Page last updated: 2024-08-18

thiophenes and thromboxane a2

thiophenes has been researched along with thromboxane a2 in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19909 (45.00)18.7374
1990's4 (20.00)18.2507
2000's4 (20.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abiko, Y; Ashida, SI1
Hashimoto, H; Hieda, N; Ito, T; Ogawa, K; Okumura, K; Satake, T; Toki, Y2
Hieda, N; Ito, T; Ogawa, K; Ogawa, T; Ozawa, T; Satake, T; Sugiyama, S; Toki, Y1
Verstraete, M1
Numano, F1
Gaillard, JL; Kher, A; Lecompte, T; Samama, M1
Kawai, C1
Andriani, A; Chiappetta, MG; Fabiani, M1
Iizuka, Y; Itoh, K; Mukaiyama, O; Satoh, Y; Yamaguchi, T1
Iizuka, Y; Itoh, K; Mukaiyama, O; Satoh, Y; Terada, A; Yamaguchi, T1
Hisamoto, M; Ikeda, T; Itoh, K; Matsuda, K; Mukaiyama, O; Satoh, Y; Yamaguchi, T; Yamamura, N1
Okamoto, H; Takeuchi, H; Tanabe, M; Yamazaki, M1
Amemiya, T; Fujimura, M; Ishiura, Y; Liu, Q; Matsuda, T; Myou, S; Nobata, K; Yamamori, C1
Fellier, H; Sadjak, A; Supanz, S1
Schieffer, B; Schmidt, B1
Grove, EL; Kristensen, SD1
Aylward, PE; Behan, MW; Chew, DP1
Barreiro, EJ; Brito, FC; Fraga, CA; Kummerle, AE; Lugnier, C; Miranda, AL1
Boyce, JA; Laidlaw, TM1

Reviews

8 review(s) available for thiophenes and thromboxane a2

ArticleYear
Rationale for the use of drugs inhibiting platelet function in claudicating patients with atherosclerotic leg arteries.
    Agents and actions. Supplements, 1984, Volume: 15

    Topics: Anticoagulants; Arteriosclerosis; beta-Thromboglobulin; Blood Platelets; Clinical Trials as Topic; Humans; Intermittent Claudication; Leg; Platelet Aggregation; Platelet Factor 4; Suloctidil; Thiophenes; Thrombosis; Thromboxane A2; Ticlopidine

1984
Cyclic nucleotides, prostaglandins, and ischemic heart disease.
    Advances in cyclic nucleotide and protein phosphorylation research, 1984, Volume: 17

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arteriosclerosis; Coronary Disease; Diet, Atherogenic; Myocardial Contraction; Myocardial Infarction; Nucleotides, Cyclic; Prostaglandins; Rabbits; Thiophenes; Thromboxane A2; Ticlopidine

1984
[Pharmacology of anti-platelet agents].
    Journal des maladies vasculaires, 1983, Volume: 8, Issue:1

    Topics: Animals; Anticoagulants; Aspirin; Blood Platelets; Cyclic AMP; Cyclooxygenase Inhibitors; Dipyridamole; Epoprostenol; Female; Fibrinolytic Agents; Humans; In Vitro Techniques; Intestinal Absorption; Kinetics; Male; Papio; Platelet Aggregation; Prostaglandin Antagonists; Rabbits; Sulfinpyrazone; Thiophenes; Thrombosis; Thromboxane A2; Ticlopidine

1983
[Platelet aggregation and antiaggregant drugs].
    Recenti progressi in medicina, 1982, Volume: 73, Issue:5

    Topics: Dipyridamole; Humans; Papaverine; Platelet Aggregation; Prostaglandins; Theophylline; Thiophenes; Thromboxane A2; Ticlopidine; Verapamil

1982
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
    Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2

2003
Update on oral antiplatelet therapy: principles, problems and promises.
    Future cardiology, 2009, Volume: 5, Issue:3

    Topics: Adenosine; Administration, Oral; Cardiovascular Diseases; Cilostazol; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Tetrazoles; Thiophenes; Thromboxane A2; Ticagrelor

2009
The role of antiplatelet therapy in the secondary prevention of coronary artery disease.
    Current opinion in cardiology, 2010, Volume: 25, Issue:4

    Topics: Adenosine; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Secondary Prevention; Thiophenes; Thromboxane A2; Ticagrelor; Ticlopidine

2010
Platelets in patients with aspirin-exacerbated respiratory disease.
    The Journal of allergy and clinical immunology, 2015, Volume: 135, Issue:6

    Topics: Animals; Aspirin; Asthma, Aspirin-Induced; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Clinical Trials as Topic; Eosinophils; Gene Expression; Humans; Leukotrienes; Oxazoles; Piperazines; Platelet Activating Factor; Platelet Activation; Prasugrel Hydrochloride; Receptors, Leukotriene; Thiophenes; Thromboxane A2

2015

Trials

1 trial(s) available for thiophenes and thromboxane a2

ArticleYear
Rationale for the use of drugs inhibiting platelet function in claudicating patients with atherosclerotic leg arteries.
    Agents and actions. Supplements, 1984, Volume: 15

    Topics: Anticoagulants; Arteriosclerosis; beta-Thromboglobulin; Blood Platelets; Clinical Trials as Topic; Humans; Intermittent Claudication; Leg; Platelet Aggregation; Platelet Factor 4; Suloctidil; Thiophenes; Thrombosis; Thromboxane A2; Ticlopidine

