Compounds > thiophenes
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thiophenes and thymidine monophosphate

thiophenes has been researched along with thymidine monophosphate in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertino, JR; Li, WW; Tong, WP1
Aherne, GW; Barnes, MJ; Calvete, JA; Estlin, EJ; Hardcastle, A; Lunec, J; McGuire, JJ; Newell, DR; Pearson, AD; Taylor, GA1
Assaraf, YG; Ifergan, I; Kadry, WN; Pinter, RY1
Waldman, AS; Wyatt, MD; Yang, Z1
Dong, Y; Guan, Z; Niu, B; Wang, J; Wang, X; Xu, L; Zhang, J; Zhang, T1

Other Studies

5 other study(ies) available for thiophenes and thymidine monophosphate

ArticleYear
Antitumor activity of antifolate inhibitors of thymidylate and purine synthesis in human soft tissue sarcoma cell lines with intrinsic resistance to methotrexate.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Biological Transport; Biotransformation; Cell Division; Cell Survival; Drug Resistance, Neoplasm; Folic Acid Antagonists; Humans; Indoles; Isoindoles; Kinetics; Methotrexate; Purines; Quinazolines; Sarcoma; Tetrahydrofolates; Thiophenes; Thymidine Monophosphate; Tumor Cells, Cultured

1995
Impact of polyglutamation on sensitivity to raltitrexed and methotrexate in relation to drug-induced inhibition of de novo thymidylate and purine biosynthesis in CCRF-CEM cell lines.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:9

    Topics: Biological Transport; Cell Division; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Growth Inhibitors; Humans; Inhibitory Concentration 50; Leukemia; Methotrexate; Peptide Synthases; Purines; Quinazolines; RNA, Messenger; Thiophenes; Thymidine Monophosphate; Thymidylate Synthase; Tumor Cells, Cultured

1999
Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets.
    Journal of theoretical biology, 2006, Jun-21, Volume: 240, Issue:4

    Topics: Antimetabolites, Antineoplastic; Computer Simulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Models, Chemical; Purines; Quinazolines; Signal Transduction; Tetrahydrofolates; Thiophenes; Thymidine Monophosphate

2006
DNA damage and homologous recombination signaling induced by thymidylate deprivation.
    Biochemical pharmacology, 2008, Oct-15, Volume: 76, Issue:8

    Topics: Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA Damage; DNA, Neoplasm; Flow Cytometry; Folic Acid; Folic Acid Antagonists; HeLa Cells; Humans; Nucleotides; Phosphorylation; Quinazolines; Rad51 Recombinase; Recombination, Genetic; Replication Protein A; Thiophenes; Thymidine Monophosphate; Thymidylate Synthase

2008
Raltitrexed's effect on the development of neural tube defects in mice is associated with DNA damage, apoptosis, and proliferation.
    Molecular and cellular biochemistry, 2015, Volume: 398, Issue:1-2

    Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Deoxyuracil Nucleotides; DNA Damage; Embryo, Mammalian; Female; Folic Acid Antagonists; Gestational Age; Histones; Injections, Intraperitoneal; Male; Mice, Inbred C57BL; Neural Tube Defects; Phosphorylation; Pregnancy; Protein Subunits; Quinazolines; Replication Protein A; Thiophenes; Thymidine Monophosphate; Thymidylate Synthase

2015