Page last updated: 2024-08-18

thiophenes and thiophane

thiophenes has been researched along with thiophane in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (20.41)	18.7374
1990's	1 (2.04)	18.2507
2000's	12 (24.49)	29.6817
2010's	23 (46.94)	24.3611
2020's	3 (6.12)	2.80

Authors

Authors	Studies
Cain, WS; Turk, A	1
Bohnenstengel, F; Hofmann, U; Kroemer, HK; Ritter, CA; Sperker, B	1
El-Gogary, TM	1
Dressel, D; Grube, M; Kroemer, HK; Kunert-Keil, C; Ritter, CA; Sperker, B	1
Davis, TP; Nemeroff, CB; Ritchie, JC	1
RONCAGLI, G	1
ABREU, BE; ALEXANDER, WM; FAITH, HE; NEWBERNE, JW; WEAVER, LC	1
BAI, DL; KYI, ZY	1
Haupt, E; Lehnert, N; Praneeth, VK	1
Hayward, TC; Thurbide, KB	1
Brandau, S; Jørgensen, KA; Maerten, E	1
Basabe, P; Benéitez, MT; Díez, D; Garrido, NM; Marcos, IS; Urones, JG	1
LEHMANN, G; PETERSON, WG; RANDALL, LO	1
Aggarwal, VK; Bi, J	1
Li, JX; Wang, GW; Xu, Y	1
Balog, T; Marotti, T; Martin-Kleiner, I	1
Ballantine, S; Delves, C; Dombroski, B; Evans, B; Gross, J; Kranz, M; Miah, A; Neu, M; Schneck, J; Somers, DO; Villa, JP; Wall, M	1
Baur, X; Bittner, C	1
BAKER, BR; BROWN, GB	1
ARMSTRONG, MD; BROWN, GB	1
BAKER, BR; QUERRY, MV	2
Görls, H; Imhof, W; Klobes, O; Maiti, BK	1
Dalaloyan, AM; Goodwin, JA; Gulyan, GM; Kidd, BE; Kurtikyan, TS	1
Chernysheva, GA; Ivanov, IS; Kandalintseva, NV; Plotnikov, MB; Prosenko, AE; Smol'iakova, VI	2
Crosbie, E; García-Álvarez, P; Kennedy, AR; Klett, J; Mulvey, RE; Robertson, SD	1
EASTMAN, RH; WOODWARD, RB	1
Churin, AA; Fedorova, EP; Neupokoeva, OV; Prosenko, AE; Voronova, OL	1
Biswal, HS; Wategaonkar, S	1
Bouaziz, S; Broutin, I; Coric, P; Garbay, C; Gaucher, JF; Gautier, B; Goncalves, V; Huguenot, F; Inguimbert, N; Lesnard, A; Miteva, MA; Rault, S; Seijo, B; Vidal, M; Villoutreix, BO	1
Benetti, S; De Risi, C; Pollini, GP; Zanirato, V	1
Robertson, FJ; Wu, J	1
El-Serafi, I; Hagbjörk, AL; Hassan, M; Hassan, Z; Terelius, Y; Twelkmeyer, B	1
Azizyan, AS; Ford, PC; Iretskii, AV; Kurtikyan, TS; Martirosyan, GG	1
Bhattacharyya, S; Bhattacherjee, A; Shirhatti, PR; Wategaonkar, S	1
Fujiwara, Y; Ikeda, T; Kajimoto, T; Kudo, R; Murakami, K; Nohara, T; Ono, M; Takeya, M; Yamaguchi, K	1
Borah, M; Gogoi, P; Indukuri, K; Saikia, AK	1
Doud, E; Hawker, DD; Kelleher, NL; Le, HV; Liu, D; Sanishvili, R; Silverman, RB; Widom, J; Wu, R	1
Jiang, X; Li, B; Ma, S; Wang, R; Zhong, Y	1
El-Aasr, M; Fujiwara, Y; Ikeda, T; Kinjo, J; Murakami, K; Nakano, D; Nohara, T; Ono, M	1
D'yakonov, VA; Dzhemilev, UM; Islamov, II; Khalilov, LM; Tuktarova, RA	1
Churin, AA; Neupokoeva, OV; Shilova, IV; Suslov, NI; Voronova, OL	1
Albrecht, Ł; Kowalczyk, R; Przydacz, A	1
Abedi-Valugerdi, M; El-Serafi, I; Hassan, M; Mattsson, J; Moshfegh, A; Naughton, S; Potácová, Z; Saghafian, M; Terelius, Y	1
Aydın, EB; Aydın, M; Sezgintürk, MK	1
Contini, C; Galassi, R; Gambi, E; Manca, G; Pucci, M	1
Allen, RA; Carden, RG; Feliciano, JA; Leitgeb, AJ; Minbiole, KPC; Schrank, CL; Wuest, WM	1
Jakubowski, M; Jarzęcki, AA; Kaszuba, A; Sitkowski, J; Wojtczak, A; Łakomska, I	1

Reviews

2 review(s) available for thiophenes and thiophane

Article	Year