1984

Other Studies

12 other study(ies) available for thiophenes and thromboxane a2

ArticleYear
Inhibition of platelet aggregation by a new agent, Ticlopidine.
    Thrombosis and haemostasis, 1979, Feb-15, Volume: 40, Issue:3

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Cell Survival; Collagen; Male; Platelet Aggregation; Prostaglandins G; Pyridines; Rats; Thiophenes; Thrombin; Thromboxane A2

1979
Protective effects of a thromboxane synthetase inhibitor, a thromboxane antagonist, a lipoxygenase inhibitor and a leukotriene C4, D4 antagonist on myocardial injury caused by acute myocardial infarction in the canine heart.
    Japanese circulation journal, 1989, Volume: 53, Issue:9

    Topics: Animals; Arrhythmias, Cardiac; Benzoquinones; Cardiomyopathies; Chromones; Coronary Disease; Dogs; Hemorrhage; Lipoxygenase Inhibitors; Male; Myocardial Infarction; Myocardium; Neutrophils; Quinones; SRS-A; Thiophenes; Thromboxane A2; Thromboxane-A Synthase

1989
Myocardial salvage by a novel thromboxane A2 synthetase inhibitor in a canine coronary occlusion-reperfusion model.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Coronary Vessels; Dogs; Hemodynamics; In Vitro Techniques; Male; Neutrophils; Risk Factors; Thiophenes; Thromboxane A2; Thromboxane-A Synthase

1988
Effect of a novel thromboxane A2 synthetase inhibitor on ischemia-induced mitochondrial dysfunction in canine hearts.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:2

    Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Female; Heart Rate; In Vitro Techniques; Lysosomes; Male; Mitochondria, Heart; Oxygen Consumption; Thiophenes; Thromboxane A2; Thromboxane-A Synthase; Time Factors

1988
New horizons in cardiology.
    International journal of cardiology, 1984, Volume: 6, Issue:5

    Topics: Adult; Angina, Unstable; Anticoagulants; Coronary Disease; Coronary Vessels; Electrocardiography; Female; Humans; Male; Methacrylates; Middle Aged; Myocardial Infarction; Perfusion; Stroke Volume; Thiophenes; Thromboxane A2; Thromboxane B2; Ticlopidine; Tomography, Emission-Computed; Urokinase-Type Plasminogen Activator

1984
Effects of CS-518, a thromboxane synthase inhibitor, on eosinophil function.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Epoprostenol; Guinea Pigs; In Vitro Techniques; Male; Peroxidases; Platelet Activating Factor; Pulmonary Alveoli; Superoxides; Thiophenes; Thromboxane A2; Thromboxane-A Synthase

1993
Effects of CS-518, a thromboxane synthase inhibitor, on the asthmatic response.
    European journal of pharmacology, 1993, May-12, Volume: 236, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Chlorpheniramine; Disease Models, Animal; Guinea Pigs; Indomethacin; Male; Methacrylates; Ovalbumin; Propranolol; Prostaglandin Endoperoxides, Synthetic; SRS-A; Thiophenes; Thromboxane A2; Thromboxane-A Synthase; Vasoconstrictor Agents

1993
Alteration of eicosanoid production in the sensitized guinea pig lung by CS-518.
    European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

    Topics: Administration, Oral; Animals; Arachidonic Acid; Eicosanoids; Guinea Pigs; Histamine; Indomethacin; Lung; Male; Ovalbumin; Prostaglandins; Radioimmunoassay; SRS-A; Thiophenes; Thromboxane A2; Thromboxane-A Synthase; Vaccination

1993
Effects of thromboxane synthetase inhibitor (RS-5186) on experimentally-induced cerebral vasospasm.
    Neurological research, 1999, Volume: 21, Issue:5

    Topics: Animals; Basilar Artery; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoprostenol; Neuroprotective Agents; Subarachnoid Hemorrhage; Thiophenes; Thromboxane A2; Thromboxane-A Synthase; Vasospasm, Intracranial

1999
Effect of thromboxane synthase inhibitor, CS-518, on propranolol-induced bronchoconstriction in guinea pigs.
    Drugs under experimental and clinical research, 2000, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Bronchoconstriction; Enzyme Inhibitors; Guinea Pigs; Immunization, Passive; Male; Methacholine Chloride; Muscarinic Agonists; Propranolol; Respiration, Artificial; Thiophenes; Thromboxane A2; Thromboxane-A Synthase

2000
Determination of efficacy of linotroban by inducing a reduction of renal inulin/para-aminohippuric acid clearances with the thromboxane A2 mimetic U-46619 in the conscious female rat.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:9

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Animals; Female; Glomerular Filtration Rate; Inulin; p-Aminohippuric Acid; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Thiophenes; Thromboxane A2

2000
Novel thienylacylhydrazone derivatives inhibit platelet aggregation through cyclic nucleotides modulation and thromboxane A2 synthesis inhibition.
    European journal of pharmacology, 2010, Jul-25, Volume: 638, Issue:1-3

    Topics: Animals; Arachidonic Acid; Bleeding Time; Blood Platelets; Collagen; Female; Humans; Hydrazones; Male; Mice; Molecular Structure; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship; Thiophenes; Thrombin; Thromboxane A2

2010