auditory Perception; Diazepam; Drug Interactions; Ethanol; Female; Humans; Male; Motor Activity; Piperazines; Placebos; Reaction Time; Statistics as Topic; Thioridazine; Time Factors; Visual Perception; Xanthenes

1974
Behavioral correlates of the guessing game. Side effects and double-blind studies.
    Archives of general psychiatry, 1966, Volume: 15, Issue:3

    Topics: Atropine; Clinical Trials as Topic; Humans; Lactose; Male; Phenobarbital; Schizophrenia; Thioridazine

1966

Other Studies

36 other study(ies) available for thioridazine and atropine

ArticleYear
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:5

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship

1989
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Purification of histamine receptor (VI). An improved double labeling method with "double protection".
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:6

    Topics: Animals; Atropine; Cats; Dibenzylchlorethamine; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle, Smooth; Promethazine; Receptors, Histamine; Receptors, Histamine H1; Thioridazine

1977
Clozapine is a potent and selective muscarinic antagonist at the five cloned human muscarinic acetylcholine receptors expressed in CHO-K1 cells.
    European journal of pharmacology, 1991, Jan-03, Volume: 192, Issue:1

    Topics: Animals; Atropine; Cell Line; Chlorpromazine; Clozapine; Cricetinae; Cricetulus; Female; Humans; Parasympatholytics; Quinuclidinyl Benzilate; Receptors, Muscarinic; Thioridazine

1991
Comparative anticholinergic properties of thioridazine, mesoridazine and sulforidazine.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: Acetylcholine; Animals; Antidepressive Agents; Atropine; Binding, Competitive; Carbachol; Caudate Nucleus; Cell Membrane; Dopamine; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mesoridazine; Parasympatholytics; Phenothiazines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Thioridazine

1989
Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism.
    Nature, 1974, Apr-12, Volume: 248, Issue:449

    Topics: Adenylyl Cyclase Inhibitors; Animals; Atropine; Azirines; Benzoates; Benztropine; Cerebral Cortex; Corpus Striatum; Dibenzazepines; Ethanol; Extrapyramidal Tracts; In Vitro Techniques; Kinetics; Male; Parasympatholytics; Phenothiazines; Pimozide; Piperazines; Rats; Receptors, Drug; Spiro Compounds; Thioridazine; Thioxanthenes; Tranquilizing Agents; Trifluoperazine; Tritium

1974
Further studies on the antagonism of stereotyped behaviour induced by amphetamine.
    European journal of pharmacology, 1969, Volume: 8, Issue:1

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Benperidol; Chlorpromazine; Exploratory Behavior; Haloperidol; Male; Perphenazine; Phenothiazines; Phenoxybenzamine; Phentolamine; Pilocarpine; Promazine; Propranolol; Rats; Thioridazine; Tremorine; Trifluperidol

1969
Case report: thioridazine overdose.
    Anaesthesia and intensive care, 1974, Volume: 2, Issue:4

    Topics: Arrhythmias, Cardiac; Atropine; Electrocardiography; Female; Humans; Lidocaine; Middle Aged; Procainamide; Thioridazine

1974
Opposing anticholinergic and cardio-depressive effects of promazine and thioridazine in isolated rat atria.
    Acta pharmacologica et toxicologica, 1972, Volume: 31, Issue:5

    Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Atropine; Depression, Chemical; Electric Stimulation; Female; Heart Atria; Heart Rate; Promazine; Rats; Thioridazine

1972
Effect of drugs used in psychoses on cerebral dopamine metabolism.
    British journal of pharmacology, 1970, Volume: 38, Issue:2

    Topics: Animals; Atropine; Brain; Butyrophenones; Cats; Chlorpromazine; Dogs; Dopamine; Female; Haloperidol; Haplorhini; Hypothalamus; Indoles; Male; Mice; Norepinephrine; Parkinson Disease, Secondary; Phenoxybenzamine; Phenylacetates; Rabbits; Thioridazine; Tranquilizing Agents

1970
The action of promazine and thioridazine in isolated rat atria. 2. Effects of varying concentrations of potassium and sodium on automaticity, mechanical performance, refractoriness and excitability.
    European journal of pharmacology, 1972, Volume: 17, Issue:1

    Topics: Animals; Atropine; Depression, Chemical; Electric Stimulation; Female; Heart Atria; In Vitro Techniques; Muscle Contraction; Potassium; Promazine; Rats; Sodium; Thioridazine

1972
The action of promazine and thioridazine in isolated rat atria. 3. Effects of varying concentrations of calcium and different frequencies and strengths of stimulation on contractile force and excitability.
    European journal of pharmacology, 1972, Volume: 17, Issue:3

    Topics: Acetanilides; Amino Alcohols; Animals; Atropine; Calcium; Electric Stimulation; Heart Atria; In Vitro Techniques; Muscle Contraction; Osmolar Concentration; Promazine; Propylamines; Rats; Sympatholytics; Thioridazine

1972
Effect of tranquillizers on the heart of Periplaneta americana (L.).
    Comparative and general pharmacology, 1971, Volume: 2, Issue:8

    Topics: Animals; Atropine; Chlorpromazine; Cockroaches; Depression, Chemical; Drug Interactions; Ethyl Ethers; Female; Heart; Heart Rate; Hydroxyzine; In Vitro Techniques; Thioridazine; Tranquilizing Agents; Trifluoperazine

