thiophenes has been researched along with thromboxane b2 in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (42.11) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asai, F; Ito, T; Matsuda, K; Oshima, T; Ushiyama, S | 1 |
| Arnout, J; Deckmyn, H; Gresele, P; Vermylen, J | 1 |
| Campisi, D; Davì, G; Francavilla, G; Paterna, S; Pinto, A; Strano, A | 1 |
| Asai, F; Ito, T; Matsuda, K; Oshima, T; Terada, A; Ushiyama, S; Yamazaki, M | 1 |
| Imai, Y; Matsumura, H; Nishikawa, K; Terashita, Z | 1 |
| Gragnoli, G; Signorini, AM; Tanganelli, I | 1 |
| Abbate, R; Breschi, C; Costanzo, G; Favilla, S; Gensini, GF; Neri Serneri, GG | 1 |
| Kawai, C | 1 |
| Bruno, JJ; Chang, LF; McSpadden, MM; Yang, D | 1 |
| Inaba, H; Kosuge, K; Mizuno, A; Nagashima, S; Nakashima, M; Uematsu, T | 1 |
| Kosuge, K; Matsuno, H; Nakashima, M; Takasaki, W; Tanaka, Y; Uematsu, T; Wada, K; Yamamura, N | 1 |
| Asai, F; Matsuda, K; Nakagawa, A; Oshima, T; Sugidachi, A; Takasaki, W; Tanaka, Y; Ushiyama, S | 1 |
| Farina, PR; Graham, AG; Gundel, RH; Hattox, SE; Homon, CA; Lazer, ES; Riska, PS; Wegner, CD | 1 |
| Chou, TC; Ding, YA; Hsu, LY; Yen, MH | 1 |
| Eidenberger, T; Fellier, H; Sadjak, A; Supanz, S | 1 |
| Bailey, JE; Bleyaert, HF; Daniels, CA; Gillis, KD; Johnson, JC; Katz, TL; MacKay, RJ; Merritt, AM; Thompson, KC | 1 |
| Aquino, M; Bruno, I; Guerrero, MD; Payá, M; Riccio, R; Terencio, MC | 1 |
| Huang, TF; Lin, CN; Lo, HM; Peng, HC; Wu, WB | 1 |
| Amore, C; Dell'Elba, G; Di Santo, A; Evangelista, V; Martelli, N; Piccoli, A; Totani, L | 1 |
1 trial(s) available for thiophenes and thromboxane b2
| Article | Year |
|---|---|
Ticlopidine activity on platelet function in patients with enhanced platelet aggregation. A short-term crossover study.
Topics: Adenosine Diphosphate; Adult; Aged; beta-Thromboglobulin; Bleeding Time; Blood Platelets; Collagen; Epoprostenol; Humans; Male; Middle Aged; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Thiophenes; Thromboxane B2; Ticlopidine | 1983 |
18 other study(ies) available for thiophenes and thromboxane b2
| Article | Year |
|---|---|
In vitro antiplatelet profiles of the new thromboxane synthetase inhibitor sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Dogs; Humans; Imidazoles; In Vitro Techniques; Male; Methacrylates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1991 |
L-652,343, a novel dual cyclo/lipoxygenase inhibitor, inhibits LTB4-production by stimulated human polymorphonuclear cells but not by stimulated human whole blood.
Topics: Calcimycin; Cyclooxygenase Inhibitors; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Thiophenes; Thromboxane B2 | 1987 |
Inhibition of platelet function by ticlopidine in arteriosclerosis obliterans of the lower limbs.
Topics: Aged; Arteriosclerosis Obliterans; beta-Thromboglobulin; Blood Platelets; Double-Blind Method; Drug Synergism; Epoprostenol; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4; Thiophenes; Thromboxane B2; Ticlopidine | 1985 |
RS-5186, a novel thromboxane synthetase inhibitor with a potent and extended duration of action.
Topics: Animals; Arachidonic Acids; Blood Platelets; Dogs; Female; Humans; In Vitro Techniques; Male; Microsomes; Platelet Count; Prostaglandins; Rabbits; Rats; Rats, Inbred Strains; Thiophenes; Thrombosis; Thromboxane B2; Thromboxane-A Synthase | 1988 |
[Antagonism of collagen-induced ECG changes in rats by a thromboxane synthetase inhibitor, CV-4151].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Collagen; Coronary Disease; Electrocardiography; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Humans; Pyridines; Rats; Rats, Inbred Strains; Thiophenes; Thromboxane B2; Ticlopidine | 1986 |
[Effects of ticlopidine on the plasma levels of beta-thromboglobulin and thromboxane B2 in types 1 and 2 diabetics].