Smell of danger: an analysis of LP-gas odorization. American Industrial Hygiene Association journal, 1985, Volume: 46, Issue:3 Topics: Diffusion; Explosions; Humans; Odorants; Olfaction Disorders; Petroleum; Psychophysics; Sensory Thresholds; Sex Factors; Smell; Sulfhydryl Compounds; Thiophenes; Time Factors	1985
Synthetic routes to chiral nonracemic and racemic dihydro- and tetrahydrothiophenes. Chemical reviews, 2012, Apr-11, Volume: 112, Issue:4 Topics: Chemistry Techniques, Synthetic; Molecular Structure; Stereoisomerism; Thiophenes	2012

Other Studies

47 other study(ies) available for thiophenes and thiophane

Article	Year
Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method. Journal of chromatography. B, Biomedical sciences and applications, 1999, Jun-25, Volume: 730, Issue:1 Topics: Antineoplastic Agents, Alkylating; Biomarkers; Busulfan; Calibration; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Kinetics; Liver; Reproducibility of Results; Sensitivity and Specificity; Thiophenes	1999
Ab-initio molecular geometry and normal coordinate analysis of tetrahydrothiophene molecule. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2001, Volume: 57, Issue:7 Topics: Models, Chemical; Molecular Structure; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Thiophenes	2001
Overexpression of glutathione S-transferase A1-1 in ECV 304 cells protects against busulfan mediated G2-arrest and induces tissue factor expression. British journal of pharmacology, 2002, Volume: 137, Issue:7 Topics: Blotting, Western; Busulfan; Cell Cycle; Cell Division; Cell Line; DNA, Complementary; Dose-Response Relationship, Drug; G2 Phase; Glutathione Transferase; Humans; Isoenzymes; Plasmids; Thiophenes; Thromboplastin; Time Factors; Transfection	2002
Action of three ectopeptidases on corticotropin-releasing factor: metabolism and functional aspects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:1 Topics: Adrenocorticotropic Hormone; Algorithms; Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; CD13 Antigens; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Corticotropin-Releasing Hormone; Glycopeptides; Hypothalamus; In Vitro Techniques; Kinetics; Leucine; Male; Molecular Sequence Data; Neprilysin; Peptidyl-Dipeptidase A; Pituitary Gland; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Thiophenes	2003
[Renal effects of controlled hypotension with a thiophane derivative]. Minerva anestesiologica, 1957, Volume: 23, Issue:11 Topics: Autonomic Agents; Hypotension; Hypotension, Controlled; Kidney; Thiophenes	1957
Pharmacology of some monohalogenated derivatives of sulfolane (tetrahydrothiophene-1,1-dioxide). Archives internationales de pharmacodynamie et de therapie, 1959, Apr-01, Volume: 119, Issue:3-4 Topics: Oxygen Compounds; Thiophenes	1959
[CHEMOTHERAPEUTIC STUDIES ON SCHISTOSOMIASIS. X. SOME AMIDES DERIVED FROM THIOPHENE-2-CARBOXYLIC, THIOPHENE-2-SULPHONIC ACID AND TETRAHYDROTHIOPHENE-2,5- DICARBOXYLIC ACID]. Yao xue xue bao = Acta pharmaceutica Sinica, 1962, Volume: 9 Topics: Amides; Antiprotozoal Agents; Carboxylic Acids; Chemistry, Pharmaceutical; Dicarboxylic Acids; Pharmacology; Research; Schistosomiasis; Sulfonic Acids; Thiophenes	1962
