Page last updated: 2024-08-18

thiophenes and simvastatin

thiophenes has been researched along with simvastatin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (54.55)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Eda, T; Hidaka, Y; Kamei, T; Yonemoto, M1
Hidaka, Y; Horie, M; Hotta, H; Iwasawa, Y; Kamei, T; Nagata, Y1
Fukuzumi, H; Horie, M; Iizuka, Y; Kamei, T; Sawasaki, Y; Tsuchiya, Y; Watanabe, K1
Horie, M; Iwasawa, Y; Kamei, T; Nagata, Y; Satoh, T; Shimizu, A1
Hayashi, M; Horie, M; Hotta, H; Ishida, F; Kamei, T; Nagata, Y; Satoh, T1
Gohda, M; Hanasaki, Y; Ishida, N; Itoh, H; Katsuura, K; Matzno, S; Nakamura, N; Tokunaga, T; Yamauchi, T1
Meunier, PJ1
Archer, SL; Michelakis, ED1
Callaghan, JT; Duke, JD; Flockhart, DA; Hall, SD; Han, X; Jin, Y; Karnik, SD; Li, L; Li, X; Overhage, MJ; Quinney, SK; Strother, RM; Subhadarshini, A; Wang, Z1
Droździk, M; Kurzawski, M; Machaliński, B; Niedzielski, A; Pius-Sadowska, E; Wajda, A; Łapczuk-Romańska, J1
Fervers, F; Henrich, D; Kontradowitz, K; Leiblein, M; Marzi, I; Seebach, C1

Reviews

2 review(s) available for thiophenes and simvastatin

ArticleYear
Anabolic agents for treating postmenopausal osteoporosis.
    Joint bone spine, 2001, Volume: 68, Issue:6

    Topics: Animals; Controlled Clinical Trials as Topic; Female; Fluorides; Fractures, Spontaneous; Growth Hormone; Humans; Insulin-Like Growth Factor I; Organometallic Compounds; Osteoporosis, Postmenopausal; Parathyroid Hormone; Simvastatin; Thiophenes

2001
An evidence-based approach to the management of pulmonary arterial hypertension.
    Current opinion in cardiology, 2006, Volume: 21, Issue:4

    Topics: Antihypertensive Agents; Benzamides; Bosentan; Calcium Channel Blockers; Comorbidity; Dichloroacetic Acid; Drug Therapy, Combination; Epoprostenol; Evidence-Based Medicine; Fluoxetine; Humans; Hypertension, Pulmonary; Iloprost; Imatinib Mesylate; Isoxazoles; Phosphodiesterase Inhibitors; Piperazines; Prostaglandins, Synthetic; Pulmonary Artery; Purines; Pyrimidines; Randomized Controlled Trials as Topic; Sildenafil Citrate; Simvastatin; Sulfonamides; Sulfones; Thiophenes; Vasodilator Agents

2006

Other Studies

9 other study(ies) available for thiophenes and simvastatin

ArticleYear
Inhibition of cultured vascular smooth muscle cell migration by simvastatin (MK-733).
    Atherosclerosis, 1992, Volume: 95, Issue:1

    Topics: Animals; Anticholesteremic Agents; Aorta, Thoracic; Benzylamines; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Fibrinogen; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Lovastatin; Mevalonic Acid; Muscle, Smooth, Vascular; Nifedipine; Platelet-Derived Growth Factor; Pravastatin; Simvastatin; Sterols; Swine; Thiophenes

1992
Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells.
    The Journal of biological chemistry, 1991, Jul-15, Volume: 266, Issue:20

    Topics: Acetates; Anticholesteremic Agents; Benzylamines; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Cycloheximide; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Mevalonic Acid; Nucleic Acid Hybridization; Oxygenases; RNA, Neoplasm; Simvastatin; Squalene Monooxygenase; Thiophenes

1991
Hypolipidemic effects of NB-598 in dogs.
    Atherosclerosis, 1991, Volume: 88, Issue:2-3

    Topics: Animals; Anticholesteremic Agents; Benzylamines; Bile; Bile Acids and Salts; Cholesterol; Dogs; Feces; Lipids; Lipoproteins; Lovastatin; Male; Oxygenases; Phospholipids; Simvastatin; Squalene; Squalene Monooxygenase; Thiophenes; Triglycerides

1991
Effects of NB-598, a potent squalene epoxidase inhibitor, on the apical membrane uptake of cholesterol and basolateral membrane secretion of lipids in Caco-2 cells.
    Biochemical pharmacology, 1993, Jul-20, Volume: 46, Issue:2

    Topics: Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Benzylamines; Cell Line; Cell Membrane; Cholesterol; Cholesterol Esters; Enzyme Activation; Humans; Linoleic Acids; Lipids; Lovastatin; Microsomes; Oleic Acid; Oleic Acids; Oxygenases; Polyunsaturated Alkamides; Simvastatin; Squalene Monooxygenase; Sterol O-Acyltransferase; Thiophenes; Tritium; Tumor Cells, Cultured

1993
An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells.
    Biochimica et biophysica acta, 1993, May-20, Volume: 1168, Issue:1

    Topics: Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Benzylamines; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Lovastatin; Oxygenases; Simvastatin; Squalene; Squalene Monooxygenase; Thiophenes; Triglycerides; Tumor Cells, Cultured

1993
Inhibition of cholesterol biosynthesis by squalene epoxidase inhibitor avoids apoptotic cell death in L6 myoblasts.
    Journal of lipid research, 1997, Volume: 38, Issue:8

    Topics: Actins; Animals; Apoptosis; Benzylamines; Cell Differentiation; Cell Line; Cholesterol; DNA Fragmentation; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Fibers, Skeletal; Oxygenases; Rats; Simvastatin; Squalene Monooxygenase; Thiophenes

1997
Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions.
    PLoS computational biology, 2012, Volume: 8, Issue:8

    Topics: Alprazolam; Databases, Factual; Drug Interactions; Duloxetine Hydrochloride; Electronic Health Records; Humans; Indoles; Loratadine; Muscular Diseases; Promethazine; Simvastatin; Thiophenes

2012
Effects of simvastatin on nuclear receptors, drug metabolizing enzymes and transporters expression in Human Umbilical Vein Endothelial Cells.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:5

    Topics: ATP Binding Cassette Transporter, Subfamily B; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Peroxisome-Targeting Signal 1 Receptor; Polychlorinated Dibenzodioxins; Pyrazines; Receptors, Aryl Hydrocarbon; Simvastatin; Thiones; Thiophenes

2018
Do antiosteoporotic drugs improve bone regeneration in vivo?
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2020, Volume: 46, Issue:2

    Topics: Absorptiometry, Photon; Alendronate; Alkaline Phosphatase; Animals; Biomechanical Phenomena; Blotting, Western; Bone Density; Bone Density Conservation Agents; Bone Morphogenetic Protein 2; Bone Regeneration; Bony Callus; Calcium-Regulating Hormones and Agents; Collagen Type I; Female; Femur; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Macrophage Colony-Stimulating Factor; Osteocalcin; Osteogenesis; Osteogenesis, Distraction; Parathyroid Hormone; Raloxifene Hydrochloride; RANK Ligand; Rats; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Thiophenes; Tomography, X-Ray Computed

2020