thiophenes has been researched along with squalene in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Fukuzumi, H; Horie, M; Iizuka, Y; Kamei, T; Sawasaki, Y; Tsuchiya, Y; Watanabe, K | 1 |
| Fukuzumi, H; Hayashi, M; Horie, M; Iida, Y; Iwasawa, Y; Kamei, T; Kitani, K; Nagata, Y; Sawasaki, Y; Tsuchiya, Y | 1 |
| Kamei, T; Nagumo, A; Ono, T; Sakakibara, J | 1 |
| Fisher, PL; Fliesler, SJ; Keller, PK; Pittler, SJ; Rapp, LM | 1 |
| Hayashi, M; Horie, M; Hotta, H; Ishida, F; Kamei, T; Nagata, Y; Satoh, T | 1 |
| Alvarez, G; Benítez, D; Boiani, L; Cerecetto, H; Gerpe, A; González, M; Hernández, P; Quiroga, M; Sortino, M; Zacchino, S | 1 |
| Brown, AJ; Chua, NK; Coates, HW; Hashimoto, Y; Ohgane, K; Yoshioka, H | 1 |
7 other study(ies) available for thiophenes and squalene
| Article | Year |
|---|---|
Hypolipidemic effects of NB-598 in dogs.
Topics: Animals; Anticholesteremic Agents; Benzylamines; Bile; Bile Acids and Salts; Cholesterol; Dogs; Feces; Lipids; Lipoproteins; Lovastatin; Male; Oxygenases; Phospholipids; Simvastatin; Squalene; Squalene Monooxygenase; Thiophenes; Triglycerides | 1991 |
NB-598: a potent competitive inhibitor of squalene epoxidase.
Topics: Animals; Anticholesteremic Agents; Benzylamines; Cattle; Cell Line; Cholesterol; Humans; In Vitro Techniques; Kinetics; Lipid Metabolism; Oxygenases; Rats; Squalene; Squalene Monooxygenase; Thiophenes | 1990 |
Purification and characterization of recombinant squalene epoxidase.
Topics: Animals; Base Sequence; Benzylamines; Chromatography; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Female; Gene Expression; Hydrogen-Ion Concentration; Microsomes, Liver; Molecular Sequence Data; NADPH-Ferrihemoprotein Reductase; Octoxynol; Oxygenases; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Squalene; Squalene Monooxygenase; Thiophenes | 1995 |
In vivo requirement of protein prenylation for maintenance of retinal cytoarchitecture and photoreceptor structure.
Topics: Acetates; Acetylcysteine; Animals; Benzylamines; Cell Nucleus; Cholesterol; Female; Lipids; Lovastatin; Photoreceptor Cells; Protein Prenylation; Rats; Retina; Squalene; Sterols; Thiophenes | 1995 |
An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells.
Topics: Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Benzylamines; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Lovastatin; Oxygenases; Simvastatin; Squalene; Squalene Monooxygenase; Thiophenes; Triglycerides; Tumor Cells, Cultured | 1993 |
5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene.
Topics: Animals; Chagas Disease; Drug Design; Humans; Mice; Nitrofurans; Quantitative Structure-Activity Relationship; Squalene; Squalene Monooxygenase; Thiophenes; Trypanocidal Agents; Trypanosoma cruzi | 2009 |
A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate.
Topics: Allosteric Regulation; Benzylamines; Cholesterol; Endoplasmic Reticulum; HEK293 Cells; Humans; Membrane Proteins; Proteostasis; Squalene; Squalene Monooxygenase; Thiophenes; Ubiquitin-Protein Ligases; Ubiquitination | 2020 |