Thiolate coordination to Fe(II)-porphyrin NO centers. Journal of inorganic biochemistry, 2005, Volume: 99, Issue:4 Topics: Cysteine; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Ferric Compounds; Imidazoles; Ligands; Metalloporphyrins; Models, Biological; Models, Molecular; Nitric Oxide; Phenols; Porphyrins; Sulfhydryl Compounds; Thiophenes	2005
Characteristics of sulfur response in a micro-flame photometric detector. Journal of chromatography. A, 2006, Feb-10, Volume: 1105, Issue:1-2 Topics: Microchemistry; Photometry; Sulfhydryl Compounds; Sulfides; Sulfur; Thiophenes	2006
Asymmetric synthesis of highly functionalized tetrahydrothiophenes by organocatalytic domino reactions. Journal of the American Chemical Society, 2006, Nov-22, Volume: 128, Issue:46 Topics: Catalysis; Catalytic Domain; Crystallography, X-Ray; Hydrogen Bonding; Thiophenes	2006
1-Hydroxymethyl-4-phenylsulfonybutadiene, a versatile building block for the synthesis of 2,3,4-trisusbtituted tetrahydrothiophenes. Molecules (Basel, Switzerland), 2004, Apr-30, Volume: 9, Issue:5 Topics: Butadienes; Models, Chemical; Molecular Structure; Stereoisomerism; Sulfones; Thiophenes	2004
The ganglionic blocking action of thiophanium derivatives. The Journal of pharmacology and experimental therapeutics, 1949, Volume: 97, Issue:1 Topics: Central Nervous System Depressants; Ganglionic Blockers; Humans; Sympathetic Nervous System; Thiophenes	1949
Application of furyl-stabilized sulfur ylides to a concise synthesis of 8a-epi-swainsonine. Chemical communications (Cambridge, England), 2008, Jan-07, Issue:1 Topics: Aldehydes; Catalysis; Molecular Structure; Stereoisomerism; Sulfur Compounds; Swainsonine; Thiophenes	2008
Synthesis of C60-fused tetrahydrothiophene derivatives via nucleophilic cycloaddition of thiocyanates. Organic & biomolecular chemistry, 2008, Aug-21, Volume: 6, Issue:16 Topics: Cyclization; Fullerenes; Molecular Structure; Thiocyanates; Thiophenes	2008
Dynorphin inhibits NEP activity in R1.1 mouse thymoma cells. Cell biochemistry and function, 2008, Volume: 26, Issue:8 Topics: Animals; Cell Line, Tumor; Dynorphins; Mice; Naltrexone; Narcotic Antagonists; Neprilysin; Receptors, Opioid, kappa; Thiophenes; Thymoma; Thymus Neoplasms	2008
Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode. Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14 Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Models, Molecular; Molecular Structure; Mutation; Phosphodiesterase 4 Inhibitors; Protein Binding; Protein Conformation; Structure-Activity Relationship; Thiophenes	2009
Occupational obstructive airway diseases caused by the natural gas odorant tetrahydrothiophene--two case reports. American journal of industrial medicine, 2009, Volume: 52, Issue:12 Topics: Aged; Arrhythmias, Cardiac; Chest Pain; Cough; Fossil Fuels; Headache; Humans; Irritants; Lung Volume Measurements; Male; Middle Aged; Mucositis; Nausea; Neurotoxicity Syndromes; Occupational Diseases; Occupational Exposure; Odorants; Protective Clothing; Pulmonary Disease, Chronic Obstructive; Thiophenes; Vomiting	2009
Biotin; 3,4-trans-diaminothiophane. The Journal of organic chemistry, 1947, Volume: 12, Issue:1 Topics: Biotin; Humans; Thiophenes; Vitamin B Complex; Vitamins	1947
