thiophenes has been researched along with tyrosine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (17.14) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 7 (20.00) | 29.6817 |
| 2010's | 15 (42.86) | 24.3611 |
| 2020's | 3 (8.57) | 2.80 |
| Authors | Studies |
|---|---|
| Lines, DR; Waisman, HA | 1 |
| Jensen, RA | 1 |
| Schmit, JC; Zalkin, H | 1 |
| Gershbein, LL | 1 |
| Kinoshita, T; Nakayama, K; Sato, H; Seiki, M; Takino, T | 1 |
| Bryan, N; Zuckerman, SH | 1 |
| Brown, CL; Carpenter, G; Dempsey, PJ; Rudolph-Owen, LA; Vecchi, M | 1 |
| Albanell, J; Arribas, J; Baselga, J; Codony-Servat, J; Lopez-Talavera, JC | 1 |
| Jackson, M; Jenner, P; Treseder, SA | 1 |
| Auberger, P; Belhacène, N; Fromigué, O; Loubat, A; Louis, K; Mari, B; Shipp, M; Wu, E | 1 |
| LAX, SR; RAVEL, JM; SHIVE, W; SMITH, LC | 1 |
| EZEKIEL, DH | 1 |
| Inagaki, K; Iwamura, H; Komatsu, N; Naka, Y; Oda, T; Shinkai, H | 1 |
| Barki-Harrington, L; El-Shewy, HM; Kelly, FL; Luttrell, LM | 1 |
| Akyol, O; Armutcu, F; Aydogdu, I; Gurel, A; Iraz, M; Kotuk, M; Ozen, S; Turkoz, Y; Yildirim, Z | 1 |
| Critchley-Thorne, RJ; Holmes, SP; Lee, PP; Nacu, S; Weber, J; Yan, N | 1 |
| Huang, TF; Lin, CN; Lo, HM; Peng, HC; Wu, WB | 1 |
| Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Galuppo, M; Kapoor, A; Mazzon, E; Paterniti, I; Thiemermann, C | 1 |
| Du, Y; Liu, X | 1 |
| Banner, DW; Benz, J; Diederich, F; Haap, W; Holland, MC; Kaib, PS; Kuster, O; Mary, JL; Salonen, LM; Schweizer, WB | 1 |
| Bristot, L; Campo, G; Ferrari, R; Gambetti, S; Monti, M; Parrinello, G; Tebaldi, M; Valgimigli, M | 1 |
| Steinhubl, SR | 1 |
| Jarmuła, A; Rode, W | 1 |
| Anderson, JL; Bates, ER; Bode, C; Granger, CB; Huber, K; Kristensen, SD; Lopez Sendon, JL; Ohman, EM; Steg, PG; Tubaro, M; Valgimigli, M; Wallentin, L | 1 |
| Brzozowski, MJ; Jenner, P; Rose, S | 1 |
| Jiang, WG; Kynaston, HG; Sanders, AJ; Weeks, HP | 1 |
| Ide, M; Irie, M; Kamikawa, T; Kashiwagi, H; Miura, T; Morikami, K; Muraoka, T; Nakamura, M; Nishihara, M | 1 |
| Agarwal, AK; Garg, A; Sankella, S | 1 |
| Arnaboldi, S; Benincori, T; Cirilli, R; Grecchi, S; Mussini, PR; Sannicolò, F; Santagostini, L | 1 |
| Herrman, L; Kinkel, M; Muhlack, S; Müller, T | 1 |
| Cai, G; Guo, J; Kong, L; Ren, Y; Song, D; Yu, W; Zhang, W; Zhu, J | 1 |
| Cong, H; Fan, B; Gu, J; Wang, T; Zhong, W | 1 |
| Finn, DP; Gaspar, JC; Llorente-Berzal, A; Okine, BN; Roche, M | 1 |
| Bong, D; Floyd, C; Liao, S; Pino, MJ; Tan, K; Wu, C | 1 |
| Abdo, NYM; Mohareb, RM | 1 |
1 review(s) available for thiophenes and tyrosine
| Article | Year |
|---|---|
Antiplatelet and anticoagulation agents in acute coronary syndromes: what is the current status and what does the future hold?
