Page last updated: 2024-08-18

thiophenes and thromboxanes

thiophenes has been researched along with thromboxanes in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's3 (27.27)18.2507
2000's0 (0.00)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adolphson, RL; Conroy, MC; Schellenberg, RR; Thueson, DO1
Asai, F; Ito, T; Matsuda, K; Oshima, T; Ushiyama, S1
Darius, H; Ferber, H; Schrör, K; Smith, EF1
Gragnoli, G; Signorini, AM; Tanganelli, I1
d'Avenia, V; di Minno, G; Iovine, C; Mattioli, PL; Turco, S1
Kuhn, A; Sauerland, S; Schiffer, K; Schrör, K1
Asai, F; Matsuda, K; Nakagawa, A; Oshima, T; Sugidachi, A; Takasaki, W; Tanaka, Y; Ushiyama, S1
Bhavaraju, K; Gartner, TK; Georgakis, A; Jin, J; Kunapuli, SP; Nurden, A; Nurden, P; Tomiyama, Y1
Dhanji, AR; Kirkby, NS; Leadbeater, PD; Milne, GL; Mitchell, JA; Thomas, S; Tucker, AT; Warner, TD1
Bray, P; Dangelmaier, C; Jin, J; Kunapuli, SP; Liverani, E; Manne, BK1
Badolia, R; Borst, O; Campbell, RA; Kunapuli, SP; Manne, BK; Middleton, E; Münzer, P; Rondina, MT; Walker-Allgaier, B; Weyrich, AS1

Trials

1 trial(s) available for thiophenes and thromboxanes

ArticleYear
Antagonism of P2Y₁₂ reduces physiological thromboxane levels.
    Platelets, 2010, Volume: 21, Issue:8

    Topics: Adenosine Diphosphate; Adolescent; Adult; Animals; Blood Platelets; Clopidogrel; Female; Humans; Male; Mice; Mice, Knockout; Middle Aged; Pilot Projects; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Thromboxanes; Ticlopidine; Young Adult

2010

Other Studies

10 other study(ies) available for thiophenes and thromboxanes

ArticleYear
CI-959, a new, potential antiallergic drug, inhibits mediator release from lung and contractions of human airways in vitro.
    International archives of allergy and applied immunology, 1990, Volume: 93, Issue:2-3

    Topics: Animals; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Histamine Antagonists; Histamine Release; Humans; Immunoglobulin E; Leukotrienes; Lung; Tetrazoles; Thiophenes; Thromboxanes

1990
In vitro antiplatelet profiles of the new thromboxane synthetase inhibitor sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Dogs; Humans; Imidazoles; In Vitro Techniques; Male; Methacrylates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1991
Inhibition of thromboxane and 12-HPETE formation by dazoxiben and its two thiophenic acid-substituted derivatives.
    European journal of pharmacology, 1985, Jun-07, Volume: 112, Issue:2

    Topics: Animals; Arachidonic Acids; Blood Platelets; Cattle; Epoprostenol; Humans; Imidazoles; In Vitro Techniques; Leukotrienes; Oxidoreductases; Platelet Aggregation; Rabbits; Thiophenes; Thromboxane-A Synthase; Thromboxanes; Vasoconstriction

1985
[Effects of ticlopidine on the plasma levels of beta-thromboglobulin and thromboxane B2 in types 1 and 2 diabetics].
    Minerva medica, 1984, Jul-31, Volume: 75, Issue:30-31

    Topics: Beta-Globulins; beta-Thromboglobulin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Thiophenes; Thromboxane B2; Thromboxanes; Ticlopidine

1984
Ex vivo effects of ticlopidine on human platelets: inhibition of fibrinogen binding by a mechanism independent of thromboxane formation.
    Agents and actions. Supplements, 1984, Volume: 15

    Topics: Anticoagulants; Blood Platelets; Fibrinogen; Humans; Platelet Aggregation; Thiophenes; Thromboxanes; Ticlopidine

1984
The action of non-steroidal antiinflammatory agents on platelet aggregation and vessel tone in relation to inhibition of PGI2- and thromboxane-release. With particular reference to 5-benzoyl-alpha-methyl-2-thiophene acetic acid (tiaprofenic acid).
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Cattle; Coronary Vessels; Epoprostenol; Guinea Pigs; Heart; In Vitro Techniques; Muscle Tonus; Muscle, Smooth, Vascular; Myocardium; Oxygen Consumption; Platelet Aggregation; Propionates; Prostaglandins; Rabbits; Thiophenes; Thromboxanes

1980
Superiority of plasma 11-dehydro-TXB2 to TXB2 as an index of in vivo TX formation in rabbits after dosing of CS-518, a TX synthase inhibitor.
    Thrombosis research, 1993, Jul-01, Volume: 71, Issue:1

    Topics: Animals; Arachidonic Acid; Eicosanoids; Immunoenzyme Techniques; Infusions, Intravenous; Male; Rabbits; Radioimmunoassay; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1993
Aspirin has little additional anti-platelet effect in healthy volunteers receiving prasugrel.
    Journal of thrombosis and haemostasis : JTH, 2011, Volume: 9, Issue:10

    Topics: Adolescent; Adult; Aspirin; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Thromboxanes

2011
PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses.
    Thrombosis and haemostasis, 2014, Mar-03, Volume: 111, Issue:3

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adaptor Proteins, Signal Transducing; Adenosine Triphosphate; Blood Platelets; Cells, Cultured; Clot Retraction; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Oncogene Protein v-akt; Phosphorylation; Platelet Activation; Pyrimidines; Receptors, Thrombin; Serine; Signal Transduction; Thiophenes; Threonine; Thromboxanes

2014
PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway.
    Journal of thrombosis and haemostasis : JTH, 2018, Volume: 16, Issue:6

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Blood Platelets; Disease Models, Animal; Humans; Mice, Knockout; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-raf; Pulmonary Embolism; Pyrimidines; Signal Transduction; Thiophenes; Thrombosis; Thromboxanes

2018