Biotin; 2-(delta-carboxybutyl) thiophane-3,4-dicarboxylic acid. The Journal of organic chemistry, 1947, Volume: 12, Issue:1 Topics: Acids; Biotin; Dicarboxylic Acids; Humans; Thiophenes; Vitamin B Complex; Vitamins	1947
Biotin; a second synthesis of 2-delta-carboxybutyl)-thiophane-3,4-dicarboxylic acid. The Journal of organic chemistry, 1947, Volume: 12, Issue:1 Topics: Acids; Biotin; Carboxylic Acids; Dicarboxylic Acids; Thiophenes; Vitamin B Complex; Vitamins	1947
Biotin; cis-3,4-diaminothiophane. The Journal of organic chemistry, 1947, Volume: 12, Issue:1 Topics: Biotin; Thiophenes; Vitamin B Complex; Vitamins	1947
A straightforward and generalizable synthetic methodology for the synthesis of ruthenium(II) complexes with thioether ligands from either Ru(III) or Ru(0) precursors. Dalton transactions (Cambridge, England : 2003), 2010, Jun-28, Volume: 39, Issue:24 Topics: Chloroform; Coordination Complexes; Crystallography, X-Ray; Formaldehyde; Ligands; Molecular Conformation; Ruthenium; Sulfides; Thiophenes	2010
Six-coordinate nitrosyl and nitro complexes of meso-tetratolylporphyrinatocobalt with trans sulfur-donor ligands. Inorganic chemistry, 2010, Sep-06, Volume: 49, Issue:17 Topics: Cobalt; Ligands; Metalloporphyrins; Nitro Compounds; Nitrogen Oxides; Spectroscopy, Fourier Transform Infrared; Sulfides; Sulfur; Thiophenes	2010
[Hemorheological effects of thiophane on tetrachloromethane induced hepatic damage]. Eksperimental'naia i klinicheskaia farmakologiia, 2010, Volume: 73, Issue:8 Topics: Animals; Blood Viscosity; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Erythrocyte Aggregation; Erythrocyte Deformability; Male; Rats; Rats, Wistar; Thiophenes	2010
Structurally engineered deprotonation/alumination of THF and THTP with retention of their cycloanionic structures. Angewandte Chemie (International ed. in English), 2010, Dec-03, Volume: 49, Issue:49 Topics: Aluminum; Anions; Crystallography, X-Ray; Cyclization; Furans; Models, Molecular; Molecular Structure; Organometallic Compounds; Protons; Thiophenes	2010
Tetrahydrothiophene (thiophane) derivatives. Journal of the American Chemical Society, 1946, Volume: 68, Issue:11 Topics: Thiophenes	1946
[Pharmacological correction of the cytogenetic effects of cisplatin]. Eksperimental'naia i klinicheskaia farmakologiia, 2010, Volume: 73, Issue:10 Topics: Animals; Bone Marrow; Chromosome Aberrations; Cisplatin; Male; Mice; Mutagens; Thiophenes; Time Factors	2010
OH···X (X = O, S) hydrogen bonding in thetrahydrofuran and tetrahydrothiophene. The Journal of chemical physics, 2011, Oct-07, Volume: 135, Issue:13 Topics: Cresols; Furans; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Thiophenes	2011
Targeting the proangiogenic VEGF-VEGFR protein-protein interface with drug-like compounds by in silico and in vitro screening. Chemistry & biology, 2011, Dec-23, Volume: 18, Issue:12 Topics: Angiogenesis Inhibitors; Binding Sites; Cells, Cultured; Drug Design; Human Umbilical Vein Endothelial Cells; Humans; Protein Interaction Mapping; Protein Structure, Tertiary; Receptors, Vascular Endothelial Growth Factor; Small Molecule Libraries; Thiophenes; Vascular Endothelial Growth Factor A	2011