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Anticoagulants; Aspirin; Drug Therapy, Combination; Enoxaparin; Eptifibatide; Fondaparinux; Heparin; Hirudins; Humans; Lactones; Peptide Fragments; Peptides; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polysaccharides; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Pyridines; Receptors, Thrombin; Recombinant Proteins; Thiophenes; Ticagrelor; Tirofiban; Tyrosine; Warfarin | 2014 |
1 trial(s) available for thiophenes and tyrosine
| Article | Year |
|---|---|
Prasugrel versus tirofiban bolus with or without short post-bolus infusion with or without concomitant prasugrel administration in patients with myocardial infarction undergoing coronary stenting: the FABOLUS PRO (Facilitation through Aggrastat By drOppin
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Italy; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Predictive Value of Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Stents; Thiophenes; Ticlopidine; Time Factors; Tirofiban; Treatment Outcome; Tyrosine | 2012 |
33 other study(ies) available for thiophenes and tyrosine
| Article | Year |
|---|---|
The effect of feeding -2-thienylalanine on phenylalanine metabolism in the rhesus monkey.
Topics: Alanine; Animals; Animals, Newborn; Body Height; Body Weight; Brain; Cephalometry; Depression, Chemical; Feeding Behavior; Haplorhini; Humans; Macaca; Phenylalanine; Phenylketonurias; Thiophenes; Tyrosine | 1973 |
Metabolic interlock. Regulatory interactions exerted between biochemical pathways.
Topics: Alanine; Bacillus subtilis; Cyclohexanecarboxylic Acids; Cyclohexanes; Diphosphates; Feedback; Histidine; Hydro-Lyases; Kinetics; Leucine; Metabolism; Methionine; Phenylalanine; Pyruvates; Thiophenes; Tryptophan; Tyrosine | 1969 |
Chorismate mutase-prephenate dehydratase. Phenylalanine-induced dimerization and its relationship to feedback inhibition.
Topics: Alanine; Allosteric Regulation; Bromine; Centrifugation, Density Gradient; Chromatography; Chromatography, Gel; Cyclohexanecarboxylic Acids; Cyclohexanes; Feedback; Genetics, Microbial; Hydro-Lyases; Hydrogen-Ion Concentration; Isomerases; Kinetics; Macromolecular Substances; Mercuribenzoates; Models, Biological; Molecular Weight; Mutation; Phenylalanine; Protein Binding; Pyruvates; Salmonella typhimurium; Thiophenes; Tyrosine; Ultracentrifugation | 1971 |
Liver regeneration in rats administered vitamin and amino acid antagonists and metal salts.
Topics: Alanine; Amino Acids; Animals; Ascorbic Acid; Biotin; Body Weight; Canavanine; Caproates; Citrates; Depression, Chemical; Diet; Glycoproteins; Hepatectomy; Imidazoles; Indoles; Iron; Liver Regeneration; Metals; Nicotinic Acids; Picolinic Acids; Pyridines; Quaternary Ammonium Compounds; Rats; Sulfates; Sulfonic Acids; Taurine; Thiophenes; Tyrosine | 1967 |
Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2.
Topics: Arginine; Binding Sites; Enzyme Activation; Enzyme Precursors; Furin; Gelatinases; Glycoproteins; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Phenylalanine; Protease Inhibitors; Proteins; Recombinant Fusion Proteins; Subtilisins; Thiophenes; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tyrosine | 1996 |
Inhibition of LDL oxidation and myeloperoxidase dependent tyrosyl radical formation by the selective estrogen receptor modulator raloxifene (LY139481 HCL).
Topics: Animals; Antioxidants; Copper; Dexamethasone; Estradiol; Estrogen Antagonists; Free Radicals; Horseradish Peroxidase; Humans; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Peroxidase; Phagocytosis; Piperidines; Probucol; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Thiobarbituric Acid Reactive Substances; Thiophenes; Tyrosine | 1996 |
Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin.
