Page last updated: 2024-08-18

thiophenes and thiazolidines

thiophenes has been researched along with thiazolidines in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (23.08)18.2507
2000's1 (7.69)29.6817
2010's6 (46.15)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Ascenzi, P; Bolognesi, M; Casale, E; Coda, A; La Rosa, C; Luisetti, M; Rizzi, M1
Ascenzi, P; Bolognesi, M; Djinovic Carugo, K; Fasano, M; La Rosa, C; Luisetti, M; Rizzi, M1
Beani, JC; Emonet, N; Favier, A; Leccia, MT; Richard, MJ1
Huwiler, A; Pfeilschifter, J1
Breuer, S; Chang, MW; Torbett, BE; Yuan, J1
Kinoshita, S; Kondo, K1
Al-Dosari, MS; Al-Mishari, AA; Almoqbil, AN; Alsaid, MS; Ghorab, MM; Ragab, FA1
Klöckl, L; Schuchardt, M; Tölle, M; van der Giet, M; Wiedon, A; Zidek, W1
Aquino, TM; Araújo-Júnior, JX; Barreto, EO; Bortoluzzi, JH; Ferreira, RS; França, PHB; Gatto, CC; Lima, MCA; Mendonça-Júnior, FJB; Meneghetti, MR; Moreira, DRM; Scotti, L; Scotti, MT; Silva, EB; Silva, EPS; Silva, JPN; Silva-Júnior, EF; Siqueira-Neto, JL1
Emoto, N; Hattori, N; Nagamine, T; Nakamura, Y; Okajima, F; Sugihara, H1
Ben-Salha, I; Costa, H; Echeverria, LMC; Freeman, A; Gately, KA; Haider, A; Heavey, S; Jameson, C; Kelly, JD; Kumar, C; Luszczak, S; Pye, H; Ratynska, M; Sathyadevan, VK; Shaw, G; Simpson, BS; Sridhar, A; Stopka-Farooqui, U; Whitaker, HC1
Mori-Anai, K; Nakada, T; Nakamaru, Y; Saito, R; Takahata, T; Tashima, Y1
Brimson, JM; Malar, DS; Prasanth, MI; Tencomnao, T1

Reviews

2 review(s) available for thiophenes and thiazolidines

ArticleYear
New players on the center stage: sphingosine 1-phosphate and its receptors as drug targets.
    Biochemical pharmacology, 2008, May-15, Volume: 75, Issue:10

    Topics: Animals; Fingolimod Hydrochloride; Humans; Lysophospholipids; Oxadiazoles; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Pyrazoles; Pyridines; Receptors, Lysosphingolipid; Sphingosine; Sulfhydryl Compounds; Thiazolidines; Thiophenes

2008
The emerging role of the sigma-1 receptor in autophagy: hand-in-hand targets for the treatment of Alzheimer's.
    Expert opinion on therapeutic targets, 2021, Volume: 25, Issue:5

    Topics: Alzheimer Disease; Animals; Autophagy; Furans; Humans; Maleates; Molecular Targeted Therapy; Receptors, sigma; Sigma-1 Receptor; Spiro Compounds; Thiazolidines; Thiophenes

2021

Trials

2 trial(s) available for thiophenes and thiazolidines

ArticleYear
Preventive effect of ipragliflozin on nocturnal hypoglycemia in patients with type 2 diabetes treated with basal-bolus insulin therapy: An open-label, single-center, parallel, randomized control study.
    Journal of diabetes investigation, 2017, Volume: 8, Issue:3

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Glucosides; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Middle Aged; Pyrazoles; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiazolidines; Thiophenes; Treatment Outcome; Young Adult

2017
Mechanistic evaluation of the effect of sodium-dependent glucose transporter 2 inhibitors on delayed glucose absorption in patients with type 2 diabetes mellitus using a quantitative systems pharmacology model of human systemic glucose dynamics.
    Biopharmaceutics & drug disposition, 2020, Volume: 41, Issue:8-9

    Topics: Adult; Benzhydryl Compounds; Blood Glucose; Canagliflozin; Diabetes Mellitus, Type 2; Female; Glucose; Glucosides; Humans; Intestinal Absorption; Kidney; Male; Middle Aged; Models, Biological; Postprandial Period; Pyrazoles; Sitagliptin Phosphate; Sodium-Glucose Transporter 2 Inhibitors; Thiazolidines; Thiophenes; Young Adult