[Hepatoprotective effect of thiophane in rats with experimental carbon tetrachloride-induced hepatitis]. Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:8 Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Carbohydrate Metabolism; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hepatitis, Animal; Inactivation, Metabolic; Lipid Metabolism; Liver; Male; Protective Agents; Rats; Rats, Wistar; Silymarin; Thiophenes; Triglycerides	2011
Phosphorothioic acids and related compounds as surrogates for H2S--synthesis of chiral tetrahydrothiophenes. Journal of the American Chemical Society, 2012, Feb-08, Volume: 134, Issue:5 Topics: Crystallography, X-Ray; Hydrogen Sulfide; Models, Molecular; Molecular Structure; Phosphates; Stereoisomerism; Thiophenes	2012
Gas chromatographic-mass spectrometry method for the detection of busulphan and its metabolites in plasma and urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jan-15, Volume: 913-914 Topics: Busulfan; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Reproducibility of Results; Thiophenes	2013
Weak coordination of neutral S- and O-donor proximal ligands to a ferrous porphyrin nitrosyl. Characterization of 6-coordinate complexes at low T. Journal of inorganic biochemistry, 2013, Volume: 121 Topics: Cold Temperature; Coordination Complexes; Furans; Kinetics; Ligands; Metalloporphyrins; Models, Chemical; Nitric Oxide; Pyrrolidines; Solutions; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Thiophenes	2013
O-H···S hydrogen bonds conform to the acid-base formalism. The journal of physical chemistry. A, 2013, Aug-29, Volume: 117, Issue:34 Topics: Furans; Hydrogen Bonding; Hydrogen Sulfide; Methanol; Models, Molecular; Molecular Conformation; Phenols; Spectrometry, Mass, Electrospray Ionization; Thermodynamics; Thiophenes; Water	2013
Isolation and characterization of new onionins A2 and A3 from Allium cepa, and of onionins A1, A2, and A3 from Allium fistulosum. Chemical & pharmaceutical bulletin, 2014, Volume: 62, Issue:11 Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents, Phytogenic; Cells, Cultured; Humans; Immunologic Factors; Macrophages; Onions; Plant Roots; Receptors, Cell Surface; Sulfenic Acids; Thiophenes	2014
Diastereoselective synthesis of substituted tetrahydrothiophenes and -thiopyrans via thia-Prins cyclization reaction. The Journal of organic chemistry, 2015, Mar-06, Volume: 80, Issue:5 Topics: Catalysis; Cyclization; Mesylates; Molecular Structure; Pyrans; Stereoisomerism; Sulfhydryl Compounds; Thiophenes; Trimethylsilyl Compounds	2015
Design and mechanism of tetrahydrothiophene-based γ-aminobutyric acid aminotransferase inactivators. Journal of the American Chemical Society, 2015, Apr-08, Volume: 137, Issue:13 Topics: 4-Aminobutyrate Transaminase; Drug Design; Enzyme Activation; Enzyme Inhibitors; gamma-Aminobutyric Acid; Kinetics; Models, Molecular; Protein Conformation; Thiophenes	2015
Diastereoselective Synthesis of Biheterocyclic Tetrahydrothiophene Derivatives via Base-Catalyzed Cascade Michael-Aldol [3 + 2] Annulation of 1,4-Dithiane-2,5-diol with Maleimides. The Journal of organic chemistry, 2015, Jul-02, Volume: 80, Issue:13 Topics: Catalysis; Heterocyclic Compounds; Maleimides; Molecular Structure; Stereoisomerism; Sulfur Compounds; Thiophenes	2015
