thiophenes has been researched along with sb 271046 in 42 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (2.38) | 18.2507 |
2000's | 26 (61.90) | 29.6817 |
2010's | 13 (30.95) | 24.3611 |
2020's | 2 (4.76) | 2.80 |
Authors | Studies |
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Bromidge, SM; Brown, AM; Clarke, SE; Dodgson, K; Gager, T; Grassam, HL; Jeffrey, PM; Joiner, GF; King, FD; Middlemiss, DN; Moss, SF; Newman, H; Riley, G; Routledge, C; Wyman, P | 1 |
Dawson, LA; Li, P; Nguyen, HQ | 3 |
Bromidge, SM; Brown, AM; Clarke, SE; Gager, T; Hirst, W; Middlemiss, DN; Moss, SF; Newman, H; Price, GW; Riley, G; Routledge, C; Stean, T; Upton, N | 1 |
Miguel-Hidalgo, JJ | 1 |
Hagan, JJ; Rogers, DC | 1 |
Arnt, J; Didriksen, M; Pouzet, B | 1 |
Dawson, LA; Li, P | 1 |
Barten, DM; Corsa, JA; Gillman, KW; Gribkoff, VK; Guss, VL; Hodges, DB; Hogan, JB; Lindner, MD; Orie, AF; Polson, C; Robertson, BJ; Starrett, JE | 1 |
Foley, AG; Gallagher, HC; Hagan, JJ; Hirst, WD; Murphy, KJ; Regan, CM; Upton, N; Walsh, FS | 1 |
Dawson, LA; Hagan, JJ; Heidbreder, CA; Lacroix, LP | 1 |
Ashby, CR; Hagan, JJ; Hashimoto, K; Minabe, Y; Routledge, C; Shirayama, Y | 1 |
Fone, KC; King, MV; Marsden, CA; Sleight, AJ; Topham, IA; Woolley, ML | 1 |
Bate, S; Brown, VJ; Hagan, JJ; Hatcher, PD; Jones, DN; Overend, P; Tait, DS | 1 |
Buschmann, H; Codony, X; Dordal, A; Fisas, A; Giraldo, J; Heal, D; Holenz, J; Mercé, R; Pauwels, PJ; Romero, G; Sørensen, RV; Vrang, N | 1 |
Beyer, CE; Hughes, ZA; Kerns, EH; Lin, Q; Zhang, MY | 1 |
de Foubert, G; O'Neill, MJ; Zetterström, TS | 1 |
Cilia, J; Hatcher, P; Jones, DN; Reavill, C | 1 |
Ansell, L; Baxter, JA; Beckett, SR; Chapman, V; Finn, DP; Fone, KC; Marsden, CA | 1 |
Dekeyne, A; Loiseau, F; Millan, MJ | 1 |
Aisa, B; Marcos, B; Ramírez, MJ | 1 |
Barry, C; Foley, AG; Gallagher, HC; Hagan, JJ; Hirst, WD; Hunter, AJ; Regan, CM; Upton, N; Walsh, FS | 1 |
Boulouard, M; Da Silva Costa, V; Dauphin, F; Duchatelle, P | 1 |
Chuang, TT; Gil-Bea, FJ; Marcos, B; Ramirez, MJ | 1 |
Chapman, PF; Hirano, K; Miller, ND; Piers, TM; Rutter, AR; Searle, KL | 1 |
Aisa, B; Chuang, TT; Gil-Bea, FJ; Marcos, B; Ramírez, MJ | 1 |
Aisa, B; Cabero, M; Marcos, B; Ramirez, MJ; Solas, M | 1 |
De Vries, TJ; Schetters, D; Schoffelmeer, AN; van Gaalen, MM | 1 |
Bordi, F; Borsini, F; Di Chiara, G; Frau, R; Valentini, V | 1 |
de Bruin, NM; Kloeze, BM; McCreary, AC | 1 |
Boulouard, M; Da Silva Costa-Aze, V; Dauphin, F | 1 |
Boulouard, M; Da Silva Costa-Aze, V; Dauphin, F; Quiedeville, A | 1 |
Clarke, NN; Fone, KC; Layfield, R; Woods, S | 1 |
Fijał, K; Nikiforuk, A; Popik, P | 1 |
Bouet, V; Boulouard, M; Da Silva Costa-Aze, V; Dallemagne, P; Fabis, F; Freret, T; Hamidouche, K; Nee, G; Quiedeville, A; Rochais, C | 1 |
Asselot, R; Bouet, V; Dauphin, F; Delaunay, V; Duchatelle, P; Lebourgeois, S; Nee, G; Simon-O'Brien, E | 1 |
Briones-Aranda, A; Espinosa-Raya, J; Picazo, O; Suárez-Santiago, JE | 1 |
Geng, F; Lu, GF; Luo, Y; Peng, C; Tian, J; Wu, JL; Zou, WJ | 1 |
Chen, XF; Gong, Y; Jin, ZL; Li, YF; Ran, YH; Wang, XY; Zhang, LM; Zhang, YZ; Zhao, N | 1 |
Picazo Picazo, O; Roldán Roldán, G; Suárez-Santiago, JE | 1 |
Billard, JM; Bouet, V; Freret, T; Lahogue, C | 1 |
42 other study(ies) available for thiophenes and sb 271046
Article | Year |
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5-Chloro-N-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): a potent, selective, and orally bioavailable 5-HT6 receptor antagonist.
