thiophenes has been researched along with stf 083010 in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 19 (79.17) | 24.3611 |
| 2020's | 5 (20.83) | 2.80 |
| Authors | Studies |
|---|---|
| Bouley, DM; Denko, NC; Koong, AC; Lust, S; Niwa, M; Offner, F; Olson, M; Papandreou, I; Solow-Cordero, DE; Tam, A; Van Melckebeke, H | 1 |
| Chien, W; Ding, LW; Garg, M; Gery, S; Kitajima, S; Koeffler, PH; Lee, KL; Leong, WZ; Lim, SL; Poellinger, L; Sun, H; Sun, QY; Takao, S; Tan, SZ; Tokatly, I; Torres-Fernandez, LA; Xiao, J | 1 |
| Cruz, GL; Dickhout, JG; Mohammed-Ali, Z | 1 |
| Jiang, D; Koong, AC; Niwa, M | 1 |
| Byun, S; Chu, K; Hiraki, M; Kodama, R; Lee, SW; Mandinova, A; Namba, T; Yoon, KW | 1 |
| Fan, N; Huang, T; Meng, Q; Ming, J; Ruan, S; Tian, B; Wang, M; Ye, D | 1 |
| Han, F; Shi, Y; Zhao, W | 1 |
| Dou, HT; Gu, XW; Liang, XH; Liu, J; Liu, L; Yan, JQ; Yang, ZM; Zhao, ML | 1 |
| Frank, JA; Ke, ZJ; Luo, J; Wang, X; Xu, M | 1 |
| Che, X; Fan, P; He, Z; Jiang, D; Liang, Y; Liu, L; Sun, X; Tan, G; Xiang, X; Zhang, H; Zhao, J; Zhao, Q | 1 |
| Hogstrand, C; Luo, Z; Pan, YX; Song, YF; Wei, CC; Wu, K | 1 |
| Chen, D; Dixon, BJ; Doycheva, DM; Filippov, V; Flores, J; Guo, Z; He, Y; Hu, Q; Li, B; Nowrangi, D; Tang, J; Zhang, JH; Zhang, Y | 1 |
| Chen, H; Dong, G; Li, X; Liu, L; Shu, C; Wang, D; Wang, R; Xu, L; Zhang, S | 1 |
| Bailly-Maitre, B; Chevet, E; Hazari, Y; Hetz, C; Lebeaupin, C; Vallée, D | 1 |
| Goodrich, DW; Koochekpour, S; Shourideh, M; Wadosky, KM | 1 |
| Barbosa-Dantas, RSS; Colleoni, GWB; de Oliveira, MB; Eugenio, AIP; Sanson, LFG | 1 |
| Abe, I; Enjoji, M; Harada, Y; Horita, Y; Kobayashi, K; Nomiyama, T; Ohe, K; Tanabe, M; Tanaka, T; Yamasaki, T; Yanase, T | 1 |
| Li, X; Yang, S; Yang, W; Zhan, F; Zhang, F; Zhao, G; Zhou, S | 1 |
| Zito, E | 1 |
| Liu, A; Xiang, L; Xu, G | 1 |
| Guo, J; Lei, Y; Lei, Z; Niu, Z; Song, Q; Wu, H; Yang, J; Yang, L; Yang, Y; Zhang, X | 1 |
| Doycheva, DM; Gamdzyk, M; Hu, X; Huang, J; Liu, R; Lu, W; Tang, J; Zhang, JH | 1 |
| Hong, S; Ke, R; Wang, Y; Xiao, L | 1 |
| Fang, Q; Jin, Q; Jing, G; Liu, W; Liu, Y; Song, X; Wang, Y; Wu, X; Xia, Y; Yuan, M; Zhang, Z; Zuo, J | 1 |
4 review(s) available for thiophenes and stf 083010
| Article | Year |
|---|---|
Crosstalk between the unfolded protein response and NF-κB-mediated inflammation in the progression of chronic kidney disease.
Topics: Butylamines; Cinnamates; Disease Progression; Endoplasmic Reticulum Stress; Humans; Inflammation; Inflammation Mediators; NF-kappa B; Proteinuria; Renal Insufficiency, Chronic; Signal Transduction; Sulfonamides; Sulfones; Thiophenes; Thiourea; Unfolded Protein Response | 2015 |
Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases.
Topics: Aldehydes; Animals; Apoptosis; Cell Survival; Coumarins; Disease Models, Animal; Disease Progression; DNA-Binding Proteins; Drug Design; Drug Discovery; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Endoribonucleases; Homeostasis; Humans; Mice; Neoplasms; Neurodegenerative Diseases; Prognosis; Protein Folding; Protein Serine-Threonine Kinases; Quercetin; Regulatory Factor X Transcription Factors; Signal Transduction; Sulfonamides; Thiophenes; Toyocamycin; Transcription Factors; Unfolded Protein Response; X-Box Binding Protein 1 | 2015 |
Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease.