Two new bicyclic sulfoxides from Welsh onion. Journal of natural medicines, 2016, Volume: 70, Issue:2 Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Proliferation; Humans; Macrophages; Neoplasms; Onions; Plant Extracts; Plant Roots; Sulfoxides; Thiophenes	2016
Catalytic cyclometallation in steroid chemistry IV: Efficient method for the synthesis of tetrahydrothiophene, tetrahydroselenophen and cyclopentanone derivatives of (5α)-cholestane. Steroids, 2016, Volume: 108 Topics: Catalysis; Chemistry Techniques, Synthetic; Cholestanes; Cyclopentanes; Organoselenium Compounds; Stereoisomerism; Thiophenes	2016
[EFFECT OF SYNTHETIC ANTIOXIADNT THIOPHAN AND SCUTELLARIA BAICALENSIS ROOT EXTRACT ON DRUG-INDUCED MUTAGENESIS]. Eksperimental'naia i klinicheskaia farmakologiia, 2015, Volume: 78, Issue:11 Topics: Animals; Antioxidants; Cisplatin; Cyclophosphamide; Drosophila melanogaster; Mutagenesis; Plant Extracts; Plant Roots; Scutellaria baicalensis; Thiophenes	2015
Brønsted-base-catalyzed remote cascade reactivity of 2,4-dienones - asymmetric synthesis of tetrahydrothiophenes. Organic & biomolecular chemistry, 2017, Nov-22, Volume: 15, Issue:45 Topics: Alkaloids; Catalysis; Ketones; Molecular Structure; Thiophenes	2017
Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway. PloS one, 2017, Volume: 12, Issue:11 Topics: Adolescent; Adult; Animals; Busulfan; Child; Child, Preschool; Gene Expression Regulation; Glutathione Transferase; Hematopoietic Stem Cell Transplantation; Humans; Kinetics; Male; Metabolic Networks and Pathways; Metabolome; Mice, Inbred C57BL; Microsomes; Middle Aged; Oxygenases; RNA, Messenger; Substrate Specificity; Thiophenes; Time Factors; Transplantation Conditioning; Voriconazole	2017
Ultrasensitive determination of cadherin-like protein 22 with a label-free electrochemical immunosensor using brush type poly(thiophene-g-glycidylmethacrylate) modified disposable ITO electrode. Talanta, 2019, Aug-01, Volume: 200 Topics: Biomarkers; Cadherins; Electrochemical Techniques; Electrodes; Epoxy Compounds; Humans; Immunoassay; Methacrylates; Molecular Structure; Particle Size; Polymers; Surface Properties; Thiophenes; Tin Compounds	2019
Odorant Monitoring in Natural Gas Pipelines Using Ultraviolet-Visible Spectroscopy. Applied spectroscopy, 2021, Volume: 75, Issue:2 Topics: Air Pollutants; Natural Gas; Odorants; Spectrophotometry, Ultraviolet; Thiophenes	2021
Trivalent sulfonium compounds (TSCs): Tetrahydrothiophene-based amphiphiles exhibit similar antimicrobial activity to analogous ammonium-based amphiphiles. Bioorganic & medicinal chemistry letters, 2021, 04-01, Volume: 37 Topics: Bacteria; Dose-Response Relationship, Drug; Erythrocytes; Humans; Microbial Sensitivity Tests; Molecular Structure; Quaternary Ammonium Compounds; Structure-Activity Relationship; Sulfonium Compounds; Surface-Active Agents; Thiophenes	2021
Factors Affecting the Stability of Platinum(II) Complexes with 1,2,4-Triazolo[1,5- International journal of molecular sciences, 2022, Mar-26, Volume: 23, Issue:7 Topics: Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Oxides; Platinum; Pyrimidines; Sulfoxides; Thiophenes; Triazoles	2022