Topics: Administration, Oral; Animals; Biological Availability; Cell Line; Humans; Rats; Receptors, Serotonin; Serotonin Antagonists; Sulfonamides; Thiophenes | 1999 |
In vivo effects of the 5-HT(6) antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate.
Topics: Animals; Biogenic Monoamines; Corpus Striatum; Excitatory Amino Acids; Frontal Lobe; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Sulfonamides; Thiophenes | 2000 |
Characterization of SB-271046: a potent, selective and orally active 5-HT(6) receptor antagonist.
Topics: Adenylyl Cyclases; Administration, Oral; Animals; Binding, Competitive; Brain; Cognition; Disease Models, Animal; Electric Stimulation; HeLa Cells; Humans; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Recombinant Proteins; Seizures; Serotonin Antagonists; Sulfonamides; Thiophenes; Transfection | 2000 |
SB-271046 (SmithKline Beecham).
Topics: Animals; Humans; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides; Thiophenes | 2001 |
The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus.
Topics: Animals; Atropine; Dopamine; Excitatory Amino Acids; Extracellular Space; Glutamic Acid; Hippocampus; Male; Microdialysis; Muscarinic Antagonists; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sulfonamides; Synaptic Transmission; Tetrodotoxin; Thiophenes | 2001 |
5-HT6 receptor antagonists enhance retention of a water maze task in the rat.
Topics: Animals; Male; Maze Learning; Piperazines; Rats; Receptors, Serotonin; Retention, Psychology; Serotonin Antagonists; Sulfonamides; Swimming; Thiophenes | 2001 |
Effects of the 5-HT(6) receptor antagonist, SB-271046, in animal models for schizophrenia.
Topics: Animals; Catalepsy; Central Nervous System Stimulants; Clozapine; Dextroamphetamine; Dose-Response Relationship, Drug; Hyperkinesis; Male; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Startle; Schizophrenia; Serotonin Antagonists; Social Behavior; Sulfonamides; Thiophenes | 2002 |
Potentiation of amphetamine-induced changes in dopamine and 5-HT by a 5-HT(6) receptor antagonist.
Topics: Amphetamine; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Drug Synergism; Extracellular Space; Glutamic Acid; Male; Microdialysis; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sulfonamides; Thiophenes | 2003 |
Effects of 5-HT(6) receptor blockade on the neurochemical outcome of antidepressant treatment in the frontal cortex of the rat.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Cyclohexanols; Depressive Disorder; Desipramine; Drug Synergism; Extracellular Space; Fluoxetine; Glutamic Acid; Male; Microdialysis; Neurons; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sulfonamides; Synaptic Transmission; Thiophenes; Venlafaxine Hydrochloride | 2003 |
An assessment of the effects of serotonin 6 (5-HT6) receptor antagonists in rodent models of learning.
Topics: Animals; Binding Sites; Humans; Learning; Mastication; Mice; Models, Animal; Pyrimidines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Sulfonamides; Thiophenes; Yawning | 2003 |
The 5-HT(6) receptor antagonist SB-271046 reverses scopolamine-disrupted consolidation of a passive avoidance task and ameliorates spatial task deficits in aged rats.
Topics: Administration, Oral; Aging; Amnesia; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Locomotion; Male; Maze Learning; Memory; Rats; Rats, Wistar; Reaction Time; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Spatial Behavior; Sulfonamides; Swimming; Thiophenes | 2004 |
5-HT6 receptor antagonist SB-271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex.
Topics: Analysis of Variance; Animals; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Extracellular Space; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Sulfonamides; Thiophenes; Time Factors | 2004 |
Effect of the acute and chronic administration of the selective 5-HT6 receptor antagonist SB-271046 on the activity of midbrain dopamine neurons in rats: an in vivo electrophysiological study.
Topics: Action Potentials; Animals; Cell Count; Clozapine; Dopamine; Electrophysiology; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Substantia Nigra; Sulfonamides; Thiophenes; Ventral Tegmental Area | 2004 |
5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation--an effect sensitive to NMDA receptor antagonism.
Topics: Animals; Cognition; Discrimination, Psychological; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Pyrimidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Antagonists; Sulfonamides; Synaptic Transmission; Thiophenes | 2004 |
5-HT6 receptor antagonists improve performance in an attentional set shifting task in rats.