Topics: Activating Transcription Factor 6; Animals; Autophagy; Calcium; Endoplasmic Reticulum Stress; Genetic Therapy; Humans; Insulin Resistance; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Signal Transduction; Sulfonamides; Thiophenes; Unfolded Protein Response | 2018 |
Targeting ER stress/ER stress response in myopathies.
Topics: Activating Transcription Factor 6; Adenine; Aldehydes; Animals; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Endoribonucleases; Gene Expression Regulation; Humans; Indoles; Mice; Mitochondria; Molecular Targeted Therapy; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Diseases; Phenylbutyrates; Protein Serine-Threonine Kinases; Signal Transduction; Sulfonamides; Thiophenes | 2019 |
20 other study(ies) available for thiophenes and stf 083010
| Article | Year |
|---|---|
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cells, Cultured; Cytotoxins; Dose-Response Relationship, Drug; Endoribonucleases; Humans; Mice; Models, Biological; Multiple Myeloma; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrazines; Substrate Specificity; Sulfonamides; Thiophenes; Xenograft Model Antitumor Assays | 2011 |
Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells.
Topics: Animals; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; DNA-Binding Proteins; Drug Synergism; Endoribonucleases; Enzyme Inhibitors; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice, Inbred NOD; Mice, SCID; Naphthalenes; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Pyrazines; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA Splicing; Sulfonamides; Thiophenes; Toyocamycin; Transcription Factors; Unfolded Protein Response; X-Box Binding Protein 1; Xenograft Model Antitumor Assays | 2014 |
Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.
Topics: Animals; Cell Line, Tumor; DNA-Binding Proteins; Endoplasmic Reticulum; Endoribonucleases; HCT116 Cells; Heterografts; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Regulatory Factor X Transcription Factors; Signal Transduction; Sulfonamides; Thiophenes; Transcription Factors; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; X-Box Binding Protein 1 | 2015 |
A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Proliferation; DNA-Binding Proteins; Drug Resistance, Neoplasm; Endoribonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Grading; Neoplasm Staging; Prognosis; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Survival Rate; Tamoxifen; Thiophenes; Transcription Factors; Tumor Cells, Cultured; Unfolded Protein Response; X-Box Binding Protein 1; Xenograft Model Antitumor Assays | 2015 |
IRE1α pathway of endoplasmic reticulum stress induces neuronal apoptosis in the locus coeruleus of rats under single prolonged stress.
Topics: Animals; Apoptosis; Disease Models, Animal; Endoplasmic Reticulum Stress; Endoribonucleases; Enzyme Inhibitors; Heat-Shock Proteins; Locus Coeruleus; Male; Multienzyme Complexes; Neurons; Protein Serine-Threonine Kinases; Random Allocation; Rats, Wistar; Signal Transduction; Stress Disorders, Post-Traumatic; Sulfonamides; Thiophenes; Transcription Factor CHOP; X-Box Binding Protein 1 | 2016 |
Endoplasmic reticulum stress in mouse decidua during early pregnancy.
Topics: Animals; Cell Proliferation; Decidua; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endoribonucleases; Female; Heat-Shock Proteins; Mice; Pregnancy; Protein Serine-Threonine Kinases; Signal Transduction; Stromal Cells; Sulfonamides; Taurochenodeoxycholic Acid; Thiophenes; Tunicamycin; Unfolded Protein Response; X-Box Binding Protein 1 | 2016 |
Thiamine deficiency induces endoplasmic reticulum stress and oxidative stress in human neurons derived from induced pluripotent stem cells.
Topics: Antioxidants; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Induced Pluripotent Stem Cells; Neurons; Oxidative Stress; Sulfonamides; Thiamine Deficiency; Thiophenes | 2017 |
Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage.
Topics: Adenine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blood-Brain Barrier; Brain Edema; Carrier Proteins; Cell Cycle Proteins; Encephalitis; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Gene Expression Regulation; Indoles; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Subarachnoid Hemorrhage; Sulfonamides; Thiophenes | 2017 |
Endoplasmic reticulum (ER) stress and cAMP/PKA pathway mediated Zn-induced hepatic lipolysis.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Catfishes; Down-Regulation; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Hazardous Substances; Homeostasis; Lipid Metabolism; Lipolysis; Liver; Signal Transduction; Sulfonamides; Thiophenes; Zinc | 2017 |
IRE1α inhibition decreased TXNIP/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic-ischemic brain injury in rats.