Topics: Beta-Globulins; beta-Thromboglobulin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Thiophenes; Thromboxane B2; Thromboxanes; Ticlopidine | 1984 |
New horizons in cardiology.
Topics: Adult; Angina, Unstable; Anticoagulants; Coronary Disease; Coronary Vessels; Electrocardiography; Female; Humans; Male; Methacrylates; Middle Aged; Myocardial Infarction; Perfusion; Stroke Volume; Thiophenes; Thromboxane A2; Thromboxane B2; Ticlopidine; Tomography, Emission-Computed; Urokinase-Type Plasminogen Activator | 1984 |
The effect of oral ticlopidine on arachidonic acid products in human platelets.
Topics: Administration, Oral; Anticoagulants; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Humans; Malondialdehyde; Platelet Aggregation; Thiophenes; Thromboxane B2; Ticlopidine | 1984 |
Pharmacokinetic and pharmacodynamic profiles of CS-518, a selective, long-lasting thromboxane synthase inhibitor, after single and multiple oral administration to healthy volunteers.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Administration, Oral; Adult; Drug Administration Schedule; Eating; Half-Life; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiophenes; Thromboxane B2; Thromboxane-A Synthase | 1994 |
Changes in plasma and urinary 11-dehydrothromboxane B2 in healthy subjects produced by oral CS-518, a novel thromboxane synthase inhibitor.
Topics: Administration, Oral; Adult; Half-Life; Humans; Male; Thiophenes; Thromboxane B2; Thromboxane-A Synthase | 1993 |
Superiority of plasma 11-dehydro-TXB2 to TXB2 as an index of in vivo TX formation in rabbits after dosing of CS-518, a TX synthase inhibitor.
Topics: Animals; Arachidonic Acid; Eicosanoids; Immunoenzyme Techniques; Infusions, Intravenous; Male; Rabbits; Radioimmunoassay; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1993 |
A prodrug of a 2,6-disubstituted 4-(2-arylethenyl)phenol is a selective and orally active 5-lipoxygenase inhibitor.
Topics: Animals; Antigens; Biological Availability; Calcimycin; Female; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Macaca fascicularis; Male; Phenols; Prodrugs; Saimiri; SRS-A; Thiophenes; Thromboxane B2 | 1993 |
The inhibitory effect of 2-thienyl 2'-hydroxyphenyl ketone (C85) on platelet thromboxane formation.
Topics: Adenosine Triphosphate; Animals; Blood Platelets; Calcium; Dinoprostone; Fura-2; Humans; Ketones; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiophenes; Thromboxane B2 | 1996 |
Effects of the novel thromboxane (TXA2) receptor antagonist linotroban on inulin and para-aminohippuric acid clearances in the conscious male and female rat.
Topics: Acetates; Animals; Area Under Curve; Circadian Rhythm; Female; Glomerular Filtration Rate; Inulin; Male; p-Aminohippuric Acid; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Thiophenes; Thromboxane B2; Urination | 1997 |
Effect of eltenac in horses with induced endotoxaemia.
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Toxins; Cross-Over Studies; Endotoxemia; Escherichia coli Infections; Horse Diseases; Horses; Injections, Intravenous; Plasma; Prostaglandins; Pulmonary Wedge Pressure; Random Allocation; Respiration; Thiophenes; Thromboxane B2 | 2000 |
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression.
Topics: 4-Butyrolactone; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Behavior, Animal; Blood Platelets; Cattle; Chronic Disease; Gene Expression Regulation, Enzymologic; Humans; Hyperalgesia; Inflammation; Intramolecular Oxidoreductases; Leukotriene B4; Male; Mice; Neutrophils; Prostaglandin-E Synthases; Thiophenes; Thromboxane B2 | 2009 |
2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion.
Topics: Animals; Chalcone; Collagen; Crotalid Venoms; Focal Adhesion Protein-Tyrosine Kinases; Humans; Inhibitory Concentration 50; Lectins, C-Type; Phosphorylation; Platelet Adhesiveness; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Tyrosine | 2009 |
Prasugrel inhibits platelet-leukocyte interaction and reduces inflammatory markers in a model of endotoxic shock in the mouse.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Biomarkers; Blood Platelets; Disease Models, Animal; Down-Regulation; Humans; Inflammation Mediators; Leukocytes; Macrophage-1 Antigen; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Piperazines; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Selenoprotein P; Shock, Septic; Thiophenes; Thromboxane B2; Tumor Necrosis Factor-alpha | 2012 |