Topics: Administration, Oral; Animals; Attention; Intelligence Tests; Male; Piperazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Sulfonamides; Task Performance and Analysis; Thiophenes; Time Factors | 2005 |
Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats.
Topics: Animals; Anti-Obesity Agents; Appetite Depressants; Blood Glucose; Body Weight; Cell Line; Conditioning, Operant; Cyclic AMP; Cyclobutanes; Diet; Drinking; Eating; Feeding Behavior; Female; Humans; In Vitro Techniques; Indoles; Lipids; Male; Motor Activity; Obesity; Rats; Receptors, Serotonin; Serotonin; Sulfonamides; Taste; Thiophenes; Weight Loss | 2006 |
Development of a liquid chromatography/tandem mass spectrometry method for the quantitation of acetylcholine and related neurotransmitters in brain microdialysis samples.
Topics: Acetylcholine; Animals; Brain Chemistry; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Donepezil; Hippocampus; Indans; Indicators and Reagents; Male; Microdialysis; Neurotransmitter Agents; Piperidines; Rats; Receptors, Serotonin; Reference Standards; Reproducibility of Results; Serotonin Antagonists; Sodium Channel Blockers; Spectrometry, Mass, Electrospray Ionization; Stereotaxic Techniques; Sulfonamides; Tetrodotoxin; Thiophenes | 2007 |
Acute onset by 5-HT(6)-receptor activation on rat brain brain-derived neurotrophic factor and activity-regulated cytoskeletal-associated protein mRNA expression.
Topics: Animals; Autoradiography; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Hippocampus; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Thiophenes | 2007 |
(+/-) Ketamine-induced prepulse inhibition deficits of an acoustic startle response in rats are not reversed by antipsychotics.
Topics: Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Ketamine; Lamotrigine; Male; Pyridines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Risperidone; Schizophrenia; Sulfonamides; Thiophenes; Triazines | 2007 |
The effects of pharmacological blockade of the 5-HT(6) receptor on formalin-evoked nociceptive behaviour, locomotor activity and hypothalamo-pituitary-adrenal axis activity in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Defecation; Dose-Response Relationship, Drug; Formaldehyde; Grooming; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Male; Motor Activity; Pain; Pain Measurement; Pituitary-Adrenal System; Radioimmunoassay; Rats; Receptors, Serotonin; Serotonin Antagonists; Stress, Physiological; Sulfonamides; Thiophenes; Time Factors | 2007 |
Pro-cognitive effects of 5-HT6 receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex.
Topics: Animals; Basal Nucleus of Meynert; Corpus Striatum; Dose-Response Relationship, Drug; Frontal Lobe; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mental Recall; Microinjections; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Social Behavior; Sulfonamides; Thiophenes | 2008 |
Functional interaction between 5-HT(6) receptors and hypothalamic-pituitary-adrenal axis: cognitive implications.
Topics: Acetates; Adrenalectomy; Animals; Behavior, Animal; Cognition; Corticosterone; Corticotropin-Releasing Hormone; Drug Interactions; Frontal Lobe; Hippocampus; Hypothalamo-Hypophyseal System; Male; Maternal Deprivation; Morpholines; Neuropsychological Tests; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sulfonamides; Thiophenes | 2008 |
The selective 5-HT6 receptor antagonists SB-271046 and SB-399885 potentiate NCAM PSA immunolabeling of dentate granule cells, but not neurogenesis, in the hippocampal formation of mature Wistar rats.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cell Proliferation; Cytoplasmic Granules; Dentate Gyrus; Dose-Response Relationship, Drug; Entorhinal Cortex; Hippocampus; Immunohistochemistry; Male; Maze Learning; Neural Cell Adhesion Molecules; Neurons; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Sialic Acids; Sulfonamides; Thiophenes | 2008 |
Selective 5-HT6 receptor blockade improves spatial recognition memory and reverses age-related deficits in spatial recognition memory in the mouse.
Topics: Aging; Analysis of Variance; Animals; Exploratory Behavior; Female; Male; Maze Learning; Mice; Motor Activity; Receptors, Serotonin; Recognition, Psychology; Serotonin Antagonists; Sulfonamides; Thiophenes | 2009 |
Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat.
Topics: Animals; Cholinesterase Inhibitors; Cognition Disorders; Disease Models, Animal; Dizocilpine Maleate; Drug Administration Schedule; Drug Therapy, Combination; Galantamine; Male; Maze Learning; Motor Activity; Rats; Rats, Wistar; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Sulfonamides; Thiophenes; Yawning | 2008 |
Procognitive 5-HT6 antagonists in the rat forced swimming test: potential therapeutic utility in mood disorders associated with Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Cognition; Male; Mood Disorders; Piperazines; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Sulfonamides; Swimming; Thiophenes | 2009 |
Effects of chronic blockade of 5-HT(6) receptors on NMDA receptor subunits expression.
