Compounds > thiophenes
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thiophenes and zileuton

thiophenes has been researched along with zileuton in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rainsford, KD; Smith, F; Ying, C1
Chordia, MD; Heasley, BH; Joshi, EM; Macdonald, TL1
Chandrasekaran, A; Jordan, R; Li, H; Markiewicz, V; Scatina, J; Shen, L; Tong, Z; Xiang, Q1
Chordia, MD; Li, F; Macdonald, TL; Woodling, KA1
Heasley, BH; Joshi, EM; Macdonald, TL1

Other Studies

5 other study(ies) available for thiophenes and zileuton

ArticleYear
Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: comparison with interleukin-1-synthesis inhibitors.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1

    Topics: Animals; Benzofurans; Enzyme-Linked Immunosorbent Assay; Hip Joint; Humans; Hydroxyurea; Indoles; Interleukin-1; Knee Joint; Lipoxygenase Inhibitors; Naphthalenes; Organ Culture Techniques; Oxindoles; Pyrazoles; Quinolines; Structure-Activity Relationship; Swine; Synovial Membrane; Tarsus, Animal; Thiazoles; Thiophenes

1996
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
    Chemical research in toxicology, 2004, Volume: 17, Issue:2

    Topics: Animals; Cell Line; Glutathione; Half-Life; Humans; Hydroxyurea; Liver; Magnetic Resonance Spectroscopy; Rats; Spectrometry, Mass, Electrospray Ionization; Thiophenes

2004
Effects of ertiprotafib on hepatic cytochrome P450 and peroxisomal enzymes in rats and dogs, and in rat and human primary hepatocytes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme System; Dogs; Enzyme Induction; Female; Glucuronosyltransferase; Hepatocytes; Humans; Hydroxyurea; Hypoglycemic Agents; Liver; Male; Microsomes, Liver; Organ Size; Peroxisomes; Phenylpropionates; Rats; RNA, Messenger; Thiazolidinediones; Thiophenes; Thyroid Gland

2007
Irreversible alkylation of human serum albumin by zileuton metabolite 2-acetylbenzothiophene-S-oxide: a potential model for hepatotoxicity.
    Chemical research in toxicology, 2007, Volume: 20, Issue:12

    Topics: Alkylation; Anti-Asthmatic Agents; Binding, Competitive; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Half-Life; Humans; Hydroxyurea; Ibuprofen; Models, Biological; Serum Albumin; Tandem Mass Spectrometry; Thiophenes; Warfarin

2007
2-ABT-S-oxide detoxification by glutathione S-transferases A1-1, M1-1 and P1-1: implications for toxicity associated with zileuton.
    Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:3

    Topics: Chromatography, Liquid; Glutathione Transferase; Hydroxyurea; Inactivation, Metabolic; Isoenzymes; Kinetics; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Thiophenes; Toxicity Tests

2009