Topics: Amphiregulin; Animals; Arsenicals; EGF Family of Proteins; Enzyme Inhibitors; ErbB Receptors; Glycoproteins; Growth Substances; Intercellular Signaling Peptides and Proteins; Metalloendopeptidases; Mutation; Peptide Fragments; Phenylalanine; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Pyrrolidines; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-4; Receptors, Cell Surface; Thiocarbamates; Thiophenes; Tumor Cells, Cultured; Tyrosine; Vanadates | 1998 |
Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells.
Topics: Breast Neoplasms; Endopeptidases; Humans; Hydroxamic Acids; Metalloendopeptidases; Phenylalanine; Phosphorylation; Protease Inhibitors; Receptor, ErbB-2; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Tyrosine; Vanadates | 1999 |
The effects of central aromatic amino acid DOPA decarboxylase inhibition on the motor actions of L-DOPA and dopamine agonists in MPTP-treated primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Callithrix; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrazines; Levodopa; Male; Motor Activity; Quinolones; Quinpirole; Thiophenes; Tyrosine | 2000 |
Active stromelysin-3 (MMP-11) increases MCF-7 survival in three-dimensional Matrigel culture via activation of p42/p44 MAP-kinase.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Caspase Inhibitors; Cell Survival; Collagen; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Female; Humans; In Situ Nick-End Labeling; Laminin; Matrix Metalloproteinase 11; Metalloendopeptidases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphorylation; Protein Serine-Threonine Kinases; Proteoglycans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Thiophenes; Transfection; Tumor Cells, Cultured; Tyrosine | 2003 |
THE EFFECTS OF PHENYLALANINE AND TYROSINE ANALOGS ON THE SYNTHESIS AND ACTIVITY OF 3-DEOXY-D-ARABINO-HEPTULOSONIC ACID 7-PHOSPHATE SYNTHETASES.
Topics: Carbohydrate Metabolism; Enzyme Inhibitors; Escherichia coli; Ligases; Mutation; Naphthalenes; Pharmacology; Phenylalanine; Phosphates; Pyridines; Research; Thiazoles; Thiophenes; Tyrosine | 1964 |
FALSE FEEDBACK INHIBITION OF AROMATIC AMINO ACID BIOSYNTHESIS BY BETA-2-THIENYLALANINE.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Escherichia coli; Feedback; Ligases; Metabolism; Mutation; Pharmacology; Phenylalanine; Proteins; Research; RNA; Shikimic Acid; Thiophenes; Tryptophan; Tyrosine | 1965 |
Induction of megakaryocytopoiesis and thrombocytopoiesis by JTZ-132, a novel small molecule with thrombopoietin mimetic activities.
Topics: Animals; Biomimetic Materials; Blood Cell Count; Busulfan; Cell Differentiation; Cell Division; Cell Line, Tumor; Colony-Forming Units Assay; DNA-Binding Proteins; Erythropoietin; Humans; Interleukin-11; Janus Kinase 2; Male; Mice; Mice, Inbred BALB C; Milk Proteins; Oxadiazoles; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Recombinant Proteins; Signal Transduction; STAT5 Transcription Factor; Thiophenes; Thrombopoiesis; Thrombopoietin; Trans-Activators; Tyrosine | 2004 |
Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I.
Topics: Animals; Cell Line; Chlorocebus aethiops; Endocytosis; ErbB Receptors; Humans; Insulin-Like Growth Factor I; Metalloendopeptidases; Mice; Mitogen-Activated Protein Kinase 3; Paracrine Communication; Phenylalanine; Phosphorylation; Quinazolines; Rats; Receptors, Somatomedin; Tetradecanoylphorbol Acetate; Thiophenes; Tyrosine; Tyrphostins | 2004 |
Effects of aminoguanidine and antioxidant erdosteine on bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Drug Therapy, Combination; Glutathione Peroxidase; Guanidines; Male; Malondialdehyde; Nitric Oxide; Peroxidase; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioglycolates; Thiophenes; Tyrosine | 2004 |
Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma.