Topics: Administration, Intranasal; Animals; Animals, Newborn; Carrier Proteins; Cell Cycle Proteins; Endoribonucleases; Hypoxia-Ischemia, Brain; Inflammasomes; MicroRNAs; Multienzyme Complexes; NLR Family, Pyrin Domain-Containing 3 Protein; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes | 2018 |
STF-083010, an inhibitor of XBP1 splicing, attenuates acute renal failure in rats by suppressing endoplasmic reticulum stress-induced apoptosis and inflammation.
Topics: Acute Kidney Injury; Animals; Apoptosis; Depression, Chemical; Endoplasmic Reticulum Stress; Inflammation; Male; Molecular Targeted Therapy; Protein Splicing; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; X-Box Binding Protein 1 | 2018 |
Riluzole induces AR degradation via endoplasmic reticulum stress pathway in androgen-dependent and castration-resistant prostate cancer cells.
Topics: Activating Transcription Factor 6; Androgens; Autophagy; Cell Line, Tumor; Drug Interactions; Endoplasmic Reticulum Stress; Endoribonucleases; Humans; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein Serine-Threonine Kinases; Receptors, Androgen; Riluzole; Sequestosome-1 Protein; Signal Transduction; Sulfonamides; Thiophenes | 2019 |
Stew in its Own Juice: Protein Homeostasis Machinery Inhibition Reduces Cell Viability in Multiple Myeloma Cell Lines.
Topics: Apoptosis; Autophagy; Benzamides; Bortezomib; Cell Survival; Drug Synergism; HSP70 Heat-Shock Proteins; Humans; Multiple Myeloma; Proteasome Inhibitors; Proteostasis; Pyrimidines; Sulfonamides; Thiophenes; Tumor Cells, Cultured; Unfolded Protein Response | 2019 |
Circular IRE-type RNAs of the NR5A1 gene are formed in adrenocortical cells.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Base Sequence; Binding Sites; Cell Line, Tumor; Endoplasmic Reticulum Stress; Endoribonucleases; Exons; Gene Expression; Humans; Models, Biological; Protein Serine-Threonine Kinases; RNA Splicing; RNA, Circular; RNA, Messenger; Steroidogenic Factor 1; Sulfonamides; Thiophenes | 2019 |
Inositol-requiring enzyme 1 alpha endoribonuclease specific inhibitor STF-083010 protects the liver from thioacetamide-induced oxidative stress, inflammation and injury by triggering hepatocyte autophagy.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Autophagy; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytokines; Endoribonucleases; Hepatocytes; Male; Mice, Inbred C57BL; Oxidative Stress; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Sulfonamides; Thioacetamide; Thiophenes | 2019 |
Expression of XBP1s in B lymphocytes is critical for pristane-induced lupus nephritis in mice.
Topics: Animals; Autoantibodies; B-Lymphocytes; Cell Proliferation; Disease Models, Animal; Female; Immunoglobulin G; Kidney; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphocyte Activation; Mice, Inbred BALB C; Signal Transduction; Spleen; Sulfonamides; Terpenes; Thiophenes; X-Box Binding Protein 1 | 2020 |
Activation of Wnt/β-catenin pathway causes insulin resistance and increases lipogenesis in HepG2 cells via regulation of endoplasmic reticulum stress.
Topics: Activating Transcription Factors; beta Catenin; Down-Regulation; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endoribonucleases; Eukaryotic Initiation Factor-2; Heat-Shock Proteins; Hep G2 Cells; Hepatocytes; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipogenesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Sulfonamides; Thiophenes; Transcription Factor CHOP; Wnt Proteins; Wnt Signaling Pathway | 2020 |
IRE1α inhibition attenuates neuronal pyroptosis via miR-125/NLRP1 pathway in a neonatal hypoxic-ischemic encephalopathy rat model.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Endoribonucleases; Hypoxia-Ischemia, Brain; Inflammasomes; MicroRNAs; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Protein Serine-Threonine Kinases; Pyroptosis; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Thiophenes | 2020 |
Endoplasmic reticulum stress related factor IRE1α regulates TXNIP/NLRP3-mediated pyroptosis in diabetic nephropathy.
Topics: Animals; Cell Cycle Proteins; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Endoplasmic Reticulum Stress; Endoribonucleases; Glucose; Kidney Tubules; Male; MicroRNAs; Models, Biological; Multienzyme Complexes; NLR Family, Pyrin Domain-Containing 3 Protein; Protein Serine-Threonine Kinases; Pyroptosis; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Up-Regulation | 2020 |
Erbin protects against sepsis-associated encephalopathy by attenuating microglia pyroptosis via IRE1α/Xbp1s-Ca
Topics: Animals; Cytokines; Endoribonucleases; Lipopolysaccharides; Mice; Mice, Knockout; Microglia; Nigericin; Protein Serine-Threonine Kinases; Pyroptosis; Sepsis-Associated Encephalopathy; Sulfonamides; Thiophenes | 2022 |