Topics: Animals; Binding, Competitive; Brain; Drug Administration Schedule; Male; Protein Subunits; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Sulfonamides; Synaptic Transmission; Thiophenes | 2009 |
Signalling pathways associated with 5-HT6 receptors: relevance for cognitive effects.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Autoradiography; Cognition; CREB-Binding Protein; Drug Interactions; Gene Expression Regulation; Iodine Isotopes; Male; Maze Learning; Piperazines; Protein Binding; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Signal Transduction; Sulfonamides; Thiophenes | 2010 |
5-HT6 antagonism attenuates cue-induced relapse to cocaine seeking without affecting cocaine reinforcement.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Male; Pyrimidines; Random Allocation; Rats; Rats, Wistar; Receptors, Serotonin; Recurrence; Reinforcement, Psychology; Serotonin Antagonists; Sulfonamides; Thiophenes | 2010 |
A microdialysis study of ST1936, a novel 5-HT6 receptor agonist.
Topics: Analysis of Variance; Animals; Dopamine; Dose-Response Relationship, Drug; Ethylamines; Indoles; Male; Microdialysis; Norepinephrine; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Thiophenes | 2011 |
The 5-HT₆ serotonin receptor antagonist SB-271046 attenuates the development and expression of nicotine-induced locomotor sensitisation in Wistar rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Male; Motor Activity; Nicotine; Rats; Rats, Wistar; Receptors, Serotonin; Secondary Prevention; Serotonin Antagonists; Substance Withdrawal Syndrome; Substance-Related Disorders; Sulfonamides; Thiophenes; Time Factors | 2011 |
Serotonin 5-HT6 receptor blockade reverses the age-related deficits of recognition memory and working memory in mice.
Topics: Age Factors; Analysis of Variance; Animals; Exploratory Behavior; Female; Memory Disorders; Memory, Short-Term; Mice; Neuropsychological Tests; Reaction Time; Receptors, Serotonin; Recognition, Psychology; Serotonin Antagonists; Sulfonamides; Thiophenes | 2011 |
5-HT6 receptor blockade differentially affects scopolamine-induced deficits of working memory, recognition memory and aversive learning in mice.
Topics: Animals; Avoidance Learning; Cholinergic Antagonists; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Memory Disorders; Memory, Short-Term; Mice; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Sulfonamides; Thiophenes | 2012 |
5-HT(6) receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms.
Topics: Animals; Conditioning, Psychological; Dizocilpine Maleate; Electric Stimulation; Emotions; Indoles; Learning; Male; Pyridines; Rats; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Thiazoles; Thiophenes | 2012 |
Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Data Interpretation, Statistical; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Haloperidol; Male; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reflex, Startle; Risperidone; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Sulfonamides; Thiophenes | 2014 |
Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances.
Topics: Analysis of Variance; Aniline Compounds; Animals; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Memory; Mice; Motor Activity; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Sulfonamides; Thiophenes; Time Factors | 2015 |
Time-dependent impact of glutamatergic modulators on the promnesiant effect of 5-HT
Topics: Animals; Glutamic Acid; Male; Memory; Mice; Motor Activity; Pipecolic Acids; Receptors, Serotonin; Serotonin Antagonists; Sulfonamides; Thiophenes; Time Factors | 2017 |
Agonist E-6837 and antagonist SB-271046 of 5-HT6 receptors both reverse the depressive-like effect induced in mice by subchronic ketamine administration.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Depression; Depressive Disorder, Major; Disease Models, Animal; Hindlimb Suspension; Indoles; Ketamine; Male; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Schizophrenia; Sulfonamides; Swimming; Thiophenes | 2017 |
Dorsomedial prefrontal cortex 5-HT6 receptors regulate anxiety-like behavior.
Topics: Animals; Anxiety; Behavior; Indoles; Male; Mice, Inbred C57BL; Prefrontal Cortex; Pyridines; Receptors, Serotonin; Sulfonamides; Synaptic Transmission; Thiophenes | 2018 |
5-HT
Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; HeLa Cells; Humans; Male; Maze Learning; Memory; Mice, Inbred ICR; Nootropic Agents; Piperidines; Pyridones; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Thiophenes; Vilazodone Hydrochloride | 2018 |
The 5-HT6R agonist E-6837 and the antagonist SB-271046 reverse the psychotic-like behaviors induced by ketamine.
Topics: Animals; Antipsychotic Agents; Humans; Indoles; Ketamine; Memory Disorders; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Sulfonamides; Thiophenes | 2022 |
5-HT6 Receptors Sex-Dependently Modulate Hippocampal Synaptic Activity through GABA Inhibition.
Topics: Animals; Female; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Synaptic Transmission; Thiophenes | 2023 |