1971
[Intraspecific aggressive behavior induced by apomorphine in the rat].
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine

1970
The time course of distribution of antipyrine in dogs and its modification by drugs.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:1

    Topics: Animals; Antipyrine; Atropine; Blood; Blood Pressure; Cerebrospinal Fluid; Chlorpromazine; Cholecystectomy; Common Bile Duct; Dogs; Gastrectomy; In Vitro Techniques; Injections, Intravenous; Meningitis; Nephrectomy; Phentolamine; Portacaval Shunt, Surgical; Reserpine; Splenectomy; Thioridazine

1965
Studies on the mode of action of sea urchin toxin. I. Conditions affecting release of hiamine and other agents from isolated tissues.
    Toxicon : official journal of the International Society on Toxinology, 1966, Volume: 4, Issue:3

    Topics: Animals; Atropine; Blood Flow Velocity; Carbon; Chemical Precipitation; Chemistry Techniques, Analytical; Colon; Echinodermata; Ergolines; Guinea Pigs; Heart; Histamine; Ileum; Lung; Muscle Contraction; Muscle, Smooth; Phenylbutazone; Quaternary Ammonium Compounds; Rats; Sulfates; Temperature; Thioridazine; Toxins, Biological; Tripelennamine

1966
Effects of microinjection of 2-chloro-11 (2-dimethylaminoethoxy)-dibenzo[b,f]-thiepine (zotepine), thioridazine and haloperidol into the striatum and nucleus accumbens on stereotypic behaviour and motor activity.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:4

    Topics: Animals; Antipsychotic Agents; Atropine; Corpus Striatum; Dibenzothiepins; Haloperidol; Humans; Male; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Dopamine; Septal Nuclei; Stereotyped Behavior; Thioridazine

1981
The contrasting effects of neuroleptics on transmitter release from the nucleus accumbens and corpus striatum.
    Neuropharmacology, 1982, Volume: 21, Issue:6

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Atropine; Chlorpromazine; Clozapine; Corpus Striatum; Dopamine; Female; Haloperidol; Neurotransmitter Agents; Nucleus Accumbens; Potassium; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Dopamine; Septal Nuclei; Thioridazine

1982
Effects of acute and chronic administration of antidepressant drugs on the central cholinergic nervous system. Comparison with anticholinergic drugs.
    Neuropharmacology, 1983, Volume: 22, Issue:10

    Topics: Animals; Antidepressive Agents; Atropine; Behavior, Animal; Choline; Male; Oxotremorine; Parasympathetic Nervous System; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Thioridazine; Time Factors

1983
ANTAGONISTIS OF BRADYKININ.
    Medicina experimentalis : International journal of experimental medicine, 1963, Volume: 8

    Topics: Animals; Atropine; Bradykinin; Cyproheptadine; Diphenhydramine; Guanethidine; Guinea Pigs; Ileum; Imipramine; Phenothiazines; Phenoxybenzamine; Research; Sympatholytics; Thioridazine

1963
PHENOBARBITAL AND ATROPINE IN COMBINATION, AN ACTIVE CONTROL SUBSTANCE FOR PHENOTHIAZINE RESEARCH.
    Journal of psychiatric research, 1964, Volume: 2

    Topics: Atropine; Biomedical Research; Pharmacology; Phenobarbital; Phenothiazines; Psychopharmacology; Research; Thioridazine

1964
SIDE EFFECTS AND DOUBLE-BLIND STUDIES. I. A CLINICAL COMPARISON BETWEEN THIORIDAZINE HYDROCHLORIDE AND A COMBINATION OF PHENOBARBITAL AND ATROPINE SULFATE.
    Journal of psychiatric research, 1964, Volume: 2

    Topics: Atropine; Biomedical Research; Double-Blind Method; Drug Therapy; Phenobarbital; Placebos; Schizophrenia; Thioridazine; Toxicology

1964
DRUG-INDUCED DISSOCIATION BETWEEN EVOKED RETICULAR POTENTIALS AND THE EEG.
    Electroencephalography and clinical neurophysiology, 1965, Volume: 19

    Topics: Amphetamine; Amphetamines; Animals; Antidepressive Agents; Atropine; Brain; Caffeine; Catechols; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Electroencephalography; Electrophysiology; Hallucinogens; Humans; Imipramine; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pentylenetetrazole; Phenoxybenzamine; Rabbits; Research; Reticular Formation; Scopolamine; Thioridazine; Tranquilizing Agents

1965
MODIFICATION BY DRUGS OF THE METABOLISM OF 3,4-DIHYDROXYPHENYLETHYLAMINE, NORADRENALINE AND 5-HYDROXYTRYPTAMINE IN THE BRAIN.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Animals; Atropine; Behavior, Animal; Brain; Brain Chemistry; Cats; Caudate Nucleus; Cerebral Cortex; Chlorpromazine; Chromatography; Dextroamphetamine; Dihydroxyphenylalanine; Dogs; Dopamine; Ephedrine; Fluorometry; Guanethidine; Morphine; Norepinephrine; Parasympatholytics; Parkinsonian Disorders; Pharmacology; Phenobarbital; Proteins; Rabbits; Radiometry; Research; Reserpine; Serotonin; Thalamus; Thioridazine; Trifluoperazine; Tritium

1965