Page last updated: 2024-08-22

thioridazine-5-sulfoxide and thioridazine

thioridazine-5-sulfoxide has been researched along with thioridazine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baumann, P; Eap, CB; Koeb, L; Souche, A1
Buckley, DG; Curry, SH; Watkins, GM; Whelpton, R1
Hale, PW; Poklis, A3
Heath, A; MÃ¥rtensson, E; Svensson, C1
Baumann, P; Eap, CB; Guentert, TW; Koeb, L; Powell, K; Schãublin-Loidl, M; Stabl, M1
Bonato, PS; Martinez, AS; Masetto de Gaitani, C1
Bonato, PS; Borges, KB; De Souza Borges, W; Pupo, MT1

Trials

1 trial(s) available for thioridazine-5-sulfoxide and thioridazine

ArticleYear
Plasma levels of the enantiomers of thioridazine, thioridazine 2-sulfoxide, thioridazine 2-sulfone, and thioridazine 5-sulfoxide in poor and extensive metabolizers of dextromethorphan and mephenytoin.
    Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Depressive Disorder; Dextromethorphan; Double-Blind Method; Female; Humans; Male; Mephenytoin; Mesoridazine; Middle Aged; Mixed Function Oxygenases; Phenothiazines; Stereoisomerism; Thioridazine

1996

Other Studies

8 other study(ies) available for thioridazine-5-sulfoxide and thioridazine

ArticleYear
Light-induced racemization: artifacts in the analysis of the diastereoisomeric pairs of thioridazine 5-sulfoxide in the plasma and urine of patients treated with thioridazine.
    Therapeutic drug monitoring, 1991, Volume: 13, Issue:4

    Topics: Adult; Antidepressive Agents; Chromatography, High Pressure Liquid; Female; Humans; Light; Male; Mental Disorders; Mesoridazine; Middle Aged; Phenothiazines; Stereoisomerism; Thioridazine

1991
Chromatographic separation of thioridazine sulphoxide and N-oxide diastereoisomers: identification as metabolites in the rat.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:7

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; In Vitro Techniques; Liver; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Stereoisomerism; Thioridazine

1986
Cardiotoxicity of thioridazine and two stereoisomeric forms of thioridazine 5-sulfoxide in the isolated perfused rat heart.
    Toxicology and applied pharmacology, 1986, Volume: 86, Issue:1

    Topics: Animals; Coronary Circulation; Electrocardiography; Heart; Heart Rate; In Vitro Techniques; Isomerism; Male; Myocardial Contraction; Rats; Rats, Inbred Strains; Stereoisomerism; Thioridazine

1986
Thioridazine toxicity--an experimental cardiovascular study of thioridazine and its major metabolites in overdose.
    Veterinary and human toxicology, 1985, Volume: 27, Issue:2

    Topics: Animals; Cardiovascular System; Dogs; Electrocardiography; Female; Male; Tachycardia; Thioridazine

1985
Determination of diastereoisomeric pairs of thioridazine 5-sulfoxide by high-performance liquid chromatography.
    Journal of chromatography, 1984, Dec-12, Volume: 336, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; In Vitro Techniques; Kinetics; Stereoisomerism; Thioridazine

1984
Thioridazine-5-sulfoxide cardiotoxicity in the isolated, perfused rat heart.
    Toxicology letters, 1984, Volume: 21, Issue:1

    Topics: Animals; Electrocardiography; Heart; Heart Rate; In Vitro Techniques; Male; Perfusion; Quinidine; Rats; Rats, Inbred Strains; Thioridazine

1984
Study on thioridazine 5-sulfoxide epimerization and degradation by capillary electrophoresis.
    Electrophoresis, 2003, Volume: 24, Issue:15

    Topics: Cyclodextrins; Drug Stability; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Molecular Structure; Osmolar Concentration; Stereoisomerism; Temperature; Thioridazine; Ultraviolet Rays

2003
Stereoselective analysis of thioridazine-2-sulfoxide and thioridazine-5-sulfoxide: an investigation of rac-thioridazine biotransformation by some endophytic fungi.
    Journal of pharmaceutical and biomedical analysis, 2008, Apr-14, Volume: 46, Issue:5

    Topics: Amylose; Antipsychotic Agents; Aspergillus fumigatus; Asteraceae; Biotransformation; Buffers; Carbamates; Chromatography, High Pressure Liquid; Culture Media; Diethylamines; Ethanol; Ether; Fungi; Hexanes; Methanol; Phyllachorales; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet; Stereoisomerism; Thioridazine

2008