Topics: Antigens, CD; Biomarkers; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Survival; Down-Regulation; Furans; Humans; Immunologic Factors; Immunotherapy; In Vitro Techniques; Interferon-alpha; Killer Cells, Natural; Melanoma; Oligonucleotide Array Sequence Analysis; Phosphorylation; Signal Transduction; Skin Neoplasms; STAT1 Transcription Factor; Thiophenes; Tyrosine | 2007 |
2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion.
Topics: Animals; Chalcone; Collagen; Crotalid Venoms; Focal Adhesion Protein-Tyrosine Kinases; Humans; Inhibitory Concentration 50; Lectins, C-Type; Phosphorylation; Platelet Adhesiveness; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Tyrosine | 2009 |
Evidence for the role of peroxisome proliferator-activated receptor-beta/delta in the development of spinal cord injury.
Topics: Animals; Apoptosis; Cytokines; Enzyme Induction; Fas Ligand Protein; Male; Mice; Neutrophil Infiltration; Nitric Oxide Synthase; Peroxidase; PPAR delta; PPAR-beta; Spinal Cord Injuries; Sulfones; Thiazoles; Thiophenes; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
Study on the binding of chiral drug duloxetine hydrochloride to human serum albumin.
Topics: Binding, Competitive; Duloxetine Hydrochloride; Electrophoresis, Capillary; Humans; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Stereoisomerism; Thiophenes; Tyrosine | 2010 |
Molecular recognition at the active site of factor Xa: cation-π interactions, stacking on planar peptide surfaces, and replacement of structural water.
Topics: Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Factor Xa; Factor Xa Inhibitors; Humans; Isoxazoles; Molecular Conformation; Peptides; Serine Endopeptidases; Stereoisomerism; Thermodynamics; Thiophenes; Tyrosine; Water | 2012 |
The illusion of "optimal" platelet inhibition.
Topics: Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Blood Platelets; Cardiovascular Diseases; Coronary Artery Disease; Female; Humans; Male; Myocardial Infarction; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Stents; Thiophenes; Tirofiban; Tyrosine | 2012 |
Computational study of the effects of protein tyrosine nitrations on the catalytic activity of human thymidylate synthase.
Topics: Deoxyuracil Nucleotides; Humans; Models, Molecular; Molecular Dynamics Simulation; Protein Processing, Post-Translational; Quinazolines; Thiophenes; Thymidylate Synthase; Tyrosine | 2013 |
Inhibition of i-NOS but not n-NOS protects rat primary cell cultures against MPP(+)-induced neuronal toxicity.
Topics: Amidines; Animals; Antibodies, Monoclonal; Astrocytes; Benzylamines; Cell Count; Cells, Cultured; Dopaminergic Neurons; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Mesencephalon; Microglia; Neuroprotective Agents; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Parkinson Disease; Picolines; Primary Cell Culture; Rats, Wistar; Thiophenes; Tyrosine; Tyrosine 3-Monooxygenase | 2015 |
The Association Between WAVE1 and -3 and the ARP2/3 Complex in PC 3 Cells.
Topics: Actin Cytoskeleton; Actin-Related Protein 2-3 Complex; Actins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Knockdown Techniques; Humans; Indoles; Male; Neoplasm Invasiveness; Phenotype; Phosphorylation; Polymerization; Prostatic Neoplasms; Protein Binding; RNA Interference; Signal Transduction; Thiophenes; Tyrosine; Wiskott-Aldrich Syndrome Protein Family | 2016 |
Discovery of a potent and highly selective transforming growth factor β receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD).