2020

Other Studies

9 other study(ies) available for thiophenes and thiazolidines

ArticleYear
Serine proteinase inhibition by the cyclic thiolic compound YS3025: a crystallographic study.
    Biochemistry international, 1992, Volume: 28, Issue:3

    Topics: Binding Sites; Chymotrypsin; Fourier Analysis; Thiazolidines; Thiophenes; X-Ray Diffraction

1992
Inhibition of serine proteinases belonging to the chymotrypsin superfamily by the cyclic thiolic compound YS3025: a comparative crystallographic study.
    Biochemical and biophysical research communications, 1993, May-28, Volume: 193, Issue:1

    Topics: Animals; Cattle; Chymotrypsin; Pancreas; Pancreatic Elastase; Serine Proteinase Inhibitors; Substrate Specificity; Swine; Thiazolidines; Thiophenes; Trypsin; Trypsin Inhibitors; X-Ray Diffraction

1993
Thiols and selenium: protective effect on human skin fibroblasts exposed to UVA radiation.
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 40, Issue:1

    Topics: Acetylcysteine; Antioxidants; Cell Survival; Cells, Cultured; Cysteine; Dose-Response Relationship, Radiation; Female; Fibroblasts; Glutathione; Humans; Pyrrolidonecarboxylic Acid; Radiation-Protective Agents; Skin; Sodium Selenite; Surgery, Plastic; Thiazoles; Thiazolidines; Thiophenes; Ultraviolet Rays

1997
Identification of HIV-1 inhibitors targeting the nucleocapsid protein.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Anti-HIV Agents; Benzene Derivatives; Benzodioxoles; CD4-Positive T-Lymphocytes; Cell Line; Cells, Cultured; DNA, Viral; Fluorescence Polarization; Fluorometry; gag Gene Products, Human Immunodeficiency Virus; Green Fluorescent Proteins; High-Throughput Screening Assays; HIV-1; Humans; Isoxazoles; Protein Binding; Recombinant Fusion Proteins; RNA, Viral; Stereoisomerism; Structure-Activity Relationship; Thiazolidines; Thiophenes

2012
Evaluation of pharmacokinetic and pharmacodynamic interactions of canagliflozin and teneligliptin in Japanese healthy male volunteers.
    Expert opinion on drug metabolism & toxicology, 2015, Volume: 11, Issue:1

    Topics: Adult; Asian People; Canagliflozin; Cross-Over Studies; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Drug Evaluation; Drug Interactions; Glucosides; Healthy Volunteers; Humans; Male; Pyrazoles; Thiazolidines; Thiophenes; Young Adult

2015
Novel quinolines carrying pyridine, thienopyridine, isoquinoline, thiazolidine, thiazole and thiophene moieties as potential anticancer agents.
    Acta pharmaceutica (Zagreb, Croatia), 2016, Jun-01, Volume: 66, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Inhibitory Concentration 50; Isoquinolines; MCF-7 Cells; Models, Molecular; Molecular Structure; Pyridines; Quinolines; Structure-Activity Relationship; Thiazoles; Thiazolidines; Thiophenes

2016
Regulation of endothelial nitric oxide synthase activation in endothelial cells by S1P1 and S1P3.
    Biochemical and biophysical research communications, 2016, 08-05, Volume: 476, Issue:4

    Topics: Anilides; beta-Alanine; Endothelial Cells; Enzyme Activation; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Organophosphates; Organophosphonates; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Thiazolidines; Thiophenes

2016
Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi.
    Bioorganic & medicinal chemistry, 2016, 09-15, Volume: 24, Issue:18

    Topics: Animals; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Glycine; Mice; Molecular Docking Simulation; Octoxynol; Protozoan Proteins; Thiazolidines; Thiophenes; Thiourea; Trypanocidal Agents; Trypanosoma cruzi

2016
Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer.
    Scientific reports, 2020, 09-01, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Cohort Studies; Drug Therapy, Combination; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Male; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Pyridines; Pyrimidines; Quinolines; RNA, Messenger; Signal Transduction; Thiazolidines; Thiophenes; TOR Serine-Threonine Kinases

2020