Topics: Animals; Asparagine; Crystallography, X-Ray; Drug Design; Enzyme Assays; Humans; Hydrogen Bonding; MAP Kinase Kinase Kinases; Mice; Microsomes, Liver; Molecular Structure; Protein Kinase Inhibitors; Pyrimidinones; Serine; Solubility; Structure-Activity Relationship; Thiophenes; Tyrosine | 2016 |
Characterization of the Mouse and Human Monoacylglycerol O-Acyltransferase 1 (Mogat1) Promoter in Human Kidney Proximal Tubule and Rat Liver Cells.
Topics: Acyltransferases; Anilides; Animals; Blotting, Northern; Caco-2 Cells; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Computational Biology; HT29 Cells; Humans; Kidney Tubules, Proximal; Liver; Mice; Oxazoles; PPAR alpha; Promoter Regions, Genetic; Pyrimidines; Rats; Real-Time Polymerase Chain Reaction; Rosiglitazone; Sulfones; Thiazoles; Thiazolidinediones; Thiophenes; Tyrosine | 2016 |
"Inherently chiral" thiophene-based electrodes at work: a screening of enantioselection ability toward a series of pharmaceutically relevant phenolic or catecholic amino acids, amino esters, and amine.
Topics: Amines; Amino Acids; Catechols; Dihydroxyphenylalanine; Electrochemical Techniques; Electrodes; Epinephrine; Esters; Phenols; Stereoisomerism; Thiophenes; Tyrosine | 2016 |
Levodopa, placebo and rotigotine change biomarker levels for oxidative stress.
Topics: Aged; Analysis of Variance; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dipeptides; Dopamine Agents; Electrochemical Techniques; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Oxidative Stress; Parkinson Disease; Tetrahydronaphthalenes; Thiophenes; Time Factors; Tyrosine | 2017 |
Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Coumarins; Drug Discovery; Fluorescence; Humans; Membrane Potential, Mitochondrial; Mice; Mitochondria; Molecular Docking Simulation; Phosphorylation; Reactive Oxygen Species; Serine; STAT3 Transcription Factor; Thiophenes; Tyrosine | 2019 |
Oleic acid-induced perilipin 5 expression and lipid droplets formation are regulated by the PI3K/PPARα pathway in HepG2 cells.
Topics: Azo Compounds; Chromones; Gene Expression Regulation; Hep G2 Cells; Humans; Imidazoles; Lipid Droplets; Morpholines; Oleic Acid; Oxazoles; Perilipin-5; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; PPAR alpha; Pyridines; Staining and Labeling; Sulfones; Thiophenes; Tyrosine | 2019 |
Pharmacological Blockade of PPAR Isoforms Increases Conditioned Fear Responding in the Presence of Nociceptive Tone.
Topics: Analgesia; Anilides; Animals; Conditioning, Psychological; Extinction, Psychological; Fear; Formaldehyde; Freezing Reaction, Cataleptic; Gene Expression; Male; Nociceptive Pain; Oxazoles; PPAR alpha; PPAR delta; PPAR gamma; PPAR-beta; Rats; Rats, Sprague-Dawley; Sulfones; Thiophenes; Tyrosine | 2020 |
Probing biased activation of mu-opioid receptor by the biased agonist PZM21 using all atom molecular dynamics simulation.
Topics: Allosteric Regulation; Animals; Aspartic Acid; Cluster Analysis; Conserved Sequence; Crystallization; Humans; Ligands; Mice; Molecular Dynamics Simulation; Morphine; Principal Component Analysis; Protein Conformation; Receptors, Opioid, mu; Signal Transduction; Structural Homology, Protein; Thiophenes; Tyrosine; Urea; Water | 2021 |
Antiproliferative and Antiprostate Cancer Activities of Heterocyclic Compounds Derived from Cyclohexane-1,4-dione.
Topics: Antineoplastic Agents; Benzopyrans; Cell Line, Tumor; Cell Proliferation; Cyclohexanes; Drug Screening Assays, Antitumor; Ethylamines; Heterocyclic Compounds; Molecular Structure; Nitriles; Proto-Oncogene Proteins c-pim-1; Pyrans; Pyridines; Structure-Activity Relationship; Sulfur; Thiophenes; Tyrosine | 2022 |